Sample container box for a ventilated biological irradiator
Patent Information
- Application Number
- CN202522132870.0
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-10-09
- Publication Date
- 2026-09-04
- Estimated Expiration
- 2035-10-09
AI Technical Summary
[0004]本申请的目的是提供一种通气式生物辐照仪用样本容器盒，具备便于提高生物样本的存活率，保证实验效果等优点，解决了现有的生物容器盒，承载生物样本时由于生物样本需要进行呼吸，需要消耗氧气，由于密闭无通气孔的容器内部氧气有限，在生物呼吸时逐渐消耗氧气，同时蓄积二氧化碳，造成二氧化碳浓度过高，可能会导致样本因缺氧而造成死亡，使辐照后的样本无法满足后续研究或培养需求，导致实验失败
该一种通气式生物辐照仪用样本容器盒，通过采用碳纤维材质的盒体，配合固定环上的第一通气孔与突盖上对应的第二通气孔形成顺畅气流通道，为内部生物提供持续氧气并排出代谢气体，同时上盖内的纱网在不影响通气的情况下阻挡样本逃逸和外界杂质进入，上盖通过插环与盒体插槽的嵌合及卡扣与卡槽的卡接实现紧密盖合，确保上盖的连接稳定性，避免样本泄漏或上盖松动，上盖的提手便于上盖的安全开启或关闭，防止操作时滑落，盒体底端的槽口与辐照仪反应仓转盘的凸台配合，确保容器精准定位，避免因设备运行发生偏移，外螺纹环与内螺纹环的螺纹连接使得两个容器在堆叠时更加稳固，便于批量处理样本，且堆叠后通气孔仍能保持对应畅通，该装置通过固定环和第一通气孔、突盖和第二通气孔的设置，在保障生物活性的同时，满足生物辐照实验的需求。
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Figure CN224715536U_ABST
Abstract
Description
Technical Field
[0001] This application relates to the field of bioirradiation technology, and in particular to a sample container box for a ventilated bioirradiator. Background Technology
[0002] Currently, bio-irradiation technology is widely used in biomedical research, food microbial inactivation, and pharmaceutical irradiation sterilization. Its core is to use controlled doses of radiation to act on biological samples to achieve experimental research or disinfection and sterilization purposes. In this process, biological samples need to be placed in a container and then placed in a bio-irradiation instrument to complete the irradiation treatment.
[0003] However, existing biological containers, when holding biological samples, require oxygen to breathe. Since the oxygen inside the sealed container without ventilation holes is limited, the oxygen is gradually consumed during biological respiration, while carbon dioxide accumulates, causing the carbon dioxide concentration to become too high. This may lead to the death of the sample due to hypoxia, making the irradiated sample unsuitable for subsequent research or culture, resulting in experimental failure. Utility Model Content
[0004] The purpose of this application is to provide a sample container for a ventilated biological irradiator, which has the advantages of improving the survival rate of biological samples and ensuring experimental results. It solves the problem that existing biological containers, when holding biological samples, require oxygen to breathe. Since the oxygen inside the sealed container without ventilation holes is limited, the oxygen is gradually consumed during biological respiration, and carbon dioxide accumulates, resulting in excessively high carbon dioxide concentration. This may cause the samples to die due to hypoxia, making the irradiated samples unsuitable for subsequent research or culture, leading to experimental failure.
[0005] The sample container box for a ventilated biological irradiator provided in this application adopts the following technical solution: A sample container box for a ventilated biological irradiator includes two carbon fiber boxes and a top cover. The bottom ends of the two carbon fiber boxes are fixedly connected to a fixing ring. The outer walls of the two fixing rings are provided with a plurality of first ventilation holes arranged in a ring array. The bottom ends of the two fixing rings are fixedly connected to an internal threaded ring. The top ends of the two top covers are fixedly connected to a protruding cover. The outer walls of the two protruding covers are provided with a plurality of second ventilation holes arranged in a ring array. The top ends of the two top covers are fixedly connected to an external threaded ring.
[0006] By adopting the above technical solution, multiple first ventilation holes arranged in a ring array are set on the fixing ring at the bottom of the carbon fiber box, and multiple second ventilation holes arranged in a ring array are correspondingly set on the protruding cover of the top cover. After the upper and lower containers are combined, external oxygen can enter the interior of the carbon fiber box through the first and second ventilation holes, so that the interior of the container can form a smooth air circulation with the outside, providing a continuous oxygen supply for the organisms carried in the container, and timely expelling metabolic gases, avoiding sample inactivation due to the sealed environment, and ensuring that the irradiated samples can still meet the needs of subsequent research or culture. The internal threaded ring at the bottom of the fixing ring and the external threaded ring at the top of the top cover can cooperate to achieve a stable connection between the two containers, preventing them from falling off when stacked. At the same time, the carbon fiber box not only has good structural strength, which can effectively protect the internal samples, but also does not significantly hinder the penetration of irradiation rays, ensuring the uniformity of the irradiation process. Through the carbon fiber box and the setting of the first and second ventilation holes, this device has good ventilation performance to ensure the biological activity inside the container and improve the reliability of biological irradiation experiments.
[0007] Preferably, both of the top covers are fixedly connected with mesh.
[0008] By adopting the above technical solution, a mesh is fixedly connected inside the top cover. The mesh not only does not block the airflow path formed by the first and second ventilation holes, ensuring normal air exchange between the inside and outside of the container to maintain the activity of live animal samples, but also prevents live animals from escaping through the first and second ventilation holes when the samples are moving. At the same time, it can also intercept dust and impurities from the external environment to enter the box and contaminate the samples. Thus, while ensuring ventilation, it forms a protective barrier to prevent sample escape and further improves the safety of samples and the accuracy of experimental results during biological irradiation.
[0009] Preferably, each of the two top covers has a fixedly connected insert ring at its bottom, and each of the two carbon fiber boxes has a slot at its top, with the two insert rings slidably disposed inside the slot.
[0010] By adopting the above technical solution, by fixing the insert ring at the bottom inside the top cover and opening the slot at the top of the carbon fiber box, when the container is closed, simply align the insert ring of the top cover with the slot of the carbon fiber box and slide it in to allow the insert ring and the slot to fit together, forming a seal between the carbon fiber box and the top cover, which enhances the sealing performance and sample protection of the container, and ensures the stability of the sample environment during biological irradiation.
[0011] Preferably, each of the two top covers is fixedly connected to three buckles arranged in a circular array at its bottom end, and a slot is provided on the upper end of the outer wall of the carbon fiber box, with the ends of the multiple buckles slidably disposed inside the slot away from the top cover.
[0012] By adopting the above technical solution, three buckles arranged in a ring array are set at the bottom of the top cover, and corresponding slots are opened on the upper part of the outer wall of the carbon fiber box. When the top cover is closed, the buckles will slide into the slots as the top cover moves down and form a stable engagement. This can further strengthen the connection between the top cover and the box body based on the cooperation of the insertion ring and the slot, and prevent the top cover from becoming loose or falling off during movement or handling. While ensuring ease of operation, it also improves the overall sealing stability of the container box, ensuring that the sample is in a safe and stable environment during biological irradiation.
[0013] Preferably, each of the two outer walls of the cover is fixedly connected to three handles arranged in a circular array.
[0014] By adopting the above technical solution, three handles arranged in a ring array are fixed on the upper part of the outer wall of the cover. The handles provide a good force position for opening the cover, preventing the container from falling and damaging the sample due to slipping. This improves the convenience and safety of operation and reduces the risk of sample damage.
[0015] Preferably, both of the carbon fiber boxes have slots at their bottom ends.
[0016] By adopting the above technical solution, a slot is opened at the bottom of the carbon fiber box. When the container is placed on the stage of the biological irradiator, the slot can cooperate with the boss on the reaction chamber turntable, so that the container is accurately positioned in the preset position and will not shift or shake due to the rotation of the turntable or the vibration of the equipment. This ensures that the sample inside the box is always in the set irradiation area and guarantees the uniformity and stability of the irradiation dose.
[0017] Preferably, the external threaded ring is threaded inside the internal threaded ring.
[0018] By adopting the above technical solution, an external threaded ring is set inside the internal threaded ring, enabling the two container boxes to be stably connected through the threaded structure. The two container boxes are stacked in sequence, and the external threaded ring of the upper container box and the internal threaded ring of the lower container box are screwed together to form a whole. This ensures the stability of the overall structure after stacking, facilitates the simultaneous irradiation treatment of batch samples, and avoids the container boxes from tipping over due to rotation or vibration caused by equipment operation during irradiation. At the same time, the threaded connection method also makes the assembly and disassembly of the container boxes simple.
[0019] Preferably, each of the plurality of first vent holes corresponds to a second vent hole.
[0020] By adopting the above technical solution, and by making multiple first vents correspond to second vents, when the upper and lower containers are connected, the first vents on the fixing ring and the second vents on the protruding cover can form corresponding airflow channels. Outside air can enter the container through the first and second vents in sequence, while the gas inside the container can also be discharged, ensuring smooth air circulation, providing a continuous oxygen supply for the organisms inside the container, and timely discharging the gases produced by metabolism, avoiding sample inactivation due to poor gas exchange. While ensuring the normal survival environment of the samples, it provides basic support for the accuracy of biological irradiation experiments.
[0021] In summary, this application includes at least one of the following beneficial technical effects: This ventilated biological irradiator sample container uses a carbon fiber body. A first vent on the fixing ring and a corresponding second vent on the protruding cover form a smooth airflow channel, providing continuous oxygen to the internal organisms and expelling metabolic gases. Simultaneously, the mesh inside the cover prevents sample escape and the entry of external impurities without affecting ventilation. The cover achieves a tight seal through the interlocking of a ring with a slot in the body and the snap-fit of a buckle with a slot, ensuring the stability of the cover connection and preventing sample leakage or loosening. A handle on the cover facilitates safe opening and closing, preventing slippage during operation. A groove at the bottom of the body engages with a protrusion on the irradiator's reaction chamber turntable, ensuring precise container positioning and preventing displacement due to equipment operation. The threaded connection between the external and internal threaded rings makes stacking two containers more stable, facilitating batch sample processing, and ensuring that the vents remain unobstructed even after stacking. This device, through the fixing ring, the first vent, the protruding cover, and the second vent, meets the needs of biological irradiation experiments while ensuring biological activity. Attached Figure Description
[0022] Figure 1 This is a schematic diagram of the overall structure of this application; Figure 2 This is a schematic diagram of the box structure of this application; Figure 3 This is a schematic diagram of the upper cover structure of this application; Figure 4 This is a schematic diagram of the internal structure of the upper cover of the structure in this application; Figure 5 This is a schematic diagram of the connection structure between the boxes in this application. Figure 6 This is a cross-sectional view of the box structure of this application.
[0023] In the picture: 1. Carbon fiber box body; 2. Fixing ring; 3. First vent hole; 4. Internal threaded ring; 5. Top cover; 6. Protruding cover; 7. Second vent hole; 8. External threaded ring; 9. Mesh; 10. Insert ring; 11. Buckle; 12. Slot; 13. Slot; 14. Handle; 15. Groove. Detailed Implementation
[0024] The following is in conjunction with the appendix Figure 1 -Appendix Figure 6 This application will be described in further detail below.
[0025] Example 1: A sample container box for a ventilated biological irradiator, referring to... Figure 1 , Figure 2 and Figure 3 The device includes two carbon fiber boxes 1 and a top cover 5. The carbon fiber boxes not only possess excellent structural strength, effectively protecting the internal samples, but also do not significantly obstruct the penetration of irradiation rays, ensuring uniformity during the irradiation process. Each of the two carbon fiber boxes 1 has a fixing ring 2 fixedly connected to its bottom. The outer walls of each fixing ring 2 have multiple first ventilation holes 3 arranged in a ring array. The bottom of each fixing ring 2 is fixedly connected to an internally threaded ring 4. Each of the two top covers 5 has a protruding cap 6 fixedly connected to its upper end. The outer walls of each protruding cap 6 have multiple second ventilation holes 7 arranged in a ring array. By providing multiple first ventilation holes 3 arranged in a ring array on the fixing rings 2 at the bottom of the carbon fiber boxes 1, and simultaneously providing second ventilation holes 7 on the protruding caps 5... Multiple second ventilation holes 7 arranged in a ring array are set on the upper part. After the upper and lower containers are combined, external oxygen can enter the interior of the carbon fiber box 1 through the first ventilation hole 3 and the second ventilation hole 7, so that the interior of the container can form a smooth air circulation with the outside, providing a continuous oxygen supply for the organisms carried in the container and timely expelling the gases produced by metabolism, avoiding sample inactivation due to the sealed environment, and ensuring that the irradiated sample can still meet the needs of subsequent research or culture. The upper ends of the two upper covers 5 are fixedly connected with external threaded rings 8. The internal threaded ring 4 at the bottom of the fixing ring 2 cooperates with the external threaded ring 8 at the top of the upper cover 5, which can realize a stable connection between the two containers, prevent the two containers from falling off when stacked, and improve the reliability of biological irradiation experiments.
[0026] Example 2: A sample container box for a ventilated biological irradiator, referring to... Figure 4 , Figure 5 and Figure 6Both top covers 5 have mesh screens 9 fixedly connected inside. This mesh screen 9 not only prevents obstruction of the airflow path formed by the first ventilation hole 3 and the second ventilation hole 7, ensuring normal air exchange between the inside and outside of the container to maintain the activity of live animal samples, but also prevents live animals from escaping through the ventilation holes 3 and 7 during sample movement. It also intercepts dust and impurities from the external environment, preventing them from entering the container and contaminating the samples. Thus, while ensuring ventilation, it also provides protection against sample escape, further improving the safety of samples and the accuracy of experimental results during biological irradiation. Both top covers 5 have insert rings fixedly connected to their bottom ends. 10. Each of the two carbon fiber box bodies 1 has a slot 13 at its upper end, and two insert rings 10 are slidably disposed inside the slot 13. By fixing the insert rings 10 to the bottom inside the upper cover 5 and opening the slot 13 at the upper end of the carbon fiber box body 1, when the container is closed, simply align the insert rings 10 of the upper cover 5 with the slots 13 of the carbon fiber box body 1 and slide them in to form a fitting between the insert rings 10 and the slots 13, creating a seal between the carbon fiber box body 1 and the upper cover 5. This enhances the sealing performance and sample protection of the container, ensuring the stability of the sample environment during biological irradiation. Each of the two upper covers 5 has three buckles 11 fixedly connected to its bottom end in a circular array. The upper end of the outer wall of the carbon fiber box body 1 has a slot 12, and the multiple buckles 11 are located away from the upper part of the upper cover. One end of the cover 5 is slidably positioned inside the slot 12. Three buckles 11 arranged in a circular array are provided at the bottom of the cover 5, and a corresponding slot 12 is provided on the upper part of the outer wall of the carbon fiber box 1. When the cover 5 is closed, the buckles 11 slide into the slot 12 as the cover 5 moves downwards, forming a secure engagement. This further strengthens the connection between the cover 5 and the box body, based on the engagement of the insertion ring 10 and the slot 13, preventing the cover 5 from loosening or falling off during movement or handling. While ensuring ease of operation, this improves the overall sealing stability of the container, ensuring that the sample is in a safe and stable environment during biological irradiation. Three handles 14 arranged in a circular array are fixedly connected to the upper part of the outer wall of each of the two covers 5. By fixing three handles 14 arranged in a ring on the upper part of the outer wall of the top cover 5, the handles 14 provide a good force position for opening the top cover 5, preventing the container box from falling and damaging the sample due to slipping, improving the convenience and safety of operation, and reducing the risk of sample damage. Both carbon fiber boxes 1 have slots 15 at the bottom. When the container box is placed on the stage of the biological irradiation instrument, the slots 15 can cooperate with the bosses on the reaction chamber turntable, so that the container box is accurately positioned in the preset position, and will not be offset or shaken due to the rotation of the turntable or the vibration of the equipment, ensuring that the sample inside the box is always in the set irradiation area, and ensuring the uniformity and stability of the irradiation dose.
[0027] Reference Figure 1 , Figure 5 and Figure 6 An external threaded ring 8 is threaded inside an internal threaded ring 4. By threading an external threaded ring 8 inside an internal threaded ring 4, the two container boxes can be stably connected through the threaded structure. The two container boxes are stacked sequentially, and the external threaded ring 8 of the upper container box and the internal threaded ring 4 of the lower container box are screwed together to form a whole. This ensures the stability of the overall structure after stacking, facilitates the simultaneous irradiation of batch samples, and prevents the container boxes from tipping over due to rotation or vibration caused by equipment operation during irradiation. At the same time, the threaded connection method also makes the assembly and disassembly of the container boxes simple. Multiple first vent holes 3 are also used for second vents. The holes 7 correspond to each other. By aligning multiple first vent holes 3 with second vent holes 7, when the upper and lower containers are connected, the first vent holes 3 on the fixing ring 2 and the second vent holes 7 on the protruding cover 6 can form corresponding airflow channels. Outside air can enter the container through the first vent holes 3 and the second vent holes 7 in sequence, while the gas inside the container can also be discharged, ensuring smooth air circulation, providing a continuous oxygen supply for the organisms inside the container, and timely expelling metabolic gases to avoid sample inactivation due to poor gas exchange. While ensuring the normal survival environment of the samples, it provides basic support for the accuracy of biological irradiation experiments.
[0028] The implementation principle of this application embodiment is as follows: In use, the biological sample to be processed is first placed into the two carbon fiber boxes 1. The carbon fiber material can protect the sample while not hindering the penetration of the irradiation rays, ensuring uniform irradiation. Then, the top cover 5 is closed. During the closing process, the insertion ring 10 at the bottom of the top cover 5 is aligned with the slot 13 at the top of the carbon fiber box 1 and slid in to form an initial fitting and positioning, ensuring that the top cover 5 is precisely aligned with the box. As the top cover 5 continues to move down, the buckle 11 at the bottom of the top cover 5 will simultaneously slide into the slot 12 on the outer wall of the carbon fiber box 1 to form a stable engagement, further strengthening the connection stability and preventing the top cover 5 from loosening or falling off during irradiation, which could lead to sample leakage. Then, the external thread ring 8 of the bottom container top cover 5 is aligned with the internal thread ring 4 at the bottom of the top container, and the threads are tightened to achieve a stable connection, forming an integral structure to prevent the stacked boxes from tipping over during equipment operation. The two carbon fiber boxes 1, after being assembled, are moved to the stage of the biological irradiator. At the top, when placed, the groove 15 at the bottom of the carbon fiber box 1 aligns with the boss on the turntable of the irradiator reaction chamber to achieve precise positioning of the container box, preventing the container box from shifting due to turntable rotation or equipment vibration, and ensuring that the sample is always in the set irradiation area. During irradiation, the first vent 3 on the fixing ring 2 and the second vent 7 on the protruding cover 6 are pre-aligned to form a through airflow channel, allowing outside air to smoothly enter the container box, providing continuous oxygen to the sample, while timely expelling metabolic gases to prevent the sample from becoming inactive due to hypoxia. The mesh 9 inside the top cover 5 will prevent the sample from escaping through the vents without blocking the ventilation channel, and at the same time intercept external dust and impurities from entering the box and contaminating the sample. This device ensures the stability and accuracy of the irradiation process while guaranteeing the activity and safety of the sample. After irradiation, the container box can be removed, and the stacked boxes can be disassembled by loosening the threads to remove the sample for subsequent research or culture.
Claims
1. A sample container for a ventilated biological irradiator, comprising two carbon fiber housings (1) and a top cover (5), characterized in that: The bottom ends of the two carbon fiber boxes (1) are fixedly connected to a fixing ring (2), and the outer walls of the two fixing rings (2) are provided with multiple first ventilation holes (3) arranged in a ring array. The bottom ends of the two fixing rings (2) are fixedly connected to an internal threaded ring (4). The upper ends of the two top covers (5) are fixedly connected to a protruding cover (6), and the outer walls of the two protruding covers (6) are provided with multiple second ventilation holes (7) arranged in a ring array. The upper ends of the two top covers (5) are fixedly connected to an external threaded ring (8).
2. The sample container box for a ventilated biological irradiator according to claim 1, characterized in that: Both of the top covers (5) have mesh (9) fixedly connected inside.
3. The sample container box for a ventilated biological irradiator according to claim 1, characterized in that: Both of the top covers (5) have a fixed ring (10) at the bottom inside, and both of the carbon fiber boxes (1) have a slot (13) at the top. Both of the rings (10) are slidably disposed inside the slot (13).
4. The sample container box for a ventilated biological irradiator according to claim 1, characterized in that: The bottom ends of the two top covers (5) are fixedly connected to three buckles (11) arranged in a ring array. The upper end of the outer wall of the carbon fiber box (1) is provided with a slot (12). The ends of the multiple buckles (11) away from the top cover (5) are slidably arranged inside the slot (12).
5. A sample container box for a ventilated biological irradiator according to claim 1, characterized in that: Three handles (14) arranged in a circular array are fixedly connected to the upper end of the outer wall of each of the two top covers (5).
6. A sample container box for a ventilated biological irradiator according to claim 1, characterized in that: Both of the carbon fiber boxes (1) have slots (15) at their bottom ends.
7. A sample container box for a ventilated biological irradiator according to claim 1, characterized in that: The external threaded ring (8) is threaded inside the internal threaded ring (4).
8. A sample container box for a ventilated biological irradiator according to claim 1, characterized in that: Each of the first vent holes (3) corresponds to a second vent hole (7).