Rapid sample pre-treatment configuration for iron balance test kits

Abstract

The utility model discloses a quick sample pre -processing structure of iron balance detection reagent box, including mounting bracket, be equipped with the processing box through the installation channel on the mounting bracket, be equipped with the rotary chamber and the movable chamber in the processing box, the rotary chamber is equipped with the reciprocating screw rod of extending to the installation channel rotation in, be equipped with the drive motor fixed on the mounting bracket, the drive motor is connected with reciprocating screw rod through the rotating mechanism, be equipped with the piston board in the movable chamber, the piston board is connected with reciprocating screw rod through the link mechanism, the processing box is installed with the feed pipe and the discharge pipe.

Description

Technical Field

[0001] This invention relates to the field of biomedical detection technology, and in particular to a rapid sample pretreatment structure for an iron balance detection kit. Background Technology

[0002] In iron balance assays, sample pretreatment (such as blood, serum, and tissue homogenates) is crucial for ensuring accurate results. This is because samples often contain particulate impurities, including cell debris, protein polymers, and fibers, in addition to the target substances like iron ions and iron-binding proteins. If these impurities directly enter the detection system, they may react non-specifically with the reagents or clog the instrument's channels, interfering with the detection signal and leading to deviations in the measurement results of iron balance-related indicators. Therefore, sample pretreatment is essential, and filtration is an indispensable step in this process. Its purpose is to remove these particulate impurities, providing a pure sample matrix for subsequent assays.

[0003] In existing technologies, devices used for sample pretreatment in iron balance testing often employ a single-stage filtration design. This means that the filtration structure is only installed at the single stage of sample entry into or exit from the processing device, relying on a single filtration to remove impurities. However, due to the complex composition and varying concentrations of impurities in the sample, single filtration often fails to completely remove them. Some fine particles or newly generated precipitates during processing may remain in the sample, affecting the accuracy of subsequent detections and failing to fully meet the sample purity requirements for iron balance testing. Utility Model Content

[0004] The purpose of this invention is to address the shortcomings of existing technologies by proposing a rapid sample pretreatment structure for an iron balance detection kit.

[0005] To achieve the above objectives, the present invention adopts the following technical solution: A rapid sample pretreatment structure for an iron balance detection kit includes a mounting frame. A processing chamber is mounted on the mounting frame via a mounting channel. The processing chamber contains a rotating chamber and a movable chamber. A reciprocating screw extending into the mounting channel is rotatably mounted within the rotating chamber. A drive motor is fixedly mounted on the mounting frame and connected to the reciprocating screw via a rotating mechanism. A piston plate is located within the movable chamber and connected to the reciprocating screw via a connecting mechanism. An inlet pipe and an outlet pipe are mounted on the processing chamber, both equipped with filter components. The mounting frame has a movable channel, within which a fixed plate is fixed. A movable frame slides through the fixed plate via an elastic mechanism. A positioning groove is located on the outer wall of the processing chamber.

[0006] Preferably, the rotating mechanism includes a first gear fixedly mounted on the output shaft of the drive motor, and a second gear meshing with the first gear is fixedly mounted on the reciprocating screw.

[0007] Preferably, the connecting mechanism includes a connecting frame threaded onto a reciprocating screw, the end of which is fixedly connected to a piston plate.

[0008] Preferably, the elastic mechanism includes a spring sleeved on the outside of the movable frame rod, with both ends of the spring connected to the outer wall of the movable frame and the outer wall of the fixed plate, respectively.

[0009] Preferably, both the feed pipe and the discharge pipe are equipped with valves, and both valves are one-way valves.

[0010] Preferably, the mounting frame has multiple support legs installed at the bottom, and the processing box has a lifting handle fixedly provided on the upper surface.

[0011] The beneficial effects of this utility model are: 1. The filter components on the feed pipe and the discharge pipe form a dual filtration system, which can more thoroughly intercept impurities and significantly improve sample purity compared to single filtration, providing a reliable matrix for subsequent detection.

[0012] 2. The movable frame and positioning slot work together to achieve stable positioning of the processing box. When picking up or putting down the box, simply drag the movable frame and pull the handle for quick operation, which solves the problems of unstable positioning and cumbersome picking and putting down.

[0013] 3. The drive motor drives the reciprocating screw through gear transmission, which, together with the connecting frame, drives the piston plate to lift and lower stably, avoiding problems such as insufficient sample intake and residual sample discharge caused by unstable power, thus improving pretreatment efficiency and consistency.

[0014] 4. The one-way valve controls the unidirectional flow of materials to prevent sample backflow and cross-contamination, ensuring the safety of pretreatment and the purity of the samples. Attached Figure Description

[0015] Figure 1 This is a schematic diagram of the rapid sample pretreatment structure of the iron balance detection kit proposed in this utility model. Figure 2 for Figure 1 A schematic diagram of the structure viewed from below; Figure 3 for Figure 1 A schematic diagram of the vertical section structure; Figure 4 for Figure 3 An enlarged schematic diagram of the structure at point A.

[0016] In the diagram: 1. Mounting frame, 2. Mounting channel, 3. Processing box, 4. Feed pipe, 5. Discharge pipe, 6. Filter assembly, 7. Movable channel, 8. Movable frame, 9. Reciprocating screw, 10. Drive motor, 11. First gear, 12. Second gear, 13. Rotating chamber, 14. Movable chamber, 15. Connecting frame, 16. Piston plate, 17. Valve, 18. Fixing plate, 19. Spring, 20. Positioning groove. Detailed Implementation

[0017] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present utility model. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments.

[0018] Reference Figure 1-4 The rapid sample pretreatment structure of the iron balance detection kit includes a mounting frame 1. A processing chamber 3 is mounted on the mounting frame 1 via a mounting channel 2. Inside the processing chamber 3 are a rotating chamber 13 and a movable chamber 14. A reciprocating screw 9 extending into the mounting channel 2 rotates within the rotating chamber 13. A drive motor 10 is fixedly mounted on the mounting frame 1 and connected to the reciprocating screw 9 via a rotating mechanism. A piston plate 16 is located within the movable chamber 14 and is connected to the reciprocating screw 9 via a connecting mechanism. An inlet pipe 4 and an outlet pipe 5 are mounted on the processing chamber 3. Both the inlet pipe 4 and the outlet pipe 5 are equipped with a filter assembly 6. The filter assembly 6 consists of pipes and a filter membrane. The filter membrane is a mixed cellulose ester membrane or a polyethersulfone membrane with a pore size of 0.22 μm or 0.45 μm. It filters out particulate impurities through sieving while allowing target substances such as iron ions and iron-binding proteins to pass through. Since this is a common product in existing technology, its specific working principle will not be elaborated here.

[0019] The mounting frame 1 is provided with a movable channel 7, and a fixed plate 18 is fixedly installed in the movable channel 7. The movable frame 8 is slidably installed through the fixed plate 18 by an elastic mechanism. The outer wall of the processing box 3 is provided with a positioning groove 20.

[0020] The rotating mechanism includes a first gear 11 fixedly mounted on the output shaft of the drive motor 10, and a second gear 12 fixedly mounted on the reciprocating screw 9, meshing with the first gear 11. The drive motor 10 is mounted on the mounting bracket 1 via a motor base, and its output shaft is connected to the first gear 11 via a coupling. The reciprocating screw 9 has threaded grooves only on the outer wall of the portion inside the rotating chamber 13. Power transmission from the drive motor 10 is achieved by the first gear 11 and the second gear 12, allowing the reciprocating screw 9 to rotate after the drive motor 10 is powered on and started.

[0021] The connecting mechanism includes a connecting frame 15 threaded onto the reciprocating screw 9, with the end of the connecting frame 15 fixedly connected to the piston plate 16. As shown in the figure, the connecting frame 15 has a U-shaped design, with its vertical part sliding through the inner wall of the rotating chamber 13 and extending into the movable chamber 14. Therefore, it has its own limit and will not rotate with the reciprocating screw 9.

[0022] The elastic mechanism includes a spring 19 sleeved on the outside of the movable frame 8 rod, with both ends of the spring 19 connected to the outer wall of the movable frame 8 and the outer wall of the fixed plate 18, respectively. The elastic potential energy provided by the spring 19 enables the stable holding operation of the movable frame 8, ensuring that part of the movable frame 8 enters the positioning groove 20, thereby ensuring that the processing box 3 is stably placed in the installation channel 2.

[0023] Both the feed pipe 4 and the discharge pipe 5 are equipped with valves 17, and both valves 17 are one-way valves. The above-mentioned one-way valves realize the one-way flow of materials.

[0024] The mounting bracket 1 has multiple support legs installed at its bottom, and the processing box 3 has a lifting handle fixed to its upper surface. See the attached diagram for details. The support legs provide support for the mounting bracket 1, and the lifting handle facilitates the lifting operation of the processing box 3.

[0025] Working principle of this utility model: Sample intake and processing: When the drive motor 10 starts, it drives the reciprocating screw 9 to rotate via the first gear 11 and the second gear 12. Since the connecting frame 15 is threadedly connected to the reciprocating screw 9 and has its own limiting function, the rotation of the reciprocating screw 9 will cause the connecting frame 15 to drive the piston plate 16 to descend within the movable chamber 14. At this time, the one-way valve on the feed pipe 4 opens and the one-way valve on the discharge pipe 5 closes. Under the negative pressure generated by the descent of the piston plate 16, the sample to be processed enters through the feed pipe 4, is filtered by the filter assembly 6, and then enters the movable chamber 14.

[0026] Sample extrusion and discharge: When the piston plate 16 rises, the one-way valve on the feed pipe 4 closes and the one-way valve on the discharge pipe 5 opens. The pre-treated sample is discharged through the discharge pipe 5 under pressure, and after being filtered again by the filter assembly 6, it enters the subsequent stage.

[0027] Dual-sided filtration ensures effective pretreatment.

[0028] Removing and placing the processing box 3: When it is necessary to remove the processing box 3, drag the movable frame 8 to stretch the spring 19 and disengage it from the positioning groove 20, thereby releasing the positioning restriction on the processing box 3. Then, the processing box 3 can be vertically removed from the installation channel 2 by pulling the handle. During installation, place the processing box 3 into the installation channel 2. Under the action of the elastic potential energy of the spring 19, the movable frame 8 enters the positioning groove 20 to achieve stable installation of the processing box 3.

[0029] The above description is only a preferred embodiment of the present utility model, but the protection scope of the present utility model is not limited thereto. Any equivalent substitutions or changes made by those skilled in the art within the technical scope disclosed in the present utility model, based on the technical solution and the inventive concept of the present utility model, should be included within the protection scope of the present utility model.

Claims

1. A rapid sample pretreatment structure for an iron balance detection kit, comprising a mounting frame (1), characterized in that, The mounting frame (1) is provided with a processing box (3) through the mounting channel (2). The processing box (3) is provided with a rotating chamber (13) and a movable chamber (14). The rotating chamber (13) is provided with a reciprocating screw (9) extending into the mounting channel (2). The mounting frame (1) is fixedly provided with a drive motor (10). The drive motor (10) is connected to the reciprocating screw (9) through a rotating mechanism. The movable chamber (14) is provided with a piston plate (16). The piston plate (16) is connected to the reciprocating screw (9) through a connecting mechanism. The processing box (3) is provided with a feed pipe (4) and a discharge pipe (5). Both the feed pipe (4) and the discharge pipe (5) are provided with filter components (6). The mounting frame (1) is provided with a movable channel (7). The movable channel (7) is fixedly provided with a fixed plate (18). The fixed plate (18) is slidably provided with a movable frame (8) through an elastic mechanism. The outer wall of the processing box (3) is provided with a positioning groove (20).

2. The rapid sample pretreatment structure of the iron balance detection kit according to claim 1, characterized in that, The rotating mechanism includes a first gear (11) fixedly mounted on the output shaft of the drive motor (10), and a second gear (12) fixedly mounted on the reciprocating screw (9) meshing with the first gear (11).

3. The rapid sample pretreatment structure of the iron balance detection kit according to claim 2, characterized in that, The connecting mechanism includes a connecting frame (15) threadedly mounted on a reciprocating screw (9), and the end of the connecting frame (15) is fixedly connected to a piston plate (16).

4. The rapid sample pretreatment structure of the iron balance detection kit according to claim 3, characterized in that, The elastic mechanism includes a spring (19) sleeved on the outside of the rod of the movable frame (8), with the two ends of the spring (19) connected to the outer wall of the movable frame (8) and the outer wall of the fixed plate (18), respectively.

5. The rapid sample pretreatment structure of the iron balance detection kit according to claim 4, characterized in that, Both the feed pipe (4) and the discharge pipe (5) are equipped with valves (17), and both valves (17) are one-way valves.

6. The rapid sample pretreatment structure of the iron balance detection kit according to claim 5, characterized in that, The mounting bracket (1) has multiple support legs installed at its bottom, and the processing box (3) has a lifting handle fixedly installed on its upper surface.

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