A crystallization apparatus for purifying batyl alcohol

Abstract

The application discloses a device for purifying and crystallizing batyl alcohol, and particularly relates to the technical field of recrystallization, which comprises a recrystallization kettle, a kettle cover is arranged on the top of the recrystallization kettle, a driving motor is arranged on the top of the kettle cover, a planetary gear set is arranged at the bottom of the kettle cover, a screw shaft is coaxially and fixedly connected with the output end of the driving motor and coaxially and fixedly connected with the sun gear of the planetary gear set, an inner circulation pipe is coaxially and fixedly connected with the planet carrier of the planetary gear set, the top and the bottom of the inner circulation pipe are extended with branch pipes, a plurality of through holes are formed in each branch pipe and communicated with the inner cavity of the recrystallization kettle, and a scraper plate is extended from the inner circulation pipe and adheres to the inner wall of the recrystallization kettle. The high-speed rotating screw shaft is matched with the inner circulation pipe to realize the efficient up-and-down circulation of the solution, the axial rotation and stirring of the inner circulation pipe and the scraper plate realize the transverse circulation of the solution, and the size of the generated batyl alcohol crystals is uniform.

Description

Technical Field

[0001] This utility model belongs to the field of recrystallization technology, specifically relating to a shark liver alcohol purification and crystallization device. Background Technology

[0002] Squalene is a compound that promotes leukocyte proliferation and has anti-radiation effects. It can be used to treat leukopenia and leukopenia caused by radioactive drugs. Recrystallization is often used to improve the purity of squalene crystals during purification.

[0003] Existing recrystallization devices typically only have simple stirrs, which can only stir axially inside the vessel. Because the stirring radius and stirrer shape are fixed, dead zones are easily created. For example, Chinese patent CN222286444U discloses a nicosulfuron recrystallization stirring device, which "by setting a drive component, when the servo motor drives the rotating shaft to rotate inside the reactor, the stirring plate rotates axially inside the reactor while simultaneously sliding laterally back and forth inside the reactor, constantly changing the stirring radius. This can break up local stagnation zones in the solution, reduce dead zones, further enhance mixing uniformity, and allow nicosulfuron crystals to be evenly distributed in the solution, avoiding crystal aggregation or clumping." However, axial rotation alone cannot achieve efficient vertical circulation of the solution, causing crystals to easily accumulate at the bottom of the tank, resulting in uneven crystal size and affecting the accurate weighing and use of squalene.

[0004] Therefore, a new type of shark liver alcohol purification and crystallization device is needed. Utility Model Content

[0005] To address the aforementioned problems, this utility model discloses a squalene purification and crystallization apparatus.

[0006] To achieve the above objectives, the technical solution of this utility model is as follows:

[0007] A squalene purification and crystallization apparatus includes a recrystallization vessel. The top of the recrystallization vessel is covered with a lid, a drive motor is installed on the top of the lid, and a planetary gear set is installed at the bottom of the lid. The output end of the drive motor is coaxially and fixedly connected to an auger shaft, which is coaxially and fixedly connected to the sun gear of the planetary gear set. The planetary carrier of the planetary gear set is coaxially and fixedly connected to an inner circulation pipe, and the auger shaft extends into the main pipe of the inner circulation pipe. The sun gear meshes with several planetary gears, and the planetary gears mesh with a gear ring fixedly connected to the lid. Each planetary gear is rotatably connected to the planetary carrier. Branch pipes extend from the top and bottom of the inner circulation pipe, and each branch pipe has several through holes communicating with the inner cavity of the recrystallization vessel. A scraper extends from the inner circulation pipe and fits against the inner wall of the recrystallization vessel.

[0008] In a preferred embodiment of this invention, the diameter of the planetary gear is larger than the diameter of the sun gear.

[0009] As a preferred embodiment of this utility model, the gear ring is provided with an annular groove, and the annular groove is provided with a number of balls that together lift the planetary carrier.

[0010] As a preferred embodiment of this utility model, the auger shaft is fixedly sleeved with a first retaining ring, and the first retaining ring does not contact the inner circulation pipe. The inner wall of the main pipe of the inner circulation pipe is fixedly inlaid with a second retaining ring, and the second retaining ring does not contact the auger shaft. Both the first retaining ring and the second retaining ring are located above the extension of the top branch pipe of the inner circulation pipe.

[0011] As a preferred embodiment of this utility model, the auger shaft is fixedly fitted with a sealed bearing, and the outer ring of the sealed bearing is fixedly embedded in the main pipe of the inner circulation pipe. The sealed bearing is positioned above the first retaining ring and the second retaining ring.

[0012] As a preferred embodiment of this utility model, the side wall of the recrystallization vessel is inlaid with a spiral temperature control tube, and both ends of the temperature control tube are connected to an electromagnetic three-way valve for switching the external hot and cold circulation pipeline.

[0013] As a preferred embodiment of this utility model, the recrystallization vessel is connected to a mounting frame, and the protrusions at both ends of the recrystallization vessel are vertically slidably inserted into the two vertical rods of the mounting frame.

[0014] As a preferred embodiment of this utility model, the bottom of the main pipe of the internal circulation pipe is provided with a through hole that communicates with the inner cavity of the recrystallization kettle.

[0015] The beneficial effects of this utility model are as follows:

[0016] 1. In this application, the auger shaft directly connected to the output shaft of the drive motor rotates at high speed, while the internal circulation pipe and scraper connected to the auger shaft via the planetary gear set rotate at low speed. The high-speed rotating auger shaft, in conjunction with the internal circulation pipe, achieves efficient vertical circulation of the solution. At the same time, the axial rotation of the internal circulation pipe and scraper stirs the solution, achieving horizontal circulation. This results in uniform crystal size of the generated squalene, meeting the requirements for accurate weighing of squalene. The simultaneous vertical and horizontal circulation of the solution improves the heat exchange efficiency between the temperature control tubes and reduces the recrystallization time.

[0017] Second, the rotating scraper in this application is close to the inner wall of the recrystallization vessel, which can stir up the squalene crystals deposited at the bottom of the recrystallization vessel to a certain extent, promote the squalene crystals to circulate in the solution, and make the generated squalene crystals uniform in size. Attached Figure Description

[0018] Figure 1This is a schematic diagram of the overall structure of an embodiment of the present utility model;

[0019] Figure 2 This is a schematic diagram of the structure of the temperature control tube and the solenoid three-way valve in an embodiment of this utility model;

[0020] Figure 3 This is a schematic diagram of the drive motor, planetary gear set, internal circulation pipe and scraper in an embodiment of this utility model;

[0021] Figure 4 This is a cross-sectional view of the auger shaft, inner circulation pipe, scraper, first retaining ring, second retaining ring, and sealing bearing of an embodiment of the present utility model;

[0022] Figure 5 This is a schematic diagram of the planetary gear set and auger shaft according to an embodiment of the present invention;

[0023] Figure 6 This is a cross-sectional view of the planetary carrier, gear ring, and balls in an embodiment of the present invention;

[0024] Figure 7 An exploded view of the feeding hopper and conical plug according to an embodiment of this utility model.

[0025] List of identifiers in attached diagrams:

[0026] 1. Recrystallization kettle; 2. Kettle lid; 3. Drive motor;

[0027] 4. Planetary gear set; 401. Sun gear; 402. Planet gears; 403. Planet carrier; 404. Ring gear; 405. Ball bearings;

[0028] 5. Screw shaft; 6. Internal circulation pipe; 7. Scraper; 8. First retaining ring; 9. Second retaining ring; 10. Sealed bearing; 11. Temperature control pipe; 12. Solenoid three-way valve; 13. Feed hopper; 14. Conical plug; 15. Mounting bracket. Detailed Implementation

[0029] The present invention will be further explained below with reference to the accompanying drawings and specific embodiments. It should be understood that the following specific embodiments are only used to illustrate the present invention and are not intended to limit the scope of the present invention.

[0030] Please see Figure 1-7A squalene purification and crystallization apparatus includes a recrystallization vessel 1, with a vessel cover 2 on top. The recrystallization vessel 1 and the vessel cover 2 are fixedly connected by several sets of bolts and nuts. A drive motor 3 is installed on the top of the vessel cover 2, and a planetary gear set 4 is installed on the bottom of the vessel cover 2. An auger shaft 5 is coaxially fixedly connected to the output end of the drive motor 3, and the auger shaft 5 is coaxially fixedly connected to the sun gear 401 of the planetary gear set 4. An inner circulation pipe 6 is coaxially fixedly connected to the planet carrier 403 of the planetary gear set 4, and the auger shaft 5 extends into the main pipe of the inner circulation pipe 6. The sun gear 401 meshes with several planet gears 402, and the planet gears 402 mesh with a gear ring 404 fixedly connected to the vessel cover 2. Each planet gear 402 is rotatably connected to the planet carrier 403. Branch pipes extend from the top and bottom of the inner circulation pipe 6, and each branch pipe has several through holes communicating with the inner cavity of the recrystallization vessel 1. The bottom of the main pipe of the internal circulation pipe 6 has a through hole communicating with the inner cavity of the recrystallization vessel 1 for drawing the solution from the bottom of the recrystallization vessel 1. The blades of the auger shaft 5 are mainly located between the top and bottom extensions of the internal circulation pipe 6. The internal circulation pipe 6 extends to form a scraper 7 that fits against the inner wall of the recrystallization vessel 1.

[0031] In planetary gear set 4, the diameter of planetary gear 402 is larger than that of sun gear 401, which increases the speed difference between planetary gear 402 and planet carrier 403. Ring gear 404 has an annular groove containing several balls 405 that collectively lift the planet carrier 403. Because the planet carrier 403 is lifted by the balls 405, rolling friction occurs between the planet carrier 403 and ring gear 404, preventing static friction from the planet carrier 403 directly pressing down on the ring gear 404, thus reducing the rotational resistance of the planet carrier 403.

[0032] The auger shaft 5 is fixedly fitted with a first retaining ring 8, which does not contact the inner circulation pipe 6. A second retaining ring 9 is fixedly embedded in the inner wall of the main pipe of the inner circulation pipe 6, and this second retaining ring also does not contact the auger shaft 5. Both the first retaining ring 8 and the second retaining ring 9 are positioned above the extension of the top branch pipe of the inner circulation pipe 6. A sealing bearing 10 is fixedly fitted with the auger shaft 5, and the outer ring of the sealing bearing 10 is fixedly embedded in the main pipe of the inner circulation pipe 6. The sealing bearing 10 is positioned above the first retaining ring 8 and the second retaining ring 9. During operation, the first retaining ring 8 and the second retaining ring 9 can block the upward flow of liquid driven by the auger shaft 5, reducing the direct impact on the sealing bearing 10.

[0033] The sidewall of the recrystallization vessel 1 is inlaid with a spiral temperature control tube 11, and both ends of the temperature control tube 11 are connected to an electromagnetic three-way valve 12 for switching between external hot and cold circulation pipelines. Each electromagnetic three-way valve 12 is simultaneously connected to both a hot circulation pipeline and a cold circulation pipeline. The electromagnetic three-way valve 12 is equipped with a switching switch, which can simultaneously switch both ends of the temperature control tube 11 to connect to either the hot circulation pipeline or the cold circulation pipeline.

[0034] The recrystallization vessel 1 is connected to a mounting frame 15, and the protrusions at both ends of the recrystallization vessel 1 are vertically slidably inserted into the two vertical rods of the mounting frame 15. By lifting the recrystallization vessel 1 upwards, the recrystallization vessel 1 can be detached from the mounting frame 15.

[0035] The lid 2 is equipped with a feeding hopper 13 that extends into the inner cavity of the recrystallization vessel 1, and a conical plug 14 is installed at the top opening of the feeding hopper 13.

[0036] Working principle:

[0037] In use, open the conical stopper 14 and pour an appropriate amount of anhydrous ethanol into the inner cavity of the recrystallizer 1 through the opening of the feeding hopper 13. Then, pour an appropriate amount of coarse squalene crystals into the opening of the feeding hopper 13 (if there are crystal residues in the feeding hopper 13, some anhydrous ethanol can be reserved beforehand for rinsing). Next, the electromagnetic three-way valve 12 simultaneously switches both ends of the temperature control tube 11 to connect to the hot circulation pipeline. Hot circulating water is then introduced into the temperature control tube 11 to heat the solution in the recrystallizer 1 to 78°C to create a saturated hot solution, completely dissolving the squalene. During the dissolution process of crude heparin crystals, the drive motor 3 drives the auger shaft 5 to rotate. The rotating auger shaft 5 draws up the solution from the bottom of the recrystallization vessel 1 through the inner circulation pipe 6. Then, the drawn-up solution is sprayed out through the top branch pipe through the through hole of the inner circulation pipe 6, thus forming an up-and-down circulation of the solution in the recrystallization vessel 1. At the same time, the auger shaft 5 drives the planetary carrier 403 to rotate at low speed through the sun gear 401, planet gear 402 and gear ring 404, so that the inner circulation pipe 6 and scraper 7 rotate at low speed to stir the solution laterally, so that the solution heats up rapidly.

[0038] During recrystallization, the electromagnetic three-way valve 12 simultaneously switches both ends of the temperature control tube 11 to connect to the cold circulation pipeline. Cold circulating water is introduced into the temperature control tube 11 to cool the solution in the recrystallization vessel 1 to 4°C. During cooling, the auger shaft 5 and the inner circulation pipe 6 work together to circulate the solution in the recrystallization vessel 1 vertically. At the same time, the inner circulation pipe 6 and the scraper 7 rotate at low speed to stir the solution horizontally, causing the solution to cool down rapidly. During the cooling process, the solubility of squalene crystals in the saturated solution gradually decreases, and fine crystals gradually precipitate. The low-speed rotating scraper 7 can also stir up the deposited fine crystals, so that the precipitated crystals circulate vertically and horizontally in the recrystallization vessel 1, resulting in uniform crystal size. Because the solution is undergoing relatively intense circulation and stirring when the crystals precipitate, the generated crystals are all small individuals (the volume of a single crystal is much smaller than the size of the through hole in the inner circulation pipe 6, which does not affect the solution circulation).

[0039] After recrystallization is complete, open the conical stopper 14 and the stopcock at the bottom of the recrystallization vessel 1 to quickly release the solid-liquid mixture and filter out fine sand-like crystals.

[0040] It should be noted that the above content merely illustrates the technical concept of this utility model and cannot be used to limit the scope of protection of this utility model. For those skilled in the art, several improvements and modifications can be made without departing from the principle of this utility model, and all such improvements and modifications fall within the scope of protection of the claims of this utility model.

Claims

1. A squalene purification and crystallization apparatus, comprising a recrystallization vessel (1), characterized in that, The recrystallization vessel (1) is covered with a lid (2). A drive motor (3) is installed on the top of the lid (2), and a planetary gear set (4) is installed at the bottom of the lid (2). An auger shaft (5) is coaxially fixedly connected to the output end of the drive motor (3), and the auger shaft (5) is coaxially fixedly connected to the sun gear (401) of the planetary gear set (4). An inner circulation pipe (6) is coaxially fixedly connected to the planet carrier (403) of the planetary gear set (4), and the auger shaft (5) extends into the main shaft of the inner circulation pipe (6). In the tube, the sun gear (401) meshes with several planet gears (402), and the planet gears (402) mesh with a gear ring (404) that is fixedly connected to the lid (2). Each planet gear (402) is rotatably connected to the planet carrier (403). The top and bottom of the inner circulation tube (6) extend out of the branch tube, and each branch tube has several through holes that communicate with the inner cavity of the recrystallization vessel (1). The inner circulation tube (6) extends out of the scraper (7) that fits against the inner wall of the recrystallization vessel (1).

2. The shark liver alcohol purification and crystallization apparatus according to claim 1, characterized in that, The diameter of the planetary gear (402) is larger than the diameter of the sun gear (401).

3. The shark liver alcohol purification and crystallization apparatus according to claim 1, characterized in that, The gear ring (404) is provided with an annular groove, and a number of balls (405) are placed in the annular groove to jointly lift the planet carrier (403).

4. The shark liver alcohol purification and crystallization apparatus according to claim 1, characterized in that, The auger shaft (5) is fixedly fitted with a first retaining ring (8), and the first retaining ring (8) does not contact the inner circulation pipe (6). The inner wall of the main pipe of the inner circulation pipe (6) is fixedly inlaid with a second retaining ring (9), and the second retaining ring (9) does not contact the auger shaft (5). The first retaining ring (8) and the second retaining ring (9) are both located above the extension of the top branch pipe of the inner circulation pipe (6).

5. The shark liver alcohol purification and crystallization apparatus according to claim 4, characterized in that, The auger shaft (5) is fixedly fitted with a sealed bearing (10), and the outer ring of the sealed bearing (10) is fixedly embedded in the main pipe of the inner circulation pipe (6). The sealed bearing (10) is positioned above the first retaining ring (8) and the second retaining ring (9).

6. The shark liver alcohol purification and crystallization apparatus according to claim 1, characterized in that, The side wall of the recrystallization vessel (1) is inlaid with a spiral temperature control tube (11), and both ends of the temperature control tube (11) are connected to an electromagnetic three-way valve (12) for switching the external hot and cold circulation pipeline.

7. The squalene purification and crystallization apparatus according to claim 1, characterized in that, The recrystallization vessel (1) is connected to a mounting frame (15), and the protrusions at both ends of the recrystallization vessel (1) are vertically slidably inserted into the two vertical rods of the mounting frame (15).

8. The squalene purification and crystallization apparatus according to claim 1, characterized in that, The bottom of the main pipe of the internal circulation pipe (6) is provided with a through hole that communicates with the inner cavity of the recrystallization kettle (1).

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