A pressure reduction filter membrane package for enlarging a liquid inlet hole

Abstract

This utility model discloses a pressure-reducing filter membrane pack with enlarged inlet holes, including an inlet permeation layer to facilitate the spread of the drug solution along the cross-section, a filtrate permeation layer to facilitate the passage of the filtered drug solution, an edge-sealing adhesive, a pore-sealing adhesive, a filter membrane, and a raised silicone ring to seal the inlet holes of the filter membrane. Both the inlet permeation layer and the filtrate permeation layer are provided with inlet holes, outlet holes, and filtrate holes for receiving the filtered filtrate. The filter membrane is also provided with inlet holes, outlet holes, and filtrate holes. The inlet permeation layer is provided with pore-sealing adhesive around the filtrate holes, and the filtrate permeation layer is provided with pore-sealing adhesive around the inlet holes and outlet holes. The raised silicone ring is located around the inlet holes of the filtrate permeation layer and seals the outer ring of the inlet holes of the filtrate permeation layer with a diameter larger than that of the inlet holes of the inlet permeation layer. This pressure-reducing filter membrane pack can significantly increase the inlet volume, achieve pressure-reducing filtration, and has a significant effect. At the same time, the structural change of the inlet filter holes can reduce the pump speed required for filtration, reduce power consumption, and save costs.

Description

Technical Field

[0001] This utility model relates to the field of filtration equipment technology, specifically to a pressure-reducing filter membrane pack with enlarged liquid inlet holes. Background Technology

[0002] In the current biopharmaceutical field, filtration membrane packs are frequently used. Specialized membrane clamping devices are employed to hold and position the membrane packs, and high-pressure pharmaceutical solutions are pumped into them through the inlet line. The solutions are then spread out and thoroughly filtered through multiple parallel tangential flow channel membranes within the membrane pack. Unfiltered solutions are then returned from the outlet to the pharmaceutical container, and continuously circulated back into the membrane pack for further filtration and concentration. However, existing membrane clamping devices have relatively standardized specifications, with strict limitations on the diameter of the inlet orifice. (See [reference needed]). Figure 1 The inlet and filter holes are typically arranged adjacently and alternately, which limits the size of the inlet hole, thus affecting the diameter of the filter hole. To increase the inlet flow rate, if the inlet diameter can be increased without replacing the membrane clamp and maintaining the same inlet hydraulic pressure, pressure drop filtration of the pharmaceutical solution entering the membrane pack can be achieved. This significantly reduces the hydraulic pressure of the high-pressure pharmaceutical solution within the filter membrane pack, increasing the filtration flow rate and reducing the risk of the high-pressure pharmaceutical solution breaching the filter membrane pack's seal, effectively preventing leakage. Utility Model Content

[0003] The purpose of this invention is to meet the technical requirement of increasing the inlet diameter to achieve pressure drop filtration of the drug solution entering the membrane pack without changing the membrane clamp and keeping the inlet pressure unchanged. We need to design a pressure-reducing filtration membrane pack with enlarged inlet holes.

[0004] The technical solution adopted to solve the above problems is:

[0005] A pressure-reducing filter membrane package with enlarged inlet holes includes an inlet permeation layer that facilitates the spread of the drug solution along a cross-section, a filtrate permeation layer that allows the filtered drug solution to pass through, an edge-sealing adhesive, a perforation adhesive for sealing the inlet hole, outlet hole, and filtrate hole, a filter membrane, and a raised silicone ring for sealing the inlet hole of the filter membrane.

[0006] Both the inlet permeation layer and the filtrate permeation layer are provided with inlet holes, outlet holes, and filtrate holes for receiving the filtered filtrate. The filter membrane is also provided with inlet holes, outlet holes, and filtrate holes. The inlet holes, outlet holes, and filtrate holes of the alternatingly stacked inlet permeation layer, filter membrane, and filtrate permeation layer are aligned vertically and injection molded to form a membrane package.

[0007] The inlet permeation layer has a pore-sealing adhesive around the filtrate holes, and the filtrate permeation layer has pore-sealing adhesive at both the inlet and outlet holes. This allows the high-pressure liquid pumped into the filter membrane structure to spread only on the surface of the inlet permeation layer after entering the inlet hole, and then pass through the filter membrane under hydraulic pressure for filtration. The filtered liquid spreads in the filtrate permeation layer and flows out through the filtrate holes, while the liquid that does not pass through the filter membrane flows to the outlet hole and back into the liquid to be filtered.

[0008] The raised silicone ring is disposed on the outer ring of the inlet hole of the filtrate permeation layer, and blocks the outer ring of the inlet hole of the filtrate permeation layer with a diameter larger than that of the inlet hole of the filtrate permeation layer.

[0009] Furthermore, the raised silicone ring has a T-shaped vertical cross-section, including a boss ring that blocks the liquid inlet hole of the filter membrane and a pressing edge that blocks the liquid inlet hole of the filtrate permeation layer. This makes the actual liquid inlet diameter of the entire filter membrane pack calculated based on the inner diameter of the raised silicone ring. This design will make the actual liquid inlet diameter larger than the liquid inlet diameter of the liquid permeation layer, thereby increasing the liquid inlet volume.

[0010] Furthermore, the inlet port is connected to the high-pressure drug solution pipeline to be filtered, and the outlet port is connected to the unfiltered concentrated drug solution pipeline, so as to discharge the unfiltered concentrated drug solution from the filter structure and release the pressure therein.

[0011] Furthermore, this filter membrane pack is pressed using a special molding clamp, and its outer periphery is sealed with edge-sealing adhesive and silicone.

[0012] The beneficial effects of this utility model are:

[0013] The pressure-reducing filter membrane pack with enlarged inlet holes retains the original inlet hole structure of the inlet permeate layer and filtrate permeate layer. It only enlarges the inlet hole of the filtrate permeate layer that was previously blocked. The pore size of the inlet permeate layer is relatively infinite, but it can still be used with the original filter membrane clamp equipment. The overall pore size of the inlet holes is limited by the pore size of the blocked inlet holes of the filtrate permeate layer. Therefore, after enlarging the blocked pore size, the inlet volume can be significantly increased, achieving pressure-reducing filtration with obvious effect. At the same time, the change in the structure of the inlet filter holes can reduce the pump speed required for filtration, reduce power consumption, and save costs. Attached Figure Description

[0014] Figure 1 An exploded view of the pressure-reducing filter membrane pack with enlarged inlet holes, as shown in the embodiment.

[0015] Figure 2 This is a front view of the liquid inlet permeation layer described in the embodiment;

[0016] Figure 3 This is a front view of the filtrate permeation layer described in the embodiment;

[0017] Figure 4 This is a front view of the filter membrane described in the embodiment;

[0018] Figure 5 This is a partial enlarged view of the inlet hole of the filtrate permeation layer described in the embodiment;

[0019] Figure 6 A cross-sectional view of the pressure-reducing filter membrane pack with enlarged inlet port, as shown in the embodiment;

[0020] Among them, 1-liquid inlet permeation layer, 2-filter membrane, 3-filtrate permeation layer, 4-edge binding adhesive, 5-liquid inlet hole, 6-filtrate hole, 7-hole binding adhesive, 8-limiting groove, 9-outer ring of boss ring, 10-boss ring, 11-pressing edge binding, 12-outer ring of liquid inlet hole, 13-liquid inlet, 14-filtrate inlet, 15-actual diameter of liquid inlet hole. Detailed Implementation

[0021] The technical solution of this utility model will be clearly and completely described below with reference to the accompanying drawings and by way of embodiments.

[0022] Example :

[0023] Please see Figures 1 to 4 This embodiment proposes a filter membrane packing structure with an enlarged inlet, including an inlet permeation layer 1 that facilitates the spread of the drug solution along the cut surface, a filtrate permeation layer 3 that allows the filtered drug solution to pass through, an edge-sealing adhesive 4, a pore-sealing adhesive 7 for sealing the inlet hole 5, the outlet hole (not shown in the figure), and the filtrate hole 6, a filter membrane 2, and a raised silicone ring for sealing the inlet hole of the filter membrane 8.

[0024] Among them: See Figure 1 and Figure 2 The liquid inlet permeation layer 2 and the liquid outlet permeation layer 1 are both provided with liquid inlet holes 5, liquid outlet holes (not shown in the figure) and liquid outlet holes 6 for receiving the filtered liquid. The filter membrane 8 is also provided with liquid inlet holes 5, liquid outlet holes (not shown in the figure) and liquid outlet holes 6. The liquid inlet holes, liquid outlet holes and liquid outlet holes of the liquid inlet permeation layer 2, filter membrane 8 and liquid outlet permeation layer 1 are aligned vertically and vertically. After injection molding to form a membrane package, it is pressed with a special molding fixture, and the outer periphery is sealed with edge-sealing adhesive 4 and silicone.

[0025] See Figure 5 The inlet permeation layer 2 has a pore-sealing adhesive 7 on the outer periphery of the filtrate holes, and the filtrate permeation layer 1 has a pore-sealing adhesive 7 on the inlet and outlet holes, so that after the high-pressure liquid with the filter membrane 8 encapsulation structure is pumped into the inlet 13, it can only spread on the surface of the inlet permeation layer 2, and then pass through the filter membrane 8 under hydraulic action to perform filtration. The filtered liquid spreads in the filtrate permeation layer 1 and converges to the filtrate outlet 14 to flow out, while the liquid that has not passed through the filter membrane 8 flows to the outlet hole and flows back into the liquid to be filtered.

[0026] See Figure 5 and Figure 6 The raised silicone ring is disposed on the outer ring of the inlet hole of the filtrate permeation layer 1, and blocks the outer ring of the inlet hole of the filtrate permeation layer with a diameter larger than that of the inlet hole of the inlet permeation layer 2.

[0027] Further implementation plans are as follows, see [link / reference] Figure 5 The raised silicone ring has a T-shaped vertical cross-section and includes a boss ring 10 that blocks the liquid inlet hole of the filter membrane and a pressing edge 13 that blocks the liquid inlet hole of the filtrate permeation layer. This makes the actual liquid inlet hole diameter of the entire filter membrane package calculated based on the inner hole diameter of the raised silicone ring. This design makes the actual liquid inlet hole diameter 15 larger than the liquid inlet hole diameter of the liquid permeation layer 2, increasing the liquid inlet volume. After enlarging the blocking hole diameter, the liquid inlet volume can be significantly increased, achieving pressure reduction filtration with obvious effect. At the same time, the change in the structure of the liquid inlet filter hole can reduce the pump speed required for filtration, reduce power consumption, and save costs.

[0028] A further implementation is that the inlet port is connected to the high-pressure drug solution pipeline to be filtered, and the outlet port is connected to the unfiltered concentrated drug solution pipeline, so as to discharge the unfiltered concentrated drug solution from the filter structure and release the pressure therein.

[0029] The embodiments of the present invention have been described in detail above with reference to the accompanying drawings. However, the present invention is not limited to the above embodiments. Within the scope of knowledge possessed by those skilled in the art, various changes, modifications, substitutions and variations can be made without departing from the spirit of the present invention. The scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A pressure-reducing filter membrane pack with enlarged inlet orifice, comprising an inlet permeation layer for facilitating the spread of the drug solution along a cross-section, a filtrate permeation layer for allowing the filtered drug solution to pass through, an edge-sealing adhesive, a sealing adhesive for sealing the inlet orifice, an outlet or filtrate orifice, a filter membrane, and a raised silicone ring for sealing the inlet orifice of the filter membrane, characterized in that: Both the inlet permeation layer and the filtrate permeation layer are provided with inlet holes, outlet holes, and filtrate holes for receiving the filtered filtrate. The filter membrane is also provided with inlet holes, outlet holes, and filtrate holes. The inlet holes, outlet holes, and filtrate holes of the alternatingly stacked inlet permeation layer, filter membrane, and filtrate permeation layer are aligned vertically and injection molded to form a membrane package. The inlet permeation layer has a pore-sealing adhesive on the outer periphery of the filtrate pores, and the filtrate permeation layer has pore-sealing adhesive on the inlet and outlet pores. The raised silicone ring is disposed on the outer ring of the inlet hole of the filtrate permeation layer, and blocks the outer ring of the inlet hole of the filtrate permeation layer with a diameter larger than that of the inlet hole of the filtrate permeation layer.

2. The pressure-reducing filter membrane pack with enlarged inlet orifice according to claim 1, characterized in that: The raised silicone ring has a T-shaped vertical cross-section and includes a boss ring that blocks the liquid inlet of the filter membrane and a pressing edge that blocks the liquid inlet of the filtrate permeation layer.

3. The pressure-reducing filter membrane pack with enlarged inlet orifice according to claim 1, characterized in that: The filter membrane pack is pressed together using a special molding fixture, and its outer periphery is sealed with edge-sealing adhesive and silicone.

4. The pressure-reducing filter membrane pack with enlarged inlet hole according to claim 1, characterized in that: The inlet is connected to the high-pressure liquid to be filtered pipeline, and the outlet is connected to the unfiltered concentrated liquid pipeline.

5. The pressure-reducing filter membrane pack with enlarged inlet orifice according to claim 1, characterized in that: The high-pressure liquid medicine pumped into the filter membrane package enters the inlet hole and spreads on the surface of the inlet permeation layer. Then, under the action of hydraulic pressure, it passes through the filter membrane to perform filtration. The filtered liquid medicine spreads in the filtrate permeation layer and flows out through the filtrate hole. The liquid medicine that does not pass through the filter membrane flows to the outlet hole and flows back into the liquid medicine to be filtered.

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