A sterile cold chain product weighing and dispensing apparatus

Abstract

The utility model discloses a kind of sterile cold chain product's weighing and subpackaging equipment, including equipment cabinet and circuit control system;The equipment cabinet includes weighing module, purification module and temperature control module, and it is connected between respectively with circuit control system by data line;The weighing module includes weighing table, weighing sensor, display screen, blanking valve, breathable material cover, material import and export and isolation glove;The purification module includes air inlet, filter, fan, anemometer, through-wall bushing and air outlet;The temperature control module includes refrigerator and temperature sensor.The weighing module can also include material conveying device, and the material conveying device includes material pipe, hopper and vibration valve.The weighing and subpackaging equipment of the utility model is easy to operate, weighing precision is high, can provide required low temperature and sterile environment for sterile cold chain product, ensure the quality of product, and weighing and subpackaging efficiency is high, conducive to industrial application.

Description

Technical Field

[0001] This utility model belongs to the field of weighing and dispensing technology, specifically relating to a weighing and dispensing device for aseptic cold chain products. Background Technology

[0002] Aseptic cold chain products (such as insulin, blood products, freeze-dried products, vaccines, and other biological products) must meet aseptic and cold chain conditions during production, packaging, storage, and transportation to maintain their physicochemical stability and prevent microbial contamination. Among these, the weighing and dispensing process is crucial to product quality. The operational accuracy of the equipment and environmental conditions (such as temperature and cleanliness) directly affect the product's weighing accuracy, physicochemical properties, safety, and efficacy.

[0003] Currently, common weighing and dispensing equipment on the market mainly includes fan filter units (FFUs), clean benches, and restricted access barrier systems (RABS). In addition, patent document CN212963604U discloses a biochemical reagent weighing device, which, through the cooperation of drying devices, sterilization devices, and refrigeration units, precisely controls the temperature, humidity, and air quality within a protective chamber to ensure a stable weighing environment, improve weighing accuracy, and effectively protect the reagents from external environmental influences and prevent reagent damage through the protective chamber and sterilization device. However, these devices all have the following problems: First, the weighing and dispensing process requires manual operation and cannot be automated, resulting in low weighing accuracy and efficiency; second, lightweight products are easily affected by airflow and float, interfering with weighing and causing quality loss; third, existing equipment cannot meet the low-temperature requirements of aseptic cold chain products, requiring multiple temperature controls during weighing and dispensing, prolonging operation time and easily leading to a decline in the product's physicochemical properties.

[0004] Therefore, there is an urgent need to develop a new type of weighing and dispensing equipment that can simultaneously achieve both low temperature and aseptic control, and ensure weighing accuracy and stability, in order to meet the production needs of aseptic cold chain products. Utility Model Content

[0005] To overcome the shortcomings of the prior art, this utility model provides a weighing and dispensing device for aseptic cold chain products, including a device housing and a circuit control system; the device housing includes a weighing module, a purification module, and a temperature control module, which are respectively connected to the circuit control system via data cables; the weighing module includes a weighing platform, a weighing sensor, a display screen, a feeding valve, a breathable material cover, a material inlet and outlet, and isolation gloves; the purification module includes an air inlet, a filter, a fan, an anemometer, a wall-penetrating sleeve, and an air outlet; the temperature control module includes a cooler and a temperature sensor.

[0006] Furthermore, the circuit control system is used to control the opening and closing of the devices in the weighing module, purification module and temperature control module to realize the automated operation of the equipment (such as automatic feeding, automatic weighing, automatic temperature control, automatic purification and automatic loading).

[0007] Furthermore, the weighing platform is located on top of the weighing sensor and is used to place the material being weighed.

[0008] Furthermore, the weighing sensor is located at the bottom of the equipment housing and is used to measure the weight of the material.

[0009] Furthermore, the weighing sensor is connected to the circuit control system via a data line and transmits electrical signals to feed back the detected weight data to the circuit control system.

[0010] Furthermore, the display screen is connected to the weighing sensor via a data cable and transmits the weight data detected by the weighing sensor to the display screen in real time through electrical signal transmission, so as to provide accurate weighing results.

[0011] Furthermore, the display screen is located inside or outside the equipment housing. Specifically, the display screen is located anywhere inside the equipment housing that is convenient for the operator to see (such as the bottom of the equipment housing or the surface of the weighing sensor).

[0012] Furthermore, the discharge valve is located directly above the weighing platform. Specifically, the discharge valve is also fixed to the side of the equipment housing via a connector.

[0013] Furthermore, the discharge valve is used to temporarily store materials and guide them onto the weighing platform. Specifically, the valve chamber of the discharge valve is used to temporarily store the materials to be weighed; after the valve is opened, the materials are discharged onto the weighing platform. More specifically, the discharge valve can control the material discharge speed.

[0014] Furthermore, the feeding valve is an electromagnetic feeding valve or a star-shaped feeding valve.

[0015] Furthermore, the feeding valve is connected to the circuit control system via a data cable, and the circuit control system is used to control the opening and closing of the feeding valve. Specifically, after the circuit control system receives material weight data fed back by the weighing sensor and finds that the material weight has reached the set dispensing weight, the circuit control system controls the feeding valve to close and stop feeding.

[0016] Furthermore, the valve chamber and valve port of the feeding valve are made of anti-static material to prevent material adsorption.

[0017] Furthermore, the breathable material cover is provided with multiple air vents.

[0018] Furthermore, the breathable material cover is used to cover the discharge valve or discharge hopper so as to allow Class A air supply to pass through during the discharge process, thereby protecting the material and preventing material backflow.

[0019] Furthermore, the material inlet and outlet are located on the side of the equipment housing.

[0020] Furthermore, the material inlet / outlet is connected to the circuit control system via a data cable, and the circuit control system is used to control the opening and closing of the material inlet / outlet.

[0021] Furthermore, the isolation gloves are located on the front of the equipment housing. Specifically, the isolation gloves are fixed to the front of the equipment housing via connectors. Operators can use the isolation gloves to move materials and their dispensing containers placed inside the equipment housing.

[0022] Furthermore, the number of isolation gloves is one pair.

[0023] Furthermore, the weighing module also includes a material conveying device for automatically feeding the equipment.

[0024] Furthermore, the material conveying device includes a material pipe, a hopper, and a vibrating valve.

[0025] Furthermore, one end of the material pipe is fixed to the side of the equipment housing, and the other end is fixed to the top of the discharge valve, wherein the end connected to the side of the equipment housing is higher than the end connected to the top of the discharge valve. The material pipe is inclined.

[0026] Furthermore, the material pipe has a hollow structure, which is used to temporarily store the material to be weighed and to guide the material downward to the discharge valve.

[0027] Furthermore, the hopper is fixed above the material pipe and communicates with the inside of the material pipe to guide the material to be weighed into the material pipe.

[0028] Furthermore, the hopper is made of an anti-static material to prevent material adsorption.

[0029] Furthermore, the vibration valve is fixed to the outer wall of the material pipe. Specifically, the vibration valve is located at any position on the outer wall of the material pipe (such as the end near the discharge valve, the end near the side of the equipment housing, or the middle area).

[0030] Furthermore, the vibration valve is connected to the circuit control system via a data cable, and the circuit control system is used to control the opening and closing of the vibration valve. Specifically, the circuit control system controls the vibration valve to open, and the vibration of the vibration valve causes the material to be conveyed downward along the material pipe to the discharge valve.

[0031] Furthermore, the air inlet is located at the top of the equipment housing to guide the gas to flow vertically downwards. This equipment employs a vertically downward, unidirectional laminar flow air intake method, ensuring a smooth airflow from top to bottom and thus preventing material from being disturbed by lateral turbulence.

[0032] Furthermore, the filter is located below the air inlet. Specifically, the filter is also fixed to the four sides of the equipment housing via connectors.

[0033] Furthermore, the filter is a high-efficiency filter, such as an H14, H15, or H16 class high-efficiency filter. Specifically, the filter has a filtration efficiency of ≥99.999% for 0.3μm particles.

[0034] Furthermore, the filter is used to filter particulate matter in the air, thereby achieving Class A air supply and ensuring that the internal environment of the equipment enclosure reaches Class A cleanliness.

[0035] Furthermore, the fan is located below the filter. Specifically, the filter is fixed to the back of the equipment housing via a connector.

[0036] Furthermore, the fan is used to deliver air (such as indoor air) into the equipment enclosure.

[0037] Furthermore, the fan and the circuit control system are connected via a data cable, and the circuit control system is used to control the opening and closing of the fan.

[0038] Furthermore, the anemometer is located below the filter. Specifically, the anemometer is also fixed to the side of the equipment housing via a connector. More specifically, the anemometer is located between the filter and the discharge valve, and the distance between the anemometer and the filter is 15-20cm, specifically 15, 16, 17, 18, 19, or 20cm.

[0039] Furthermore, the anemometer is used to measure wind speed. Specifically, the wind speed measured by the anemometer (inside the equipment housing) is 0.36-0.54 m / s, such as 0.36, 0.37, 0.38, 0.39, 0.4, 0.45, 0.5, 0.52, and 0.54 m / s.

[0040] Furthermore, the through-wall sleeve is located on the side of the equipment housing and is lower than the horizontal position of the filter. It is used to connect to disinfection equipment (such as VHP generator, formaldehyde generator, etc.) outside the equipment housing to purify the internal environment of the equipment housing.

[0041] Furthermore, the air outlet is located at the bottom of the four sides of the equipment housing, and is used to exhaust the gas inside the equipment housing.

[0042] Furthermore, the air outlet adopts a perforated plate structure.

[0043] Furthermore, the weighing platform is located in the area of ​​most stable airflow below the air inlet and is far from the air outlet.

[0044] Furthermore, the cooler is located between the air inlet and the filter. Specifically, the cooler is also fixed to the sides or back of the equipment housing via connectors.

[0045] Furthermore, the refrigeration unit employs mechanical refrigeration (compressor and refrigerant) or cold water circulation refrigeration to maintain the temperature inside the equipment housing within a set low temperature range, ensuring that the material remains at a low temperature throughout the weighing and dispensing process.

[0046] Furthermore, the cooler adopts a cooling coil structure.

[0047] Furthermore, the cooler is connected to the circuit control system via a data cable, and the circuit control system is used to control the opening and closing of the cooler.

[0048] Furthermore, the temperature sensor is located below the cooler. Specifically, the temperature sensor is also fixed to the side of the equipment housing via a connector. More specifically, the temperature sensor is located between the filter and the discharge valve.

[0049] Furthermore, the temperature sensor is used to detect the temperature inside the equipment enclosure in real time. Specifically, the temperature of the temperature sensor (inside the equipment enclosure) is 0-15℃, such as 0, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15℃, preferably 0-10℃, and more preferably 2-10℃.

[0050] Furthermore, the temperature sensor is connected to the circuit control system via a data line and transmits electrical signals to feed back the real-time detected temperature data to the circuit control system, thereby achieving automatic temperature regulation.

[0051] Furthermore, the equipment enclosure is made of stainless steel to ensure the equipment's corrosion resistance and thermal insulation performance.

[0052] Furthermore, the sterile cold chain products include, but are not limited to, vaccines, biological products (such as insulin, blood products, freeze-dried biological products, etc.), injectable solutions, and sterile dressings.

[0053] Preferably, the aseptic cold chain product is a biological freeze-dried product, such as biological freeze-dried powder, biological freeze-dried granules, biological freeze-dried microspheres, etc.

[0054] More preferably, the aseptic cold chain product is a collagenase freeze-dried product, such as collagenase freeze-dried powder, collagenase freeze-dried granules, collagenase freeze-dried microspheres, etc.

[0055] This utility model has the following beneficial effects:

[0056] (1) The weighing and dispensing equipment of this utility model achieves dual control of low temperature and sterility by configuring a temperature control system and a purification system, effectively avoiding the decline of physical and chemical indicators of sterile cold chain products due to temperature changes and microbial contamination due to imperfect isolation function, meeting the dual requirements of sterile cold chain products for low temperature and sterility conditions, thereby greatly improving work efficiency.

[0057] (2) The weighing and dispensing equipment of this utility model effectively solves the problem of quality loss caused by product floating during dispensing and transfer by optimizing the airflow direction, using anti-static materials, and designing a breathable material cover. Specifically, the equipment adopts a vertically downward unidirectional laminar flow design, allowing the airflow to flow smoothly from top to bottom, and placing the weighing platform in the most stable position of the airflow, away from the air outlet, thereby avoiding lateral turbulence interference and stabilizing the weighing environment. At the same time, the device that directly contacts the product uses anti-static materials (conductive plastic), effectively eliminating the scattering phenomenon caused by electrostatic adsorption. In addition, the equipment is also equipped with a breathable material cover, which can be covered during weighing to allow Class A air supply to pass through during material unloading, thereby protecting the material and preventing material backlash, further stabilizing the weighing environment. Through the above innovative design, this utility model significantly improves the weighing accuracy and stability.

[0058] (3) The weighing and dispensing equipment of this utility model, through the cooperation of the circuit control system and the device within the weighing module, controls the opening and closing of the dispensing valve through electrical signal transmission after setting the dispensing weight, and performs batch and weight-based dispensing. When the material reaches the required dispensing weight, the weighing sensor provides data feedback and stops dispensing, thereby realizing the automated operation of automatic dispensing and automatic weighing, which greatly improves the convenience of operation and work efficiency. In addition, the equipment can also be equipped with a material conveying device, and through the circuit control system, the vibration valve is controlled to vibrate, causing the material to be conveyed downward along the material pipe to the dispensing valve, thereby realizing the automatic feeding operation.

[0059] (4) The main body of the weighing and dispensing equipment of this utility model is made of stainless steel, which ensures the corrosion resistance and heat preservation performance of the equipment.

[0060] (5) The weighing and dispensing equipment of this utility model is easy to operate and has high weighing accuracy. It can provide the required low temperature and sterile environment for aseptic cold chain products, ensuring product quality. Moreover, the weighing and dispensing efficiency is high, which is conducive to industrial application. In addition, the equipment can dispense multiple batches of products of the same or different specifications at one time according to dispensing needs. Attached Figure Description

[0061] Figure 1 The diagram shown is a frame diagram of the weighing and dispensing equipment of Example 1.

[0062] Figure 2 The figure shown is an overall schematic diagram of the weighing and dispensing equipment of Example 1.

[0063] Figure 3 The figure shown is a cross-sectional view of the weighing and dispensing equipment of Example 1.

[0064] Figure 4 The diagram shown is a frame diagram of the weighing and dispensing equipment of Example 2.

[0065] Figure 5 The figure shown is an overall schematic diagram of the weighing and dispensing equipment of Example 2.

[0066] Figure 6 The figure shown is a cross-sectional view of the weighing and dispensing equipment of Example 2.

[0067] Figure 7 The image shown is a top view of the weighing and dispensing equipment of this utility model.

[0068] Figure 8 The image shown is a left view of the weighing and dispensing equipment of this utility model.

[0069] The annotations in the attached figures are explained as follows:

[0070] → indicates a data cable connection.

[0071] Equipment housing 1; circuit control system 2; weighing module 10; purification module 20; temperature control module 30; weighing platform 11; weighing sensor 12; display screen 13; feeding valve 14; breathable material cover 15; material inlet / outlet 16; isolation gloves 17; material conveying device 18; material pipe 181; feeding hopper 182; vibration valve 183; air inlet 21; filter 22; fan 23; anemometer 24; wall sleeve 25; air outlet 26; cooler 31; temperature sensor 32. Detailed Implementation

[0072] To make the objectives, technical solutions, and advantages of this utility model clearer, the present utility model will be further described in detail below with reference to specific embodiments and accompanying drawings. It should be understood that these descriptions are merely exemplary and not intended to limit the scope of this utility model.

[0073] In this article, the term "VHP generator" refers to an advanced space sterilization device that utilizes the highly efficient sterilization properties of hydrogen peroxide to convert liquid hydrogen peroxide into gas at room temperature. Through precise control and distribution into a specific enclosed space, it achieves highly effective killing of microbial spores, bacteria, viruses, etc.

[0074] In this document, the term "Class A" refers to a cleanliness level, defined in accordance with the relevant provisions in Appendix: Sterile Drugs of the Good Manufacturing Practice for Pharmaceuticals. Class A clean areas refer to high-risk operation areas, such as filling areas, areas where rubber stopper containers and open packaging containers that come into direct contact with sterile preparations are placed, and areas for aseptic assembly or connection operations. These areas should be maintained using unidirectional flow workbenches (hoods). The unidirectional flow system must provide uniform airflow within its working area, with an air velocity of 0.36-0.54 m / s (guideline value). The Class A air supply environment should at least meet the static requirements for Class A areas.

[0075] Example 1:

[0076] like Figure 1-3 and Figure 7-8 As shown, the aseptic cold chain product weighing and dispensing equipment of this embodiment includes an equipment housing 1 and a circuit control system 2. The equipment housing 1 includes a weighing module 10, a purification module 20 and a temperature control module 30, and they are respectively connected to the circuit control system 2 via data lines. The circuit control system 2 is used to control the opening and closing of the devices in the weighing module 10, the purification module 20 and the temperature control module 30 to realize the automated operation of the equipment.

[0077] The weighing module 10 includes a weighing platform 11, a weighing sensor 12, a display screen 13, a discharge valve 14, a breathable material cover 15, a material inlet / outlet 16, and isolation gloves 17. The weighing platform 11 is located on top of the weighing sensor 12 and is used to hold the material being weighed. The weighing sensor 12 is located at the bottom of the equipment housing 1 and is used to measure the weight of the material. The weighing sensor 12 is connected to the circuit control system 2 via a data cable and transmits the detected weight data back to the circuit control system 2 via electrical signals. The display screen 13 is connected to the weighing sensor 12 via a data cable and transmits the weight data detected by the weighing sensor 12 to the display screen 13 in real time to provide accurate weighing results. The display screen 13 is located at the bottom of the equipment housing 1. The discharge valve 14 is located directly above the weighing platform 11 and is fixed to the side of the equipment housing 1 via a connector. The valve chamber of the discharge valve 14 can temporarily store the material to be weighed; when the valve is opened, the material is discharged onto the weighing platform 11. The feeding valve 14 controls the material feeding speed. The feeding valve 14 is an electromagnetic feeding valve, connected to the circuit control system 2 via a data cable and transmitted via electrical signals. The circuit control system 2 controls the opening and closing of the valve port of the feeding valve 14. After receiving the material weight data fed back by the weighing sensor 12, and realizing that the set dispensing weight has been reached, the circuit control system 2 controls the valve port of the feeding valve 14 to close, stopping the feeding. The valve chamber and valve port of the feeding valve 14 are made of anti-static material to prevent material adsorption. The ventilated material cover 15 has multiple vent holes. The ventilated material cover 15 covers the feeding valve 14 to allow Class A airflow during the feeding process, thereby protecting the material and preventing material backflow. The material inlet / outlet 16 is located on the side of the equipment housing 1 and is connected to the circuit control system 2 via a data cable and transmitted via electrical signals. The circuit control system 2 controls the opening and closing of the material inlet / outlet 16. The isolation glove 17 is fixed to the front of the equipment housing 1 via a connector, allowing operators to move materials and their packaging containers placed inside the equipment housing using the isolation glove 17. One pair of isolation gloves 17 is used.

[0078] The purification module 20 includes an air inlet 21, a filter 22, a fan 23, an anemometer 24, a wall-penetrating sleeve 25, and an air outlet 26. The air inlet 21 is located at the top of the equipment housing 1 and guides the air to flow vertically downwards. This equipment adopts a vertically downward unidirectional laminar flow air intake method, ensuring a smooth airflow from top to bottom and avoiding interference from lateral turbulence. The filter 22 is located below the air inlet 21 and is fixed to the four sides of the equipment housing 1 via connectors. It uses H14 or higher high-efficiency filters to filter particulate matter in the air, achieving Class A air supply and ensuring that the internal environment of the equipment housing reaches Class A cleanliness. The fan 23 is located below the filter 22 and is fixed to the back of the equipment housing 1 via connectors, supplying indoor air into the equipment housing. The fan 23 is connected to the circuit control system 2 via a data cable and transmits electrical signals; the circuit control system 2 can control the opening and closing of the fan 23. An anemometer 24 is located between the filter 22 and the discharge valve 14, and is fixed to the side of the equipment housing 1 via a connector, for measuring wind speed. The distance between the anemometer 24 and the filter 22 is 15-20 cm. A through-wall sleeve 25 is located on the side of the equipment housing 1, below the level of the filter 22, for connecting to external disinfection equipment (such as a VHP generator or formaldehyde generator) to purify the internal environment of the equipment housing. Air outlets 26 are located at the bottom of the four sides of the equipment housing 1, for expelling gases from inside the equipment housing. Air outlets 26 have a perforated plate structure. Furthermore, the weighing platform 11 is located below the air inlet 21 in the area of ​​most stable airflow, and is far from the air outlet 26.

[0079] The temperature control module 30 includes a cooler 31 and a temperature sensor 32. The cooler 31 is located between the air inlet 21 and the filter 22, and is fixed to both sides of the equipment housing 1 via connectors. It can achieve cooling through mechanical refrigeration (compressor and refrigerant) or cold water circulation, thereby maintaining the internal temperature of the equipment housing within a set low-temperature range to ensure the material remains at a low temperature throughout the weighing and dispensing process. The cooler 31 employs a refrigeration coil structure. The cooler 31 is connected to the circuit control system 2 via a data cable and transmits electrical signals. The circuit control system 2 can control the opening and closing of the cooler 31. The temperature sensor 32 is located between the filter 22 and the discharge valve 14, and is fixed to the side of the equipment housing 1 via connectors. It is used to monitor the internal temperature of the equipment housing in real time. The temperature sensor 32 is connected to the circuit control system 2 via a data cable and transmits electrical signals, feeding back the detected temperature data to the circuit control system 2 to achieve automatic temperature adjustment.

[0080] The equipment housing 1 is made of stainless steel to ensure the equipment's corrosion resistance and heat insulation performance.

[0081] The weighing and dispensing equipment in this embodiment operates as follows:

[0082] (1) Before use, the operator connects the disinfection equipment (VHP generator or formaldehyde generator) to the equipment box 1 through the wall sleeve 25 and sterilizes the inside of the equipment box 1.

[0083] (2) Turn on the cooler 31 and set the temperature to 2-10℃. Then turn on the fan 23 to deliver indoor air into the equipment housing 1. The airflow passes through the air inlet 21, cooler 31 and filter 22 from top to bottom, and continues to self-clean for 30 minutes to bring the environment inside the equipment housing 1 to Class A cleanliness. Afterward, remove the outer packaging of the materials to be weighed and packaged and the packaging containers from the outside of the equipment housing 1 and wipe them with disinfectant.

[0084] (3) Open the material inlet / outlet 16, place the material and the dispensing container inside the equipment housing, and then close the material inlet / outlet 16. The operator uses isolation gloves 17 and tweezers to place the dispensing container on the weighing platform 11, and uses a medicine spoon to add the material into the valve chamber of the discharge valve 14, and then uses a breathable material cover 15 to cover the discharge valve 14.

[0085] (4) After setting the required dispensing weight in the circuit control system 2, the operator clicks the feeding button, and the equipment switches to feeding mode (the air velocity of the Class A air supply in feeding mode is 0.36 m / s). At this time, the valve of the feeding valve 14 opens, and the material falls into the dispensing container on the weighing platform 11. When the display screen 13 shows that the set dispensing weight has been reached, the valve of the feeding valve 14 closes, and feeding stops. After feeding is completed, the operator seals the dispensing container with isolation gloves 17 and transfers it to the material inlet / outlet 16, and then takes it out.

[0086] Example 2:

[0087] like Figure 4-6 and Figure 7-8 As shown, the aseptic cold chain product weighing and dispensing equipment in this embodiment is basically the same as that in Embodiment 1. The difference is that the weighing module 10 of the weighing and dispensing equipment in this embodiment also includes a material conveying device 18 for automatic feeding of the equipment. The material conveying device 18 includes a material pipe 181, a hopper 182, and a vibration valve 183.

[0088] One end of the material pipe 181 is fixed to the side of the equipment housing 1 via a connector, and the other end is fixed to the top of the discharge valve 14 via a connector. The end connected to the side of the equipment housing 1 is higher than the end connected to the top of the discharge valve 14, and the material pipe 181 is inclined. The material pipe 181 has a hollow structure and is used to temporarily store the material to be weighed and guide the material downwards to the discharge valve 14. The discharge hopper 182 is fixed above the material pipe 181 and communicates with the interior of the material pipe 181, used to guide the material to be weighed into the material pipe 181. The discharge hopper 182 is made of anti-static material to prevent material adsorption. The vibration valve 183 is fixed to the outer wall of the material pipe 181 via a connector and is located near the end of the discharge valve 14. The vibration valve 183 is connected to the circuit control system 2 via a data cable and transmits electrical signals. The circuit control system 2 can control the opening and closing of the vibration valve 183. The circuit control system 2 controls the opening of the vibration valve 183, and uses the vibration of the vibration valve 183 to cause the material to be conveyed downward along the material pipe 181 to the discharge valve 14.

[0089] The operating procedure for this weighing and dispensing equipment is as follows:

[0090] (1) Before use, the operator connects the disinfection equipment (VHP generator or formaldehyde generator) to the equipment box 1 through the wall sleeve 25 and sterilizes the inside of the equipment box 1.

[0091] (2) Turn on the cooler 31 and set the temperature to 2-10℃. Then turn on the fan 23 to deliver indoor air into the equipment housing 1. The airflow passes through the air inlet 21, cooler 31 and filter 22 from top to bottom, and continues to self-clean for 30 minutes to bring the environment inside the equipment housing 1 to Class A cleanliness. Afterward, remove the outer packaging of the materials to be weighed and packaged and the packaging containers from the outside of the equipment housing 1 and wipe them with disinfectant.

[0092] (3) Open the material inlet / outlet 16, place the material and dispensing container inside the equipment housing, and then close the material inlet / outlet 16. The operator, using isolation gloves 17 and tweezers, places the dispensing container on the weighing platform 11. Then, the material is added into the discharge hopper 182, and the discharge hopper 182 is covered with a breathable material cover 15. Subsequently, the vibration valve 183 is opened, and the vibration of the vibration valve 183 causes the material to be conveyed along the material pipe 181 to the discharge valve 14.

[0093] (4) After setting the required dispensing weight in the circuit control system 2, the operator clicks the feeding button, and the equipment switches to feeding mode (the air velocity of the Class A air supply in feeding mode is 0.36 m / s). At this time, the valve of the feeding valve 14 opens, and the material falls into the dispensing container on the weighing platform 11. When the display screen 13 shows that the set dispensing weight has been reached, the valve of the feeding valve 14 closes, and feeding stops. After feeding is completed, the operator seals the dispensing container with isolation gloves 17 and transfers it to the material inlet / outlet 16, and then takes it out.

[0094] Example 3:

[0095] In this embodiment, collagenase freeze-dried powder was weighed and packaged using both manual weighing and packaging methods and the weighing and packaging equipment of this utility model (provided by Example 1). The experimental data of the two batches of weighing and packaging are shown in Table 1 and Table 2.

[0096] Table 1: Comparative experimental data of weighing and dispensing

[0097] Weighing and dispensing time It took 2 hours and 10 minutes. It took 15 minutes. Weigh the portion of the product. 88.4g 88.4g The potency of the product after weighing 304.6 U / mg 310.8 U / mg Microbiological indicators of the weighed product qualified qualified Temperature of the weighing environment 21℃ 6℃

[0098] Table 2: Comparative experimental data of weighing and dispensing

[0099] Weighing and dispensing time It took 3 hours and 40 minutes. It took 25 minutes. Weigh the portion of the product. 187.4g 187.4g The potency of the product after weighing 297.5 U / mg 333.5 U / mg Microbiological indicators of the weighed product qualified qualified Temperature of the weighing environment 23℃ 5℃

[0100] During the weighing and packaging process of collagenase freeze-dried powder, after 1 hour of weighing and packaging, it is necessary to return the product to an environment of 2-10℃ and store it until the product temperature cools down to 2-10℃ before continuing weighing and packaging. Otherwise, the potency of the collagenase freeze-dried powder may easily decrease. This may be the main reason why the manual weighing and packaging method used in this embodiment takes a long time and results in a decrease in product potency. However, when using the weighing and packaging equipment of this utility model to weigh and package collagenase freeze-dried products, the weighing and packaging time is short, and the product potency remains almost unchanged.

[0101] It should be understood that the specific embodiments described above are merely illustrative or explanatory of the principles of this utility model and do not constitute a limitation thereof. Therefore, any modifications, equivalent substitutions, improvements, etc., made without departing from the spirit and scope of this utility model should be included within its protection scope. Furthermore, the appended claims are intended to cover all variations and modifications falling within the scope and boundaries of the appended claims, or equivalent forms of such scope and boundaries.

Claims

1. A weighing and dispensing device for aseptic cold chain products, characterized in that, It includes the equipment enclosure (1) and the circuit control system (2); The equipment housing (1) includes a weighing module (10), a purification module (20) and a temperature control module (30), which are respectively connected to the circuit control system (2) via data cables; The weighing module (10) includes a weighing platform (11), a weighing sensor (12), a display screen (13), a discharge valve (14), a breathable material cover (15), a material inlet / outlet (16), and an isolation glove (17); the weighing platform (11) is located on top of the weighing sensor (12); the weighing sensor (12) is located at the bottom of the equipment housing (1); the display screen (13) is connected to the weighing sensor (12) via a data cable; the discharge valve (14) is located directly above the weighing platform (11); the material inlet / outlet (16) is located on the side of the equipment housing (1); and the isolation glove (17) is located on the front of the equipment housing (1). The purification module (20) includes an air inlet (21), a filter (22), a fan (23), an anemometer (24), a wall sleeve (25), and an air outlet (26); the air inlet (21) is located at the top of the equipment housing (1); the filter (22) is located below the air inlet (21); the fan (23) is located below the filter (22); the anemometer (24) is located below the filter (22); the wall sleeve (25) is located on the side of the equipment housing (1) and is lower than the horizontal position of the filter (22); the air outlet (26) is located at the bottom of the four sides of the equipment housing (1); The temperature control module (30) includes a cooler (31) and a temperature sensor (32); the cooler (31) is located between the air inlet (21) and the filter (22); the temperature sensor (32) is located below the cooler (31).

2. The weighing and dispensing equipment according to claim 1, characterized in that, The weighing module (10) also includes a material conveying device (18), which includes a material pipe (181), a hopper (182), and a vibration valve (183). One end of the material pipe (181) is fixed to the side of the equipment housing (1), and the other end is fixed to the top of the hopper (14). The end connected to the side of the equipment housing (1) is higher than the end connected to the top of the hopper (14). The material pipe (181) is hollow. The hopper (182) is fixed above the material pipe (181) and communicates with the inside of the material pipe (181). The vibration valve (183) is fixed to the outer wall of the material pipe (181). The vibration valve (183) is connected to the circuit control system (2) via a data cable. The circuit control system (2) is used to control the opening and closing of the vibration valve (183).

3. The weighing and dispensing equipment according to claim 1 or 2, characterized in that, The weighing sensor (12), the feeding valve (14), the material inlet / outlet (16), the fan (23), the cooler (31), and the temperature sensor (32) are connected to the circuit control system (2) via data lines. The data from the weighing sensor (12) and the temperature sensor (32) are fed back to the circuit control system (2). The circuit control system (2) is used to control the opening and closing of the feeding valve (14), the material inlet / outlet (16), the fan (23), and the cooler (31).

4. The weighing and dispensing equipment according to claim 1 or 2, characterized in that, The discharge valve (14) is an electromagnetic discharge valve or a star discharge valve.

5. The weighing and dispensing equipment according to claim 1 or 2, characterized in that, The breathable material cover (15) is provided with multiple breathable holes.

6. The weighing and dispensing equipment according to claim 1 or 2, characterized in that, The filter (22) is a high-efficiency filter.

7. The weighing and dispensing equipment according to claim 1 or 2, characterized in that, The through-wall sleeve (25) is connected to the disinfection equipment outside the equipment box (1).

8. The weighing and dispensing equipment according to claim 1 or 2, characterized in that, The air outlet (26) adopts a hollow plate structure.

9. The weighing and dispensing equipment according to claim 1 or 2, characterized in that, The refrigerator (31) adopts a refrigeration coil structure.

10. The weighing and dispensing equipment according to claim 2, characterized in that, The valve chamber and valve port of the discharge valve (14) are made of anti-static material; the discharge hopper (182) is made of anti-static material; and the equipment housing (1) is made of stainless steel.

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