A cell culture plate separation culture device

Abstract

The utility model relates to cell culture equipment technical field and disclose a cell culture plate separation culture device, including incubator and the equipment box of being located at the upper portion of incubator, be equipped with several culture plate bodies that present vertical arrangement in incubator, the fixed mounting of culture plate body upper portion has the locating frame, culture plate body upper portion is equipped with several mobile rods in the locating frame, mobile rod can carry out position adjustment in the locating frame, mobile rod side is equipped with several elastic clamping rings, and elastic clamping ring has elasticity, and elastic clamping ring can carry out position adjustment in mobile rod side, and two elastic clamping rings carry out the clamping of petri dish. In the utility model, through several elastic clamping rings with elasticity can carry out the clamping fixation of different size cell culture dish, and mobile rod can adjust the position in the locating frame and carry out the fixation, and elastic clamping ring can adjust the fixation in mobile rod side, improve the application scope of this cell separation culture equipment.

Description

Technical Field

[0001] This utility model relates to the field of cell culture equipment technology, specifically a cell culture plate separation and culture device. Background Technology

[0002] Cell culture is a technique used in the laboratory to allow plant and animal cells to grow, differentiate, proliferate, and express specific functions in an artificial environment using specific culture media and conditions. Cell culture is used for experiments to isolate and culture cells.

[0003] A search revealed a patent, CN220284063U, which discloses a cell culture plate separation and culture device. The device includes a culture cabinet with casters rotatably mounted on its bottom. Ultraviolet germicidal lamps are installed on the inner walls of both sides of the cabinet. A culture plate mechanism is slidably mounted inside the cabinet, and separation culture dishes are placed on the culture plate mechanism. A magnetic suction moving mechanism is magnetically attached to one side of the culture plate mechanism. This novel culture plate mechanism can be pulled out via the casters, facilitating observation and removal of separation culture dishes, making it more convenient and intuitive. Multiple sets of separation culture dishes are placed on the placement plate, allowing for simultaneous performance of various cell culture operations. It also facilitates the removal, observation, and replacement of individual culture dishes. The magnetic suction moving mechanism adheres to the separation culture dish when it needs to be removed, creating a seal and preventing spillage of nutrient solution, thus avoiding contamination of the culture environment.

[0004] The aforementioned patents have significant beneficial effects, but in practical application, they still have the following shortcomings: The aforementioned comparative documents describe a method where the culture dish is placed in a slot on a culture plate to secure it, and then used in conjunction with a culture cabinet for cell culture. However, in reality, culture dishes come in various sizes, requiring different sizes depending on the number of cells cultured and environmental factors. The aforementioned comparative documents use a slot to secure the culture dish, but since the slot size is fixed, if a different size of culture dish is needed for cell culture, the entire culture plate must be replaced, thus reducing the applicability of the device. Therefore, there is an urgent need in the art to improve cell culture plate separation and culture devices to overcome the shortcomings of the prior art. Utility Model Content

[0005] To address the shortcomings of existing technologies, this invention provides a cell culture plate separation and culture device, thereby expanding the applicability of the cell separation and culture equipment.

[0006] To achieve the above objectives, this utility model provides the following technical solution: a cell culture plate separation and culture device, including an incubator and an equipment box located on top of the incubator. The incubator contains several vertically arranged culture plates. A positioning frame is fixedly installed on the upper part of each culture plate. Several movable rods located within the positioning frame are provided on the upper part of each culture plate. The movable rods can be adjusted in position within the positioning frame. Several elastic locking rings are provided on the sides of the movable rods. The elastic locking rings are elastic and can be adjusted in position on the sides of the movable rods. Two elastic locking rings clamp the culture dishes.

[0007] Preferably, both ends of the moving rod are provided with first sliding blocks, the opposite sides of the positioning frame are provided with first sliding grooves adapted to the first sliding blocks, and one side of the first sliding block is provided with a first locking bolt extending to the outside and used to limit and fix the first sliding block.

[0008] Preferably, a second sliding block is provided on one side of the elastic snap ring, and a second sliding groove adapted to the second sliding block is provided on both sides of the moving rod. A second locking bolt adapted to the second sliding groove and extending to the top of the moving rod is threadedly connected to the upper part of the second sliding groove.

[0009] Preferably, a plug block is fixedly installed on one side of the elastic snap ring, and a plug groove adapted to the plug block is opened on the side of the second sliding block. A third locking bolt with one end threaded to the bottom of the plug groove passes through the upper part of the plug block.

[0010] Preferably, several mounting brackets are fixedly installed on the inner side wall of the incubator by fasteners, and the culture plate is inserted between the several mounting brackets.

[0011] Preferably, the culture plate has a plurality of through holes that penetrate the culture plate.

[0012] Preferably, the first sliding groove passes through the opposite side of the positioning frame, and one end of the first locking bolt passes through the first sliding block and is threadedly connected to the end of the moving rod.

[0013] To address the shortcomings of existing technologies, this invention provides a cell culture plate isolation and culture device, overcoming the deficiencies of the prior art. The beneficial effects of this invention are as follows: In this invention, several elastic locking rings can clamp and fix cell culture dishes of different sizes, and the moving rod can be adjusted and fixed in position within the positioning frame. The elastic locking rings can be adjusted and fixed on the side of the moving rod, thereby improving the applicability of the cell separation and culture equipment.

[0014] In this invention, by setting the insertion block on the side of the elastic snap ring to insert into the insertion groove on the side of the second sliding block, it is convenient to install or replace the elastic snap ring later. Moreover, when replacing the elastic snap ring, it is not necessary to replace the second sliding block, thus reducing the usage cost when replacing the elastic snap ring.

[0015] In this invention, the first sliding groove passes through the opposite side of the positioning frame, and one end of the first locking bolt passes through the first sliding block and is threadedly connected to the end of the moving rod. This allows for the addition or reduction of the number of moving rods and elastic locking rings according to actual conditions, further improving the applicability of the cell separation device.

[0016] Other features and advantages of this invention will be set forth in the description which follows, and will be apparent in part from the description, or may be learned by practicing the invention. The objects and other advantages of this invention can be realized and obtained by means of the structures pointed out in the description, claims, and drawings. Attached Figure Description

[0017] The accompanying drawings are provided to further understand the present invention and form part of the specification. They are used together with the embodiments of the present invention to explain the present invention and do not constitute a limitation thereof.

[0018] Figure 1 This is a schematic diagram of the overall structure of this utility model; Figure 2 This is a schematic diagram of the structure of a culture plate in this utility model; Figure 3 This is a partial cross-sectional view of the movable rod in this utility model. Figure 4 This is a schematic diagram of the elastic snap ring in this utility model; Figure 5 for Figure 2 Enlarged structural diagram at point A in the middle; Figure 6 for Figure 2 Enlarged structural diagram at point B.

[0019] In the diagram: 1. Incubator; 2. Equipment box; 3. Culture plate; 4. Positioning frame; 5. Moving rod; 6. Elastic snap ring; 7. First sliding block; 8. First sliding groove; 9. First locking bolt; 10. Second sliding block; 11. Second sliding groove; 12. Second locking bolt; 13. Insertion block; 14. Insertion groove; 15. Third locking bolt; 16. Mounting bracket; 17. Through hole. Detailed Implementation

[0020] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0021] Example 1 Please see Figures 1-6 A cell culture plate isolation and culture device includes an incubator 1 and an equipment box 2 located on top of the incubator 1. The incubator 1 contains several vertically arranged culture plates 3. A positioning frame 4 is fixedly installed on the upper part of each culture plate 3. Several movable rods 5 located within the positioning frame 4 are provided on the upper part of each culture plate 3. The movable rods 5 can be adjusted in position within the positioning frame 4. Several elastic locking rings 6 are provided on the side of each movable rod 5. The elastic locking rings 6 are elastic and can be adjusted in position on the side of the movable rod 5. Two elastic locking rings 6 are positioned relative to the culture plate. For clamping, both ends of the moving rod 5 are provided with first sliding blocks 7. The opposite sides of the positioning frame 4 are provided with first sliding grooves 8 that are adapted to the first sliding blocks 7. One side of the first sliding block 7 is provided with a first locking bolt 9 that extends to the outside and is used to limit and fix the first sliding block 7. One side of the elastic snap ring 6 is provided with a second sliding block 10. The adjacent sides of the moving rod 5 are provided with second sliding grooves 11 that are adapted to the second sliding blocks 10. The upper part of the second sliding groove 11 is threaded with a second locking bolt 12 that is adapted to the second sliding groove 11 and extends to the top of the moving rod 5.

[0022] In this specific embodiment, when cells need to be cultured, the cell culture solution is placed in a cell culture dish, and the cell culture dish is inserted between two corresponding elastic locking rings 6 by means of insertion. The elastic locking rings 6 are elastic and can clamp and fix cell culture dishes of different sizes. When the deformation of the elastic locking rings 6 cannot adapt to the cell culture dish, the first sliding block 7 slides in the first sliding groove 8 by moving the moving rod 5, thereby adjusting the spacing between the moving rods 5. After the position of the moving rods 5 is adjusted, the position of the moving rods 5 is limited and fixed by locking the first locking bolt 9. The number of elastic locking rings 6 can be determined according to the size of the cell culture dish. One side of the second sliding block 10 is inserted into the second sliding groove 11, and the spacing between the elastic locking rings 6 is adjusted. After the position of the elastic locking rings 6 is adjusted, the second locking bolt 9 is locked. Tightening bolt 12 adjusts and fixes the position of elastic locking ring 6, which can limit and fix cell culture dishes of different sizes, improving the applicability of the cell separation equipment. After all cell culture dishes are installed, the hinged door on the side of the incubator 1 is closed, and the internal culture environment of the incubator 1 is monitored and adjusted in real time through the equipment box 2. The aforementioned equipment box 2 is a known prior art. The equipment box 2 is equipped with a water tank, a water pump and a heating device. The side of the incubator 1 is equipped with a main controller for controlling the equipment box 2 and the electrical products inside the incubator 1. The incubator 1 is equipped with a sensing device, a heating device and an atomizing head. The sensing device is used to monitor the temperature and humidity inside the incubator 1 in real time, the heating device controls the temperature inside the incubator 1, and the water in the water tank is delivered to the atomizing head by turning on the water pump, and the humidity inside the incubator 1 is controlled by the atomizing head to realize the classification culture of cells.

[0023] Example 2 Please see Figure 4 This embodiment includes the above embodiment, and further includes: a plug block 13 is fixedly installed on one side of the elastic snap ring 6, and a plug groove 14 adapted to the plug block 13 is opened on the side of the second sliding block 10. A third locking bolt 15 is threaded through the upper part of the plug block 13, one end of which is threaded to the bottom of the plug groove 14.

[0024] In this embodiment, when it is necessary to clamp and fix cell culture dishes with large size differences, the elastic locking ring 6 can be replaced. The insertion block 13 on one side of the elastic locking ring 6 is inserted into the insertion groove 14. One end of the third locking bolt 15 passes through the insertion block 13, and the lower end of the third locking bolt 15 is threaded to the bottom of the insertion groove 14. This facilitates the installation or later replacement of the elastic locking ring 6. Moreover, when replacing the elastic locking ring 6, it is not necessary to replace the second sliding block 10, thus reducing the usage cost when replacing the elastic locking ring 6.

[0025] Example 3 Please see Figure 5 and Figure 6 This embodiment includes all the above embodiments, and further includes: a plurality of mounting brackets 16 are fixedly installed on the inner side wall of the incubator 1 by fasteners, the culture plate 3 is inserted between the plurality of mounting brackets 16, the culture plate 3 is provided with a plurality of through holes 17, the through holes 17 penetrate the culture plate 3, the first sliding groove 8 penetrates the opposite side of the positioning frame 4, and one end of the first locking bolt 9 penetrates the first sliding block 7 and is threadedly connected to the end of the moving rod 5.

[0026] In this embodiment, the mounting bracket 16 is fixedly installed on the opposite side wall of the incubator 1 using fasteners in the prior art. The culture plate 3 is inserted between several mounting brackets 16 by plugging. The air in the incubator 1 circulates through the through hole 17 to ensure the balance of the environment inside the incubator 1. The first sliding groove 8 passes through the opposite side of the positioning frame 4. One end of the first locking bolt 9 passes through the first sliding block 7 and is threadedly connected to the end of the moving rod 5. The number of moving rods 5 and the number of elastic locking rings 6 can be added or reduced according to the actual situation, further improving the applicability of the cell separation device.

[0027] All of the electrical products mentioned above can be purchased from the market. They are mature technologies and have been fully disclosed, so they will not be repeated in the instruction manual. All of the electrical products mentioned above are equipped with power cords, and they are electrically connected to the external main controller and 220V phase voltage (or 380V line voltage) through the power cords. The main controller can be a conventional known device such as a computer that plays a control role.

[0028] Finally, it should be noted that in the description of this utility model, the terms "vertical," "upper," "lower," "horizontal," etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this utility model.

[0029] In the description of this utility model, it should also be noted that, unless otherwise explicitly specified and limited, the terms "set," "install," "connect," and "link" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model according to the specific circumstances.

[0030] The above description is merely a preferred embodiment of the present utility model and is not intended to limit the present utility model. Although the present utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. A cell culture plate separation culture device comprising a culture box (1) and a device box (2) arranged at the upper part of the culture box (1), characterized in that, The incubator (1) contains several vertically arranged culture plates (3). A positioning frame (4) is fixedly installed on the upper part of the culture plate (3). Several moving rods (5) located in the positioning frame (4) are provided on the upper part of the culture plate (3). The moving rods (5) can be adjusted in position within the positioning frame (4). Several elastic locking rings (6) are provided on the side of the moving rods (5). The elastic locking rings (6) are elastic and can be adjusted in position on the side of the moving rods (5). Two elastic locking rings (6) clamp the culture dish.

2. The cell culture plate separation and culture device according to claim 1, wherein, The moving rod (5) has a first sliding block (7) at both ends. The positioning frame (4) has a first sliding groove (8) on the opposite side that is adapted to the first sliding block (7). The first sliding block (7) has a first locking bolt (9) extending to the outside and used to limit and fix the first sliding block (7) on one side.

3. The cell culture plate separation and culture device according to claim 1, wherein, A second sliding block (10) is provided on one side of the elastic snap ring (6), and a second sliding groove (11) adapted to the second sliding block (10) is provided on both sides of the moving rod (5). A second locking bolt (12) adapted to the second sliding groove (11) and extending to the top of the moving rod (5) is threadedly connected to the upper part of the second sliding groove (11).

4. The cell culture plate separation and culture device according to claim 1, wherein, A plug block (13) is fixedly installed on one side of the elastic snap ring (6). The side of the second sliding block (10) is provided with a plug groove (14) that is compatible with the plug block (13). A third locking bolt (15) is threaded through the upper part of the plug block (13) and one end is threaded to the bottom of the plug groove (14).

5. The cell culture plate separation and culture device according to claim 1, wherein, The inner wall of the incubator (1) is fixed with several mounting brackets (16) by fasteners, and the culture plate (3) is inserted between several mounting brackets (16).

6. The cell culture plate separation and culture device according to claim 1, wherein, The culture plate (3) has several through holes (17) that penetrate the culture plate (3).

7. The cell culture plate separation and culture device according to claim 2, wherein, The first sliding groove (8) passes through the opposite side of the positioning frame (4), and one end of the first locking bolt (9) passes through the first sliding block (7) and is threadedly connected to the end of the moving rod (5).

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