A centrifuge for bulk drug production

Abstract

This utility model relates to the technical field of raw material pharmaceutical production equipment, specifically a centrifuge for raw material pharmaceutical production. It includes a frame, with rotating shafts rotatably mounted on both sides inside the frame. A housing is fixedly installed between the opposite ends of the two rotating shafts. A positioning shaft is rotatably mounted at the bottom inside the housing, and a filter cartridge is fixedly mounted at the top of the positioning shaft. This centrifuge for raw material pharmaceutical production, through the coordinated use of the frame, rotating shafts, housing, filter cartridge, discharge pipe, first servo motor, second servo motor, first gear, second gear, and positioning shaft, allows the filter cartridge to rotate at high speed, causing liquid to seep into the housing and be discharged through the discharge pipe, while solids are retained inside the filter cartridge. After centrifugation, the housing and filter cartridge can be flipped forward, changing the opening from upward to a forward-sloping downward angle. This facilitates the removal of solid pharmaceutical materials from the filter cartridge through a larger opening, providing a better field of vision to ensure thorough removal and also facilitating cleaning of the inside of the housing.

Description

Technical Field

[0001] This utility model relates to the technical field of raw material drug production equipment, specifically a centrifuge for raw material drug production. Background Technology

[0002] In the pharmaceutical manufacturing field, the production quality and efficiency of active pharmaceutical ingredients (APIs) are crucial to the entire pharmaceutical industry. As the basic components of drug formulations, the purity, particle size, and other indicators of APIs directly affect the efficacy and safety of the final drug. Centrifuges, as one of the key pieces of equipment in the API production process, play an indispensable role. During the preparation of APIs, it is often necessary to separate solid-liquid mixtures to obtain pure API solids.

[0003] In traditional active pharmaceutical ingredient (API) production processes, centrifuges often create blind spots in operation due to the unique structure of their filter cartridges, which are typically located inside the centrifuge. This directly leads to extremely cumbersome and inconvenient processes in subsequent steps, such as removing solid pharmaceutical materials from inside the filter cartridges.

[0004] Therefore, it is necessary to provide a centrifuge for the production of active pharmaceutical ingredients to solve the above-mentioned technical problems. Utility Model Content

[0005] The purpose of this invention is to provide a centrifuge for the production of active pharmaceutical ingredients, so as to solve the problems mentioned in the background art.

[0006] To achieve the above objectives, this utility model provides the following technical solution:

[0007] A centrifuge for producing active pharmaceutical ingredients, comprising:

[0008] The frame has rotating shafts rotatably mounted on both sides inside the frame, and a housing is fixedly mounted between the opposite ends of the two rotating shafts. A positioning shaft is rotatably mounted on the bottom inside the housing, and a filter cartridge is fixedly mounted on the top end of the positioning shaft.

[0009] A first servo motor is fixedly installed at the bottom of the housing, and the drive end of the first servo motor passes through the housing and extends into the interior of the housing to be fixedly connected to the bottom end of the positioning shaft.

[0010] A drive mechanism is provided on one side of the outside of the frame.

[0011] Preferably, a cylinder is fixedly installed at the top inside the frame, a movable frame is fixedly installed at the drive end of the cylinder, an annular cover plate is fixedly installed at the bottom of the movable frame, a connecting shaft is fixedly installed at the center of the bottom of the movable frame, and a movable cover plate is rotatably installed at the bottom end of the connecting shaft, and the movable cover plate slides in contact with the inner wall of the annular cover plate.

[0012] Preferably, a number of positioning posts are fixedly installed on the outer side of the bottom of the movable cover plate, and a limiting groove corresponding to the position and number of the positioning posts is opened on the top of the filter cylinder, and the limiting groove is engaged with the positioning posts.

[0013] Preferably, the drive mechanism includes a second servo motor, which is fixedly mounted on one side of the outer surface of the frame. A first gear is fixedly mounted on the drive end of the second servo motor. One end of one of the rotating shafts passes through the frame and extends to one side outside the frame. A second gear is fixedly mounted on one end of one of the rotating shafts, and the second gear meshes with the first gear.

[0014] Preferably, a protective box is fixedly installed on one side of the outer surface of the frame, and the second servo motor, the first gear and the second gear are all located inside the protective box. A controller is fixedly installed on the front of the protective box.

[0015] Preferably, a discharge pipe is fixedly installed on the front side of the bottom of the outer casing.

[0016] Preferably, limit telescopic rods are fixedly installed on both sides of the top inside the frame, and the telescopic ends of the limit telescopic rods are fixedly connected to the top of the movable frame.

[0017] Preferably, a sealing ring is provided at the sliding connection between the movable cover plate and the inner wall of the annular cover plate, and a sealing gasket is provided at the bottom of both the movable cover plate and the annular cover plate.

[0018] Preferably, reinforcing blocks are fixedly installed on the lower sides of both sides inside the frame.

[0019] Compared with the prior art, the beneficial effects of this utility model are:

[0020] 1. This utility model utilizes a frame, rotating shaft, outer shell, filter cartridge, discharge pipe, first servo motor, second servo motor, first gear, second gear, and positioning shaft in conjunction. The high-speed rotation of the filter cartridge causes liquid to seep into the outer shell and be discharged through the discharge pipe, while solids are retained inside the filter cartridge. After centrifugation, the outer shell and filter cartridge can be flipped forward, changing the opening from upward to a forward-sloping downward angle. This allows workers to easily remove the solid medicinal materials from the filter cartridge through a larger opening, ensuring thorough removal and facilitating cleaning of the interior of the outer shell. This significantly improves the convenience of subsequent medicine removal and cleaning processes.

[0021] 2. This utility model utilizes the combined use of an annular cover plate, a movable cover plate, a cylinder, a limiting telescopic rod, a movable frame, a positioning column, and a limiting groove. The annular cover plate and the movable cover plate seal the outer shell and the top of the filter cylinder, preventing material leakage during centrifugation and improving the stability of equipment operation. When the filter cylinder rotates at high speed, the positioning column engages with the limiting groove, causing the movable cover plate to rotate accordingly. This does not obstruct the rotation of the filter cylinder but also serves as a limit, working in conjunction with the connecting shaft to enhance the rotational stability of the filter cylinder and improve operational reliability. After centrifugation, the cover plate moves upward without affecting subsequent unloading and cleaning operations. Attached Figure Description

[0022] Figure 1 This is a three-dimensional structural diagram of the present invention;

[0023] Figure 2 This is a bottom view of the structure of this utility model;

[0024] Figure 3 This is a cross-sectional structural diagram of the present invention;

[0025] Figure 4 This is a schematic diagram of the filter cartridge in this utility model.

[0026] In the diagram: 1. Frame; 2. Rotating shaft; 3. Outer shell; 4. Filter cartridge; 5. Reinforcing block; 6. Annular cover plate; 7. Movable cover plate; 8. Cylinder; 9. Limiting telescopic rod; 10. Movable frame; 11. Protective box; 12. Controller; 13. Discharge pipe; 14. Positioning column; 15. First servo motor; 16. Connecting shaft; 17. Second servo motor; 18. First gear; 19. Second gear; 20. Positioning shaft; 21. Limiting groove. Detailed Implementation

[0027] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0028] Please see Figures 1-4 One embodiment provided by this utility model:

[0029] A centrifuge for producing active pharmaceutical ingredients, comprising:

[0030] The frame 1 has rotating shafts 2 rotatably mounted on both sides inside the frame 1. A housing 3 is fixedly mounted between the opposite ends of the two rotating shafts 2. A positioning shaft 20 is rotatably mounted on the bottom inside the housing 3. A filter cartridge 4 is fixedly mounted on the top of the positioning shaft 20.

[0031] A first servo motor 15 is fixedly installed at the bottom of the housing 3, and the drive end of the first servo motor 15 passes through the housing 3 and extends into the interior of the housing 3 and is fixedly connected to the bottom end of the positioning shaft 20.

[0032] A drive mechanism is provided on one side of the outside of the frame 1.

[0033] A cylinder 8 is fixedly installed at the top inside the frame 1. A movable frame 10 is fixedly installed at the drive end of the cylinder 8. An annular cover plate 6 is fixedly installed at the bottom of the movable frame 10. A connecting shaft 16 is fixedly installed at the center of the bottom of the movable frame 10. A movable cover plate 7 is rotatably installed at the bottom end of the connecting shaft 16. The movable cover plate 7 slides in contact with the inner wall of the annular cover plate 6, so that the annular cover plate 6 and the movable cover plate 7 can move up and down to achieve the effect of closing and opening the top opening of the equipment.

[0034] In one embodiment, several positioning posts 14 are fixedly installed on the outer side of the bottom of the movable cover plate 7. The top of the filter cylinder 4 is provided with limiting grooves 21 corresponding to the position and number of the positioning posts 14, and the limiting grooves 21 are engaged with the positioning posts 14. The engagement between the positioning posts 14 and the limiting grooves 21 drives the movable cover plate 7 to rotate. This allows the movable cover plate 7 to close the top opening of the filter cylinder 4 without hindering the high-speed rotation of the filter cylinder 4. Moreover, the movable cover plate 7 can limit the rotation of the filter cylinder 4. At the upper part of the filter cylinder 4, the movable cover plate 7 and the connecting shaft 16 cooperate to limit the rotation of the filter cylinder 4, enhancing the stability of the rotation of the filter cylinder 4.

[0035] In one preferred embodiment, the drive mechanism includes a second servo motor 17, which is fixedly mounted on one side of the outer surface of the frame 1. A first gear 18 is fixedly mounted on the drive end of the second servo motor 17. One end of a rotating shaft 2 passes through the frame 1 and extends to one side of the outside of the frame 1. A second gear 19 is fixedly mounted on one end of the rotating shaft 2, and the second gear 19 meshes with the first gear 18, which can accurately and stably transmit the power of the second servo motor 17 to the rotating shaft 2 to drive the equipment to operate.

[0036] In one embodiment, a protective box 11 is fixedly installed on one side of the outer surface of the frame 1, and the second servo motor 17, the first gear 18 and the second gear 19 are all located inside the protective box 11. A controller 12 is fixedly installed on the front of the protective box 11. The protective box 11 on one side of the frame 1 houses the second servo motor 17 and other components, which can protect them from damage by external factors. The entire device is controlled by the controller 12. Since the device matched by the controller 12 is a common device and belongs to the existing common knowledge technology, its electrical connection relationship and specific circuit structure will not be described in detail here.

[0037] In one preferred embodiment, a discharge pipe 13 is fixedly installed on the front side of the bottom of the outer casing 3 to facilitate the discharge of the separated liquid medicinal materials.

[0038] In one embodiment, limiting telescopic rods 9 are fixedly installed on both sides of the top inside the frame 1, and the telescopic ends of the limiting telescopic rods 9 are fixedly connected to the top of the movable frame 10, which can limit the movement direction of the movable frame 10 and ensure the stability and accuracy of its vertical movement.

[0039] In one preferred embodiment, a sealing ring is provided at the sliding connection between the movable cover plate 7 and the inner wall of the annular cover plate 6, and a sealing gasket is provided at the bottom of both the movable cover plate 7 and the bottom of the annular cover plate 6, which can enhance the sealing performance, prevent material leakage, and improve the stability of equipment operation.

[0040] In one embodiment, reinforcing blocks 5 are fixedly installed on the lower sides of both sides inside the frame 1 to enhance the structural strength and stability of the frame 1 and ensure more reliable equipment operation.

[0041] The working principle of this invention is as follows: During the equipment operation phase, the raw material is fed into the filter cylinder 4 through the top opening. Then, the first servo motor 15 is started, its drive end rotating the positioning shaft 20. The rotation of the positioning shaft 20 causes the filter cylinder 4 to rotate at high speed. The high-speed rotation of the filter cylinder 4 performs solid-liquid separation. The liquid seeps into the outer shell 3 through the filter holes on the filter cylinder 4 and is discharged through the discharge pipe 13, while the solid material is retained inside the filter cylinder 4. After the centrifugation of the raw material is completed, the first servo motor 15 is stopped, and then the second servo motor 17 is started. Its drive end drives the first gear 18 to rotate. Through the meshing transmission between the first gear 18 and the second gear 19, the first gear 18 drives the rotating shaft 2 to rotate. Since the outer shell 3 and the rotating shaft 2 are fixedly connected, the rotation of the rotating shaft 2 causes the outer shell 3 to rotate. The filter cylinder 4 moves synchronously with the outer shell 3 via the positioning shaft 20, causing the outer shell 3 and the filter cylinder 4 to flip forward. Initially, the openings of the outer shell 3 and filter cylinder 4 face upwards. As the rotation angle changes, the openings of the outer shell 3 and filter cylinder 4 tilt forward and downwards. At this time, workers can easily remove the solid medicinal materials inside the filter cylinder 4 through the larger opening, with a good field of vision, ensuring thorough removal of the medicine. In addition, this also facilitates cleaning of the inside of the outer shell 3, effectively improving the convenience of the equipment in subsequent medicine removal and cleaning processes.

[0042] When the raw material is added into the filter cylinder 4 through the top opening, the cylinder 8 is activated. Its drive end moves the movable frame 10 vertically, and the annular cover 6 moves synchronously. At the same time, the movable frame 10 moves the movable cover 7 via the connecting shaft 16, causing the movable cover 7 and the annular cover 6 to move downwards. The annular cover 6 closes at the upper end of the sandwich formed by the outer shell 3 and the filter cylinder 4, while the movable cover 7 directly seals the top opening of the filter cylinder 4. The positioning post 14 at the bottom of the movable cover 7 is inserted into the limiting groove 21 at the top of the filter cylinder 4. By sealing the open structure of the outer shell 3 and the top of the filter cylinder 4 through the annular cover 6 and the movable cover 7, material leakage during subsequent centrifugation of the medicinal materials can be effectively prevented, improving the stability of equipment operation. In addition, when the filter cylinder 4 rotates at high speed, the movable cover 7 will rotate through the engagement of the positioning post 14 and the limiting groove 21. This ensures that the movable cover 7 can seal the top opening of the filter cylinder 4 without hindering its high-speed rotation. Furthermore, the movable cover plate 7 can limit the rotation of the filter cartridge 4. At the upper part of the filter cartridge 4, the movable cover plate 7 works in conjunction with the connecting shaft 16 to limit the rotation of the filter cartridge 4, enhancing the stability of the filter cartridge 4's rotation and preventing the filter cartridge 4 from relying solely on the positioning shaft 20 for single-point support during operation, thereby improving the operational reliability of the filter cartridge 4. Additionally, after the centrifugation operation is completed, controlling the upward movement of the annular cover plate 6 and the movable cover plate 7 will not affect the subsequent angle adjustment of the outer shell 3 and the filter cartridge 4 for unloading and cleaning operations.

[0043] The foregoing has shown and described the basic principles, main features, and advantages of this utility model. Those skilled in the art should understand that this utility model is not limited to the above embodiments. The embodiments and descriptions in the specification are merely preferred examples and are not intended to limit the utility model. Various changes and modifications can be made to this utility model without departing from its spirit and scope, and all such changes and modifications fall within the scope of the claimed utility model. The scope of protection of this utility model is defined by the appended claims and their equivalents.

Claims

1. A centrifuge for producing active pharmaceutical ingredients, characterized in that, It includes: A frame (1) has rotating shafts (2) rotatably mounted on both sides inside the frame (1). A housing (3) is fixedly mounted between the opposite ends of the two rotating shafts (2). A positioning shaft (20) is rotatably mounted at the bottom inside the housing (3). A filter cartridge (4) is fixedly mounted at the top of the positioning shaft (20). The bottom of the outer shell (3) is fixedly installed with a first servo motor (15), and the drive end of the first servo motor (15) passes through the outer shell (3) and extends into the interior of the outer shell (3) to be fixedly connected to the bottom end of the positioning shaft (20). A drive mechanism is provided on one side of the outside of the frame (1).

2. The centrifuge for producing active pharmaceutical ingredients according to claim 1, characterized in that: A cylinder (8) is fixedly installed at the top inside the frame (1). A movable frame (10) is fixedly installed at the drive end of the cylinder (8). An annular cover plate (6) is fixedly installed at the bottom of the movable frame (10). A connecting shaft (16) is fixedly installed at the center of the bottom of the movable frame (10). A movable cover plate (7) is rotatably installed at the bottom end of the connecting shaft (16), and the movable cover plate (7) slides in contact with the inner wall of the annular cover plate (6).

3. A centrifuge for producing active pharmaceutical ingredients according to claim 2, characterized in that: Several positioning posts (14) are fixedly installed on the outer side of the bottom of the movable cover plate (7). The top of the filter cylinder (4) is provided with a limiting groove (21) corresponding to the position and number of the positioning posts (14), and the limiting groove (21) is engaged with the positioning posts (14).

4. A centrifuge for producing active pharmaceutical ingredients according to claim 1, characterized in that: The drive mechanism includes a second servo motor (17), which is fixedly mounted on one side of the outer surface of the frame (1). A first gear (18) is fixedly mounted on the drive end of the second servo motor (17). One end of a rotating shaft (2) passes through the frame (1) and extends to one side outside the frame (1). A second gear (19) is fixedly mounted on one end of the rotating shaft (2), and the second gear (19) meshes with the first gear (18).

5. A centrifuge for producing active pharmaceutical ingredients according to claim 4, characterized in that: A protective box (11) is fixedly installed on one side of the outer surface of the frame (1), and the second servo motor (17), the first gear (18) and the second gear (19) are all located inside the protective box (11). A controller (12) is fixedly installed on the front of the protective box (11).

6. A centrifuge for producing active pharmaceutical ingredients according to claim 1, characterized in that: A discharge pipe (13) is fixedly installed on the front side of the bottom of the outer shell (3).

7. A centrifuge for producing active pharmaceutical ingredients according to claim 2, characterized in that: Limiting telescopic rods (9) are fixedly installed on both sides of the top of the frame (1), and the telescopic ends of the limiting telescopic rods (9) are fixedly connected to the top of the movable frame (10).

8. A centrifuge for producing active pharmaceutical ingredients according to claim 2, characterized in that: A sealing ring is provided at the sliding connection between the movable cover plate (7) and the inner wall of the annular cover plate (6), and a sealing gasket is provided at the bottom of both the movable cover plate (7) and the annular cover plate (6).

9. A centrifuge for producing active pharmaceutical ingredients according to claim 1, characterized in that: Reinforcing blocks (5) are fixedly installed on the lower sides of both sides inside the frame (1).

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