Plug-in limiting type biological sample sampling and detecting integrated device

Abstract

The utility model provides a kind of plug-in limit type biological sample sampling detection integrated device, it is related to biological sample sampling technical field, including container main body, sampling rod and plug-in limit piece. Container main body is equipped with liquid containing cavity and test paper support installation cavity, distal end is equipped with drainage passage;Sealing membrane is equipped between liquid containing cavity and drainage passage, and container main body proximal end is equipped with sampling port. Sampling rod is inserted in the inside of liquid containing cavity, distal end is equipped with knife edge, and proximal end is connected container cover. Plug-in limit piece includes the limit open loop with notch in one side, and the limit open loop is sleeved in the part of sampling rod proximal end close to container cover, and container cover is blocked in the proximal end side of limit open loop to make the knife edge of sampling rod overhang in the proximal end side of sealing membrane. The utility model can realize dry and wet separation, effectively improve the convenience and stability of device in carrying, storage and transportation process, it is convenient to realize on-site rapid detection, improve the accuracy and reliability of detection result, and simple structure, convenient operation.

Description

Technical Field

[0001] This utility model relates to the field of biological sample sampling technology, and in particular to an integrated device for insertion and removal limiting of biological sample sampling and detection. Background Technology

[0002] With the rapid development of medical diagnostic technology, point-of-care testing is becoming increasingly widely used in clinical diagnosis and home health monitoring. Traditional biosample testing usually requires sending samples to a professional laboratory for analysis, a process involving multiple steps and stages.

[0003] In existing technologies, biological sample collection typically utilizes box-shaped storage dishes, primarily for temporary sample storage and transportation. After collection, the sample needs to be diluted by a technician before being added to the reaction chamber, and results can only be observed after several minutes of reaction time. This separation of sampling and detection results in a significant time lag between sample collection and analysis, increasing the risk of sample contamination or spoilage. Furthermore, in traditional testing devices, reagents and test strips are stored separately. This design not only increases operational complexity but also makes the device prone to liquid leakage during carrying, storage, and transportation, further affecting the accuracy and reliability of test results. Utility Model Content

[0004] The purpose of this invention is to provide an integrated device for sampling and testing biological samples with plug-in limiting mechanism, so as to alleviate the above-mentioned technical problems existing in the prior art.

[0005] To achieve the above objectives, the embodiments of this utility model adopt the following technical solutions: This utility model provides an integrated device for plug-in limiting biological sample collection and detection, comprising: The container body has radially separated liquid-containing cavities and test strip holder mounting cavities inside. Along the axial direction of the container body, the container body has a proximal end and a distal end. The distal end of the container body has a drainage channel inside. The distal end of the test strip holder mounting cavity communicates with the drainage channel. The container body has a test strip mounting channel that communicates with the test strip holder mounting cavity and can be opened and closed. A sealing membrane is provided between the distal end of the liquid-containing cavity and the drainage channel to separate the liquid-containing cavity and the drainage channel. The proximal end of the container body has a sampling port that communicates with the liquid-containing cavity. A sampling rod is inserted into the liquid-containing cavity, with a blade at its distal end and a container cap that can seal the sampling port at its proximal end. The device includes a pluggable limiting device, comprising a limiting ring with a notch on one side, the limiting ring being fitted onto the proximal end of the sampling rod near the container cap, the container cap being blocked by the proximal end of the limiting ring so that the blade of the sampling rod is suspended above the proximal end of the sealing membrane; the limiting ring can disengage from the sampling rod radially to release the sampling rod, and the blade cuts the sealing membrane when the container cap is pressed distally.

[0006] In an optional embodiment, the container body has an extension portion one and an extension portion two protruding in the proximal direction on its proximal side, and a slot is formed between the extension portion one and the extension portion two along the radial direction of the container body; the sampling port passes through the extension portion one along the axial direction of the container body and passes through the side of the extension portion one facing the slot. The limiting ring can be inserted into or removed from the slot along the radial direction of the container body. When the limiting ring is inserted into the slot, it is fitted onto the outside of the extension and simultaneously blocks the container cap on the proximal side of the limiting ring.

[0007] In an optional embodiment, the second extension is provided with a limiting groove extending along the axial direction of the container body on one side wall facing the first extension, and a limiting protrusion is provided on one side wall of the container lid, the limiting protrusion slidingly engaging with the limiting groove. And / or, the inner surface of the limiting open ring is provided with a locking protrusion; And / or, the pluggable limiting member further includes a handle fixedly or integrally connected to one side of the limiting open ring.

[0008] In an optional embodiment, the container body includes a sleeve, which is inserted into and fixed to the container body through the sampling port, the inner cavity of the sleeve forms the liquid containing cavity, and the sealing film covers the distal end of the sleeve; the sampling rod is inserted into the sleeve through the sampling port.

[0009] In an optional embodiment, a limiting tube is fixed to the inner wall of the container body and extends through the axial direction of the container body, and the sleeve is inserted into the limiting tube. A limiting rib one is provided on the inner sidewall of the proximal end of the limiting tube; a limiting rib two is provided on the outer sidewall of the proximal end of the sleeve; a limiting step is provided on the outer sidewall of the sleeve; the limiting rib two abuts against the proximal end side of the limiting rib one, and the limiting step abuts against the distal end side of the distal end face of the limiting tube.

[0010] In an optional embodiment, the sampling rod is provided with a sealing structure at the part located inside the liquid containing cavity. When the sampling rod is inserted into the liquid containing cavity, the sealing structure cooperates with the inner wall of the liquid containing cavity to seal the gap between the outer wall of the sampling rod and the inner wall of the liquid containing cavity, so as to divide the liquid containing cavity into two parts: a proximal side cavity and a distal side cavity.

[0011] In an optional embodiment, the sealing structure includes at least one sealing ring, which is fitted into an annular sealing groove on the outer circumferential surface of the sampling rod.

[0012] In an optional embodiment, the sampling rod includes a proximal section, a threaded section, and a distal section connected sequentially from the proximal end to the distal end; the cutting edge is fixedly connected to the distal side of the distal section, the threaded section has multiple turns of external thread to form a sample groove, and the sealing structure is provided on the proximal section; Wherein, the diameter of the proximal segment is greater than the diameter of the threaded structure segment, which is greater than the diameter of the distal segment.

[0013] In an optional embodiment, a test strip holder is installed inside the test strip holder mounting cavity. The test strip holder is provided with at least one test strip mounting groove. The two side walls of the test strip mounting groove extending axially are respectively provided with at least one nail-shaped positioning part protruding into the test strip mounting groove for positioning the test strip.

[0014] In an optional embodiment, the container body includes a tubular body and a base; The liquid-containing cavity and the test strip holder mounting cavity are located inside the tubular body; The base includes a bottom wall and a peripheral wall, and the drainage channel is located inside the space enclosed by the bottom wall and the peripheral wall; The distal end of the tubular body is sealed to the peripheral wall of the base.

[0015] The embodiments of this utility model can achieve at least the following beneficial effects: The assembly and usage methods of this embodiment are as follows: The sample liquid is contained inside the liquid-containing cavity, and the test strip holder is installed inside the test strip holder mounting cavity (the installation method includes, but is not limited to, snap-fit). The test strip is fixed on the test strip holder, and the liquid-immersed end of the test strip extends into the drainage channel.

[0016] Initially, the sample liquid is blocked by the sealing membrane and will not enter the test strip holder mounting cavity. The limiting ring is fitted on the proximal end of the sampling rod near the container cap. The container cap is blocked on the proximal side of the limiting ring so that the blade of the sampling rod is suspended on the proximal side of the sealing membrane.

[0017] When taking a sample, position the container body with the proximal end facing up and the distal end facing down, and pull out the sampling rod towards the proximal end to take the sample. After taking the sample, reinsert the sampling rod with the sample into the liquid containing cavity along the sampling port. Keep the container cap blocked on the proximal side of the limiting ring so that the blade of the sampling rod is suspended on the proximal side of the sealing membrane, allowing the sample to be fully lysed. During testing, position the container body with the proximal end facing up and the distal end facing down. Pull out the plug-in limiting device radially along the sampling rod. The limiting ring will disengage from the sampling rod radially to release it. Press the container cap towards the distal end so that the blade at the distal end of the sampling rod cuts the sealing membrane. The lysed sample liquid flows through the opening into the drainage channel and contacts the liquid-immersed end of the test strip. A colored band appears on the test strip reaction plate. Then, observe the test strip reading through the side wall of the liquid-containing cavity.

[0018] In particular, the sidewalls of the liquid-containing cavity are provided with observation windows or are made directly of transparent material.

[0019] The embodiments of this utility model can achieve at least the following beneficial effects: The plug-in limiting biological sample collection and testing integrated device provided in this embodiment of the utility model effectively improves the convenience and stability of the device during carrying, storage and transportation by integrating reagents (or sample solutions) and test strips into the same device, making it easy to achieve rapid on-site testing.

[0020] Furthermore, by setting up a synergistic structure of a sealing membrane and a pluggable limiting component, it is ensured that the blade of the sampling rod will not accidentally contact and puncture the sealing membrane before testing, thereby preventing the reagent in the liquid containing chamber from leaking out when not being tested. This ensures that the test strip holder mounting chamber is always in a dry state before testing, achieving a reliable state of dry and wet separation, which can improve the accuracy and reliability of the test results.

[0021] In actual operation, users only need to pull out the plug-in limiting piece radially along the sampling rod, and then press the container cap near the sampling rod towards the distal end to start the testing process. The operation steps are simple and the response is rapid, which greatly shortens the time interval between sample collection and analysis, reduces the risk of sample being contaminated by the outside world after collection, and thus further improves the accuracy and reliability of the test results.

[0022] In addition, the overall structural design of this embodiment is simple, with few parts and easy assembly process, which not only reduces manufacturing costs but also improves production efficiency.

[0023] Specifically, in the present invention, the term "and / or" indicates that the structure before "and / or" and the structure after "and / or" are set simultaneously or selectively. Attached Figure Description

[0024] To more clearly illustrate the specific embodiments of this utility model or the technical solutions in the prior art, the drawings used in the description of the specific embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of this utility model. For those skilled in the art, other drawings can be obtained from these drawings without creative effort.

[0025] Figure 1 A schematic diagram of the overall structure of the pluggable limiting biological sample collection and detection integrated device provided in this embodiment of the utility model; Figure 2 An exploded view of the overall structure of the pluggable limiting biological sample sampling and detection integrated device provided in this embodiment of the utility model; Figure 3 A schematic diagram of the overall structure of the sampling rod in the pluggable limiting biological sample sampling and detection integrated device provided in this embodiment of the utility model; Figure 4 A schematic diagram of the overall structure of the pluggable limiting component in the pluggable limiting biological sample sampling and detection integrated device provided in this embodiment of the utility model; Figure 5 A schematic diagram of the internal structure of the tubular main body of the container in the pluggable limiting biological sample sampling and testing integrated device provided in this embodiment of the utility model; Figure 6 A schematic diagram of the overall structure of the sleeve in the plug-in limiting biological sample sampling and detection integrated device provided in this embodiment of the utility model; Figure 7 A schematic diagram of the overall structure of the test strip holder in the pluggable limiting biological sample sampling and detection integrated device provided in this embodiment of the utility model; Figure 8 A schematic diagram of the overall structure of the base in the plug-in limiting biological sample sampling and testing integrated device provided in this embodiment of the utility model.

[0026] Icons: 1-Container body; 11-Tubular body; 111-Extension 1; 112-Extension 2; 1121-Limiting groove; 1101-Slot; 12-Base; 121-Positioning rib 2; 122-Limiting rib; 101-Liquid receiving cavity; 102-Test paper holder mounting cavity; 103-Drainage channel; 1031-Drainage guide slope; 104-Sealing membrane; 2-Sampling rod; 201-Threaded structure section ; 21-Knife edge; 22-Container cap; 221-Limiting protrusion; 3-Pull-out limiting component; 31-Limiting opening ring; 311-Card-positioning protrusion; 32-Handle; 4-Sleeve; 41-Limiting rib two; 42-Limiting step; 5-Limiting tube; 51-Limiting rib one; 6-Sealing structure; 61-Sealing ring; 62-Annular sealing groove; 7-Test paper holder; 71-Test paper mounting groove; 72-Nail-shaped positioning part; 8-Test paper strip. Detailed Implementation

[0027] To make the objectives, technical solutions, and advantages of the embodiments of this utility model clearer, the technical solutions of the embodiments of this utility model will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this utility model, not all embodiments. The components of the embodiments of this utility model described and shown in the accompanying drawings can generally be arranged and designed in various different configurations.

[0028] Therefore, the following detailed description of the embodiments of the present invention provided in the accompanying drawings is not intended to limit the scope of the claimed invention, but merely to illustrate selected embodiments of the invention. All other embodiments obtained by those skilled in the art based on the embodiments of the present invention without inventive effort are within the scope of protection of the present invention.

[0029] It should be noted that similar labels and letters in the accompanying drawings indicate similar items. Therefore, once an item is defined in one accompanying drawing, it does not need to be further defined and explained in subsequent accompanying drawings.

[0030] In the description of this utility model, it should be noted that the terms "upper," "lower," "vertical," "horizontal," "inner," and "outer," etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings, or the orientation or positional relationship commonly used when the utility model product is in use. They are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this utility model. In addition, the terms "first," "second," and "third," etc., are only used to distinguish descriptions and should not be construed as indicating or implying relative importance.

[0031] Furthermore, the terms "horizontal" and "vertical" do not imply that the component must be absolutely horizontal or suspended, but rather that it can be slightly tilted. For example, "horizontal" simply means that its direction is more horizontal than "vertical," and does not mean that the structure must be completely horizontal, but can be slightly tilted.

[0032] In the description of this utility model, it should also be noted that, unless otherwise explicitly specified and limited, the terms "set," "install," and "connect" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model based on the specific circumstances.

[0033] The following detailed description, in conjunction with the accompanying drawings, outlines some embodiments of the present invention. Unless otherwise specified, the following embodiments and features can be combined with each other.

[0034] This embodiment provides an integrated device for pluggable limiting biological sample collection and detection, referring to... Figures 1 to 8 The plug-in limiting biological sample sampling and testing integrated device includes a container body 1, a sampling rod 2, and a plug-in limiting component 3.

[0035] The container body 1 contains a radially separated liquid-containing cavity 101 and a test strip holder mounting cavity 102. Along the axial direction of the container body 1, it has a proximal end and a distal end. A drainage channel 103 is located inside the distal end of the container body 1. The distal end of the test strip holder mounting cavity 102 communicates with the drainage channel 103. A test strip mounting channel, which communicates with the test strip holder mounting cavity 102 and can be opened and closed, is located on the container body 1. A sealing membrane 104 separates the liquid-containing cavity 101 from the drainage channel 103. A sampling port, communicating with the liquid-containing cavity 101, is located at the proximal end of the container body 1. A sampling rod 2 is inserted inside the liquid-containing cavity 101. A blade 21 is located at the distal end of the sampling rod 2, and a container cap 22, capable of sealing the sampling port, is fixedly connected to the proximal end of the sampling rod 2. The pluggable limiting member 3 includes a limiting ring 31 with a notch on one side. The limiting ring 31 is fitted onto the proximal end of the sampling rod 2 near the container cap 22. The container cap 22 is blocked on the proximal side of the limiting ring 31 so that the blade 21 of the sampling rod 2 is suspended on the proximal side of the sealing membrane 104. The limiting ring 31 can disengage from the sampling rod 2 radially to release the sampling rod 2. When the container cap 22 is pressed in the distal direction, the blade 21 cuts the sealing membrane 104.

[0036] The assembly and usage methods of this embodiment are as follows: The sample liquid (reagent) is contained inside the liquid containing cavity 101. The test strip holder 7 is installed inside the test strip holder mounting cavity 102 (the installation method includes but is not limited to snap-fit). The test strip 8 is fixed on the test strip holder 7, and the liquid-immersed end of the test strip 8 extends into the drainage channel 103.

[0037] Initially, the container body 1 is positioned with the proximal end facing upwards and the distal end facing downwards. The sample liquid is blocked by the sealing membrane 104 and will not enter the test strip holder mounting cavity 102. The limiting ring 31 is fitted onto the proximal end of the sampling rod 2 near the container cap 22. The container cap 22 is blocked on the proximal side of the limiting ring 31 so that the blade 21 of the sampling rod 2 is suspended on the proximal side of the sealing membrane 104.

[0038] During sampling, the proximal end of the container body 1 is facing upward and the distal end is facing downward. The sampling rod 2 is pulled out towards the proximal end to take the sample. After sampling, the sampling rod 2 with the sample is reinserted into the liquid containing cavity 101 along the sampling port. The container cap 22 is blocked at the proximal end of the limiting ring 31 so that the blade 21 of the sampling rod 2 is suspended at the proximal end of the sealing membrane 104, allowing the sample to be fully lysed. During testing, the plug-in limiting member 3 is pulled out radially along the sampling rod 2, and the limiting ring 31 is disengaged from the sampling rod 2 radially to release the sampling rod 2. The container cap 22 is pressed towards the distal end, so that the blade 21 at the distal end of the sampling rod 2 cuts the sealing film 104. The lysed sample liquid flows through the opening to the drainage channel 103 and contacts the liquid-immersed end of the test strip 8. A colored band appears on the reaction plate of the test strip 8. Then, the reading of the test strip 8 is observed through the side wall of the liquid containing cavity 101.

[0039] In particular, the sidewalls of the liquid-containing cavity 101 are provided with observation windows or are made directly of transparent material.

[0040] The pluggable limiting biological sample collection and testing integrated device provided in this embodiment effectively improves the convenience and stability of the device during carrying, storage and transportation by integrating reagents (or sample solutions) and test strips into the same device, making it easy to achieve rapid on-site testing.

[0041] Furthermore, by setting up a synergistic structure of the sealing membrane 104 and the pluggable limiting member 3, it is ensured that the blade 21 of the sampling rod 2 will not accidentally contact and puncture the sealing membrane 104 before testing, thereby preventing the reagent in the liquid containing cavity 101 from leaking in the non-testing state, ensuring that the test strip holder mounting cavity 102 is always in a dry state before testing, realizing a reliable state of dry and wet separation, which can improve the accuracy and reliability of the test results.

[0042] In actual operation, the user only needs to pull out the plug-in limiting piece 3 radially along the sampling rod 2, and then press the container cap 22 near the sampling rod 2 in the distal direction to start the detection process. The operation steps are simple and the response is fast, which greatly shortens the time interval between sample collection and analysis, reduces the risk of sample being contaminated by the outside world after collection, and further improves the accuracy and reliability of the test results.

[0043] In addition, the overall structural design of this embodiment is simple, with few parts and easy assembly process, which not only reduces manufacturing costs but also improves production efficiency.

[0044] Reference Figures 1 to 4 In an optional embodiment of this example, the proximal side of the container body 1 is provided with an extension portion 111 and an extension portion 112 protruding in the proximal direction. A slot 1101 is formed between the extension portion 111 and the extension portion 112 along the radial direction of the container body 1. The sampling port passes through the extension portion 111 along the axial direction of the container body 1 and through the side of the extension portion 111 facing the slot 1101. The limiting ring 31 can be inserted into or removed from the slot 1101 along the radial direction of the container body 1. When the limiting ring 31 is inserted into the slot 1101, it is fitted outside the extension portion 111, and at the same time, the container cap 22 is blocked on the proximal side of the limiting ring 31.

[0045] In this optional embodiment, by providing an extension 111 and an extension 112 at the near end of the container body 1, and forming a slot 1101 therebetween, the limiting ring 31 is inserted through the slot 1101 and fitted onto the outside of the extension 111, which can effectively block the container cover 22, preventing the container cover 22 from moving to the far end with the sampling rod 2 in an unexpected state, thereby causing the sealing membrane 104 to be punctured by the blade 21. This improves the sealing stability and anti-misoperation performance of the liquid containing cavity 101 of the container body 1. At the same time, this structure realizes the integrated setting of the installation base of the limiting ring 31 and the sampling port, improving the rationality of the structural layout and space utilization of the device.

[0046] Continue to refer to Figures 1 to 4 In an optional embodiment of this example, the second extension 112 has a limiting groove 1121 extending axially along the container body on one side wall facing the first extension 111, and a limiting protrusion 221 is provided on one side wall of the container cap 22. The limiting protrusion 221 slides in conjunction with the limiting groove 1121. In this optional embodiment, the limiting groove 1121 and the limiting protrusion 221 can be used to guide the relative sliding direction of the sampling rod 2, so that when the sampling rod 2 slides towards the distal end, it can pierce the middle region of the sealing membrane 104 as much as possible along the axial direction of the container body, ensuring the success rate and efficiency of membrane rupture, and allowing the lysed sample liquid to flow fully into the drainage channel 103.

[0047] Continue to refer to Figures 1 to 4 In an optional embodiment of this example, a locking protrusion 311 is provided on the inner surface of the limiting ring 31. Specifically, the locking protrusion 311 can be directly provided on the inner surface of the limiting ring 31, or in a groove on the inner surface of the limiting ring 31. However, the side facing inwards from the limiting ring 31 should protrude beyond other areas of the inner surface of the limiting ring 31. This allows the locking protrusion 311 to press against the outer peripheral wall of the extension 111 when the limiting ring 31 is fitted onto the outside of the extension 111, increasing the locking force during limiting and further improving the reliability of the plug-in limiting member 3 in limiting the container cap 22 and the sampling rod 2.

[0048] Continue to refer to Figures 1 to 4 In an optional embodiment of this example, the pluggable limiting member 3 further includes a handle 32 fixedly or integrally connected to one side of the limiting ring 31. The handle 32 may be a ring structure or other shapes to make it easier to insert or pull out the limiting ring 31.

[0049] Reference Figure 2 , Figure 5 and Figure 6 In an optional embodiment of this example, the container body 1 includes a sleeve 4. The sleeve 4 is inserted into and fixed to the container body 1 through the sampling port. The inner cavity of the sleeve 4 forms a liquid-containing cavity 101. A sealing membrane 104 covers the distal end of the sleeve 4. The sampling rod 2 is inserted into the sleeve 4 through the sampling port. In this optional embodiment, by designing the sleeve 4 and setting the sealing membrane 104 at the distal end of the sleeve 4, a stable installation port (i.e., the distal end of the sleeve 4) is provided for the installation of the sealing membrane 104. This improves the sealing performance of the sealing membrane 104, effectively seals the liquid-containing cavity 101, further prevents sample contamination and leakage, and enhances the integrity and safety of sample preservation. The connection method of the sealing membrane 104 can be, but is not limited to, sealing the distal end of the sleeve 4 by heat pressing.

[0050] Optionally, a limiting tube 5 is fixed to the inner wall of the container body 1, extending axially along the container body 1, and the sleeve 4 is inserted into the limiting tube 5; a limiting rib 51 is provided on the inner side wall of the proximal end of the limiting tube 5; a limiting rib 41 is provided on the outer side wall of the proximal end of the sleeve 4, and a limiting step 42 is provided on the outer side wall of the sleeve 4; the limiting rib 41 abuts against the proximal side of the limiting rib 51, and the limiting step 42 abuts against the distal side of the distal end face of the limiting tube 5. During assembly, it can be assembled by relative rotation. In this optional embodiment, the design of the limiting tube 5 provides a clear positioning and fixing point for the sleeve 4 inside the container body 1. Combined with the abutting design of the first limiting rib 51 and the second limiting rib 41, as well as the abutting design of the limiting step 42 and the far end face of the limiting tube 5, the position of the sleeve 4 inside the container body 1 can be fixed and stable, avoiding displacement or falling off during use, thus improving the structural stability of the overall device. Furthermore, this design simplifies the assembly process, reduces assembly time and complexity, and improves the production efficiency of the device.

[0051] Reference Figure 2 and Figure 3 In an optional embodiment of this invention, a sealing structure 6 is provided at the portion of the sampling rod 2 located inside the liquid containing cavity 101. When the sampling rod 2 is inserted into the liquid containing cavity 101, the sealing structure 6 cooperates with the inner wall of the liquid containing cavity 101 to seal the gap between the outer wall of the sampling rod 2 and the inner wall of the liquid containing cavity 101, thereby dividing the liquid containing cavity 101 into a proximal cavity and a distal cavity. In this optional embodiment, by providing the sealing structure 6, the evaporation of the sample liquid during storage can be prevented. At the same time, it effectively prevents the liquid sample from leaking from the gap between the outer wall of the sampling rod 2 and the inner wall of the liquid containing cavity 101, enhancing the sealing performance of the liquid containing cavity 101 and ensuring the safe storage of the liquid sample.

[0052] Optionally, the sealing structure 6 includes at least one sealing ring 61, which are respectively fitted into the annular sealing grooves 62 on the outer circumferential surface of the sampling rod 2. When the sampling rod 2 is inserted into the liquid receiving cavity 101, each sealing ring 61 is squeezed between the outer wall of the sampling rod 2 and the inner wall of the liquid receiving cavity 101 to achieve a sealing effect.

[0053] Reference Figure 3In an optional embodiment of this example, the sampling rod 2 includes a proximal section, a threaded structure section 201, and a distal section connected sequentially from the proximal end to the distal end. A blade 21 is fixedly connected to the distal side of the distal section. The threaded structure section 201 has multiple external threads forming sample grooves, and a sealing structure 6 is located on its proximal section. The diameter of the proximal section is greater than the diameter of the threaded structure section 201, which is greater than the diameter of the distal section. In this optional embodiment, the threaded structure section 201 provides multiple sample grooves, which is more conducive to holding the sample on the sampling rod 2. The diameter of the proximal section is greater than the diameter of the threaded structure section 201, which is greater than the diameter of the distal section. This reduces the gap between the proximal section of the sampling rod 2 and the inner wall of the liquid-containing cavity 101, improving the sealing effect. Furthermore, it allows the threaded structure section 201 to fully contact and break down the sample liquid. The thinnest distal section facilitates penetration of the sealing membrane 104.

[0054] Reference Figure 7 In an optional embodiment of this example, a test strip holder 7 is installed inside the test strip holder mounting cavity 102. The test strip holder 7 is provided with at least one test strip mounting groove 71. The two side walls of the test strip mounting groove 71 extending axially are respectively provided with at least one nail-shaped positioning part 72 protruding into the test strip mounting groove 71. These nail-shaped positioning parts 72 are used to position the test strip 8.

[0055] Reference Figure 2 and Figure 8 In an optional embodiment of this example, the container body 1 includes a tubular body 11 and a base 12; a liquid containing cavity 101 and a test strip holder mounting cavity 102 are disposed inside the tubular body 11; the base 12 includes a bottom wall and a peripheral wall, and a drainage channel 103 is disposed inside the space enclosed by the bottom wall and the peripheral wall; the distal end of the tubular body 11 is sealed to the peripheral wall of the base 12. In this optional embodiment, the base 12 can be positioned by, but is not limited to, a positioning rib 1 (not shown) disposed on the inner peripheral wall of the tubular body 11 and a positioning rib 2 121 disposed on the outer peripheral wall of the base 12. During assembly, it can be assembled by relative rotation. In the assembled state, the positioning rib 1 abuts against the distal end of the positioning rib 2 121 to achieve a tight connection between the two. The base 12 has a limiting rib 122 on its inner bottom wall to form a drainage channel 103. The surface of the drainage channel 103 forms a drainage guide slope 1031. The height of the drainage guide slope 1031 on the side near the liquid receiving cavity 101 is higher than the height on the side near the test strip holder mounting cavity 102. This allows the lysed sample liquid to be quickly guided to the test strip holder mounting cavity 102 after the far end of the sampling rod 2 pierces the sealing membrane 104, so that the lysed sample liquid can fully contact the liquid-immersed end of the test strip 8, further improving the detection efficiency and the accuracy of the detection results.

[0056] Specifically, when the base 12 is provided, the part where the test strip holder mounting cavity 102 and the base 12 are connected can be regarded as a test strip mounting channel provided on the container body 1 that communicates with the test strip holder mounting cavity 102 and can be opened and closed. The test strip holder 7 can be installed inside the test strip holder mounting cavity 102 by removing the base 12. The installation method includes, but is not limited to, setting a snap-fit ​​structure on the inner wall of the test strip holder mounting cavity 102 to snap the test strip holder 7 onto the inner wall of the test strip holder mounting cavity 102.

[0057] Finally, it should be noted that: 1. In this specification, "and / or" means that the structure before "and / or" and the structure after "and / or" are set simultaneously or selectively; 2. The various embodiments in this specification are described in a progressive manner, with each embodiment focusing on the differences from other embodiments. Similar or identical parts between embodiments can be referred to mutually. The above embodiments in this specification are only used to illustrate the technical solutions of this utility model and are not intended to limit it. Although this utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some or all of the technical features. These modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the various embodiments of this utility model.

Claims

1. A plug-in limiting integrated biological sample collection and detection device, characterized in that, include: The container body has radially separated liquid-containing cavities and test strip holder mounting cavities inside. Along the axial direction of the container body, the container body has a proximal end and a distal end. The distal end of the container body has a drainage channel inside. The distal end of the test strip holder mounting cavity communicates with the drainage channel. The container body has a test strip mounting channel that communicates with the test strip holder mounting cavity and can be opened and closed. A sealing membrane is provided between the distal end of the liquid-containing cavity and the drainage channel to separate the liquid-containing cavity and the drainage channel. The proximal end of the container body has a sampling port that communicates with the liquid-containing cavity. A sampling rod is inserted into the liquid-containing cavity, with a blade at its distal end and a container cap that can seal the sampling port at its proximal end. The device includes a pluggable limiting device, comprising a limiting ring with a notch on one side, the limiting ring being fitted onto the proximal end of the sampling rod near the container cap, the container cap being blocked by the proximal end of the limiting ring so that the blade of the sampling rod is suspended above the proximal end of the sealing membrane; the limiting ring can disengage from the sampling rod radially to release the sampling rod, and the blade cuts the sealing membrane when the container cap is pressed distally.

2. The plug-in limiting integrated biological sample sampling and detection device according to claim 1, characterized in that, The container body has an extension portion one and an extension portion two protruding towards the proximal end. A slot is formed between the extension portion one and the extension portion two along the radial direction of the container body. The sampling port passes through the extension portion one along the axial direction of the container body and passes through the side of the extension portion one facing the slot. The limiting ring can be inserted into or removed from the slot along the radial direction of the container body. When the limiting ring is inserted into the slot, it is fitted onto the outside of the extension and simultaneously blocks the container cap on the proximal side of the limiting ring.

3. The plug-in and limit type biological sample sampling and detection integrated device according to claim 2, characterized in that, The second extension has a limiting groove extending along the axial direction of the container body on one side wall facing the first extension, and the container lid has a limiting protrusion on one side wall, which slides in cooperation with the limiting groove. And / or, the inner surface of the limiting open ring is provided with a locking protrusion; And / or, the pluggable limiting member further includes a handle fixedly or integrally connected to one side of the limiting open ring.

4. The plug-in limiting integrated biological sample collection and detection device according to claim 1, characterized in that, The container body includes a sleeve, which is inserted into the container body through the sampling port and fixed to the container body. The inner cavity of the sleeve forms the liquid containing cavity, and the sealing film covers the distal end of the sleeve. The sampling rod is inserted into the sleeve through the sampling port.

5. The plug-in limiting integrated biological sample collection and detection device according to claim 4, characterized in that, A limiting tube is fixed to the inner wall of the container body and extends through the axial direction of the container body; the sleeve is inserted into the limiting tube. A limiting rib one is provided on the inner sidewall of the proximal end of the limiting tube; a limiting rib two is provided on the outer sidewall of the proximal end of the sleeve; a limiting step is provided on the outer sidewall of the sleeve; the limiting rib two abuts against the proximal end side of the limiting rib one, and the limiting step abuts against the distal end side of the distal end face of the limiting tube.

6. The plug-in limiting integrated biological sample collection and detection device according to claim 1, characterized in that, The sampling rod is provided with a sealing structure at the part inside the liquid containing cavity. When the sampling rod is inserted into the liquid containing cavity, the sealing structure cooperates with the inner wall of the liquid containing cavity to seal the gap between the outer wall of the sampling rod and the inner wall of the liquid containing cavity, so as to divide the liquid containing cavity into two parts: a proximal side cavity and a distal side cavity.

7. The plug-in limiting integrated biological sample sampling and detection device according to claim 6, characterized in that, The sealing structure includes at least one sealing ring, which is fitted inside the annular sealing groove on the outer circumferential surface of the sampling rod.

8. The plug-in limiting integrated biological sample collection and detection device according to claim 6 or 7, characterized in that, The sampling rod includes a proximal section, a threaded section, and a distal section connected sequentially from the proximal end to the distal end; the cutting edge is fixedly connected to the distal side of the distal section, the threaded section has multiple external threads forming a sample groove, and the sealing structure is provided in the proximal section; Wherein, the diameter of the proximal segment is greater than the diameter of the threaded structure segment, which is greater than the diameter of the distal segment.

9. The plug-in limiting integrated biological sample collection and detection device according to claim 1, characterized in that, The test strip holder is installed inside the test strip holder mounting cavity. The test strip holder is provided with at least one test strip mounting groove. The two side walls of the test strip mounting groove extending axially are respectively provided with at least one nail-shaped positioning part protruding into the test strip mounting groove for positioning the test strip.

10. The plug-in limiting integrated biological sample sampling and detection device according to claim 1, characterized in that, The container body includes a tubular body and a base; The liquid-containing cavity and the test strip holder mounting cavity are located inside the tubular body; The base includes a bottom wall and a peripheral wall, and the drainage channel is located inside the space enclosed by the bottom wall and the peripheral wall; The distal end of the tubular body is sealed to the peripheral wall of the base.

Images