Sampling member and biological sample testing device

Abstract

The utility model discloses a kind of sampling components and biological sample detection devices, belong to medical instrument technical field, the sampling component includes handheld part and reaction part, handheld part is fixedly connected with reaction part, handheld part is manually taken, sample groove is opened on reaction part, viscous sample is sampled by sample groove, multiple through-holes are opened on sample groove, still disclose a kind of biological sample detection device, including above-mentioned sampling component, still include main body container, pipe body is connected in main body container, the tail end of pipe body is connected with sealing film, pipe body and sealing film form storage cavity, sampling component can be inserted by the first end of pipe body to storage cavity, make sample on sampling component and test solution in storage cavity crackle.This utility model forms capillary channel by multiple through-holes, when contacting dilute sample, liquid is actively sucked into through-hole due to capillary effect, to sample dilute sample by through-hole, and through-hole edge forms surface tension barrier, can lock dilute sample, avoid drop pollution when sampling.

Description

Technical Field

[0001] This utility model belongs to the field of medical device technology, and in particular relates to a sampling component and a biological sample detection device. Background Technology

[0002] Fecal testing, as a common medical diagnostic method, has wide applications in disease diagnosis and health screening. With advancements in medical technology, the number of fecal testing items is increasing, leading to higher demands on sampling tools. Currently, most fecal samplers on the market adopt traditional spoon-shaped or brush-shaped designs, suitable for collecting fecal samples that are relatively solid or viscous. These samplers typically consist of a sampling head and a handle, and their working principle involves obtaining samples through physical contact and scraping.

[0003] In practical clinical applications, traditional samplers struggle to effectively collect sufficient samples when dealing with loose or watery stools. Due to the high fluidity and poor adhesion of loose stools, existing spoon-shaped samplers cannot effectively collect them, while brush-shaped samplers struggle to adhere a sufficient sample volume. This can lead to insufficient sample volume during subsequent testing, potentially resulting in false negatives and affecting the accuracy of clinical diagnosis, especially potentially causing missed detections of patients testing positive for infectious diseases. Utility Model Content

[0004] The purpose of this invention is to provide a sampling component and a biological sample detection device, which has the advantage of sampling rare samples and solves the problems mentioned in the background art.

[0005] To achieve the above objectives, the specific technical solution of this utility model for a sampling component and a biological sample detection device is as follows: A sampling component includes a handheld part and a reaction part, the handheld part and the reaction part are fixedly connected. The handheld part is for manual handling, and the reaction part is provided with a sample groove for sampling viscous samples. The sample groove is provided with multiple sets of through holes, which form a capillary channel. When it comes into contact with a dilute sample, the liquid is actively drawn into the through holes due to capillary action, so as to sample the dilute sample through the through holes.

[0006] Furthermore, the reaction section includes a rod section and a blade section. The first end of the rod section is fixedly connected to the hand-held part, and the last end of the rod section is fixedly connected to the blade section. The sample slot and the through hole are both opened on the rod section.

[0007] Furthermore, a sealing groove is provided on the rod section, and a sealing ring is connected to the sealing groove. The sealing ring keeps the pyrolysis environment of the sample on the sampling component sealed.

[0008] Furthermore, a limiting rib is fixedly connected to the handheld part to restrict the sampling component to the position of the detection device.

[0009] Furthermore, a disc is connected to the rod section, and a buckle is connected to the disc. When the lysed sample liquid flows to the test strip and reacts with the test strip, the buckle engages with the detection device.

[0010] Furthermore, the handheld part is provided with a threaded section. After the sample and test solution are pyrolyzed, the threaded section is screwed to the detection device. The sampling component rotates towards the tail end of the detection device, and the pyrolyzed sample liquid flows to the test strip and reacts with the test strip.

[0011] A biological sample detection device includes the aforementioned sampling component and a main container. A tube is connected inside the main container, and a sealing film is connected to the tail end of the tube. The tube and the sealing film form a storage cavity for holding a test solution. The sampling component can be inserted into the storage cavity from the head end of the tube, causing the sample on the sampling component to lyse with the test solution in the storage cavity. The sampling component is also sealed to the inner wall of the tube by a sealing ring to seal the storage cavity. A test strip is provided inside the main container. After the sample and test solution have lysed, the sampling component moves towards the tail end of the tube until it punctures the sealing film. The lysed sample liquid flows to the test strip and reacts with it.

[0012] Furthermore, a base is provided at the tail end of the main container, which is connected to the main container. A connecting cavity is provided inside the base. When the sampling component cuts through the sealing film, the lysed sample liquid flows through the connecting cavity to the test strip to react with the test strip.

[0013] Furthermore, a strip holder is connected inside the connecting cavity. The strip holder is used to install the test strip, and the end of the strip holder away from the connecting cavity extends into the detection area.

[0014] Furthermore, a flow channel is provided inside the connecting cavity, through which the lysed sample solution flows to the test strip to react with the test strip.

[0015] This invention has the following advantages: multiple sets of through holes form capillary channels. When in contact with a dilute sample, the liquid is actively drawn into the through holes due to capillary action, so as to sample the dilute sample through the through holes. In addition, the surface tension barrier formed at the edge of the through holes can lock the dilute sample and prevent it from dripping and contaminating during sampling. Attached Figure Description

[0016] To more clearly illustrate the specific embodiments of this utility model or the technical solutions in the prior art, the drawings used in the description of the specific embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of this utility model. For those skilled in the art, other drawings can be obtained from these drawings without creative effort.

[0017] Figure 1 This is a schematic diagram of the first embodiment of the sampling component of this utility model; Figure 2 This is a schematic diagram of the structure of the first embodiment of the detection device of this utility model; Figure 3 This is a cross-sectional structural diagram of the first embodiment of the main container of this utility model; Figure 4 This is a schematic diagram of the structure of the strip card and test strip of this utility model; Figure 5 This is a cross-sectional structural diagram of the base of this utility model; Figure 6 This is a schematic diagram of the second embodiment of the sampling component of this utility model; Figure 7 This is a schematic diagram of the structure of the second embodiment of the detection device of this utility model; Figure 8 This is a cross-sectional structural diagram of the second embodiment of the main container of this utility model; Figure 9 This is a schematic diagram of the structure of the second embodiment of the main container of this utility model; Figure 10 This is a structural schematic diagram of the third embodiment of the sampling component of this utility model; Figure 11 This is a schematic diagram of the third embodiment of the detection device of this utility model; Figure 12 This is a cross-sectional structural diagram of the third embodiment of the main container of this utility model.

[0018] Icons: 1-Main container; 11-Reaction zone; 12-Detection zone; 13-Tube body; 131-Inlet section; 132-Conical section; 133-Sealing section; 134-Card slot; 14-Positioning slot; 15-Limiting slot; 16-Screw groove; 2-Sampling component; 21-Reaction section; 211-Sealing slot; 212-Sample slot; 213-Knife edge section; 214-Disc; 215-Snap-on; 216-Through hole; 22-Handheld part; 23-Limiting rib; 24-Threaded section; 3-Cap; 5-Pattern holder; 6-Test strip; 7-Base; 71-Guide groove; 72-Positioning rib; 8-Sealing film. Detailed Implementation

[0019] The technical solution of this utility model will now be clearly and completely described with reference to the accompanying drawings. Obviously, the described embodiments are only some, not all, of the embodiments of this utility model. Based on the embodiments of this utility model, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this utility model.

[0020] The following is a reference to the appendix. Figure 1 To be continued Figure 12This invention describes a sampling component 2 and a biological sample detection device.

[0021] Currently, most samplers on the market are designed for collecting drier, more viscous stool samples. If the stool is too runny, these samplers are almost unable to collect it, which can lead to false negatives during the reaction test and result in missed detection of positive patients.

[0022] Therefore, the sampling component 2 includes a handheld part 22 and a reaction part 21. The handheld part 22 is fixedly connected to the reaction part 21. The handheld part 22 is for manual handling. The reaction part 21 is provided with a sample groove 212. The viscous sample is sampled through the sample groove 212. The sample groove 212 is provided with multiple sets of through holes 216. The multiple sets of through holes 216 form a capillary channel. When it comes into contact with a dilute sample, the liquid is actively drawn into the through holes 216 due to capillary action, so that the dilute sample can be sampled through the through holes 216. The edge of the through holes 216 forms a surface tension barrier, which can lock the dilute sample and prevent it from dripping and contaminating during sampling.

[0023] Specifically, sample groove 212 is a threaded groove to improve sample adhesion.

[0024] Specifically, multiple sets of through holes 216 are arranged in an array along the axis of the reaction section 21.

[0025] Furthermore, the reaction section 21 includes a rod section and a blade section 213. The first end of the rod section is fixedly connected to the hand-held part 22, and the last end of the rod section is fixedly connected to the blade section 213. The sealing film 8 can be punctured through the blade section 213. The sample groove 212 and the through hole 216 are both opened on the rod section.

[0026] A sealing groove 211 is provided on the rod section, and a sealing ring is connected to the sealing groove 211. The sealing ring keeps the pyrolysis environment of the sample on the sampling component 2 sealed.

[0027] A biological sample detection device includes the aforementioned sampling component 2 and a main container 1. A tube body 13 is connected inside the main container 1, and a sealing film 8 is connected to the tail end of the tube body 13. The tube body 13 and the sealing film 8 form a storage cavity for holding the test solution. The sampling component 2 can be inserted into the storage cavity from the head end of the tube body 13, so that the sample on the sampling component 2 is pyrolyzed with the test solution in the storage cavity. The sampling component 2 is attached to the inner wall of the tube body 13 through a sealing ring to seal the storage cavity. A test strip 6 is provided inside the main container 1. After the sample and test solution are pyrolyzed, the sampling component 2 moves towards the tail end of the tube body 13 until the sampling component 2 punctures the sealing film 8. The pyrolyzed sample liquid flows to the test strip 6 and reacts with the test strip 6. Specifically, the sealing film 8 is an aluminum foil film, and the sealing film 8 is sealed by heat pressing.

[0028] By fitting the sealing ring to the inner wall of the tube body 13, the storage cavity is sealed, avoiding displacement and leakage caused by transportation vibration, thus improving the sealing performance of the storage cavity. Furthermore, the storage cavity is automatically sealed when the sampling component 2 is inserted into the storage cavity from the beginning of the tube body 13.

[0029] A tube body 13 is fixedly connected inside the main container 1, which divides the main container 1 into a reaction zone 11 and a detection zone 12. The inside of the tube body 13 is the reaction zone 11, and the outside of the tube body 13 is the detection zone 12.

[0030] Preferably, the main container 1 is provided with a cover 3 at the front end. The cover 3 is connected to the main container 1 by a buckle 215. By providing the cover 3, the opening is not exposed, which may cause the test solution to evaporate. In addition, the buckle 215 requires a specific force to trigger, which reduces the risk of accidental opening during transportation.

[0031] The tube body 13 is provided with an inlet section 131, a conical section 132 and a sealing section 133. The inlet section 131 is fixedly connected to the large-diameter end of the conical section 132, and the sealing section 133 is fixedly connected to the small-diameter end of the conical section 132. When the sampling component 2 is inserted into the storage cavity from the head end of the tube body 13, it is first inserted through the inlet section 131, and then the position of the sampling component 2 is gradually constrained by the conical section 132. When the sampling component 2 is inserted into place, the head end of the sampling component 2 fits against the sealing section 133, so that the storage cavity is sealed, and then the sample and the test solution are lysed.

[0032] The main container 1 has a base 7 at its tail end. The base 7 has a connecting cavity that connects the reaction zone 11 and the detection zone 12. When the sampling component 2 punctures the sealing film 8, the lysed sample liquid flows through the connecting cavity to the test strip 6 to react with the test strip 6.

[0033] Preferably, the base 7 and the main container 1 are snapped together by a buckle 215. In other embodiments of this utility model, the main container 1 and the base 7 can also be connected by a fixed inclined surface cold extrusion connection.

[0034] A strip holder 5 is connected inside the connecting cavity. The strip holder 5 is used to install the test strip 6. The end of the strip holder 5 away from the connecting cavity extends into the detection area 12. Specifically, a positioning rib 72 is fixedly connected inside the connecting cavity. The strip holder 5 is inserted into the positioning rib 72, and then the strip holder 5 is fixedly connected to the positioning rib 72 by screws.

[0035] The testing area 12 is equipped with an observation window to observe the reading of the test strip 6.

[0036] The connecting cavity is provided with a flow guide 71. The lysed sample solution flows through the flow guide 71 to the test strip 6 to react with the test strip 6. Specifically, the flow guide 71 is inclined so that the lysed sample solution is guided through the flow guide 71.

[0037] First embodiment regarding sampling component 2 and sampling method of detection device A limiting rib 23 is fixedly connected to the handheld part 22, which restricts the sampling component 2 to the position of the detection device. A positioning groove 14 is provided on the main container 1. When the limiting rib 23 is inserted into the positioning groove 14, the sampling component 2 is inserted into the storage cavity, causing the sample and test solution to decompose. After the sample and test solution have decomposed, the sampling component 2 is pressed, and the limiting rib 23 is broken by force. The sampling component 2 moves towards the tail end of the tube body 13 to puncture the sealing film 8. Specifically, when the limiting rib 23 is inserted into the positioning groove 14, the limiting rib 23 blocks the puncture action to ensure that the decomposition is completed. The limiting rib 23 needs a force of 2.5N to break, ensuring the consistency of the puncture stroke. It can be operated by the elderly and children.

[0038] The operation steps of the sampling component 2 and the sampling method of the detection device in the first embodiment are as follows: First, separate the cap from the main container 1. Then, use the sampling component 2 to take the sample. Insert the sampling component 2 with the sample into the tube body 13. At this time, the limiting rib 23 is inserted into the positioning groove 14. Meanwhile, the sealing ring is attached to the inner wall of the tube body 13, so that the sample and the test solution are fully lysed. Then, press the sampling component 2 to break the limiting rib 23. The sampling component 2 moves downward and cuts the sealing film 8 through the cutting edge 213. The lysed sample liquid reacts with the test strip 6 through the break and the guide groove 71. A colored band appears on the plate. Then, observe the reading through the observation window.

[0039] The second embodiment regarding the sampling component 2 and the sampling method of the detection device A limiting rib 23 is fixedly connected to the handle 22, which restricts the sampling component 2 to the position of the detection device. A disc 214 is connected to the rod section, and a buckle 215 is connected to the disc 214. When the lysed sample liquid flows to the test strip 6 and reacts with the test strip 6, the buckle 215 engages with the detection device. A slot 134 is opened in the tube body 13. Specifically, the slot 134 is opened on the inlet section 131. The main container 1 is provided with a positioning groove 14 and a limiting groove 15. Specifically, the limiting rib 23 is inserted into the positioning groove 14 and fixed. When the slot 14 is engaged, the limiting rib 23 blocks the piercing action. The sampling component 2 is inserted into the storage cavity, causing the sample and test solution to lyse. After lysis, the sampling component 2 is rotated so that the limiting rib 23 on the sampling component 2 and the limiting slot 15 are on the same straight line, and the limiting rib 23 can slide along the limiting slot 15. Then the sampling component 2 moves towards the tail end of the tube body 13, and the limiting rib 23 slides along the limiting slot 15 until the buckle 215 engages with the slot 134 to pierce the sealing film 8. The lysed sample liquid flows to the test strip 6 and reacts with the test strip 6.

[0040] The operation steps of the second embodiment of the sampling method of sampling component 2 and detection device are as follows: First, the sampling component 2 is used to collect the sample. Then, the sampling component 2 with the sample is inserted into the tube body 13, and at this time, the limiting rib 23 is inserted into the positioning groove 14. At the same time, the sealing ring is attached to the inner wall of the tube body 13, so that the sample and the test solution are fully pyrolyzed. After the sample and the test solution are fully pyrolyzed, the sampling component 2 rotates around itself as the center, so that the sampling component 2 can slide along the limiting groove 15. Then, the sampling component 2 moves along the limiting groove 15 to move towards the tail end of the tube body 13 until the buckle 215 is engaged with the slot 134. The sealing film 8 is cut through the cutting edge 213 of the sampling component 2. The pyrolyzed sample liquid reacts with the test strip 6 through the break and the guide groove 71. A colored band appears on the plate, and then the reading is observed through the observation window.

[0041] The third embodiment regarding sampling component 2 and sampling method of detection device A limiting rib 23 is fixedly connected to the handheld part 22, which restricts the sampling component 2 to the position of the detection device. A threaded section 24 is provided on the handheld part 22. After the sample and test solution are pyrolyzed, the threaded section 24 is screwed onto the detection device. The sampling component 2 rotates towards the tail end of the detection device, and the pyrolyzed sample liquid flows to the test strip 6 and reacts with it. A screw groove 16 is provided inside the tube body 13, and the threaded section 24 can be screwed onto the screw groove 16. A positioning groove 14 is provided on the main container 1. Specifically, the limiting rib 23 is inserted into... When the sample is inserted into the positioning groove 14 and engaged with it, the limiting rib 23 blocks the piercing action. The sampling component 2 is inserted into the storage cavity, causing the sample and test solution to lyse. After lyse, the sampling component 2 is pressed, and the limiting rib 23 breaks under force. The sampling component 2 moves towards the tail end of the tube body 13 until the threaded section 24 on the sampling component 2 contacts the screw groove 16 and can be screwed in. Then the sampling component 2 rotates along the screw groove 16 towards the tail end of the tube body 13 to cut through the sealing film 8. The lysed sample liquid flows to the test strip 6 and reacts with the test strip 6.

[0042] The operation steps of the second embodiment of the sampling method of sampling component 2 and detection device are as follows: First, the sample is taken using the sampling component 2. Then, the sampling component 2 with the sample is inserted into the tube body 13, and at this time, the limiting rib 23 is inserted into the positioning groove 14. At the same time, the sealing ring is attached to the inner wall of the tube body 13, so that the sample and the test solution are fully lysed. After the sample and the test solution are fully lysed, the sampling component 2 is pressed to break the limiting rib 23 of the sampling component 2, so that the sampling component 2 moves towards the tail end of the tube body 13 until the threaded section 24 on the sampling component 2 contacts the screw groove 16 and can be screwed. Then, the sampling component 2 rotates along the screw groove 16 towards the tail end of the tube body 13, and the sealing film 8 is cut through by the cutting edge section 213 of the sampling component 2. The lysed sample liquid reacts with the test strip 6 through the break and the guide groove 71, and a colored band appears on the plate. Then, the reading is observed through the observation window.

[0043] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of this utility model, and are not intended to limit it. Although the utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some or all of the technical features therein. Such modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of this utility model.

Claims

1. A sampling member, characterized in that, It includes a handheld part (22) and a reaction part (21). The handheld part (22) and the reaction part (21) are fixedly connected. The handheld part (22) is for manual handling. The reaction part (21) is provided with a sample slot (212). The viscous sample is sampled through the sample slot (212). The sample slot (212) is provided with multiple sets of through holes (216). The multiple sets of through holes (216) form a capillary channel. When it comes into contact with a thin sample, the liquid is actively drawn into the through hole (216) due to capillary action, so as to sample the thin sample through the through hole (216).

2. The sampling member of claim 1, wherein, The reaction section (21) includes a rod section and a blade section (213). The first end of the rod section is fixedly connected to the hand-held part (22), and the last end of the rod section is fixedly connected to the blade section (213). The sample groove (212) and the through hole (216) are both opened on the rod section.

3. The sampling member of claim 2, wherein, A sealing groove (211) is provided on the rod section, and a sealing ring is connected to the sealing groove (211). The sealing ring keeps the pyrolysis environment of the sample on the sampling component (2) sealed.

4. The sampling member of claim 1, wherein, A limiting rib (23) is fixedly connected to the handheld part (22), and the sampling component (2) is restricted to the position of the detection device by the limiting rib (23).

5. The sampling member of claim 4, wherein, A disc (214) is connected to the rod section, and a buckle (215) is connected to the disc (214). When the lysed sample liquid flows to the test strip (6) and reacts with the test strip (6), the buckle (215) engages with the detection device.

6. The sampling member of claim 4, wherein, The handheld part (22) has a threaded section (24). After the sample and test solution are pyrolyzed, the threaded section (24) is screwed to the detection device. The sampling component (2) rotates towards the tail end of the detection device, and the pyrolyzed sample liquid flows to the test strip (6) and reacts with the test strip (6).

7. A biological sample testing device comprising a sampling member (2) according to any one of the preceding claims 1-6, characterized in that It also includes a main container (1), a tube (13) connected inside the main container (1), a sealing film (8) connected to the tail end of the tube (13), the tube (13) and the sealing film (8) form a storage cavity, the storage cavity is used to hold the test solution, the sampling component (2) can be inserted into the storage cavity from the head end of the tube (13), so that the sample on the sampling component (2) and the test solution in the storage cavity are pyrolyzed, and the sampling component (2) is attached to the inner wall of the tube (13) through the sealing ring to seal the storage cavity. The main container (1) is provided with a test strip (6). After the sample and the test solution are pyrolyzed, the sampling component (2) moves to the tail end of the tube (13) until the sampling component (2) punctures the sealing film (8), and the pyrolyzed sample liquid flows to the test strip (6) and reacts with the test strip (6).

8. The biological sample testing device of claim 7, wherein, A base (7) is provided at the tail end of the main container (1). The base (7) is connected to the main container (1). A connecting cavity is provided inside the base (7). The sealing film (8) is cut through by the sampling component (2). The lysed sample liquid flows through the connecting cavity to the test strip (6) to react with the test strip (6).

9. The biological sample testing device of claim 8, wherein, A strip holder (5) is connected inside the connecting cavity. The strip holder (5) is used to install the test strip (6). The end of the strip holder (5) away from the connecting cavity extends into the detection area (12).

10. The biological sample testing device of claim 7, wherein, The connecting cavity is provided with a guide groove (71), through which the lysed sample solution flows to the test strip (6) to react with the test strip (6).

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