A sanitary grade ph flow cell assembly

CN224744919UActive Publication Date: 2026-09-11LIXIN WEIKE 3D TECH (SUZHOU) CO LTD
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Patent Information

Application Number
CN202521767875.4
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-08-19
Publication Date
2026-09-11
Estimated Expiration
2035-08-19

AI Technical Summary

Technical Problem

目前现有的技术方案中存在以下几个问题:1、为实现多参数监测往往需要配置多个独立流通池,这不仅增加了系统死腔体积,导致样品稀释和损耗,还降低了检测效率;2、传感器在定期校准时需要人工拆卸,增加了传感器二次损坏的风险;3、不符合生物制药行业卫生级标准,不方便清洗(CIP)且无法做在线蒸汽灭菌(SIP),容易产生介质交叉污染、滋生细菌病毒等有害物质

Benefits of technology

1)本卫生级PH流通池集成了测量模式和校准模式这两种模式,两种模式之间通过把手能够进行切换,当处于测试模式时,PH传感器对检测池中的检测液进行实时检测,检测液的流动路径是:检测液输入接口——进液流道——检测池——出液流道——检测液输出接口,此时存储液输入接口和存储液输出接口是被截断的状态;当转动到“校准模式”下,用存储液对流道和检测池进行冲洗,同时对PH传感器进行校准,此时要隔绝检测液,避免影响校准精度,因此检测液输入接口和检测液输出接口是被截断的状态,而存储液的流动路径是:存储液输入接口——进液流道——检测池——出液流道——存储液输出接口;因此本PH流通池不需要反复拆卸即可同时满足测量和校准两种需求,检测精度高,操作更为简便;

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Abstract

This utility model relates to a sanitary pH flow cell assembly, including a sensor sleeve, a rotating handle assembly, a detection core, and a fixed housing. The detection core contains a detection cell, and the sensor sleeve is sealed to the upper port of the detection cell. A pH sensor is inserted from the top port of the sensor sleeve, and the end of the pH sensor contacts the liquid in the detection cell for pH detection. The detection core has an inlet channel and an outlet channel communicating with the detection cell, which are circumferentially offset by 90°. The outer surface of the detection core has an inlet port for the inlet channel and an outlet port for the outlet channel. A rotating handle assembly is connected to the outer side of the upper part of the detection core, and a fixed housing is located on the outer side of the lower part of the detection core. The outer wall of the fixed housing has a through-hole for the detection liquid input, a detection liquid output, a storage liquid input, and a storage liquid output, which are offset by 90° from each other. This invention ensures the accuracy and hygiene of the pH measurement results of the fluid.
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Description

Technical Field

[0001] This utility model belongs to the field of biopharmaceutical equipment technology, specifically relating to a sanitary pH flow cell component. Background Technology

[0002] Currently, in the biopharmaceutical industry, pH flow cells are devices used for online real-time monitoring of the pH values ​​of critical fluids such as bioreactors, buffer solutions, and culture media. Their technological development has evolved from traditional offline detection to online dynamic monitoring. In pharmaceutical water systems, key detection components such as pressure sensors, temperature sensors, pH electrodes, and conductivity electrodes typically need to be integrated into a specially designed flow cell. Current technical solutions have the following problems: 1. To achieve multi-parameter monitoring, multiple independent flow cells are often required, which not only increases the system's dead space volume, leading to sample dilution and loss, but also reduces detection efficiency; 2. Sensors require manual disassembly during periodic calibration, increasing the risk of secondary sensor damage; 3. They do not meet the sanitary standards of the biopharmaceutical industry, are inconvenient to clean in place (CIP), and cannot be steam-in-place (SIP), easily leading to cross-contamination and the growth of harmful substances such as bacteria and viruses. Utility Model Content

[0003] To address the aforementioned problems and technical needs, this utility model provides a sanitary pH flow cell assembly. This assembly can accommodate a pH electrode and ensure proper contact between the liquid to be tested and the electrode, enabling fluid detection and providing a liquid flow environment that meets sanitary standards, thus ensuring the accuracy, repeatability, and hygiene of pH measurement results.

[0004] The technical solution of this utility model is as follows: A sanitary pH flow cell assembly includes a sensor sleeve, a rotating handle assembly, a detection core, and a fixed housing. The detection core contains a detection cell, and the sensor sleeve is sealed to the upper port of the detection cell. A pH sensor is inserted from the top port of the sensor sleeve, and the end of the pH sensor contacts the liquid in the detection cell for pH detection. The detection core also has an inlet channel and an outlet channel communicating with the detection cell, which are circumferentially offset by 90°. The outer surface of the detection core has an inlet port for the inlet channel and an outlet port for the outlet channel. A rotating handle assembly is connected to the outer side of the upper part of the detection core, and a fixed housing is located on the outer side of the lower part of the detection core. The outer wall of the fixed housing has a through-hole for the detection liquid input and a through-hole for the detection liquid. The four interfaces—the liquid detection output interface, the storage liquid input interface, and the storage liquid output interface—are all staggered by 90°. The rotating handle assembly drives the detection core to rotate around its center. During rotation, the liquid detection input interface and the storage liquid input interface can connect with the inlet hole of the liquid inlet channel, and the liquid detection output interface and the storage liquid output interface can connect with the outlet hole of the liquid outlet channel. Furthermore, when the liquid detection input interface is connected to the inlet hole of the liquid inlet channel, the liquid detection output interface is also connected to the outlet hole of the liquid outlet channel, and at this time, both the storage liquid input interface and the storage liquid output interface are in a closed state. Conversely, when the storage liquid input interface is connected to the inlet hole of the liquid inlet channel, the storage liquid output interface is connected to the outlet hole of the liquid outlet channel, and at this time, both the liquid detection input interface and the storage liquid output interface are in a closed state.

[0005] In the above scheme, the detection core can be switched between "measurement mode" and "calibration mode" by rotating the handle assembly. The liquid flows in from the inlet channel, is detected in the detection pool, and then flows out from the outlet channel. Therefore, the purpose of rotating the detection core is to connect and disconnect the detection liquid input / output interface and the storage liquid input / output interface. When rotated to "measurement mode", the flow path of the detection liquid is: detection liquid input interface - inlet channel - detection pool - outlet channel - detection liquid output interface. At this time, the storage liquid input interface and the storage liquid output interface are disconnected. When rotated to "calibration mode", the flow path of the storage liquid is: storage liquid input interface - inlet channel - detection pool - outlet channel - storage liquid output interface. At this time, the detection liquid input interface and the detection liquid output interface are disconnected.

[0006] Furthermore, the fixed housing includes a base and a cover. The base has a cavity for accommodating the detection core. The cover is fixedly connected to the top of the base by screws. The core of the cover has an assembly hole. The left and right sides of the cover are symmetrically provided with a detection liquid input interface and a storage liquid input interface. The lower part of the front and rear sides of the base is symmetrically provided with a detection liquid output interface and a storage liquid output interface.

[0007] Furthermore, the detection core includes a top cover and a bottom support. The bottom surface of the top cover is machined with the upper cavity of the detection pool, and the top surface of the bottom support is machined with the lower cavity of the detection pool. The top cover and the bottom support are sealed together as one unit by an EPDM sealing gasket and a positioning pin. A connecting cylinder is also provided at the center of the top surface of the top cover. The connecting cylinder is integrally formed with the top cover and is connected to the upper cavity of the detection pool.

[0008] Considering the manufacturing difficulty of the detection cell inside the detection core, the detection core is set into two parts, upper and lower, which reduces the manufacturing difficulty. The top cover and bottom support of the cell can be positioned and locked by the positioning pin. When the top cover rotates, the bottom support can also rotate synchronously. An EPDM sealing gasket is set at the joint to seal and lock the two together, which can ensure that the detection cell is in a sealed state. At the same time, the EPDM sealing gasket has high elasticity and resistance to compression deformation, making it very suitable for use in dynamic sealing scenarios. It also has excellent sealing performance even under long-term rotation, which can effectively prevent liquid leakage.

[0009] Furthermore, the connecting tube is positioned inside the cap assembly hole, and a sensor sleeve is located inside the connecting tube. The cap assembly hole, connecting tube, and sensor sleeve are coaxially aligned. The bottom end of the sensor sleeve is inserted into the upper port of the detection pool. An inner O-ring is located on the inner side of the bottom of the sensor sleeve. When the pH sensor is inserted into the detection pool from inside the sensor sleeve, the inner O-ring seals the contact surface between the pH sensor and the sensor sleeve. An outer O-ring is located on the outer side of the bottom of the sensor sleeve, sealing the contact surface between the sensor sleeve and the connecting tube. The presence of O-rings on both the inner and outer sides of the sensor sleeve ensures that liquid in the detection pool does not seep upwards between the connecting tube and the sensor sleeve, or between the sensor sleeve and the pH sensor during detection, thus improving the sealing performance of the detection pool.

[0010] Furthermore, the cap is pressed on top of the pool top cover, and an upper PTFE sealing gasket is provided between the cap and the pool top cover. The upper PTFE sealing gasket is fixedly connected to the pool top cover, and a round hole is opened at the position of the upper PTFE sealing gasket opposite to the inlet hole of the liquid inlet channel.

[0011] Furthermore, the bottom surface of the pool support is provided with a circular protrusion at the center, and the center of the base is provided with a corresponding circular groove. The pool support and the base are interlocked. A lower PTFE sealing gasket is fixedly connected to the annular end face of the bottom of the pool support around the circular protrusion. A circular hole is also provided at the position of the lower PTFE sealing gasket opposite to the outlet hole of the liquid flow channel.

[0012] Both the upper and lower PTFE gaskets can achieve a sealed connection at the inlet and outlet of the liquid flow channel, allowing the test liquid or cleaning liquid to flow smoothly into the test tank without leakage into the joint. Furthermore, the PTFE gasket material can withstand almost all acids, alkalis, organic solvents, and oxides, and remains stable even after long-term contact with corrosive media. The material is stable and highly applicable.

[0013] Furthermore, the connecting tube is embedded on the outside of the sensor sleeve, and a rotation gap is provided between the outside of the connecting tube and the inner wall of the mounting hole. The rotating handle assembly is connected to the outside of the joint between the sensor sleeve and the connecting tube. The rotating handle assembly drives the detection core to rotate clockwise or counterclockwise through the connecting tube.

[0014] Furthermore, the rotary handle assembly includes a handle and a limiting plate. The middle part of the handle is locked around the outside of the joint between the sensor sleeve and the connecting long cylinder. The middle part of the handle is circular, and the bottom surface of the middle part of the handle is fixedly connected to the limiting plate by screws. The limiting plate is annular, and the bottom surface of the limiting plate has a semi-circular limiting groove. The top surface of the cover has an upwardly protruding cylindrical positioning pin. The cylindrical positioning pin is inserted into the limiting groove. The handle drives the limiting plate, sensor sleeve, and connecting long cylinder to rotate simultaneously. The cylindrical positioning pin limits the rotation angle of the handle to 180° clockwise or 180° counterclockwise. Since the limiting groove that cooperates with the cylindrical positioning pin is semi-circular, that is, the rotation range is 180 degrees in either the forward or reverse direction, this can achieve precise control of the rotation angle, so that the liquid outlets are perfectly aligned each time the rotation is completed.

[0015] Furthermore, the top surface of the cover is marked with indicator arrows for measurement mode and calibration mode, and the handle is rotated according to these arrows. The marked arrows allow for more intuitive switching between the two modes, making operation easier and reducing the likelihood of errors.

[0016] Furthermore, the upper port of the sensor sleeve is provided with an internal thread. After the pH sensor is inserted into the sensor sleeve from the top, it is connected to the sensor sleeve through the internal thread. The threaded connection between the pH sensor and the sensor sleeve allows the end of the pH sensor to be suspended in the detection cell for sampling and detection, resulting in higher stability of the pH sensor and precise control of the insertion depth.

[0017] The beneficial effects of this utility model are: 1) This sanitary pH flow cell integrates both measurement and calibration modes, which can be switched using a handle. In test mode, the pH sensor monitors the test solution in the test cell in real time. The flow path of the test solution is: test solution input interface – inlet channel – test cell – outlet channel – test solution output interface. The storage solution input and output interfaces are disconnected during this mode. When switched to calibration mode, the flow channel and test cell are flushed with the storage solution, and the pH sensor is calibrated simultaneously. During calibration mode, the test solution must be isolated to avoid affecting calibration accuracy. Therefore, the test solution input and output interfaces are disconnected, while the flow path of the storage solution is: storage solution input interface – inlet channel – test cell – outlet channel – storage solution output interface. Therefore, this pH flow cell can simultaneously meet both measurement and calibration needs without repeated disassembly, offering high detection accuracy and simplified operation. 2) The pH detection core is equipped with multiple sealing structures. The upper and lower PTFE sealing gaskets ensure the sealing of the inlet / outlet ports and different interfaces when they are connected, preventing liquid leakage from the joints. The EPDM sealing gasket between the top cover and the bottom support seals the joint between the two, ensuring that no liquid leaks out during the rotation of the detection cell. The EPDM sealing gasket has high elasticity and resistance to compression deformation, making it very suitable for use in dynamic sealing scenarios. The O-rings on the inner and outer sides of the sensor sleeve prevent liquid from leaking out from the top of the detection cell. Therefore, this detection cell has a high sealing effect, is reliable and durable, and avoids the risk of contamination. 3) This pH flow cell assembly enables a single detection cell to be adapted to a single sensor, which can improve detection efficiency and reduce unnecessary waste of the sample to be tested. Attached Figure Description

[0018] Figure 1 This is an isometric sectional view of the assembly of a sanitary pH flow cell assembly according to this utility model; Figure 2 This is a diagram showing the flow path of the detection fluid in measurement mode. Figure 3 This is a diagram showing the state of the storage fluid flow path in test mode; Figure 4 This is a schematic diagram showing the connection between the internal pool top cover and the pool bottom support of this utility model; Figure 5 This is a diagram showing the state of the storage fluid flow path in calibration mode. Figure 6 This is a diagram showing the flow path of the detection fluid in calibration mode. Figure 7 A diagram showing the fit between the rotary handle assembly and the cylindrical locating pin; The components in the diagram are labeled as follows: sensor sleeve 1, internal thread 11, inner O-ring 12, outer O-ring 13, rotating handle assembly 2, handle 21, limiting pressure plate 22, limiting groove 23, detection core 3, connecting long cylinder 31, detection pool 32, liquid inlet channel 33, liquid outlet channel 34, pool top cover 35, upper PTFE sealing gasket 351, pool bottom support 36, lower PTFE sealing gasket 361, round protrusion 362, EPDM sealing gasket 37, positioning pin 38, fixed housing 4, cover 41, detection liquid input interface 411, storage liquid input interface 412, assembly hole 413, cylindrical positioning pin 414, indicator arrow 415, base 42, detection liquid output interface 421, storage liquid output interface 422, round groove 423, screw 43, pH sensor 5. Detailed Implementation

[0019] The present invention will be further described below with reference to the accompanying drawings and embodiments.

[0020] like Figure 1-7 The diagram shows a sanitary pH flow cell assembly of this invention, comprising a sensor sleeve 1, a rotating handle assembly 2, a detection core 3, and a fixed housing 4. The detection core 3 houses a detection cell 32. The sensor sleeve 1 is sealed to the upper port of the detection cell 32. A pH sensor 5 is inserted through the top port of the sensor sleeve 1, with its end contacting the liquid in the detection cell for pH detection. The detection core also has an inlet channel 33 and an outlet channel 34 communicating with the detection cell 32. The inlet channel 33 and the outlet channel 34 are circumferentially offset by 90°. The outer surface of the detection core 3 has an inlet port and an outlet port. The rotating handle assembly 2 is connected to the upper outer side of the detection core 3, and the fixed housing 4 is located on the lower outer side of the detection core 3. The outer wall of the fixed housing 4 has a through-hole for the detection liquid input 411 and a through-hole for the detection liquid output 421. The storage liquid inlet 412 and storage liquid outlet 422 are all staggered by 90°. The rotating handle assembly 2 drives the detection core 3 to rotate around the center. During the rotation, the detection liquid inlet 411 and storage liquid inlet 412 can connect with the inlet hole of the liquid inlet channel, and the detection liquid outlet 421 and storage liquid outlet 422 can connect with the outlet hole of the liquid outlet channel. When the detection liquid inlet 411 is connected to the inlet hole of the liquid inlet channel, the detection liquid outlet 421 is also connected to the outlet hole of the liquid outlet channel. At this time, the storage liquid inlet 412 and storage liquid outlet 422 are both in a closed state. Conversely, when the storage liquid inlet 412 is connected to the inlet hole of the liquid inlet channel, the storage liquid outlet 422 is connected to the outlet hole of the liquid outlet channel. At this time, the detection liquid inlet 411 and detection liquid outlet 421 are in a closed state.

[0021] The fixed housing 4 includes a base 42 and a cover 41. The base 42 has a cavity for accommodating the detection core 3. The cover 41 is fixedly connected to the top of the base 42 by screws 43. The core of the cover 41 has an assembly hole 413. The left and right sides of the cover 41 are symmetrically provided with a detection liquid input interface 411 and a storage liquid input interface 412. The lower part of the front and rear sides of the base 42 is symmetrically provided with a detection liquid output interface 421 and a storage liquid output interface 422.

[0022] The detection core 3 includes a top cover 35 and a bottom support 36. The bottom surface of the top cover 35 is machined with the upper cavity of the detection pool 32, and the top surface of the bottom support 36 is machined with the lower cavity of the detection pool 32. The top cover 35 and the bottom support 36 are sealed and connected as one unit by an EPDM sealing gasket 37 and a positioning pin 38. A connecting cylinder 31 is also provided at the center of the top surface of the top cover 35. The connecting cylinder 31 is integrally formed with the top cover 35 and is connected to the upper cavity of the detection pool 32.

[0023] The connecting tube 31 is disposed inside the cap assembly hole 413. A sensor sleeve 1 is provided inside the connecting tube 31. The cap assembly hole 413, the connecting tube 31, and the sensor sleeve 1 are coaxially arranged. The bottom end of the sensor sleeve 1 is inserted into the upper port of the detection pool 32. An inner O-ring 12 is provided on the inner side of the bottom of the sensor sleeve 1. When the pH sensor 5 is inserted from inside the sensor sleeve 1 into the detection pool 32, the inner O-ring 12 seals the contact surface between the pH sensor 5 and the sensor sleeve 1. An outer O-ring 13 is provided on the outer side of the bottom of the sensor sleeve 1, sealing the contact surface between the sensor sleeve 1 and the connecting tube 31. The presence of O-rings on both the inner and outer sides of the sensor sleeve 1 ensures that liquid in the detection pool does not seep upwards between the connecting tube and the sensor sleeve, or between the sensor sleeve and the pH sensor during detection, thus improving the sealing performance of the detection pool.

[0024] The cap 41 presses down on top of the pool top cover 35. An upper PTFE sealing gasket 351 is provided between the cap 41 and the pool top cover 35. The upper PTFE sealing gasket 351 is fixedly connected to the pool top cover 35. A circular hole is opened at the position of the upper PTFE sealing gasket 351 opposite to the inlet hole of the liquid inlet channel. A circular protrusion 362 is provided at the center of the bottom surface of the pool bottom support 36. A circular groove 423 is provided at the center of the base 42. The pool bottom support 36 and the base 42 are interlocked. A lower PTFE sealing gasket 361 is fixedly connected to the annular end face of the bottom of the pool bottom support 36 around the circular protrusion 362. A circular hole is also opened at the position of the lower PTFE sealing gasket 361 opposite to the outlet hole of the liquid outlet channel.

[0025] The connecting tube 31 is embedded on the outside of the sensor sleeve 1. A rotation gap is provided between the outside of the connecting tube 31 and the inner wall of the mounting hole. The rotating handle assembly 2 is connected to the outside of the joint between the sensor sleeve 1 and the connecting tube 31. The rotating handle assembly 2 drives the detection core to rotate clockwise or counterclockwise through the connecting tube. The rotating handle assembly 2 includes a handle 21 and a limiting plate 22. The middle part of the handle 21 is locked around the outside of the joint between the sensor sleeve 1 and the connecting long cylinder 31. The middle part of the handle 21 is circular. The bottom surface of the middle part of the handle 21 is fixedly connected to the limiting plate 22 by screws. The limiting plate 22 is an annular plate. The bottom surface of the limiting plate 22 has a semi-circular limiting groove 23. The top surface of the cover 41 has an upwardly protruding cylindrical positioning pin 414. The cylindrical positioning pin 414 is inserted into the limiting groove 23. The handle 21 drives the limiting plate 22, the sensor sleeve 1 and the connecting long cylinder 31 to rotate simultaneously. The cylindrical positioning pin 414 limits the rotation angle of the handle 21 to 180° clockwise or 180° counterclockwise.

[0026] The sensor sleeve 1 has an internal thread 11 on the inner side of its upper port. The pH sensor 5 is inserted into the sensor sleeve 1 from the top and connected to it via the internal thread 11. This threaded connection between the pH sensor 5 and the sensor sleeve 1 allows the end of the pH sensor 5 to be suspended in the detection pool for sampling, resulting in higher stability and precise control of the insertion depth. The top surface of the cover 41 is marked with indicator arrows 415 for measurement and calibration modes. The handle 21 is rotated according to these arrows. The marked arrows allow for more intuitive switching between the two modes, simplifying operation and reducing the risk of errors.

[0027] The operating mode of this utility model: like Figure 2-3 To determine the flow path status of the detection liquid and the storage liquid in measurement mode, handle 21 drives the detection core 3 to rotate, so that the detection liquid input interface 411 connects with the inlet hole of the inlet channel 33, and the detection liquid output interface 421 connects with the outlet hole of the outlet channel 34. At this time, the flow path of the detection liquid is: detection liquid input interface - inlet channel - detection pool - outlet channel - detection liquid output interface. In measurement mode, the storage liquid input interface 412 and the storage liquid output interface 422 are cut off. Figure 3 The diagram shows that both the storage liquid inlet 412 and the storage liquid outlet 422 are connected to the blind hole in the detection core 3. However, regardless of whether the blind hole is provided, both interfaces are in a cut-off state, so the structure of the blind hole will not be described in detail. In measurement mode, the bottom of the pH sensor 5 contacts the detection liquid to perform real-time measurement of the detection liquid.

[0028] like Figure 5-6To determine the flow path status of the detection liquid and storage liquid in calibration mode, handle 21 drives the detection core 3 to rotate 180 degrees, aligning the storage liquid input interface 411 with the inlet hole of the inlet channel 33 and the storage liquid output interface 422 with the outlet hole of the outlet channel 34. The flow path of the storage liquid at this time is: storage liquid input interface – inlet channel – detection tank – outlet channel – storage liquid output interface. In calibration mode, the detection liquid input interface 412 and the detection liquid output interface 421 are disconnected. In measurement mode, the pH sensor can be calibrated, and the detection tank 32, inlet channel 33, and outlet channel 34 can be flushed to maintain hygiene within the channels and tank and prevent cross-contamination.

[0029] The above descriptions are merely several preferred embodiments of this utility model, but the scope of protection of this utility model is not limited thereto. Any variations and substitutions that can be easily conceived by those skilled in the art within the technical scope disclosed in this utility model should be included within the scope of protection of this utility model. Therefore, the scope of protection of this utility model should be determined by the scope of the claims.

Claims

1. A sanitary grade PH flow cell assembly characterized by: The system includes a sensor sleeve, a rotating handle assembly, a detection core, and a fixed housing. The detection core contains a detection pool, and the sensor sleeve is sealed to the upper port of the detection pool. A pH sensor is inserted through the top port of the sensor sleeve, with its tip contacting the liquid in the detection pool for pH detection. The detection core also has an inlet channel and an outlet channel communicating with the detection pool, which are circumferentially offset by 90°. The outer surface of the detection core has an inlet port for the inlet channel and an outlet port for the outlet channel. A rotating handle assembly is connected to the upper outer side of the detection core, and a fixed housing is located on the lower outer side of the detection core. The outer wall of the fixed housing has a through-hole for the detection liquid input, a detection liquid output, and a storage liquid input. The four interfaces, including the inlet and storage liquid outlet, are all staggered by 90°. The rotating handle assembly drives the detection core to rotate around the center. During rotation, the detection liquid inlet and storage liquid inlet can connect with the inlet hole of the liquid inlet channel, and the detection liquid outlet and storage liquid outlet can connect with the outlet hole of the liquid outlet channel. When the detection liquid inlet is connected to the inlet hole of the liquid inlet channel, the detection liquid outlet is also connected to the outlet hole of the liquid outlet channel, and at this time, the storage liquid inlet and storage liquid outlet are both in a closed state. Conversely, when the storage liquid inlet is connected to the inlet hole of the liquid inlet channel, the storage liquid outlet is connected to the outlet hole of the liquid outlet channel, and at this time, the detection liquid inlet and detection liquid outlet are in a closed state.

2. A sanitary grade PH flow cell assembly according to claim 1, characterized by: The fixed housing includes a base and a cover. The base has a cavity for accommodating the detection core. The cover is fixedly connected to the top of the base by screws. The core of the cover has an assembly hole. The left and right sides of the cover are symmetrically provided with a detection liquid input interface and a storage liquid input interface. The lower part of the front and rear sides of the base is symmetrically provided with a detection liquid output interface and a storage liquid output interface.

3. The sanitary-grade pH flow tank assembly according to claim 2, characterized in that: The detection core includes a top cover and a bottom support. The bottom surface of the top cover is machined with the upper cavity of the detection pool, and the top surface of the bottom support is machined with the lower cavity of the detection pool. The top cover and the bottom support are sealed together as one unit by an EPDM sealing gasket and a positioning pin. A connecting cylinder is also provided at the center of the top surface of the top cover. The connecting cylinder is integrally formed with the top cover and is connected to the upper cavity of the detection pool.

4. A sanitary grade PH flow cell assembly according to claim 3, wherein: The connecting tube is located inside the cap assembly hole, and a sensor sleeve is provided inside the connecting tube. The cap assembly hole, the connecting tube, and the sensor sleeve are coaxially arranged. The bottom end of the sensor sleeve is inserted into the upper port of the detection pool. An inner O-ring is provided on the inner side of the bottom of the sensor sleeve. When the pH sensor is inserted into the detection pool from inside the sensor sleeve, the inner O-ring seals the contact surface between the pH sensor and the sensor sleeve. An outer O-ring is provided on the outer side of the bottom of the sensor sleeve, which seals the contact surface between the sensor sleeve and the connecting tube.

5. A sanitary pH flow cell assembly according to claim 4, characterized in that: The cap is placed on top of the pool cover, and an upper PTFE sealing gasket is provided between the cap and the pool cover. The upper PTFE sealing gasket is fixedly connected to the pool cover, and a round hole is opened at the position of the upper PTFE sealing gasket opposite to the inlet hole of the liquid inlet channel.

6. A sanitary pH flow cell assembly according to claim 5, characterized in that: The bottom surface of the pool support has a circular protrusion at the center, and the center of the base has a corresponding circular groove. The pool support and the base are interlocked. A lower PTFE sealing gasket is fixedly connected to the annular end face of the bottom of the pool support around the circular protrusion. A circular hole is also opened at the position of the lower PTFE sealing gasket opposite to the outlet hole of the liquid flow channel.

7. A sanitary grade PH flow cell assembly according to claim 6, wherein: The connecting tube is embedded on the outside of the sensor sleeve, and a rotation gap is provided between the outside of the connecting tube and the inner wall of the mounting hole. The rotating handle assembly is connected to the outside of the joint between the sensor sleeve and the connecting tube. The rotating handle assembly drives the detection core to rotate clockwise or counterclockwise through the connecting tube.

8. A sanitary grade PH flow cell assembly according to claim 7, wherein: The rotating handle assembly includes a handle and a limiting plate. The middle part of the handle is locked around the outside of the joint between the sensor sleeve and the connecting long cylinder. The middle part of the handle is circular. The bottom surface of the middle part of the handle is fixedly connected to the limiting plate by screws. The limiting plate is an annular plate with a semi-circular limiting groove on the bottom surface. The top surface of the cover has an upwardly protruding cylindrical positioning pin. The cylindrical positioning pin is inserted into the limiting groove. The handle drives the limiting plate, sensor sleeve and connecting long cylinder to rotate simultaneously. The cylindrical positioning pin limits the rotation angle of the handle to 180° clockwise or 180° counterclockwise.

9. A sanitary pH flow cell assembly according to claim 8, characterized in that: The top surface of the cover is marked with indicator arrows for measurement mode and calibration mode. The handle is rotated according to the indicator arrows.

10. A sanitary grade PH flow cell assembly according to claim 1, characterized by: The upper port of the sensor sleeve is provided with an internal thread. After the PH sensor is inserted into the sensor sleeve from the upper end, it is connected to the sensor sleeve through the internal thread.