A multi-layer pull-out antibody constant temperature incubation box

CN224744970UActive Publication Date: 2026-09-11CHANGSHA MEDICAL UNIV
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Patent Information

Application Number
CN202522045774.2
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-09-23
Publication Date
2026-09-11
Estimated Expiration
2035-09-23

AI Technical Summary

Technical Problem

[0005]为了克服传统抗体孵育盒因单层结构使样本容量受限,导致空间利用率低,需频繁更换孵育盒,影响实验进度的缺点,本实用新型提供一种多层抽拉式抗体恒温孵育盒

Benefits of technology

[0012]有益效果:1、采用多层抽拉结构,通过滑轨与滑块配合实现连接框的灵活抽拉,可同时放置多个抗体样本,大幅提高了单位空间内的样本容纳量,满足多组样本同步孵育的需求,解决了传统抗体孵育盒因单层结构使样本容量受限,导致空间利用率低,需频繁更换孵育盒,影响实验进度的问题。

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Abstract

This utility model relates to the field of biological experimental equipment technology, and in particular to a multi-layer pull-out antibody incubator. This utility model provides such a multi-layer pull-out antibody incubator, including a shell, a sealed door, a control display screen, casters, slide rails, and sliders. The sealed door is rotatably connected to the front of the shell, and the control display screen is installed in front of the sealed door. Multiple casters are rotatably connected to the bottom of the shell. Multiple symmetrically distributed slide rails are fixedly connected to the left and right sides inside the shell, and sliders are slidably connected to each slide rail. The multi-layer pull-out structure, through the cooperation of the slide rails and sliders, allows for flexible pulling out of the connecting frame, enabling the simultaneous placement of multiple antibody samples. This significantly increases the sample capacity per unit space, meeting the needs of simultaneous incubation of multiple samples. It solves the problem of traditional antibody incubators, where the single-layer structure limits sample capacity, resulting in low space utilization and requiring frequent incubator replacements, thus affecting experimental progress.
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Description

Technical Field

[0001] This utility model relates to the field of biological experimental equipment technology, and in particular to a multi-layer pull-out antibody constant temperature incubation box. Background Technology

[0002] Antibody incubators are specialized equipment used in laboratories for antibody incubation. Their core function is to provide a stable constant temperature environment, reduce structural damage to antibodies caused by temperature changes, help maintain antibody activity and binding capacity, improve the accuracy and repeatability of experimental results, and ensure the smooth progress of the specific binding reaction between antibodies and antigens. They are widely used in immunological experiments such as immunohistochemistry and are an important tool for ensuring the standardization of antibody incubation procedures.

[0003] Traditional antibody incubation cassettes still have significant limitations in practical applications. The commonly used single-layer design is inefficient for high-throughput experiments. Due to limited sample capacity, researchers often need to frequently change incubation cassettes, which not only increases operational complexity but also easily introduces human error. In addition, the fixed layered structure results in low space utilization, making it difficult to meet the needs of large-scale experiments and ultimately affecting the overall efficiency and progress of the experiments.

[0004] Therefore, it is necessary to design a multi-layer pull-out antibody constant temperature incubation box. Utility Model Content

[0005] To overcome the shortcomings of traditional antibody incubation boxes, which have limited sample capacity due to their single-layer structure, resulting in low space utilization and the need for frequent replacement of incubation boxes, thus affecting the experimental progress, this invention provides a multi-layer pull-out antibody constant temperature incubation box.

[0006] Technical Solution: A multi-layer pull-out antibody constant temperature incubation box includes a shell, a sealed door, a control display screen, casters, slide rails, sliders, a connecting frame, fixing blocks, pull rings, heating elements, and a temperature sensor. The sealed door is rotatably connected to the front of the shell, and the control display screen is installed in front of the sealed door. Multiple casters are rotatably connected to the bottom of the shell. Multiple symmetrically distributed slide rails are fixedly connected to the left and right sides inside the shell, and sliders are slidably connected to each slide rail. A connecting frame is fixedly connected between two sliders at the same height on the left and right sides. Fixing blocks are fixedly connected inside each connecting frame, and multiple placement slots are provided on each fixing block. Pull rings are rotatably connected to the front of each connecting frame. Multiple heating elements are installed on the left and right sides inside the shell, and a temperature sensor is installed on the rear side inside the shell. Both the heating elements and the temperature sensor are electrically connected to the control display screen.

[0007] In one embodiment, the system also includes rubber sheets, with multiple rubber sheets fixedly connected inside the placement grooves and distributed along the axial direction.

[0008] In one embodiment, an elastic cushioning pad is also included, with the bottom of the connecting frame being fixedly connected to the elastic cushioning pad.

[0009] In one embodiment, a transparent plate and a rubber ring are also included. The transparent plate is fixedly connected inside the sealed door, and the rubber ring is fixedly connected to the rear side of the sealed door, with the rubber ring in contact with the housing.

[0010] In one embodiment, a sign is also included, with the sign fixedly connected to the front side of the connecting frame.

[0011] In one embodiment, the housing is made of thermal insulation material.

[0012] Beneficial effects: 1. The multi-layer pull-out structure, with the sliding rail and slider working together to achieve flexible pulling of the connecting frame, can hold multiple antibody samples at the same time, which greatly increases the sample capacity per unit space and meets the needs of simultaneous incubation of multiple groups of samples. It solves the problem that the traditional antibody incubation box has limited sample capacity due to its single-layer structure, resulting in low space utilization and the need for frequent replacement of incubation boxes, which affects the experimental progress.

[0013] 2. This utility model incorporates a rubber sheet and an elastic buffer pad. The rubber sheet deforms and tightly wraps the sample when it is placed in the incubation device, effectively preventing the sample from shaking due to slight movement or vibration of the device during incubation. The elastic buffer pad provides cushioning during sample placement, preventing the sample from being subjected to severe impact, thereby ensuring the integrity of the sample and improving the accuracy of the experimental results.

[0014] 3. By setting a transparent plate, this utility model allows operators to observe the incubation of antibody samples inside the casing at any time without opening the sealed door, thus avoiding temperature fluctuations inside the casing caused by frequent door opening. Attached Figure Description

[0015] Figure 1 This is a three-dimensional structural diagram of the present invention.

[0016] Figure 2 This is a three-dimensional structural diagram of the slide rail, slider, and connecting frame components of this utility model.

[0017] Figure 3 This is a three-dimensional structural diagram of the components of this utility model, such as the fixing block, pull ring, and rubber sheet.

[0018] Figure 4 This is a partially sectional view of the housing component of this utility model, with some parts obscured.

[0019] Figure 5 This is a three-dimensional structural diagram of the components of this utility model, including the fixing block, rubber sheet, and elastic buffer pad.

[0020] Figure 6This is a three-dimensional structural diagram of the sealing door, transparent plate, and rubber ring components of this utility model.

[0021] Reference numerals: 1_House, 2_Sealed door, 3_Control display screen, 4_Wheel caster, 5_Slide rail, 6_Slider, 7_Connecting frame, 8_Fixing block, 801_Placement slot, 9_Pull ring, 10_Heating element, 11_Temperature sensor, 12_Rubber sheet, 13_Elastic buffer pad, 14_Transparent plate, 15_Rubber ring, 16_Identification plate. Detailed Implementation

[0022] Example: A multi-layer pull-out antibody incubator, such as... Figure 1-6 As shown, the device includes a housing 1, a sealed door 2, a control display screen 3, casters 4, a slide rail 5, a slider 6, a connecting frame 7, a fixing block 8, a pull ring 9, a heating element 10, a temperature sensor 11, and a rubber sheet 12. The housing 1 is made of heat-insulating material to create a constant temperature environment inside the housing, effectively reducing the impact of external temperature on the interior. The sealed door 2 is rotatably connected to the front of the housing 1, and the control display screen 3 is installed in front of the sealed door 2. Two casters 4 are symmetrically distributed on both the front and rear sides of the bottom of the housing 1, enhancing the flexibility of the equipment. Inside the housing 1, the left and right sides... Three symmetrically distributed slide rails 5 are welded on each side, and sliders 6 are slidably connected to each slide rail 5. A connecting frame 7 is welded between two sliders 6 at the same height on the left and right sides. A fixing block 8 is welded inside the connecting frame 7. Multiple placement slots 801 are opened on each fixing block 8. A pull ring 9 is rotatably connected to the front side of the connecting frame 7. Four heating elements 10 are installed on the left and right sides inside the housing 1. A temperature sensor 11 is installed on the rear side inside the housing 1. The heating elements 10 and the temperature sensor 11 are electrically connected to the control display screen 3. Six rubber sheets 12 distributed along the axial direction are glued inside each placement slot 801.

[0023] It also includes an elastic buffer pad 13, a transparent plate 14, a rubber ring 15, and a sign 16. The bottom of the connecting frame 7 is glued with an elastic buffer pad 13. The inside of the sealing door 2 is welded with a transparent plate 14. The back of the sealing door 2 is glued with a rubber ring 15. The rubber ring 15 contacts the housing 1, which enhances the sealing of the device and reduces the temperature loss inside the housing. The front of the connecting frame 7 is welded with a sign 16 to facilitate operators to quickly identify the sample type.

[0024] When antibody samples need to be incubated, the operator first pushes the device to a suitable working position, then locks the casters 4 to secure the device to the ground. Next, the operator rotates the sealing door 2 to open the housing 1. The operator then holds the pull ring 9 in sequence and pulls it forward, thereby driving the slider 6 on the connecting frame 7 to slide forward along the slide rail 5 and pull out. The antibody samples can then be placed one by one into the placement slot 801 on the fixing block 8. The rubber sheet 12 in the placement slot 801 will be squeezed and deformed when the sample is placed, thus tightly wrapping the sample and preventing it from shaking during incubation. The elastic buffer pad 13 plays a buffering role at the moment the sample is placed, avoiding the sample from being violently impacted by the impact force. The operator can mark the sample information on the identification plate 16 for easy identification of the sample later.

[0025] After all samples have been placed, the operator pushes the connecting frame 7 back to reset, then rotates the sealing door 2 in the opposite direction to close the housing 1, and turns on the temperature sensor 11 through the control display screen 3. After the housing 1 is closed, the rubber ring 15 is in close contact with the housing 1 to enhance the sealing of the housing 1 and reduce temperature loss. The operator can observe the antibody samples inside the housing 1 through the transparent plate 14.

[0026] During incubation, temperature sensor 11 monitors the temperature inside housing 1 in real time and transmits the monitored temperature data to control display screen 3. When the monitored temperature is lower than the set target temperature, control display screen 3 immediately activates heating element 10. Heating element 10 is heated and releases heat evenly into housing 1, causing the temperature inside housing 1 to gradually rise until it reaches the preset temperature range. Then, heating element 10 stops heating, keeping the temperature inside housing 1 at the set constant temperature. This completes the incubation process of antibody samples. If antibody samples need to be removed, temperature sensor 11 is turned off, sealing door 2 is rotated again to open housing 1, and then connecting frame 7 is pulled outwards via pull ring 9 to remove antibody samples one by one. After all antibody samples have been removed, connecting frame 7 is pushed back to reset for subsequent use.

Claims

1. A multi-layer pull-out antibody incubator, characterized in that, The system includes a housing (1), a sealed door (2), a control display screen (3), casters (4), slide rails (5), a slider (6), a connecting frame (7), a fixing block (8), a pull ring (9), a heating element (10), and a temperature sensor (11). The front of the housing (1) is rotatably connected to the sealed door (2), and the front of the sealed door (2) is equipped with the control display screen (3). The bottom of the housing (1) is rotatably connected to multiple casters (4). The left and right sides of the interior of the housing (1) are fixedly connected to multiple symmetrically distributed slide rails (5), and each slide rail (5) has multiple rotatable casters (4) on it. The sliding connection has a slider (6), and a connecting frame (7) is fixedly connected between two sliders (6) at the same height on the left and right. A fixing block (8) is fixedly connected inside the connecting frame (7). Multiple placement slots (801) are opened on the fixing block (8). A pull ring (9) is rotatably connected to the front side of the connecting frame (7). Multiple heating elements (10) are installed on the left and right sides inside the housing (1). A temperature sensor (11) is installed on the rear side inside the housing (1). The heating elements (10) and the temperature sensor (11) are electrically connected to the control display screen (3).

2. A multi-layer pull-out antibody incubator according to claim 1, characterized in that, It also includes rubber sheets (12), and multiple rubber sheets (12) are fixedly connected inside the placement groove (801) and distributed along the axial direction.

3. A multi-layer pull-out antibody incubator according to claim 2, characterized in that, It also includes an elastic buffer pad (13), and the bottom of the connecting frame (7) is fixedly connected with an elastic buffer pad (13).

4. A multi-layer pull-out antibody incubator according to claim 3, characterized in that, It also includes a transparent plate (14) and a rubber ring (15). The transparent plate (14) is fixedly connected inside the sealing door (2), and the rubber ring (15) is fixedly connected to the rear side of the sealing door (2). The rubber ring (15) is in contact with the casing (1).

5. A multi-layered pull-through antibody incubation box according to claim 4, characterized in that, It also includes a sign (16), and the front side of the connecting frame (7) is fixedly connected with a sign (16).

6. A multi-layered pull-through antibody incubation box according to claim 5, characterized in that, The casing (1) is made of heat-insulating material.