Improved granulator for pharmaceutical production

Abstract

The utility model relates to the technical field of granulator, disclose an improved granulator for medicine production, including the granulator shell, the utility model discloses a drive motor in starting granulating assembly, and the drive motor output end drives the rotation of the stirring rod along the inner wall of the granulator shell, with the rotation of stirring rod, its outer wall fixed connection a plurality of material -inlet pressure disc, and the material -inlet pressure disc is transported to the extrusion area below with the thrust produced by rotation to the material put into below, and the material is preliminarily dispersed, avoids the material to accumulate and jam below the material inlet, and the material is transported to below by the material -inlet pressure disc, and contacts a plurality of extrusion rotary disc fixedly connected with the outer wall of stirring rod. Extrusion rotary disc rotates with stirring rod, and the material is continuously extruded to produce the force, and the loose powder material is compacted. Under the push of extrusion force, the material is moved to the granulation hole of the surface of the granulator shell, and finally is extruded into shape through the hole of the granulation hole.

Description

Technical Field

[0001] This utility model relates to the field of granulator technology, and in particular to an improved granulator for pharmaceutical production. Background Technology

[0002] In the pharmaceutical manufacturing industry, solid oral dosage forms (such as tablets, capsules, and granules) are among the most widely used dosage forms in clinical practice. Granulation is the core process in the production of solid oral dosage forms. It processes powdered materials (active pharmaceutical ingredients, excipients, etc.) into granules with specific particle size, flowability, and compressibility, solving problems such as powder being easily scattered, uneven mixing, and poor compressibility. This directly affects the uniformity of drug content, dissolution, stability, and clinical efficacy.

[0003] In the existing technology, the feeding and conveying structure of traditional granulators is mostly a single screw conveyor or no active conveying design. Powdered materials are prone to accumulating and clogging below the feed inlet due to poor flowability, requiring frequent manual cleaning. This not only interrupts the production process, but may also introduce impurities due to manual intervention, affecting the quality of the medicine. Utility Model Content

[0004] To solve the above-mentioned technical problems, this utility model provides an improved granulator for pharmaceutical production.

[0005] This utility model is achieved by the following technical solution: an improved granulator for pharmaceutical production, including a granulator shell, a granulation component is provided inside the granulator shell, and an auxiliary component is provided outside the granulator shell.

[0006] The granulation assembly includes a drive motor, a stirring rod is fixedly connected to the output end of the drive motor, the outer wall of the drive motor is fixedly connected to the inner wall of the granulator housing, the inner wall of the granulator housing is provided with heat dissipation holes, the top of the granulator housing is connected to a feed inlet, a feed pressure plate is fixedly connected to the outer wall of the stirring rod, an extrusion disc is fixedly connected to the outer wall of the stirring rod, and granulation holes are provided on the surface of the granulator housing.

[0007] As a further improvement to the above solution, the outer wall of the stirring rod is rotatably connected to the inner wall of the granulator housing, the top of the stirring rod penetrates through the inner wall of the granulator housing and extends therethrough, and the heat dissipation hole penetrates through the inner wall of the granulator housing and extends therethrough.

[0008] As a further improvement to the above solution, several ventilation holes are provided, several feeding pressure plates are provided, the several feeding pressure plates are evenly arranged around the stirring rod, and several extrusion discs are provided.

[0009] Using the above technical solution, the drive motor in the granulation assembly is started, and the output end of the drive motor drives the stirring rod to rotate along the inner wall of the granulator shell. At the same time, several clearance and heat dissipation holes opened on the inner wall of the granulator shell begin to function, dissipating heat from the running drive motor through air circulation, preventing the motor from affecting operational stability due to overheating. The powdered material required for pharmaceutical production is fed into the equipment through the feed port fixedly connected to the top of the granulator shell.

[0010] As a further improvement to the above solution, the auxiliary component includes a guide plate, which is fixedly connected to the outer wall of the pellet mill housing. The outer wall of the pellet mill housing is provided with a guide groove, and an auxiliary unblocking ring is slidably connected to the outer wall of the guide groove.

[0011] As a further improvement to the above solution, a limiting groove is provided on the inner wall of the auxiliary unblocking ring, and an unblocking rod is slidably connected to the inner wall of the limiting groove. The unblocking rod penetrates the inner wall of the auxiliary unblocking ring and is colored. The outer wall of the unblocking rod contacts and is disposed on the surface of the granulator shell.

[0012] As a further improvement to the above solution, a limiting spring is fixedly connected to the end of the unblocking rod away from the granulator housing, and the end of the limiting spring away from the unblocking rod is fixedly connected to the inner wall of the limiting groove.

[0013] As a further improvement to the above solution, a support and storage ring is fixedly connected to the outer wall of the granulator shell, and the outer wall of the unblocking rod is contacted and disposed on the surface of the support and storage ring.

[0014] Through the above technical solution, the guide plate in the auxiliary component is fixedly connected to the outer wall of the granulator shell to receive the drug granules extruded from the granulation hole and prevent the granules from scattering. An auxiliary unblocking ring is slidably connected in the guide groove opened on the outer wall of the granulator shell. In the initial state, the auxiliary unblocking ring can slide up and down along the outer wall of the guide groove; and the outer wall of the unblocking rod is in contact with the surface of the support and receiving ring.

[0015] Compared with the prior art, the beneficial effects of this utility model are as follows:

[0016] This invention activates the drive motor in the granulation assembly, causing the motor output to rotate the stirring rod along the inner wall of the granulator casing. Simultaneously, several ventilation holes on the inner wall of the granulator casing activate, allowing airflow to cool the operating drive motor and preventing overheating that could affect its operational stability. The powdered material required for pharmaceutical production is fed into the equipment through the feed inlet fixedly connected to the top of the granulator casing. As the stirring rod rotates, several feed pressure plates fixedly connected to its outer wall push the material downwards towards the extrusion zone, simultaneously dispersing the material and preventing accumulation and blockage below the feed inlet. The material conveyed downwards by the feed pressure plates contacts several extrusion discs fixedly connected to the outer wall of the stirring rod. These extrusion discs, rotating with the stirring rod, exert a continuous extrusion force on the material, compacting the loose powder. Driven by the extrusion force, the compacted material moves towards the granulation holes on the surface of the granulator shell, and is finally extruded and shaped into drug granules that meet the preset particle size requirements through the channels of the granulation holes, thus avoiding material accumulation and blockage problems from the source. No manual cleaning is required, reducing the number of production interruptions and significantly improving the continuity and efficiency of the granulation process, making it particularly suitable for the continuous and large-scale needs of pharmaceutical production.

[0017] This invention utilizes a guide plate in an auxiliary component, fixedly connected to the outer wall of the granulator housing, to receive the pharmaceutical granules extruded from the granulation orifice and prevent granule scattering. An auxiliary unblocking ring is slidably connected within a guide groove on the outer wall of the granulator housing. Initially, the auxiliary unblocking ring can slide up and down along the outer wall of the guide groove; and the outer wall of the unblocking rod contacts the surface of the support and receiving ring, ensuring the initial stable position of each component of the auxiliary component and providing bottom support. When the granulation component extrudes material through the granulation orifice, some powder material may clog the granulation orifice due to viscosity or particle size issues. At this point, the unblocking rod, slidably connected within the limiting groove on the inner wall of the auxiliary unblocking ring, comes into play: the limiting spring fixedly connected to the inner wall of the limiting groove provides continuous elastic force, pushing the unblocking rod closer to the surface of the pellet mill shell, so that the outer wall of the unblocking rod is in close contact with the surface of the pellet mill shell. As the auxiliary unblocking ring slides up and down along the guide groove, the unblocking rod moves synchronously along the surface of the pellet mill shell, clearing the material blocking the pelleting holes in real time. Through physical contact, the blocking material is pushed out, ensuring that the pelleting holes are always unobstructed, avoiding pelleting interruption or uneven pellet formation due to blockage. After a single unblocking is completed, the limiting spring can use its elastic force to drive the unblocking rod to reset along the inner wall of the limiting groove, returning the unblocking rod to its initial state of contact with the surface of the pellet mill shell, preparing for the next unblocking; at the same time, the auxiliary unblocking ring can slide along the guide groove to the surface of the support and storage ring, completing the component storage. Attached Figure Description

[0018] Figure 1 This is a schematic diagram of the overall structure of this utility model;

[0019] Figure 2 This is a schematic diagram of the granulation component structure of this utility model;

[0020] Figure 3 This is a schematic cross-sectional view of the granulation component of this utility model;

[0021] Figure 4 This is a schematic diagram of the auxiliary component structure of this utility model;

[0022] Figure 5 This utility model Figure 4 Enlarged structural diagram of section A in the middle;

[0023] Figure 6 This is a schematic cross-sectional view of the auxiliary component of this utility model;

[0024] Figure 7 This utility model Figure 6 Enlarged structural diagram of section B.

[0025] Explanation of key symbols:

[0026] 1. Granulator shell; 2. Granulation assembly; 201. Drive motor; 202. Stirring rod; 203. Clearance and heat dissipation holes; 204. Feed inlet; 205. Feeding pressure plate; 206. Extrusion disc; 207. Granulation hole; 3. Auxiliary components; 301. Guide plate; 302. Guide groove; 303. Auxiliary unblocking ring; 304. Limiting groove; 305. Unblocking rod; 306. Limiting spring; 307. Support and storage ring. Detailed Implementation

[0027] The present invention will be further described below with reference to the accompanying drawings and specific embodiments. It should be noted that, without conflict, the various embodiments or technical features described below can be arbitrarily combined to form new embodiments.

[0028] Example:

[0029] Please combine Figure 1-7 An improved granulator for pharmaceutical production according to this embodiment includes a granulator housing 1, a granulation component 2 disposed inside the granulator housing 1, and an auxiliary component 3 disposed outside the granulator housing 1.

[0030] The pelletizing assembly 2 includes a drive motor 201, a stirring rod 202 fixedly connected to the output end of the drive motor 201, the outer wall of the drive motor 201 fixedly connected to the inner wall of the pelletizer housing 1, the inner wall of the pelletizer housing 1 is provided with a heat dissipation hole 203, the top of the pelletizer housing 1 is connected to a feed inlet 204, the outer wall of the stirring rod 202 is fixedly connected to a feed pressure plate 205, the outer wall of the stirring rod 202 is fixedly connected to an extrusion disc 206, and the surface of the pelletizer housing 1 is provided with pelletizing holes 207.

[0031] The outer wall of the stirring rod 202 is rotatably connected to the inner wall of the pellet mill housing 1. The top of the stirring rod 202 penetrates through the inner wall of the pellet mill housing 1 and extends thereto, avoiding the heat dissipation hole 203 which penetrates through the inner wall of the pellet mill housing 1 and extends thereto.

[0032] Several ventilation holes 203 and several feeding pressure plates 205 are provided, evenly arranged around the stirring rod 202. Several extrusion discs 206 are also provided. By starting the drive motor 201 in the pelletizing assembly 2, the output end of the drive motor 201 drives the stirring rod 202 to rotate along the inner wall of the pelletizer housing 1. At the same time, the ventilation holes 203 on the inner wall of the pelletizer housing 1 begin to function, dissipating heat from the running drive motor 201 through air circulation, preventing the motor from overheating and affecting its operational stability.

[0033] The auxiliary component 3 includes a guide plate 301, which is fixedly connected to the outer wall of the pellet mill housing 1. A guide groove 302 is provided on the outer wall of the pellet mill housing 1, and an auxiliary unblocking ring 303 is slidably connected to the outer wall of the guide groove 302.

[0034] The inner wall of the auxiliary unblocking ring 303 is provided with a limiting groove 304, and an unblocking rod 305 is slidably connected to the inner wall of the limiting groove 304. The unblocking rod 305 passes through the inner wall of the auxiliary unblocking ring 303 and is colored. The outer wall of the unblocking rod 305 is in contact with the surface of the pellet mill outer shell 1.

[0035] A limiting spring 306 is fixedly connected to the end of the unblocking rod 305 away from the outer shell 1 of the granulator. The end of the limiting spring 306 away from the unblocking rod 305 is fixedly connected to the inner wall of the limiting groove 304.

[0036] A support and storage ring 307 is fixedly connected to the outer wall of the pellet mill housing 1. The outer wall of the unblocking rod 305 is in contact with the surface of the support and storage ring 307. When the pelleting component 2 extrudes material through the pelleting hole 207, some powder material may clog the pelleting hole 207 due to stickiness or particle size. At this time, the unblocking rod 305, which is slidably connected in the limiting groove 304 opened in the inner wall of the auxiliary unblocking ring 303, plays a role: the limiting spring 306 fixedly connected in the inner wall of the limiting groove 304 provides continuous elastic force, pushing the unblocking rod 305 closer to the surface of the pellet mill housing 1, so that the outer wall of the unblocking rod 305 is in close contact with the surface of the pellet mill housing 1. As the auxiliary unblocking ring 303 slides up and down along the guide groove 302, the unblocking rod 305 moves synchronously along the surface of the pellet mill housing 1, clearing the material blocked in the pelleting hole 207 in real time, and pushing out the blocked material through physical contact.

[0037] The implementation principle of an improved pharmaceutical granulator in this embodiment is as follows: By starting the drive motor 201 in the granulation assembly 2, the output end of the drive motor 201 drives the stirring rod 202 to rotate along the inner wall of the granulator housing 1. Simultaneously, several clearance and heat dissipation holes 203 on the inner wall of the granulator housing 1 begin to function, dissipating heat from the running drive motor 201 through air circulation, preventing the motor from overheating and affecting operational stability. The powdered material required for pharmaceutical production is fed into the equipment through the feed inlet 204 fixedly connected to the top of the granulator housing 1. As the stirring rod 202 rotates, several feed pressure plates 205 fixedly connected to its outer wall push the fed material downwards towards the extrusion area through the thrust generated by the rotation of the feed pressure plates 205, while simultaneously initially dispersing the material to prevent accumulation and blockage below the feed inlet 204. The material conveyed downwards by the feed pressure plates 205 contacts several extrusion discs 206 fixedly connected to the outer wall of the stirring rod 202. The extrusion disc 206 rotates with the stirring rod 202, generating a continuous extrusion force on the material, compacting the loose powder. Driven by this extrusion force, the compacted material moves towards the granulation holes 207 on the surface of the granulator housing 1, and is ultimately extruded through the channels of the granulation holes 207 to form pharmaceutical granules that meet the preset particle size requirements, thus preventing material accumulation and blockage from the source. No manual cleaning is required, reducing production interruptions and significantly improving the continuity and efficiency of the granulation process, making it particularly suitable for the continuous and large-scale needs of pharmaceutical production. Furthermore, the guide disc 301 in the auxiliary component 3 is fixedly connected to the outer wall of the granulator housing 1 to receive the pharmaceutical granules extruded from the granulation holes 207, preventing granule scattering. An auxiliary unblocking ring 303 is slidably connected in the guide groove 302 opened on the outer wall of the pellet mill shell 1. In the initial state, the auxiliary unblocking ring 303 can slide up and down along the outer wall of the guide groove 302; and the outer wall of the unblocking rod 305 is in contact with the surface of the support and storage ring 307, ensuring that the initial position of each component of the auxiliary component 3 is stable and plays a bottom support role. When the pelleting component 2 extrudes the material through the pelleting hole 207 to form the pellet, some powder material may block the pelleting hole 207 due to stickiness or particle size problems.At this time, the unblocking rod 305, which is slidably connected within the limiting groove 304 on the inner wall of the auxiliary unblocking ring 303, comes into play: the limiting spring 306, which is fixedly connected to the inner wall of the limiting groove 304, provides continuous elastic force, pushing the unblocking rod 305 closer to the surface of the pellet mill housing 1, so that the outer wall of the unblocking rod 305 is in close contact with the surface of the pellet mill housing 1. As the auxiliary unblocking ring 303 slides up and down along the guide groove 302, the unblocking rod 305 moves synchronously along the surface of the pellet mill housing 1, clearing the material blocked in the pelleting hole 207 in real time. Unblocking involves physically contacting and pushing out the blockage material to ensure that the granulation hole 207 remains unobstructed, preventing granulation interruption or uneven particle formation due to blockage. After a single unblocking operation is completed, the limit spring 306 can use its elasticity to drive the unblocking rod 305 to reset along the inner wall of the limit slide groove 304, returning the unblocking rod 305 to its initial state of contact with the surface of the granulator housing 1, preparing for the next unblocking operation. At the same time, the auxiliary unblocking ring 303 can slide along the guide slide groove 302 to the surface of the support and storage ring 307 to complete the component storage.

[0038] The above embodiments are merely preferred embodiments of this utility model and should not be construed as limiting the scope of protection of this utility model. Any non-substantial changes and substitutions made by those skilled in the art based on this utility model shall fall within the scope of protection claimed by this utility model.

Claims

1. An improved granulator for pharmaceutical production, characterized in that, It includes a pellet mill housing (1), a pelletizing component (2) is provided inside the pellet mill housing (1), and an auxiliary component (3) is provided outside the pellet mill housing (1). The granulation assembly (2) includes a drive motor (201), a stirring rod (202) is fixedly connected to the output end of the drive motor (201), the outer wall of the drive motor (201) is fixedly connected to the inner wall of the granulator housing (1), the inner wall of the granulator housing (1) is provided with a heat dissipation hole (203), the top of the granulator housing (1) is connected to a feed inlet (204), the outer wall of the stirring rod (202) is fixedly connected to a feed pressure plate (205), the outer wall of the stirring rod (202) is fixedly connected to an extrusion disc (206), and the surface of the granulator housing (1) is provided with a granulation hole (207).

2. The improved granulator for pharmaceutical production as described in claim 1, characterized in that: The outer wall of the stirring rod (202) is rotatably connected to the inner wall of the pellet mill housing (1). The top of the stirring rod (202) penetrates the inner wall of the pellet mill housing (1) and extends therethrough. The heat dissipation hole (203) penetrates the inner wall of the pellet mill housing (1) and extends therethrough.

3. The improved granulator for pharmaceutical production as described in claim 1, characterized in that: The heat dissipation holes (203) are provided in a number of ways, the feeding pressure plate (205) is provided in a number of ways, the feeding pressure plate (205) is provided in a number of ways, the feeding pressure plate (205) is provided in a number of ways, the stirring rod (202) is provided in a number of ways, and the extrusion swivel plate (206) is provided in a number of ways.

4. An improved granulator for pharmaceutical production as described in claim 1, characterized in that: The auxiliary component (3) includes a guide plate (301), which is fixedly connected to the outer wall of the pellet mill housing (1). The outer wall of the pellet mill housing (1) is provided with a guide groove (302), and an auxiliary unblocking ring (303) is slidably connected to the outer wall of the guide groove (302).

5. An improved granulator for pharmaceutical production as described in claim 4, characterized in that: The inner wall of the auxiliary unblocking ring (303) is provided with a limiting groove (304), and the inner wall of the limiting groove (304) is slidably connected to a unblocking rod (305). The unblocking rod (305) penetrates the inner wall of the auxiliary unblocking ring (303) and is colored. The outer wall of the unblocking rod (305) is in contact with the surface of the pellet mill outer shell (1).

6. An improved granulator for pharmaceutical production as described in claim 5, characterized in that: The end of the unblocking rod (305) away from the granulator housing (1) is fixedly connected to a limiting spring (306), and the end of the limiting spring (306) away from the unblocking rod (305) is fixedly connected to the inner wall of the limiting groove (304).

7. An improved granulator for pharmaceutical production as described in claim 6, characterized in that: The outer wall of the granulator housing (1) is fixedly connected to a support and storage ring (307), and the outer wall of the unblocking rod (305) is in contact with the surface of the support and storage ring (307).

Images