A nanosphere microencapsulation device for polypeptide active ingredients

Abstract

The utility model discloses a kind of nanosphere microcapsule wrapping devices for polypeptide active ingredient, including spray head, connecting pipe, connecting mechanism and external pipe;The utility model connects the connecting pipe of external pipe with the rear end of spray head by connecting mechanism, optimizes the cumbersome inconvenience of traditional threaded bolt installation disassembly, forms modular disassembly structure, can effectively improve the efficiency of spray head installation disassembly, to facilitate the cleaning operation of spray head, connecting mechanism includes moving sleeve, covering sleeve, fixed outer ring, spring two and locking mechanism etc. Component, under mutual cooperation can realize the multi-stage sealing locking effect of connecting pipe and external pipe, effectively improve installation stability and sealing effect, simple and stable structure, with stronger practicality.

Description

Technical Field

[0001] This invention relates to the field of microencapsulation technology, specifically to a nanosphere microencapsulation device for peptide active ingredients. Background Technology

[0002] In the field of nanosphere microcapsule encapsulation technology, advanced technologies such as electrostatic spraying are widely used to achieve efficient encapsulation of sensitive active ingredients such as peptides. This type of method can prepare nanocapsules with uniform particle size and excellent morphology by atomizing the drug solution with an electric charge at the end of the nozzle.

[0003] However, the nozzles in some existing devices are mostly fixed or threaded, making disassembly cumbersome, requiring tools and consuming a lot of time. This may result in low efficiency in equipment cleaning and product changeover, potentially affecting the continuity and reliability of production, making it difficult to meet the requirements of compliant and efficient production, and thus having certain limitations. Utility Model Content

[0004] The purpose of this invention is to provide a nanosphere microcapsule encapsulation device for polypeptide active ingredients, so as to solve the problems mentioned in the background art.

[0005] To achieve the above objectives, the present invention adopts the following technical solution: a nanosphere microcapsule encapsulation device for polypeptide active ingredients, comprising a nozzle, a set of connecting tubes connected to the rear end of the nozzle, an outer tube connected to the rear end of the connecting tubes, and the front end of the outer tube connected to the connecting tubes through a connecting mechanism; The rear end of the connecting pipe is connected to a set of connecting rings. There are no fewer than two sets of movable grooves at equal intervals on the outer side of the connecting rings. Each movable groove is provided with a set of fixed curved arms, and each movable groove is connected to a set of top blocks by a spring near the connecting pipe.

[0006] Preferably, the connecting mechanism includes a movable sleeve, a covering sleeve, a fixed outer ring, a second spring, and a locking mechanism. A set of movable sleeves is provided at the front end of the outer tube, a set of covering sleeves is provided at the rear of the movable sleeves near the outer side, and a set of fixed outer rings is provided at the front end of the outer tube corresponding to the position of the covering sleeves. A set of second springs is provided on the front end face of the fixed outer rings, and the other end of the second springs is connected to the rear of the movable sleeves.

[0007] Preferably, the inner side of the movable sleeve is provided with a corresponding movable groove recovery groove, and the inner end of the recovery groove is connected to a set of limiting beads by a spring.

[0008] Preferably, the locking mechanism includes a slot, a linkage groove, and a linkage rod. The front end face of the outer tube is provided with a slot corresponding to the connecting ring. The inner side of each slot is provided with a linkage groove corresponding to the limiting bead. A set of linkage rods is slidably connected in the linkage groove.

[0009] Preferably, when the outer end of the linkage rod contacts the limiting bead, the other end extends into the slot and contacts the fixed crank arm.

[0010] Preferably, the two ends of the fixed crank arm are of different lengths, and the curved part at the middle end is rotatably connected to the movable groove.

[0011] Preferably, a set of slots is provided at the rear end of the side of the slot near the linkage groove, and a card block is provided inside the slots. The long end of the fixed crank arm is provided with a notch corresponding to the card block.

[0012] Preferably, the top of the top block is hemispherical and contacts the short end of the fixed curved arm.

[0013] Compared with the prior art, the beneficial effects of this utility model are: The connecting mechanism connects the outer pipe to the connecting pipe at the rear end of the nozzle, optimizing the cumbersome and inconvenient installation and disassembly of traditional threaded bolts. It forms a modular disassembly structure, which can effectively improve the efficiency of nozzle installation and disassembly, thus facilitating nozzle cleaning operations. The connecting mechanism includes components such as a moving sleeve, a covering sleeve, a fixed outer ring, a spring, and a locking mechanism. With their cooperation, they can achieve a multi-level sealing and locking effect between the connecting pipe and the outer pipe, effectively improving installation stability and sealing effect. The structure is simple and stable, and has strong practicality. Attached Figure Description

[0014] Figure 1 This is a schematic diagram of the left-side structure of this utility model; Figure 2 This is a left-side view of the connection structure between the connecting pipe and the outer pipe of this utility model; Figure 3 This is a schematic diagram of the internal structure of the movable groove of this utility model; Figure 4 This is a schematic diagram of the limiting bead connection structure of this utility model; Figure 5 for Figure 2 Enlarged structural diagram at point A in the middle.

[0015] In the diagram: Nozzle-1, Connecting pipe-2, Connecting mechanism-3, External pipe-4, Connecting ring-21, Movable groove-22, Fixed crank arm-23, Spring 1-24, Top block-25, Moving sleeve-31, Covering sleeve-32, Fixed outer ring-33, Spring 2-34, Locking mechanism-35, Recycling groove 1-311, Spring 3-312, Limiting bead-313, Slot-351, Linkage groove-352, Linkage rod-353. Detailed Implementation

[0016] To further explain the technical solution of this utility model, a detailed description is provided below through specific embodiments.

[0017] Please see Figure 1-2 This invention provides a nanosphere microcapsule encapsulation device for polypeptide active ingredients, including a nozzle 1, a set of connecting tubes 2 connected to the rear end of the nozzle 1, an outer tube 4 connected to the rear end of the connecting tubes 2, and the front end of the outer tube 4 connected to the connecting tubes 2 through a connecting mechanism 3, which can improve the stability and sealing of the connection.

[0018] Please see Figure 2-3 This invention provides a nanosphere microcapsule encapsulation device for polypeptide active ingredients. A set of connecting rings 21 are fixedly connected to the rear end face of the connecting tube 2. At least two sets of movable grooves 22 are equally spaced on the outer side of the connecting rings 21. A set of fixed curved arms 23 are installed in each movable groove 22. The two ends of the fixed curved arms 23 are of different lengths and are rotatably connected to the movable grooves 22 by the middle curved part. A set of top blocks 25 are connected to the inner side of the movable grooves 22 near the connecting tube 2 by springs 24. The top of the top block 25 is hemispherical and contacts the short end of the fixed curved arm 23, which can push the short end of the fixed curved arm 23 and restrict its rotation direction.

[0019] Please see Figure 2 This utility model provides a nanosphere microcapsule encapsulation device for polypeptide active ingredients. The connecting mechanism 3 includes a movable sleeve 31, a covering sleeve 32, a fixed outer ring 33, a second spring 34, and a locking mechanism 35. A set of movable sleeves 31 is sleeved on the outer front end of the outer tube 4. A set of covering sleeves 32 is fixedly connected to the rear of the movable sleeves 31 near the outer side. The thickness of the covering sleeves 32 is half that of the movable sleeves 31, and they are integrated with the movable sleeves 31. The outer sides of the movable sleeves 31 and the covering sleeves 32 are provided with a frosted layer to improve friction and facilitate force application and movement. A set of fixed outer rings 33 is fixedly connected to the outer front end of the outer tube 4 at the position corresponding to the covering sleeves 32. A set of second springs 34 is provided on the front end face of the fixed outer rings 33. The other end of the second springs 34 is connected to the rear of the movable sleeves 31 near the inner side. Furthermore, the rear end of the covering sleeves 32 extends to the outer front end of the fixed outer rings 33 to cover and protect the fixed outer rings 33 and the second springs 34.

[0020] Please see Figure 4 This utility model provides a nanosphere microcapsule encapsulation device for polypeptide active ingredients. The inner side of the movable sleeve 31 is provided with a recovery groove 311 corresponding to the movable groove 22. The inner end of the recovery groove 311 is connected to a set of limiting beads 313 through spring 312. The end of the limiting beads 313 away from spring 312 can extend to the inner side of the movable sleeve 31.

[0021] Please see Figure 5This invention provides a nanosphere microcapsule encapsulation device for polypeptide active ingredients. The locking mechanism 35 includes a slot 351, a linkage groove 352, and a linkage rod 353. The front end face of the outer tube 4 is provided with a slot 351 corresponding to a connecting ring 21, which can be inserted into the slot 351. The inner side of each slot 351 is provided with a linkage groove 352 corresponding to a limiting bead 313. A set of linkage rods 353 are slidably connected in the linkage groove 352. The length of the linkage rod 353 is greater than the length in the linkage groove 352. When the outer end of the linkage rod 353 contacts the limiting bead 313, the spring 312 can release the spring force. The limiting bead 313 pushes the linkage rod 353 inward. The other end of the linkage rod 353 extends into the slot 351, contacts the short end of the fixed crank arm 23, and compresses the spring 24, causing the fixed crank arm 23 to rotate. Furthermore, a set of slots is provided at the rear end of the side of the slot 351 near the linkage groove 352. A locking block is fixedly connected to the inside of the slot. The long end of the fixed crank arm 23 is provided with a notch corresponding to the locking block. After the fixed crank arm 23 rotates, the long end can move into the slot and connect with the locking block through the notch, thereby locking the connecting ring 21 into the slot 351, realizing the connection between the connecting pipe 2 and the outer pipe 4.

[0022] The working principle is as follows: In use, first apply force to the outside of the movable sleeve 31 and pull it backward to separate the limiting bead 313 from the outer end of the linkage groove 352. Then, insert the connecting ring 21 of the connecting tube 2 into the slot 351. At this time, release the movable sleeve 31, and the spring 2 34 releases its elastic force to push the movable sleeve 31 back to its original position. The limiting bead 313 moves back to the outer end of the linkage groove 352 under the push of the spring 312 and pushes the linkage rod 353 inward. The other end of the linkage rod 353 presses the short end of the fixed crank arm 23, so that the fixed crank arm 23 can rotate. The long end moves into the slot to form a lock, completing the quick installation of the connecting tube 2 and the outer tube 4. If disassembly is required, the movable sleeve 31 can be pulled backward again, and then the connecting ring 21 can be pulled out from the slot 351.

[0023] The above description is merely a preferred embodiment of the present utility model and is not intended to limit the present utility model. Although the present utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. A nanosphere microcapsule encapsulation device for peptide active ingredients, characterized in that: Includes a nozzle (1), the rear end of which is connected to a set of connecting pipes (2), the rear end of which is connected to an external pipe (4), and the front end of the external pipe (4) is connected to the connecting pipe (2) through a connecting mechanism (3); The rear end of the connecting pipe (2) is connected to a set of connecting rings (21). The outer side of the connecting rings (21) is provided with no less than two sets of movable grooves (22) at equal intervals. Each movable groove (22) is provided with a set of fixed crank arms (23). The inner side of the movable groove (22) near the connecting pipe (2) is connected to a set of top blocks (25) by a spring (24).

2. The nanosphere microcapsule encapsulation device for polypeptide active ingredients according to claim 1, characterized in that: The connecting mechanism (3) includes a movable sleeve (31), a covering sleeve (32), a fixed outer ring (33), a second spring (34), and a locking mechanism (35). The outer front end of the outer tube (4) is provided with a set of movable sleeves (31), and a set of covering sleeves (32) is provided at the rear of the movable sleeves (31) near the outer side. The outer front end of the outer tube (4) is provided with a set of fixed outer rings (33) corresponding to the position of the covering sleeves (32). The front end face of the fixed outer rings (33) is provided with a set of second springs (34), and the other end of the second springs (34) is connected to the rear of the movable sleeves (31).

3. The nanosphere microcapsule encapsulation device for polypeptide active ingredients according to claim 2, characterized in that: The inner side of the movable sleeve (31) is provided with a recycling groove (311) corresponding to the movable groove (22), and the inner end of the recycling groove (311) is connected to a set of limiting beads (313) by spring three (312).

4. The nanosphere microcapsule encapsulation device for polypeptide active ingredients according to claim 3, characterized in that: The locking mechanism (35) includes a slot (351), a linkage groove (352) and a linkage rod (353). The front end face of the outer tube (4) is provided with a slot (351) corresponding to the connecting ring (21). The inner side of the slot (351) is provided with a linkage groove (352) corresponding to the limiting bead (313). A set of linkage rods (353) is slidably connected in the linkage groove (352).

5. The nanosphere microcapsule encapsulation device for polypeptide active ingredients according to claim 4, characterized in that: When the outer end of the linkage rod (353) contacts the limiting bead (313), the other end extends into the slot (351) and contacts the fixed crank arm (23).

6. The nanosphere microcapsule encapsulation device for polypeptide active ingredients according to claim 5, characterized in that: The fixed crank arm (23) has different lengths at both ends and is rotatably connected to the movable groove (22) by the middle curved part.

7. The nanosphere microcapsule encapsulation device for polypeptide active ingredients according to claim 6, characterized in that: The slot (351) has a set of card slots on the rear end of the side near the linkage slot (352), and a card block is provided inside the card slot. The long end of the fixed crank arm (23) has a notch corresponding to the card block.

8. The nanosphere microcapsule encapsulation device for polypeptide active ingredients according to claim 6, characterized in that: The top of the top block (25) is hemispherical and contacts the short end of the fixed curved arm (23).

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