An ex vivo tissue sectioning tool

Abstract

The utility model discloses an in vitro tissue section cutter, including cutter body part and blade part, be equipped with the ramp transition portion of connecting cutting area and installation area between the blade part and cutter body part, and this transition portion projects cutter body part surface, and the projection height matches the step difference of tool holder, the blade part and transition portion are equipped with cobalt base alloy combination layer and diamond - tungsten carbide nanometer composite coating from inside to outside in proper order, transition portion is equipped with anti - sticky coating outwardly. The utility model discloses the diamond - tungsten carbide composite coating hardness high, tenacity good, make its use not easy to break and roll blade, and the cobalt base alloy combination layer set not only can promote the combination strength of diamond - tungsten carbide composite coating, not easy to happen interlayer separation, can also block the penetration of chloride ion, thereby slow down the passivation problem of blade because of sterilization and disinfection.

Description

Technical Field

[0001] This utility model relates to the field of medical device technology, and in particular to an ex vivo tissue slicing tool. Background Technology

[0002] In modern medical research, hard tissue sectioning equipment can cut non-demineralized hard tissues such as bone and teeth into thin slices, which can then be stained and used for other medical research activities, playing an important auxiliary role in medical histological research.

[0003] The commonly used hard tissue microtome blades are generally imported from Germany, such as the Leica D-type tungsten carbide blade. This tungsten carbide blade has high hardness but poor toughness, and it is prone to chipping and rolling during use. Once the blade chipps or rolls, it can only be replaced with a new microtome blade, resulting in a lot of waste. In addition, the blades in biological laboratories need to be sterilized before use, and repeated sterilization will also accelerate the dulling of the blades and affect their service life.

[0004] To address these issues, we propose a novel ex vivo tissue sectioning tool. Utility Model Content

[0005] The purpose of this invention is to provide an ex vivo tissue sectioning tool to solve the problems mentioned in the background art.

[0006] To achieve the above objectives, this utility model provides the following technical solution:

[0007] An ex vivo tissue sectioning tool includes a blade body and a blade edge. A sloping transition section connecting the cutting area and the mounting area is provided between the blade edge and the blade body. The transition section protrudes from the surface of the blade body and the protrusion height matches the step drop of the blade holder. The blade edge and the transition section are provided with a cobalt-based alloy bonding layer and a diamond-tungsten carbide nanocomposite coating from the inside to the outside. An anti-stick coating is provided on the outside of the transition section.

[0008] In a further embodiment, the inclination angle of the transition section is 10-20°.

[0009] In a further embodiment, the thickness of the cobalt-based alloy bonding layer is 40-60 μm.

[0010] In a further embodiment, the outer surface of the cobalt-based alloy bonding layer is uniformly distributed with several inverted conical micro-protrusions, and the micro-protrusions interlock with the diamond-tungsten carbide nanocomposite coating.

[0011] In a further embodiment, the thickness of the diamond-tungsten carbide nanocomposite coating is 5-15 μm.

[0012] In a further embodiment, the outer surface of the diamond-tungsten carbide nanocomposite coating is provided with a plurality of fish-scale-shaped micro-pits, the micro-pits having a diameter of 5μm, a depth of 0.8μm, and a spacing of 15μm.

[0013] In a further embodiment, the thickness of the anti-stick coating is 45-75 μm.

[0014] Compared with the prior art, the beneficial effects of this utility model are:

[0015] The diamond-tungsten carbide composite coating of this invention has high hardness and good toughness, making it less prone to chipping and rolling during use. The cobalt-based alloy bonding layer not only enhances the bonding strength of the diamond-tungsten carbide composite coating and prevents interlayer separation, but also blocks chloride ion penetration, thereby mitigating the problem of blade passivation caused by sterilization. In addition, the inclined transition section and anti-stick coating not only eliminate the step difference of the blade holder, but also reduce the friction between the slice and the transition surface, effectively preventing the slice from curling and accumulating at the connection between the blade holder and the blade. Attached Figure Description

[0016] Figure 1 This is a schematic diagram of the structure of this utility model;

[0017] Figure 2 This is a side view cross-sectional structural diagram of the present invention;

[0018] Figure 3 This is a partial side view of the structure of the present invention and the tool holder mounting;

[0019] Figure 4 This is a schematic diagram of the surface structure of the diamond-tungsten carbide nanocomposite coating of this utility model;

[0020] Figure 5 This utility model Figure 2 Enlarged structural diagram at point A in the middle.

[0021] In the figure: 1. Blade body; 2. Blade edge; 3. Transition section; 4. Cobalt-based alloy bonding layer; 41. Micro-protrusion; 5. Diamond-tungsten carbide nanocomposite coating; 51. Micro-pit; 6. Anti-stick coating. Detailed Implementation

[0022] In the description of this utility model, it should be understood that the terms "center," "longitudinal," "lateral," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," and "outer," etc., indicating the orientation or positional relationship, are based on the orientation or positional relationship shown in the accompanying drawings and are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model. In the description of this utility model, unless otherwise stated, "a plurality of" means two or more.

[0023] In the description of this utility model, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "joining" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model based on the specific circumstances.

[0024] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0025] Please see Figure 1-5A scalpel for slicing ex vivo tissue includes a blade body 1, a cutting edge 2, and a transition section 3. The blade body 1, cutting edge 2, and transition section 3 are formed by wire cutting of 440C stainless steel. The height of the transition section 3 protruding from the surface of the blade body 1 matches the step difference of the blade holder, so that after the blade body is installed with the blade holder, the transition section 3 is flush with the surface of the blade holder, thereby reducing tissue accumulation at the junction. The surface of the cutting edge 2 is laser-textured to improve the interlayer bonding strength. Then, CoCrWC powder is deposited on the surface of the cutting edge 2 using chemical vapor deposition to form a 50μm thick cobalt-based alloy bonding layer 4, which can block chloride ion penetration, thereby mitigating the problem of blade passivation due to sterilization. Furthermore, the surface of the cobalt-based alloy bonding layer 4 forms inverted conical micro-protrusions 41. Finally, CH4+H2+W(CO)6 is introduced using CVD technology. A diamond-tungsten carbide composite crystal cluster was obtained by deposition at 850℃ for 2 hours using a mixed gas, forming a 10μm thick diamond-tungsten carbide nanocomposite coating 5. The coating uses 80% diamond to provide hardness and 20% tungsten carbide particles to form a supporting skeleton, solving the brittleness problem of pure diamond coatings and making it less prone to chipping and rolling during use. Micro-protrusions 41 improve the bonding strength between the two coating layers. Fish-scale-like micro-pits 51 with a diameter of 5μm, a depth of 0.8μm, and a spacing of 15μm are processed on the surface of the composite coating 5 by femtosecond laser etching. These pits are used to store lubricant, reduce the friction coefficient of the blade 2 surface, and prevent tissue slices from sticking together. A 60μm thick anti-stick coating 6 is formed by spraying PTFE on the surface of the transition part 3 using plasma spraying technology, which further reduces the friction between the slice and the surface of the transition part 3, allowing the tissue slices to unfold smoothly.

[0026] It will be apparent to those skilled in the art that this invention is not limited to the details of the exemplary embodiments described above, and that it can be implemented in other specific forms without departing from the spirit or essential characteristics of this invention. Therefore, the embodiments should be considered illustrative and non-limiting in all respects, and the scope of this invention is defined by the appended claims rather than the foregoing description. Thus, it is intended that all variations falling within the meaning and scope of equivalents of the claims be included within this invention. No reference numerals in the claims should be construed as limiting the scope of the claims.

[0027] Furthermore, it should be understood that although this specification describes embodiments, not every embodiment contains only one independent technical solution. This narrative style is merely for clarity. Those skilled in the art should consider the specification as a whole, and the technical solutions in each embodiment can also be appropriately combined to form other embodiments that can be understood by those skilled in the art.

Claims

1. A slicing tool for ex vivo tissue, comprising a blade body (1) and a cutting edge (2), characterized in that: The blade part (2) and the blade body part (1) are provided with a sloping transition part (3) connecting the cutting area and the mounting area. The transition part (3) protrudes from the surface of the blade body part (1) and the protrusion height matches the step difference of the blade holder. The blade part (2) is provided with a cobalt-based alloy bonding layer (4) and a diamond-tungsten carbide nanocomposite coating (5) from the inside to the outside. The transition part (3) is provided with an anti-stick coating (6).

2. The ex vivo tissue sectioning tool according to claim 1, characterized in that: The inclination angle of the transition section (3) is 10-20°.

3. The ex vivo tissue sectioning tool according to claim 1, characterized in that: The thickness of the cobalt-based alloy bonding layer (4) is 40-60 μm.

4. The ex vivo tissue sectioning tool according to claim 1, characterized in that: The outer surface of the cobalt-based alloy bonding layer (4) is uniformly distributed with several inverted conical micro-protrusions (41), and the micro-protrusions (41) interlock with the diamond-tungsten carbide nanocomposite coating (5).

5. The ex vivo tissue sectioning tool according to claim 1, characterized in that: The thickness of the diamond-tungsten carbide nanocomposite coating (5) is 5-15 μm.

6. The ex vivo tissue sectioning tool according to claim 5, characterized in that: The outer surface of the diamond-tungsten carbide nanocomposite coating (5) is provided with several fish-scale-shaped micro-pits (51), the diameter of which is 5μm, the depth is 0.8μm, and the spacing is 15μm.

7. The ex vivo tissue sectioning tool according to claim 1, characterized in that: The thickness of the anti-stick coating (6) is 45-75 μm.

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