Pharmaceutical sterile isolator

Abstract

The application discloses a sterile isolator for pharmacy and belongs to the technical field of sterile isolators for pharmacy. The sterile isolator comprises a plug removal processor, a docking bacteria-avoiding assembly is arranged between a docking pipe and an isolating docking outlet, an incomplete spherical structure formed by a bacteria-avoiding block A and a bacteria-avoiding block B can close the exposed surface in contact, effectively blocks the path of external bacteria, and cooperation of an arc-shaped swing groove and a guide rail ensures smooth opening and closing of the bacteria-avoiding block; synchronous swinging of the two bacteria-avoiding blocks is realized through meshing transmission of an incomplete gear and a transmission gear, opening of the channel is ensured through the missing part on the side of the bacteria-avoiding block B, a plug-in structure of a plug block and a plug groove is matched with a limiting column driven by a spring, mechanical limiting is formed during docking, displacement of the bacteria-avoiding block due to vibration or misoperation is prevented, and pollution risks caused by exposure of a docking surface are completely eliminated, so that the stability of a sterile environment in a pharmaceutical process is remarkably improved, and the production quality of medicines is ensured.

Description

Technical Field

[0001] This application relates to the field of sterile isolators for pharmaceutical use, and more specifically, to a sterile isolator for pharmaceutical use. Background Technology

[0002] Rubber stoppers are essential materials for pharmaceutical injection or powder injection production lines. Currently, the connection structure between the discharge port of isolator equipment and the inlet of rubber stopper dispensing barrel on the market is complex and inconvenient to use.

[0003] Existing technology publication CN218839956U discloses a sterile pharmaceutical isolator device for dispensing and packaging. This device includes a rubber stopper processing machine, the outlet of which is sealed to the side of the isolator. It also includes a discharge nozzle and an inlet. The discharge nozzle has a valve at its lower outlet, which connects to a rubber stopper delivery pipe. The lower outlet of the rubber stopper delivery pipe is fitted with an isolator outlet, which has a sealing plug rotating device. The inlet is connected to the isolator connection port via a limiting device, and has another sealing plug rotating device. An inlet is inserted into the isolator connection port, with its lower end connected to a connecting pipe. The lower end of the connecting pipe is connected to an upper pipe of the rubber stopper dispensing container. A sealing plug rotating device is located on one side of the isolator connection port. Device 2 includes a sealing plug rotating device 1 at the inlet end face, a fixing post 1 fixedly installed at the inlet end face, a limiting plate at the upper end of the fixing post 1, a spring 1 sleeved on the outside of the fixing post 1, the spring 1 contacting the lower end face of the limiting plate, a housing sleeved on the outside of the fixing post 1, a limiting component at the lower end of the housing, the upper end of the limiting component inside the housing 1 contacting the lower end of the spring, a sealing plug 1 installed on the outside of the housing 1, a sealing plate at the lower end of the sealing plug matching the inlet opening end face, a handle at the upper end of the housing 1, a limiting plate at the upper end of the fixing post 2, a spring 2 sleeved on the fixing post 2, a housing 2 sleeved on the fixing post 2, a limiting component at the lower end of the housing 2, the upper end of the limiting component contacting the spring 2, the upper end of the spring 2 contacting the lower end of the upper limiting plate of the fixing post 2, and another handle at the upper end of the housing 2.

[0004] Although the existing technical solutions described above can achieve the relevant beneficial effects through the existing technical structure, they still have the following defects: When the sterile isolator for pharmaceutical use is connected to the external structure, the connection surface is exposed, which may lead to bacteria or contamination, which may be brought into the interior and affect the quality of the pharmaceutical product.

[0005] In view of this, we propose a sterile isolator for pharmaceutical use. Utility Model Content

[0006] 1. Technical problems to be solved

[0007] The purpose of this application is to provide a sterile isolator for pharmaceutical use, which solves the technical problem in the above-mentioned background art where, when the sterile isolator is connected to the external structure, bacteria or contaminants are exposed on the connection surface, thus affecting the quality of the pharmaceutical product. This application achieves the desired technical effect.

[0008] 2. Technical Solution

[0009] This application provides a sterile isolator for pharmaceutical use, including...

[0010] A deblocking treatment machine, wherein an isolator is provided on one side of the deblocking treatment machine, an isolating docking outlet is provided on one side of the isolator, and a docking device is provided on one side of the deblocking treatment machine, comprising:

[0011] The connecting pipe is located on one side of the docking equipment;

[0012] A sterilization-avoiding component is provided between the connecting pipe and the isolation docking outlet.

[0013] As an optional solution to the technical solution of this application, the docking antibacterial component includes an antibacterial block A that is oscillatingly disposed inside the docking tube, and an antibacterial block B that is oscillatingly disposed inside the isolation docking outlet;

[0014] The inner wall of the connecting pipe and the isolation docking outlet is provided with a swing groove, and a guide rail is slidably arranged inside the swing groove. The guide rail is fixedly arranged on the outer wall of the antibacterial block B and the antibacterial block A.

[0015] As an optional solution to the technical solution of this application, the antibacterial block B and antibacterial block A form an incomplete spherical structure;

[0016] Both the swing groove and the guide rail are designed with an arc shape.

[0017] As an optional solution to the technical solution of this application, both the antibacterial block B and the antibacterial block A are provided with incomplete gears on their outer walls. The outer walls of the incomplete gears are meshed with transmission gears, and one end of the shaft of the transmission gear extends to the outside and is fixedly provided with a handwheel.

[0018] As an optional solution to the technical solution of this application, two slots are symmetrically opened on the outer wall of the antibacterial block A, and a plug is inserted into the slot. The plug is fixedly set on the outer wall of the antibacterial block B.

[0019] The outer wall of the insert block is provided with a limiting groove, and a limiting post is slidably arranged inside the limiting groove. The limiting post is connected and fixed to the inner wall of the limiting groove by a spring.

[0020] The outer end of the limiting post engages with the limiting groove opened on the inner wall of the slot.

[0021] By adopting the above technical solution, the exposed surface can be sealed by the incomplete spherical structure composed of antibacterial block A and antibacterial block B, effectively blocking the entry path of external bacteria. The cooperation between the arc-shaped swing groove and the guide rail ensures that the opening and closing process of the antibacterial block is smooth and without jamming. The meshing transmission of the incomplete gear and the transmission gear realizes the synchronous swing of the antibacterial blocks on both sides, ensuring that the channel is opened through the missing part on the side of antibacterial block B. The plug-in structure of the plug and the slot, together with the spring-driven limiting post, forms a mechanical limit during docking, preventing the antibacterial block from being displaced due to vibration or misoperation, completely eliminating the risk of contamination caused by the exposure of the docking surface, thereby significantly improving the stability of the aseptic environment in the pharmaceutical process and ensuring the quality of drug production.

[0022] 3. Beneficial effects

[0023] One or more technical solutions provided in this application have at least the following technical effects or advantages:

[0024] This application utilizes an incomplete spherical structure composed of antibacterial block A and antibacterial block B to seal the exposed surface, effectively blocking the entry path of external bacteria. The cooperation between the arc-shaped swing groove and the guide rail ensures a smooth and uninterrupted opening and closing process for the antibacterial blocks. The meshing transmission of the incomplete gear and the drive gear enables the synchronous swinging of the antibacterial blocks on both sides, ensuring that the opening channel is opened through the missing part on one side of antibacterial block B. The insertion structure of the plug and slot, combined with the spring-driven limiting post, forms a mechanical limit during docking, preventing the antibacterial blocks from shifting due to vibration or misoperation, completely eliminating the risk of contamination caused by the exposure of the docking surface. This significantly improves the stability of the aseptic environment in the pharmaceutical process and ensures the quality of drug production. Attached Figure Description

[0025] Figure 1 This is a schematic diagram of the overall structure of a pharmaceutical sterile isolator disclosed in a preferred embodiment of this application;

[0026] Figure 2 This is an exploded view of the docking and sterilization-avoiding component structure of a pharmaceutical sterile isolator disclosed in a preferred embodiment of this application;

[0027] Figure 3 This is a bottom view of the docking and sterilization-avoiding component structure of a pharmaceutical sterile isolator disclosed in a preferred embodiment of this application;

[0028] Figure 4 This is a structurally exploded view of the docking and sterilization-avoiding component of a pharmaceutical sterile isolator disclosed in a preferred embodiment of this application;

[0029] Figure 5 This is a schematic diagram of the structure of sterile block A and sterile block B of a pharmaceutical sterile isolator disclosed in a preferred embodiment of this application;

[0030] The following are the labels in the diagram: 1. Deblocking machine; 2. Isolator; 3. Isolation docking outlet; 4. Docking equipment; 5. Docking pipe; 51. Antibacterial block A; 52. Antibacterial block B; 53. Swing groove; 54. Guide rail; 501. Incomplete gear; 502. Transmission gear; 503. Handwheel; 5001. Slot; 5002. Insert block; 5003. Restriction groove; 5004. Limiting post; 5005. Spring; 5006. Limiting groove. Detailed Implementation

[0031] The present application will be further described in detail below with reference to the accompanying drawings.

[0032] Reference Figures 1-5 This application provides a pharmaceutical sterile isolator, and the technical solution of this application provides a pharmaceutical sterile isolator, including...

[0033] Deblocking treatment machine 1, deblocking treatment machine 1, isolator 2 is provided on one side of deblocking treatment machine 1, isolating docking outlet 3 is provided on one side of isolator 2, docking equipment 4 is provided on one side of deblocking treatment machine 1, including:

[0034] Connector 5 is located on one side of docking equipment 4;

[0035] A sterilization-avoiding assembly is installed between the manifold 5 and the isolation docking outlet 3.

[0036] The antibacterial assembly includes an antibacterial block A51 that is oscillating inside the docking tube 5, and an antibacterial block B52 that is oscillating inside the isolation docking outlet 3;

[0037] The inner wall of the connecting pipe 5 and the isolation docking outlet 3 is provided with a swing groove 53, and a guide rail 54 is slidably arranged inside the swing groove 53. The guide rail 54 is fixedly arranged on the outer wall of the antibacterial block B52 and the antibacterial block A51.

[0038] The antibacterial block B52 and antibacterial block A51 form an incomplete spherical structure;

[0039] Both the swing groove 53 and the guide rail 54 are arranged in an arc shape.

[0040] Both the outer walls of the antibacterial block B52 and the antibacterial block A51 are provided with incomplete gears 501. The outer walls of the incomplete gears 501 are meshed with transmission gears 502. One end of the shaft of the transmission gears 502 extends to the outside and is fixedly provided with a handwheel 503.

[0041] Two slots 5001 are symmetrically opened on the outer wall of the antibacterial block A51. Insertion blocks 5002 are inserted into the slots 5001 and fixedly installed on the outer wall of the antibacterial block B52.

[0042] The outer wall of the insert block 5002 is provided with a limiting groove 5003, and a limiting post 5004 is slidably provided inside the limiting groove 5003. The limiting post 5004 is connected and fixed to the inner wall of the limiting groove 5003 by a spring 5005.

[0043] The outer end of the limiting post 5004 engages with the limiting groove 5006 opened on the inner wall of the slot 5001.

[0044] The incomplete spherical structure composed of antibacterial blocks A and B allows for contact sealing of the exposed surface, effectively blocking the entry path of external bacteria. The cooperation between the arc-shaped swing groove and the guide rail ensures a smooth and uninterrupted opening and closing process for the antibacterial blocks. The meshing transmission of the incomplete gear and the drive gear enables the synchronous swinging of the antibacterial blocks on both sides, ensuring that the channel can be opened through the missing part on the side of antibacterial block B. The insertion structure of the plug and slot, combined with the spring-driven limiting post, forms a mechanical limit during docking, preventing the antibacterial blocks from shifting due to vibration or misoperation, completely eliminating the risk of contamination caused by the exposure of the docking surface. This significantly improves the stability of the aseptic environment in the pharmaceutical process and ensures the quality of drug production.

[0045] Working principle: When using this pharmaceutical sterile isolator, if equipment docking is required, first, contact sterile block A51 and sterile block B52. At this time, the insert 5002 on the outer wall of sterile block B52 is inserted into the slot 5001 of sterile block A51. The limiting post 5004 on the insert 5002 is pushed by the spring 5005 into the limiting groove 5006 on the inner wall of the slot 5001, forming a stable connection. At this time, the docking pipe 5 docks with the isolation docking outlet 3. After docking, rotate the handwheel 503 to drive the transmission gear 502 to rotate. Through the meshing transmission with the incomplete gear 501 on the outer wall of sterile block A51 and sterile block B52, sterile blocks A51 and B52 swing to both sides along the arc trajectory of the swing groove 53. The channel can be opened by passing through the missing part on one side of sterile block B.

Claims

1. A sterile isolator for pharmaceutical use, comprising a decapping machine (1), wherein an isolator (2) is provided on one side of the decapping machine (1), an isolating docking outlet (3) is provided on one side of the isolator (2), and a docking device (4) is provided on one side of the decapping machine (1), characterized in that: Include: The connecting pipe (5) is disposed on one side of the docking equipment (4); A sterilization-avoiding component is provided between the connecting pipe (5) and the isolation docking outlet (3).

2. The pharmaceutical sterile isolator according to claim 1, characterized in that: The docking antibacterial component includes an antibacterial block A (51) that is oscillating inside the docking tube (5), and an antibacterial block B (52) that is oscillating inside the isolation docking outlet (3); The inner wall of the connecting pipe (5) and the isolation docking outlet (3) is provided with a swing groove (53), and a guide rail (54) is slidably arranged inside the swing groove (53). The guide rail (54) is fixedly arranged on the outer wall of the antibacterial block B (52) and the antibacterial block A (51).

3. The pharmaceutical sterile isolator according to claim 2, characterized in that: The antibacterial block B (52) and antibacterial block A (51) form an incomplete spherical structure; Both the swing groove (53) and the guide rail (54) are arranged in an arc shape.

4. The pharmaceutical sterile isolator according to claim 3, characterized in that: Both the antibacterial block B (52) and the antibacterial block A (51) are provided with incomplete gears (501) on their outer walls. The outer walls of the incomplete gears (501) are meshed with transmission gears (502). One end of the shaft of the transmission gears (502) extends to the outside and is fixedly provided with a handwheel (503).

5. The pharmaceutical sterile isolator according to claim 4, characterized in that: Two slots (5001) are symmetrically opened on the outer wall of the antibacterial block A (51), and a plug (5002) is inserted inside the slot (5001). The plug (5002) is fixedly set on the outer wall of the antibacterial block B (52). The outer wall of the insert (5002) is provided with a limiting groove (5003), and a limiting post (5004) is slidably provided inside the limiting groove (5003). The limiting post (5004) is connected and fixed to the inner wall of the limiting groove (5003) by a spring (5005). The outer end of the limiting post (5004) engages with the limiting groove (5006) opened on the inner wall of the slot (5001).

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