An isolator with a folding door

Abstract

The utility model discloses an isolator with folding door, including two operating stations, is provided with folding door between two operating stations in the inside of isolator, the folding door includes two slide rails that set up in parallel up and down, door frame, the sealing strip that is embedded in the door frame, the movable door leaf that sets up in the slide rail, the door leaf one side is the rotating shaft, is close to the inner wall setting of isolator and the door leaf relative this side rotates, the side away from the rotating shaft is the movable shaft, can be movable in the slide rail, the middle of door leaf is hinged together, make movable shaft to rotating shaft close or far away movement, form folding door opening and closing. This folding door plays the sealing, separates the inside of isolator simultaneously, and simultaneously the operation is simple, can deliver larger volume material, has solved the difficult problem of operation of prior art existence, the transmission area is too small, has improved the operation convenience in the isolator.

Description

Technical Field

[0001] This utility model relates to the field of biopharmaceutical manufacturing equipment, specifically to an isolator with a folding door. Background Technology

[0002] Antibody-drug conjugates (ADCs) are small molecule drugs linked to monoclonal antibodies via a chemical chain. The monoclonal antibody then acts as a carrier to target and deliver the drug to target cells. Typically, the small molecule compound used is a highly active compound, and operators should minimize contact with it. Therefore, routine operations such as weighing and adding raw materials must be performed within an isolator. Some isolators have at least two operating positions, each requiring separate sealing during operation. A door inside the isolator that provides isolation can address this issue.

[0003] Patent CN112681947 discloses a double-layer airtight structure for a rat hole door used in isolators. The main function of this rat hole door is to provide a good seal, and its rounded corners reduce the difficulty of cleaning. However, the door is quite thick and heavy, making it inconvenient to operate while wearing gloves.

[0004] Patent CN205532012U discloses a rat hole door structure for an isolator, which adopts a push-pull structure. Although it achieves isolation, in reality, the push-pull door pushes the door on one side to the other side, and the cross-section of the passage is half, which is very inconvenient for passing large volumes of materials.

[0005] Therefore, an isolator with a mouse hole door is needed. This mouse hole door should not be too bulky, nor should it reduce the effective transmission area. Utility Model Content

[0006] To achieve the above-mentioned objectives, this utility model discloses an isolator with a folding door. This folding door not only seals and separates the interior of the isolator, but also is simple to operate and can transfer larger volumes of materials. It solves the problems of operational difficulties and insufficient transfer area in the prior art, and improves the ease of operation in the isolator.

[0007] The purpose of this utility model is to disclose an isolator with a folding door, which includes two operating stations. A folding door is provided inside the isolator and between the two operating stations. The folding door includes two parallel slide rails, a door frame, a sealing strip embedded in the door frame, and a movable door leaf set in the slide rails.

[0008] One side of the door leaf is a rotating shaft, located near the inner wall of the isolator, and the door leaf rotates relative to this side; the side away from the rotating shaft is a movable shaft, which can move within the slide rail. The middle of the door leaves are hinged together, so that the movable shaft moves closer to or away from the rotating shaft, forming the opening and closing of the folding door.

[0009] Compared with the prior art, the large opening design of the folding door of this utility model can meet the needs of large-volume materials, large reactor components, or extra-long feeding tools. Attached Figure Description

[0010] Figure 1 Schematic diagram of the two-operation-station isolator of this utility model;

[0011] Figure 2 A schematic diagram of the folding door of this utility model when closed;

[0012] Figure 3 A schematic diagram of the folding door of this utility model when opened;

[0013] Figure 4 A schematic diagram of the door frame of the folding door of this utility model;

[0014] Figure 5 A schematic diagram of the sealing strip of the folding door of this utility model;

[0015] Figure 6 A schematic diagram of the door panel of this utility model folding door;

[0016] Figure 7 This utility model Figure 2 A magnified view of part A in the image.

[0017] In the diagram, the components are: 1. Operating station; 2. Slide rail; 3. Door frame; 4. Door leaf; 5. Rotating shaft; 6. Moving shaft; 7. Handle; 8. Sealing strip; 9. Return spring; 10. Return spring connection point; and 11. Limit spring. Specific Implementation

[0018] like Figure 1-7 An isolator with a folding door includes two operating stations 1. A folding door is provided inside the isolator and between the two operating stations 1. The folding door includes two parallel slide rails 2, a door frame 3, a sealing strip 8 embedded in the door frame 3, and a movable door leaf 4 provided in the slide rails 2.

[0019] The door leaf 4 has a rotating shaft 5 on one side, which is located near the inner wall of the isolator and the door leaf 4 rotates relative to this side; the side away from the rotating shaft 5 has a movable shaft 6, which can move within the slide rail 2. The middle of the door leaf 4 is hinged together, so that the movable shaft 6 moves closer to or away from the rotating shaft 5, forming the opening and closing of the folding door.

[0020] A return spring connection point 10 is provided on one side of the rotating shaft 5. One end of the return spring 9 is connected to the door leaf 4, and the other end is connected to the inner wall of the isolator.

[0021] A limit spring 11 is provided at one end of the slide rail 2.

[0022] Both the door frame 3 and the sealing strip 8 are deformable.

[0023] A handle 7 is provided on the door leaf 4 near the movable axis 6.

[0024] Working Principle: The isolator has two operating stations 1. One station is used for dispensing or preparing tools, and the other station is used for feeding materials into the reactor. To prevent powder from entering the other station during dispensing, a folding door is installed between the two stations. This includes parallel sliding rails 2, a deformable door frame 3, sealing strips 8, and door panels 4. Axles are installed on the two vertical sides of the door panel 4, with both ends longer than the door panel 4. One end of the axle is inserted into the door frame 3 and can rotate as a rotation axis 5. The other axle has limit protrusions at both ends to prevent it from detaching from the sliding rails 2 when sliding. The door panel 4 is hinged in the middle and can be folded. A return spring 9 is located on the door panel 4, and a limit spring 11 is located in the sliding rails 2 to aid in opening and closing. A handle 7 is provided on the door panel 4 for easy opening.

[0025] Depending on their application, isolators are classified as atmospheric pressure or negative pressure isolators. The folding door of this invention is designed for use under atmospheric pressure.

Claims

1. An isolator with a folding door, comprising two operating stations (1), wherein a folding door is provided inside the isolator and between the two operating stations (1), characterized in that, The folding door includes two parallel slide rails (2), a door frame (3), a sealing strip (8) embedded in the door frame (3), and a movable door leaf (4) set in the slide rails (2). One side of the door leaf (4) is a rotating shaft (5), which is located close to the inner wall of the isolator and the door leaf (4) rotates relative to this side. The side away from the rotating shaft (5) is a movable shaft (6), which can move in the slide rails (2). The middle of the door leaf (4) is hinged together, so that the movable shaft (6) moves closer to or away from the rotating shaft (5) to form the opening and closing of the folding door.

2. The isolator with a folding door according to claim 1, characterized in that, The rotating shaft (5) is provided with a return spring connection point (10) on one side. One end of the return spring (9) is connected to the door leaf (4), and the other end is connected to the inner wall of the isolator.

3. An isolator with a folding door according to claim 2, characterized in that, A limit spring (11) is provided at one end of the slide rail (2).

4. An isolator with a folding door according to claim 3, characterized in that, Both the door frame (3) and the sealing strip (8) are deformable.

5. An isolator with a folding door according to claim 4, characterized in that, A handle (7) is provided on the door leaf (4) near the movable axis (6).

Images