Biological agent sampling device

Abstract

The utility model relates to biological reagent sampling technical field discloses a biological reagent sampling device, including the bottom disc, the bottom disc top fixedly connected with horizontal slide rail seat, the horizontal slide rail seat inside slide connection has horizontal moving frame, the horizontal moving frame top fixedly connected with the adjusting rod, the adjusting rod left side fixedly connected with the rotary hand wheel, the adjusting rod outside slide connection has the sliding movement piece, the sliding movement piece front side fixedly connected with the lifting boom, the lifting boom bottom fixedly connected with the sampling head mounting plate, the bottom disc outside fixedly connected with the auxiliary function assembly. In the utility model, use drive booster, reduce manual operation dependence, make operation more laborsaving, adapt to a variety of containers and sampling needle, have strong compatibility, buffer pad reduces abrasion, reduces maintenance cost, and the accurate control sampling amount and angle make that the recovery rate is stable.

Description

Technical Field

[0001] This utility model relates to the field of biological reagent sampling technology, and in particular to a biological reagent sampling device. Background Technology

[0002] Biological reagents refer to various biologically active or biologically related reagents used in life science research, medical diagnosis, biotechnology, and other fields. Their core function is to provide necessary material support for biological experiments, detection, and analysis. These reagents are diverse in type and properties, and require high standards for purity and activity.

[0003] Existing main biological reagent sampling devices include pipettes, autosamplers, and frozen sample dispensing equipment. Pipettes can accurately measure and transfer small amounts of biological reagents and are often used for cell culture medium addition, reagent preparation, and other operations. Autosamplers can inject samples from microplates and sample vials under high pressure and have multiple cleaning functions to reduce residues to extremely low levels. They are suitable for automatic sampling in analytical instruments such as high performance liquid chromatography. Swab sampling devices are mainly used to collect biological samples from the body surface, oral cavity, wounds, etc., and can also be used for sampling microorganisms from environmental surfaces.

[0004] In actual pipette operation, errors are easily introduced due to differences in pressing speed, angle, and other operational factors, with deviations being more pronounced in micro-volume operations. Different operators have different operating methods, leading to poor repeatability of results. Furthermore, issues such as tip leakage and hand fatigue can further amplify errors. In autosamplers, the autosampler itself requires transfer when dealing with non-standard containers, which may cause contamination or errors. Precision flow paths have poor tolerance to high-viscosity and particulate samples, are prone to clogging, and require long maintenance times and expensive consumables, resulting in high maintenance costs. In swab sampling devices, the fiber structure shows significant differences in adsorption to different samples. Some swabs release nucleases, which can degrade RNA to a large extent in a short time, and incompatible preservation solutions can also lead to the loss of target molecules. Utility Model Content

[0005] To overcome the above deficiencies, this utility model provides a biological reagent sampling device, which aims to improve the problem.

[0006] To achieve the above objectives, the present invention adopts the following technical solution: A biological reagent sampling device includes a chassis. A transverse slide rail is fixedly connected to the top of the chassis. A transverse moving frame is slidably connected inside the transverse slide rail. An adjusting rod is fixedly connected to the top of the transverse moving frame. A rotating handwheel is fixedly connected to the left side of the adjusting rod. A sliding moving block is slidably connected to the outside of the adjusting rod. A lifting rod is fixedly connected to the front of the sliding moving block. A sampling head mounting plate is fixedly connected to the bottom of the lifting rod. Sampling volume adjusting plates are slidably connected to both sides of the sampling head mounting plate. Adjusting plate locking buttons are fixedly connected to the outside of each sampling volume adjusting plate. A sample placement stage is fixedly connected to the top of the chassis. Auxiliary functional components are fixedly connected to the outside of the chassis. As a further description of the above technical solution: The auxiliary function components include a pedal, which is fixedly connected to the front of the chassis. A waste liquid recovery hopper is fixedly connected to the left side of the pedal, and a syringe cleaning box is fixedly connected to the front of the waste liquid recovery hopper. Lateral limit blocks are fixedly connected to the left and right sides of the lateral slide rail, and a spare syringe rack is fixedly connected to the right side of the chassis. As a further description of the above technical solution: The top of the chassis is provided with a platform mounting groove, and a container fixing ring is fixedly connected inside the platform mounting groove. As a further description of the above technical solution: The transverse slide rail is fixedly connected to the bottom of the sample placement platform, and the transverse moving frame is slidably connected to the top of the sample placement platform; As a further description of the above technical solution: The sampling head mounting plate is fixedly connected to a needle adjustment seat, and a needle sleeve is abutted against the bottom of the needle adjustment seat; As a further description of the above technical solution: A sampling needle is fixedly connected to the inner wall of the needle sleeve; As a further description of the above technical solution: A buffer and shock-absorbing pad is fixedly connected to the inner side of the transverse limiting block, and the buffer and shock-absorbing pad is fixedly connected to the inner side of the transverse slide rail seat. As a further description of the above technical solution: A drive booster is fixedly connected to the outside of the rotating handwheel.

[0007] This utility model has the following beneficial effects: 1. In this utility model, the drive booster fixed on the outside of the rotating handwheel can reduce rotational resistance by increasing the lever arm, which greatly reduces the intensity of manual operation and reduces the dependence on the operator's skill level. Combined with the smooth sliding of the transverse moving frame along the transverse slide rail seat and the precise lifting and lowering of the sliding moving block driven by the adjusting rod, the adjustment of the sampling position is more labor-saving, especially suitable for continuous sampling of batch samples.

[0008] 2. In this utility model, the sampling head mounting plate can quickly replace sampling needles of different specifications through the detachable abutment structure of the needle adjustment seat and the needle sleeve. The spare needle tube rack can store spare parts of various models. The container fixing ring in the mounting slot can be flexibly adapted according to the size of the reagent container to achieve stable fixing of various containers such as test tubes and centrifuge tubes, and meet the sampling needs of different biological reagents.

[0009] 3. In this utility model, the inner side of the transverse limiting block on both sides of the transverse slide rail seat is provided with buffer and shock-absorbing pads, which can effectively buffer the impact force when the transverse moving frame slides to the limit position and reduce the mechanical wear of the slide rail and the moving frame; the needle sleeve of the sampling needle can protect the needle body and reduce direct collision. With the regular cleaning of the needle tube cleaning box, the service life of the core components is extended and the frequency of equipment maintenance and replacement is reduced.

[0010] 4. In this utility model, the sampling volume adjustment plates on both sides of the sampling head mounting plate can be slidably positioned and fixed by the adjustment plate locking button to achieve precise control of the sampling volume; the needle adjustment seat can finely adjust the angle of the sampling needle to ensure that the insertion depth and angle are consistent, reduce reagent residue or overflow caused by operation deviation, keep the sample recovery rate stable, and meet the strict requirements of biological experiments for data repeatability. Attached Figure Description

[0011] Figure 1 This is a three-dimensional schematic diagram of a biological reagent sampling device proposed in this utility model; Figure 2 This is a schematic diagram of the sampling head mounting plate structure of a biological reagent sampling device proposed in this utility model; Figure 3 This is a schematic diagram of the adjusting rod structure of a biological reagent sampling device proposed in this utility model; Figure 4 This is a schematic diagram of the sample placement platform structure of a biological reagent sampling device proposed in this utility model; Figure 5 This is a schematic diagram of the sampling needle structure of a biological reagent sampling device proposed in this utility model.

[0012] Legend: 1. Chassis; 2. Lateral slide rail seat; 3. Lateral moving frame; 4. Adjusting rod; 5. Rotary handwheel; 6. Sliding moving block; 7. Lifting rod; 8. Sampling head mounting plate; 9. Needle adjusting seat; 10. Needle sleeve; 11. Sampling needle; 12. Sampling volume adjusting plate; 13. Adjusting plate locking button; 14. Sample placement stage; 15. Stage mounting groove; 16. Container fixing ring; 17. Pedal; 18. Drive booster; 19. Waste liquid recovery hopper; 20. Needle cleaning box; 21. Lateral limit block; 22. Spare needle rack; 23. Buffer shock absorption pad. Detailed Implementation

[0013] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present utility model. Obviously, the described embodiments are only one system embodiment of the present utility model, and not all embodiments. All other embodiments obtained by those skilled in the art based on the embodiments of the present utility model without creative effort are within the protection scope of the present utility model.

[0014] Reference Figures 1-5This utility model provides an embodiment of a biological reagent sampling device, including a chassis 1, which serves as the basic load-bearing component of the entire biological reagent sampling device, providing a stable mounting platform for all other components of the device. It possesses sufficient structural strength to withstand the weight of each component during operation and the forces generated during operation, ensuring that the entire device does not shake or shift during work. It is the core component ensuring the overall stability of the device. A transverse slide rail 2 is fixedly connected to the top of the chassis 1, and a transverse moving frame 3 is slidably connected inside the transverse slide rail 2. The structural design of the transverse slide rail 2 ensures that the transverse moving frame 3 can slide smoothly and steadily along a preset direction, while also constraining the sliding range of the transverse moving frame 3, making the movement of the transverse moving frame 3 more precise and controllable, providing reliable structural support for the lateral adjustment of the sampling position. A series of sampling-related components are supported on the top of the transverse moving frame 3. By sliding on the transverse slide rail 2, the lateral position of the subsequently connected sampling components can be adjusted, thereby meeting the sampling requirements for samples at different lateral positions. An adjusting rod 4 is fixedly connected to the top of the transverse moving frame 3, and a rotating handwheel 5 is fixedly connected to the left side of the adjusting rod 4. This handwheel is the operating component for the operator to control the movement of the sliding moving block 6. By rotating the handwheel 5, the operator can transmit their operating force to the adjusting rod 4, thereby driving the sliding moving block 6 to slide along the adjusting rod 4, achieving precise control of the sampling component's position. Its design is ergonomic, facilitating the application of force by the operator. A sliding moving block 6 is slidably connected to the outside of the adjusting rod 4. A lifting rod 7 is fixedly connected to the front of the sliding moving block 6, and a sampling head mounting plate 8 is fixedly connected to the bottom of the lifting rod 7. The vertical movement of the sliding moving block 6 is transmitted through the lifting rod 7. The sampling head mounting plate 8 is handed over, causing the entire sampling head mounting plate 8 and the components mounted on it to move longitudinally in sync. It is an important intermediate component connecting the sliding moving block 6 and the sampling head mounting plate 8. Sampling volume adjustment plates 12 are slidably connected to both the left and right sides of the sampling head mounting plate 8. The sampling head mounting plate 8 provides a stable installation position for the sampling components. At the same time, it adjusts its overall position as the lifting rod 7 moves, ensuring that the components mounted on it can work together to complete the sampling operation. Adjustment plate locking buttons 13 are fixedly connected to the outer side of the sampling volume adjustment plates 12. A sample placement platform 14 is fixedly connected to the top of the chassis 1. Auxiliary functional components are fixedly connected to the outside of the chassis 1. As an important part of the biological reagent sampling device, the auxiliary functional components form an overall functional support through the coordinated cooperation of various components, providing comprehensive protection for the sampling process.

[0015] Reference Figure 1The auxiliary functional components include a pedal 17. Although it does not directly participate in the core motion transmission of sampling in some connections, it provides a foothold for the operator, helping them maintain balance and stability during operation, indirectly improving the convenience and accuracy of operation. The pedal 17 is fixedly connected to the front of the chassis 1. A waste liquid recovery hopper 19 is fixedly connected to the left side of the pedal 17, mainly used to recover waste liquid generated during sampling. After sampling, when cleaning the sampling needle 11 or treating residual reagents, the waste liquid generated can be directly discharged into the waste liquid recovery hopper 19 for centralized collection and treatment, avoiding indiscriminate flow of waste liquid and pollution, and keeping the device and operating environment clean. A syringe cleaning box 20 is fixedly connected to the front of the waste liquid recovery hopper 19. The syringe cleaning box 20 is used to clean the sampling needle 11. After sampling, the sampling needle 11 is placed in the syringe cleaning box 20 to clean the inner and outer walls of the sampling needle 11, remove residual reagents, prevent cross-contamination between different samples, ensure the accuracy of subsequent sampling, and extend the service life of the sampling needle 11. Lateral limiting blocks 21 are fixedly connected to the left and right sides of the lateral slide rail 2. The lateral limiting blocks 21 restrict the sliding range of the lateral moving frame 3. When the lateral moving frame 3 slides to both ends of the lateral slide rail 2, it will contact the lateral limiting blocks 21, thereby preventing the lateral moving frame 3 from sliding further. A spare syringe rack 22 is fixedly connected to the right side of the chassis 1. The spare syringe rack 22 is used to store spare sampling needles 11. When the sampling needle 11 is damaged or needs to be replaced with a sampling needle 11 of a different specification, the operator can take it from the spare syringe rack 22, which is convenient and quick, improves the continuity of sampling operations, and avoids interruption of operations due to problems with the sampling needle 11.

[0016] Reference Figure 4 The top of the chassis 1 is provided with a mounting groove 15, and a container fixing ring 16 is fixedly connected inside the mounting groove 15. The main function of the mounting groove 15 is to provide an installation position for the container fixing ring 16. The shape and size of the mounting groove 15 match the container fixing ring 16, which can ensure the stability of the container fixing ring 16 after installation and prevent the container fixing ring 16 from shaking or shifting during use, thereby ensuring the stable placement of the sample container. The container fixing ring 16 is used to fix the sample container placed on the sample placement platform 14. Its inner diameter is adapted to the outer diameter of common sample containers, which can firmly fix the sample container in the preset position, avoid the sample container from having an accident during the sampling process, and ensure that the sampling needle 11 can accurately pierce the container for sampling.

[0017] Reference Figure 1 and Figure 4The transverse slide rail 2 is fixedly connected to the bottom of the sample placement platform 14, and the transverse moving frame 3 is slidably connected to the top of the sample placement platform 14. It provides a stable placement space for the sample container. Its surface has an adjustable fixing groove to ensure the stability of the sample container. At the same time, the transverse moving frame 3 slides on its top, allowing the sampling component to move and sample above the sample placement platform 14. It is an important component for carrying the sample.

[0018] Reference Figure 2 The sampling head mounting plate 8 is fixedly connected to the needle adjustment seat 9, and the bottom of the needle adjustment seat 9 abuts against the needle sleeve 10. It mainly serves to support the needle sleeve 10 and make fine adjustments to its position. By making fine adjustments to the needle adjustment seat 9, the angle and position of the needle sleeve 10 can be adjusted to ensure that the sampling component can penetrate the sample container at a suitable angle, thereby improving the accuracy and stability of sampling.

[0019] Reference Figure 5 A sampling needle 11 is fixedly connected to the inner wall of the needle sleeve 10. The needle sleeve 10 protects and fixes the sampling needle 11. It can stably fix the sampling needle 11 in a preset position, preventing the sampling needle 11 from shaking or shifting during the sampling process. At the same time, it forms a buffer between the sampling needle 11 and the needle adjustment seat 9, reducing the direct force on the sampling needle 11 and extending the service life of the sampling needle 11.

[0020] Reference Figure 1 A buffer and shock-absorbing pad 23 is fixedly connected to the inner side of the transverse limiting block 21. The buffer and shock-absorbing pad 23 is fixedly connected to the inner side of the transverse slide rail seat 2. When the transverse moving frame 3 slides to the point where both ends contact the transverse limiting block 21, the buffer and shock-absorbing pad 23 can absorb the impact force generated by the collision, playing a role in buffering and shock absorption, reducing rigid collisions between the transverse moving frame 3 and the transverse limiting block 21, reducing wear on components, and extending the service life of the device. A drive booster 18 is fixedly connected to the outer side of the rotating handwheel 5. The function of the drive booster 18 is to provide assistance to the operator in turning the rotating handwheel 5. By increasing the lever arm, the operator can turn the rotating handwheel 5 with less effort, reducing the intensity of operation. Especially when the rotating handwheel 5 needs to be turned frequently for sampling operations, it can effectively reduce the physical exertion of the operator and improve the operating efficiency.

[0021] Working principle: The sample container is placed on the sample placement platform 14. The transverse moving frame 3 slides inside the transverse slide rail 2, adjusting the sample placement platform 14 to a suitable position, placing it within the appropriate inner area enclosed by the transverse slide rail 2. Then, the sliding moving block 6 moves on the adjusting rod 4, moving the lifting rod 7, sampling head mounting plate 8, needle adjusting seat 9, and needle sleeve 10 to the front of the transverse slide rail 2 and corresponding to the container on the sample placement platform 14. The lifting rod 7 lowers the sampling head mounting plate 8, needle adjusting seat 9, and needle sleeve 10, and the sampling needle 11 inside the needle sleeve 10 contacts the sample and completes sampling. Then, the lifting rod 7 rises back to its original position. If the sample needs to be replaced, the transverse moving frame 3 slides again inside the transverse slide rail 2 to adjust the position of the sample placement platform 14, while the sliding moving block 6 moves the relevant sampling components. If necessary, the above sampling steps are repeated.

[0022] Finally, it should be noted that the above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Although the present utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for the system technical features therein. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. A biological reagent sampling device, comprising a chassis (1), characterized in that: The chassis (1) is fixedly connected to the top of a transverse slide rail seat (2). A transverse moving frame (3) is slidably connected inside the transverse slide rail seat (2). An adjusting rod (4) is fixedly connected to the top of the transverse moving frame (3). A rotating handwheel (5) is fixedly connected to the left side of the adjusting rod (4). A sliding moving block (6) is slidably connected to the outside of the adjusting rod (4). A lifting rod (7) is fixedly connected to the front of the sliding moving block (6). A sampling head mounting plate (8) is fixedly connected to the bottom of the lifting rod (7). Sampling volume adjusting plates (12) are slidably connected to both the left and right sides of the sampling head mounting plate (8). Adjusting plate locking buttons (13) are fixedly connected to the outside of the sampling volume adjusting plates (12). A sample placement platform (14) is fixedly connected to the top of the chassis (1). An auxiliary functional component is fixedly connected to the outside of the chassis (1).

2. The biological reagent sampling device according to claim 1, characterized in that: The auxiliary function components include a pedal (17), which is fixedly connected to the front of the chassis (1). A waste liquid recovery hopper (19) is fixedly connected to the left side of the pedal (17), and a syringe cleaning box (20) is fixedly connected to the front of the waste liquid recovery hopper (19). A transverse limit block (21) is fixedly connected to the left and right sides of the transverse slide rail seat (2), and a spare syringe rack (22) is fixedly connected to the right side of the chassis (1).

3. The biological reagent sampling device according to claim 1, characterized in that: The chassis (1) has a platform mounting groove (15) on top, and a container fixing ring (16) is fixedly connected inside the platform mounting groove (15).

4. The biological reagent sampling device according to claim 1, characterized in that: The transverse slide rail (2) is fixedly connected to the bottom of the sample placement platform (14), and the transverse moving frame (3) is slidably connected to the top of the sample placement platform (14).

5. A biological reagent sampling device according to claim 1, characterized in that: The sampling head mounting plate (8) is fixedly connected to a needle adjustment seat (9), and the bottom of the needle adjustment seat (9) abuts against a needle sleeve (10).

6. A biological reagent sampling device according to claim 5, characterized in that: A sampling needle (11) is fixedly connected to the inner wall of the needle sleeve (10).

7. A biological reagent sampling device according to claim 2, characterized in that: The inner side of the transverse limiting block (21) is fixedly connected to a buffer damping pad (23), which is fixedly connected to the inner side of the transverse slide rail seat (2).

8. A biological reagent sampling device according to claim 1, characterized in that: A drive booster (18) is fixedly connected to the outside of the rotating handwheel (5).

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