A device for detecting helicobacter pylori in feces

Abstract

The utility model discloses a kind of fecal helicobacter pylori detection devices, it is related to medical equipment technical field, including shell, inside is equipped with baffle to be separated into left cavity and right cavity, baffle bottom is equipped with liquid outlet;Hollow column, bottom is connected with rubber disc, left cavity is separated into upper chamber and lower chamber, sample diluent is used for storing in upper chamber, the bottom of hollow column is equipped with multiple filter holes;Sampling stick, can be inserted into hollow column;Left cover plate is connected in the top end opening of left cavity, it is equipped with through-hole;Right cover plate is connected in the top end opening of right cavity, it is equipped with test strip inside;Limiting mechanism, be set on left cover plate, when rubber disc is in first position, upper chamber is not communicated with right cavity, when rubber disc is in second position, upper chamber is communicated with right cavity. The above-mentioned fecal helicobacter pylori detection device solves the technical problem that existing detection device step is complicated, needs to frequently directly view sample, realizes the technical effect that operation is simple, does not need to frequently directly view sample.

Description

Technical Field

[0001] This utility model relates to the field of medical equipment technology, and in particular to a fecal Helicobacter pylori detection device. Background Technology

[0002] Helicobacter pylori infection is closely related to various gastrointestinal diseases, and the convenience and accuracy of its detection methods are crucial for clinical diagnosis and prevention. Currently, among non-invasive tests, fecal antigen testing is listed as an important direction for future development in the "White Paper on the Prevention and Control of Helicobacter pylori Infection" by the Chinese Center for Disease Control and Prevention due to its simplicity and high patient compliance. Existing fecal antigen tests mainly rely on ELISA (Enzyme-Linked Immunosorbent Assay) and colloidal gold immunochromatography: ELISA requires expensive equipment and professional personnel and is easily affected by human factors; although the colloidal gold method does not require complex instruments, it mostly consists of sample processing tubes and test cards, requiring multiple openings for mixing and sample application, which is cumbersome and prone to contamination. At the same time, the continuous exposure of fecal fluid during the test requires frequent direct viewing of the sample, increasing the psychological burden on the user; the sample processing tubes and sample wells are prone to tipping and leakage, requiring gloves to be worn, which is neither hygienic nor portable.

[0003] Therefore, how to provide a fecal Helicobacter pylori detection device that is easy to operate and improves the efficiency of infection screening is a technical problem that needs to be solved by those skilled in the art. Utility Model Content

[0004] The purpose of this invention is to provide a fecal Helicobacter pylori detection device, which solves the technical problems of existing detection devices being cumbersome and requiring frequent direct viewing of samples.

[0005] To achieve the above objectives, this utility model provides a fecal Helicobacter pylori detection device, comprising:

[0006] The outer shell has an internal baffle that divides the outer shell cavity into a left cavity and a right cavity, and the bottom of the baffle has a liquid outlet;

[0007] A hollow column is connected to a rubber disc at its bottom. The rubber disc fits tightly against the inner wall of the left cavity, dividing the left cavity into an upper chamber and a lower chamber. The upper chamber is used to store sample diluent. The bottom outer circumference of the hollow column is provided with multiple filter holes that communicate with the upper chamber.

[0008] A sampling rod can be inserted into the hollow column;

[0009] A left cover plate is sealed to the top opening of the left cavity, and the left cover plate is provided with a through hole for the hollow column to pass through;

[0010] The right cover plate is sealed to the top opening of the right cavity, and a test strip is placed inside the right cavity;

[0011] A limiting mechanism is provided on the left cover plate. The limiting mechanism is used to limit the vertical movement of the hollow column, so that the rubber disk has a first position and a second position. When the rubber disk is in the first position, the upper chamber is not connected to the right chamber. When the rubber disk is in the second position, the upper chamber is connected to the right chamber.

[0012] Preferably, the bottom of the sampling rod is provided with a groove for quantitatively collecting fecal samples.

[0013] Preferably, the outer circumferential surface of the rubber disc is provided with a rubber ring, and the outer circumferential surface of the rubber ring is in close contact with the inner wall of the left cavity.

[0014] Preferably, a desiccant is placed inside the right cavity.

[0015] Preferably, the sealing connection between the left cover plate and the right cover plate and the outer shell is a threaded connection, and a sealing gasket is provided at the connection point.

[0016] Preferably, the top of the sampling rod is provided with a handle, and the outer peripheral surface of the handle can be closely fitted to the inner wall of the hollow column.

[0017] Preferably, the test strip is a colloidal gold immunochromatographic test strip.

[0018] Preferably, the outer shell is a transparent plastic shell.

[0019] Preferably, the limiting mechanism includes:

[0020] A sliding groove is provided on the top of the left cover plate, one side of the sliding groove is connected to the through hole, and a locking block is slidably connected to the sliding groove;

[0021] An elastic element has one end connected to the side wall of the slide groove and the other end connected to the locking block. The outer surface of the hollow column is vertically provided with a locking groove that engages with the locking block. The locking groove has an upper edge and a lower edge. When the lower edge of the locking groove engages with the locking block, the rubber disc is in a first position. When the upper edge of the locking groove engages with the locking block, the rubber disc is in a second position.

[0022] A handle is located at the top of the card block.

[0023] Preferably, the elastic element is a spring.

[0024] Compared to the aforementioned background technology, this utility model provides a fecal Helicobacter pylori detection device. A rubber disc is positioned in the first position. A sampling rod is removed, and sample diluent is added to the hollow column. The user collects a fecal sample using the sampling rod. After collection, the sampling rod is inserted into the hollow column, where the sample diluent and fecal sample mix and are stirred by the sampling rod. The mixed liquid is filtered through a filter hole and enters the upper chamber located outside the hollow column, causing the hollow column to move downwards and the rubber disc to switch from the first position to the second position. At this time, the upper chamber outside the hollow column is connected to the right chamber. The pretreated mixed liquid flows into the right chamber through the outlet and comes into contact with the test strip placed inside the right chamber. The test strip will specifically react with the Helicobacter pylori antigen in the mixed liquid. The user opens the right cover and observes the color change of the test strip to determine whether the sample contains Helicobacter pylori antigen.

[0025] In summary, the fecal Helicobacter pylori detection device provided in this application is compact in structure, easy to operate, and suitable for home self-testing. It eliminates the need for frequent direct viewing of samples, reducing the psychological burden on users. Attached Figure Description

[0026] To more clearly illustrate the technical solutions in the embodiments of this utility model or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on the provided drawings without creative effort.

[0027] Figure 1 This is a schematic diagram of the fecal Helicobacter pylori detection device provided in an embodiment of the present invention;

[0028] Figure 2 for Figure 1 Enlarged diagram of point A in the middle.

[0029] in:

[0030] 1-Outer shell, 2-Baffle, 3-Liquid outlet, 4-Hollow column, 5-Rubber disc, 6-Upper chamber, 7-Lower chamber, 8-Filter hole, 9-Sampling rod, 10-Left cover plate, 11-Right cover plate, 12-Test strip, 13-Groove, 14-Rubber ring, 15-Desiccant, 16-Slide groove, 17-Clamping block, 18-Elastic element, 19-Handle. Detailed Implementation

[0031] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0032] To enable those skilled in the art to better understand the present invention, the present invention will be further described in detail below with reference to the accompanying drawings and specific embodiments.

[0033] See Figure 1 This application provides a fecal Helicobacter pylori detection device, including a shell 1 with an opening at the top, and a baffle 2 that divides the internal space of the shell 1 into a left cavity and a right cavity. The left cavity is mainly used for sample collection, dilution and pretreatment, while the right cavity is used for sample detection. The bottom of the baffle 2 is provided with a liquid outlet 3, which is used to connect the left cavity and the right cavity, so that the pretreated mixed liquid can flow smoothly from the left cavity into the right cavity.

[0034] The bottom of the hollow column 4 is connected to the rubber disc 5. The hollow column 4 is the insertion channel for the sampling rod 9, which allows the user to insert the sampling rod 9 containing the collected fecal sample into the hollow column 4. The rubber disc 5 fits tightly against the inner wall of the left cavity, dividing the left cavity into an upper chamber 6 (the space above the rubber disc 5 in the left cavity) and a lower chamber 7 (the space below the rubber disc 5 in the left cavity). The upper chamber 6 is the space for storing the sample diluent, which can be mixed with the collected fecal sample. The bottom outer circumference of the hollow column 4 is provided with multiple filter holes 8. When the sample and diluent are mixed, the filter holes 8 can remove large particulate impurities in the fecal sample, allowing the mixed liquid to pass through the filter holes 8 and be located outside the hollow column 4. The pore size of the filter holes 8 is between 0.5 mm and 5 mm.

[0035] The left cover plate 10 is sealed to the top opening of the left cavity, thereby ensuring the sealing of the left cavity. The left cover plate 10 is provided with a through hole for the hollow column 4 to pass through. The through hole ensures that the hollow column 4 can move vertically in the left cavity without damaging the sealing of the left cavity.

[0036] The right cover plate 11 is sealed to the top opening of the right cavity, preventing external air, dust, and other impurities from entering the right cavity and ensuring a pure testing environment. A test strip 12 is placed inside the right cavity; the test strip 12 is used to detect Helicobacter pylori antigen in the mixed liquid. When the pretreated mixed liquid flows into the right cavity, it comes into contact with the test strip 12 and reacts, thus yielding the test result.

[0037] The limiting mechanism is located on the left cover plate 10 and is used to limit the vertical movement of the hollow column 4. Through the action of the limiting mechanism, the rubber disc 5 can switch between the first position and the second position.

[0038] When the rubber disc 5 is in the first position, the upper chamber 6 is not connected to the right chamber. At this time, the sample diluent and the collected sample can be fully pretreated in the upper chamber 6, such as by mixing and filtering.

[0039] When the rubber disc 5 is in the second position, the upper chamber 6 is connected to the right chamber. The pretreated mixed liquid can flow smoothly into the right chamber through the outlet 3, come into contact with the test strip 12 and react, thereby completing the detection process.

[0040] Working principle:

[0041] S1. The rubber disk 5 is in the initial position, i.e., the first position. Take out the sampling rod 9 and add the sample diluent into the hollow column 4.

[0042] S2. The user uses sampling stick 9 to collect fecal samples;

[0043] S3. After collection, insert the sampling rod 9 into the hollow column 4. The sample diluent and fecal sample are mixed in the hollow column 4 and stirred by the sampling rod 9. After the mixed liquid is filtered by the filter hole 8, it enters the upper chamber 6 located on the outside of the hollow column 4. The filter hole 8 can effectively remove large particulate impurities in the fecal sample, making the mixed liquid purer.

[0044] S4. Move the hollow column 4 downwards to switch the rubber disc 5 from the initial position (first position) to the second position. At this time, the upper chamber 6 located outside the hollow column 4 is connected to the right chamber. The pretreated mixed liquid flows into the right chamber through the outlet 3 and comes into contact with the test strip 12 placed in the right chamber. The test strip 12 will react specifically with the Helicobacter pylori antigen in the mixed liquid.

[0045] S5. The user opens the right cover 11 and observes the color change of the test strip 12 to determine whether Helicobacter pylori antigen is present in the sample. For example, if a specific color band appears on the test strip 12, it indicates that Helicobacter pylori antigen is present in the sample, meaning that the person being tested may be infected with Helicobacter pylori; otherwise, it indicates that Helicobacter pylori antigen is not detected.

[0046] In summary, the fecal Helicobacter pylori detection device provided in this application is compact in structure, easy to operate, and suitable for home self-testing. It eliminates the need for frequent direct viewing of samples, reducing the psychological burden on users.

[0047] Specifically, the hollow column 4 is a hollow cylinder, and the cross-sectional shape of the outer shell 1 can be square or circular.

[0048] Based on the above embodiments, the bottom of the sampling rod 9 is provided with a plurality of evenly arranged grooves 13. By setting the grooves 13, the height of the sample volume remains consistent each time it is collected, effectively avoiding detection errors caused by too much or too little sample volume, thereby realizing quantitative collection of fecal samples.

[0049] Based on the above embodiment, a rubber ring 14 is bonded to the outer peripheral surface of the rubber disc 5. The outer peripheral surface of the rubber ring 14 is tightly fitted to the inner wall of the left cavity. In other words, the sealing between the rubber ring 14 and the inner wall of the left cavity is improved by setting the rubber ring 14.

[0050] Based on the above embodiments, a desiccant 15 is placed in the right cavity. That is, the desiccant 15 can be a highly active silica gel desiccant. The silica gel desiccant can continuously play a role in maintaining a dry environment in the right cavity, avoiding the humid environment from causing the reagents on the test strip to become damp and deteriorate, thereby affecting the accuracy of the test results.

[0051] Based on the above embodiments, the sealing connection between the left cover plate 10 and the right cover plate 11 and the outer shell 1 is either a threaded connection or a snap-fit ​​connection, and a sealing gasket is provided at the connection point.

[0052] Specifically, if a threaded connection is used, the edges of the left cover plate 10 and the right cover plate 11 are respectively provided with threads that match the corresponding parts of the outer shell 1. When a snap-fit ​​connection is selected, multiple snaps are evenly distributed on the edges of the left cover plate 10 and the right cover plate 11, and a slot is provided at the corresponding position of the outer shell 1. The snaps are barbed structures with a certain degree of elasticity. When installing the cover plate, simply align the snaps on the cover plate with the slots of the outer shell 1, and then gently press the cover plate. The snaps will then snap into the slots due to their own elasticity, achieving a tight connection. The sealing gasket is made of soft and highly elastic rubber material, such as nitrile rubber or silicone rubber. Its material can deform when compressed, tightly filling the tiny gaps at the connection between the cover plate and the outer shell.

[0053] Preferably, the top of the sampling rod 9 is provided with a handle, and the outer peripheral surface of the handle can be closely fitted to the inner wall of the hollow column 4.

[0054] Based on the above embodiments, test strip 12 is a colloidal gold immunochromatographic test strip, and outer shell 1 is a transparent plastic shell.

[0055] Specifically, test strip 12 uses a colloidal gold immunochromatographic test strip, which can quickly and accurately detect Helicobacter pylori antigen in the sample.

[0056] The outer shell 1 is made of transparent plastic. The transparent plastic material has good light transmittance, and users can clearly observe the color development process of the test strip 12 and the flow state of the sample dilution through the outer shell 1.

[0057] Based on the above embodiments, see Figure 2 The limiting mechanism includes a slide groove 16, which is located on the top of the left cover plate 10. One side of the slide groove 16 is connected to a through hole, and a locking block 17 is slidably connected to the slide groove 16. An elastic element 18 is connected at one end to the side wall of the slide groove 16 and at the other end to the locking block 17. The outer surface of the hollow column 4 is vertically provided with a groove that engages with the locking block 17. The groove has an upper edge and a lower edge. When the lower edge of the groove engages with the locking block 17, the rubber disc 5 is in the first position. When the upper edge of the groove engages with the locking block 17, the rubber disc 5 is in the second position. A handle 19 is located at the top of the locking block 17. The elastic element 18 is a spring.

[0058] In other words, the slide 16 is located on the top of the left cover plate 10, and one side of it communicates with the through hole.

[0059] The locking block 17 is slidably connected to the slide groove 16, and the fitting precision with the slide groove 16 is high. The shape of the locking block 17 is adapted to the locking groove on the outer surface of the hollow column 4, and it can be tightly embedded in the locking groove.

[0060] The elastic element 18 is a spring, with one end connected to the side wall of the slide groove 16 and the other end connected to the locking block 17. The spring has good elastic recovery capability. When the locking block 17 slides on the slide groove 16 under the action of external force, the spring will deform accordingly, storing or releasing elastic potential energy. Under normal conditions, the spring will provide a stable force to the locking block 17, enabling it to be held in the appropriate position, and the locking block 17 will engage with the locking groove.

[0061] The outer surface of the hollow column 4 is vertically provided with a slot that engages with the locking block 17. The slot has a clear upper edge and a lower edge. The size and shape of the slot match the locking block 17, ensuring that the locking block 17 can be firmly locked in the slot without loosening or shaking.

[0062] The handle 19 is located at the top of the card block 17 for easy operation by the user. The user can easily control the sliding of the card block 17 on the slide groove 16 by pulling or pushing the handle 19, thereby realizing the insertion and separation of the card block 17 from the card groove.

[0063] When the lower edge of the slot engages with the card block 17, the rubber disc 5 is in the first position, above the liquid outlet 3. At this time, the spring is under a certain compression, which makes the card block 17 tightly engaged with the lower edge of the slot, ensuring the stability of the position of the rubber disc 5 and preventing accidental movement that could lead to leakage of the sample diluent.

[0064] When sample testing is required, the user pulls handle 19 to slide the locking block 17 on the groove 16, thus separating it from the lower edge of the groove. At this time, the spring deforms and stores elastic potential energy. Then, the user pushes the hollow column 4 to move the rubber disc 5 downward. When the rubber disc 5 moves to the second position, the upper edge of the groove is just aligned with the locking block 17. The user releases handle 19, the spring releases elastic potential energy, and pushes the locking block 17 to engage with the upper edge of the groove, thus fixing the rubber disc 5 in the second position. The upper chamber 6 located outside the hollow column 4 is connected to the right chamber. The pretreated mixed liquid flows into the right chamber through the outlet 3 and comes into contact with the test strip 12 placed in the right chamber.

[0065] It should be noted that in this specification, relational terms such as first and second are used only to distinguish one entity from several other entities, and do not necessarily require or imply any such actual relationship or order between these entities.

[0066] This article uses specific examples to illustrate the principles and implementation methods of this utility model. The descriptions of the above embodiments are only for the purpose of helping to understand the method and core ideas of this utility model. It should be noted that for those skilled in the art, several improvements and modifications can be made to this utility model without departing from the principles of this utility model, and these improvements and modifications also fall within the protection scope of the claims of this utility model.

Claims

1. A fecal Helicobacter pylori detection device, characterized in that, include: The outer shell (1) is provided with a baffle (2) to divide the cavity of the outer shell (1) into a left cavity and a right cavity. The bottom of the baffle (2) is provided with a liquid outlet (3). The hollow column (4) is connected to the bottom of a rubber disc (5). The rubber disc (5) is tightly fitted to the inner wall of the left cavity so that the left cavity is divided into an upper chamber (6) and a lower chamber (7). The upper chamber (6) is used to store sample diluent. The bottom outer circumference of the hollow column (4) is provided with multiple filter holes (8) that connect to the upper chamber (6). The sampling rod (9) can be inserted into the hollow column (4); The left cover plate (10) is sealed to the top opening of the left cavity, and the left cover plate (10) is provided with a through hole for the hollow column (4) to pass through; The right cover plate (11) is sealed to the top opening of the right cavity, and a test strip (12) is placed inside the right cavity. A limiting mechanism is provided on the left cover plate (10). The limiting mechanism is used to limit the vertical movement of the hollow column (4) so ​​that the rubber disc (5) has a first position and a second position. When the rubber disc (5) is in the first position, the upper chamber (6) is not connected to the right chamber. When the rubber disc (5) is in the second position, the upper chamber (6) is connected to the right chamber.

2. The fecal Helicobacter pylori detection device according to claim 1, characterized in that, The bottom of the sampling rod (9) is provided with a groove (13), which is used to quantitatively collect fecal samples.

3. The fecal Helicobacter pylori detection device according to claim 2, characterized in that, The outer circumferential surface of the rubber disc (5) is provided with a rubber ring (14), and the outer circumferential surface of the rubber ring (14) is in close contact with the inner wall of the left cavity.

4. The fecal Helicobacter pylori detection device according to claim 1, characterized in that, A desiccant (15) is placed inside the right cavity.

5. The fecal Helicobacter pylori detection device according to claim 1, characterized in that, The left cover plate (10) and the right cover plate (11) are both threadedly connected to the outer shell (1).

6. The fecal Helicobacter pylori detection device according to claim 1, characterized in that, The top of the sampling rod (9) is provided with a hand-held part, and the outer peripheral surface of the hand-held part can be closely attached to the inner wall of the hollow column (4).

7. The fecal Helicobacter pylori detection device according to claim 1, characterized in that, The test strip (12) is a colloidal gold immunochromatographic test strip.

8. The fecal Helicobacter pylori detection device according to claim 1, characterized in that, The outer shell (1) is a transparent plastic shell.

9. A fecal Helicobacter pylori detection device according to any one of claims 1-8, characterized in that, The limiting mechanism includes: A sliding groove (16) is provided on the top of the left cover plate (10). One side of the sliding groove (16) is connected to the through hole. A locking block (17) is slidably connected on the sliding groove (16). The elastic element (18) is connected at one end to the side wall of the slide groove (16) and at the other end to the locking block (17). The outer surface of the hollow column (4) is vertically provided with a slot that engages with the locking block (17). The slot has an upper edge and a lower edge. When the lower edge of the slot engages with the locking block (17), the rubber disc (5) is in the first position. When the upper edge of the slot engages with the locking block (17), the rubber disc (5) is in the second position. A handle (19) is located at the top of the card block (17).

10. The fecal Helicobacter pylori detection device according to claim 9, characterized in that, The elastic element (18) is a spring.

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