A lead generator

Abstract

The utility model relates to the production technical field of isotope especially relates to a lead generator. Including: top cap, collection cylinder and circulation subassembly, the top cap is used to seal the open mouth of collection cylinder, the collection cylinder constitutes the place of collection decay product, and the parent body of decay product lead -212 is fixed in the bottom of top cap, circulation subassembly communicates with collection cylinder, and drives the solvent of absorption lead radioactive material to circulate and enter collection cylinder inside. The generator simple structure can circulate the solvent that can absorb lead radioactive post -material, improves the absorption rate of solvent to lead radioactive post -material.

Description

Technical Field

[0001] This utility model relates to the field of isotope production technology, and in particular to a lead generator. Background Technology

[0002] The applications of radionuclides in the medical field are becoming increasingly widespread, playing a crucial role, particularly in the diagnosis and treatment of cancer. 224Ra is a pure alpha radionuclide with a half-life of 3.63 days, releasing alpha rays with a maximum energy of 5.69 MeV upon decay. In its decay chain, one of 224Ra's daughter nuclides, 212Pb, is a rare lead radioisotope with a half-life of 10.6 hours. In recent years, 212Pb has shown great potential in cancer treatment, particularly in the treatment of pancreatic cancer, ovarian cancer, colon cancer, breast cancer, and prostate cancer. Furthermore, 212Pb can be used in medical imaging, providing important support for disease diagnosis and treatment.

[0003] In practical applications, 212Pb is typically administered to patients via intravenous injection or other methods in the form of a radiopharmaceutical. To achieve precision treatment, 212Pb usually needs to be bound to a chelating agent and further linked to molecules with targeting capabilities, such as monoclonal antibodies, to ensure the drug accurately reaches the lesion site. Therefore, the chemical, microbiological, and radioactive purity of medical-grade 212Pb must meet extremely high standards to ensure its safety and efficacy.

[0004] Furthermore, due to the short half-life of 212Pb (only 10.6 hours), its preparation process must be highly efficient and rapid to meet the time-sensitive requirements of clinical radiopharmaceuticals. This not only poses challenges to separation and purification techniques but also sets higher standards for the automation and operational efficiency of production equipment. Therefore, developing a technology and equipment capable of efficiently and rapidly preparing high-purity 212Pb is of significant practical importance.

[0005] However, the preparation and purification of lead [212Pb] faces many technical challenges. Traditional radionuclide separation methods usually rely on techniques such as chemical precipitation, solvent extraction, or single resin column adsorption, which suffer from low separation efficiency, complex operation steps, and long production cycles.

[0006] To address these issues, researchers have been exploring more efficient techniques for radionuclide separation and purification. Therefore, developing a radionuclide generator capable of efficient, continuous, and automated operation has become a current research focus.

[0007] The lead [212Pb] generator of this invention was proposed against this background. By using an air carrier gas to collect radioactive 220Rn and then collecting lead [212Pb] after its decay, efficient separation and purification of lead [212Pb] is achieved, providing a reliable technical means for the production of medical radionuclides. Therefore, this problem urgently needs to be solved.

[0008] The above content is only used to help understand the technical solution of this utility model and does not represent an admission that the above content is the closest prior art. Utility Model Content

[0009] The technical problem to be solved by this utility model is to provide a lead generator with a simple structure that can circulate the solvent that absorbs lead-radiated substances, thereby improving the absorption rate of the solvent on lead-radiated substances.

[0010] To achieve the aforementioned objective, the technical solution of this utility model is implemented as follows: a lead generator includes a top cover, a collection cylinder, and a circulation assembly; the top cover is used to seal the opening of the collection cylinder; the collection cylinder constitutes a place for collecting decay products, and the parent body of the decay product lead-212 is fixed at the bottom of the top cover; the circulation assembly is connected to the collection cylinder and drives the solvent that absorbs lead radioactive substances to circulate into the interior of the collection cylinder.

[0011] Preferably, it also includes a fixing part; the fixing part is used to store the lead-212 matrix and is detachably connected to the top cover, and the fixing part is located above the solvent in the collection cylinder.

[0012] Preferably, it also includes a base; the base is used to fix the collection cylinder and forms a detachable connection with the collection cylinder.

[0013] Preferably, the circulation assembly includes an outlet pipe, an inlet pipe, and a circulation pump; one end of the outlet pipe is connected to the middle of the collection cylinder, and the other end is connected to the inlet pipe; the inlet pipe is connected to the bottom of the collection cylinder; the circulation pump is located in the middle of the outlet pipe and is used to circulate and transport the solvent in the collection cylinder along the outlet pipe and the inlet pipe.

[0014] Preferably, a three-way valve is provided at the connection between the water outlet pipe and the water inlet pipe, and one outlet of the three-way valve constitutes the outlet of the solvent inside the collection cylinder.

[0015] Preferably, the fixing part includes a connecting cover and a hollow cylinder; the bottom end of the connecting cover is threadedly connected to the hollow cylinder, and the top end of the connecting cover is threadedly connected to the bottom end of the top cover; the hollow cylinder is used to hold the lead-212 matrix, and the hollow cylinder is provided with holes for lead radioactive materials to escape.

[0016] Preferably, the bottom surface of the collecting cylinder is a conical surface, and the lowest point of the conical surface is connected to the water inlet pipe.

[0017] Preferably, the connection between the top cover and the collecting cylinder is provided with a sealing element for sealing the gap between the top cover and the collecting cylinder.

[0018] Preferably, the sealing element includes a soft rubber pad and a sealing ring; the soft rubber pad is disposed at the bottom of the top cover; the sealing ring is disposed on the inner wall of the side of the top cover and is fitted and connected to the outer wall of the top of the collecting cylinder.

[0019] Preferably, it also includes a counterweight; the counterweight is disposed on the top of the top cover.

[0020] The beneficial effects of this utility model are reflected in:

[0021] The lead generator provided by this utility model improves the absorption rate of lead reactants by driving the solvent circulation inside the collection cylinder, thereby making it convenient for operators to access the product at any time and improving the working efficiency of the collection cylinder. Attached Figure Description

[0022] Figure 1 This is a schematic diagram of the structure of this utility model;

[0023] Figure 2 This is a schematic diagram of the structure of the fixing part of this utility model;

[0024] Figure 3 This is a schematic diagram of the structure of the connecting cover of this utility model;

[0025] Figure 4 This is a schematic diagram of the hollowed-out cylinder of this utility model.

[0026] Explanation of reference numerals in the attached figures:

[0027] 10. Top cover; 11. Counterweight; 12. Cover body; 13. Soft rubber pad; 14. Sealing ring; 20. Fixing part; 21. Connecting cover; 211. Connecting bolt; 212. Internal thread; 22. Hollowed-out cylinder; 221. External thread; 30. Collection cylinder; 31. Conical surface; 41. Water outlet pipe; 42. Water inlet pipe; 43. Circulation pump; 44. Three-way valve; 50. Base. Detailed Implementation

[0028] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only a part of the embodiments of the present utility model, and not all of them. Unless otherwise specified, the embodiments and features in the embodiments of this application can be combined with each other. Based on the embodiments of the present utility model, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present utility model.

[0029] Example

[0030] See Figure 1-4 As shown:

[0031] This invention provides a lead generator, comprising: a top cover 10, a collection cylinder 30, and a circulation assembly. In specific applications, the top cover 10 is used to seal the opening of the collection cylinder 30; the collection cylinder 30 constitutes a place for collecting decay products, and the parent body of the decay product lead-212 is fixed at the bottom of the top cover 10; the circulation assembly is connected to the collection cylinder 30 and drives the solvent that absorbs lead radioactive material to circulate into the collection cylinder 30.

[0032] With this setup, the radioactive material produced after the reaction of lead-212 can dissolve in the solvent, and as the solvent continues to flow, the specific surface area of ​​the solvent increases, thereby increasing the absorption rate of the radioactive material produced by the lead-212 parent material.

[0033] It also includes a fixing part 20; the fixing part 20 is used to store the lead-212 matrix and is detachably connected to the cover 12 of the top cover 10, and the fixing part 20 is located above the solvent in the collection cylinder 30. The fixing part 20 includes a connecting cover 21 and a hollow cylinder 22. The inner wall of the side of the connecting cover 21 is provided with an internal thread 212, and the outer wall of the top of the hollow cylinder 22 is provided with an external thread 221, so that the bottom end of the connecting cover 21 and the hollow cylinder 22 are threadedly connected. The top end of the connecting cover 21 is provided with a connecting bolt 211, and the bottom of the top cover 10 is provided with a bolt groove that forms a threaded connection with the connecting bolt 211, so that the bottom end of the connecting cover 21 and the top cover 10 are threadedly connected.

[0034] In practical applications, the hollow tube 22 is used to hold the lead-212 matrix, and the hollow tube 22 is provided with holes for the radiation generated by the lead-212 matrix.

[0035] It also includes a base 50; the base 50 is used to fix the collection cylinder 30 and forms a detachable connection with the collection cylinder 30. In specific applications, a conical groove is provided on the base 50, and the collection cylinder 30 is inserted into the conical groove.

[0036] The circulation assembly includes an outlet pipe 41, an inlet pipe 42, and a circulation pump 43.

[0037] One end of the outlet pipe 41 is connected to the middle of the collection cylinder 30, and the other end is connected to the inlet pipe 42. The inlet pipe 42 is connected to the bottom of the collection cylinder 30; the circulation pump 43 is located in the middle of the outlet pipe 41 and is used to circulate and transport the solvent in the collection cylinder 30 along the outlet pipe 41 and the inlet pipe 42.

[0038] A three-way valve 44 is provided at the connection between the outlet pipe 41 and the inlet pipe 42, and one outlet of the three-way valve 44 constitutes the outlet of the solvent inside the collection cylinder 30. In practical application, the operator only needs to rotate the manual valve handle on the three-way valve 44 to allow the solvent containing the radioactive material generated by the lead-212 parent material in the collection cylinder 30 to flow out.

[0039] The bottom surface of the collecting cylinder 30 is set as a conical surface 31, and the lowest point of the bottom surface is connected to the water inlet pipe 42, so that the solvent can flow out easily when taking liquid.

[0040] A sealing element is provided at the connection between the top cover 10 and the collection cylinder 30 to seal the gap between the top cover 10 and the collection cylinder 30.

[0041] The sealing element includes a soft rubber gasket 13 and a sealing ring 14; the soft rubber gasket 13 is disposed at the bottom of the top cover 10.

[0042] It also includes a counterweight 11; the counterweight 11 is located on top of the cover 12 of the top cover 10.

[0043] In practical applications, the weight of the counterweight 11 causes the soft rubber pad 13 to fit tightly against the circumference of the collecting cylinder 30, improving the sealing effect. The sealing ring 14 is set on the inner wall of the cover 12 of the top cover 10 and fits against the outer wall of the top of the collecting cylinder 30, thus achieving a double seal, further improving the sealing effect, preventing gas from escaping from the lead generator, and improving the safety of the equipment.

[0044] It should be noted that if the embodiments of this utility model involve directional indicators such as up, down, left, right, front, back, etc., these directional indicators are only used to explain the relative positional relationship and movement of the components in a specific posture as shown in the attached drawings. If the specific posture changes, the directional indicators will also change accordingly. Furthermore, if the embodiments of this utility model involve descriptions such as "first," "second," etc., these descriptions are for descriptive purposes only and should not be construed as indicating or implying their relative importance or implicitly specifying the number of indicated technical features. Therefore, features defined with "first" or "second" can explicitly or implicitly include at least one of those features. Additionally, the meaning of "and / or" throughout the text includes three parallel solutions. Taking "A and / or B" as an example, it includes solution A, solution B, or a solution where A and B are simultaneously satisfied. Furthermore, "multiple" refers to two or more. Furthermore, the technical solutions of the various embodiments can be combined with each other, but this must be based on the ability of those skilled in the art to implement them. When the combination of technical solutions is contradictory or cannot be implemented, it should be considered that such combination of technical solutions does not exist.

[0045] The above are merely preferred embodiments of the present utility model and are not intended to limit the present utility model. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model shall be included within the protection scope of the present utility model.

Claims

1. A lead generator, characterized in that, include: The top cover (10), the collection cylinder (30), and the circulation assembly are provided. The top cover (10) is used to seal the opening of the collection cylinder (30). The collection cylinder (30) constitutes a place for collecting decay products, and the parent body of the decay product lead-212 is fixed at the bottom of the top cover (10). The circulation assembly is connected to the collection cylinder (30) and drives the solvent that absorbs lead radioactive material to circulate into the collection cylinder (30).

2. A lead generator according to claim 1, characterized in that, It also includes a fixing part (20); the fixing part (20) is used to store the lead-212 matrix and is detachably connected to the top cover (10), and the fixing part (20) is located above the solvent in the collection cylinder (30).

3. A lead generator according to claim 1 or 2, characterized in that, It also includes a base (50); the base (50) is used to fix the collection tube (30) and forms a detachable connection with the collection tube (30).

4. A lead generator according to claim 3, characterized in that, The circulation assembly includes an outlet pipe (41), an inlet pipe (42), and a circulation pump (43); one end of the outlet pipe (41) is connected to the middle of the collection cylinder (30), and the other end is connected to the inlet pipe (42); the inlet pipe (42) is connected to the bottom of the collection cylinder (30); the circulation pump (43) is located in the middle of the outlet pipe (41) and is used to circulate and transport the solvent in the collection cylinder (30) along the outlet pipe (41) and the inlet pipe (42).

5. A lead generator according to claim 4, wherein, A three-way valve (44) is provided at the connection between the water outlet pipe (41) and the water inlet pipe (42), and one outlet of the three-way valve (44) constitutes the outlet of the solvent inside the collection cylinder (30).

6. A lead generator according to claim 2, characterized in that, The fixing part (20) includes a connecting cover (21) and a hollow cylinder (22); the bottom end of the connecting cover (21) is threadedly connected to the hollow cylinder (22), and the top end of the connecting cover (21) is threadedly connected to the bottom end of the top cover (10); the hollow cylinder (22) is used to place the lead-212 matrix, and the hollow cylinder (22) is provided with holes for lead radioactive materials to emanate.

7. A lead generator according to claim 6, characterized in that, The bottom surface of the collection tube (30) is a conical surface (31), and the lowest point of the conical surface (31) is connected to the water inlet pipe (42).

8. A lead generator according to claim 6, characterized in that, The connection between the top cover (10) and the collection cylinder (30) is provided with a sealing element for sealing the gap between the top cover (10) and the collection cylinder (30).

9. A lead generator according to claim 8, wherein, The sealing element includes a soft rubber pad (13) and a sealing ring (14); the soft rubber pad (13) is disposed at the bottom of the top cover (10); the sealing ring (14) is disposed on the inner wall of the side of the top cover (10) and is attached to the outer wall of the top of the collecting cylinder (30).

10. A lead generator according to claim 9, characterized in that, It also includes a counterweight (11); the counterweight (11) is disposed on the top of the top cover (10).

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