Cerebral ischemia animal behavior testing device

Abstract

The utility model discloses a cerebral ischemia animal behavior detection device, including vertical storehouse, platform, sliding table and dark box, the platform and sliding table all are fixedly connected in vertical storehouse outer wall, the one side fixedly connected with support of sliding table away from vertical storehouse. In the application, the experimental mouse falling from the balance beam will enter the sliding table and slide along the sliding table to the inside of the barrel composed of the transfer barrel and the sealing plate, then the driving part drives the transmission rod to rotate, the transmission rod drives the screw sleeve and the barrel to go up by screwing with the screw sleeve, the sealing plate contacts the convex edge first, the transfer barrel continues to go up, the connecting sleeve and the polished rod slide and compress the spring until the carrier and the inner wall of the bottom of the transfer barrel are flush, at this time, the experimental mouse can move from the transfer barrel to the platform smoothly, which not only limits the position of the experimental mouse after being guided out of the sliding table, but also ensures the connectivity between the transfer barrel and the platform, thereby improving the stability of the cerebral ischemia animal behavior detection device.

Description

Technical Field

[0001] This utility model relates to the field of detection equipment technology, and in particular to a device for detecting the behavior of animals with cerebral ischemia. Background Technology

[0002] Cerebrovascular diseases are among the top five causes of death, with extremely poor prognoses, especially ischemic stroke. With a rapidly aging population, the problem of ischemic stroke is becoming increasingly serious. However, treatment methods for ischemic stroke still require further exploration. Research on a disease relies on basic experimental work; therefore, ischemic stroke models are crucial. The establishment of ischemic stroke models and the evaluation of treatment efficacy require behavioral and histological methods for verification. The balance beam test is a classic behavioral method for ischemic stroke.

[0003] Chinese Patent Publication No. CN221488703U, published on August 9, 2024, discloses a behavioral detection device for animals with cerebral ischemia, comprising: a base; a support plate, the bottom of which is fixed to the top of the base, and a dark box with a shooting function fixedly connected to the top of the support plate; and a mounting box, the bottom of which is fixed to the top of the base, a platform for carrying experimental mice fixedly connected to the left side of the mounting box, a balance beam fixedly connected between the left side of the platform and the right side of the dark box, and an inclined sliding platform fixedly connected to the top of the base, the sliding platform being located directly below the balance beam.

[0004] Existing behavioral testing devices for animals with cerebral ischemia use a sliding platform to catch falling mice. The mice slide onto a cylindrical moving platform, which is then raised to the platform position by a lifting component. In practice, the moving platform has an open-top cylindrical structure, and after the platform is raised to the platform height, the mice often cannot easily climb out. Therefore, there is an urgent need to develop a corresponding behavioral testing device for animals with cerebral ischemia to solve the above problems. Utility Model Content

[0005] The purpose of this invention is to provide a behavioral detection device for animals with cerebral ischemia in order to solve the above-mentioned problems.

[0006] To achieve the above objectives, the present invention adopts the following technical solution:

[0007] A behavioral testing device for animals with cerebral ischemia includes a vertical chamber, a platform, a sliding table, and a dark box. The platform and the sliding table are fixedly connected to the outer wall of the vertical chamber. A support is fixedly connected to the side of the sliding table away from the vertical chamber. The support is fixedly connected to the platform via a balance beam. The dark box is detachably connected to the top of the balance beam. The vertical chamber integrates a transfer barrel and a lifting assembly for raising and lowering the transfer barrel. The outer side of the transfer barrel integrates a sealing plate and an elastic assembly for maintaining the sealing plate. A protruding edge is fixedly connected to the inner wall of the vertical chamber.

[0008] Preferably, a sliding sleeve is fixedly connected to the outer wall of the dark box, and a fixing part for fixing the sliding sleeve to the balance beam is integrated on the top of the sliding sleeve.

[0009] Preferably, the fixing part includes a positioning rod that is screwed into the top of the sliding sleeve, and the open end of the positioning rod abuts against the top of the balance beam.

[0010] Preferably, the lifting assembly includes a driving component fixedly connected to the inner wall of the vertical compartment, a transmission rod fixedly connected to the output end of the driving component, and a threaded sleeve fixedly connected to the outer wall of the transmission rod and the outer wall of the transfer barrel.

[0011] Preferably, an L-shaped partition is fixedly connected to the inner wall of the vertical compartment, and the horizontal end of the threaded sleeve is slidably connected to the inner wall of the composite plate through a vertically set sliding groove.

[0012] Preferably, the elastic component includes a smooth rod and a connecting sleeve that are fixedly connected to the transfer barrel and the sealing plate respectively. The inner wall of the connecting sleeve is slidably connected to the outer wall of the smooth rod, and a spring is fixedly connected between the bottom of the connecting sleeve and the inner wall of the transfer barrel.

[0013] In summary, due to the adoption of the above technical solution, the beneficial effects of this utility model are:

[0014] 1. In this application, the experimental mouse that falls from the balance beam enters the slide and slides along the slide until it enters the barrel body composed of the transfer barrel and the sealing plate. Then, the drive component drives the transmission rod to rotate. The transmission rod drives the screw sleeve and the barrel body to move upward through the screw engagement with the screw sleeve. The sealing plate first contacts the convex edge, and the transfer barrel continues to move upward. The connecting sleeve slides and engages with the smooth rod and compresses the spring until the carrier is flush with the inner surface of the bottom of the transfer barrel. At this time, the experimental mouse can move smoothly from the transfer barrel to the platform. This not only restricts the position of the experimental mouse after it is taken out from the slide, but also ensures the connectivity between the transfer barrel and the platform, thereby improving the stability of the use of the cerebral ischemia animal behavior detection device.

[0015] 2. In this application, the dark box is moved so that both the dark box and the sliding sleeve slide along the balance beam until the dark box corresponds to a suitable horizontal position. Then, the positioning rod is rotated to screw it into the top of the sliding sleeve. The positioning of the sliding sleeve and the dark box is achieved through the contact friction between the open end of the positioning rod and the balance beam. This allows the distance between the dark box and the platform to be adjusted according to the usage requirements, thereby improving the applicability of the cerebral ischemia animal behavior detection device. Attached Figure Description

[0016] Figure 1 A schematic diagram of the overall structure according to an embodiment of the present utility model is shown;

[0017] Figure 2 A schematic diagram of a sliding sleeve structure according to an embodiment of the present invention is shown;

[0018] Figure 3 A schematic diagram of the convex edge structure provided according to an embodiment of the present utility model is shown;

[0019] Figure 4 A schematic diagram of a spring structure according to an embodiment of the present invention is shown.

[0020] Legend:

[0021] 1. Stand; 2. Support frame; 3. Balance beam; 4. Slide table; 5. Platform; 6. Dark box; 7. Sliding sleeve; 8. Positioning rod; 9. Protruding edge; 10. Transfer barrel; 11. Sealing plate; 12. Transmission rod; 13. Connecting sleeve; 14. Smooth rod; 15. Spring. Detailed Implementation

[0022] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those skilled in the art without creative effort are within the protection scope of the present utility model.

[0023] Please see Figure 1-4 This utility model provides a technical solution:

[0024] The behavioral testing device for animals with cerebral ischemia includes a vertical chamber 1, a platform 5, a sliding table 4, and a dark box 6. The platform 5 and the sliding table 4 are both fixedly connected to the outer wall of the vertical chamber 1. A support 2 is fixedly connected to the side of the sliding table 4 away from the vertical chamber 1. The support 2 is fixedly connected to the platform 5 through a balance beam 3. The dark box 6 is detachably connected to the top of the balance beam 3. The vertical chamber 1 integrates a transfer barrel 10 and a lifting component for raising and lowering the transfer barrel 10. The outer side of the transfer barrel 10 integrates a sealing plate 11 and an elastic component for maintaining the sealing plate 11. A protruding edge 9 is fixedly connected to the inner wall of the vertical chamber 1.

[0025] The experimental mouse that falls from the balance beam 3 will enter the slide table 4 and slide along the slide table 4 until it enters the barrel body composed of the transfer barrel 10 and the sealing plate 11. Then, the driving component drives the transmission rod 12 to rotate. The transmission rod 12 drives the screw sleeve and the barrel body to move upward through the screw sleeve. The sealing plate 11 first contacts the convex edge 9. The transfer barrel 10 continues to move upward. The connecting sleeve 13 slides and engages with the light rod 14 and compresses the spring 15 until the platform 5 is flush with the bottom inner wall of the transfer barrel 10. At this time, the experimental mouse can move smoothly from the transfer barrel 10 to the platform 5. This not only restricts the position of the experimental mouse after it is taken out from the slide table 4, but also ensures the connectivity between the transfer barrel 10 and the platform 5, thereby improving the stability of the use of the cerebral ischemia animal behavior detection device.

[0026] It should be noted that the detection process and principle here are directly based on existing technology, and the structure of the platform 5, balance beam 3 and dark box 6 has not been adjusted. Therefore, the specific detection principle will not be described in detail here.

[0027] Specifically, such as Figure 2 and Figure 4 As shown, a sliding sleeve 7 is fixedly connected to the outer wall of the dark box 6. The top of the sliding sleeve 7 is integrated with a fixing part for fixing the sliding sleeve 7 and the balance beam 3. The fixing part includes a positioning rod 8 that is screwed into the top of the sliding sleeve 7, and the open end of the positioning rod 8 abuts against the top of the balance beam 3. The dark box 6 is moved horizontally so that both the dark box 6 and the sliding sleeve 7 slide along the balance beam 3 until the dark box 6 corresponds to a suitable horizontal position. Then, the positioning rod 8 is rotated to screw into the top of the sliding sleeve 7. The positioning of the sliding sleeve 7 and the dark box 6 is achieved by the contact friction between the open end of the positioning rod 8 and the balance beam 3. In this way, the distance between the dark box 6 and the platform 5 can be adjusted according to the usage requirements, thereby improving the applicability of the brain ischemia animal behavior detection device.

[0028] Specifically, such as Figure 2 and Figure 3 As shown, the lifting assembly includes a driving component fixedly connected to the inner wall of the vertical chamber 1. A transmission rod 12 is fixedly connected to the output end of the driving component. A threaded sleeve fixedly connected to the outer wall of the transmission rod 12 is screwed onto the outer wall of the transfer barrel 10. The driving component drives the transmission rod 12 to rotate. The transmission rod 12 drives the threaded sleeve and the barrel to move upward through the screwing with the threaded sleeve. An L-shaped partition is fixedly connected to the inner wall of the vertical chamber 1. The horizontal end of the threaded sleeve is slidably connected to the inner wall of the partition through a vertically set sliding groove, thereby limiting the axial deflection of the threaded sleeve. The elastic component includes a smooth rod 14 and a connecting sleeve 13 fixedly connected to the transfer barrel 10 and the sealing plate 11, respectively. The inner wall of the connecting sleeve 13 is slidably connected to the outer wall of the smooth rod 14. A spring 15 is fixedly connected between the bottom of the connecting sleeve 13 and the inner wall of the transfer barrel 10, maintaining the relative position of the sealing plate 11 and the transfer barrel 10 while retaining the vertical extension and retraction characteristics of the sealing plate 11.

[0029] Working principle: The experimental mouse falling from the balance beam 3 will enter the slide table 4 and slide along the slide table 4 until it enters the barrel body composed of the transfer barrel 10 and the sealing plate 11. Then, the drive component drives the transmission rod 12 to rotate. The transmission rod 12, through its engagement with the screw sleeve, drives the screw sleeve and the barrel body to move upward. The sealing plate 11 first contacts the convex edge 9. The transfer barrel 10 continues to move upward. The connecting sleeve 13 slides and engages with the smooth rod 14, compressing the spring 15, until the platform 5 is flush with the bottom inner wall of the transfer barrel 10. At this point, the experimental mouse can move smoothly from the transfer barrel 10 to the platform 5, thus restricting the experimental mouse from being guided from the slide table 4. The position after exiting ensures the connectivity between the transfer tank 10 and the platform 5, thereby improving the stability of the brain ischemia animal behavior detection device. The dark box 6 is moved so that both the dark box 6 and the sliding sleeve 7 slide along the balance beam 3 until the dark box 6 corresponds to the appropriate horizontal position. Then, the positioning rod 8 is rotated to screw it into the top of the sliding sleeve 7. The sliding sleeve 7 and the dark box 6 are positioned by the contact friction between the open end of the positioning rod 8 and the balance beam 3. In this way, the distance between the dark box 6 and the platform 5 can be adjusted according to the usage requirements, thereby improving the applicability of the brain ischemia animal behavior detection device.

[0030] The above description of the embodiments enables those skilled in the art to make or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the general principles defined herein may be implemented in other embodiments without departing from the spirit or scope of the present invention. Therefore, the present invention is not to be limited to the embodiments shown herein, but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.

Claims

1. A behavioral testing device for animals with cerebral ischemia, comprising a vertical chamber (1), a stage (5), a sliding stage (4), and a dark box (6), characterized in that, The platform (5) and the slide (4) are both fixedly connected to the outer wall of the vertical compartment (1). The slide (4) is fixedly connected to a bracket (2) on the side away from the vertical compartment (1). The bracket (2) is fixedly connected to the platform (5) through a balance beam (3). The dark box (6) is detachably connected to the top of the balance beam (3). The vertical compartment (1) integrates a transfer barrel (10) and a lifting component for lifting the transfer barrel (10). The outer side of the transfer barrel (10) integrates a sealing plate (11) and an elastic component for maintaining the sealing plate (11). The inner wall of the vertical compartment (1) is fixedly connected to a protruding edge (9).

2. The behavioral detection device for animals with cerebral ischemia according to claim 1, characterized in that, The outer wall of the dark box (6) is fixedly connected to a sliding sleeve (7), and the top of the sliding sleeve (7) is integrated with a fixing part for fixing the sliding sleeve (7) to the balance beam (3).

3. The behavioral detection device for animals with cerebral ischemia according to claim 2, characterized in that, The fixing part includes a positioning rod (8) that is screwed into the top of the sliding sleeve (7), and the open end of the positioning rod (8) abuts against the top of the balance beam (3).

4. The behavioral detection device for animals with cerebral ischemia according to claim 3, characterized in that, The lifting assembly includes a drive component that is fixedly connected to the inner wall of the vertical compartment (1), and a transmission rod (12) is fixedly connected to the output end of the drive component. A screw sleeve that is fixedly connected to the outer wall of the transmission rod (12) is screwed onto the outer wall of the transmission rod (12).

5. The behavioral detection device for animals with cerebral ischemia according to claim 4, characterized in that, The inner wall of the vertical compartment (1) is fixedly connected to an L-shaped partition, and the horizontal end of the screw sleeve is slidably connected to the inner wall of the composite plate through a vertically set sliding groove.

6. The behavioral detection device for animals with cerebral ischemia according to claim 5, characterized in that, The elastic component includes a smooth rod (14) and a connecting sleeve (13) that are fixedly connected to the transfer barrel (10) and the sealing plate (11) respectively. The inner wall of the connecting sleeve (13) is slidably connected to the outer wall of the smooth rod (14), and a spring (15) is fixedly connected between the bottom of the connecting sleeve (13) and the inner wall of the transfer barrel (10).

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