A patch type multi-physiological parameter monitor

Abstract

The application discloses a patch type multi-physiological parameter monitor, which comprises a host computer, a dual-mode sensor for monitoring human skin temperature, breathing frequency and heart rate signals, and a sweat monitoring sensor for monitoring sweat flow and concentration of human sweat signals; the dual-mode sensor and the sweat monitoring sensor are connected with the host computer; the sweat monitoring sensor comprises a flexible patch body, a micro-fluid channel and an electrode integrated on the micro-fluid channel are arranged on the flexible patch body; the electrode comprises a spiral electrode and an ion selective electrode. The utility model can satisfy real-time monitoring of multi-physiological parameters of human body.

Description

Technical Field

[0001] This application relates to a patch-type multi-parameter physiological monitor, belonging to the technical field of physiological monitoring equipment. Background Technology

[0002] A multi-parameter monitor is a medical device that integrates multiple physiological parameter monitoring functions. It can collect key vital sign data of patients in real time, continuously, non-invasively, or minimally invasively, providing important data for clinical diagnosis, treatment, and intensive care. Currently, in clinical use, medical multi-parameter monitors generally monitor basic physiological parameters such as electrocardiogram, respiration, blood pressure, body temperature, and pulse rate, but this coverage is insufficient for the needs of home health monitoring. Because vital sign parameters such as sweat parameters are not fully monitored, it cannot meet the individual's needs for daily health care. Utility Model Content

[0003] According to one aspect of this application, a patch-type multi-physiological parameter monitor is provided, which can meet the real-time monitoring of multiple physiological parameters of the human body.

[0004] A patch-type multi-physiological parameter monitor, characterized in that it comprises:

[0005] Host;

[0006] Dual-mode sensor for monitoring human skin temperature, respiratory rate and heart rate signals;

[0007] Sweat monitoring sensor, used to monitor sweat signals, including the flow and concentration of sweat in the human body;

[0008] The dual-mode sensor and the sweat monitoring sensor are connected to the host computer.

[0009] The sweat monitoring sensor includes a flexible patch, on which microfluidic channels are provided and electrodes are integrated on the microfluidic channels;

[0010] The electrodes include helical electrodes and ion-selective electrodes.

[0011] Furthermore, the dual-mode sensor includes a temperature-sensitive layer and a force-sensitive layer stacked together;

[0012] The temperature-sensitive layer includes a first PET film and a temperature-sensitive material layer adhered to the first PET film;

[0013] The force-sensitive layer includes a second PET film and a pressure-sensitive material layer adhered to the second PET film.

[0014] Furthermore, the host computer is coupled with a data acquisition unit, a comparison unit, and a control unit;

[0015] The acquisition unit is used to acquire physiological parameter data detected by the dual-mode sensor and the sweat monitoring sensor, and send the physiological parameter data to the comparison unit;

[0016] The comparison unit is used to compare the physiological parameters with a set threshold, obtain the comparison result, and transmit the comparison result to the control unit;

[0017] The control unit is used to receive the comparison results and generate electrical signals to determine abnormalities in human physiological parameters.

[0018] The beneficial effects that this application can produce include:

[0019] The patch-type multi-physiological parameter monitor provided in this application achieves real-time monitoring of six parameters (body temperature, heart rate, respiratory rate, sweat flow, Na+, and Sodium) by setting up a dual-mode sensor and a sweat monitoring sensor. + / K + (Concentration), covering the needs of family health monitoring and meeting the needs of individuals for daily health care. At the same time, the microfluidic structure and electrodes work together to achieve simultaneous flow-composition monitoring; the introduction of ion-selective electrodes expands the dimensions of traditional sweat monitoring and provides more biomarker information for clinical use. Attached Figure Description

[0020] Figure 1 This is a schematic diagram of the structure of a patch-type multi-physiological parameter monitor according to one embodiment of this application.

[0021] Figure 2 This is a structural principle block diagram of a patch-type multi-physiological parameter monitor according to one embodiment of this application;

[0022] Component and drawing reference list: 1-Main unit; 2-Dual-mode sensor; 3-Sweat monitoring sensor; 4-Microfluidic cavity; 5-Helical electrode; 6-Ion-selective electrode; 7-Thermosensitive layer; 8-Force-sensitive layer; 9-Acquisition unit; 10-Comparison unit; 11-Control unit. Detailed Implementation

[0023] The present application is described in detail below with reference to the embodiments, but the present application is not limited to these embodiments.

[0024] See Figure 1-2 A patch-type multi-physiological parameter monitor, characterized in that it comprises:

[0025] Host 1;

[0026] Dual-mode sensor 2 is used to monitor human skin temperature, respiratory rate, and heart rate signals.

[0027] Sweat monitoring sensor 3 is used to monitor the sweat signal of human sweat flow and concentration;

[0028] The dual-mode sensor 2 and the sweat monitoring sensor 3 are connected to the host 1;

[0029] The sweat monitoring sensor 3 includes a flexible patch body, on which a microfluidic channel 4 and an electrode integrated on the microfluidic channel 4 are disposed, and the microfluidic channel is a PDMS microfluidic channel.

[0030] The electrodes include a helical electrode 5 and an ion-selective electrode 6.

[0031] Specifically, this patch-type multi-physiological parameter monitor mainly consists of a main unit 1, a dual-mode sensor 2, and a sweat monitoring sensor 3. These three components work together through interconnection to simultaneously monitor multiple human physiological parameters. It features integration and portability, making it suitable for long-term continuous monitoring scenarios such as sports health monitoring and clinical auxiliary diagnosis. The dual-mode sensor 2 is responsible for acquiring multi-modal physiological signals. It senses changes in skin surface temperature through a thermistor or infrared sensor, reflecting basal metabolism, fever status, or environmental adaptability. It may indirectly reflect respiratory system function based on chest and abdominal motion sensing (such as strain gauges) or changes in respiratory airflow impedance (such as impedance sensors). It employs photoplethysmography (PPG) to capture changes in blood volume through a reflective / transmissive photoelectric sensor to calculate heart rate. The integrated multi-parameter monitoring of the sensors reduces device size and power consumption, making it suitable for wearable device scenarios. The sweat monitoring sensor 3 consists of a PDMS microfluidic cavity and an electrode system, enabling sweat flow and composition analysis. The PDMS microfluidic cavity serves as a sweat collection and transport channel, utilizing the biocompatibility and flexibility of polydimethylsiloxane (PDMS) to conform to the skin and guide the directional flow of sweat. The micron-level channel size optimizes fluid resistance, preventing sweat residue, while the hydrophobic surface treatment reduces non-specific adsorption and improves detection accuracy. The spiral electrode 5, a spiral metal electrode (such as gold / platinum), increases the surface area and enhances the sensitivity of the electrochemical signal. It monitors sweat conductivity, indirectly reflecting sweat flow (conductivity is positively correlated with flow rate). The ion-selective electrode 6 is based on an ion-selective membrane (such as a PVC membrane) for specific ions (such as Na+). + / K + The selective response of the sensor allows for the calculation of ion concentration via potential difference. It is used for diagnosing electrolyte imbalances (such as hyponatremia) and assessing metabolic status (such as ketone body levels). The dual-mode sensor, sweat monitoring sensor, and main unit are integrated on a flexible substrate to achieve patch-based physiological monitoring.

[0032] This application enables real-time monitoring of six parameters (body temperature, heart rate, respiratory rate, sweat flow, Na+, etc.). + / K +(Concentration), covering the needs of family health monitoring and meeting the needs of individuals for daily health care. At the same time, the microfluidic structure and electrodes work together to achieve simultaneous flow-component monitoring; the introduction of ion-selective electrode 6 expands the dimensions of traditional sweat monitoring and provides more biomarker information for clinical use.

[0033] The dual-mode sensor 2 includes a temperature-sensitive layer 7 and a force-sensitive layer 8 stacked together.

[0034] The temperature-sensitive layer 7 includes a first PET film and a temperature-sensitive material layer adhered to the first PET film;

[0035] The force-sensitive layer 8 includes a second PET film and a pressure-sensitive material layer adhered to the second PET film.

[0036] Specifically, the PET film, as a flexible substrate, provides mechanical support and electrical insulation, ensuring the sensor adheres to the skin and is tear-resistant. For temperature-sensitive materials, NTC thermistors (negative temperature coefficient) are suitable for wide-temperature monitoring, while infrared sensitive layers (such as vanadium oxide) enable non-contact temperature measurement. For pressure-sensitive materials, piezoelectric ceramics are suitable for high-frequency vibration monitoring, and resistive strain gauges (such as metal foil) are low-cost and highly linear. The temperature-sensitive layer 7 and the force-sensitive layer 8 are physically separated by the PET film to avoid cross-interference (such as temperature changes affecting the resistance of the pressure-sensitive material). For respiratory monitoring, the force-sensitive layer 8 detects periodic fluctuations in the chest and abdomen (pressure change frequency corresponds to respiratory rate). The temperature-sensitive layer 7 monitors perinasal / perioral temperature fluctuations (exhaled gas temperature changes assist in verification). For heart rate monitoring, the force-sensitive layer 8 captures micro-deformations of the skin caused by arterial pulsation. The temperature-sensitive layer 7 monitors temperature changes caused by blood perfusion in peripheral areas such as fingertips / earlobes (simultaneously verifying heart rate).

[0037] It is worth noting that the working principle of the sweat monitoring sensor is that after sweat flows in along multiple channels, the amount of sweat is determined by the channel volume and the impedance value between the bimetallic electrodes; the working principle of the dual-mode sensor is that temperature changes cause changes in the value of the thermosensitive resistor, and the force-sensitive sensing layer combined with the nano-conductive material works synergistically to sense very small pressure changes, thereby outputting an electrical signal.

[0038] The host 1 is internally coupled with a data acquisition unit 9, a comparison unit 10, and a control unit 11;

[0039] The specific models of the comparison unit include MAX30100, MAX86906, GH3220, ADPD6000, etc., and the specific models of the control unit include STM32F446VET6, nRF52832, ESP32, TI CC2650, etc.

[0040] The acquisition unit 9 is used to acquire physiological parameter data detected by the dual-mode sensor 2 and the sweat monitoring sensor 3, and send the physiological parameter data to the comparison unit 10;

[0041] The comparison unit 10 is used to compare the physiological parameters with a set threshold, obtain the comparison result, and transmit the comparison result to the control unit 11;

[0042] The control unit 11 is used to receive the comparison result and generate an electrical signal. The control unit 11 can be connected to a display device or a detection backend to transmit relevant signals to the display device or detection backend, so that users or medical personnel can make basic reference judgments on abnormal human physiological parameters.

[0043] Specifically, the acquisition unit 9 can use a multiplexer (MUX) to switch the signal channels of the dual-mode sensor 2 and the sweat monitoring sensor 3, sharing ADC resources to reduce power consumption. For the weak electrochemical signals (such as μA-level current) of the sweat monitoring sensor 3, an integrated transimpedance amplifier (TIA) is used to improve the signal-to-noise ratio. The comparison unit 10 can directly determine whether a single parameter exceeds the threshold range based on clinical guidelines (such as triggering an alarm when body temperature > 38.5℃). It can also reflect changes in multiple parameters, such as low body temperature + low sweat sodium ion concentration, allowing users to make a basic judgment on abnormal physical conditions based on the feedback parameters.

[0044] The above description is merely a few embodiments of this application and is not intended to limit this application in any way. Although this application discloses preferred embodiments as described above, it is not intended to limit this application. Any changes or modifications made by those skilled in the art without departing from the scope of the technical solution of this application using the disclosed technical content are equivalent to equivalent implementation cases and fall within the scope of the technical solution.

Claims

1. A patch-type multi-physiological parameter monitor, characterized in that, include: Host (1); Dual-mode sensor (2) is used to monitor human skin temperature, respiratory rate and heart rate signals; A sweat monitoring sensor (3) is used to monitor the sweat signal of human sweat flow and concentration; The dual-mode sensor (2) and the sweat monitoring sensor (3) are connected to the host (1); The sweat monitoring sensor (3) includes a flexible patch body, on which a microfluidic channel (4) is provided and an electrode is integrated on the microfluidic channel (4); The electrodes include a helical electrode (5) and an ion-selective electrode (6).

2. The patch-type multi-physiological parameter monitor according to claim 1, characterized in that, The dual-mode sensor (2) includes a temperature-sensitive layer (7) and a force-sensitive layer (8) stacked together. The temperature-sensitive layer (7) includes a first PET film and a temperature-sensitive material layer adhered to the first PET film; The force-sensitive layer (8) includes a second PET film and a pressure-sensitive material layer adhered to the second PET film.

3. The patch-type multi-physiological parameter monitor according to claim 1, characterized in that, The host (1) is internally coupled with a data acquisition unit (9), a comparison unit (10), and a control unit (11). The acquisition unit (9) is used to acquire physiological parameter data detected by the dual-mode sensor (2) and the sweat monitoring sensor (3), and send the physiological parameter data to the comparison unit (10). The comparison unit (10) is used to compare the physiological parameters with a set threshold, obtain the comparison result, and transmit the comparison result to the control unit (11). The control unit (11) is used to receive the comparison result and generate an electrical signal to realize the judgment of abnormal human physiological parameters.

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