A disposable leukocyte-removal plastic blood bag drip bottle structure

Abstract

The utility model discloses a disposable leukocyte removal plastic blood bag is with drip bottle structure, including sampling subassembly, main pipeline, filter section and collection subassembly, sampling subassembly, filter section and collection subassembly pass along the blood flow direction main pipeline in proper order series connection, filter section sets up in sampling subassembly with collection subassembly middle, filter section includes drip bottle and filter, spiral exhaust device includes main cylinder, air inlet pipe, flow divider, air outlet pipe, blood vessel, spiral diversion groove, diversion hole and sealing plug, flow divider sets up in air inlet pipe, air outlet pipe is through setting in main cylinder inside, the outside of main cylinder is surrounded with spiral diversion groove has set up, main cylinder surface distribution has diversion hole, set up in diversion hole has sealing plug, and this device has solved the problem of low filtering efficiency and the lack of automatic exhaust function in the current drip bottle structure.

Description

Technical Field

[0001] This utility model belongs to the field of blood bag technology, specifically relating to a drip chamber structure for a disposable leukocyte-reducing plastic blood bag. Background Technology

[0002] In the field of transfusion medicine, removing leukocytes from blood products is a crucial step in preventing transfusion reactions and reducing the risk of viral transmission. Traditional leukocyte-reduced blood bags typically employ an internal filter structure, using physical filtration to retain leukocytes. However, existing technologies suffer from the following significant drawbacks: Current drip chambers are designed with an arc-shaped upper end and a straight, sealed lower end on a single plane. During vacuum packaging, the drip chamber is easily compressed by other blood bag components, causing deformation and flattening of the internal space, affecting the blood drip rate and reducing filtration efficiency. Prolonged filtration time negatively impacts blood quality and increases the risk of hemolysis. Furthermore, because the drip chamber lacks an venting function, gas enters the filtered blood bag along with the filtered blood, requiring manual venting to remove the gas. This process can push some blood into a bypass, resulting in waste, and the compression of the blood bag can also damage a small number of red blood cells. This venting process is time-consuming and labor-intensive, reducing preparation efficiency. There is an urgent need for a drip chamber design that addresses the problems of low filtration efficiency and the lack of automatic venting in existing technologies. Utility Model Content

[0003] The purpose of this invention is to provide a disposable drip chamber structure for leukocyte-reducing plastic blood bags, in order to solve the problems mentioned in the background art.

[0004] To solve the above-mentioned technical problems, this utility model provides the following technical solution: a disposable leukocyte-reducing plastic blood bag drip chamber structure, including a sampling component, a main pipe, a filtering section, and a collection component. The sampling component, the filtering section, and the collection component are connected in series along the blood flow direction through the main pipe. The filtering section is located between the sampling component and the collection component. The filtering section includes a drip chamber and a filter. The outlet of the drip chamber is connected to the inlet of the filter through the main pipe. The drip chamber has a cross-shaped staggered upper and lower sealing structure. An installation port is opened on the side of the drip chamber. The drip chamber includes a spiral exhaust device, a hydrophobic air filter, and a filter screen. The filter screen is fixedly installed in the main pipe inside the drip chamber body. The hydrophobic air filter is tightly connected to the installation port on the drip chamber body through a rubber ring.

[0005] The inlet of the spiral exhaust device is connected to the main pipe, and the outlet of the spiral exhaust device is connected to the filter. The spiral exhaust device includes a main cylinder, an inlet pipe, a distributor, an outlet pipe, an outlet tube, a spiral guide groove, a guide hole, and a sealing plug. The distributor is disposed in the inlet pipe, and the outlet pipe is disposed through the interior of the main cylinder. The spiral guide groove is arranged around the outer side of the main cylinder. The guide holes are distributed on the surface of the main cylinder, and the sealing plug is disposed in the guide holes. The first end of the spiral guide groove is connected to the inlet pipe, the tail end of the spiral guide groove is connected to the outlet tube, and the other end of the outlet tube is connected to the main pipe.

[0006] The present invention further describes that the sampling component includes a sample retention needle, a sample retention bag, a sampling needle, and a collection bag. The sample retention needle is fixed to the top of the sample retention bag in a vertical orientation, and the tip of the sample retention needle is exposed. The tail end of the sampling needle is connected to the sample retention bag and the collection bag respectively. The collection bag is connected to the inlet of the filtration section through the main pipe.

[0007] The present invention further describes that the collection component includes a collection bag, a red blood cell preservation bag, and a plasma bag. The filtration section is synchronously connected to the collection bag, the red blood cell preservation bag, and the plasma bag through the branched main pipe. The collection bag is independently connected to the red blood cell preservation bag and the plasma bag through the branched main pipe.

[0008] The present invention further describes that the main pipe is made of transparent medical-grade PVC material with an inner diameter of 3.2±0.2mm and a wall thickness of 0.5-0.7mm. The hydrophobic air filter is a PTFE microporous membrane structure with a porosity ≥85% and a pore size distribution of 0.2-0.45μm.

[0009] The present invention further explains that the medium filling density of the filter is 0.35-0.45 g / cm³, and the porosity is 92-95%.

[0010] This utility model further illustrates that the main cylinder of the spiral exhaust device is made of polycarbonate and silicone through co-injection molding.

[0011] This utility model further explains that the filter screen is a three-layer filter, with the upper layer being a nylon coarse filter screen with a pore size of 100-120μm, the middle layer being a stainless steel precision filter screen with a pore size of 40-60μm, and the lower layer being a polymer filter membrane with a pore size of 20-30μm.

[0012] The present invention further explains that the pitch of the spiral guide groove is 5-8mm, the groove depth is 1.2-1.8mm, and its inner surface is treated with a nano-hydrophobic coating.

[0013] Compared with existing technologies, the beneficial effects achieved by this utility model are as follows: This utility model, by setting a spiral exhaust device and a hydrophobic air filter, can realize the automatic exhaust function of blood bags, prevent air bubbles from entering the filtered blood, reduce the tediousness of manual operation and the resulting blood waste and red blood cell damage; by designing the overall shape of the drip chamber as a cross-shaped staggered upper and lower sealing structure, the pressure resistance of the drip chamber is greatly enhanced, effectively avoiding the problem of the internal space of the drip chamber being squeezed and deformed during the vacuum packaging of blood bags, thus improving the preparation efficiency; the progressive pitch design of the spiral guide groove (5-8mm) combined with the nano-hydrophobic coating, through the centrifugal force stratification principle, allows the gas to be quickly thrown towards the main cylinder during spiral motion, improving the gas separation efficiency by more than 60% compared with traditional vertical drip chambers; the elastic silicone sealing plug embedded in the guide hole opens unidirectionally under a pressure of 0.5-1.2kPa, realizing the directional discharge of gas and zero liquid leakage, and clinical tests show that the plasma loss rate is <0.3%. Attached Figure Description

[0014] The accompanying drawings are provided to further illustrate the present invention and form part of the specification. They are used together with the embodiments of the present invention to explain the present invention, but do not constitute a limitation thereof. In the drawings:

[0015] Figure 1 This is a schematic diagram of the overall structure of this utility model;

[0016] Figure 2 This is a front view schematic diagram of the drip pot of this utility model;

[0017] Figure 3 This is a front view schematic diagram of the spiral exhaust device of this utility model;

[0018] Figure 4 This is a three-dimensional schematic diagram of the spiral exhaust device of this utility model;

[0019] In the diagram: 1. Sampling assembly; 2. Main pipe; 3. Filter section; 4. Collection assembly; 5. Dropper; 6. Filter; 7. Spiral exhaust device; 8. Hydrophobic air filter; 9. Filter screen; 10. Installation port; 1-1. Sample needle; 1-2. Sample bag; 1-3. Sampling needle; 1-4. Collection bag; 4-1. Collection bag; 4-2. Red blood cell preservation bag; 4-3. Plasma bag; 7-1. Main cylinder; 7-2. Air inlet pipe; 7-3. Diverter; 7-4. Air outlet pipe; 7-5. Outlet blood vessel; 7-6. Spiral guide groove; 7-7. Guide hole; 7-8. Sealing plug. Detailed Implementation

[0020] The following detailed, non-limiting description of the present invention, in conjunction with preferred embodiments and accompanying drawings, is provided. Obviously, the described embodiments are merely some, not all, of the embodiments of the present invention. All other embodiments obtained by those skilled in the art based on the embodiments of the present invention without inventive effort are within the scope of protection of the present invention.

[0021] Please see Figure 1-4 This utility model provides a technical solution: a disposable leukocyte-reducing plastic blood bag drip chamber structure, including a sampling component 1, a main pipe 2, a filter section 3, and a collection component 4. The sampling component 1, the filter section 3, and the collection component 4 are connected in series along the blood flow direction through the main pipe 2. The filter section 3 is located between the sampling component 1 and the collection component 4. The filter section 3 includes a drip chamber 5 and a filter 6. The outlet of the drip chamber 5 is connected to the inlet of the filter 6 through the main pipe 2. The drip chamber 5 has a cross-shaped staggered upper and lower sealing structure. An installation port 10 is opened on the side of the drip chamber 5. The drip chamber 5 includes a spiral exhaust device 7, a hydrophobic air filter 8, and a filter screen 9. The filter screen 9 is fixedly installed in the main pipe 2 inside the main body of the drip chamber 5. The hydrophobic air filter 8 is tightly connected to the installation port 10 on the main body of the drip chamber 5 through a rubber ring.

[0022] The inlet of the spiral exhaust device 7 is connected to the main pipe 2, and the outlet of the spiral exhaust device 7 is connected to the filter 6. The spiral exhaust device 7 includes a main cylinder 7-1, an inlet pipe 7-2, a distributor 7-3, an outlet pipe 7-4, an outlet tube 7-5, a spiral guide groove 7-6, a guide hole 7-7, and a sealing plug 7-8. The distributor 7-3 is installed in the inlet pipe 7-2, and the outlet pipe 7-4 is installed inside the main cylinder 7-1. The spiral guide groove 7-6 is arranged around the outside of the main cylinder 7-1. The guide holes 7-7 are distributed on the surface of the main cylinder 7-1, and the sealing plug 7-8 is installed in the guide holes 7-7. The first end of the spiral guide groove 7-6 is connected to the inlet pipe 7-2, and the tail end of the spiral guide groove 7-6 is connected to the outlet tube 7-5. The other end of the outlet tube 7-5 is connected to the main pipe 2.

[0023] The sampling assembly 1 includes a sample retention needle 1-1, a sample retention bag 1-2, a sampling needle 1-3, and a collection bag 1-4. The sample retention needle 1-1 is fixed to the top of the sample retention bag 1-2 in a vertical orientation, with the tip of the sample retention needle 1-1 exposed. The tail end of the sampling needle 1-3 is connected to the sample retention bag 1-2 and the collection bag 1-4 respectively. The collection bag 1-4 is connected to the inlet of the filter section 3 through the main pipe 2.

[0024] The collection component 4 includes a collection bag 4-1, a red blood cell preservation bag 4-2, and a plasma bag 4-3. The filtration section 3 is synchronously connected to the collection bag 4-1, the red blood cell preservation bag 4-2, and the plasma bag 4-3 through a branched main pipe 2. The collection bag 4-1 is independently connected to the red blood cell preservation bag 4-2 and the plasma bag 4-3 through a branched main pipe 2.

[0025] The main pipe 2 is made of transparent medical-grade PVC material with an inner diameter of 3.2±0.2mm and a wall thickness of 0.5-0.7mm. The hydrophobic air filter 8 is a PTFE microporous membrane structure with a porosity ≥85% and a pore size distribution of 0.2-0.45μm. Referring to standards such as GB / T10002.3-2003, the wall thickness range is determined by simulating the deformation and rupture threshold of the pipe under fluid pressure. At the same time, the thermal cycling test (such as GB / T8814-2004) verifies the material's expansion coefficient under temperature changes to ensure that the inner diameter tolerance meets the usage requirements. According to air filtration standards (such as EN1822), the influence of pore size distribution on filtration efficiency is verified through aerosol interception experiments to ensure that the 0.2-0.45μm pore size can effectively block bacteria or particles.

[0026] The filter 6 has a media filling density of 0.35-0.45 g / cm³ and a porosity of 92-95%. The main cylinder 7-1 of the spiral exhaust device 7 is made of polycarbonate and silicone through co-injection molding. The filter screen 9 is a three-layer filter: the upper layer is a nylon coarse filter screen with a pore size of 100-120 μm, the middle layer is a stainless steel precision filter screen with a pore size of 40-60 μm, and the lower layer is a polymer filter membrane with a pore size of 20-30 μm. The spiral guide groove 7-6 has a pitch of 5-8 mm and a groove depth of 1.2-1.8 mm. Its inner surface is treated with a nano-hydrophobic coating.

[0027] The progressive pitch design (5-8mm) of the spiral guide channel 7-6, combined with a nano-hydrophobic coating, uses the centrifugal force stratification principle to rapidly throw the gas into the main cylinder 7-1 during spiral motion. The gas separation efficiency is more than 60% higher than that of traditional vertical drippers. The elastic silicone sealing plug 7-8 embedded in the guide hole 7-7 opens unidirectionally under a pressure of 0.5-1.2kPa, achieving directional gas discharge with zero liquid leakage. Clinical tests show that the plasma loss rate is <0.3%. The spiral flow channel forces the blood to form a laminar flow along the tangential direction, avoiding the red blood cell collision damage caused by turbulence (Re>2000) in traditional straight-through drippers.

[0028] The filtration section mainly consists of a drip pot, a filter screen, and a hydrophobic air filter. The drip pot body is made of one-piece molded plastic with a cross-shaped staggered top and bottom sealing structure. The filter screen is fixed inside the drip pot body to ensure that the blood can be fully filtered. The hydrophobic air filter is tightly connected to the pre-drilled mounting port on the drip pot body via a sealing ring to ensure a tight seal.

[0029] Hydrophobic air filter: Functionally, it primarily enables automatic venting, preventing air bubbles from entering the filtered blood and avoiding blood waste and red blood cell damage caused by manual venting. Its structural feature is the use of hydrophobic filter material with fine internal pores, effectively separating gas and liquid. The filter's shape is designed to match the mounting port of the drip chamber, ensuring effective operation through a sealed connection.

[0030] Working Principle: When using a leukocyte-reduced blood bag for filtration, whole blood, after passing through the sampling component, flows into the drip chamber from the bag's inlet. Due to the drip chamber's unique cross-shaped staggered upper and lower sealing structure, even when squeezed by other components during the vacuum packaging process of the blood bag, the internal space of the drip chamber remains relatively stable and will not be easily crushed, thus ensuring that the blood flows into the drip chamber at a stable flow rate. As the blood flows within the drip chamber, it passes through a filter screen, which intercepts tiny clots in the blood, performing preliminary filtration and reducing the possibility of tiny clots entering subsequent blood bags, thus improving blood quality. During the filtration process, the blood passes through a spiral exhaust device, and the filtered blood... Blood enters the main cylinder through the air inlet pipe and then the splitter. The split blood collides with the spiral guide groove on the main cylinder, resulting in blood-gas separation. The blood flows along the spiral guide groove and enters the main pipe after reaching the end of the spiral guide groove. Excess gas remains in the main cylinder and is discharged through the air outlet pipe and guide hole. At the same time, the gas in the drip chamber and pipeline is discharged from the drip chamber through the hydrophobic air filter. The hydrophobic air filter only allows gas to pass through and prevents blood from passing through, thus preventing gas from entering the filtered blood bag with the blood and eliminating the need for manual air venting. After passing through the filtration section, the blood is split into the collection bag, red blood cell preservation bag, and plasma bag to complete the process of removing white blood cells from the blood.

[0031] In the description of this utility model, it should be understood that the terms "upper", "lower", "front", "rear", "left", "right", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings, and are only for the convenience of describing this utility model, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model.

[0032] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of this utility model, and are not intended to limit it. Although this utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some of the technical features. Such modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the spirit and scope of the technical solutions of the embodiments of this utility model.

Claims

1. A disposable leukocyte-reduced plastic blood bag drip chamber structure, comprising a sampling component (1), a main pipe (2), a filter section (3), and a collection component (4), characterized in that: The sampling component (1), the filtration section (3) and the collection component (4) are connected in series along the blood flow direction through the main pipe (2). The filtration section (3) is located between the sampling component (1) and the collection component (4). The filtration section (3) includes a drip pot (5) and a filter (6). The outlet of the drip pot (5) is connected to the inlet of the filter (6) through the main pipe (2). The drip pot (5) has a cross-shaped upper and lower sealed structure. The drip pot (5) has an installation port (10) on its side. The drip pot (5) includes a spiral exhaust device (7), a hydrophobic air filter (8) and a filter screen (9). The filter screen (9) is fixedly installed in the main pipe (2) inside the body of the drip pot (5). The hydrophobic air filter (8) is tightly connected to the installation port (10) on the body of the drip pot (5) through a rubber ring. The inlet of the spiral exhaust device (7) is connected to the main pipe (2), and the outlet of the spiral exhaust device (7) is connected to the filter (6). The spiral exhaust device (7) includes a main cylinder (7-1), an inlet pipe (7-2), a distributor (7-3), an outlet pipe (7-4), an outlet tube (7-5), a spiral guide groove (7-6), a guide hole (7-7), and a sealing plug (7-8). The distributor (7-3) is installed in the inlet pipe (7-2), and the outlet pipe (7-4) is installed through the filter (6). Inside the main cylinder (7-1), a spiral guide groove (7-6) is arranged around the outer side of the main cylinder (7-1). Guide holes (7-7) are distributed on the surface of the main cylinder (7-1). A sealing plug (7-8) is arranged in the guide hole (7-7). The first end of the spiral guide groove (7-6) is connected to the air inlet pipe (7-2). The tail end of the spiral guide groove (7-6) is connected to the outlet blood vessel (7-5). The other end of the outlet blood vessel (7-5) is connected to the main pipe (2).

2. The structure of a disposable leukocyte-reducing plastic blood bag drip chamber according to claim 1, characterized in that: The sampling component (1) includes a sample retention needle (1-1), a sample retention bag (1-2), a sampling needle (1-3), and a collection bag (1-4). The sample retention needle (1-1) is fixed to the top of the sample retention bag (1-2) in a vertical orientation. The tip of the sample retention needle (1-1) is exposed. The tail end of the sampling needle (1-3) is connected to the sample retention bag (1-2) and the collection bag (1-4) respectively. The collection bag (1-4) is connected to the inlet of the filter section (3) through the main pipe (2).

3. The structure of a disposable leukocyte-reducing plastic blood bag drip chamber according to claim 1, characterized in that: The collection component (4) includes a collection bag (4-1), a red blood cell preservation bag (4-2), and a plasma bag (4-3). The filtration section (3) is synchronously connected to the collection bag (4-1), the red blood cell preservation bag (4-2), and the plasma bag (4-3) through a branch of the main pipe (2). The collection bag (4-1) is independently connected to the red blood cell preservation bag (4-2) and the plasma bag (4-3) through a branch of the main pipe (2).

4. The structure of a disposable leukocyte-reducing plastic blood bag drip chamber according to claim 1, characterized in that: The main pipe (2) is made of transparent medical grade PVC material with an inner diameter of 3.2±0.2mm and a wall thickness of 0.5-0.7mm. The hydrophobic air filter (8) is a PTFE microporous membrane structure with a porosity ≥85% and a pore size distribution of 0.2-0.45μm.

5. The structure of a disposable leukocyte-reducing plastic blood bag drip chamber according to claim 1, characterized in that: The filter (6) has a media packing density of 0.35-0.45 g / cm³ and a porosity of 92-95%.

6. The structure of a disposable leukocyte-reducing plastic blood bag drip chamber according to claim 1, characterized in that: The filter (9) is a three-layer filter, with the upper layer being a nylon coarse filter with a pore size of 100-120μm, the middle layer being a stainless steel precision filter with a pore size of 40-60μm, and the lower layer being a polymer filter membrane with a pore size of 20-30μm.

7. The structure of a disposable leukocyte-reducing plastic blood bag drip chamber according to claim 1, characterized in that: The spiral guide groove (7-6) has a pitch of 5-8 mm and a groove depth of 1.2-1.8 mm, and its inner surface is treated with a nano-hydrophobic coating.

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