Platelet separation and extraction instrument for preparing PRP

Abstract

The utility model discloses a kind of platelet separation and extraction instruments for preparing PRP, comprising: fixed seat;Swing shaft, is rotatably supported on fixed seat by bearing, swing shaft's axis extends along front-back direction;Swing frame, upper end fixedly connected swing shaft;Carry pipe frame, detachably set on swing frame, carry pipe frame is configured as loading collection tube;Drive unit;Transmission mechanism, including hingedly in turn crank, connecting rod and rocker, the end of crank away from connecting rod is fixedly connected with output shaft, the end of rocker away from connecting rod is fixedly connected with swing shaft;When drive unit drives output shaft to rotate unidirectionally around its own axis, output shaft drives swing frame to reciprocate in the preset angle range with swing shaft as rotation center by transmission mechanism.The separation and extraction instrument can ensure that the extraction rate of platelet is higher and stable, rocker and collection tube run continuously smoothly, without pause, shorten the overall shaking operation time, effectively improve the extraction efficiency of platelet.

Description

Technical Field

[0001] This utility model relates to the field of platelet-rich plasma preparation technology, and in particular to a platelet separation and extraction instrument for preparing platelet-rich plasma. Background Technology

[0002] In preparing platelet-rich plasma (PRP), blood samples are first collected into collection tubes pre-filled with separating gel. After centrifugation, the blood sample and separating gel in the collection tube separate into layers from top to bottom: plasma layer, platelet layer, separating gel layer, and erythrocyte layer. Most of the plasma in the plasma layer is first extracted using a syringe to obtain platelet-poor plasma (PPP). A small amount of plasma remains in the collection tube. Then, the collection tube is tapped or shaken manually or automatically to detach most of the platelets from the separating gel layer and mix them thoroughly with the remaining plasma to form PRP. The separating gel layer isolates the PRP from the erythrocyte layer during this process. Finally, another syringe is used to extract the PRP from the collection tube, achieving the goal of separating and extracting platelets from the separating gel layer. The small amount of platelets that fail to detach from the separating gel layer and remain on it cannot be extracted and utilized.

[0003] Manually tapping the collection tube is inefficient. Different operators have varying levels of skill in tapping, sometimes resulting in more platelets remaining on the separation gel layer, affecting the platelet extraction rate and causing inconsistent PRP quality. Existing automated instruments often use a motor to directly drive a swing shaft to shake the collection tube. Specifically, the motor drives the swing shaft to swing back and forth alternately in forward and reverse directions, causing the collection tube to swing back and forth within a certain angle range. When the motor switches between forward and reverse directions, the speed first drops to zero and then accelerates in the opposite direction, resulting in obvious pauses and poor operational stability. This also prolongs the overall shaking time, leading to insufficient extraction efficiency. Utility Model Content

[0004] This invention aims to solve at least one of the technical problems existing in the prior art. To this end, this invention proposes a platelet separation and extraction instrument for preparing PRP, which can improve the extraction rate and efficiency of platelets.

[0005] A platelet separation and extraction instrument for preparing PRP according to an embodiment of the present invention includes: a fixed base; a swing shaft rotatably supported on the fixed base by bearings, the axis of the swing shaft extending in a front-rear direction; a swing frame, the upper end of which is fixedly connected to the swing shaft; a tube holder detachably mounted on the swing frame, the tube holder being configured to load collection tubes, and the length direction of the collection tubes being perpendicular to the axis of the swing shaft; a drive unit mounted on the fixed base, the drive unit including an output shaft whose axis extends in a front-rear direction, the drive unit being configured to drive the output shaft to rotate around its own axis; and a transmission mechanism including a crank, a connecting rod, and a rocker arm hinged in sequence, the end of the crank away from the connecting rod being fixedly connected to the output shaft, and the end of the rocker arm away from the connecting rod being fixedly connected to the swing shaft; when the drive unit drives the output shaft to rotate unidirectionally around its own axis, the output shaft drives the swing frame to reciprocate within a preset angle range around the swing shaft as the rotation center through the transmission mechanism.

[0006] The device offers at least the following advantages: The tube holder is detachably mounted on a swing frame. A swing shaft is fixedly mounted on the upper end of the swing frame, and the swing shaft is rotatably supported on a fixed base via bearings. The transmission mechanism includes a crank, a connecting rod, and a rocker arm, which are hinged sequentially. The end of the rocker arm away from the connecting rod is fixedly connected to the swing shaft, and the end of the crank arm away from the connecting rod is fixedly connected to the output shaft of the drive unit. The collection tube after PPP extraction is loaded onto the tube holder with its length direction perpendicular to the axis of the swing shaft. The drive unit is activated, and the output shaft rotates unidirectionally around its own axis, sequentially driving the swing shaft via the crank, connecting rod, and rocker arm. The frame oscillates back and forth within a preset angle range around the swing axis. During the oscillation, the plasma on the upper layer of the blood sample in the collection tube is affected by its own inertia. The plasma can wash away the platelets attached to the separating gel, causing most of the platelets to peel off from the separating gel layer. This ensures that the platelets and plasma are fully mixed, thus preparing PRP. This method ensures a high and stable platelet extraction rate. Moreover, the output shaft and crank only need to rotate in one direction at a constant speed, which allows the rocker and collection tube to run continuously and smoothly without interruption. This results in high energy efficiency, shortens the overall oscillation time, and effectively improves the platelet extraction efficiency.

[0007] According to some embodiments of the present invention, the swing shaft is rotatably supported on the fixed base by two bearings, the two bearings are arranged at intervals along the axis of the swing shaft, and the two bearings are respectively located in front of and behind the swing frame, or both bearings are located behind the swing frame.

[0008] According to some embodiments of the present invention, both bearings are located behind the swing frame, and the position on the swing shaft connecting the rocker arm is located between the two bearings.

[0009] According to some embodiments of the present invention, the fixed base includes a first support plate and a second support plate arranged at intervals along the front-back direction, and the swing shaft is rotatably supported on the first support plate and the second support plate by two bearings respectively.

[0010] According to some embodiments of this utility model, the length directions of the crank, the connecting rod, and the rocker arm are all perpendicular to the front-to-back direction.

[0011] According to some embodiments of the present invention, the tube carrier includes a connecting part and a loading groove. The connecting part is detachably connected to the swing frame. The extending direction of the loading groove is perpendicular to the axis of the swing shaft. The loading groove is used to position and load the collection tube.

[0012] According to some embodiments of the present invention, the carrier tube rack further includes a support portion and a radial constraint portion. The support portion is used to support the collection tube, and the radial constraint portion is used to press and constrain the side wall of the collection tube radially. The loading groove is formed by the support portion and the radial constraint portion.

[0013] According to some embodiments of the present invention, the radial constraint part has an observation window at a position corresponding to a portion of the side wall of the collection tube, and the observation window is connected to the loading groove.

[0014] According to some embodiments of the present invention, multiple tube racks are provided on both the left and right sides of the swing frame.

[0015] According to some embodiments of this utility model, the driving unit is a stepper motor, the driving unit drives the output shaft at a speed of 240~400 rpm, and the swing angle of the swing frame is less than or equal to 60°.

[0016] Additional aspects and advantages of this invention will be set forth in part in the description which follows, and in part will be obvious from the description, or may be learned by practice of the invention. Attached Figure Description

[0017] The present invention will be further described below with reference to the accompanying drawings and embodiments, wherein: Figure 1 This is a schematic diagram of the structure of an embodiment of the present utility model; Figure 2 This is a schematic diagram of the internal structure from one perspective of one embodiment of the present utility model; Figure 3 This is a schematic diagram of the internal structure from another perspective of an embodiment of the present utility model; Figure 4 This is a schematic diagram of the structure of the swing frame in one of the extreme positions in an embodiment of this utility model; Figure 5 This is a schematic diagram of the structure of the tube carrier in an embodiment of this utility model.

[0018] Reference numerals: 1. Fixed base; 11. First support plate; 12. Second support plate; 13. Foot pad; 2. Swing frame; 3. Swing shaft; 4. Loading tube rack; 41. Connecting part; 42. Loading groove; 43. Supporting part; 44. Radial constraint part; 45. Observation window; 5. Drive unit; 51. Output shaft; 6. Transmission mechanism; 61. Crank; 62. Connecting rod; 63. Rocker arm; 7. Bearing. Detailed Implementation

[0019] In the description of this utility model, it should be understood that the orientation descriptions, such as up, down, front, back, left, right, axis, radial, etc., indicating the orientation or positional relationship, are based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this utility model.

[0020] In the description of this utility model, the use of "first" and "second" is only for the purpose of distinguishing technical features and should not be construed as indicating or implying relative importance or implicitly indicating the number of technical features or the order of the technical features.

[0021] In the description of this utility model, unless otherwise explicitly defined, terms such as "setting," "installation," and "connection" should be interpreted broadly, and those skilled in the art can reasonably determine the specific meaning of the above terms in this utility model in conjunction with the specific content of the technical solution.

[0022] Reference Figures 1 to 4 This utility model discloses a platelet separation and extraction instrument for preparing PRP, including a fixed base 1, a swing frame 2, a swing shaft 3, a tube holder 4, a drive unit 5, a transmission mechanism 6, and a bearing 7.

[0023] In this embodiment of the invention, the fixed base 1 is used as the motion reference frame, and the fixed base 1 remains in a relatively stationary state. Figures 1 to 3 The swing shaft 3 is rotatably supported on the fixed base 1 by the bearing 7. The axis of the swing shaft 3 extends in the front-back direction. The upper end of the swing frame 2 is fixedly connected to the swing shaft 3, so that the swing frame 2 can rotate relative to the fixed base 1 with the swing shaft 3 as the rotation center.

[0024] Reference Figure 2The tube carrier 4 is detachably mounted on the swing frame 2. The tube carrier 4 is configured to load the collection tube and make the length direction of the collection tube perpendicular to the axis of the swing shaft 3. When the swing frame 2 rotates relative to the fixed seat 1, the collection tube rotates synchronously with the swing frame 2. For collection tubes of different specifications, the tube carrier 4 of the corresponding specifications can be replaced on the swing frame 2.

[0025] Reference Figure 2 and Figure 3 The drive unit 5 is mounted on the fixed base 1. The drive unit 5 includes an output shaft 51 whose axis extends in the front-rear direction. The drive unit 5 is configured to drive the output shaft 51 to rotate around its own axis. The transmission mechanism 6 includes a crank 61, a connecting rod 62 and a rocker arm 63 that are hinged in sequence. The end of the crank 61 away from the connecting rod 62 is fixedly connected to the output shaft 51. The end of the rocker arm 63 away from the connecting rod 62 is fixedly connected to the swing shaft 3.

[0026] When the drive unit 5 drives the output shaft 51 to rotate unidirectionally around its own axis, the output shaft 51 drives the swing frame 2 to reciprocate within a preset angle range around the swing shaft 3 as the center of rotation via the transmission mechanism 6. It can be understood that the transmission mechanism is a crank-rocker mechanism, wherein for each revolution of the crank 61, the crank 61 is collinear with the connecting rod 62 twice. At this time, the rocker arm 63 is in two extreme positions, giving the swing frame 2 two extreme positions. Figure 4 A schematic diagram of the structure is shown when the swing frame 2 is in one of its extreme positions.

[0027] After PPP extraction, the collection tube is mounted on the corresponding tube holder 4 with its length direction perpendicular to the axis of the swing shaft 3. The drive unit 5 is started, and the output shaft 51 rotates unidirectionally around its own axis. It drives the swing frame 2 to swing back and forth within a preset angle range around the swing shaft 3 as the rotation center through the crank 61, connecting rod 62 and rocker arm 63 in sequence. During the back and forth swinging process, the plasma on the upper layer of the blood sample is affected by its own inertia. The plasma can wash away the platelets attached to the surface of the separating gel, so that most of the platelets are peeled off from the separating gel layer, and the platelets are fully mixed with the plasma to prepare PRP. This ensures that the platelet extraction rate is high and stable.

[0028] Since the output shaft 51 and crank 61 only need to rotate in one direction at a constant speed, the rocker arm 63 and the collection tube can run continuously and smoothly without interruption, resulting in high energy efficiency, shortening the overall rocking operation time, and effectively improving the platelet extraction efficiency.

[0029] Considering that the reciprocating swing of the swing frame 2 may cause vibration of the fixed base 1, in some embodiments, refer to Figures 1 to 4 The lower end of the fixed base 1 is provided with a foot pad 13, which can be made of rubber to achieve the function of vibration reduction and cushioning.

[0030] In some embodiments, refer to Figure 2 and Figure 3 The swing shaft 3 is rotatably supported on the fixed base 1 by two bearings 7. The two bearings 7 are arranged at intervals along the axis of the swing shaft 3. The bearings 7 serve as support points for the swing shaft 3 and the attached swing frame 2, tube holder 4 and collection tube. The two bearings 7 can provide two support points for the swing shaft 3 to prevent the swing shaft 3 from deflecting up, down, left, or right.

[0031] In one embodiment, two bearings 7 are located in front of and behind the swing frame 2, respectively, which enables the swing frame 2 to swing stably.

[0032] In another embodiment, reference is made to... Figure 3 Both bearings 7 are located behind the swing frame 2. The position of the rocker arm 63 connected to the swing shaft 3 is located between the two bearings 7, which can ensure that the rocker arm 63 transmits the swing shaft 3 more accurately. Moreover, there is no support point in front of the swing frame 2, which expands the operating space around the tube rack 4, making it easier to disassemble and install the tube rack 4, and also making it easier to pick up and put down the collection tube.

[0033] In some embodiments, refer to Figure 2 and Figure 3 The fixed base 1 includes a first support plate 11 and a second support plate 12 arranged at intervals in the front-back direction. The swing shaft 3 is rotatably supported on the first support plate 11 and the second support plate 12 by two bearings 7 respectively. The first support plate 11 and the second support plate 12 both extend in the up-down direction and the left-right direction. The space between the first support plate 11 and the second support plate 12 defines the accommodating space for the transmission mechanism 6, preventing the crank 61, connecting rod 62 or rocker arm 63 from being interfered with by other components during the movement.

[0034] In addition, refer to Figure 1 The fixed base 1 also includes a housing, which encloses the first support plate 11, the second support plate 12, the drive unit 5 and the transmission mechanism 6 in the internal space of the housing, preventing the crank 61, the connecting rod 62 or the rocker arm 63 from being disturbed by the external environment during the movement.

[0035] In some embodiments, refer to Figure 2 and Figure 3 The length directions of crank 61, connecting rod 62 and rocker arm 63 are all perpendicular to the front-back direction, that is, perpendicular to the axis of swing shaft 3. Since the axis of output shaft 51 also extends in the front-back direction, it ensures that output shaft 51 can efficiently transmit torque to swing shaft 3, thereby improving the energy efficiency of drive unit 5.

[0036] In some embodiments, refer to Figure 3 and Figure 5The tube carrier 4 includes a connecting part 41 and a loading groove 42. The connecting part 41 is detachably connected to the swing frame 2. The loading groove 42 is used to position and load the collection tube. The extending direction of the loading groove 42 is perpendicular to the axis of the swing shaft 3, ensuring that the length direction of the collection tube loaded in the loading groove 42 is perpendicular to the axis of the swing shaft 3.

[0037] Reference Figure 5 In some embodiments of this utility model, the tube carrier 4 further includes a support portion 43 and a radial constraint portion 44. The support portion 43 is used to support the collection tube upward and limit the collection tube in the vertical direction. The radial constraint portion 44 is used to press and constrain the side wall of the collection tube in the radial direction to prevent the collection tube from easily detaching from the tube carrier 4 or falling off the tube carrier 4. The loading groove 42 is formed by the support portion 43 and the radial constraint portion 44, thereby forming a firm constraint on the collection tube.

[0038] In some embodiments, the radial constraint part 44 has an observation window 45 at a position on a portion of the side wall of the corresponding collection tube. The observation window 45 is connected to the loading groove 42, and the observation window 45 facilitates the operator to observe the internal condition of the collection tube.

[0039] It is understandable that the radial constraint part 44 has a certain degree of elasticity. Under the squeezing action of the collection tube, it can undergo moderate deformation at the observation window 45. At the same time, it can restore its own shape after the squeezing action disappears. This makes it convenient for the collection tube to be inserted into the loading slot 42 and also convenient for the collection tube to be removed from the loading slot 42.

[0040] Reference Figure 2 and Figure 4 In some embodiments, multiple tube racks 4 are provided on both the left and right sides of the swing frame 2, so that the separation and extraction instrument can load multiple collection tubes at the same time, thereby improving the efficiency of operation.

[0041] In some embodiments, the drive unit 5 is specifically a stepper motor. Through extensive experimental verification, the rotational speed of the drive output shaft 51 of the drive unit 5 is set to 240~400 rpm, the duration is set to 0.5~2 min, and the angle of the reciprocating swing of the swing frame 2 is set to less than or equal to 60°. That is, the included angle between the two extreme positions of the swing frame 2 is less than or equal to 60°. The tube rack 4 can be selected to load collection tubes of 10~30ml specifications. By controlling the rotational speed and duration of the stepper motor drive output shaft 51, the plasma washing force and the number of flushing times are indirectly controlled to maximize platelet extraction.

[0042] The technical features of the above embodiments can be combined in any way. For the sake of brevity, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0043] Of course, this utility model is not limited to the above-described embodiments. Those skilled in the art can make equivalent modifications or substitutions without departing from the spirit of this utility model. All such equivalent modifications or substitutions are included within the scope defined by the claims of this application.

Claims

1. A platelet separation and extraction instrument for preparing PRP, characterized in that, include: Fixed base; The swing shaft is rotatably supported on the fixed base by bearings, and the axis of the swing shaft extends in the front-to-back direction; The swing frame is fixedly connected to the swing shaft at its upper end; A tube carrier is detachably mounted on the swing frame, the tube carrier being configured to load a collection tube and with the length direction of the collection tube perpendicular to the axis of the swing shaft; A drive unit is disposed on the fixed base. The drive unit includes an output shaft whose axis extends in the front-rear direction. The drive unit is configured to drive the output shaft to rotate about its own axis. A transmission mechanism includes a crank, a connecting rod, and a rocker arm that are hinged in sequence. The end of the crank arm away from the connecting rod is fixedly connected to the output shaft, and the end of the rocker arm away from the connecting rod is fixedly connected to the swing shaft. When the drive unit drives the output shaft to rotate unidirectionally around its own axis, the output shaft drives the swing frame to swing back and forth within a preset angle range around the swing shaft as the rotation center through the transmission mechanism.

2. The platelet separation and extraction apparatus for preparing PRP according to claim 1, characterized in that, The swing shaft is rotatably supported on the fixed base by two bearings. The two bearings are arranged at intervals along the axis of the swing shaft. The two bearings are located at the front and rear of the swing frame, respectively, or both bearings are located at the rear of the swing frame.

3. The platelet separation and extraction apparatus for preparing PRP according to claim 2, characterized in that, Both bearings are located behind the swing frame, and the rocker arm connected to the swing shaft is located between the two bearings.

4. The platelet separation and extraction apparatus for preparing PRP according to claim 3, characterized in that, The fixed base includes a first support plate and a second support plate arranged at intervals in the front-back direction, and the swing shaft is rotatably supported on the first support plate and the second support plate by two bearings respectively.

5. The platelet separation and extraction apparatus for preparing PRP according to claim 1, characterized in that, The length directions of the crank, the connecting rod, and the rocker arm are all perpendicular to the front-to-back direction.

6. The platelet separation and extraction apparatus for preparing PRP according to claim 1, characterized in that, The tube carrier includes a connecting part and a loading slot. The connecting part is detachably connected to the swing frame. The extending direction of the loading slot is perpendicular to the axis of the swing shaft. The loading slot is used to position and load the collection tube.

7. The platelet separation and extraction apparatus for preparing PRP according to claim 6, characterized in that, The carrier tube rack also includes a support portion and a radial constraint portion. The support portion is used to support the collection tube, and the radial constraint portion is used to press and constrain the side wall of the collection tube radially. The loading groove is formed by the support portion and the radial constraint portion.

8. The platelet separation and extraction apparatus for preparing PRP according to claim 7, characterized in that, The radial constraint part has an observation window at a position corresponding to a portion of the side wall of the acquisition tube, and the observation window is connected to the loading slot.

9. The platelet separation and extraction apparatus for preparing PRP according to claim 1, characterized in that, Multiple tube racks are provided on both the left and right sides of the swing frame.

10. The platelet separation and extraction apparatus for preparing PRP according to claim 1, characterized in that, The driving unit is a stepper motor, and the speed at which the driving unit drives the output shaft is 240~400 rpm. The angle of reciprocating swing of the swing frame is less than or equal to 60°.

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