An automated processing module with an envelope recovery section and a biological sample processing system

Abstract

The utility model discloses an automatic processing module and biological sample processing system containing sealing membrane recovery part belong to medical instrument technical field, including the transfer module of being located in the upper area and the operation area of being located below it, and the operation area contains transfer buffer area, can receive and buffer the different type consumables of waiting transfer, and the encapsulation area of sealing membrane operation can, and the composite drawer of composite drawer configuration area contains consumable recovery subarea and diaphragm loading subarea, and transfer module can transfer at least part consumables in transfer buffer area to encapsulation area, and can transfer diaphragm from diaphragm loading subarea to encapsulation area, and the consumable of encapsulation area can be diaphragm film -coated sealed, and transfer module can transfer the consumable after sealing to the consumable recovery subarea of composite drawer and concentrate recovery, and the space utilization is improved, and the degree of automation of equipment is higher.

Description

Technical Field

[0001] This utility model relates to the field of medical device technology, specifically to an automated processing module containing a sealing film recycling section.

[0002] This utility model also relates to a biological sample processing system. Background Technology

[0003] By analyzing various types of biological samples using different methodologies, pathogens can be effectively identified, and treatment efficacy can be monitored during treatment to achieve precise treatment goals. In actual clinical applications, because this type of testing causes minimal harm to the tested individuals and poses almost no risk of cross-contamination such as aerosols, an increasing number of clinical and non-clinical samples are being collected, requiring timely and accurate test results. This necessitates the development of automated equipment. Automated analysis equipment can reduce human intervention, lower the errors that may be introduced in handling large numbers of samples, and reduce the risk of contamination to the operators themselves. At the same time, automated sample processing control is the core of emerging disciplines such as computer-aided biology, which helps to quickly transform hypothetical results into real results. Rapid and traceable testing of large numbers of samples is crucial for precise and efficient treatment combining big data and artificial intelligence systems.

[0004] Currently, key indicators for achieving efficient and accurate detection in automated testing systems include system integration and contamination control capabilities. While highly integrated automated system designs are relatively easier to implement, timely and effective contamination control within the automated system is more challenging. This is crucial for accurate detection; otherwise, there will be a high probability of false detections and reliability issues requiring retesting. JP2024086657A discloses a sample transfer procedure after opening the sample tube cap. To eliminate the step of re-closing the sample tube cap and the risk of cross-contamination during capping, it describes how the opened sample tube can be covered by a heat-sealing machine for timely sealing after use. US9588133B2 discloses a solution that centrally collects pipetting consumables and includes a receiving tray at the bottom of the pipetting consumable collection rack. After use, the pipetting consumables are inserted into the collection rack, and any residual liquid can be collected through the receiving tray. This reduces the overall risk of contamination during operation; however, in practical use, the method of uniformly inserting pipetting consumables back into the pipetting consumable rack has many problems. For example, it requires high system control precision, which is determined by the hole structure of the pipetting consumable rack. Therefore, centralized recycling of pipetting consumables often adopts the technology disclosed in patent EP2838660B1, which centrally recycles pipetting consumables into a consumable drawer through the consumable receiving hole. The consumable drawer can be lined with a plastic strip to prevent potential contamination risks during recycling. The solution disclosed in CN106872720B aims to reduce sample... The sample rack may tilt or tip over during transfer. A constraint groove structure, which fits into the bottom of the sample rack, is configured in the middle of the transfer path to minimize the risk of tipping and contamination during transfer. However, this sample rack transfer method is only suitable for large-scale, high-throughput sample processing systems. The solution disclosed in JP2010197109A focuses more on reliable transport of sample racks carrying open sample tubes. It explores speeds that may cause resonance risks during the transport of different types of sample racks and ensures the conveyor belt operates at a speed that avoids resonance risks. In automated processing systems, some consumables contain large amounts of reaction liquid. Recycling them in an open state poses a significant risk of contamination. This type of consumable can be found in patent US11385247B2. Extraction consumables are essential for automated molecular diagnostic equipment, and their efficient and low-contamination recycling directly impacts the overall contamination risk of the device. This disclosed solution is suitable for recycling empty or closed solid consumables. However, this solution also poses a risk of leakage and contamination if the membrane is punctured when recycling membrane-sealed liquid reagent kits. Although current automated processing systems have made some improvements to their detailed structures to reduce the risk of contamination at various nodes, they are not applicable to specific types of consumables, such as the extraction and recycling of consumables.

[0005] Designing a reagent kit recovery system suitable for containing large volumes of liquid is crucial for automated biological processing systems. At the same time, utilizing the remaining operating space to arrange other functional units to form more integrated automated processing modules and systems is also a pressing technical problem to be solved. Utility Model Content

[0006] The purpose of this invention is to address the aforementioned problems by providing an automated processing module and biological sample processing system with a sealing and recycling unit. By combining the sealing mechanism of the extraction kit, the amplification module, and the consumable recycling unit, the space utilization rate is improved while the degree of automation of the equipment is increased.

[0007] The technical solution adopted in this utility model is as follows: An automated processing module with a sealing film recycling section, the module including a transfer module and an operating area disposed below the transfer module; The operating area includes: A transfer buffer area, wherein consumables are carried; The packaging area is used to receive consumables transferred from the transfer buffer area using the transfer module and to perform a sealing operation. The composite drawer configuration area includes a consumable recycling sub-area and a diaphragm loading sub-area. The consumable recycling sub-area is used to receive sealed consumables transferred from the packaging area using the transfer module. The diaphragm loading sub-area contains several diaphragms, which are transferred to the packaging area by the transfer module.

[0008] Furthermore, the transfer module includes an extension beam located above the operating area and parallel to the surface of the operating area. The extension beam is vertically connected to a cross beam in the horizontal direction. The cross beam is connected to the extension beam through an extension drive mechanism. The extension drive mechanism can drive the cross beam to move along the extension direction of the extension beam. A functional module that can move along the extension direction of the cross beam is movably connected to the cross beam. The functional module is used to transfer consumables and diaphragms.

[0009] Furthermore, the functional module includes a gripper unit and a suction cup unit. Both the gripper unit and the suction cup unit can be moved up and down along the vertical direction of the operating area. The gripper unit is used to grip and transfer consumables, and the suction cup unit is used to adsorb and transfer membranes in the membrane loading sub-area.

[0010] Furthermore, the encapsulation area includes a heat-sealing module for heat-sealing the diaphragm at the opening of the consumable transferred therein.

[0011] Furthermore, the operating area also includes a centrifugation area and an amplification area; The centrifugation zone includes a centrifugation module, which is used to receive amplification consumables and perform centrifugation and mixing operations. The amplification area includes an amplification module, which receives amplification consumables transferred from the centrifugation area via the transfer module for amplification detection, and the amplification module is movably configured within the operation area.

[0012] Furthermore, the amplification module includes multiple sub-amplification sections arranged in parallel, each sub-amplification section being used to receive the amplification consumables. An optical detection element is provided on one side of each sub-amplification section, the optical detection element being used to detect the amplification consumables within the sub-amplification section.

[0013] Furthermore, the amplification module is provided with a heat cover above the multiple sub-amplification sections, and the heat cover is provided with a detection hole above each sub-amplification section that cooperates with the optical detection element; The optical detection element is slidably connected to the heat cover along the extension direction of the heat cover, and is used for the optical detection element to perform detection along the detection hole corresponding to each sub-amplification section.

[0014] Furthermore, the sub-amplification unit is equipped with a thermal circulation component that can move up and down towards or away from the thermal cover. The amplification consumable can be fitted between the thermal circulation component and the thermal cover. After receiving the amplification consumable, the sub-amplification unit uses the thermal circulation component to press the amplification consumable between the thermal cover and the thermal circulation component.

[0015] Furthermore, the amplification region includes two spaced sub-amplification regions, each of which is equipped with an amplification module. The amplification module is movably configured within the sub-amplification region and is used for sliding out or being placed into the sub-amplification region as a whole.

[0016] The second technical solution adopted by this utility model is a biological sample processing system, which includes an automated processing module containing a sealing and recovery section.

[0017] In summary, due to the adoption of the above technical solution, the beneficial effects of this utility model are: 1. This utility model arranges a transfer module in the upper area of ​​the automated processing module, and configures an operation area containing multiple functional areas below it. The transfer buffer area of ​​the operation area can receive and buffer different types of consumables to be transferred. The composite drawer of the composite drawer configuration area is equipped with a membrane loading sub-area, which can simultaneously and conveniently replenish the membranes of the consumables to be packaged. The transfer module can transfer the consumables to be packaged and the membranes to the packaging area, so that the consumables can be sealed by the membranes. Here, the transfer module includes at least two sub-functional units, namely a gripper unit and a suction cup unit, which makes the processing module more integrated and the operation and control simpler.

[0018] 2. The transfer module disclosed in this utility model includes a lifting drive mechanism that can drive the functional unit to move along the vertical substrate, and a two-dimensional drive module that can drive the functional unit to move in a plane perpendicular to the vertical direction, so that the functional unit of the transfer module can be driven to any position in a specific space to perform different consumable transfer operations.

[0019] 3. The consumable recycling sub-area of ​​the composite drawer disclosed in this utility model can be divided into multiple sub-areas, including an extraction consumable recycling sub-area and an expansion consumable recycling sub-area, so that various consumables are recycled into recycling boxes in different sub-areas, resulting in higher recycling efficiency and simpler operation. The sealing area includes a heat-sealing film block, which can use heat-sealing technology to heat-seal the film at the opening of the extraction consumable. Then, the transfer module transfers it to the extraction consumable recycling sub-area for centralized recycling. The overall control method is simple and the risk of pollution during recycling is low.

[0020] 4. The operation area disclosed in this utility model is configured with a centrifugation area and an amplification area. After centrifugation in the centrifugation area, the amplification system solution is fully and evenly distributed to the bottom of the consumable in the reagent kit. Then, it is transferred to the amplification module in the amplification area for amplification. The amplification module here includes multiple sub-amplification sections arranged in parallel, so that higher throughput amplification operations can be performed sequentially. The amplification module includes a shared hot cap and optical detection element. By driving and scanning multiple detection holes on the hot cap body, the amplification results in the amplification consumable pressed between the hot cap and the thermal cycling component are obtained, making the detection more efficient and having the effect of flexibly adjusting the detection throughput. It is more suitable for the automated detection system with non-centralized amplification consumable loading. The two spaced amplification modules are configured in spaced sub-amplification areas. The amplification modules can be pulled out or inserted as a whole, ensuring higher maintainability and simpler configuration.

[0021] 5. Finally, this utility model also discloses a biological sample processing system, which includes the aforementioned automated processing module with a sealing and recycling section, so that the liquid consumable box of the biological sample processing system can be sealed and recycled in a timely and effective manner, and the system can operate with high automation and low pollution risk in a confined space. Attached Figure Description

[0022] Figure 1 This is a view of the overall structure of one of the automated processing modules of this utility model, which includes a sealing film recycling unit; Figure 2 This is another perspective view of the overall structure of an automated processing module including a sealing film recycling unit according to this utility model; Figure 3 This is a schematic diagram of the composite drawer layout in this utility model; Figure 4 This is a structural configuration diagram of the amplification module in this utility model; Figure 5This is a structural diagram of the transfer module in this utility model; Figure 6 This is a structural diagram of the two functional units included in the transfer module of this utility model; Figure 7 This is a diagram showing the transfer of amplification consumables from the clamping unit into the amplification section in this utility model. Figure 8 This is a diagram showing the state of the transfer module being driven to retrieve consumables from the transfer buffer area in this utility model. Figure 9 This is a diagram showing the state of the transfer module being driven to transfer the diaphragm from the diaphragm loading sub-region in this utility model. Figure 10 This is a state diagram of the transfer module being driven to clamp the amplification consumables from the transfer buffer area in this utility model.

[0023] In the diagram: 100 - drawer base; 11-Transfer buffer area, 12-Extraction consumable recycling sub-area, 13-Amplification consumable recycling sub-area, 14-Patch loading sub-area, 15-Encapsulation area, 16-Centrifugation area; 170-Sub-amplification section, 171-Sub-amplification area one, 172-Sub-amplification area two, 1711-Optical detection element, 1712-Detection hole, 1713-Heat sink, 1714-Lifting drive mechanism, 1715-Amplification consumable receiving section, 1716-Cooling fan.

[0024] 20 - Functional module, 201 - Gripper drive motor, 21 - Suction cup unit, 22 - Clamping unit 31-Extension beam, 311-Extension motor, 312-Extension transmission belt, 313-Beam connecting block. 32-Extension guide rod; 33 - span beam, 331 - span beam motor, 332 - span beam drive belt. Detailed Implementation

[0025] The present invention will now be described in detail with reference to the accompanying drawings.

[0026] To make the objectives, technical solutions, and advantages of this utility model clearer, the present utility model will be further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the present utility model and are not intended to limit the present utility model.

[0027] Example 1 like Figure 1 and Figure 2As shown, this embodiment provides an automated processing module with a sealing and recovery section. The module is entirely arranged within a cuboid space. To ensure low-pollution characteristics, the module may include an outer shell structure composed of thin-walled components such as steel, glass, and plastic. This embodiment shows the basic structure of the reagent preparation module without the outer shell. A transfer module is configured at the top of the module, including a three-dimensional motion drive. An operating area is arranged in the lower region of the module in conjunction with the transfer module. The operating area can extend in two dimensions to form sub-areas capable of multiple functions. The operating area includes a transfer buffer 11, which can receive and buffer different types of consumables to be transferred. In this embodiment, the transfer buffer 11 can be configured as a lifting structure to receive different types of consumables to be processed from the top. The consumables include at least two types: extraction consumables and amplification consumables. The consumables are of various types; extraction consumables and amplification consumables can also be described as extraction kits or amplification kits, respectively. In this embodiment, the adjacent transfer buffer area 11 is configured with a sealing area 15 capable of sealing operations. The sealing area 15 is configured with a sealing unit. In this embodiment, the sealing unit is a heat-sealing film module, but it can also be other types of sealing mechanisms. The sealing unit can apply a specific temperature of heat to the consumables and the film laid on the consumables, so that at least part of the film is heat-sealed to at least part of the opening of the consumables to achieve reliable heat sealing of the open consumables. To ensure ease of operation and drive reliability, a composite drawer configuration area is also arranged in the operation area. The composite drawer configuration area is configured with a composite drawer that can be pulled out of the module body range. The bottom of the composite drawer is configured with a slide rail or roller structure to reduce the resistance during the operation of pulling out the drawer. Figure 3As shown, the composite drawer includes a consumable recycling sub-area and a membrane loading sub-area 14. To more efficiently and reliably recycle different types of consumables, the consumable recycling sub-area further includes an amplification consumable recycling sub-area 13 and an extraction consumable recycling sub-area 12. Thus, by pulling out the composite drawer, the recycled extraction or amplification consumables can be centrally recycled and processed. Furthermore, membrane-type consumables can be promptly replenished within the membrane loading sub-area 14. In this embodiment, the composite drawer includes a drawer base 100. An extraction and recycling basket detachably connected to the drawer base 100 is configured within the extraction consumable recycling sub-area 12. To reduce the risk of recycling contamination and achieve rapid packaging processing, the extraction... The recycling basket can be lined with a plastic bag. Similarly, the expansion consumables recycling sub-area 13 is also equipped with an expansion recycling basket. The membrane loading sub-area 14 is equipped with a membrane supply unit. Multiple membrane limiting members are arranged around the membrane supply unit to accurately define the position of the membrane. A pressure block that can slide up and down along at least part of the limiting members is also arranged on the upper part of the membrane supply unit, which can press down part of the edge of the membrane received in the membrane supply unit, so that the membrane can be supplied neatly and reliably. A weight sensor can also be arranged at the bottom of the membrane supply unit to detect whether the membrane transfer is successful each time and to know in time whether there is enough membrane. The overall operation is simple and only requires a composite drawer to meet the requirements. The membrane can be a metal membrane such as aluminum foil or gold foil, or a plastic membrane; the type is not limited. The operating area also includes an amplification zone and a centrifugation zone 16. Centrifugation zone 16 is equipped with a centrifuge, which contains several pairs of opposing centrifuge racks. The centrifuge drive motor drives the centrifuge racks to operate in a set rotation mode to centrifuge the received amplification consumables. This ensures that the various reagents and analytes within the amplification consumables are thoroughly mixed, and that the amplification system is evenly distributed to the bottom of the consumables within the reagent kit. Air bubbles and other interfering substances in the system are also effectively removed. To ensure proper centrifugation of the modules during operation... Other functional units within the centrifuge are largely unaffected. The centrifuge is mounted on a vibration-damping base or other vibration-damping components. In this embodiment, the amplification zone includes two spaced-apart sub-amplification zones 171 and 172, each equipped with an amplification module. This enables continuous and batch amplification detection, ensuring the high efficiency of the system. In this embodiment, the amplification zone and the sealing and recovery unit are integrated into the same automated processing module, allowing the amplification consumables to be recovered promptly and efficiently. Meanwhile, the extraction kits used only require a heat-sealing operation, resulting in short exposure time, no contamination, and improved integration of the automated processing module.

[0028] like Figure 4As shown, the amplification module in sub-amplification area 171 is equipped with a handle at its end, allowing the amplification module to be pulled out or inserted as a whole during assembly and maintenance, simplifying the configuration. The amplification module includes multiple sub-amplification sections 170 arranged in parallel. Each sub-amplification section includes a thermal circulation component that can be driven to move up and down by a lifting drive mechanism 1714. The thermal circulation component can be raised or lowered by the rotational movement of the lifting drive motor of the lifting drive mechanism 1714. To ensure the compact operation of the lifting drive mechanism 1714, the output of the drive motor is connected to a horizontally arranged transmission screw to rotate. The rotational movement is converted into the lifting movement of the thermal circulation component through the transmission mechanism. Multiple sub-amplification sections can share an optical detection element 1711. Multiple sub-amplification sections also share a fixedly configured heat cover. The heat cover is equipped with multiple detection holes 1712 penetrating its body. Here, the multiple detection holes 1712 are arranged linearly and at intervals on the heat cover. The optical detection element 1711 is connected to... In the optical drive mechanism, a detection slide rail is arranged along the length of the hot cover on the hot cover. The optical detection element 1711 is fitted with the detection slide rail for displacement limiting of the optical detection element 1711. The output of the detection motor is connected to the detection drive wheel, and a detection transmission wheel is arranged at intervals along the length of the hot cover. A detection transmission belt is wound between the detection drive wheel and the detection transmission wheel. One position of the detection transmission belt is fixedly connected to the optical detection element 1711. In this way, the detection motor can drive the optical detection element 1711 to reciprocate along the detection slide rail. The lifting drive mechanism can drive the amplification consumables held in the thermal cycling assembly to be pressed between the hot cover and the thermal cycling assembly. As the optical detection element 1711 traverses the scanning detection hole 1712 at intervals, the fluorescence amplification result in the amplification consumables pressed between the hot cover and the thermal cycling assembly can be obtained. The heat sink 1713 in the thermal cycling assembly can dissipate waste heat in time during the thermal cycling amplification operation to reliably execute the thermal cycling amplification reaction.

[0029] like Figure 5 and Figure 6As shown, a transfer module for multiple sub-functional units and a drive mechanism for driving the functional units to move are included. The transfer module includes a lifting drive mechanism that can move the sub-functional units up and down on a vertical base plate arranged in the vertical direction of the operating area. The lifting drive mechanism includes a lifting motor, the output end of which is connected to a lifting screw. The screw slider is threaded onto the screw and then driven to the sub-functional unit. At the same time, the screw slider is engaged with a slide rail arranged on the vertical base plate to provide displacement direction limitation. The operating height of the functional unit is changed by driving the lifting motor. In this embodiment, the sub-functional units and the vertical base plate together constitute a functional module 20. The functional module 20 also includes a vacuum pump that can provide negative pressure for the suction cup unit. The two-dimensional drive module drives the sub-functional units to move in a plane perpendicular to the vertical direction. The two-dimensional drive module includes an extension beam 31 and an extension drive mechanism disposed thereon. The extension drive mechanism includes an extension motor 311. The output of the extension motor 311 is connected to an extension drive wheel. Extension driven wheels are arranged at preset intervals in the extension direction of the extension beam 31. An extension transmission belt 312 is wound and strung between the two wheels. A fixed connection block 313 is provided at one position to connect the beam connecting the crossbeam 33, so that the output of the extension drive mechanism connects the crossbeam 33 and drives the crossbeam 33 to move along the extension direction of the extension beam 31. In order to reduce the movement resistance of the crossbeam 33, the end of the crossbeam 33 is also fitted and connected to the extension slide rail fixedly connected to the extension beam 31. The crossbeam is also equipped with a crossbeam drive mechanism, which outputs and connects to the vertical base plate and drives it to move along the extension direction of the crossbeam, and synchronously drives the functional module 20 to move. In this embodiment, a crossbeam motor 331 is provided at the top of one end of the crossbeam 33, and its output is connected to the crossbeam drive wheel below. A crossbeam transmission wheel is arranged at a predetermined distance from the drive wheel in the extension direction of the crossbeam 33. A crossbeam transmission belt 332 is wound around the two wheels. A vertical base plate is fixedly connected to one position of the crossbeam transmission belt 332, thereby driving the vertical base plate to slide along the crossbeam slide rail on the crossbeam 33. In order to reliably support the functional module 20, an extension guide rod 32 is also arranged parallel to the extension beam at a distance. One end of the crossbeam 33 is also rotatably connected to the extension guide rod 32. In this way, the sub-functional unit can be driven to move at any position in a specific three-dimensional space. The structure of the sub-functional unit is as follows: Figure 6 As shown, it includes a clamping unit 22 and a suction cup unit 21. The clamping unit 22 includes a gripper drive motor 201. The gripper drive motor 201 outputs a drive connection to two opposing grippers so that they can move closer or further apart. The suction cup unit 21 is connected to a vacuum pump and can generate a negative pressure drive suction force at the negative pressure suction cup.

[0030] like Figure 7The diagram shows the state of the clamping unit 22 transferring amplification consumables into the sub-amplification section. The opposing grippers of the clamping unit 22 in the transfer module can approach each other to clamp the amplification consumables, and then be driven to move to the amplification module. The sub-amplification section can be driven to extend the thermal cycling component outside the main body of the amplification module. The top of the thermal cycling component is equipped with an amplification consumable receiving section 1715, and the bottom is equipped with a heat source and a heat sink 1713. The heat sink 1713 is arranged in the air duct and a cooling fan 1716 is arranged at the end of the air duct, so that the amplification consumables received in the thermal cycling component can be controlled to operate in a suitable temperature control mode, which can be a constant temperature mode or a high and low temperature variable temperature cycling mode.

[0031] like Figure 8 The diagram shows the state of the automated processing module's transfer module being driven to retrieve consumables from the transfer buffer. During a certain time period, the transfer buffer 11 is configured with retrieval consumables. At this time, the retrieval consumables are open, indicating that the retrieval operation has been completed. The functional module 20 of the transfer module can be driven to move above the transfer buffer 11. The sub-functional unit can be driven to descend, allowing the gripping unit's opposing claw to approach and clamp the retrieval consumables, which are then transferred to the encapsulation area. After the consumable transfer is completed, the functional module 20 can be driven to move above the diaphragm loading sub-area 14, combined with... Figure 9 The sub-functional unit can be driven to descend, bringing the suction cup unit closer to the membrane. Under the action of the connected vacuum pump, the negative pressure suction cup of the suction cup unit can adsorb the membrane in the membrane loading sub-area 14. With the membrane detection device configured in the transfer module, the status of the membrane transferred by the suction cup unit can be monitored in real time to ensure the reliable operation of the transfer module. The suction cup unit can adsorb and transfer the membrane to the encapsulation area, and make the membrane cover the upper opening of the amplification consumable. In this way, the heat-sealing membrane block in the encapsulation area heat-seales the membrane at the opening of the extraction consumable. The transfer module transfers the sealed extraction consumable to the extraction consumable recycling sub-area to complete the recycling of the extraction consumable. During this process, the extraction consumable does not perform any functional operation, the risk of contamination is low, and the opening time of the extraction consumable is short, so it can be quickly and with low pollution for centralized recycling.

[0032] like Figure 10 The diagram shows the state of the automated processing module's transfer module being driven to clamp the amplification consumables from the transfer buffer; in conjunction with... Figure 8During different time periods, amplification consumables can be configured in the transfer buffer 11. The amplification consumables are in a closed state with a cap, containing amplification fluid containing the amplification reagents and test analytes that have been transferred. The functional module 20 of the transfer module can be driven to move above the transfer buffer 11, and the sub-functional unit can be driven to move downward so that the gripping unit's opposing claw can approach and clamp the amplification consumables. In order to ensure accurate and efficient amplification, the gripping unit can transfer the amplification consumables to the centrifugation area and load the amplification consumables onto the centrifuge to perform centrifugation. After centrifugation, the gripping unit can clamp the amplification consumables and configure them in one of the sub-amplification sections of the amplification area to perform amplification detection. Of course, the gripping unit can configure amplification consumables in at least two sub-amplification sections in a basically continuous and sequential manner to make the amplification detection more efficient. The amplification consumables that have completed amplification detection can be removed by the gripping unit and finally transferred to the amplification consumables recovery sub-area to complete the recovery operation.

[0033] Example 2 A biological sample processing system includes an automated processing module with a sealing and recycling section as described in Embodiment 1. The module receives and caches different types of consumables from other functional modules of the biological sample processing system through a transfer buffer 11. This embodiment may include two types of consumables: extraction consumables and amplification consumables. Other structures and functions will not be described in detail here.

[0034] This document uses specific embodiments to illustrate the principles and implementation methods of this utility model. The descriptions of the embodiments above are only for the purpose of helping to understand the method and core ideas of this utility model. It should be noted that for those skilled in the art, several improvements and modifications can be made to this utility model without departing from the principles of this utility model, and these improvements and modifications also fall within the protection scope of the claims of this utility model.

[0035] In the description of this utility model, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings, or the orientation or positional relationship commonly used when the utility model product is in use. They are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this utility model.

[0036] In the description of this utility model, it should also be noted that, unless otherwise explicitly specified and limited, the terms "set up," "connected," and "linked" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model based on the specific circumstances.

Claims

1. An automated processing module including a sealing film recycling unit, characterized in that, The module includes a transfer module and an operation area disposed below the transfer module; The operating area includes: A transfer buffer area, wherein consumables are carried; The packaging area is used to receive consumables transferred from the transfer buffer area using the transfer module and to perform a sealing operation. The composite drawer configuration area includes a consumable recycling sub-area and a diaphragm loading sub-area. The consumable recycling sub-area is used to receive sealed consumables transferred from the packaging area using the transfer module. The diaphragm loading sub-area contains several diaphragms, which are transferred to the packaging area by the transfer module.

2. The automated processing module including a sealing film recycling unit according to claim 1, characterized in that, The transfer module includes an extension beam located above the operating area and parallel to the surface of the operating area. The extension beam is vertically connected to a cross beam in the horizontal direction. The cross beam is connected to the extension beam through an extension drive mechanism. The extension drive mechanism can drive the cross beam to move along the extension direction of the extension beam. A functional module that can move along the extension direction of the cross beam is movably connected to the cross beam. The functional module is used to transfer consumables and diaphragms.

3. The automated processing module including a sealing film recycling unit according to claim 2, characterized in that, The functional module includes a gripper unit and a suction cup unit. Both the gripper unit and the suction cup unit can move up and down along the vertical direction of the operating area. The gripper unit is used to grip and transfer consumables, and the suction cup unit is used to adsorb and transfer membranes in the membrane loading sub-area.

4. The automated processing module including a sealing film recycling unit according to claim 1, characterized in that, The encapsulation area includes a heat-sealing module for heat-sealing the diaphragm at the opening of the consumable transferred therein.

5. An automated processing module including a sealing film recycling unit according to claim 1, characterized in that, The operating area also includes a centrifugation area and an amplification area; The centrifugation zone includes a centrifugation module, which is used to receive amplification consumables and perform centrifugation and mixing operations. The amplification area includes an amplification module, which receives amplification consumables transferred from the centrifugation area via the transfer module for amplification detection, and the amplification module is movably configured within the operation area.

6. An automated processing module including a sealing film recycling unit according to claim 5, characterized in that, The amplification module includes multiple sub-amplification sections arranged in parallel, each sub-amplification section being used to receive the amplification consumables. An optical detection element is provided on one side of each sub-amplification section, and the optical detection element is used to perform amplification detection in conjunction with the amplification consumables within the sub-amplification section.

7. An automated processing module including a sealing film recycling unit according to claim 6, characterized in that, The amplification module is provided with a heat cover above the multiple sub-amplification sections, and the heat cover is provided with a detection hole above each sub-amplification section to cooperate with the optical detection element; The optical detection element is slidably connected to the heat cover along the extension direction of the heat cover, and is used for the optical detection element to perform detection along the detection hole corresponding to each sub-amplification section.

8. An automated processing module including a sealing film recycling unit according to claim 7, characterized in that, The sub-amplification unit is equipped with a thermal circulation component that can move up and down towards or away from the thermal cover. The amplification consumable can be fitted between the thermal circulation component and the thermal cover. After receiving the amplification consumable, the sub-amplification unit uses the thermal circulation component to press the amplification consumable between the thermal cover and the thermal circulation component.

9. An automated processing module including a sealing film recycling unit according to claim 5, characterized in that, The amplification region includes two spaced sub-amplification regions, each containing an amplification module. The amplification module is movably positioned within the sub-amplification region and is used for sliding out or being placed into the sub-amplification region as a whole.

10. A biological sample processing system, characterized in that, The system includes an automated processing module with a sealing film recycling section as described in any one of claims 1 to 9.

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