A low-temperature constant-pressure sealing storage device for stem cell cryopreservation

CN224767341UActive Publication Date: 2026-09-18BETACURE MEDICAL INC +1
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Patent Information

Application Number
CN202522428036.6
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-11-17
Publication Date
2026-09-18
Estimated Expiration
2035-11-17

AI Technical Summary

Technical Problem

[0003]目前液氮虹吸管结霜堵塞问题是由环境水汽反复侵入引起的渐进性故障,当装置频繁开启时,外界潮湿空气接触超低温管壁会持续形成霜层,这些霜层在狭窄的虹吸管内逐渐堆积,最终导致通道变窄甚至完全堵塞,直至最终影响样本保存环境

Benefits of technology

[0012] Compared with the prior art, the beneficial effects of this utility model are as follows: the cleaning component set at the bottom of the sealing cover adopts a rotary linkage design, which automatically drives the cleaning brush to scrape along the outer wall of the siphon tube in a circumferential manner each time the cover is closed, thoroughly removing the newly formed frost layer. In conjunction with the directional flow structure of the collection component, the scraped frost debris is collected and treated in a concentrated manner to prevent secondary adhesion. At the same time, the double sealing barrier formed by the sealing ring and the heat preservation tank reduces the chance of external moisture intrusion, blocks the vicious cycle of gradual accumulation of frost layer, and ensures that the siphon tube remains unobstructed for a long time.

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Abstract

The utility model provides a kind of low-temperature constant-pressure sealing storage device for stem cell cryopreservation, belong to the technical field of medical low-temperature processing device, including bearing mechanism, including shell, collection subassembly being arranged in the shell bottom, and heat preservation tank being fixedly installed in the shell inner chamber;Sealing mechanism, including the sealing cover of screw thread installation in the shell top, cleaning assembly being arranged in the sealing cover bottom.The utility model is scraped by the cleaning assembly of sealing cover bottom setting using rotation linkage design, and the circumferential scraping of cleaning brush strip along siphon pipe body outer wall is automatically driven in each time cover action, and newly formed frost layer is thoroughly removed, and the directional flow guide structure of collection subassembly is handled, and the frost chip scraped off is concentrated and received, prevent secondary attachment, and the double sealing barrier formed by sealing ring and heat preservation tank reduces the opportunity of outside water vapor intrusion, and the vicious cycle of frost layer progressive accumulation is blocked, to ensure that siphon pipe keeps open state for a long time.
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Description

Technical Field

[0001] This utility model belongs to the technical field of medical cryogenic processing devices, specifically relating to a cryogenic constant pressure sealed storage device for stem cell cryopreservation. Background Technology

[0002] Low-temperature constant-pressure sealed storage device for stem cell cryopreservation is a professional biological storage device that uses liquid nitrogen or mechanical refrigeration technology to ensure that stem cells are protected from temperature fluctuations, ice crystal damage and external contamination during long-term preservation in an ultra-low temperature environment through a precision pressure regulation system and multiple sealing protection designs.

[0003] Currently, the problem of frost blockage in liquid nitrogen siphon tubes is a progressive failure caused by repeated intrusion of environmental moisture. When the device is frequently turned on, the humid air from the outside will continuously form frost layers when it comes into contact with the ultra-low temperature tube wall. These frost layers gradually accumulate in the narrow siphon tube, eventually causing the channel to narrow or even completely block it, until it finally affects the sample preservation environment. Utility Model Content

[0004] The purpose of this invention is to provide a low-temperature constant-pressure sealed storage device for stem cell cryopreservation, which aims to solve the problems mentioned in the background art.

[0005] To achieve the above objectives, this utility model provides the following technical solution: A cryopreservation device for stem cell cryopreservation, comprising: The support mechanism includes a housing, a collection assembly disposed at the bottom of the housing, and an insulated container fixedly installed inside the housing. The sealing mechanism includes a sealing cap threaded onto the top of the housing, a cleaning assembly disposed at the bottom of the sealing cap, a sealing ring fixedly mounted at the bottom of the sealing cap, and a locking assembly disposed on the outside of the housing; The cleaning assembly includes a guide rail fixedly installed at the bottom of the sealing cover, a fixing block fixedly installed in the inner cavity of the guide rail, a return spring fixedly installed on the outside of the fixing block, and a connecting piece fixedly installed at the end of the return spring.

[0006] As a preferred embodiment of this utility model, the cleaning assembly further includes a telescopic block fixedly installed on the outside of the connecting piece, an arc-shaped piece fixedly installed on the bottom of the telescopic block, and a cleaning brush strip fixedly installed at a vertical angle on the outside of the arc-shaped piece.

[0007] As a preferred embodiment of the present invention, the supporting mechanism further includes a hollow cavity formed in the inner cavity of the outer shell, and a siphon tube body fixedly installed inside the hollow cavity.

[0008] In a preferred embodiment of this invention, the outer side of the cleaning brush bar contacts the outer side of the siphon tube body to remove frost and debris.

[0009] As a preferred embodiment of this utility model, the collection assembly includes a base fixedly installed at the bottom of the outer shell, a water-blocking strip fixedly installed in the inner cavity of the base, a guide slot opened at the top of the water-blocking strip, and a collection box fixedly installed at the bottom of the water-blocking strip.

[0010] As a preferred embodiment of this utility model, the locking assembly includes a bearing fixedly installed on the outside of the housing, a positioning sleeve hinged to the outside of the bearing, and a limiting rod fixedly installed on the outside of the positioning sleeve.

[0011] As a preferred embodiment of this utility model, the locking assembly further includes a locking rod fixedly installed on the outside of the housing, and a slot formed at the bottom of the limiting rod. The locking rod is movably engaged in the inner cavity of the slot to achieve fixation after the positioning sleeve is unfolded.

[0012] Compared with the prior art, the beneficial effects of this utility model are as follows: the cleaning component set at the bottom of the sealing cover adopts a rotary linkage design, which automatically drives the cleaning brush to scrape along the outer wall of the siphon tube in a circumferential manner each time the cover is closed, thoroughly removing the newly formed frost layer. In conjunction with the directional flow structure of the collection component, the scraped frost debris is collected and treated in a concentrated manner to prevent secondary adhesion. At the same time, the double sealing barrier formed by the sealing ring and the heat preservation tank reduces the chance of external moisture intrusion, blocks the vicious cycle of gradual accumulation of frost layer, and ensures that the siphon tube remains unobstructed for a long time. Attached Figure Description

[0013] To more clearly illustrate the technical solutions of the embodiments of this utility model, the drawings used in the description of the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort. Among them: Figure 1 This is a schematic diagram of the overall structure of this utility model; Figure 2 This is a schematic diagram showing the disassembly of the sealing mechanism of this utility model; Figure 3 This is a schematic diagram of the sealing mechanism of this utility model; Figure 4 This is a schematic diagram of the collection component structure of this utility model.

[0014] In the picture: 100. Supporting mechanism; 110. Outer shell; 120. Collection assembly; 121. Base; 122. Water baffle; 123. Guide slot; 124. Collection box; 130. Insulated tank; 140. Hollow chamber; 150. Siphon tube body; 200. Sealing mechanism; 210. Sealing cover; 220. Cleaning assembly; 221. Guide rail; 222. Fixing block; 223. Return spring; 224. Connecting piece; 225. Telescopic block; 226. Arc-shaped piece; 227. Cleaning brush strip; 230. Sealing ring sleeve; 240. Locking assembly; 241. Shaft seat; 242. Positioning sleeve; 243. Limiting rod; 244. Locking rod; 245. Locking groove. Detailed Implementation

[0015] To make the above-mentioned objectives, features and advantages of this utility model more apparent and understandable, the specific embodiments of this utility model will be described in detail below with reference to the accompanying drawings.

[0016] Many specific details are set forth in the following description in order to provide a full understanding of the present invention. However, the present invention may also be implemented in other ways different from those described herein. Those skilled in the art can make similar extensions without departing from the spirit of the present invention. Therefore, the present invention is not limited to the specific embodiments disclosed below.

[0017] Secondly, the term "an embodiment" or "embodiment" as used herein refers to a specific feature, structure, or characteristic that may be included in at least one implementation of the present invention. The phrase "in one embodiment" appearing in different places in this specification does not necessarily refer to the same embodiment, nor is it a single or selective embodiment that excludes other embodiments.

[0018] Example Reference Figures 1-4 This embodiment of the present invention provides a low-temperature constant-pressure sealed storage device for stem cell cryopreservation, comprising: The support mechanism 100 includes a housing 110, a collection assembly 120 disposed at the bottom of the housing 110, and a heat preservation tank 130 fixedly installed in the inner cavity of the housing 110. The sealing mechanism 200 includes a sealing cover 210 threadedly mounted on the top of the housing 110, a cleaning assembly 220 disposed at the bottom of the sealing cover 210, a sealing ring 230 fixedly mounted at the bottom of the sealing cover 210, and a locking assembly 240 disposed on the outside of the housing 110. The cleaning assembly 220 includes a guide rail 221 fixedly installed at the bottom of the sealing cover 210, a fixing block 222 fixedly installed in the inner cavity of the guide rail 221, a return spring 223 fixedly installed on the outside of the fixing block 222, and a connecting piece 224 fixedly installed at the end of the return spring 223.

[0019] The supporting mechanism 100 achieves the stability of the overall structure of the device and the directional collection of condensate through the cooperation of the outer shell 110 and the collection component 120; the sealing mechanism 200 uses a threaded sealing cover 210 and a movable cleaning component 220 to work together to provide a self-cleaning function while ensuring sealing; the cleaning component 220 uses the linkage design of the guide rail 221 and the return spring 223 to make the cleaning action and the opening and closing of the cover completed simultaneously, which simplifies the operation process and ensures the cleaning effect. The overall structure is compact and highly reliable.

[0020] Specifically, the cleaning component 220 also includes a telescopic block 225 fixedly installed on the outside of the connecting piece 224, an arc-shaped piece 226 fixedly installed on the bottom of the telescopic block 225, and a cleaning brush strip 227 fixedly installed at a vertical angle on the outside of the arc-shaped piece 226.

[0021] The design of the telescopic block 225 and the arc-shaped plate 226 allows the cleaning brush 227 to adaptively fit the outer wall of the siphon tube 150, ensuring uniform force and comprehensive coverage during cleaning. The vertical installation of the cleaning brush 227 can effectively scrape off frost and prevent secondary adhesion, while reducing wear on the tube surface and extending the service life of the device.

[0022] Furthermore, the carrier mechanism 100 also includes a hollow chamber 140 formed in the inner cavity of the outer shell 110, and a siphon tube body 150 fixedly installed inside the hollow chamber 140. The outer side of the cleaning brush 227 contacts the outer side of the siphon tube body 150 to scrape off frost.

[0023] The hollow chamber 140 provides a stable installation environment for the siphon tube 150, ensuring that its low-temperature performance is not affected by external factors. The fixed installation method of the siphon tube 150 avoids displacement caused by vibration or temperature changes, ensuring the continuity and stability of liquid nitrogen delivery, thereby maintaining a constant temperature and pressure environment for stem cell storage. The contact design between the cleaning brush 227 and the siphon tube 150 ensures that frost is automatically scraped off each time the lid is closed, without manual intervention. This structure effectively avoids the problem of reduced flow cross-section caused by frost accumulation, ensuring the efficiency of liquid nitrogen replenishment, while reducing the risk of failure caused by frost blockage.

[0024] Preferably, the collection assembly 120 includes a base 121 fixedly installed at the bottom of the housing 110, a water-blocking strip 122 fixedly installed in the inner cavity of the base 121, a guide slot 123 opened at the top of the water-blocking strip 122, and a collection box 124 fixedly installed at the bottom of the water-blocking strip 122.

[0025] The design of the base 121 and the water-blocking strip 122 can guide the scraped frost debris into the collection box 124 in a directional manner, avoiding the retention of condensate water and affecting the performance of the device; the guide slot 123 ensures that the frost debris is collected efficiently, and the detachable structure of the collection box 124 makes it easy to clean regularly, significantly improving the convenience of maintenance.

[0026] Furthermore, the locking assembly 240 includes a bearing 241 fixedly installed on the outside of the housing 110, a positioning sleeve 242 hinged to the outside of the bearing 241, and a limiting rod 243 fixedly installed on the outside of the positioning sleeve 242. The locking assembly 240 also includes a locking rod 244 fixedly installed on the outside of the housing 110, and a slot 245 opened at the bottom of the limiting rod 243. The locking rod 244 is movably locked in the inner cavity of the slot 245 to achieve fixation after the positioning sleeve 242 is unfolded.

[0027] The hinged design of the bearing seat 241 and the positioning sleeve 242 enables the locking assembly 240 to have flexible unfolding and folding functions; the limiting rod 243 provides stable support after unfolding, ensuring that the sealing cover 210 remains firmly fixed in the closed state, preventing temperature fluctuations or sealing failure due to accidental opening; the cooperating structure of the locking rod 244 and the slot 245 enables the locking assembly 240 to achieve a self-locking function after unfolding, avoiding accidental loosening due to vibration or external force; this design, while ensuring ease of operation, further improves the sealing safety and long-term reliability of the device.

[0028] When in use, when the operator rotates to open the sealing cover 210, the guide rail 221 of the cleaning component 220 drives the cleaning brush 227 to move upward and separate from the siphon tube body 150. After sampling or placing the sample, during the closing process, the rotation of the sealing cover 210 is linked by the return spring 223 and the connecting piece 224, causing the cleaning brush 227 to spiral down along the outer wall of the siphon tube body 150, automatically scraping off the frost layer on the surface of the siphon tube body 150. The scraped frost is guided into the collection box 124 through the guide slot 123. At the same time, the locking component 240 fixes the sealing cover 210 through the cooperation of the locking rod 244 and the locking slot 245, ensuring that the sealing ring 230 and the heat preservation tank 130 form a reliable seal. The entire process can be completed without additional operation for cleaning and sealing.

[0029] In summary, the outer shell 110 of the supporting mechanism 100 and the heat preservation tank 130 form a stable low-temperature storage environment, which, together with the collection component 120, effectively handles condensate. The sealing mechanism 200 adopts a threaded sealing cap 210 and a self-cleaning cleaning component 220, which ensures sealing performance while realizing the automatic defrosting function of the siphon tube 150. The adaptive contact design between the cleaning brush 227 and the siphon tube 150, as well as the flow guiding structure of the collection component 120, solve the problem of frost accumulation in traditional devices.

[0030] It is important to note that the constructions and arrangements of this application shown in several different exemplary embodiments are merely illustrative. Although only a few embodiments are described in detail in this disclosure, those who consult this disclosure will readily understand that many modifications are possible (e.g., changes in the size, dimensions, structure, shape and proportion of various elements, as well as parameter values ​​(e.g., temperature, pressure, etc.), mounting arrangements, use of materials, color, orientation, etc.) without substantially departing from the novel teachings and advantages of the subject matter described in this application). For example, an element shown as integrally formed may be composed of multiple parts or elements, the position of elements may be inverted or otherwise altered, and the nature or number or position of discrete elements may be changed or altered. Therefore, all such modifications are intended to be included within the scope of this utility model. The order or sequence of any process or method steps may be changed or reordered according to alternative embodiments. In the claims, any "device plus function" clause is intended to cover the structure described herein that performs the function, and not only structural equivalents but also equivalent structures. Without departing from the scope of this invention, other substitutions, modifications, alterations, and omissions may be made in the design, operation, and arrangement of the exemplary embodiments. Therefore, this invention is not limited to the specific embodiments, but extends to various modifications that still fall within the scope of the appended claims.

[0031] Furthermore, in order to provide a concise description of exemplary embodiments, not all features of actual embodiments (i.e., those features that are not relevant to the best mode of carrying out the present invention as currently considered, or those features that are not relevant to implementing the present invention) may be omitted.

[0032] It should be understood that numerous specific implementation decisions can be made during the development of any practical implementation, such as in any engineering or design project. Such development efforts may be complex and time-consuming, but for those skilled in the art who benefit from this disclosure, the development effort will be a routine work of design, manufacturing, and production without requiring much experimentation.

[0033] It should be noted that the above embodiments are only used to illustrate the technical solution of this utility model and are not intended to limit it. Although this utility model has been described in detail with reference to preferred embodiments, those skilled in the art should understand that modifications or equivalent substitutions can be made to the technical solution of this utility model without departing from the spirit and scope of the technical solution of this utility model, and all such modifications or substitutions should be covered within the scope of the claims of this utility model.

Claims

1. A low-temperature constant-pressure sealing storage device for stem cell cryopreservation, characterized by: include, The support mechanism (100) includes a housing (110), a collection assembly (120) disposed at the bottom of the housing (110), and a heat preservation tank (130) fixedly installed in the inner cavity of the housing (110). The sealing mechanism (200) includes a sealing cap (210) threaded onto the top of the housing (110), a cleaning assembly (220) disposed at the bottom of the sealing cap (210), a sealing ring (230) fixedly mounted on the bottom of the sealing cap (210), and a locking assembly (240) disposed on the outside of the housing (110). The cleaning assembly (220) includes a guide rail (221) fixedly installed at the bottom of the sealing cover (210), a fixing block (222) fixedly installed in the inner cavity of the guide rail (221), a return spring (223) fixedly installed on the outside of the fixing block (222), and a connecting piece (224) fixedly installed at the end of the return spring (223).

2. The low-temperature constant-pressure sealing storage device for stem cell cryopreservation according to claim 1, characterized in that: The cleaning assembly (220) also includes a telescopic block (225) fixedly installed on the outside of the connecting piece (224), an arc-shaped piece (226) fixedly installed on the bottom of the telescopic block (225), and a cleaning brush (227) fixedly installed at a vertical angle on the outside of the arc-shaped piece (226).

3. The low-temperature constant-pressure sealing storage device for stem cell cryopreservation according to claim 2, characterized in that: The support mechanism (100) further includes a hollow chamber (140) formed in the inner cavity of the outer shell (110), and a siphon tube body (150) fixedly installed inside the hollow chamber (140).

4. The low-temperature constant-pressure sealing storage device for stem cell cryopreservation according to claim 3, characterized in that: The outer side of the cleaning brush (227) contacts the outer side of the siphon tube body (150) to remove frost and debris.

5. The low-temperature constant-pressure sealing storage device for stem cell cryopreservation according to claim 4, characterized in that: The collection assembly (120) includes a base (121) fixedly installed at the bottom of the housing (110), a water-blocking strip (122) fixedly installed in the inner cavity of the base (121), a guide slot (123) opened on the top of the water-blocking strip (122), and a collection box (124) fixedly installed at the bottom of the water-blocking strip (122).

6. The low-temperature constant-pressure sealing storage device for stem cell cryopreservation according to claim 5, characterized in that: The locking assembly (240) includes a bearing (241) fixedly mounted on the outside of the housing (110), a positioning sleeve (242) hinged to the outside of the bearing (241), and a limiting rod (243) fixedly mounted on the outside of the positioning sleeve (242).

7. The low-temperature constant-pressure sealing storage device for stem cell cryopreservation according to claim 6, characterized in that: The locking assembly (240) also includes a locking rod (244) fixedly installed on the outside of the housing (110) and a slot (245) opened at the bottom of the limiting rod (243). The locking rod (244) is movably locked in the inner cavity of the slot (245) to realize the positioning sleeve (242) being fixed after unfolding.