A cell separation filtration device

Abstract

The utility model relates to filter device technical field discloses a cell separation filter device, including separation filter drum, drive motor, device casing, wherein, separation filter drum rotation is connected in device casing inside, and with drive motor's output shaft linkage, drive motor is located separation filter drum top, and drive motor's output shaft is linked with separation filter drum between being equipped with the linkage structure for the linkage of both. Through above technical scheme, solved the prior art in drive motor below separation filter drum and led to the problem that the sealing element needed to be arranged between both, and the sealing element was easily damaged due to the dynamic seal between the output shaft of the drive motor, thereby causing the contamination of the cell liquid.

Description

Technical Field

[0001] This utility model relates to the field of filtration device technology, and in particular to a cell separation filtration device. Background Technology

[0002] Cell separation and filtration devices generally refer to laboratory tools that, based on the principle of physical sieving and the differences in cell size, rapidly separate, purify, or remove specific cell populations from mixed cell samples.

[0003] Currently, common cell separation and filtration devices typically include a filter cartridge and a drive motor to rotate the filter cartridge. In traditional filtration devices, to avoid the presence of the drive motor affecting the cell addition process, the drive motor is usually placed directly below the filter cartridge. This also means that the separated cell solution must pass through the output shaft of the drive motor before it can be discharged from the device.

[0004] Therefore, existing cell separation and filtration devices typically require a sealing assembly for the drive motor to ensure a tight seal between the motor and the separation chamber, thus preventing contamination of the cell solution or motor malfunction. However, due to the high-speed rotation of the drive motor's output shaft, the sealing assembly is a vulnerable component in the filtration device. This not only poses a higher risk of contamination to traditional cell separation and filtration devices but also complicates maintenance (requiring regular inspection of the sealing assembly to prevent damage from interfering with normal operation). Utility Model Content

[0005] The main purpose of this invention is to provide a cell separation and filtration device that solves the problem in related technologies where the drive motor is located below the separation and filtration cylinder, requiring a seal between the two, and the seal is easily damaged by the dynamic seal between it and the output shaft of the drive motor, thus causing cell fluid contamination.

[0006] To achieve the above objectives, the technical solution of this utility model is as follows:

[0007] A cell separation and filtration device includes a separation filter cylinder, a drive motor, and a device housing. The separation filter cylinder is rotatably connected inside the device housing and is linked with the output shaft of the drive motor. The drive motor is located above the separation filter cylinder, and a linkage structure for linking the two is provided between the output shaft of the drive motor and the separation filter cylinder.

[0008] Furthermore, the linkage structure includes a linkage gear and a drive gear. The linkage gear is a ring gear, and the inner ring of the linkage gear is fixedly connected to the separation filter cylinder. The drive gear is linked to the output shaft of the drive motor, and the drive gear and the linkage gear mesh with each other.

[0009] Furthermore, the device housing is provided with a partition ring, the separating filter cylinder is rotatably connected to the inner ring of the partition ring, and the linkage gear is located above the partition ring.

[0010] Furthermore, the device housing includes a cover and a cylinder, the cover and the cylinder being detachably connected, the cover having a feed inlet, the cylinder including a separation chamber and a mounting plate base, and the drive gear located in the mounting plate base.

[0011] Furthermore, the cover includes a first retaining ring and a second retaining ring, which are located inside and outside the separation cavity, respectively; the end of the first retaining ring close to the linkage gear abuts against the linkage gear.

[0012] Furthermore, the spacer ring is provided with a guide rail, and the linkage gear is provided with a mating groove for cooperating with the guide rail.

[0013] Furthermore, the linkage gear includes a connecting ring portion and a linkage tooth portion, the connecting ring portion being located between the separation filter cartridge and the linkage tooth portion, and the mating groove being formed on the connecting ring portion.

[0014] The working principle and beneficial effects of this utility model are as follows:

[0015] This utility model's technical solution addresses the issue of a series of problems caused by the failure of the sealing component due to wear by placing the drive motor above the separation filter cylinder. This is achieved by placing the drive motor above the separation filter cylinder, thus eliminating the need for a sealing component between the drive motor and the separation filter cylinder.

[0016] Furthermore, a linkage structure is provided between the output shaft of the drive motor and the separation filter cylinder for linkage between the two. The existence of the linkage structure allows the drive motor to drive the separation filter cylinder to rotate even when it does not need to be on the same axis as the separation filter cylinder, effectively preventing the drive motor from blocking the material feeding path and affecting the feeding operation. Attached Figure Description

[0017] To more clearly illustrate the technical solutions in the embodiments of this utility model or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on the structures shown in these drawings without creative effort.

[0018] Figure 1 This is a schematic diagram of the structure of this embodiment;

[0019] Figure 2 This is a schematic diagram of the structure without a drive motor in this embodiment;

[0020] Figure 3 This is a cross-sectional view of the embodiment without a drive motor;

[0021] Figure 4 This is a schematic diagram showing the interaction between each gear and the separation filter cylinder in this embodiment.

[0022] Explanation of icon numbers:

[0023] 1. Separating filter cartridge; 2. Drive motor; 3. Device housing; 31. Spacer ring; 311. Guide rail; 32. Cover; 321. First retaining ring; 322. Second retaining ring; 323. Feed inlet; 33. Cylinder body; 331. Separating chamber; 332. Mounting plate base; 4. Linkage structure; 41. Linkage gear; 411. Mating groove; 412. Connecting ring; 413. Linkage gear; 42. Drive gear.

[0024] The realization of the purpose, functional features and advantages of this utility model will be further explained in conjunction with the embodiments and with reference to the accompanying drawings. Detailed Implementation

[0025] To make the objectives, technical solutions, and advantages of this application clearer, the following detailed description is provided in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative and not intended to limit the scope of this application.

[0026] like Figures 1-3 As shown, this embodiment proposes a cell separation and filtration device, which mainly includes a separation filter cylinder 1, a drive motor 2, and a device housing 3. The separation filter cylinder 1 is rotatably connected inside the device housing 3 and is linked with the output shaft of the drive motor 2. The drive motor 2 is located above the separation filter cylinder 1. With this positional relationship, the drive motor 2 does not need to be in the cell fluid separation and filtration path, and therefore there is no need to set sealing components such as sealing rings between the output shaft of the drive motor 2 and the separation filter cylinder 1. This fundamentally solves a series of problems caused by the failure of sealing components due to wear (such as cell fluid contamination, motor damage, etc.).

[0027] Furthermore, a linkage structure 4 for linking the two is provided between the output shaft of the drive motor 2 and the separation filter cylinder 1. The existence of the linkage structure 4 allows the drive motor 2 to drive the separation filter cylinder 1 without having to be on the same axis as the separation filter cylinder 1, effectively preventing the drive motor 2 from blocking the feeding path and affecting the feeding work.

[0028] Specifically, such as Figures 3-4The linkage structure 4 shown mainly includes a linkage gear 41 and a drive gear 42. The linkage gear 41 is a ring gear, and the inner ring of the linkage gear 41 is fixedly connected to the separation filter cylinder 1. Preferably, the linkage gear 41 and the separation filter cylinder 1 are integrally formed to ensure the reliability and strength of the connection between the two. The drive gear 42 is linked to the output shaft of the drive motor 2, and the drive gear 42 and the linkage gear 41 mesh with each other. That is, this embodiment uses a gear transmission structure to link the output shaft of the drive motor 2 and the separation filter cylinder 1. Compared with traditional eccentric transmission structures such as belt drive structures, there is no structure between the linkage gear 41 and the drive gear 42 that can prevent the two from being separated. So that after the use of this embodiment, the user can directly take the separation filter cylinder 1 out of the device housing 3 to carry out the cleaning work.

[0029] To prevent cell fluid from splashing onto gears under the centrifugal force of the rotating separation filter cylinder 1, the device housing 3 is provided with a partition ring 31. The separation filter cylinder 1 is rotatably connected to the inner ring of the partition ring 31, and the linkage gear 41 is located above the partition ring 31. That is, the partition ring 31 isolates the cell fluid from each gear, effectively preventing cell fluid from being contaminated by contact with the gears.

[0030] Meanwhile, the spacer ring 31 is provided with a guide rail 311, which is connected end to end in a circular structure. The linkage gear 41 is provided with a mating groove 411 for cooperating with the guide rail 311. That is, by means of the cooperation between the guide rail 311 and the linkage gear 41, the running movement path and positional relationship of the linkage gear 41 are effectively constrained. This ensures that the separation filter cylinder 1 will not deviate, shake or jam during the movement, and the movement trajectory is very stable, ensuring the accuracy and consistency of the final action. The guide rail 311 is preferably integrally formed with the spacer ring 31 to ensure the connection strength between the two.

[0031] To prevent the opening of the mating groove 411 from damaging the tooth strength of the linkage gear 41 and thus increasing the risk of tooth breakage, the linkage gear 41 in this embodiment includes a connecting ring portion 412 and a linkage tooth portion 413. The connecting ring portion 412 is located between the separation filter cylinder 1 and the linkage tooth portion 413. The mating groove 411 is opened on the connecting ring portion 412, that is, there is a transition part between the tooth feature of the linkage gear 41 and the separation filter cylinder 1. The mating groove 411 is opened on the cover filter portion, which not only effectively reduces the fit of tooth breakage, but also further reduces the risk of cell fluid contacting the tooth feature by means of the mutual cooperation between the guide rail 311 and the mating groove 411.

[0032] The device housing 3 includes a cover 32 and a cylinder 33. A spacer ring 31 is disposed in the cylinder 33 and integrally formed with the cylinder 33 to ensure the connection strength between the two. The cover 32 and the cylinder 33 are detachably connected. Preferably, in this embodiment, the cover 32 and the cylinder 33 are connected by a threaded connection to achieve the detachable connection between the two, which ensures both the connection strength and the sealing performance between the two. The cover 32 has a feed inlet 323. Correspondingly, a feed hopper should be provided at the feed inlet 323 to facilitate the addition of cell fluid in this embodiment. The cylinder 33 includes a separation chamber 331 and a mounting plate 332. The drive gear 42 is located in the mounting plate 332. That is, the cylinder 33 has two relatively independent spaces, reducing the possibility of mutual interference between the objects in each space.

[0033] Correspondingly, the mounting plate 332 should be equipped with a motor mount for fixing the drive motor 2 to ensure that the drive motor 2 can stably provide driving force. The specific structure of the motor mount should be determined according to the actual type and model of the motor selected, which will not be described in detail in this embodiment.

[0034] Meanwhile, the cover 32 includes a first retaining ring 321 and a second retaining ring 322. The first retaining ring 321 and the second retaining ring 322 are located inside and outside the separation cavity 331, respectively, thus playing different roles. The second retaining ring 322 is equipped with threaded features for threaded connection with the cylinder 33. The end of the first retaining ring 321 close to the linkage gear 41 abuts against the linkage gear 41. That is, the first retaining ring 321, through contact with the linkage gear 41, prevents cell fluid from entering the tooth features of the linkage gear 41 when cell fluid is added, thereby preventing contamination.

[0035] Preferably, the first retaining ring 321 abuts against the connecting ring portion 412. If necessary, the inner ring diameter of the first retaining ring 321 is consistent with the inner diameter of the separation filter cartridge 1, thereby avoiding a step structure on the cell fluid addition path, thus avoiding dead corners of cell fluid residue inside this embodiment, reducing the risk of cross-contamination, improving sample recovery rate, and ensuring separation purity. Correspondingly, when there is a chamfer feature at the inlet of the separation filter cartridge 1, the inner ring diameter of the first retaining ring 321 is consistent with the outer diameter of the chamfer.

[0036] In the accompanying drawings of this embodiment, the same or similar reference numerals correspond to the same or similar components. In the description of this application, it should be understood that if terms such as "upper," "lower," "left," and "right" indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings, they are only for the convenience of describing this application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, the terms used to describe positional relationships in the accompanying drawings are only for illustrative purposes and should not be construed as limiting this patent. For those skilled in the art, the specific meaning of the above terms can be understood according to the specific circumstances.

[0037] The above are merely preferred embodiments of this application and are not intended to limit this application. Any modifications, equivalent substitutions, and improvements made within the spirit and principles of this application should be included within the protection scope of this application.

Claims

1. A cell separation and filtration device, comprising a separation filter cylinder (1), a drive motor (2), and a device housing (3), wherein the separation filter cylinder (1) is rotatably connected inside the device housing (3) and is linked with the output shaft of the drive motor (2), characterized in that, The drive motor (2) is located above the separation filter cylinder (1), and a linkage structure (4) for linking the two is provided between the output shaft of the drive motor (2) and the separation filter cylinder (1).

2. The cell separation filtration device of claim 1, wherein, The linkage structure (4) includes a linkage gear (41) and a drive gear (42). The linkage gear (41) is a ring gear, and the inner ring of the linkage gear (41) is fixedly connected to the separation filter cylinder (1). The drive gear (42) is linked to the output shaft of the drive motor (2), and the drive gear (42) meshes with the linkage gear (41).

3. The cell separation filtration device of claim 2, wherein, The housing (3) of the device is provided with a partition ring (31), the separation filter cylinder (1) is rotatably connected to the inner ring of the partition ring (31), and the linkage gear (41) is located above the partition ring (31).

4. The cell separation and filtration device according to claim 2, characterized in that, The device housing (3) includes a cover (32) and a cylinder (33). The cover (32) and the cylinder (33) are detachably connected. The cover (32) has a feed inlet (323). The cylinder (33) includes a separation chamber (331) and a mounting plate (332). The drive gear (42) is located in the mounting plate (332).

5. The cell separation filtration device of claim 4, wherein, The cover (32) includes a first retaining ring (321) and a second retaining ring (322), the first retaining ring (321) and the second retaining ring (322) being located inside and outside the separation cavity (331), respectively; The end of the first retaining ring (321) close to the linkage gear (41) abuts against the linkage gear (41).

6. The cell separation filtration device of claim 3, wherein, The spacer ring (31) is provided with a guide rail (311), and the linkage gear (41) is provided with a mating groove (411) for cooperating with the guide rail (311).

7. The cell separation and filtration device according to claim 6, characterized in that, The linkage gear (41) includes a connecting ring (412) and a linkage tooth (413). The connecting ring (412) is located between the separation filter cylinder (1) and the linkage tooth (413). The mating groove (411) is formed on the connecting ring (412).

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