A sampling device for virus infected cells

Abstract

The utility model relates to a sampling device for virus infection cell belongs to virus cell sampling technical field, the sampling device for virus infection cell, include: storage bin, one side of storage bin is provided with sampling pipe, sampling protection mechanism is used for the protection of virus infection cell sampling and sets up in one side of storage bin sampling protection mechanism, wherein, sampling protection mechanism includes the connecting pipe fixed mounting between sampling pipe and storage bin, the inside of storage bin is provided with sampling assembly, the inside of storage bin still is provided with placement assembly, sampling protection mechanism can form closed environment in the whole sampling process, prevents virus-containing sample and air contact and reduces aerosol diffusion. The connecting pipe realizes sample solution airtight transmission, avoids the pollution of outside leakage, sampling assembly automatically disinfects the inner wall of storage bin after sampling, keeps aseptic safety, the placement assembly is used for fixing petri dish or sample carrier, ensures that sampling needle positioning is accurate, and the operation is stable.

Description

Technical Field

[0001] This utility model relates to the field of virus cell sampling technology, and in particular to a sampling device for virus-infected cells. Background Technology

[0002] In the process of culturing and studying virus-infected cells, researchers often need to extract a certain amount of cell fluid or culture medium from infected samples for detection and analysis. Because the samples contain high concentrations of active virus particles, aerosol diffusion is highly likely if the sampling process is exposed to air, leading to environmental contamination and the risk of infection for personnel. Therefore, the sampling of virus-infected cells is usually required to be carried out under closed, leak-proof conditions to ensure experimental safety and sample purity.

[0003] Existing virus sample collection devices typically employ a single-layer sealed rubber plug or a pluggable interface structure. Because such sealing structures are prone to deformation or wear during repeated punctures or insertions, and because traditional sampling interfaces require manual external wiping or alcohol spraying for disinfection after use, the limited disinfection range and difficulty in covering the entire channel surface easily lead to localized residues, thus creating a risk of cross-contamination. Utility Model Content

[0004] Therefore, it is necessary to address the issue that existing virus sample collection devices often employ single-layer sealed rubber plugs or pluggable interface structures, which are prone to deformation and wear after repeated use. Furthermore, manual wiping or alcohol spraying has a limited range of disinfection, making it difficult to completely remove residues and easily leading to cross-contamination. In this regard, a sampling device for virus-infected cells should be provided.

[0005] A sampling device for virus-infected cells includes: a storage chamber, on one side of which a sampling tube is disposed; and a sampling protection mechanism disposed on one side of the storage chamber for protecting the virus-infected cell sampling. The sampling protection mechanism includes a connecting pipe fixedly installed between the sampling tube and the storage chamber. The storage chamber contains a sampling component and a placement component.

[0006] The sampling assembly includes a protective tube fixedly installed on the top of the storage compartment. One side of the protective tube extends to the top of the assembly. One side of the connecting tube is connected to the protective tube. Two sealing diaphragms are fixedly installed inside the protective tube, and the two sealing diaphragms are staggered.

[0007] Two sterilizers are fixedly installed on the outside of the protective tube, and both sterilizers are designed in an arc shape.

[0008] The disinfection device has multiple lamps fixedly installed on the side near the protective tube, and the multiple lamps are distributed at equal intervals.

[0009] A sealing ring is fixedly installed on the outer side of the connecting pipe, the sealing ring is located on the inner wall of the protective pipe, and a telescopic pipe is fixedly installed on the surface of the connecting pipe.

[0010] A one-way suction tube is fixedly installed at the top of the sampling tube, and one end of the one-way suction tube extends into the interior of the sampling tube.

[0011] The placement assembly includes a sealing frame that is slidably mounted on one side of the storage compartment, and a placement plate is fixedly installed inside the sealing frame, with the placement plate located at the bottom of one end of the connecting pipe.

[0012] The surface of the placement plate is provided with a positioning groove, which is configured in the shape of a funnel.

[0013] Beneficial effects 1. The sampling protection mechanism creates a closed environment throughout the sampling process, preventing virus-containing samples from coming into contact with the air and reducing aerosol diffusion. The connecting tube ensures sealed sample transfer, preventing leakage and contamination; the sampling components automatically disinfect the inner wall of the storage chamber after sampling, maintaining sterility and safety; the placement components are used to fix culture dishes or sample carriers, ensuring accurate positioning of the sampling needle and stable operation. 2. The placement plate is located at the bottom of one end of the connecting tube and can serve as a support base for the sample. During the sampling process, it provides stable support for the culture dish or cell carrier being sampled, preventing the sample from shaking or tilting due to the insertion force of the sampling needle or liquid aspiration. The sealing frame and the inner wall of the storage chamber have a sliding sealing connection structure, which can be moved smoothly along the guide rail when the position of the culture dish needs to be changed or adjusted. This facilitates the alignment of the sampling point without damaging the sealing state of the storage chamber. Attached Figure Description

[0014] To more clearly illustrate the technical solutions in this utility model or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of this utility model. For those skilled in the art, other drawings can be obtained from these drawings without creative effort.

[0015] Figure 1 This is a schematic diagram of the main structure of this utility model; Figure 2 This is a schematic diagram of the sampling protection mechanism of this utility model; Figure 3 This is a schematic diagram of the internal structure of the storage compartment of this utility model; Figure 4 This is a schematic diagram of the internal structure of the sampling tube of this utility model; Figure 5 This is a schematic diagram of the placement component structure of this utility model.

[0016] Figure label: 100. Storage compartment; 200. Sampling tube; 300. Sampling protection mechanism; 310. Connecting tube; 320. Sampling assembly; 321. Protective tube; 322. Sealing diaphragm; 323. Sterilizer; 324. Lamp tube; 325. Sealing ring; 326. Telescopic tube; 327. One-way exhaust tube; 330. Placement assembly; 331. Sealing frame; 332. Placement plate; 333. Positioning groove. Detailed Implementation

[0017] To make the objectives, technical solutions, and advantages of the embodiments of this utility model clearer, the technical solutions of the embodiments of this utility model will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some, not all, of the embodiments of this utility model. All other embodiments obtained by those skilled in the art based on the embodiments of this utility model without creative effort are within the scope of protection of this utility model.

[0018] The following is combined with Figures 1-5 This invention describes a sampling device for virus-infected cells.

[0019] In one embodiment, a sampling device for virus-infected cells includes: a storage chamber 100, with a sampling tube 200 disposed on one side of the storage chamber 100; and a sampling protection mechanism 300 disposed on one side of the storage chamber 100 for protecting the virus-infected cell sampling. The sampling protection mechanism 300 includes a connecting pipe 310 fixedly installed between the sampling tube 200 and the storage chamber 100, and a sampling component 320 and a placement component 330 are disposed inside the storage chamber 100.

[0020] In this embodiment, by setting up a sampling protection mechanism 300, a closed operating environment can be formed throughout the sampling process, effectively preventing virus-containing samples from directly contacting the outside air and reducing the risk of aerosol diffusion. The connecting tube 310 connects the sampling tube 200 and the storage chamber 100, enabling sealed transmission of the sample liquid within the sampling channel to prevent leakage and contamination. The sampling component 320 is located inside the storage chamber 100 and can automatically initiate a disinfection program after sampling to rapidly sterilize the inner wall of the storage chamber 100 and the sampling area, ensuring the sterility and safety of the secondary sampling environment. The placement component 330 can position and fix the culture dish or sample carrier, allowing the sampling needle to accurately align with the target area, improving operational stability and sampling accuracy. It should be noted that existing virus-infected cell sampling devices typically include a storage chamber 100, a sampling tube 200, a sealing interface, a sample collection container, and a protective shell. The sampling component 320 is located inside the storage chamber 100. Its compact structure does not interfere with the installation of the original sampling tube 200 or the liquid flow channel. Furthermore, its sterilization function is only activated after sampling is completed, without affecting normal sampling operations. The placement component 330 is fixed to the bottom or side wall of the storage chamber 100 to support the culture dish or sample carrier. Its position avoids the sampling channel and fluid path, and does not change the movement trajectory of the sampling needle or liquid aspiration device. Therefore, it will not affect the sealing performance and sampling accuracy of the device.

[0021] like Figure 2 , Figure 3 and Figure 4 As shown, the sampling component 320 includes a protective tube 321 fixedly installed on the top of the storage compartment 100. One side of the protective tube 321 extends to the top of the placement component 330. One side of the connecting tube 310 is connected to the protective tube 321. Two sealing diaphragms 322 are fixedly installed inside the protective tube 321, and the two sealing diaphragms 322 are arranged alternately.

[0022] In this embodiment, by setting two staggered sealing diaphragms 322 inside the protective tube 321, the sampling channel forms a double-layered partition structure when not in use. This effectively blocks direct communication between the inside of the storage chamber 100 and the outside air, preventing the escape of viral aerosols. When the sampling needle or sampling tube 200 is inserted into the protective tube 321, the two sealing diaphragms 322 are sequentially opened to form a temporary sampling channel. After sampling, the diaphragms automatically reset and close under their own elasticity, quickly restoring the sealed state. Automatic sealing can be achieved without additional operation. Because the two sealing diaphragms 322 are staggered, the sampling needle will not form a through-line leakage path when passing through, thereby further improving airtightness and seepage prevention performance. This structure not only ensures smooth sampling operation but also immediately blocks air exchange after the sampling needle is removed, reducing the risk of virus spread.

[0023] Two sterilizers 323 are fixedly installed on the outside of the protective tube 321, and both sterilizers 323 are designed to be arc-shaped.

[0024] In this embodiment, two arc-shaped sterilizers 323 are fixedly installed on the outside of the protective tube 321, enabling them to fully cover the outer surface and surrounding area of ​​the protective tube 321. After sampling, the sterilizers 323 can be automatically activated to simultaneously irradiate and disinfect the outer wall of the protective tube 321 and the sampling channel interface, forming a UV sterilization area without dead angles. This effectively kills virus particles and microbial residues attached to the surface or interface edge of the protective tube 321. The arc-shaped structure of the sterilizers 323 can fit the shape of the protective tube 321, ensuring uniform UV irradiation distance and avoiding blind spots in local disinfection caused by deviations in the light angle. It should be noted that the protective tube 321 is made of a transparent material with high light transmittance and corrosion resistance, preferably medical-grade polycarbonate or high borosilicate glass. This material has excellent light transmittance, which can effectively improve the transmittance of ultraviolet light. When the sterilizer 323 is located outside the protective tube 321, its ultraviolet irradiation energy can fully act on the inner surface of the protective tube 321 and the sealing diaphragm 322 area, thereby achieving simultaneous sterilization of the internal channel. At the same time, the surface of the material of the protective tube 321 is treated with anti-adhesion or adopts a smooth and dense structure design, which can reduce the adhesion of virus particles, cell debris and culture medium residues, prevent contaminants from accumulating on the tube wall and forming dead corners, improve the cleanliness and reusability of the internal environment. The protective tube 321 has high mechanical strength and chemical resistance, and can withstand ultraviolet irradiation, alcohol or disinfectant spraying for a long time without deformation, cracking or light transmittance attenuation, ensuring that the device maintains stable performance and good sealing effect during multiple sampling and sterilization cycles.

[0025] Multiple lamps 324 are fixedly installed on the side of the sterilizer 323 near the protective tube 321, and the multiple lamps 324 are distributed at equal intervals.

[0026] In this embodiment, by fixing multiple lamps 324 on the side of each sterilizer 323 near the protective tube 321 and distributing the multiple lamps 324 at equal intervals, a uniformly covered ultraviolet irradiation area can be formed on the entire outer periphery of the protective tube 321. When working, the lamps 324 generate high-intensity ultraviolet radiation, ensuring that the irradiation energy is evenly distributed on the outer wall and internal channel surface of the protective tube 321, avoiding localized insufficient irradiation or shadowed areas, thereby achieving highly efficient sterilization of the entire area of ​​the protective tube 321. It should be noted that the sterilizer 323 is an integrated ultraviolet sterilization component, mainly used for efficient sterilization of the outer surface and internal channels of the protective tube 321 after sampling. The sterilizer 323 preferably uses a short-wave UVC band ultraviolet light source, which has a strong bactericidal effect and can rapidly inactivate viruses and bacteria by destroying their molecular structure.

[0027] A sealing ring 325 is fixedly installed on the outside of the connecting pipe 310. The sealing ring 325 is located on the inner wall of the protective pipe 321. A telescopic pipe 326 is fixedly installed on the surface of the connecting pipe 310.

[0028] In this embodiment, when the sampling tube 200 is inserted into the protective tube 321 for sampling, the telescopic tube 326 can automatically extend or retract according to the insertion depth to adjust the connection length and avoid stress concentration or separation at the interface due to rigid fixation. The sealing ring 325 fits snugly against the inner wall of the protective tube 321 and can maintain an airtight state during the movement of the telescopic tube 326.

[0029] A one-way suction pipe 327 is fixedly installed on the top of the sampling tube 200, and one end of the one-way suction pipe 327 extends into the interior of the sampling tube 200.

[0030] In this embodiment, the one-way suction tube 327 can form a stable negative pressure suction channel during sampling. When the one-way suction tube 327 starts suction, the negative pressure generated inside it will be transmitted along the sampling tube 200 to the connecting tube 310, so that a continuous negative pressure environment is formed in the sampling channel, thereby drawing the sample liquid or cell culture medium in the storage chamber 100 into the sampling tube 200.

[0031] like Figure 2 , Figure 3 and Figure 5 As shown, the placement assembly 330 includes a sealing frame 331 that is slidably mounted on one side of the storage compartment 100. A placement plate 332 is fixedly mounted inside the sealing frame 331. The placement plate 332 is located at the bottom of one end of the connecting pipe 310.

[0032] In this embodiment, the placement plate 332 is located at the bottom of one end of the connecting tube 310 and can serve as a support base for the sample. During the sampling process, it provides stable support for the culture dish or cell carrier being sampled, preventing the sample from shaking or tilting due to the insertion force of the sampling needle or liquid aspiration. The sealing frame 331 and the inner wall of the storage chamber 100 are connected by a sliding seal structure, which can move smoothly along the guide rail when the position of the culture dish needs to be replaced or adjusted. This facilitates the alignment of the sampling point without damaging the sealing state of the storage chamber 100.

[0033] The surface of the placement plate 332 is provided with a positioning groove 333, which is shaped like a funnel.

[0034] In this embodiment, by creating a funnel-shaped positioning groove 333 on the surface of the placement plate 332, automatic centering positioning can be achieved when placing the culture dish or sample carrier. The inclined inner wall of the funnel-shaped structure can guide the culture dish to slide towards the center position during placement, so that its bottom falls stably into the bottom of the groove, preventing errors in needle insertion angle or inconsistent liquid level due to deviation during sampling operations.

[0035] Working principle: The culture dish or cell sample is placed in the positioning groove 333 of the placement plate 332. The funnel-shaped structure of the positioning groove 333 automatically guides the sample to be centered, ensuring accurate alignment of the sampling needle with the target area. Subsequently, the sampling tube 200 is connected to the storage chamber 100 through the connecting tube 310. The one-way suction tube 327 is activated to create negative pressure, causing the sample liquid to be drawn into the sampling tube 200 along the sealed channel, achieving safe sampling. During the sampling process, the sampling needle passes through two layers of sealing diaphragms 322 staggered inside the protective tube 321, forming a temporary channel to complete the suction operation. After sampling, the sealing diaphragms 322 automatically close under elastic action, restoring the seal and preventing the leakage of aerosols or virus particles. At the same time, the sterilizer 323 set on the outside of the protective tube 321 is automatically activated. Multiple equidistant lamps 324 emit ultraviolet light to irradiate and sterilize the outer wall and internal channel of the protective tube 321 from all directions, eliminating residual virus or cell contamination. The entire sampling process is completed in a closed environment, with the connecting tube 310 and the telescopic tube 326 maintaining an airtight fit to ensure that no leakage occurs during the entire process of operation, suction, and disinfection.

[0036] The above embodiments are only used to illustrate the technical solutions of this utility model, and are not intended to limit it. Although this utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some of the technical features. Such modifications or substitutions will not cause the essence of the corresponding technical solutions to deviate from the spirit and scope of the technical solutions of the embodiments of this utility model.

Claims

1. A sampling device for virus-infected cells, characterized in that, include: A storage compartment (100) is provided with a sampling tube (200) on one side of the storage compartment (100). A sampling protection mechanism (300) for protecting virus-infected cell sampling is disposed on one side of the storage compartment (100); The sampling protection mechanism (300) includes a connecting pipe (310) fixedly installed between the sampling tube (200) and the storage chamber (100). The storage chamber (100) is equipped with a sampling component (320) and a placement component (330).

2. The sampling device for virus-infected cells according to claim 1, characterized in that, The sampling assembly (320) includes a protective tube (321) fixedly installed on the top of the storage compartment (100). One side of the protective tube (321) extends to the top of the placement assembly (330). One side of the connecting tube (310) is connected to the protective tube (321). Two sealing diaphragms (322) are fixedly installed inside the protective tube (321), and the two sealing diaphragms (322) are staggered.

3. The sampling device for virus-infected cells according to claim 2, characterized in that, Two sterilizers (323) are fixedly installed on the outside of the protective tube (321), and both sterilizers (323) are set in an arc shape.

4. The sampling device for virus-infected cells according to claim 3, characterized in that, The disinfection device (323) has multiple lamps (324) fixedly installed on the side near the protective tube (321), and the multiple lamps (324) are all equidistantly distributed.

5. The sampling device for virus-infected cells according to claim 4, characterized in that, A sealing ring (325) is fixedly installed on the outside of the connecting pipe (310), the sealing ring (325) is located on the inner wall of the protective pipe (321), and a telescopic pipe (326) is fixedly installed on the surface of the connecting pipe (310).

6. The sampling device for virus-infected cells according to claim 1, characterized in that, A one-way suction pipe (327) is fixedly installed on the top of the sampling tube (200), and one end of the one-way suction pipe (327) extends into the interior of the sampling tube (200).

7. The sampling device for virus-infected cells according to claim 1, characterized in that, The placement assembly (330) includes a sealing frame (331) that is slidably mounted on one side of the storage compartment (100), and a placement plate (332) is fixedly mounted inside the sealing frame (331). The placement plate (332) is located at the bottom of one end of the connecting pipe (310).

8. The sampling device for virus-infected cells according to claim 7, characterized in that, The surface of the placement plate (332) is provided with a positioning groove (333), which is configured as a funnel shape.

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