An umbilical cord mesenchymal stem cell separation device

Abstract

The utility model relates to the extraction field especially a kind of umbilical cord mesenchymal stem cell separation device, including metal cylinder, support column is welded in the bottom inner wall center of metal cylinder, and the bottom inner wall of metal cylinder is welded with the support block of equidistance distribution, the inner wall sliding connection of metal cylinder has intercepting cylinder, and intercepting cylinder is welded with sliding tube at support column, the top outer wall of support column is equipped with crushing structure;Crushing structure includes transmission hole being opened in the center of metal cylinder and support column, is installed in the outer wall of the top end of support column flat bearing, rotationally connected in the inner wall of transmission hole transmission shaft and rotationally connected in the outer wall of flat bearing containing cylinder.The utility model metal cylinder is rotatably connected in support base by support shaft, when discharging is inconvenient, metal cylinder is overturned on support base by handle, metal cylinder is inclined, liquid is discharged from drain pipe, and auxiliary drainage is facilitated.

Description

Technical Field

[0001] This utility model relates to the field of extraction technology, and in particular to a device for separating umbilical cord mesenchymal stem cells. Background Technology

[0002] Umbilical cord mesenchymal stem cells (UC-MSCs) are a type of pluripotent stem cell found in the umbilical cord tissue of newborns. They can differentiate into many different types of tissue cells and have broad clinical application prospects. They are primarily derived from Wharton's jelly and perivascular tissue of the newborn's umbilical cord. After full-term pregnancy, fresh umbilical cord cells can be processed and expanded using explant methods or enzymatic digestion. Currently, the extraction of umbilical cord mesenchymal stem cells requires cleaning the fresh and healthy umbilical cord and thoroughly cutting the obtained tissue. However, the current tissue cutting efficiency is slow, and the cut tissue is relatively large, which affects the subsequent extraction. Utility Model Content

[0003] The purpose of this invention is to address the aforementioned problems and shortcomings by proposing a device for separating umbilical cord mesenchymal stem cells.

[0004] To achieve the above objectives, the present invention adopts the following technical solution: A device for separating umbilical cord mesenchymal stem cells includes a metal cylinder, a support column welded to the center of the bottom inner wall of the metal cylinder, and support blocks evenly distributed at intervals welded to the bottom inner wall of the metal cylinder. An intercepting cylinder is slidably connected to the inner wall of the metal cylinder, and a sliding tube is welded to the intercepting cylinder at the support column. A crushing structure is provided on the top outer wall of the support column. The crushing structure includes a transmission hole opened at the center of the metal cylinder and the support column, a plane bearing installed on the top outer wall of the support column, a transmission shaft rotatably connected to the inner wall of the transmission hole, and a receiving cylinder rotatably connected to the outer wall of the plane bearing.

[0005] Preferably, a drive block is welded to the center of the top outer wall of the drive shaft, and a drive groove adapted to the drive block is opened on the bottom outer wall of the receiving cylinder. A drive motor is installed on the bottom outer wall of the metal cylinder, and the output shaft of the drive motor is connected to one end of the drive shaft.

[0006] Preferably, the bottom outer wall of the intercepting cylinder is placed on the top outer wall of the support block, and the bottom outer wall of the intercepting cylinder has equally spaced intercepting holes. The top of the outer wall of the intercepting cylinder is welded with a positioning protrusion, and the metal cylinder has a sliding groove at the positioning protrusion.

[0007] Preferably, the inner wall of the intercepting cylinder is equipped with friction blocks that are evenly distributed at the center of the receiving cylinder, and the outer wall of the receiving cylinder is provided with friction holes that are evenly distributed.

[0008] Preferably, a top cover is installed on the outer wall of the top of the metal cylinder, and a cover-in-cover is installed on the top cover at the receiving cylinder. A drain pipe is provided at the bottom of one side of the outer wall of the metal cylinder, and the intercepting cylinder and the outer wall of the sliding pipe are slidably connected to the outer wall of the support column.

[0009] Preferably, a support shaft is welded to the top of the outer walls on both sides of the metal cylinder, and a support seat is rotatably connected to the outer wall of the support shaft. Handles are welded to the outer wall of the metal cylinder, the outer wall of the top cover, and the outer wall of the inner cover.

[0010] Preferably, the drive motor is connected to the switch via a wire, and the switch is connected to the power supply via a wire.

[0011] The beneficial effects of this utility model are as follows: The metal cylinder is rotatably connected to the support base via a support shaft. When it is inconvenient to discharge, the metal cylinder can be flipped on the support base by the handle to tilt the metal cylinder, so that the liquid can be discharged from the drain pipe and facilitate drainage. The friction blocks on the interceptor cylinder are replaced with friction blocks spaced at different distances from the receiving cylinder, depending on the required size to be ground, to facilitate the crushing of tissues. Attached Figure Description

[0012] Figure 1 This is a schematic diagram of the overall structure of an umbilical cord mesenchymal stem cell separation device proposed in this utility model. Figure 2 This is a schematic diagram of the unfolded structure of the metal cylinder of the umbilical cord mesenchymal stem cell separation device proposed in this utility model; Figure 3 This is a cross-sectional structural diagram of an umbilical cord mesenchymal stem cell separation device proposed in this utility model; Figure 4 This is a cross-sectional unfolded structural diagram of an umbilical cord mesenchymal stem cell separation device proposed in this utility model.

[0013] In the diagram: 1 Metal cylinder, 2 Support column, 3 Transmission hole, 4 Interception cylinder, 5 Sliding tube, 6 Positioning protrusion, 7 Crushing structure, 8 Friction block, 9 Interception hole, 10 Transmission shaft, 11 Drive block, 12 Planar bearing, 13 Receiving cylinder, 14 Friction hole, 15 Drive motor, 16 Support block, 17 Drain pipe, 18 Top cover, 19 Inner cover, 20 Handle, 21 Support base. Detailed Implementation

[0014] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present utility model. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Example

[0015] Reference Figure 1-4As shown, an umbilical cord mesenchymal stem cell separation device includes a metal cylinder 1, a support column 2 welded at the center of the bottom inner wall of the metal cylinder 1, and support blocks 16 evenly distributed at intervals welded to the bottom inner wall of the metal cylinder 1. An intercepting cylinder 4 is slidably connected to the inner wall of the metal cylinder 1, and a sliding tube 5 is welded to the intercepting cylinder 4 at the support column 2. A crushing structure 7 is provided on the top outer wall of the support column 2. The bottom outer wall of the intercepting cylinder 4 is placed on the top outer wall of the support block 16, and the bottom outer wall of the intercepting cylinder 4 is provided with equally spaced intercepting holes 9. The top of the outer wall of the intercepting cylinder 4 is welded with a positioning protrusion 6, and the metal cylinder 1 is provided with a sliding groove at the positioning protrusion 6. The inner wall of the intercepting cylinder 4 is equipped with friction blocks 8 that are evenly distributed at the center of the receiving cylinder 13, and the outer wall of the receiving cylinder 13 is provided with friction holes 14 that are evenly distributed. The friction blocks 8 on the intercepting cylinder 4 are replaced with friction blocks 8 at different distances from the receiving cylinder 13 according to the required size to be ground, so as to facilitate the crushing of tissues; The drive block 11 on the drive shaft 10 is inserted into the bottom center of the receiving cylinder 13 to facilitate the rotation of the receiving cylinder 13. The centrifugal force is used to throw the tissue out of the interception hole 9. The friction block 8 is used to crush the tissue and facilitate subsequent extraction. The interceptor cylinder 4 is placed on the support block 16 inside the metal cylinder 1 via the positioning protrusion 6, which facilitates positioning and installation. Example

[0016] Reference Figure 1-4 As shown, the crushing structure 7 includes a transmission hole 3 opened at the center of the metal cylinder 1 and the support column 2, a plane bearing 12 installed on the outer wall of the top of the support column 2, a transmission shaft 10 rotatably connected to the inner wall of the transmission hole 3, and a receiving cylinder 13 rotatably connected to the outer wall of the plane bearing 12. A drive block 11 is welded to the center of the top outer wall of the drive shaft 10, and a drive groove adapted to the drive block 11 is opened on the bottom outer wall of the receiving cylinder 13. A drive motor 15 is installed on the bottom outer wall of the metal cylinder 1, and the output shaft of the drive motor 15 is connected to one end of the drive shaft 10. The metal cylinder 1 is equipped with a top cover 18 on its top outer wall, and a cover-in-cover 19 is installed on the top cover 18 at the receiving cylinder 13. A drain pipe 17 is provided at the bottom of one side of the outer wall of the metal cylinder 1, and the intercepting cylinder 4 and the outer wall of the sliding pipe 5 are slidably connected to the outer wall of the support column 2. Support shafts are welded to the top of the outer walls on both sides of the metal cylinder 1, and support seats 21 are rotatably connected to the outer walls of the support shafts. Handles 20 are welded to the outer walls of the metal cylinder 1, the outer walls of the top cover 18, and the outer walls of the cover-in-cover 19. The drive motor 15 is connected to the switch via a wire, and the switch is connected to the power supply via a wire; The metal cylinder 1 is rotatably connected to the support base 21 via a support shaft. When it is inconvenient to discharge, the metal cylinder 1 can be flipped on the support base 21 by the handle 20, so that the metal cylinder 1 can be tilted to facilitate the discharge of liquid from the drain pipe 17, which facilitates auxiliary drainage. When finished using the product, first remove the top cover 18 and the inner cover 19, then lift the receiving cylinder 13 to remove it, and then lift the intercepting cylinder 4 from the inner wall of the metal cylinder 1 to remove the parts and facilitate subsequent cleaning, thus avoiding cleaning dead corners.

[0017] Working principle: In use, the cleaned tissue is placed on the inner wall of the container 13. The top cover 18 and the inner cover 19 are installed on the metal cylinder 1. The inner cover 19 blocks the top of the container 13. The drive motor 15 is started and drives the container 13 to rotate through the drive block 11 on the transmission shaft 10. Under the action of centrifugal force, the tissue inside the container 13 extends out to the outer wall of the container 13 through the friction hole. One end of the friction block 8 is close to the outer wall of the container 13. The tissue extending out from the friction hole 14 is crushed into the required size under the friction of the friction block 8. The tissue and tissue fluid are thrown into the interception cylinder 4 under the influence of centrifugal force. The separated tissue fluid then falls into the metal cylinder 1 through the interception hole 9 at the bottom of the interception cylinder 4. The extracted tissue fluid is then discharged from the drain pipe 17 for collection, which facilitates the crushing of tissue, the collection of tissue fluid, and subsequent extraction.

[0018] The exemplary embodiments of the present invention have been described in detail herein with reference to examples. However, those skilled in the art will understand that various modifications and alterations can be made to the specific embodiments described above without departing from the spirit of the present invention, and various combinations can be made to the various technical features and structures proposed in the present invention without exceeding the protection scope of the present invention, which is determined by the appended claims. The foregoing description of specific exemplary embodiments of the present invention is not intended to limit the present invention to the precise forms disclosed, and it is obvious that many changes and variations can be made based on the above teachings. The exemplary embodiments were chosen and described in order to explain the specific principles of the present invention and its practical applications, thereby enabling those skilled in the art to implement and utilize various different exemplary embodiments of the present invention, as well as various different choices and variations. The scope of the present invention is intended to be defined by the claims and their equivalents.

Claims

1. A device for isolating umbilical cord mesenchymal stem cells, comprising a metal cylinder (1), characterized in that, A support column (2) is welded to the center of the bottom inner wall of the metal cylinder (1), and support blocks (16) are welded to the bottom inner wall of the metal cylinder (1) at equal intervals. An interceptor cylinder (4) is slidably connected to the inner wall of the metal cylinder (1), and a sliding tube (5) is welded to the interceptor cylinder (4) at the support column (2). A crushing structure (7) is provided on the top outer wall of the support column (2). The crushing structure (7) includes a transmission hole (3) opened at the center of the metal cylinder (1) and the support column (2), a flat bearing (12) installed on the outer wall of the top of the support column (2), a transmission shaft (10) rotatably connected to the inner wall of the transmission hole (3), and a receiving cylinder (13) rotatably connected to the outer wall of the flat bearing (12).

2. The umbilical cord mesenchymal stem cell separation device according to claim 1, wherein, A drive block (11) is welded to the center of the outer wall of the top of the drive shaft (10), and a drive groove adapted to the drive block (11) is opened on the outer wall of the bottom of the receiving cylinder (13). A drive motor (15) is installed on the outer wall of the bottom of the metal cylinder (1), and the output shaft of the drive motor (15) is connected to one end of the drive shaft (10).

3. The umbilical cord mesenchymal stem cell separation device according to claim 1, wherein, The bottom outer wall of the intercepting cylinder (4) is placed on the top outer wall of the support block (16), and the bottom outer wall of the intercepting cylinder (4) is provided with equally spaced intercepting holes (9). The top of the outer wall of the intercepting cylinder (4) is welded with a positioning protrusion (6), and the metal cylinder (1) is provided with a sliding groove at the positioning protrusion (6).

4. The umbilical cord mesenchymal stem cell separation device according to claim 1, wherein, The inner wall of the interceptor tube (4) is equipped with friction blocks (8) that are evenly distributed at the center of the receiving tube (13), and the outer wall of the receiving tube (13) is provided with friction holes (14) that are evenly distributed.

5. The umbilical cord mesenchymal stem cell separation device according to claim 1, wherein, The metal cylinder (1) has a top cover (18) installed on its top outer wall, and the top cover (18) has a cover-in-cover (19) installed at the receiving cylinder (13). A drain pipe (17) is provided at the bottom of one side of the outer wall of the metal cylinder (1), and the intercepting cylinder (4) and the outer wall of the sliding pipe (5) are slidably connected to the outer wall of the support column (2).

6. The umbilical cord mesenchymal stem cell separation device according to claim 1, wherein, Support shafts are welded to the top of the outer walls on both sides of the metal cylinder (1), and support seats (21) are rotatably connected to the outer walls of the support shafts. Handles (20) are welded to the outer walls of the metal cylinder (1), the outer walls of the top cover (18), and the outer walls of the cover-in-cover (19).

7. The umbilical cord mesenchymal stem cell separation device according to claim 2, wherein, The drive motor (15) is connected to the switch via a wire, and the switch is connected to the power supply via a wire.

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