Detection cartridge

Abstract

The utility model provides a kind of detection card box.The detection card box includes: card box main body, card box main body has multiple reaction cavities and at least one sample adding bin, sample adding bin is communicated with reaction cavity;Sealing cover, sealing cover is set on card box main body with open and close, when sealing cover is pressed to card box main body, the liquid to be measured can enter reaction cavity by sample adding bin;Semi-permeable membrane, card box main body also has gas outlet, reaction cavity is communicated with gas outlet respectively, and semi-permeable membrane covers at least gas outlet.The utility model solves the problem of poor use performance of detection card box in prior art.

Description

Technical Field

[0001] This utility model relates to the field of testing equipment, and more specifically, to a testing card box. Background Technology

[0002] Traditional home molecular diagnostic cartridges employ exceptionally complex internal structures to achieve nucleic acid extraction, purification, subsequent amplification, and detection. These cartridges typically include sophisticated microfluidic channels, multiple reaction chambers, complex valve and piston systems, and integrated temperature control components. While this highly integrated design enables a degree of automation, it also introduces complex manufacturing processes, high precision requirements for component assembly, and increased failure rates, resulting in high production costs and hindering large-scale home applications. Molecular detection processes, especially nucleic acid extraction and amplification, demand a high level of environmental cleanliness; even minor contamination can lead to erroneous results. However, current home diagnostic cartridges often neglect sealing performance during long-term storage or movement, allowing test solutions to be affected by external environmental factors during transportation and storage, reducing accuracy and reliability. Insufficient sealing can also introduce airborne contaminants during use, affecting test results and increasing the risk of misdiagnosis.

[0003] Therefore, existing technologies suffer from poor performance of the detection card cartridge. Utility Model Content

[0004] The main objective of this invention is to provide a detection card box to solve the problem of poor performance of detection card boxes in the prior art.

[0005] To achieve the above objectives, according to one aspect of the present invention, a detection cartridge is provided, comprising: a cartridge body having multiple reaction chambers and at least one sample loading chamber, the sample loading chamber being in communication with the reaction chambers; a sealing cap being closable and disposed on the cartridge body, wherein when the sealing cap is pressed down on the cartridge body, the test liquid can enter the reaction chamber through the sample loading chamber; and a semi-permeable membrane, wherein the cartridge body also has an air outlet, the reaction chambers being respectively in communication with the air outlet, and the semi-permeable membrane at least covering the air outlet.

[0006] Furthermore, the sealing cap includes: a sealing cap body having an open state and a closed state, wherein when the sealing cap body switches from the open state to the closed state, the sealing cap body seals the sample dispensing chamber; and a sealing plug movably disposed on the sealing cap body, wherein when the sealing cap body switches from the closed state to the open state, the sealing plug separates from the sealing cap body, and at least a portion of the sealing plug is located within the sample dispensing chamber.

[0007] Furthermore, the reaction chamber includes: a reaction chamber body, which is connected to the gas outlet; and a first flow channel, the two ends of which are connected to the sample loading chamber and the reaction chamber body, respectively.

[0008] Furthermore, the reaction chamber also includes a second flow channel, through which the reaction chamber body is connected to the gas outlet.

[0009] Furthermore, in the height direction, the connection point between the first flow channel and the reaction chamber body is located below the connection point between the second flow channel and the reaction chamber body.

[0010] Furthermore, the second flow channel includes a first exhaust section, a second exhaust section, and a third exhaust section connected in sequence. The end of the first exhaust section away from the second exhaust section is connected to the reaction chamber body, and the end of the third exhaust section away from the second exhaust section is connected to the exhaust port. In the height direction, the third exhaust section is located below the first exhaust section; and / or the first exhaust section and the third exhaust section extend in the horizontal direction; and / or the second exhaust section extends in the vertical direction.

[0011] Furthermore, the card box body also has a third flow channel, all the first flow channels are connected to the sample dispensing chamber through the same third flow channel, and the third flow channel has at least one bend.

[0012] Furthermore, when the sealing cap is switched from the open state to the closed state, at least a portion of the sealing cap extends into the sample loading chamber and seals the sample loading chamber. The sample loading chamber includes: a cylinder having a receiving cavity and an installation opening communicating with the receiving cavity; at least a portion of the sealing cap extending into the receiving cavity through the installation opening when the sealing cap is switched from the open state to the closed state; and at least one metering groove disposed within the receiving cavity. The metering groove is funnel-shaped, with a large-diameter end at the top and a small-diameter section at the bottom, and the bottom of the metering groove having an opening communicating with the reaction chamber.

[0013] Furthermore, the main body of the card box includes: a card box base plate, the card box base plate having a reaction chamber and an air outlet, and a sample addition chamber disposed on the card box base plate, and the sample addition chamber being disposed near the periphery of the card box base plate.

[0014] Furthermore, the test cartridge also includes: an upper sealing film, which covers the top of the cartridge body, a semi-permeable membrane located between the upper sealing film and the cartridge body, and the upper sealing film having vent holes corresponding to the semi-permeable membrane; and / or a lower sealing film, which covers the bottom of the cartridge body.

[0015] Furthermore, multiple reaction chambers are arranged circumferentially around the gas outlet.

[0016] Applying the technical solution of this utility model, the detection cartridge in this application includes a cartridge body, a sealing cap, and a semi-permeable membrane. The cartridge body has multiple reaction chambers and at least one sample loading chamber, which is in communication with the reaction chambers; the sealing cap is closable on the cartridge body, and when the sealing cap is pressed down on the cartridge body, the test liquid can enter the reaction chamber through the sample loading chamber; the cartridge body also has an air outlet, and the reaction chambers are respectively in communication with the air outlet, and the semi-permeable membrane at least covers the air outlet.

[0017] When using the test cartridge of this application, since the cartridge body has a reaction chamber, the test solution can enter the sample loading chamber after being dripped into the cartridge body. Furthermore, after collecting the test solution, the sealing cap is placed on the cartridge body. As the sealing cap is pressed down on the cartridge body, the test solution can enter the reaction chamber through the sample loading chamber. After the sealing cap is closed, since the reaction chamber is connected to the vent, air inside the reaction chamber can be discharged outwards through the vent. Simultaneously, since the vent is covered with a semi-permeable membrane, the test solution inside the reaction chamber can be blocked through the semi-permeable membrane, thus preventing the test solution from escaping through the vent. Further, after the sealing cap is switched to the closed state, the sealing cap can seal the sample loading chamber to prevent gas from entering the reaction chamber, thereby ensuring the preservation effect of the test solution and the accuracy of subsequent testing. Therefore, this application simplifies the structure of the test cartridge while ensuring its sealing effect. Therefore, the detection card box in this application effectively solves the problem of poor performance of detection card boxes in the prior art. Attached Figure Description

[0018] The accompanying drawings, which form part of this application, are used to provide a further understanding of the present invention. The illustrative embodiments of the present invention and their descriptions are used to explain the present invention and do not constitute an undue limitation of the present invention. In the drawings:

[0019] Figure 1 A perspective view of a detection card box according to a specific embodiment of this application is shown;

[0020] Figure 2 It shows Figure 1 A top view of the detection card box in the middle;

[0021] Figure 3 It shows Figure 1 A bottom view of the detection card box in the middle;

[0022] Figure 4 It shows Figure 1 A schematic diagram of the main body of the detection card box in the diagram;

[0023] Figure 5 A schematic diagram of the structure of a detection card box according to yet another specific embodiment of this application is shown;

[0024] Figure 6 It shows Figure 5 A schematic diagram of the main body of the detection card box in the diagram;

[0025] Figure 7 It shows Figure 5 A perspective view of the main body of the detection card box;

[0026] Figure 8 It shows Figure 5 A schematic diagram showing the positional relationship between the main body of the detection card cartridge and the semi-permeable membrane;

[0027] Figure 9 It shows Figure 5 A schematic diagram of the sealing cover of the detection card box in the image;

[0028] Figure 10 It shows Figure 5 A structural diagram of the sealing cover of the detection card cartridge from another angle;

[0029] Figure 11 A schematic diagram showing the positional relationship between the reaction chamber body, the first refractive cavity, and the second refractive cavity of the detection cartridge in this application is shown.

[0030] The above figures include the following reference numerals:

[0031] 10. Cartridge body; 11. Reaction chamber; 111. Reaction chamber body; 112. First flow channel; 1121. Connecting section; 1122. Bubble filtration chamber; 113. Second flow channel; 1131. First exhaust section; 1132. Second exhaust section; 1133. Third exhaust section; 114. Third flow channel; 1141. Bend section; 12. Sample loading chamber; 121. Chamber cylinder; 1211. Receiving cavity; 1212. Mounting opening; 122. Quantitative trough; 13. Card holder bottom plate; 131, air outlet; 14, card holder surrounding plate; 141, exhaust opening; 15, first refraction cavity; 151, first refraction surface; 16, second refraction cavity; 161, second refraction surface; 20, sealing cover; 25, extrusion protrusion; 26, sealing surrounding plate; 261, moving part; 27, sealing cover body; 28, sealing plug; 30, sealing mold; 40, semi-permeable membrane; 50, positioning structure; 60, upper sealing membrane; 61, vent hole; 70, lower sealing membrane. Detailed Implementation

[0032] It should be noted that, unless otherwise specified, the embodiments and features described in this application can be combined with each other. The present invention will now be described in detail with reference to the accompanying drawings and embodiments.

[0033] It should be noted that, unless otherwise specified, all technical and scientific terms used in this application have the same meaning as commonly understood by one of ordinary skill in the art to which this application pertains.

[0034] In this utility model, unless otherwise stated, directional terms such as "upper," "lower," "top," and "bottom" are generally used in relation to the direction shown in the accompanying drawings, or in relation to the vertical, perpendicular, or gravitational direction of the component itself; similarly, for ease of understanding and description, "inner" and "outer" refer to the inner and outer contours of each component itself, but the above directional terms are not used to limit this utility model.

[0035] To address the issue of poor performance in existing detection card cases, this application provides a detection card case.

[0036] like Figures 1 to 4 As shown, in one specific embodiment of this application, and as... Figures 5 to 10 Unlike the illustrated embodiment, the detection cartridge in this embodiment includes a cartridge body 10, a sealing cap 20, and a semi-permeable membrane 40. The cartridge body 10 has multiple reaction chambers 11 and at least one sample loading chamber 12, which is connected to the reaction chambers 11. The sealing cap 20 is closable on the cartridge body 10. When the sealing cap 20 is pressed down on the cartridge body 10, the test liquid can enter the reaction chambers 11 through the sample loading chamber 12. The cartridge body 10 also has an air outlet 131, which is connected to the reaction chambers 11, and the semi-permeable membrane 40 at least covers the air outlet 131.

[0037] When using the test cartridge of this application, since the cartridge body 10 has a reaction chamber 11, the test solution can enter the sample loading chamber 12 after being dripped into the cartridge body 10. Furthermore, after collecting the test solution, the sealing cap 20 is placed on the cartridge body 10. During the pressing of the sealing cap 20 against the cartridge body 10, the test solution can enter the reaction chamber 11 through the sample loading chamber 12. After the sealing cap 20 is closed, since the reaction chamber 11 is connected to the air outlet 131, the air in the reaction chamber 11 can be discharged outwards through the air outlet 131. Simultaneously, since the air outlet 131 is covered by a semi-permeable membrane 40, the semi-permeable membrane 40 can block the test solution in the reaction chamber 11, thereby preventing the test solution from escaping through the air outlet 131. Furthermore, after the sealing cap 20 is switched to the closed state, it seals the sample loading chamber 12 to prevent gas from entering the reaction chamber 11, thereby ensuring the preservation effect of the test solution and the accuracy of subsequent testing. Therefore, this application simplifies the structure of the test cartridge while maintaining its sealing effect. Thus, the test cartridge in this application effectively solves the problem of poor performance in existing test cartridges.

[0038] Optionally, the sealing cap 20 has an open state and a closed state. When the sealing cap 20 is in the open state, the test liquid can be added to the sample dispensing chamber 12. When the sealing cap 20 is in the closed state, the sealing cap 20 can seal at least a portion of the cartridge body 10. Furthermore, in this embodiment, the sealing cap 20 can be divided into a connecting portion and a cap body portion. The cap body portion can be threaded into the sample dispensing chamber 12, thereby enabling the cap body portion and the sample dispensing chamber 12 to switch between the open and closed states. The connecting portion ensures that even after the cap body portion is disengaged from the sample dispensing chamber 12 and switched to the open state, the sealing cap 20 can still maintain connection with the sample dispensing chamber 12 through the connecting portion. In this embodiment, the connecting portion can have an annular structure, and the connecting portion can be sleeved onto the sample dispensing chamber 12 through the annular structure.

[0039] In one specific embodiment of this application, the sealing cap 20 includes: a sealing cap body 27, which has an open state and a closed state, and when the sealing cap body 27 switches from the open state to the closed state, the sealing cap body 27 seals the sample dispensing chamber 12; and a sealing plug 28, which is movably disposed on the sealing cap body 27, and when the sealing cap body 27 switches from the closed state to the open state, the sealing plug 28 separates from the sealing cap body 27, and at least a portion of the sealing plug 28 is located inside the sample dispensing chamber 12. In other words, in this embodiment, the cover portion includes a sealing cover body 27 and a sealing plug 28. The sealing cover body 27 can be threaded into the outer wall of the sample loading chamber 12, ensuring that the sealing cover body 27 can be detachably connected to the sample loading chamber 12. That is, the sealing cover body 27 can switch between an open and closed state. Since the sealing plug 28 is movably disposed inside the cover body 27, when the sealing cover body 27 is switched to the closed state, the sealing plug 28 can directly enter or be squeezed into the sample loading chamber 12. Therefore, when the sealing cover body 27 is switched to the open state, the sealing plug 28 can continue to seal the sample loading chamber 12, preventing contamination or leakage of the liquid inside the test cartridge. Thus, in this application, when the sealing cover 20 is in the open state, the test liquid can be added to the sample loading chamber 12, and after addition, the sealing cover 20 can be switched to the closed state. Subsequently, if the sealing cap body 27 continues to be opened, the sealing plug 28 can also seal the sample loading chamber 12.

[0040] Therefore, in this application, the sealing plug 28 can be made of flexible and deformable materials such as silicone or rubber, and in order to ensure the sealing effect of the sealing plug 28, the sealing plug 28 and the sample dispensing chamber 12 can be an interference fit.

[0041] Specifically, the reaction chamber 11 includes: a reaction chamber body 111, a cartridge bottom plate 13 having an outlet 131 communicating with the reaction chamber body 111, and a semi-permeable membrane 40 at least covering the outlet 131; a first flow channel 112, with its two ends communicating with the sample loading chamber 12 and the reaction chamber body 111, respectively. Furthermore, the reaction chamber 11 also includes a second flow channel 113, through which the reaction chamber body 111 communicates with the outlet 131. Of course, in this embodiment, a bubble filter chamber 1122 can also be provided on the first flow channel 112, as in other embodiments of this application.

[0042] Optionally, in the height direction, or in the thickness direction of the cartridge body 10, the communication position between the first flow channel 112 and the reaction chamber body 111 is located below the communication position between the second flow channel 113 and the reaction chamber body 111. With this arrangement, the test liquid and gas enter the internal opening of the reaction chamber body 111 through the first flow channel 112. Since the gas will be above the test liquid, placing the second flow channel 113 at the top of the reaction chamber body 111 allows the gas to exit the reaction chamber body 111 through the second flow channel 113, and also prevents the test liquid in the reaction chamber body 111 from entering the second flow channel 113.

[0043] Optionally, the second flow channel 113 includes a first exhaust section 1131, a second exhaust section 1132, and a third exhaust section 1133 connected in sequence. The end of the first exhaust section 1131 away from the second exhaust section 1132 is connected to the reaction chamber body 111, and the end of the third exhaust section 1133 away from the second exhaust section 1132 is connected to the exhaust port 131. In the height direction, the third exhaust section 1133 is located below the first exhaust section 1131. The first exhaust section 1131 and the third exhaust section 1133 extend horizontally, while the second exhaust section 1132 extends vertically. This arrangement allows for the rational use of the internal space of the card holder body 10, thereby avoiding excessive thickness of the card holder body 10 and facilitating the miniaturization design of the card holder body 10.

[0044] Optionally, the card box body 10 also has a third flow channel 114, all the first flow channels 112 are connected to the sample dispensing chamber 12 through the same third flow channel 114, and the third flow channel 114 has at least one bend 1141. Furthermore, when the sealing cap 20 is switched from the open state to the closed state, at least a portion of the sealing cap 20 extends into the sample loading chamber 12 and seals the sample loading chamber 12. The sample loading chamber 12 includes a cylinder 121 and at least one metering groove 122. The cylinder 121 has a receiving cavity 1211 and an installation opening 1212 communicating with the receiving cavity 1211. When the sealing cap 20 is switched from the open state to the closed state, at least a portion of the sealing cap 20 extends into the receiving cavity 1211 through the installation opening 1212. The metering groove 122 is disposed in the receiving cavity 1211. The metering groove 122 is funnel-shaped, with the top of the metering groove 122 being the large-diameter end and the bottom of the metering groove 122 being the small-diameter section. The bottom of the metering groove 122 has an opening communicating with the reaction chamber 11. Therefore, in this embodiment, the end of the third flow channel 114 away from the first flow channel 112 is connected to the small-diameter section of the metering groove 122. Furthermore, when the sealing cap 20 switches from the open state to the closed state, the air in the sample dispensing chamber 12 is compressed, which increases the pressure in the quantitative tank 122 and the third flow channel 114. This causes the test liquid to compress the inside of the cartridge body 10 and affect the sealing performance of the cartridge body 10. Therefore, in this embodiment, by providing a bending section 1141 on the third flow channel 114, the test liquid can be effectively buffered and the above problems can be solved.

[0045] Optionally, the cartridge body 10 includes a cartridge base plate 13, which has a reaction chamber 11 and an air outlet 131. A sample loading chamber 12 is disposed on the cartridge base plate 13, but unlike the previous embodiment, the sample loading chamber 12 is located near the periphery of the cartridge base plate 13. Further, optionally, multiple reaction chambers 11 are circumferentially spaced around the air outlet 131. In this application, the air outlet 131 is located near the center of the cartridge base plate 13 of the cartridge body 10. Further optionally, a groove is located at the center of the top surface of the cartridge base plate 13, and the opening on the top surface of the groove serves as the air outlet 131. The third exhaust section 1133 of the second flow channel 113 can communicate with the bottom of the groove. In this application, the connection point between the third flow channel 114 and all the first flow channels 112 is located below the groove, thus ensuring a more compact overall structure of the detection cartridge. Furthermore, in order to facilitate the connection between the third exhaust section 1133 of the second flow channel 113 and the settling tank, the end of the third exhaust section 1133 away from the second exhaust section 1132 may have a bent section, and the bent section may be parallel to the second exhaust section 1132.

[0046] Optionally, the detection cartridge also includes an upper sealing film 60, which covers the top of the cartridge base plate 13 of the cartridge body 10. A semi-permeable membrane 40 is located between the upper sealing film 60 and the cartridge base plate 13 of the cartridge body 10, and the upper sealing film 60 is provided with vent holes 61 corresponding to the semi-permeable membrane 40. Furthermore, in this application, the first exhaust section 1131 of the second flow channel 113 can communicate with the top surface of the cartridge base plate 13 and be sealed by the upper sealing film 60. Alternatively, the first exhaust section 1131 can be regarded as an opening groove with an opening facing the top surface of the cartridge base plate 13, and a flow channel structure is formed by the sealing effect of the upper sealing film 60.

[0047] Optionally, the detection card holder also includes a lower sealing film 70, which covers the bottom surface of the card holder base plate 13 of the card holder body 10. Furthermore, in this application, at least a portion of the first flow channel 112 can communicate with the bottom surface of the card holder base plate 13 and be sealed by the lower sealing film 70. Alternatively, the first flow channel 112 can be considered as an opening groove facing the bottom surface of the card holder base plate 13, forming a flow channel structure through the sealing effect of the lower sealing film 70. Of course, for the third exhaust section 1133 of the second flow channel 113, when the third exhaust section 1133 is offset from the first flow channel 112 in the thickness direction of the card holder body 10, the positional relationship and arrangement of the third exhaust section 1133, the third flow channel 114, the bottom surface of the card holder base plate 13 of the card holder body 10, and the lower sealing film 70 can be the same as those of the first flow channel 112. The special design of the first flow channel 112 and the first exhaust section 1131 corresponding to the top and bottom surfaces of the card box base plate 13 can effectively reduce the overall thickness of the card box base plate 13, thereby facilitating the miniaturization design of the detection card box.

[0048] like Figures 5 to 10 As shown, in another specific embodiment of this application, unlike the above embodiment, the cartridge body 10 also has at least one sample dispensing chamber 12. The sample dispensing chamber 12 includes a chamber cylinder 121 and at least one quantitative groove 122. The chamber cylinder 121 has a receiving cavity 1211 and an installation opening 1212 communicating with the receiving cavity 1211. When the sealing cover 20 is switched from the open state to the closed state, at least a portion of the sealing cover 20 extends into the receiving cavity 1211 through the installation opening 1212. The quantitative groove 122 is disposed in the receiving cavity 1211 and communicates with the reaction chamber 11.

[0049] Specifically, the card box body 10 includes a card box bottom plate 13 and a card box surrounding plate 14. The card box bottom plate 13 has a reaction chamber 11 and a sample loading chamber 12 is disposed on the card box bottom plate 13. The card box surrounding plate 14 is disposed around the periphery of the card box bottom plate 13 and has at least one exhaust opening 141.

[0050] Specifically, the detection cartridge also includes a semi-permeable membrane 40, and the reaction chamber 11 includes a reaction chamber body 111 and a first flow channel 112. The cartridge bottom plate 13 has an outlet 131 communicating with the reaction chamber body 111, and the semi-permeable membrane 40 at least covers the outlet 131; the two ends of the first flow channel 112 are respectively connected to the metering groove 122 and the reaction chamber body 111.

[0051] Furthermore, in this embodiment, when there are multiple reaction chambers 11, the multiple reaction chambers 11 can be arranged circumferentially around the chamber cylinder 121. At this time, the semipermeable membrane 40 can be designed as an annular shape, so that the reaction chamber body 111 of all the reaction chambers 11 can be covered by only one semipermeable membrane 40.

[0052] In other words, in this embodiment, the sample loading chamber 12 is only used to add the test solution and does not serve a venting function. When the test solution added to the sample loading chamber 12 enters the metering tank 122, it can enter the reaction chamber body 111 through the first flow channel 112 under its own gravity. Simultaneously, since the reaction chamber body 111 is covered by a semi-permeable membrane 40, the gas inside the reaction chamber body 111 can be discharged through the semi-permeable membrane 40. Therefore, in this embodiment, the function of the semi-permeable membrane 40 is to allow gas to pass through but not the test solution. Therefore, in this embodiment, it is not necessary to add a second flow channel 113 as in the previous embodiment. Furthermore, when the gas inside the reaction chamber body 111 passes through the semi-permeable membrane 40 and enters the space enclosed by the cartridge body and the cartridge enclosure 14, it can be discharged from the cartridge body 10 through the vent opening 141 of the cartridge enclosure 14. When the sealing cover 20 is switched to the closed state, the sealing cover 20 can cover the top of the card box enclosure 14 and seal the space enclosed by the card box enclosure 14 and the card box bottom plate 13, thereby ensuring the sealing effect of the test card box.

[0053] Furthermore, in this application, the semipermeable membrane 40 can be made of expanded polytetrafluoroethylene, or it can be a polyurethane microporous membrane. Of course, the semipermeable membrane 40 can also be supported by a composite reinforced material, or the semipermeable membrane 40 can be a polymer coated membrane.

[0054] Preferably, the first flow channel 112 includes at least two connected sections 1121, and a bubble filter chamber 1122 is provided between the at least two interconnected connected sections 1121.

[0055] Specifically, the sealing cover 20 is provided with a compression protrusion 25 corresponding to the receiving cavity 1211, and the sealing cover 20 is provided with a sealing enclosure 26 corresponding to the cartridge enclosure 14. When the sealing cover 20 is in the closed state, at least a portion of the compression protrusion 25 extends into the receiving cavity 1211 and seals the receiving cavity 1211, and at least a portion of the sealing enclosure 26 extends into the annular space enclosed by the cartridge enclosure 14 and seals the annular space and the exhaust opening 141. This arrangement ensures that during the process of switching the sealing cover 20 to the closed state, that is, during the process of the sealing cover 20 covering the cartridge enclosure 14, the compression protrusion 25 can compress the gas in the chamber 121, thereby facilitating the entry of the test liquid into the interior of the reaction chamber body 111. The sealing enclosure 26 can seal the exhaust opening 141 of the cartridge enclosure 14.

[0056] Optionally, at least the portion of the extrusion protrusion 25 corresponding to the bottom surface of the receiving cavity 1211 is made of a deformable material. For example, the extrusion protrusion 25 can be made of materials such as rubber or silicone. This arrangement ensures that the extrusion protrusion 25 can more easily enter the interior of the hopper 121.

[0057] Optionally, the sealing plate 26 is provided with a movable member 261 corresponding to the exhaust opening 141, at least a portion of which can enter or exit the sealing plate 26. With this arrangement, during the process of the sealing cover 20 switching to the closed state, the movable member 261 is first squeezed by the cartridge enclosure 14 and pushed into the interior of the sealing plate 26. As the sealing cover 20 continues to move, that is, as it continues to move axially along the cylindrical area enclosed by the cartridge enclosure 14, the position of the sealing plate 26 corresponding to the movable member 261 gradually aligns with the exhaust opening 141 on the cartridge enclosure 14. At this point, the movable member 261 is no longer squeezed by the cartridge enclosure 14, so it can exit the sealing plate 26 and enter the exhaust opening 141 under the reset action of the reset member or other structures within the sealing plate 26, thereby further sealing the opening and ensuring the sealing effect of the test cartridge.

[0058] Optionally, the cartridge enclosure 14 and the sealing enclosure 26 have mutually cooperating positioning structures 50. In this embodiment, the positioning structure 50 can be a positioning notch provided on the top of the enclosure and a positioning protrusion provided on the circumferential outer wall of the sealing enclosure 26 and extending radially. With this arrangement, during the process of the sealing cover 20 being placed on the cartridge body, the mutual cooperation of the positioning notch and the positioning protrusion makes it easier to accurately locate the sealing cover 20, thereby facilitating the alignment of the vent opening 141 and the movable part 261. At the same time, the cooperation of the positioning notch and the positioning protrusion also serves to indicate when the sealing cover 20 is in place.

[0059] In this application, regarding the relationship between the reaction chamber 11 and the metering tank 122, there are multiple reaction chambers 11 and multiple metering tanks 122, with each multiple reaction chamber 11 corresponding to a different metering tank 122, and the multiple reaction chambers 11 are arranged at intervals around the chamber cylinder 121. Therefore, this arrangement ensures that different metering tanks 122 can hold different test liquids, and that they can be detected through different reaction chambers 11.

[0060] Optionally, the test card holder also includes a sealing mold 30, which at least covers the bottom surface of the card holder body 10. This arrangement effectively ensures the sealing effect of the test card holder.

[0061] It should be noted that, as Figure 11 As shown, for the detection cartridge in this application, the reaction chamber 11 further includes a first refractive cavity 15 and a second refractive cavity 16 symmetrically arranged about the reaction chamber body 111. The first refractive cavity 15 has a first refractive surface 151 corresponding to the reaction chamber body 111, and the second refractive cavity 16 has a second refractive surface 161 corresponding to the reaction chamber body 111. With this arrangement, when the reaction chamber body 111 is filled with the test liquid, when detecting the test liquid in the reaction chamber body 111, the detection light source can shine from the bottom or top of the detection cartridge toward the inside of the first refractive cavity 15, and the detection light source can be refracted into the inside of the reaction chamber body 111 through the first refractive surface 151, thereby illuminating the test liquid in the reaction chamber body 111. At this time, the fluorescence generated by the test liquid being irradiated can be refracted through the second refractive surface 161 to the receiver at the bottom or top of the second refractive cavity 16, thereby realizing the detection of the test liquid.

[0062] As can be seen from the above description, the embodiments of this utility model achieve the following technical effects:

[0063] 1. Effectively solves the problem of poor performance of detection card boxes in existing technologies;

[0064] 2. Simple structure and stable performance.

[0065] Obviously, the embodiments described above are only some embodiments of this utility model, and not all embodiments. Based on the embodiments of this utility model, all other embodiments obtained by those skilled in the art without creative effort should fall within the protection scope of this utility model.

[0066] It should be noted that the terminology used herein is for the purpose of describing particular embodiments only and is not intended to limit the exemplary embodiments according to this application. As used herein, the singular form is intended to include the plural form as well, unless the context clearly indicates otherwise. Furthermore, it should be understood that when the terms "comprising" and / or "including" are used in this specification, they indicate the presence of features, steps, operations, devices, components, and / or combinations thereof.

[0067] It should be noted that the terms "first," "second," etc., used in the specification, claims, and accompanying drawings of this application are used to distinguish similar objects and are not necessarily used to describe a specific order or sequence. It should be understood that such data can be interchanged where appropriate so that the embodiments of this application described herein can be implemented in sequences other than those illustrated or described herein.

[0068] The above description is merely a preferred embodiment of this utility model and is not intended to limit the utility model. Various modifications and variations can be made to this utility model by those skilled in the art. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of this utility model should be included within the protection scope of this utility model.

Claims

1. A detection card holder, characterized in that, include: The cartridge body (10) has multiple reaction chambers (11) and at least one sample dispensing chamber (12), the sample dispensing chamber (12) being connected to the reaction chambers (11); A sealing cap (20) is provided on the cartridge body (10) in an openable and closable manner. When the sealing cap (20) is pressed down on the cartridge body (10), the test liquid can enter the reaction chamber (11) through the sample loading chamber (12). The semi-permeable membrane (40) and the card box body (10) also have an air outlet (131), the reaction chamber (11) is connected to the air outlet (131), and the semi-permeable membrane (40) at least covers the air outlet (131).

2. The test cartridge of claim 1, wherein, The sealing cap (20) includes: The sealing cap body (27) has an open state and a closed state. When the sealing cap body (27) switches from the open state to the closed state, the sealing cap body (27) seals the sample dispensing chamber (12). A sealing plug (28) is movably disposed on the sealing cap body (27). When the sealing cap body (27) switches from the closed state to the open state, the sealing plug (28) separates from the sealing cap body (27), and at least a portion of the sealing plug (28) is located in the sample dispensing chamber (12).

3. The test cartridge of claim 1, wherein, The reaction chamber (11) includes: The reaction chamber body (111) is connected to the air outlet (131); The first flow channel (112) is connected at both ends to the sample loading chamber (12) and the reaction chamber body (111), respectively.

4. The detection card holder according to claim 3, characterized in that, The reaction chamber (11) further includes a second flow channel (113), and the reaction chamber body (111) is connected to the air outlet (131) through the second flow channel (113).

5. The detection card holder according to claim 4, characterized in that, In the height direction, the communication position between the first flow channel (112) and the reaction chamber body (111) is located below the communication position between the second flow channel (113) and the reaction chamber body (111).

6. The test cartridge of claim 4, wherein, The second flow channel (113) includes a first exhaust section (1131), a second exhaust section (1132), and a third exhaust section (1133) connected in sequence. The end of the first exhaust section (1131) away from the second exhaust section (1132) is connected to the reaction chamber body (111), and the end of the third exhaust section (1133) away from the second exhaust section (1132) is connected to the exhaust port (131). In the vertical direction, the third exhaust section (1133) is located below the first exhaust section (1131); and / or The first exhaust section (1131) and the third exhaust section (1133) extend in a horizontal direction; and / or The second exhaust section (1132) extends in the vertical direction.

7. The test cartridge of claim 3, wherein The card box body (10) also has a third flow channel (114), all the first flow channels (112) are connected to the sample loading chamber (12) through the same third flow channel (114), and the third flow channel (114) has at least one bend (1141).

8. The test cartridge of any one of claims 1 to 7, wherein, When the sealing cap (20) switches from the open state to the closed state, at least a portion of the sealing cap (20) extends into the sample dispensing chamber (12) and seals the sample dispensing chamber (12), the sample dispensing chamber (12) comprising: A silo (121) having a receiving cavity (1211) and an installation opening (1212) communicating with the receiving cavity (1211), wherein when the sealing cover (20) is switched from the open state to the closed state, at least a portion of the sealing cover (20) extends into the receiving cavity (1211) through the installation opening (1212); At least one metering groove (122) is disposed in the receiving cavity (1211). The metering groove (122) is funnel-shaped, with the top of the metering groove (122) being the large-diameter end and the bottom of the metering groove (122) being the small-diameter section. The bottom of the metering groove (122) has an opening communicating with the reaction cavity (11).

9. The test cartridge of any one of claims 1 to 7, wherein, The card box body (10) includes: Card box bottom plate (13), the card box bottom plate (13) has the reaction chamber (11) and the air outlet (131), the sample filling chamber (12) is disposed on the card box bottom plate (13), and the sample filling chamber (12) is disposed close to the periphery of the card box bottom plate (13).

10. The test cartridge of any one of claims 1 to 7, wherein, The detection cartridge also includes: An upper sealing film (60) is provided, which covers the top of the card holder body (10). A semi-permeable membrane (40) is located between the upper sealing film (60) and the card holder body (10), and the upper sealing film (60) is provided with vent holes (61) corresponding to the semi-permeable membrane (40); and / or A lower sealing film (70) is provided on the bottom surface of the card holder body (10).

11. The detection cartridge according to any one of claims 1 to 7, characterized in that, The plurality of reaction chambers (11) are arranged circumferentially around the gas outlet (131).

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