Detection cartridge

Abstract

The utility model provides a kind of detection card box.The detection card box includes: card box main body, card box main body has at least one reaction cavity;Sealing cover, sealing cover is set on card box main body with open and close, sealing cover has open state and closed state, when sealing cover is switched from open state to closed state, gas in reaction cavity is discharged card box main body, and sealing cover seals at least a part of card box main body.The utility model solves the problem of poor use performance of detection card box in the prior art.

Description

Technical Field

[0001] This utility model relates to the field of testing equipment, and more specifically, to a testing card box. Background Technology

[0002] Traditional home molecular diagnostic cartridges employ exceptionally complex internal structures to achieve nucleic acid extraction, purification, subsequent amplification, and detection. These cartridges typically include sophisticated microfluidic channels, multiple reaction chambers, complex valve and piston systems, and integrated temperature control components. While this highly integrated design enables a degree of automation, it also introduces complex manufacturing processes, high precision requirements for component assembly, and increased failure rates, resulting in high production costs and hindering large-scale home applications. Molecular detection processes, especially nucleic acid extraction and amplification, demand a high level of environmental cleanliness; even minor contamination can lead to erroneous results. However, current home diagnostic cartridges often neglect sealing performance during long-term storage or movement, allowing test solutions to be affected by external environmental factors during transportation and storage, reducing accuracy and reliability. Insufficient sealing can also introduce airborne contaminants during use, affecting test results and increasing the risk of misdiagnosis.

[0003] Therefore, existing technologies suffer from poor performance of the detection card cartridge. Utility Model Content

[0004] The main objective of this invention is to provide a detection card box to solve the problem of poor performance of detection card boxes in the prior art.

[0005] To achieve the above objectives, according to one aspect of the present invention, a detection cartridge is provided, comprising: a cartridge body having multiple reaction chambers and at least one sample loading chamber, the sample loading chamber being in communication with the reaction chambers; a sealing cap being closably disposed on the cartridge body, wherein when the sealing cap is pressed down on the cartridge body, the test liquid can enter the reaction chamber through the sample loading chamber; the sealing cap having an open state and a closed state, wherein when the sealing cap is in the open state, the test liquid can be added to the sample loading chamber, and when the sealing cap is in the closed state, the sealing cap can seal at least a portion of the cartridge body.

[0006] Furthermore, when the sealing cap is switched from the open state to the closed state, at least a portion of the sealing cap extends into the sample loading chamber and seals the sample loading chamber. The sample loading chamber includes: a chamber cylinder having a receiving cavity and an installation opening communicating with the receiving cavity; at least a portion of the sealing cap extending into the receiving cavity through the installation opening when the sealing cap is switched from the open state to the closed state; and at least one metering groove, at least a portion of which is disposed on the bottom surface of the receiving cavity and communicates with the reaction chamber.

[0007] Furthermore, the gas in the reaction chamber can be discharged from the cartridge body through the sample loading chamber, which also includes at least one first exhaust channel. The first exhaust channel is disposed in the receiving chamber, and the reaction chamber is connected to the quantitative tank and the first exhaust channel respectively.

[0008] Furthermore, the sealing cap has a second exhaust channel. When the sealing cap is in the closed state, one end of the second exhaust channel is fitted onto the end of the first exhaust channel away from the reaction chamber and communicates with the first exhaust channel.

[0009] Furthermore, when the sealing cap is closed, the silo seals the other end of the second exhaust passage.

[0010] Furthermore, the sealing cover includes a sealing section and an extension section disposed on the sealing section toward the first exhaust passage, at least a portion of the second exhaust passage is located in the sealing section, at least another portion of the second exhaust passage is located in the extension section, and the end of the first exhaust passage away from the reaction chamber can enter or exit the extension section.

[0011] Furthermore, the second exhaust passage includes multiple first connecting sections and one second connecting section. The first connecting sections are located inside the sealing section, and the second connecting section is located inside the extension section. The circumferential sidewall of the sealing section is provided with different exhaust ports corresponding to different first connecting sections.

[0012] Furthermore, the inner circumferential wall of the silo near the reaction chamber has a cylindrical protrusion. When the sealing cover is closed, the side of the sealing section facing the extension section abuts against the top surface of the cylindrical protrusion, and the circumferential sidewall of the sealing section with the exhaust port abuts against the inner circumferential wall of the silo.

[0013] Furthermore, the inner circumferential wall of the silo near the reaction chamber has a cylindrical protrusion, and a first exhaust channel is disposed within the cylindrical protrusion. Different first exhaust channels are respectively connected to at least one different reaction chamber.

[0014] Furthermore, at least a portion of the sealing cap extends into the space enclosed by the cylindrical protrusion and abuts against the circumferential inner sidewall of the cylindrical protrusion, and the sealing cap has at least two stepped surfaces, with the periphery of the mounting opening and the top surface of the cylindrical protrusion abutting against different stepped surfaces respectively.

[0015] Furthermore, the reaction chamber includes: a reaction chamber body; a first flow channel, the two ends of which are connected to the metering tank and the reaction chamber body respectively; and a second flow channel, the two ends of which are connected to the first exhaust channel and the reaction chamber body respectively. When the sealing cover is pressed down, the gas in the reaction chamber body enters the first exhaust channel through the second flow channel and is discharged from the cartridge body.

[0016] Furthermore, the first flow channel includes at least two connected sections, and a bubble filter chamber is provided between the at least two interconnected connected sections.

[0017] Furthermore, the main body of the card box includes: a card box base plate, the card box base plate having a reaction chamber, and a sample dispensing chamber disposed on the card box base plate.

[0018] Furthermore, the card box body includes: a card box surround plate, which is arranged around the periphery of the card box bottom plate, and the card box surround plate has at least one venting opening.

[0019] Furthermore, the detection cartridge also includes a semi-permeable membrane, and the reaction chamber includes: a reaction chamber body, a cartridge base plate having an outlet communicating with the reaction chamber body, and the semi-permeable membrane at least covering the outlet; a first flow channel, the two ends of which are respectively connected to the metering tank and the reaction chamber body.

[0020] Furthermore, the first flow channel includes at least two connected sections, and a bubble filter chamber is provided between the at least two interconnected connected sections.

[0021] Furthermore, the sealing cover is provided with a compression protrusion corresponding to the receiving cavity, and the sealing cover is provided with a sealing plate corresponding to the card box surrounding plate. When the sealing cover is in the closed state, at least a portion of the compression protrusion extends into the receiving cavity and seals the receiving cavity, and at least a portion of the sealing plate extends into the annular space formed by the card box surrounding plate and seals the annular space and the vent opening.

[0022] Furthermore, the reaction chamber also includes a second flow channel, through which the reaction chamber body is connected to the gas outlet.

[0023] Furthermore, in the height direction, the connection point between the first flow channel and the reaction chamber body is located below the connection point between the second flow channel and the reaction chamber body.

[0024] Furthermore, the second flow channel includes a first exhaust section, a second exhaust section, and a third exhaust section connected in sequence. The end of the first exhaust section away from the second exhaust section is connected to the reaction chamber body, and the end of the third exhaust section away from the second exhaust section is connected to the exhaust port. In the height direction, the third exhaust section is located below the first exhaust section; and / or the first exhaust section and the third exhaust section extend in the horizontal direction; and / or the second exhaust section extends in the vertical direction.

[0025] Furthermore, the card box body also has a third flow channel, all the first flow channels are connected to the sample dispensing chamber through the same third flow channel, and the third flow channel has at least one bend.

[0026] Furthermore, the test cartridge also includes: an upper sealing film, which covers the top of the cartridge bottom plate, a semi-permeable membrane located between the upper sealing film and the cartridge bottom plate, and the upper sealing film having vent holes corresponding to the semi-permeable membrane; and / or a lower sealing film, which covers the bottom surface of the cartridge bottom plate.

[0027] Furthermore, multiple reaction chambers are arranged circumferentially around the gas outlet.

[0028] Furthermore, the sealing cap includes: a sealing cap body having an open state and a closed state, wherein when the sealing cap body switches from the open state to the closed state, the sealing cap body seals the sample dispensing chamber; and a sealing plug movably disposed on the sealing cap body, wherein when the sealing cap body switches from the closed state to the open state, the sealing plug separates from the sealing cap body, and at least a portion of the sealing plug is located within the sample dispensing chamber.

[0029] Furthermore, the reaction chamber also includes a first refractive cavity and a second refractive cavity disposed on both sides of the reaction chamber body. The first refractive cavity has a first refractive surface corresponding to the reaction chamber body, and the second refractive cavity has a second refractive surface corresponding to the reaction chamber body.

[0030] Furthermore, there are multiple metering tanks, and multiple reaction chambers and multiple metering tanks are connected in a one-to-one correspondence; and / or multiple reaction chambers are arranged at intervals around the bin; and / or the volume of the metering tank is greater than the volume of the reaction chamber.

[0031] Applying the technical solution of this utility model, the test cartridge in this application includes a cartridge body and a sealing cap. The cartridge body has multiple reaction chambers and at least one sample dispensing chamber, which is in communication with the reaction chambers; the sealing cap is closable on the cartridge body, and when the sealing cap is pressed down on the cartridge body, the test liquid can enter the reaction chamber through the sample dispensing chamber; the sealing cap has an open state and a closed state, when the sealing cap is in the open state, the test liquid can be added to the sample dispensing chamber, and when the sealing cap is in the closed state, the sealing cap can seal at least a portion of the cartridge body.

[0032] When using the test cartridge of this application, since the cartridge body has a reaction chamber, the test solution can enter the sample loading chamber after being dripped into the cartridge body. Furthermore, after collecting the test solution, the sealing cap is placed on the cartridge body. As the sealing cap is pressed down on the cartridge body, the test solution can enter the reaction chamber through the sample loading chamber. After the sealing cap is closed, it switches from an open state to a closed state. During the process of switching the sealing cap to the closed state, gas in the reaction chamber can be released. Furthermore, after the sealing cap switches to the closed state, it can seal at least a portion of the cartridge body to prevent gas from entering the reaction chamber, thereby ensuring the preservation effect of the test solution and the accuracy of subsequent testing. Therefore, this application simplifies the structure of the test cartridge while ensuring its sealing effect. Thus, the test cartridge of this application effectively solves the problem of poor performance in existing test cartridges. Attached Figure Description

[0033] The accompanying drawings, which form part of this application, are used to provide a further understanding of the present invention. The illustrative embodiments of the present invention and their descriptions are used to explain the present invention and do not constitute an undue limitation of the present invention. In the drawings:

[0034] Figure 1 A schematic diagram of the structure of a detection card box according to a specific embodiment of this application is shown;

[0035] Figure 2 It shows Figure 1 A perspective view of the main body of the detection card box;

[0036] Figure 3 It shows Figure 1 A cross-sectional view of the main body of the detection card box;

[0037] Figure 4 It shows Figure 1 A perspective view of the sealed cover of the test card cartridge;

[0038] Figure 5 It shows Figure 1 A cross-sectional view of the detection card box in the middle;

[0039] Figure 6 A schematic diagram of the structure of a detection card box according to another specific embodiment of this application is shown;

[0040] Figure 7 It shows Figure 6 A perspective view of the main body of the detection card box;

[0041] Figure 8 It shows Figure 6 A cross-sectional view of the main body of the detection card box;

[0042] Figure 9 It shows Figure 6 A cross-sectional view of the sealing cover of the detection card cartridge;

[0043] Figure 10 A schematic diagram of the structure of a detection card box according to yet another specific embodiment of this application is shown;

[0044] Figure 11 It shows Figure 10 A schematic diagram of the main body of the detection card box in the diagram;

[0045] Figure 12 It shows Figure 10 A perspective view of the main body of the detection card box;

[0046] Figure 13 It shows Figure 10 A schematic diagram showing the positional relationship between the main body of the detection card cartridge and the semi-permeable membrane;

[0047] Figure 14 It shows Figure 10 A schematic diagram of the sealing cover of the detection card box in the image;

[0048] Figure 15 It shows Figure 10 A structural diagram of the sealing cover of the detection card cartridge from another angle;

[0049] Figure 16 This paper shows a schematic diagram illustrating the positional relationship between the reaction chamber body, the first refractive cavity, and the second refractive cavity of the detection cartridge in this application;

[0050] Figure 17 A perspective view of a detection card box according to yet another specific embodiment of this application is shown;

[0051] Figure 18 It shows Figure 17 A top view of the detection card box in the middle;

[0052] Figure 19 It shows Figure 17 A bottom view of the detection card box in the middle;

[0053] Figure 20 It shows Figure 17 A schematic diagram of the main body of the detection card box.

[0054] The above figures include the following reference numerals:

[0055] 10. Cartridge body; 11. Reaction chamber; 111. Reaction chamber body; 112. First flow channel; 1121. Connecting section; 1122. Bubble filtration chamber; 113. Second flow channel; 1131. First exhaust section; 1132. Second exhaust section; 1133. Third exhaust section; 114. Third flow channel; 1141. Bend section; 12. Sample loading chamber; 121. Chamber cylinder; 1211. Receiving cavity; 1212. Mounting opening; 1213. Cylindrical protrusion; 122. Quantitative groove; 123. First exhaust channel; 13. Cartridge bottom plate; 131. Gas outlet; 14. 141. Card box enclosure; 15. Exhaust opening; 16. First refraction cavity; 17. First refraction surface; 18. Second refraction cavity; 19. Second refraction surface; 20. Sealing cover; 21. Second exhaust channel; 22. First connecting section; 23. Second connecting section; 24. Sealing section; 25. Extension section; 26. Step surface; 27. Extrusion protrusion; 28. Sealing enclosure; 29. ​​Movable part; 20. Sealing cover body; 21. Sealing plug; 22. Sealing mold; 33. Semi-permeable membrane; 44. Positioning structure; 55. Upper sealing membrane; 66. Vent hole; 77. Lower sealing membrane. Detailed Implementation

[0056] It should be noted that, unless otherwise specified, the embodiments and features described in this application can be combined with each other. The present invention will now be described in detail with reference to the accompanying drawings and embodiments.

[0057] It should be noted that, unless otherwise specified, all technical and scientific terms used in this application have the same meaning as commonly understood by one of ordinary skill in the art to which this application pertains.

[0058] In this utility model, unless otherwise stated, directional terms such as "upper," "lower," "top," and "bottom" are generally used in relation to the direction shown in the accompanying drawings, or in relation to the vertical, perpendicular, or gravitational direction of the component itself; similarly, for ease of understanding and description, "inner" and "outer" refer to the inner and outer contours of each component itself, but the above directional terms are not used to limit this utility model.

[0059] To address the issue of poor performance in existing detection card cases, this application provides a detection card case.

[0060] like Figures 1 to 20 As shown, the test cartridge in this application includes a cartridge body 10 and a sealing cap 20. The cartridge body 10 has at least one reaction chamber 11 and at least one sample dispensing chamber 12, with the sample dispensing chamber 12 communicating with the reaction chamber 11. The sealing cap 20 is closably disposed on the cartridge body 10. When the sealing cap 20 is pressed down on the cartridge body 10, the test liquid can enter the reaction chamber 11 through the sample dispensing chamber 12. The sealing cap 20 has an open state and a closed state. When the sealing cap 20 is in the open state, the test liquid can be added to the sample dispensing chamber 12. When the sealing cap 20 is in the closed state, the sealing cap 20 can seal at least a portion of the cartridge body 10.

[0061] When using the test cartridge of this application, since the cartridge body 10 has a reaction chamber 11, after the test solution is dripped into the cartridge body 10, the test solution can enter the sample loading chamber 12. Furthermore, after the test solution is collected, the sealing cap 20 is placed on the cartridge body 10. During the pressing of the sealing cap 20 against the cartridge body 10, the test solution can enter the reaction chamber 11 through the sample loading chamber 12. After the sealing cap 20 is closed, it switches from an open state to a closed state. During the switching of the sealing cap 20 to the closed state, gas in the reaction chamber can be released. Furthermore, after the sealing cap 20 switches to the closed state, it can seal at least a portion of the cartridge body 10 to prevent gas from entering the reaction chamber 11, thereby ensuring the preservation effect of the test solution and the accuracy of subsequent testing. Therefore, this application can simplify the structure of the test cartridge while ensuring its sealing effect. Therefore, the detection card box in this application effectively solves the problem of poor performance of detection card boxes in the prior art.

[0062] Optionally, the cartridge body 10 also has at least one sample loading chamber 12, which is connected to the reaction chamber 11. The sample loading chamber 12 allows the test liquid to enter the reaction chamber 11 through the sample loading chamber 12, while the gas in the reaction chamber 11 can be discharged from the cartridge body 10 through the sample loading chamber 12. In other words, in this embodiment, there can be at least two connecting structures between the reaction chamber 11 and the sample loading chamber 12. One connecting structure allows the test liquid to enter the interior of the reaction chamber 11 from the sample loading chamber 12, while the other connecting structure allows the gas in the reaction chamber 11 to be discharged.

[0063] Optionally, when the sealing cap 20 is switched from the open state to the closed state, at least a portion of the sealing cap 20 extends into the sample loading chamber 12 and seals the sample loading chamber 12. That is, in this embodiment, after the test liquid is added to the sample loading chamber 12, during the process of switching the sealing cap 20 from the open state to the closed state, at least a portion of the sealing cap 20 can extend into the interior of the sample loading chamber 12. As the sealing cap 20 extends in, the test liquid is subjected to its own gravity and the squeezing effect of the sealing cap 20 on the gas in the sample loading chamber 12, thereby allowing the test liquid to enter the interior of the reaction chamber 11. Furthermore, the magnetic test liquid can also squeeze the gas in the reaction chamber 11 into the sample loading chamber 12 and discharge it. Thus, when the sealing cap 20 is in the closed state, the sealing cap 20 can seal the sample loading chamber 12 while preventing gas from entering the interior of the reaction chamber 11.

[0064] Optionally, the sample loading chamber 12 includes a cylinder 121, at least one metering groove 122, and at least one first exhaust channel 123. The cylinder 121 has a receiving cavity 1211 and an installation opening 1212 communicating with the receiving cavity 1211. When the sealing cap 20 is switched from the open state to the closed state, at least a portion of the sealing cap 20 extends into the receiving cavity 1211 through the installation opening 1212. At least a portion of the metering groove 122 is disposed on the bottom surface of the receiving cavity 1211, or in other words, the bottom surface of the cylinder 121 has a portion of the metering groove 122, while the other portion of the metering groove 122 is located inside the cartridge body and communicates with the reaction chamber 11. This arrangement ensures that the test liquid can enter the metering groove 122 through the cylinder 121, while preventing the metering groove 122 from being easily contaminated due to its large exposed area. The first exhaust channel 123 is disposed inside the receiving cavity 1211, and the reaction chamber 11 communicates with the metering groove 122 and the first exhaust channel 123 respectively. In other words, in this application, the test solution enters the reaction chamber 11 through the metering tank 122, while the air inside the reaction chamber 11 can be discharged from the reaction chamber 11 and enter the first exhaust channel 123, and finally discharged from the end of the first exhaust channel 123 away from the reaction chamber 11. Therefore, in this application, the test solution in the metering tank 122 can enter the reaction chamber 11 under its own gravity or under the squeezing action of the sealing cap 20 on the internal space of the sample loading chamber 12.

[0065] In one specific embodiment of this application, the metering groove 122 is teardrop-shaped, and the tip of the teardrop-shaped metering groove 122 is located on the bottom surface of the receiving cavity 1211.

[0066] like Figures 1 to 5As shown, in a specific embodiment of this application, the sealing cover 20 has a second exhaust channel 21. When the sealing cover 20 is in the closed state, one end of the second exhaust channel 21 is sleeved on the end of the first exhaust channel 123 away from the reaction chamber 11 and communicates with the first exhaust channel 123. That is, in this embodiment, after the gas in the reaction chamber 11 is discharged from the reaction chamber 11, it is discharged sequentially through the first exhaust channel 123 and the second exhaust channel 21. At the same time, when the sealing cover 20 is in the closed state, the chamber 121 seals the other end of the second exhaust channel 21. Furthermore, by setting one end of the second exhaust channel 21 to be sleeved on the end of the first exhaust channel 123 away from the reaction chamber 11, the sealing effect between the first exhaust channel 123 and the second exhaust channel 21 can be effectively guaranteed, thereby ensuring that the gas in the reaction chamber 11 can only be discharged from the end of the second exhaust channel 21 away from the first exhaust channel 123, and not from the connection between the first exhaust channel 123 and the second exhaust channel 21, thereby further effectively guaranteeing the sealing effect of the detection card box. Optionally, the sealing cap 20 includes a sealing section 22 and an extension section 23 disposed on the sealing section 22 facing the first exhaust passage 123. At least a portion of the second exhaust passage 21 is located in the sealing section 22, and at least another portion of the second exhaust passage 21 is located in the extension section 23. The end of the first exhaust passage 123 away from the reaction chamber 11 can enter or exit the extension section 23. That is, when the sealing cap 20 is in the closed state, the second exhaust passage 21 is fitted onto the first exhaust passage 123 through the portion located in the extension section 23.

[0067] Optionally, the extension direction of the portion of the second exhaust passage 21 located in the extension section 23 is the same as the extension direction of the first exhaust passage 123. This arrangement also ensures that the portion of the second exhaust passage 21 located in the extension section 23 can be more easily fitted onto the first exhaust passage 123.

[0068] Optionally, the extension direction of the portion of the second exhaust passage 21 located in the sealing section 22 has an angle greater than 0 degrees with the extension direction of the first exhaust passage 123. In one specific embodiment of this application, the angle between the extension direction of the portion of the second exhaust passage 21 located in the sealing section 22 and the extension direction of the first exhaust passage 123 is 90 degrees. Therefore, the angle between the extension direction of the portion of the second exhaust passage 21 located in the sealing section 22 and the extension direction of the portion of the second exhaust passage 21 located in the extension section 23 is also 90 degrees.

[0069] Optionally, the axis of the first exhaust passage 123 coincides with the axis of the chamber 121. This arrangement allows for a more regular and compact structural layout within the chamber 121, which is beneficial for miniaturizing the detection cartridge.

[0070] Furthermore, in one specific embodiment of this application, the sealing section 22, extension section 23, hopper 121, and first exhaust channel 123 of the sealing cover 20 are all cylindrical. The portion of the second exhaust channel 21 located in the sealing section 22 of the sealing cover 20 extends radially along the sealing section 22, while the portion of the second channel located in the extension section 23 of the sealing cover 20 extends axially along the extension section 23. At this time, the axis of the extension section 23, the axis of the portion of the second channel located in the extension section 23, the axis of the first exhaust channel 123, and the axis of the hopper 121 coincide. Simultaneously, when there are multiple metering grooves 122, the multiple metering grooves 122 are circumferentially spaced around the first exhaust channel 123.

[0071] Optionally, the metering groove 122 is located near the bottom end of the first exhaust channel 123. Furthermore, in this application, regarding the location of the metering groove 122, the hopper 121 is a cylindrical tube standing upright on the bottom surface of the card holder body 10, and the portion of the bottom surface of the card holder body 10 located inside the hopper 121 has the metering groove 122. Additionally, in this application, the hopper 121 and the card holder body 10 can be an integrally formed structure.

[0072] It should be noted that, in order to ensure the sealing effect between the first exhaust channel 123 and the second exhaust channel 21, after the second exhaust channel 21 is fitted onto the first exhaust channel 123, the outer circumferential wall of the first exhaust channel 123 abuts against the inner circumferential wall of the second exhaust channel 21, thereby preventing gas from leaking out from here.

[0073] Furthermore, in this embodiment, in the vertical direction, or in the axial direction of the first exhaust channel 123, the bottom end of the first exhaust channel 123 is connected to the reaction chamber 11. During the process of switching the sealing cover 20 to the closed state, the second exhaust channel 21, which is sleeved on one end of the first exhaust channel 123, gradually approaches the circumferential outer wall of the bottom end of the first exhaust channel 123 until the sealing cover 20 is in the closed state. At this point, the second exhaust channel 21 is sleeved on the circumferential outer wall of the bottom end of the first exhaust channel 123, thereby ensuring the sealing effect between the first exhaust channel 123 and the second exhaust channel 21.

[0074] Specifically, the second exhaust passage 21 includes multiple first connecting sections 211 and one second connecting section 212. The first connecting sections 211 are disposed inside the sealing section 22, and the second connecting section 212 is disposed inside the extension section 23. The circumferential sidewall of the sealing section 22 has different exhaust ports corresponding to different first connecting sections 211. Furthermore, in this application, the diameter of the first connecting section 211 can be smaller than the diameter of the second connecting section 212. With this arrangement, the gas in the first exhaust passage 123 first enters the second connecting section 212 of the second exhaust passage 21, and then enters different first connecting sections 211 through the second connecting section 212, thereby ensuring that the gas in the second exhaust passage 21 is more easily discharged. Moreover, it is not difficult to see from the above that in this application, the end of the first connecting section 211 away from the second connecting section 212 is connected to the radial periphery of the sealing section 22. Therefore, in this application, the gas in the second exhaust passage 21 is discharged from the periphery of the sealing section 22.

[0075] Specifically, the inner circumferential wall of the silo 121 near the reaction chamber 11 has a cylindrical protrusion 1213. When the sealing cover 20 is closed, the side of the sealing section 22 facing the extension section 23 abuts against the top surface of the cylindrical protrusion 1213, and the circumferential sidewall of the sealing section 22 with the exhaust port abuts against the inner circumferential wall of the silo 121. Furthermore, the distance from the top surface of the cylindrical protrusion 1213 to the mounting opening 1212 is greater than the distance from the top surface of the first exhaust channel 123 to the mounting opening 1212.

[0076] In other words, in this embodiment, the cylindrical protrusion 1213 can be regarded as a hollow cylindrical tube disposed inside the silo 121, and the hollow cylindrical tube corresponding to the cylindrical protrusion 1213 is disposed in close contact with the inner wall of the silo 121, while the height of the cylindrical protrusion 1213 is less than the height of the silo 121. At this time, during the process of switching the sealing cover 20 to the closed state, the extension section 23 gradually extends into the interior of the cylindrical protrusion 1213 and compresses the gas inside the cylindrical protrusion 1213. When the sealing cover 20 is in the closed state, the extension section 23 of the sealing cover 20 can fill the space inside the cylindrical protrusion 1213 to achieve a seal. Meanwhile, the gas outlet of the first connecting section 211 of the second exhaust channel 21 is located above the cylindrical protrusion 1213 to ensure that the gas in the second exhaust channel 21 can be discharged smoothly. When the sealing cover 20 is installed in the closed state, the sealing section 22 of the sealing cover 20 abuts against the circumferential sidewall of the gas outlet of the second exhaust channel 21 and the circumferential sidewall of the silo 121 located above the cylindrical protrusion 1213, so as to achieve the technical effect of sealing the gas outlet of the second exhaust channel 21, thereby preventing gas from entering from the gas outlet of the second exhaust channel 21.

[0077] Therefore, in this application, the outer diameter of the sealing section 22 of the sealing cover 20 is approximately the same as the inner diameter of the silo 121, and the outer diameter of the extension section 23 is approximately the same as the inner diameter of the cylindrical protrusion 1213, so as to ensure the sealing effect of the sealing cover 20 on the silo 121 when it is in the closed state.

[0078] Furthermore, in this embodiment, when there are multiple reaction chambers 11 and only one first exhaust channel 123, the gas in the multiple reaction chambers 11 is discharged into the same first exhaust channel 123, so the multiple reaction chambers 11 are connected to the same first exhaust channel 123. Also, the end of the first exhaust channel 123 connected to the reaction chamber 11 can have multiple branch structures, and different branch structures are connected to different reaction chambers 11.

[0079] like Figures 6 to 9 As shown, in another specific embodiment of this application, unlike the above embodiment, the inner circumferential sidewall of the silo 121 near the reaction chamber 11 has a cylindrical protrusion 1213. A first exhaust channel 123 is disposed within the cylindrical protrusion 1213, and different first exhaust channels 123 communicate with at least one different reaction chamber 11. Therefore, in this embodiment, the external shape of the cylindrical protrusion 1213 is the same as in the above embodiment. The difference lies in that the number of first exhaust channels 123 can be the same as the number of reaction chambers 11, and the first exhaust channels 123 are disposed inside the cylindrical protrusion 1213, with the exhaust end of the first exhaust channel 123 located at the top of the cylindrical protrusion 1213. When the number of reaction chambers 11 and first exhaust channels 123 is the same, the reaction chambers 11 and first exhaust channels 123 correspond one-to-one, meaning different reaction chambers 11 communicate with different first exhaust channels 123. At this time, multiple first exhaust channels 123 are arranged circumferentially around the cylindrical protrusion 1213.

[0080] Specifically, at least a portion of the sealing cap 20 extends into the space enclosed by the cylindrical protrusion 1213 and abuts against the circumferential inner sidewall of the cylindrical protrusion 1213, and the sealing cap 20 has at least two stepped surfaces 24, with the periphery of the mounting opening 1212 and the top surface of the cylindrical protrusion 1213 abutting against different stepped surfaces 24 respectively.

[0081] It should also be noted that in this embodiment, the sealing cover 20 only serves a sealing function, or in other words, the first exhaust channel 123 is no longer connected to the interior of the sealing cover 20, and the sealing cover 20 no longer has an exhaust channel. Furthermore, when the sealing cover 20 is in the closed state, at least a portion of the sealing cover 20 extends into the interior of the cylindrical structure to seal the interior of the cylindrical structure. Simultaneously, one of the smaller diameter stepped surfaces 24 seals the top surface of the cylindrical protrusion 1213 to seal the exhaust port of the first exhaust channel 123, while the other larger diameter stepped surface 24 covers the top of the hopper 121 to seal the hopper 121.

[0082] Optionally, at least one of the cylindrical protrusion 1213 and the portion of the sealing cap 20 extending into the cylindrical protrusion 1213 is made of a flexible material. Preferably, the portion of the sealing cap 20 extending into the space enclosed by the cylindrical protrusion 1213 is made of rubber or silicone material, thereby ensuring that the sealing cap 20 can be more easily extended into the space enclosed by the cylindrical protrusion 1213 while also ensuring a sealing effect on the space enclosed by the cylindrical protrusion 1213.

[0083] Furthermore, in this embodiment, the metering groove 122 is disposed on the bottom surface of the card box body 10 within the space enclosed by the cylindrical protrusion 1213, or in other words, the projection of the metering groove 122 is located inside the cylindrical protrusion 1213.

[0084] In the two embodiments described above, the reaction chamber 11 includes a reaction chamber body 111, a first flow channel 112, and a second flow channel 113. The two ends of the first flow channel 112 are connected to the quantitative tank 122 and the reaction chamber body 111, respectively; the two ends of the second flow channel 113 are connected to the first exhaust channel 123 and the reaction chamber body 111, respectively. When the sealing cap 20 is pressed down, or when the sealing cap 20 extends into the sample loading chamber 12, the gas in the reaction chamber body 111 enters the first exhaust channel 123 through the second flow channel 113 and is discharged from the cartridge body 10.

[0085] Preferably, the first flow channel 112 includes at least two interconnected sections 1121, and a bubble filter chamber 1122 is disposed between the at least two interconnected sections 1121. Furthermore, in this application, the flow area of ​​the bubble filter chamber is larger than the flow area of ​​the interconnected sections 1121 of the first flow channel 112. When the test liquid flows from the first flow channel 112 to the reaction chamber body 111, the bubble filter chamber 1122 effectively filters the bubbles in the test liquid.

[0086] like Figures 10 to 15As shown, in another specific embodiment of this application, unlike the two embodiments described above, the cartridge body 10 also has at least one sample loading chamber 12. The sample loading chamber 12 includes a cylinder 121 and at least one metering groove 122. The cylinder 121 has a receiving cavity 1211 and an installation opening 1212 communicating with the receiving cavity 1211. When the sealing cover 20 is switched from the open state to the closed state, at least a portion of the sealing cover 20 extends into the receiving cavity 1211 through the installation opening 1212. The metering groove 122 is disposed in the receiving cavity 1211 and communicates with the reaction chamber 11.

[0087] Specifically, the card box body 10 includes a card box bottom plate 13 and a card box surrounding plate 14. The card box bottom plate 13 has a reaction chamber 11 and a sample loading chamber 12 is disposed on the card box bottom plate 13. The card box surrounding plate 14 is disposed around the periphery of the card box bottom plate 13 and has at least one exhaust opening 141.

[0088] Specifically, the detection cartridge also includes a semi-permeable membrane 40, and the reaction chamber 11 includes a reaction chamber body 111 and a first flow channel 112. The cartridge bottom plate 13 has an outlet 131 communicating with the reaction chamber body 111, and the semi-permeable membrane 40 at least covers the outlet 131; the two ends of the first flow channel 112 are respectively connected to the metering groove 122 and the reaction chamber body 111.

[0089] Furthermore, in this embodiment, when there are multiple reaction chambers 11, the multiple reaction chambers 11 can be arranged circumferentially around the chamber cylinder 121. At this time, the semipermeable membrane 40 can be designed as an annular shape, so that the reaction chamber body 111 of all the reaction chambers 11 can be covered by only one semipermeable membrane 40.

[0090] In other words, in this embodiment, the sample loading chamber 12 is only used to add the test solution and does not serve a venting function. When the test solution added to the sample loading chamber 12 enters the metering tank 122, it can enter the reaction chamber body 111 through the first flow channel 112 under its own gravity. Simultaneously, since the reaction chamber body 111 is covered by a semi-permeable membrane 40, the gas inside the reaction chamber body 111 can be discharged through the semi-permeable membrane 40. Therefore, in this embodiment, the function of the semi-permeable membrane 40 is to allow gas to pass through but not the test solution. Therefore, in this embodiment, it is not necessary to add a second flow channel 113 as in the previous embodiment. Furthermore, when the gas inside the reaction chamber body 111 passes through the semi-permeable membrane 40 and enters the space enclosed by the cartridge body and the cartridge enclosure 14, it can be discharged from the cartridge body 10 through the vent opening 141 of the cartridge enclosure 14. When the sealing cover 20 is switched to the closed state, the sealing cover 20 can cover the top of the card box enclosure 14 and seal the space enclosed by the card box enclosure 14 and the card box bottom plate 13, thereby ensuring the sealing effect of the test card box.

[0091] Furthermore, in this application, the semipermeable membrane 40 can be made of expanded polytetrafluoroethylene, or it can be a polyurethane microporous membrane. Of course, the semipermeable membrane 40 can also be supported by a composite reinforced material, or the semipermeable membrane 40 can be a polymer coated membrane.

[0092] Preferably, the first flow channel 112 includes at least two connected sections 1121, and a bubble filter chamber 1122 is provided between the at least two interconnected connected sections 1121.

[0093] Specifically, the sealing cover 20 is provided with a compression protrusion 25 corresponding to the receiving cavity 1211, and the sealing cover 20 is provided with a sealing enclosure 26 corresponding to the cartridge enclosure 14. When the sealing cover 20 is in the closed state, at least a portion of the compression protrusion 25 extends into the receiving cavity 1211 and seals the receiving cavity 1211, and at least a portion of the sealing enclosure 26 extends into the annular space enclosed by the cartridge enclosure 14 and seals the annular space and the exhaust opening 141. This arrangement ensures that during the process of switching the sealing cover 20 to the closed state, that is, during the process of the sealing cover 20 covering the cartridge enclosure 14, the compression protrusion 25 can compress the gas in the chamber 121, thereby facilitating the entry of the test liquid into the interior of the reaction chamber body 111. The sealing enclosure 26 can seal the exhaust opening 141 of the cartridge enclosure 14.

[0094] Optionally, at least the portion of the extrusion protrusion 25 corresponding to the bottom surface of the receiving cavity 1211 is made of a deformable material. For example, the extrusion protrusion 25 can be made of materials such as rubber or silicone. This arrangement ensures that the extrusion protrusion 25 can more easily enter the interior of the hopper 121.

[0095] Optionally, the sealing plate 26 is provided with a movable member 261 corresponding to the exhaust opening 141, at least a portion of which can enter or exit the sealing plate 26. With this arrangement, during the process of the sealing cover 20 switching to the closed state, the movable member 261 is first squeezed by the cartridge enclosure 14 and pushed into the interior of the sealing plate 26. As the sealing cover 20 continues to move, that is, as it continues to move axially along the cylindrical area enclosed by the cartridge enclosure 14, the position of the sealing plate 26 corresponding to the movable member 261 gradually aligns with the exhaust opening 141 on the cartridge enclosure 14. At this point, the movable member 261 is no longer squeezed by the cartridge enclosure 14, so it can exit the sealing plate 26 and enter the exhaust opening 141 under the reset action of the reset member or other structures within the sealing plate 26, thereby further sealing the opening and ensuring the sealing effect of the test cartridge.

[0096] Optionally, the cartridge enclosure 14 and the sealing enclosure 26 have mutually cooperating positioning structures 50. In this embodiment, the positioning structure 50 can be a positioning notch provided on the top of the enclosure and a positioning protrusion provided on the circumferential outer wall of the sealing enclosure 26 and extending radially. With this arrangement, during the process of the sealing cover 20 being placed on the cartridge body, the mutual cooperation of the positioning notch and the positioning protrusion makes it easier to accurately locate the sealing cover 20, thereby facilitating the alignment of the vent opening 141 and the movable part 261. At the same time, the cooperation of the positioning notch and the positioning protrusion also serves to indicate when the sealing cover 20 is in place.

[0097] In this application, regarding the relationship between the reaction chamber 11 and the metering tank 122, there are multiple reaction chambers 11 and multiple metering tanks 122, and each of the multiple reaction chambers 11 and multiple metering tanks 122 is connected in a one-to-one correspondence. Optionally, the multiple reaction chambers 11 are arranged at intervals around the bin 121. With this arrangement, when the test liquid enters the metering tank 122 from the bin 121, the test liquid can enter the different metering tanks 122 more evenly, thereby ensuring that the volume of test liquid entering different reaction chambers 11 is approximately the same, thus effectively ensuring the performance of the test cartridge. Of course, this arrangement also ensures that different metering tanks 122 can hold different test liquids and be detected through different reaction chambers 11.

[0098] Preferably, the volume of the metering tank 122 is larger than the volume of the reaction chamber 11. With this configuration, when injecting the test solution into the sample loading chamber 12, to ensure that multiple reaction chambers 11 can be filled with the test solution simultaneously, the metering tanks 122 can be filled with the test solution individually or until the test solution covers the surface of the metering tank 122, without the need to separately calculate the amount of test solution to be injected. In other words, once the metering tank 122 is filled with the test solution, the test solution in the metering tank 122 will definitely fill the corresponding reaction chamber 11.

[0099] Optionally, the test card holder also includes a sealing mold 30, which at least covers the bottom surface of the card holder body 10. This arrangement effectively ensures the sealing effect of the test card holder.

[0100] like Figures 17 to 20 As shown, in one specific embodiment of this application, and as... Figures 10 to 15Unlike the illustrated embodiment, the detection cartridge in this embodiment includes a cartridge body 10, a sealing cap 20, and a semi-permeable membrane 40. The cartridge body 10 has multiple reaction chambers 11 and at least one sample loading chamber 12, which is connected to the reaction chambers 11. The sealing cap 20 is closable on the cartridge body 10. When the sealing cap 20 is pressed down on the cartridge body 10, the test liquid can enter the reaction chambers 11 through the sample loading chamber 12. The cartridge body 10 also has an air outlet 131, which is connected to the reaction chambers 11, and the semi-permeable membrane 40 at least covers the air outlet 131.

[0101] When using the test cartridge of this application, since the cartridge body 10 has a reaction chamber 11, the test solution can enter the sample loading chamber 12 after being dripped into the cartridge body 10. Furthermore, after collecting the test solution, the sealing cap 20 is placed on the cartridge body 10. During the pressing of the sealing cap 20 against the cartridge body 10, the test solution can enter the reaction chamber 11 through the sample loading chamber 12. After the sealing cap 20 is closed, since the reaction chamber 11 is connected to the air outlet 131, the air in the reaction chamber 11 can be discharged outwards through the air outlet 131. Simultaneously, since the air outlet 131 is covered by a semi-permeable membrane 40, the semi-permeable membrane 40 can block the test solution in the reaction chamber 11, thereby preventing the test solution from escaping through the air outlet 131. Furthermore, after the sealing cap 20 is switched to the closed state, it seals the sample loading chamber 12 to prevent gas from entering the reaction chamber 11, thereby ensuring the preservation effect of the test solution and the accuracy of subsequent testing. Therefore, this application simplifies the structure of the test cartridge while maintaining its sealing effect. Thus, the test cartridge in this application effectively solves the problem of poor performance in existing test cartridges.

[0102] Optionally, the sealing cap 20 has an open state and a closed state. When the sealing cap 20 is in the open state, the test liquid can be added to the sample dispensing chamber 12. When the sealing cap 20 is in the closed state, the sealing cap 20 can seal at least a portion of the cartridge body 10. Furthermore, in this embodiment, the sealing cap 20 can be divided into a connecting portion and a cap body portion. The cap body portion can be threaded into the sample dispensing chamber 12, thereby enabling the cap body portion and the sample dispensing chamber 12 to switch between the open and closed states. The connecting portion ensures that even after the cap body portion is disengaged from the sample dispensing chamber 12 and switched to the open state, the sealing cap 20 can still maintain connection with the sample dispensing chamber 12 through the connecting portion. In this embodiment, the connecting portion can have an annular structure, and the connecting portion can be sleeved onto the sample dispensing chamber 12 through the annular structure.

[0103] In one specific embodiment of this application, the sealing cap 20 includes: a sealing cap body 27, which has an open state and a closed state, and when the sealing cap body 27 switches from the open state to the closed state, the sealing cap body 27 seals the sample dispensing chamber 12; and a sealing plug 28, which is movably disposed on the sealing cap body 27, and when the sealing cap body 27 switches from the closed state to the open state, the sealing plug 28 separates from the sealing cap body 27, and at least a portion of the sealing plug 28 is located inside the sample dispensing chamber 12. In other words, in this embodiment, the cover portion includes a sealing cover body 27 and a sealing plug 28. The sealing cover body 27 can be threaded into the outer wall of the sample loading chamber 12, ensuring that the sealing cover body 27 can be detachably connected to the sample loading chamber 12. That is, the sealing cover body 27 can switch between an open and closed state. Since the sealing plug 28 is movably disposed inside the cover body 27, when the sealing cover body 27 is switched to the closed state, the sealing plug 28 can directly enter or be squeezed into the sample loading chamber 12. Therefore, when the sealing cover body 27 is switched to the open state, the sealing plug 28 can continue to seal the sample loading chamber 12, preventing contamination or leakage of the liquid inside the test cartridge. Thus, in this application, when the sealing cover 20 is in the open state, the test liquid can be added to the sample loading chamber 12, and after addition, the sealing cover 20 can be switched to the closed state. Subsequently, if the sealing cap body 27 continues to be opened, the sealing plug 28 can also seal the sample loading chamber 12.

[0104] Therefore, in this application, the sealing plug 28 can be made of flexible and deformable materials such as silicone or rubber, and to ensure the sealing effect of the sealing plug 28, the sealing plug 28 and the sample loading chamber 12 can be an interference fit. Specifically, the reaction chamber 11 includes: a reaction chamber body 111, a cartridge bottom plate 13 having an outlet 131 communicating with the reaction chamber body 111, and a semi-permeable membrane 40 at least covering the outlet 131; a first flow channel 112, the two ends of which are respectively connected to the sample loading chamber 12 and the reaction chamber body 111. Furthermore, the reaction chamber 11 also includes a second flow channel 113, through which the reaction chamber body 111 communicates with the outlet 131. Of course, in this embodiment, a bubble filter chamber 1122 can also be provided on the first flow channel 112 as in other embodiments of this application.

[0105] Optionally, in the height direction, or in the thickness direction of the cartridge body 10, the communication position between the first flow channel 112 and the reaction chamber body 111 is located below the communication position between the second flow channel 113 and the reaction chamber body 111. With this arrangement, the test liquid and gas enter the internal opening of the reaction chamber body 111 through the first flow channel 112. Since the gas will be above the test liquid, placing the second flow channel 113 at the top of the reaction chamber body 111 allows the gas to exit the reaction chamber body 111 through the second flow channel 113, and also prevents the test liquid in the reaction chamber body 111 from entering the second flow channel 113.

[0106] Optionally, the second flow channel 113 includes a first exhaust section 1131, a second exhaust section 1132, and a third exhaust section 1133 connected in sequence. The end of the first exhaust section 1131 away from the second exhaust section 1132 is connected to the reaction chamber body 111, and the end of the third exhaust section 1133 away from the second exhaust section 1132 is connected to the exhaust port 131. In the height direction, the third exhaust section 1133 is located below the first exhaust section 1131. The first exhaust section 1131 and the third exhaust section 1133 extend horizontally, while the second exhaust section 1132 extends vertically. This arrangement allows for the rational use of the internal space of the card holder body 10, thereby avoiding excessive thickness of the card holder body 10 and facilitating the miniaturization design of the card holder body 10.

[0107] Optionally, the card box body 10 also has a third flow channel 114, all the first flow channels 112 are connected to the sample dispensing chamber 12 through the same third flow channel 114, and the third flow channel 114 has at least one bend 1141. Furthermore, when the sealing cap 20 is switched from the open state to the closed state, at least a portion of the sealing cap 20 extends into the sample loading chamber 12 and seals the sample loading chamber 12. The sample loading chamber 12 includes a cylinder 121 and at least one metering groove 122. The cylinder 121 has a receiving cavity 1211 and an installation opening 1212 communicating with the receiving cavity 1211. When the sealing cap 20 is switched from the open state to the closed state, at least a portion of the sealing cap 20 extends into the receiving cavity 1211 through the installation opening 1212. The metering groove 122 is disposed in the receiving cavity 1211. The metering groove 122 is funnel-shaped, with the top of the metering groove 122 being the large-diameter end and the bottom of the metering groove 122 being the small-diameter section. The bottom of the metering groove 122 has an opening communicating with the reaction chamber 11. Therefore, in this embodiment, the end of the third flow channel 114 away from the first flow channel 112 is connected to the small-diameter section of the metering groove 122. Furthermore, when the sealing cap 20 switches from the open state to the closed state, the air in the sample dispensing chamber 12 is compressed, which increases the pressure in the quantitative tank 122 and the third flow channel 114. This causes the test liquid to compress the inside of the cartridge body 10 and affect the sealing performance of the cartridge body 10. Therefore, in this embodiment, by providing a bending section 1141 on the third flow channel 114, the test liquid can be effectively buffered and the above problems can be solved.

[0108] Optionally, the cartridge body 10 includes a cartridge base plate 13, which has a reaction chamber 11 and an air outlet 131. A sample loading chamber 12 is disposed on the cartridge base plate 13, but unlike the previous embodiment, the sample loading chamber 12 is located near the periphery of the cartridge base plate 13. Further, optionally, multiple reaction chambers 11 are circumferentially spaced around the air outlet 131. In this application, the air outlet 131 is located near the center of the cartridge base plate 13 of the cartridge body 10. Further optionally, a groove is located at the center of the top surface of the cartridge base plate 13, and the opening on the top surface of the groove serves as the air outlet 131. The third exhaust section 1133 of the second flow channel 113 can communicate with the bottom of the groove. In this application, the connection point between the third flow channel 114 and all the first flow channels 112 is located below the groove, thus ensuring a more compact overall structure of the detection cartridge. Furthermore, in order to facilitate the connection between the third exhaust section 1133 of the second flow channel 113 and the settling tank, the end of the third exhaust section 1133 away from the second exhaust section 1132 may have a bent section, and the bent section may be parallel to the second exhaust section 1132.

[0109] Optionally, the detection cartridge also includes an upper sealing film 60, which covers the top of the cartridge base plate 13 of the cartridge body 10. A semi-permeable membrane 40 is located between the upper sealing film 60 and the cartridge base plate 13 of the cartridge body 10, and the upper sealing film 60 is provided with vent holes 61 corresponding to the semi-permeable membrane 40. Furthermore, in this application, the first exhaust section 1131 of the second flow channel 113 can communicate with the top surface of the cartridge base plate 13 and be sealed by the upper sealing film 60. Alternatively, the first exhaust section 1131 can be regarded as an opening groove with an opening facing the top surface of the cartridge base plate 13, and a flow channel structure is formed by the sealing effect of the upper sealing film 60.

[0110] Optionally, the detection card holder also includes a lower sealing film 70, which covers the bottom surface of the card holder base plate 13 of the card holder body 10. Furthermore, in this application, at least a portion of the first flow channel 112 can communicate with the bottom surface of the card holder base plate 13 and be sealed by the lower sealing film 70. Alternatively, the first flow channel 112 can be considered as an opening groove facing the bottom surface of the card holder base plate 13, forming a flow channel structure through the sealing effect of the lower sealing film 70. Of course, for the third exhaust section 1133 of the second flow channel 113, when the third exhaust section 1133 is offset from the first flow channel 112 in the thickness direction of the card holder body 10, the positional relationship and arrangement of the third exhaust section 1133, the third flow channel 114, the bottom surface of the card holder base plate 13 of the card holder body 10, and the lower sealing film 70 can be the same as those of the first flow channel 112. The special design of the first flow channel 112 and the first exhaust section 1131 corresponding to the top and bottom surfaces of the card box base plate 13 can effectively reduce the overall thickness of the card box base plate 13, thereby facilitating the miniaturization design of the detection card box.

[0111] It should be noted that, as Figure 16 As shown, for the detection cartridge in this application, the reaction chamber 11 further includes a first refractive cavity 15 and a second refractive cavity 16 symmetrically arranged about the reaction chamber body 111. The first refractive cavity 15 has a first refractive surface 151 corresponding to the reaction chamber body 111, and the second refractive cavity 16 has a second refractive surface 161 corresponding to the reaction chamber body 111. With this arrangement, when the reaction chamber body 111 is filled with the test liquid, when detecting the test liquid in the reaction chamber body 111, the detection light source can shine from the bottom or top of the detection cartridge toward the inside of the first refractive cavity 15, and the detection light source can be refracted into the inside of the reaction chamber body 111 through the first refractive surface 151, thereby illuminating the test liquid in the reaction chamber body 111. At this time, the fluorescence generated by the test liquid being irradiated can be refracted through the second refractive surface 161 to the receiver at the bottom or top of the second refractive cavity 16, thereby realizing the detection of the test liquid.

[0112] As can be seen from the above description, the embodiments of this utility model achieve the following technical effects:

[0113] 1. Effectively solves the problem of poor performance of detection card boxes in existing technologies;

[0114] 2. Simple structure and stable performance.

[0115] Obviously, the embodiments described above are only some embodiments of this utility model, and not all embodiments. Based on the embodiments of this utility model, all other embodiments obtained by those skilled in the art without creative effort should fall within the protection scope of this utility model.

[0116] It should be noted that the terminology used herein is for the purpose of describing particular embodiments only and is not intended to limit the exemplary embodiments according to this application. As used herein, the singular form is intended to include the plural form as well, unless the context clearly indicates otherwise. Furthermore, it should be understood that when the terms "comprising" and / or "including" are used in this specification, they indicate the presence of features, steps, operations, devices, components, and / or combinations thereof.

[0117] It should be noted that the terms "first," "second," etc., used in the specification, claims, and accompanying drawings of this application are used to distinguish similar objects and are not necessarily used to describe a specific order or sequence. It should be understood that such data can be interchanged where appropriate so that the embodiments of this application described herein can be implemented in sequences other than those illustrated or described herein.

[0118] The above description is merely a preferred embodiment of this utility model and is not intended to limit the utility model. Various modifications and variations can be made to this utility model by those skilled in the art. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of this utility model should be included within the protection scope of this utility model.

Claims

1. A test cartridge, characterized by, include: The cartridge body (10) has multiple reaction chambers (11) and at least one sample dispensing chamber (12), the sample dispensing chamber (12) being connected to the reaction chambers (11); A sealing cap (20) is provided on the cartridge body (10) in an openable and closable manner. When the sealing cap (20) is pressed down on the cartridge body (10), the test liquid can enter the reaction chamber (11) through the sample loading chamber (12). The sealing cap (20) has an open state and a closed state. When the sealing cap (20) is in the open state, the test liquid can be added to the sample loading chamber (12). When the sealing cap (20) is in the closed state, the sealing cap (20) can seal at least a portion of the cartridge body (10).

2. The test cartridge of claim 1, wherein, When the sealing cap (20) switches from the open state to the closed state, at least a portion of the sealing cap (20) extends into the sample dispensing chamber (12) and seals the sample dispensing chamber (12), the sample dispensing chamber (12) comprising: A silo (121) having a receiving cavity (1211) and an installation opening (1212) communicating with the receiving cavity (1211), wherein when the sealing cover (20) is switched from the open state to the closed state, at least a portion of the sealing cover (20) extends into the receiving cavity (1211) through the installation opening (1212); At least one metering groove (122) is provided, at least a portion of which is disposed on the bottom surface of the receiving cavity (1211) and the metering groove (122) is in communication with the reaction cavity (11).

3. The test cartridge of claim 2, wherein, The gas in the reaction chamber (11) can be discharged from the cartridge body (10) through the sample dispensing chamber (12), and the sample dispensing chamber (12) further includes: At least one first exhaust channel (123) is disposed in the receiving cavity (1211), and the reaction cavity (11) is connected to the metering tank (122) and the first exhaust channel (123) respectively.

4. The test cartridge of claim 3, wherein, The sealing cover (20) has a second exhaust channel (21). When the sealing cover (20) is in the closed state, one end of the second exhaust channel (21) is sleeved on the end of the first exhaust channel (123) away from the reaction chamber (11) and communicates with the first exhaust channel (123).

5. The detection card holder according to claim 4, characterized in that, When the sealing cap (20) is in the closed state, the hopper (121) seals the other end of the second exhaust passage (21).

6. The test cartridge of claim 4, wherein, The sealing cap (20) includes a sealing section (22) and an extension section (23) disposed on the sealing section (22) toward the first exhaust passage (123). At least a portion of the second exhaust passage (21) is located on the sealing section (22), and at least another portion of the second exhaust passage (21) is located on the extension section (23). One end of the first exhaust passage (123) away from the reaction chamber (11) can enter or exit the extension section (23).

7. The test cartridge of claim 6, wherein, The second exhaust passage (21) includes a plurality of first connecting sections (211) and a second connecting section (212). The first connecting sections (211) are disposed inside the sealing section (22), and the second connecting section (212) is disposed inside the extension section (23). The circumferential sidewall of the sealing section (22) is provided with different exhaust ports corresponding to different first connecting sections (211).

8. The test cartridge of claim 7, wherein, The inner circumferential wall of the silo (121) near the reaction chamber (11) has a cylindrical protrusion (1213). When the sealing cover (20) is in the closed state, the sealing section (22) facing the extension section (23) abuts against the top surface of the cylindrical protrusion (1213), and the circumferential wall of the sealing section (22) with the exhaust port abuts against the inner circumferential wall of the silo (121).

9. The detection card holder according to claim 3, characterized in that, The inner circumferential wall of the silo (121) near the reaction chamber (11) has a cylindrical protrusion (1213), and the first exhaust channel (123) is disposed in the cylindrical protrusion (1213). Different first exhaust channels (123) are respectively connected to at least one different reaction chamber (11).

10. The detection card holder according to claim 9, characterized in that, At least a portion of the sealing cap (20) extends into the space enclosed by the cylindrical protrusion (1213) and abuts against the circumferential inner sidewall of the cylindrical protrusion (1213), and the sealing cap (20) has at least two stepped surfaces (24), with the periphery of the mounting opening (1212) and the top surface of the cylindrical protrusion (1213) abutting against different stepped surfaces (24).

11. The test cartridge of claim 3, wherein, The reaction chamber (11) includes: The reaction chamber body (111); The first flow channel (112) is connected at both ends to the metering tank (122) and the reaction chamber body (111), respectively. The second flow channel (113) is connected at both ends to the first exhaust channel (123) and the reaction chamber body (111), respectively. When the sealing cover (20) is pressed down, the gas in the reaction chamber body (111) enters the first exhaust channel (123) through the second flow channel (113) and is discharged from the card box body (10).

12. The test cartridge of claim 11, wherein, The first flow channel (112) includes at least two connected sections (1121), and a bubble filter chamber (1122) is provided between the at least two interconnected connected sections (1121).

13. The test cartridge of claim 2, wherein, The card box body (10) includes: Card box bottom plate (13), the card box bottom plate (13) has the reaction chamber (11), and the sample dispensing chamber (12) is disposed on the card box bottom plate (13).

14. The detection card holder according to claim 13, characterized in that, The card box body (10) includes: Card holder enclosure (14) is provided around the periphery of the card holder bottom plate (13), and the card holder enclosure (14) has at least one vent opening (141).

15. The detection card holder according to claim 13, characterized in that, The detection cartridge further includes a semi-permeable membrane (40), and the reaction chamber (11) includes: The reaction chamber body (111) has an outlet (131) communicating with the reaction chamber body (111), and the semi-permeable membrane (40) at least covers the outlet (131). The first flow channel (112) is connected at both ends to the metering tank (122) and the reaction chamber body (111), respectively.

16. The test cartridge of claim 15, wherein, The first flow channel (112) includes at least two connected sections (1121), and a bubble filter chamber (1122) is provided between the at least two interconnected connected sections (1121).

17. The detection card holder according to claim 14, characterized in that, The sealing cover (20) is provided with a compression protrusion (25) corresponding to the receiving cavity (1211), and the sealing cover (20) is provided with a sealing plate (26) corresponding to the card holder surrounding plate (14). When the sealing cover (20) is in the closed state, at least a portion of the compression protrusion (25) extends into the receiving cavity (1211) and seals the receiving cavity (1211), and at least a portion of the sealing plate (26) extends into the annular space enclosed by the card holder surrounding plate (14) and seals the annular space and the exhaust opening (141).

18. The test cartridge of claim 15, wherein, The reaction chamber (11) further includes a second flow channel (113), and the reaction chamber body (111) is connected to the air outlet (131) through the second flow channel (113).

19. The test cartridge of claim 18, wherein, In the height direction, the communication position between the first flow channel (112) and the reaction chamber body (111) is located below the communication position between the second flow channel (113) and the reaction chamber body (111).

20. The detection card holder according to claim 18, characterized in that, The second flow channel (113) includes a first exhaust section (1131), a second exhaust section (1132), and a third exhaust section (1133) connected in sequence. The end of the first exhaust section (1131) away from the second exhaust section (1132) is connected to the reaction chamber body (111), and the end of the third exhaust section (1133) away from the second exhaust section (1132) is connected to the exhaust port (131). In the vertical direction, the third exhaust section (1133) is located below the first exhaust section (1131); and / or The first exhaust section (1131) and the third exhaust section (1133) extend in a horizontal direction; and / or The second exhaust section (1132) extends in the vertical direction.

21. The test cartridge of claim 15, wherein, The card box body (10) also has a third flow channel (114), all the first flow channels (112) are connected to the sample loading chamber (12) through the same third flow channel (114), and the third flow channel (114) has at least one bend (1141).

22. The detection card holder according to any one of claims 18 to 21, characterized in that, The detection cartridge also includes: An upper sealing film (60) is provided, which covers the top of the card holder bottom plate (13). A semi-permeable membrane (40) is located between the upper sealing film (60) and the card holder bottom plate (13), and the upper sealing film (60) is provided with vent holes (61) corresponding to the semi-permeable membrane (40); and / or A lower sealing film (70) is provided on the bottom surface of the card holder bottom plate (13).

23. The test cartridge of any one of claims 18-21, wherein, The plurality of reaction chambers (11) are arranged circumferentially around the gas outlet (131).

24. The detection card holder according to any one of claims 18 to 21, characterized in that, The sealing cap (20) includes: The sealing cap body (27) has an open state and a closed state. When the sealing cap body (27) switches from the open state to the closed state, the sealing cap body (27) seals the sample dispensing chamber (12). A sealing plug (28) is movably disposed on the sealing cap body (27). When the sealing cap body (27) switches from the closed state to the open state, the sealing plug (28) separates from the sealing cap body (27), and at least a portion of the sealing plug (28) is located in the sample dispensing chamber (12).

25. The detection card holder according to claim 11 or 15, characterized in that, The reaction chamber (11) further includes a first refractive cavity (15) and a second refractive cavity (16) disposed on both sides of the reaction chamber body (111). The first refractive cavity (15) has a first refractive surface (151) corresponding to the reaction chamber body (111), and the second refractive cavity (16) has a second refractive surface (161) corresponding to the reaction chamber body (111).

26. The detection card holder according to any one of claims 2 to 16, characterized in that, There are multiple metering tanks (122), and the multiple reaction chambers (11) and the multiple metering tanks (122) are connected in a one-to-one correspondence; and / or The plurality of said reaction chambers (11) are arranged at intervals around the bin (121); and / or The volume of the metering tank (122) is greater than the volume of the reaction chamber (11).

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