A dynamic incubation device

CN224772722UActive Publication Date: 2026-09-18XIAMEN TALENT BIOMEDICAL TECH CO LTD
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Patent Information

Application Number
CN202422458255.4
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-10-11
Publication Date
2026-09-18
Estimated Expiration
2034-10-11

AI Technical Summary

Technical Problem

[0005]本实用新型的目的在于提供一种动态孵育装置,直接将载片固定在侧板上,至少在一定程度上克服由于相关技术中将载片由底板支撑,底板发生形变后,会导致载片与盖板不能很好贴合,影响检测效果的问题

Benefits of technology

[0017] As can be seen from the above technical solution, the advantages and positive effects of the dynamic incubation device of this utility model are as follows:

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Abstract

The utility model provides a kind of dynamic incubation device, can load slide, including cover plate and support assembly, the support assembly includes a pair of side plates and a pair of pushers, a pair of the pusher is respectively slidably connected with a pair of the side plate, and respectively with the both sides of the cover plate is connected;A pair of the side plate is equipped with fixing piece and support piece, the fixing piece is used to load and fix the slide, the support piece is used to support the bottom of the slide, and limit the slide from the bottom of the side plate and slide out;Wherein, the slide can be supported between a pair of the fixing piece;Pusher is slid under the drive of external force, force the cover plate relative to the slide and do open-close movement, to mix the reagent between the cover plate and the slide.
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Description

Technical Field

[0001] This utility model relates to the field of biological detection device technology, and in particular to a dynamic incubation device. Background Technology

[0002] Currently, staining and detection methods for slide specimens are generally divided into static incubation and dynamic incubation. Static incubation involves adding reagents to the slide specimen and allowing it to stand for a certain period of time before proceeding to the next step. Dynamic incubation involves adding reagents to the slide specimen, stirring and mixing the reagents and specimen before proceeding to the next step. Generally, staining or detection using dynamic incubation is more efficient than static incubation.

[0003] In related technologies, dynamic incubation devices are generally equipped with supports, with a cover plate and a base plate for loading slides between the supports. The cover plate can move relative to the base plate. However, due to unreasonable structural design between the base plate and the supports, the base plate spanning between the supports is prone to deformation after prolonged use under the influence of high temperature, corrosive liquids, and extrusion pressure. The relative position of the slides loaded on the base plate will also change, which will lead to poor adhesion between the cover plate and the slides, as well as uneven heating, affecting the detection results.

[0004] It should be noted that the information disclosed in the background section above is only used to enhance the understanding of the background of this utility model, and therefore may include information that does not constitute prior art known to those skilled in the art. Utility Model Content

[0005] The purpose of this invention is to provide a dynamic incubation device that directly fixes the slide onto the side plate, thereby overcoming, to some extent, the problem that in related technologies, where the slide is supported by a base plate, deformation of the base plate can lead to poor adhesion between the slide and the cover plate, affecting the detection effect.

[0006] Other features and advantages of this invention will become apparent from the following detailed description, or may be learned in part by practice of this disclosure.

[0007] According to one aspect of the present invention, a dynamic incubation device is provided, capable of loading a carrier plate, including a cover plate and a support assembly. The support assembly includes a pair of side plates and a pair of pushers, the pair of pushers being slidably connected to the pair of side plates and respectively connected to both sides of the cover plate. Each pair of side plates is provided with a fixing member and a support member. The fixing member is used to load and fix the carrier plate, and the support member is used to support the bottom of the carrier plate and restrict the carrier plate from sliding out from the bottom of the side plate. The carrier plate can be supported between the pair of fixing members. The pushers slide under the drive of an external force, forcing the cover plate to open and close relative to the carrier plate.

[0008] According to one embodiment of the present invention, the fixing member is a slot, and the slot is disposed on the side plate.

[0009] According to one embodiment of the present invention, the side plate is provided with a first fixing plate and a second fixing plate, and a slot is formed between the first fixing plate and the second fixing plate.

[0010] According to one embodiment of the present invention, the second fixing plate is located above the first fixing plate, and the top of the second fixing plate is provided with a guide surface, which is used to guide the carrier piece to be inserted into the slot.

[0011] According to one embodiment of the present invention, the first fixing plate and the second fixing plate are disposed on the top of the side plate, and the support member is disposed on the bottom of the side plate; a first support plate is disposed in the middle of the side plate, and the first support plate is used to support the middle of the carrier sheet.

[0012] According to one embodiment of the present invention, the first fixing plate, the second fixing plate, the first support plate and the support member are respectively integrally formed with the side plate or separately formed.

[0013] According to one embodiment of the present invention, the support member includes a second support plate and a limiting block. The second support plate is used to support the bottom of the carrier sheet, and the limiting block is used to abut the bottom end of the carrier sheet; or, the support member is a step that extends inward from the bottom of the side plate and protrudes.

[0014] According to one embodiment of the present invention, the cover plate has outwardly extending protrusions on both sides, the pusher has a groove supporting the protrusions, the top of the groove has a slot opening, and the protrusions can enter and exit the slot opening.

[0015] According to one embodiment of the present invention, the bottom of the cover plate is provided with a liquid guiding portion, which extends downward from the bottom surface of the cover plate and converges; and / or the top of the cover plate is provided with a support portion, which can abut against the downstream fixing member to separate the cover plate from the carrier.

[0016] According to one embodiment of the present invention, the bracket assembly includes multiple pairs of side plates and multiple pairs of pushing members, the multiple pairs of pushing members being slidably connected to the multiple pairs of side plates respectively, and two adjacent side plates forming a connecting plate.

[0017] As can be seen from the above technical solution, the advantages and positive effects of the dynamic incubation device of this utility model are as follows:

[0018] The dynamic incubation device provided by this utility model comprises a pair of pushers slidably connected to a pair of side plates, and the pushers are respectively connected to both sides of a cover plate. Each pair of side plates is provided with a fixing member and a support member. The fixing member is used to load and fix the carrier, and the support member is used to support the bottom of the carrier and prevent the carrier from sliding out from the bottom of the side plate. The carrier can be directly supported on the pair of fixing members, and the bottom of the carrier is supported by the support member. This structure is simple and less prone to deformation compared to a base plate spanning between the pair of side plates, allowing the gap between the carrier and the cover plate to remain relatively stable and the heating to be more uniform. Furthermore, the pushers slide under external force, forcing the cover plate to open and close relative to the carrier, thus mixing the reagent between the cover plate and the carrier. At the same time, the absence of a base plate avoids the deformation of the base plate affecting the accuracy of the fit between the cover plate and the carrier.

[0019] Furthermore, the support assembly is provided with multiple pairs of side plates and multiple pairs of pushers. The multiple pairs of pushers are slidably connected to the multiple pairs of side plates, and two adjacent side plates form a connecting plate. This can form multiple rows of linkage incubation units, each row working independently, enabling batch incubation of slide specimens.

[0020] It should be understood that the above general description and the following detailed description are exemplary and explanatory only, and are not intended to limit this disclosure. Attached Figure Description

[0021] The above and other features and advantages of this invention will become more apparent from a detailed description of exemplary embodiments with reference to the accompanying drawings.

[0022] Figure 1 A schematic diagram of the structure of a dynamic incubation device according to an embodiment of the present disclosure is shown.

[0023] Figure 2 A schematic diagram of the side plate structure is shown in an embodiment of this disclosure.

[0024] Figure 3 A cross-sectional structural schematic diagram of the dynamic incubation device in an embodiment of this disclosure is shown.

[0025] Figure 4 A schematic diagram of the structure of a cover plate according to an embodiment of the present disclosure is shown.

[0026] Figure 5 A schematic diagram of the structure of another cover plate in an embodiment of this disclosure is shown.

[0027] Figure 6 A schematic diagram of the structure of another cover plate in an embodiment of this disclosure is shown.

[0028] Figure 7 A schematic diagram of the side plate and corresponding pusher component in an embodiment of this disclosure is shown.

[0029] Figure 8 A schematic diagram of another dynamic incubation device in an embodiment of this disclosure is shown.

[0030] Figure 9 A schematic diagram of the structure of a side plate according to an embodiment of the present disclosure is shown.

[0031] Figure 10 A schematic diagram of another side plate in an embodiment of this disclosure is shown.

[0032] Figure 11 A schematic diagram of the structure of a support member according to an embodiment of the present disclosure is shown.

[0033] The reference numerals in the attached figures are explained as follows:

[0034] 10. Slide carrier;

[0035] 20. Cover plate; 21. Protrusion; 22. Liquid guiding part; 23. Flow guiding surface; 24. Support part;

[0036] 30. Side plate; 31. Slot; 32. First fixing plate; 33. Second fixing plate; 34. First support plate; 35. Support component; 36. Second support plate; 37. Limiting block; 38. Guide surface; 39. Guide groove; 40. Limiting groove; 41. Sliding groove; 42. First side plate; 43. Second side plate; 44. Third side plate; 45. Fourth side plate;

[0037] 50. Pushing element; 51. Groove; 52. Slot opening; 53. First pair of pushing elements; 54. Second pair of pushing elements;

[0038] A. First direction. Detailed Implementation

[0039] Exemplary embodiments will now be described more fully with reference to the accompanying drawings. However, these exemplary embodiments can be implemented in many forms and should not be construed as limited to the embodiments set forth herein; rather, these embodiments are provided so that the present invention will be thorough and complete, and will fully convey the concept of the exemplary embodiments to those skilled in the art. The same reference numerals in the drawings denote the same or similar structures, and therefore their detailed description will be omitted.

[0040] refer to Figures 1 to 3This embodiment provides a dynamic incubation device capable of loading a slide 10. The device includes a cover plate 20 and a support assembly. The support assembly includes a pair of side plates 30 and a pair of pushers 50. The pair of pushers 50 are slidably connected to the pair of side plates 30 and connected to both sides of the cover plate 20. Each pair of side plates 30 is provided with a fixing member and a support member 35. The fixing member is used to load and fix the slide 10, and the support member 35 is used to support the bottom of the slide 10 and restrict the slide 10 from sliding out from the bottom of the side plate 30. The slide 10 can be supported between the pair of fixing members, and the pushers 50 can slide in a first direction A under the drive of an external force, forcing the cover plate 20 to open and close relative to the slide 10 to mix the reagent between the cover plate 20 and the slide 10.

[0041] In this embodiment, the carrier plate 10 can be directly supported on a pair of fixing members, and the bottom of the carrier plate 10 is supported by the support member 35. This structure is simple and stable, and can keep the gap between the carrier plate 10 and the cover plate 20 stable and reliable. This avoids the situation of a base plate that is laid horizontally between a pair of side plates 30, which is prone to deformation (in the background art, the base plate is laid horizontally between a pair of side plates 30, with the two sides of the base plate connected to a pair of side plates 30 respectively, but the middle of the base plate is not supported. After a long period of use, due to temperature, liquid corrosion, and the compression of the cover plate 20 and the carrier plate 10, the base plate is prone to deformation).

[0042] A pair of side plates 30 are arranged symmetrically to each other, and a connecting rod and a connecting plate can be provided between them to fix the pair of side plates 30 together.

[0043] The fixing element can be a slot 31, which is set on the side plate 30. The top of the side plate 30 is provided with a first fixing plate 32 and a second fixing plate 33. The upper surface of the first fixing plate 32 and the lower surface of the second fixing plate 33 are parallel to each other, and the gap between them is the slot 31. The width of the slot 31 is adapted to the thickness of the slide 10. The spacing between two adjacent slots 31 is equal. The first fixing plate 32 and the second fixing plate 33 are both set at a certain angle to the horizontal plane, so that the slot 31 is inclined. After the slide 10 is inserted into the slot 31, it is at a certain angle to the horizontal plane. This can save space and load more slides 10 specimens.

[0044] The second fixing plate 33 is located above the first fixing plate 32. The top of the second fixing plate 33 is provided with a guide surface 38, which is set at an angle to the lower surface of the second fixing plate 33. When the carrier 10 is inserted into the slot 31, the guide surface 38 can guide the carrier 10, so that the carrier 10 can be inserted into the slot 31 more smoothly.

[0045] The first fixing plate 32 and the second fixing plate 33 are arranged on the top of the side plate 30, the first supporting plate 34 is arranged in the middle of the side plate 30, and the supporting member 35 is arranged at the bottom of the side plate 30. The first fixing plate 32, the second fixing plate 33, the first supporting plate 34 and the supporting member 35 can all be manufactured by an integral molding process with the side plate 30. Wherein, the lower surface of the first fixing plate 32 is provided with a downwardly protruding convex block, and the convex block can enhance the rigidity of the first fixing plate 32. It should be noted that the first fixing plate 32, the second fixing plate 33, the first supporting plate 34 and the supporting member 35 can also be separately molded from the side plate 30 respectively.

[0046] In an example, as shown in Figure 2 and Figure 9 , the supporting member 35 comprises a second supporting plate 36 and a limiting block 37, the second supporting plate 36 can be arranged perpendicularly (or crosswise) to the limiting block 37, the second supporting plate 36 is used for supporting the bottom of the slide 10, and the limiting block 37 is used for abutting against the bottom end of the slide 10. The first fixing plate 32 is used for supporting the top of the slide 10, the first supporting plate 34 is used for supporting the middle part of the slide 10, and the second supporting plate 36 is used for supporting the bottom of the slide 10.

[0047] The slide 10 can be supported between a pair of side plates 30 under the cooperation of the first fixing plate 32, the first supporting plate 34 and the second supporting plate 36, and the slide 10 is arranged at a certain angle with the horizontal plane. The upper surface of the first fixing plate 32, the upper surface of the first supporting plate 34 and the upper surface of the second supporting plate 36 are all located on the same plane.

[0048] In another example, as shown in Figure 10 and Figure 11 , the supporting member 35 is arranged at the bottom of the side plate 30, the supporting member 35 and the side plate 30 are integrally formed, the supporting member 35 can be a step extending inward and protruding from the bottom of the side plate 30, and the bottom of the slide 10 can be supported on the convex platform.

[0049] Referring to Figures 1 to 8 , the top side surface of the cover plate 20 is provided with an outwardly extending protrusion 21, the pushing member 50 is provided with grooves 51 for supporting the protrusions 21, and the spacing between two adjacent grooves 51 is equal. A groove opening 52 is opened on the top surface of the groove 51, and the protrusion 21 can enter and exit through the groove opening 52.

[0050] The protrusions 21 on both sides of one cover plate 20 are respectively connected to a pair of pushing members 50, and the protrusions 21 are supported in the grooves 51. When the pushing member 50 is driven by an external force to reciprocate along the first direction A, the bottom of the cover plate 20 abuts against the slide 10, and the top of the cover plate 20 is pushed by the pushing member 50, forcing the top of the cover plate 20 to move away from and close to the slide 10, which can stir and mix the reagent and specimen between the slide 10 and the cover plate 20, accelerating the reaction.

[0051] like Figure 4 and Figure 5 As shown, in one example, a support portion 24 is provided on the top of the cover plate 20. The support portion 24 is a protrusion that protrudes upward from the top surface of the cover plate 20. Two support portions 24 can be provided on one cover plate 20, and the two support portions 24 are located at the two ends of the top edge of the cover plate 20, respectively. When the pusher 50 moves in the first direction A, the cover plate 20 gradually separates from the carrier plate 10 until the protrusion 21 on the cover plate 20 reaches the pressed state. At this time, the support portion 24 will abut against the lower surface of the downstream first fixing plate 32. The protrusion 21 of the cover plate 20 is subjected to a rightward force applied by the pusher 50, and the support portion 24 is subjected to a downward oblique force applied by the downstream first fixing plate 32, causing the bottom end of the cover plate 20 to lift up and the cover plate 20 to separate from the carrier plate 10.

[0052] like Figure 5 As shown, in one example, the bottom of the cover plate 20 is provided with a liquid guiding part 22, which extends downward from the bottom surface of the cover plate 20 and converges to form a triangle. A flow guiding surface 23 is provided on the liquid guiding part 22, which is an inverted triangle with a pointed bottom. When it is necessary to replace the cover plate 20 or to drain the liquid between the cover plate 20 and the carrier plate 10, the cover plate 20 and the carrier plate 10 switch from an attached state to a detached state. The liquid on the cover plate 20 can flow downward to the flow guiding surface 23 and out from the bottom end of the flow guiding surface 23, thus draining the accumulated liquid from the cover plate 20.

[0053] A groove 41 along the first direction A is provided on the side plate 30, and the pusher 50 can slide in the groove 41 along the first direction A. A connecting member can be provided between a pair of pushers 50, and by driving the connecting member, the pair of pushers 50 can reciprocate synchronously along the first direction A.

[0054] A limiting groove 40 and a guide groove 39 are also provided on the side plate 30. The distance between two adjacent limiting grooves 40 is equal, and the distance between two adjacent guide grooves 39 is equal. The protrusion 21 is located in both the groove 51 and the limiting groove 40. The limiting groove 40 is used to limit the movement distance of the protrusion 21. When the pusher 50 slides to a specific position in the slide groove 41, the guide groove 39 and the groove 51 can communicate. At this time, the protrusion 21 can enter and exit the guide groove 39 and the groove 51, which facilitates the replacement of the damaged cover plate 20.

[0055] like Figures 1 to 3As shown, when the pusher 50 reciprocates in the first direction A, the protrusion 21 is supported and pushed by the groove 51, but the protrusion 21 is also restricted by the limiting groove 40. Therefore, when the pusher 50 moves to the right, it forces the protrusion 21 in the groove 51 to move obliquely upward along the bottom of the limiting groove 40, so that the top of the cover plate 20 moves away from the carrier plate 10, and the top of the cover plate 20 and the top of the carrier plate 10 form an opening. Conversely, when the pusher 50 moves to the left, it forces the protrusion 21 in the groove 51 to move obliquely downward along the top of the limiting groove 40, that is, the top of the cover plate 20 gradually approaches the carrier plate 10, the opening between the top of the cover plate 20 and the top of the carrier plate 10 becomes smaller, until the cover plate 20 and the carrier plate 10 are in contact, and a capillary gap is formed between the cover plates 20 and the carrier plate 10. In this way, under the reciprocating motion of the pusher 50, the cover plate 20 opens and closes relative to the carrier plate 10 to mix the reagent. It should be noted that the movement of the cover plate 20 relative to the carrier plate 10 by the pusher 50 is existing technology and will not be described in detail here.

[0056] refer to Figures 1 to 9 The support assembly may include multiple pairs of side plates 30 and multiple pairs of pushers 50. The multiple pairs of pushers 50 are slidably connected to the multiple pairs of side plates 30, and two adjacent side plates 30 form a connecting plate. Multiple cover plates 20 are connected to the support assembly. Among them, one cover plate 20 corresponds to one carrier plate 10.

[0057] For example, the support assembly may include a first pair of side plates, a second pair of side plates, a first pair of pushers 53, and a second pair of pushers 54. Multiple cover plates 20 can be provided between the first pair of side plates and the second pair of side plates. This can form a double-row, independently operating, interconnected incubation unit. The first pair of side plates includes a first side plate 42 and a second side plate 43, and the second pair of side plates includes a third side plate 44 and a fourth side plate 45. The second side plate 43 and the third side plate 44 can be manufactured using a one-piece molding process, or they can be connected back-to-back by locking fasteners. The first side plate 42 and the second side plate 43 are symmetrically arranged, meaning that the slots 31, support members 35, limiting grooves 40, and guide grooves 39 on the first side plate 42 and the second side plate 43 are all correspondingly arranged. The third side plate 44 and the fourth side plate 45 are also symmetrically arranged.

[0058] The first pair of pushers 53 are slidably connected to the first pair of side plates, and the second pair of pushers 54 are slidably connected to the second pair of side plates. Multiple cover plates 20 can be connected between the first pair of pushers 53 and between the second pair of pushers 54, wherein the first pair of pushers 53 and the second pair of pushers 54 work independently of each other.

[0059] Although the support assembly in the above embodiments includes a first pair of side plates, a second pair of side plates, a first pair of pushers 53, and a second pair of pushers 54, the present invention is not limited thereto. For example, the support assembly may include a first pair of side plates, a second pair of side plates, a third pair of side plates, a first pair of pushers 53, a second pair of pushers 54, and a third pair of pushers, thus forming three rows of interconnected incubation units, each row operating independently. It should be noted that the number of pairs of side plates 30 and pushers 50 is the same, and the quantity can be determined according to the actual application.

[0060] In the embodiments of the utility model, the terms "first," "second," and "third" are used for descriptive purposes only and should not be construed as indicating or implying relative importance; the term "multiple" refers to two or more unless otherwise explicitly defined. The terms "install," "connect," "join," and "fix" should be interpreted broadly. For example, "connect" can be a fixed connection, a detachable connection, or an integral connection; "join" can be a direct connection or an indirect connection through an intermediate medium. Those skilled in the art can understand the specific meaning of the above terms in the embodiments of the utility model according to the specific circumstances.

[0061] In the description of the utility model embodiments, it should be understood that the terms "upper", "lower", "left", "right", "front", "rear", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the drawings. They are only for the convenience of describing the utility model embodiments and simplifying the description, and do not indicate or imply that the device or unit referred to must have a specific orientation or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on the utility model embodiments.

[0062] The above are merely preferred embodiments of the utility model and are not intended to limit the utility model. For those skilled in the art, various modifications and variations can be made to the utility model. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the utility model should be included within the protection scope of the utility model.

Claims

1. A dynamic incubation device capable of loading a slide, characterized in that, The device includes a cover plate and a support assembly. The support assembly includes a pair of side plates and a pair of pushers. The pair of pushers are slidably connected to the pair of side plates and connected to both sides of the cover plate. Each pair of side plates is provided with a fixing member and a support member. The fixing member is used to load and fix the carrier plate, and the support member is used to support the bottom of the carrier plate and restrict the carrier plate from sliding out from the bottom of the side plate. The carrier plate is supported between a pair of fixed members; the pusher slides under the drive of an external force, forcing the cover plate to open and close relative to the carrier plate.

2. The dynamic incubation device of claim 1, wherein, The fastener is a slot, which is located on the side plate.

3. The dynamic incubation device of claim 1, wherein, The fastener includes a first fixing plate and a second fixing plate, and a slot is formed between the first fixing plate and the second fixing plate.

4. The dynamic incubation device of claim 3, wherein, The second fixing plate is located above the first fixing plate, and the top of the second fixing plate is provided with a guide surface, which is used to guide the carrier to be inserted into the slot.

5. The dynamic incubation device of claim 3, wherein, The first fixing plate and the second fixing plate are disposed on the top of the side plate, and the support member is disposed on the bottom of the side plate; a first support plate is disposed in the middle of the side plate, and the first support plate is used to support the middle of the carrier.

6. The dynamic incubation device according to claim 5, characterized in that, The first fixing plate, the second fixing plate, the first support plate, and the support member are either integrally formed with the side plate or separately formed.

7. The dynamic incubation device of claim 5, wherein, The support member includes a second support plate and a limiting block. The second support plate is used to support the bottom of the carrier, and the limiting block is used to abut the bottom end of the carrier; or, the support member is a step that extends inward from the bottom of the side plate and protrudes.

8. The dynamic incubation device of claim 1, wherein, The cover plate has outwardly extending protrusions on both sides, and the pusher has a groove to support the protrusions. The top of the groove has a slot opening, and the protrusions can enter and exit the slot opening.

9. The dynamic incubation device of claim 8, wherein, The bottom of the cover plate is provided with a liquid guiding part, which extends downward from the bottom surface of the cover plate and converges; and / or the top of the cover plate is provided with a support part, which can abut against the downstream fixing member to separate the cover plate from the carrier.

10. The dynamic incubation device of claim 1, wherein, The support assembly includes multiple pairs of side plates and multiple pairs of pushers. The multiple pairs of pushers are slidably connected to the multiple pairs of side plates, and two adjacent side plates form a connecting plate.