A compact micro-sampler

Abstract

The utility model discloses a compact micro -sampler, compact micro -sampler includes: by upper and lower sequentially set the cover plate, flow channel layer, valve membrane layer and base, the upper surface of flow channel layer and cover plate bond formation flow channel cavity, be provided with sample hole, chromatographic column connecting port and carrier gas export on the cover plate, the lower surface of flow channel layer with base between based on valve membrane layer carries out hot pressure bond processing and realizes the bond, be provided with first port and second port respectively on the base. The utility model discloses by upper and lower sequentially set the cover plate, flow channel layer, valve membrane layer and base, based on the bond process assembly integration, and the whole structure is simple and compact, effectively reduces the space occupancy, the upper surface of flow channel layer and cover plate bond formation flow channel cavity, cooperate the through -hole of being set up with flow channel cavity intercommunication on the cover plate and base, realized the injection of sample gas and carrier gas.

Description

Technical Field

[0001] This utility model relates to the field of sample injector technology, and in particular to a compact micro sample injector. Background Technology

[0002] Micro-GC is an analytical instrument that achieves miniaturization, integration, and portability by utilizing microelectromechanical systems (MEMS) technology, building upon traditional gas chromatography. Its core objective is to reduce volume, weight, and power consumption by one to two orders of magnitude while maintaining high separation efficiency, meeting the needs of rapid on-site detection (such as environmental monitoring, chemical safety, medical diagnostics, and space exploration). The injector, as the "entry point" of Micro-GC, directly determines analytical accuracy and reliability, making it one of the most challenging modules in the miniaturization process.

[0003] Microsamplers can precisely introduce minute amounts of sample (nanoli to microliter), enabling instantaneous injection of gaseous / volatile liquid samples, avoiding sample diffusion, maintaining "plug flow" injection, and preventing residues and cross-contamination.

[0004] Existing micro-injectors are complex in structure and occupy a large space. Therefore, there is an urgent need for a new micro-injector with a compact structure. Utility Model Content

[0005] In view of the above problems, the present invention is proposed to provide a compact micro-injector that overcomes or at least partially solves the above problems.

[0006] This invention provides a compact micro-injector, comprising: a flow channel layer, a cover plate, a valve membrane layer, and a base, arranged sequentially from top to bottom; the upper surface of the flow channel layer is bonded to the cover plate to form a flow channel cavity, the cover plate being provided with an injection port, a column connection port, and a carrier gas outlet, all of which are connected to the flow channel cavity; the lower surface of the flow channel layer is bonded to the base via a thermo-pressing bonding process based on the valve membrane layer, and the base being provided with a first port and a second port, both of which are connected to the flow channel cavity.

[0007] Optionally, the flow channel cavity includes a sample inlet pipe, a sampling valve, a transfer pipe, an injection channel, an injection valve, a flow channel inlet, an exhaust pipe, a sample gas outlet, and a carrier gas inlet; one end of the sample inlet pipe is connected to the sampling valve, and the other end of the sample inlet pipe is connected to the injection port; the two ends of the transfer pipe are a first connection end and a second connection end, respectively, the first connection end being connected to the sampling valve, and the second connection end being connected to the injection valve; one end of the exhaust pipe is connected to the chromatographic column connection port, and the other end of the exhaust pipe is connected to the injection valve; one end of the injection channel is connected to the injection valve through the flow channel inlet, and the other end of the injection channel is connected to the second port through the sample gas outlet; the carrier gas inlet is connected to the first port, and the carrier gas inlet is connected to the injection valve through a carrier gas pipe.

[0008] Optionally, the injection valve is a pneumatic valve. When the injection valve is open, the second connection end and the carrier gas pipeline are both connected to the flow channel inlet, and the exhaust pipeline is not connected to the injection valve. When the injection valve is closed, the second connection end and the carrier gas pipeline are both connected to the exhaust pipeline, and the flow channel inlet is not connected to the injection valve.

[0009] Optionally, the sampling valve is a pneumatic valve. When the sampling valve is open, the sample inlet pipe and the transfer pipe are not connected. When the sampling valve is closed, the sample inlet pipe and the transfer pipe are connected.

[0010] Optionally, the carrier gas pipeline is also connected to a pressure relief pipeline, and the pressure relief pipeline is provided with a carrier gas pressure relief port at the position corresponding to the carrier gas outlet, and the carrier gas outlet is connected to the carrier gas pressure relief port.

[0011] Optionally, the cover plate is made of BF33 glass.

[0012] Optionally, the material of the flow channel layer is silicon.

[0013] Optionally, the valve membrane layer is made of polyimide film; the thickness of the polyimide film is 12.5~100μm.

[0014] Optionally, a first through hole and a second through hole are respectively opened on the valve diaphragm layer at the positions corresponding to the first port and the second port.

[0015] Optionally, the base is made of BF33 glass or silicon.

[0016] The technical solution provided in this embodiment of the utility model has at least the following technical effects or advantages: The compact micro-injector described in this embodiment consists of a cover plate, a flow channel layer, a valve membrane layer, and a base arranged sequentially from top to bottom, assembled into one unit using a bonding process. The overall structure is simple and compact, effectively reducing space occupation. The upper surface of the flow channel layer is bonded to the cover plate to form a flow channel cavity. With the through holes on the cover plate and the base that communicate with the flow channel cavity, the injection of sample gas and carrier gas is realized.

[0017] The above description is merely an overview of the technical solution of this utility model. In order to better understand the technical means of this utility model and to implement it in accordance with the contents of the specification, and to make the above and other objects, features and advantages of this utility model more obvious and understandable, specific embodiments of this utility model are given below. Attached Figure Description

[0018] To more clearly illustrate the technical solutions in the embodiments of this utility model, the drawings used in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0019] Figure 1 This is an exploded view of the compact micro-sampler described in this utility model. Figure 2 This is a perspective view of the connection of the compact micro-injector described in this utility model; Figure 3 This is a schematic diagram of the flow channel layer described in this utility model; Figure 4 This is a schematic diagram of the bottom structure of the flow channel layer described in this utility model.

[0020] Explanation of reference numerals in the attached figures: 1. Flow channel layer; 2. Cover plate; 3. Valve membrane layer; 4. Base; 11. Sample inlet pipe; 12. Sampling valve; 13. Transfer pipe; 14. Sample inlet flow channel; 15. Sample inlet valve; 16. Flow channel inlet; 17. Exhaust pipe; 18. Sample gas outlet; 19. Carrier gas inlet; 21. Sample inlet port; 22. Column connection port; 23. Carrier gas outlet; 31. First port; 32. Second port; 41. First through hole; 42. Second through hole; 131. First connection end; 132. Second connection end; 191. Pressure relief pipe; 192. Carrier gas pipe; 193. Carrier gas pressure relief port. Detailed Implementation

[0021] Exemplary embodiments of the present disclosure will now be described in more detail with reference to the accompanying drawings.

[0022] To enable those skilled in the art to better understand the present invention, the technical solutions of the present invention will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, and not all of them. The accompanying drawings show preferred embodiments of the present invention. The present invention can be implemented in many different forms and is not limited to the embodiments described herein. Rather, these embodiments are provided to make the disclosure of the present invention more thorough and complete.

[0023] Unless otherwise specified, all raw materials, instruments and equipment used in this invention can be purchased from the market or prepared by existing methods.

[0024] Figure 1 This is a schematic diagram of the structure of a compact micro-sampler provided in an embodiment of this utility model. Figure 2 This is a perspective view of the connection of the compact micro-injector described in this utility model. (See reference) Figure 1-2 As shown, the compact microsyringe includes a flow channel layer 1, a cover plate 2, a valve membrane layer 3, and a base 4, arranged sequentially from top to bottom. The upper surface of the flow channel layer 1 is bonded to the cover plate 2 to form a flow channel cavity. The cover plate 2 is provided with an injection port 21, a column connection port 22, and a carrier gas outlet 23, all of which communicate with the flow channel cavity. The lower surface of the flow channel layer 1 is bonded to the cover plate 2 to form a flow channel cavity. The bases 4 are bonded together by thermo-pressing based on the valve membrane layer 3. The bases 4 are respectively provided with a first port 31 and a second port 32, both of which are connected to the flow channel cavity. The sample inlet 21 is used to introduce sample gas, the first port 31 is used to introduce carrier gas, the column connection port 22 is used to connect the column, the carrier gas outlet 23 is used to discharge part of the carrier gas to balance the gas pressure in the flow channel cavity, and the second port 32 is used to discharge sample gas.

[0025] In this embodiment of the invention, the cover plate 2 is made of BF33 glass and is used to form an encapsulation structure with the flow channel layer 1 and generate a flow channel cavity.

[0026] The flow channel layer 1 is made of silicon, and the cover plate 2 is applied to the upper surface of the flow channel layer 1 and bonded to the flow channel layer 1 to form a flow channel cavity.

[0027] The valve membrane layer 3 is made of polyimide film (polyimide thin film), which has good insulation properties. The flow channel layer 1 and the base 4 are bonded to each other by hot-press bonding based on the valve membrane layer 3. The hot-press bonding process is performed at a temperature of 300~360°C and a pressure of 0.1~0.5MPa, preferably 320°C and 0.18MPa. The thickness of the polyimide film is 12.5~100μm.

[0028] The valve diaphragm layer 3 has a first through hole 41 and a second through hole 42 respectively corresponding to the positions of the first port 31 and the second port 32, so that the first port 31, the first through hole 41 and the flow channel cavity are connected in sequence, and the second port 32, the second through hole 42 and the flow channel cavity are connected in sequence.

[0029] The base 4 is made of BF33 glass or silicon.

[0030] Figure 3 This is a schematic diagram of the flow channel layer 1 described in this utility model. Figure 4 This is a schematic diagram of the bottom structure of the flow channel layer 1 described in this utility model, combined with... Figure 2-4 As shown, the flow channel cavity includes a sample inlet pipe 11, a sampling valve 12, a transfer pipe 13, a sample inlet channel 14, a sample inlet valve 15, a flow channel inlet 16, an exhaust pipe 17, a sample gas outlet 18, and a carrier gas inlet 19; one end of the sample inlet pipe 11 is connected to the sampling valve 12, and the other end of the sample inlet pipe 11 is connected to the sample inlet port 21; the two ends of the transfer pipe 13 are a first connection end 131 and a second connection end 132, respectively. The first connection end 131 is connected to the sampling valve 12, and the second connection end 132 is connected to the sampling valve 12. Terminal 132 is connected to the injection valve 15; one end of the exhaust line 17 is connected to the column connection port 22, and the other end of the exhaust line 17 is connected to the injection valve 15; one end of the injection channel 14 is connected to the injection valve 15 through the channel inlet 16, and the other end of the injection channel 14 is connected to the second port 32 through the sample gas outlet 18; the carrier gas inlet 19 is connected to the first port 31, and the carrier gas inlet 19 is connected to the injection valve 15 through the carrier gas line 192.

[0031] In this embodiment of the invention, the injection valve 15 is a conventional pneumatic valve. The injection valve 15 is used to adjust the gas flow direction of the second connection end 132, the exhaust line 17, the flow channel inlet 16, and the carrier gas line 192 to achieve gas path switching. When the injection valve 15 is open, the second connection end 132 and the carrier gas line 192 are both connected to the flow channel inlet 16, and the exhaust line 17 is not connected to the injection valve 15. When the injection valve 15 is closed, the second connection end 132 and the carrier gas line 192 are both connected to the exhaust line 17, and the flow channel inlet 16 is not connected to the injection valve 15. Thus, by opening and closing the injection valve 15, the flow direction of the sample gas can be adjusted to either be directly fed into the chromatographic column through the exhaust line 17, or circulated through the injection flow channel 14 and discharged from the sample gas outlet 18.

[0032] The sampling valve 12 is a conventional pneumatic valve. The sampling valve 12 is used to control the connectivity between the sample inlet pipe 11 and the transfer pipe 13 to achieve gas path switching. That is, when the sampling valve 12 is open, the sample inlet pipe 11 and the transfer pipe 13 are not connected. When the sampling valve 12 is closed, the sample inlet pipe 11 and the transfer pipe 13 are connected, thereby controlling whether the sample gas enters the flow channel cavity.

[0033] In other embodiments of this utility model, the injection valve 15 and the sampling valve 12 may also be other types of control valves, as long as they can realize the switching of the gas path. This utility model embodiment does not limit this.

[0034] In this embodiment of the present invention, the carrier gas pipeline 192 is also connected to a pressure relief pipeline 191. The pressure relief pipeline 191 is provided with a carrier gas pressure relief port 193 at the position corresponding to the carrier gas outlet 23. The carrier gas outlet 23 is connected to the carrier gas pressure relief port 193, so that when the carrier gas is introduced into the flow channel cavity, the carrier gas overflowing from the carrier gas pipeline 192 is discharged synchronously through the pressure relief pipeline 191 and the carrier gas pressure relief port 193, thereby achieving gas pressure balance in the corresponding pipeline.

[0035] In this embodiment of the present invention, the sample inlet channel 14, the carrier gas line 192, and the pressure relief line 191 are all bent serpentine channels, and the corresponding pipelines of the sample inlet channel 14, the carrier gas line 192, and the pressure relief line 191 are evenly arranged around each pneumatic valve or through hole (such as the sample inlet 21, the chromatographic column connection port 22, the carrier gas outlet 23, the first port 31, and the second port 32, etc.), which greatly improves the space utilization rate of the channel layer 1 and further reduces the space occupation problem while maintaining the same channel function.

[0036] To further maintain the pressure balance between the carrier gas pipeline 192 and the pressure relief pipeline 191, the carrier gas pipeline 192 and the pressure relief pipeline 191 are of the same length and have the same number of bends. This ensures that when the carrier gas enters the carrier gas pipeline 192 and the pressure relief pipeline 191 respectively, the flow environment and flow length are under the same conditions, thereby achieving pressure balance within the gas pipelines.

[0037] The compact micro-injector described in this embodiment of the invention consists of a cover plate 2, a flow channel layer 1, a valve membrane layer 3, and a base 4 arranged sequentially from top to bottom. These components are assembled into a single unit using a bonding process, resulting in a simple and compact overall structure that effectively reduces space occupancy. The upper surface of the flow channel layer 1 is bonded to the cover plate 2 to form a flow channel cavity. Through-holes (such as injection port 21, column connection port 22, carrier gas outlet 23, first port 31, and second port 32) on the cover plate 2 and base 4 that communicate with the flow channel cavity enable the injection of sample gas and carrier gas. Furthermore, the injection flow channel 14, carrier gas line 192, and pressure relief line 191 are all bent serpentine flow channels. While maintaining the same flow channel function, the compact structure further reduces space occupancy and lowers production costs.

[0038] Numerous specific details are set forth in the specification provided herein. However, it will be understood that embodiments of the present invention may be practiced without these specific details. In some instances, well-known methods, structures, and techniques have not been shown in detail so as not to obscure the understanding of this specification.

[0039] Similarly, it should be understood that, in order to simplify this disclosure and aid in understanding one or more of the various aspects of the invention, various features of the invention are sometimes grouped together in a single embodiment, figure, or description thereof in the description of exemplary embodiments of the invention above. Other embodiments of this disclosure will readily occur to those skilled in the art upon consideration of the specification and practice of the disclosure herein. This application is intended to cover any variations, uses, or adaptations of this disclosure that follow the general principles of this disclosure and include common knowledge or customary techniques in the art not disclosed herein. The specification and embodiments are to be considered exemplary only, and it should be noted that the above embodiments are illustrative of the invention and not restrictive, and that alternative embodiments can be devised by those skilled in the art without departing from its scope.

Claims

1. A compact micro-injector, characterized in that, The compact micro-injector includes a flow channel layer, a cover plate, a valve membrane layer, and a base, arranged sequentially from top to bottom. The upper surface of the flow channel layer is bonded to the cover plate to form a flow channel cavity. The cover plate is provided with an injection port, a column connection port, and a carrier gas outlet, all of which are connected to the flow channel cavity. The lower surface of the flow channel layer is bonded to the base via a thermo-pressing bonding process based on the valve membrane layer. The base is provided with a first port and a second port, both of which are connected to the flow channel cavity.

2. The compact micro-injector according to claim 1, characterized in that: The flow channel cavity includes a sample inlet pipe, a sampling valve, a transfer line, an injection channel, an injection valve, a flow channel inlet, an exhaust line, a sample gas outlet, and a carrier gas inlet. One end of the sample inlet pipe is connected to the sampling valve, and the other end of the sample inlet pipe is connected to the injection port. The two ends of the transfer line are a first connection end and a second connection end, respectively. The first connection end is connected to the sampling valve, and the second connection end is connected to the injection valve. One end of the exhaust line is connected to the chromatographic column connection port, and the other end of the exhaust line is connected to the injection valve. One end of the injection channel is connected to the injection valve through the flow channel inlet, and the other end of the injection channel is connected to the second port through the sample gas outlet. The carrier gas inlet is connected to the first port, and the carrier gas inlet is connected to the injection valve through a carrier gas line.

3. The compact micro-injector according to claim 2, characterized in that: The injection valve is a pneumatic valve. When the injection valve is open, the second connection end and the carrier gas pipeline are both connected to the flow channel inlet, and the exhaust pipeline is not connected to the injection valve. When the injection valve is closed, the second connection end and the carrier gas pipeline are both connected to the exhaust pipeline, and the flow channel inlet is not connected to the injection valve.

4. The compact micro-injector according to claim 2, characterized in that: The sampling valve is a pneumatic valve. When the sampling valve is open, the sample inlet pipe and the transfer pipe are not connected. When the sampling valve is closed, the sample inlet pipe and the transfer pipe are connected.

5. The compact micro-injector according to claim 2, characterized in that: The carrier gas pipeline is also connected to a pressure relief pipeline, and the pressure relief pipeline is provided with a carrier gas pressure relief port at the position corresponding to the carrier gas outlet. The carrier gas outlet is connected to the carrier gas pressure relief port.

6. The compact micro-injector according to claim 1, characterized in that: The cover plate is made of BF33 glass.

7. The compact micro-injector according to claim 1, characterized in that: The material of the flow channel layer is silicon.

8. The compact micro-injector according to claim 1, characterized in that: The valve diaphragm layer is made of polyimide film; the thickness of the polyimide film is 12.5~100μm.

9. The compact micro-injector according to claim 8, characterized in that: The valve diaphragm layer has a first through hole and a second through hole respectively corresponding to the positions of the first port and the second port.

10. The compact micro-injector according to claim 1, characterized in that: The base is made of BF33 glass or silicon.

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