Pulse sampling device and tissue ablation apparatus

Abstract

The application discloses a pulse sampling device and a tissue ablation device, which are used for sampling and processing output pulses of a pulse output device. The pulse sampling device comprises a sampling module, a gear switching module, a signal processing circuit, and a controller. The sampling module is used for sampling output pulses to obtain a sampling voltage signal. The gear switching module is connected to the sampling module and comprises at least one gear switching circuit. After receiving a gear switching signal, the gear switching module uses a target gear switching circuit to divide the sampling voltage signal to output a divided voltage signal. The signal processing circuit is connected to the gear switching module and is used for converting the divided voltage signal into a digital voltage signal. The controller is connected to the gear switching module and the signal processing circuit respectively. The controller is used for obtaining working parameters, determining the target gear switching circuit based on the working parameters, and generating the gear switching signal. The working parameters are used for indicating the voltage of the output pulses. The controller is also used for sampling the digital voltage signal.

Description

Technical Field

[0001] This application relates to the field of pulsed electric field ablation technology, and in particular to a pulse sampling device and tissue ablation equipment. Background Technology

[0002] Pulsed field ablation (PFA) is a novel tissue ablation technique based on physical energy factors that has emerged in recent years. It primarily utilizes the principle of irreversible electroporation, applying a high-voltage pulsed electric field to cells to cause irreversible perforation of the cell membrane, leading to gradual cell necrosis and ultimately tissue ablation. In irreversible electroporation tumor treatment systems, the duration of the high-voltage pulse can be measured in milliseconds, microseconds, and nanoseconds. Shorter pulse durations result in less stimulation of the muscles, while simultaneously requiring more precise sampling of the output voltage and current of the high-voltage pulse. In related technologies, a PICO acquisition module (a type of pocket oscilloscope) is typically used as the pulse sampling device. However, the sampling accuracy of the PICO module is insufficient to meet the high-precision control requirements of the high-voltage pulse in pulsed field ablation scenarios. Utility Model Content

[0003] In view of this, embodiments of this application provide a pulse sampling device and a tissue ablation device, which aim to improve the sampling rate of electrical pulses and meet the requirements for high-precision control.

[0004] In a first aspect, embodiments of this application provide a pulse sampling device for sampling and processing the output pulses of a pulse output device, the pulse sampling device comprising:

[0005] A sampling module is used to sample the output pulse to obtain a sampled voltage signal, and to output the sampled voltage signal;

[0006] A gear shifting module is electrically connected to the sampling module. The gear shifting module includes at least one gear shifting circuit, which, upon receiving a gear shifting signal, uses a target gear shifting circuit to divide the sampled voltage signal to output a divided voltage signal. The at least one gear shifting circuit includes the target gear shifting circuit, and the at least one gear shifting circuit is connected in parallel.

[0007] A signal processing circuit, which is electrically connected to the gear shifting module, is used to convert the voltage divider signal into a digital voltage signal.

[0008] The controller is connected to the gear shifting module and the signal processing circuit respectively, and is used to acquire operating parameters, determine the target gear shifting circuit in the gear shifting module based on the operating parameters, and generate the gear shifting signal. The operating parameters are used to indicate the voltage of the output pulse.

[0009] The controller is also used to sample the digital voltage signal.

[0010] In some embodiments, the pulse sampling device further includes:

[0011] An electro-optical conversion circuit is used to receive an electrical signal containing the operating parameters and convert the electrical signal into an optical signal;

[0012] A photoelectric conversion circuit, connected to the controller, is used to convert the optical signal into an electrical signal containing the operating parameters and send it to the controller;

[0013] The optical fiber module is disposed between the electro-optical conversion circuit and the photoelectric conversion circuit, and is used to receive the optical signal and transmit it to the photoelectric conversion circuit.

[0014] In some implementations, each of the gear shifting circuits includes a gear switch;

[0015] The controller is specifically used to: determine the target gear shifting circuit in the gear shifting module based on the operating parameters and the first mapping relationship, and generate the gear shifting signal;

[0016] The target gear shifting circuit includes a gear switch that is turned on after receiving the gear shifting signal.

[0017] In some implementations, each of the gear shifting circuits further includes a first voltage divider circuit and a second voltage divider circuit;

[0018] The input terminal of the first voltage divider circuit is connected to the sampling module, the output terminal of the first voltage divider circuit is connected to the input terminal of the gear switch, and the output terminal of the gear switch is connected to the signal processing circuit; the input terminal of the second voltage divider circuit is connected to the output terminal of the first voltage divider circuit, and the output terminal of the second voltage divider circuit is grounded.

[0019] Alternatively, the input terminal of the first voltage divider circuit is connected to the sampling module, the output terminal of the first voltage divider circuit is connected to the input terminal of the gear switch, the output terminal of the gear switch is connected to the signal processing circuit and the input terminal of the second voltage divider circuit respectively, and the output terminal of the second voltage divider circuit is grounded.

[0020] In some implementations, both the first voltage divider circuit and the second voltage divider circuit include resistors and capacitors connected in parallel.

[0021] In some implementations, the pulse sampling device further includes a conversion circuit, the input of which is connected to the gear switching module, and the output of which is connected to the signal processing circuit.

[0022] The conversion circuit is used to convert the voltage divider signal into a differential signal and output it to the signal processing circuit; the signal processing circuit is also used to convert the differential signal into a digital voltage signal.

[0023] In some implementations, the sampling module includes a coaxial connector for receiving the sampled voltage signal and transmitting the sampled voltage signal to the target gear switching circuit.

[0024] In some implementations, the controller is also used to control the voltage of the output pulse of the pulse output device based on the operating parameters.

[0025] In some embodiments, the pulse sampling device further includes a power supply circuit, which includes a power input port, a first voltage conversion circuit, a capacitor charging and discharging circuit, and a second voltage conversion circuit.

[0026] The output terminal of the power input port is connected to the input terminal of the first voltage conversion circuit. The output terminal of the first voltage conversion circuit is connected to the input terminal of the capacitor charging and discharging circuit and the controller. The output terminal of the capacitor charging and discharging circuit is connected to the controller and the input terminal of the second voltage conversion circuit. The output terminal of the second voltage conversion circuit is connected to the controller.

[0027] The first voltage conversion circuit is used to convert the voltage output from the power input port into a first supply voltage and supply power to the controller;

[0028] The capacitor charging and discharging circuit is used to charge the capacitor according to the first power supply voltage, and output the first power supply voltage to the second voltage conversion circuit after charging is completed.

[0029] The second voltage conversion circuit is used to convert the first supply voltage into the second supply voltage and supply power to the controller;

[0030] The capacitor charging and discharging circuit is also used to supply power to the controller and the second voltage conversion circuit when there is no output voltage at the power input port.

[0031] Secondly, embodiments of this application provide a tissue ablation device, including a pulse output device and a pulse sampling device as described in the first aspect.

[0032] This application provides a pulse sampling device for sampling and processing the output pulses of a pulse output device. The pulse sampling device includes: a sampling module, a gear switching module, a signal processing circuit, and a controller. The sampling module samples the output pulses to obtain a sampled voltage signal and an output sampled voltage signal. The gear switching module is electrically connected to the sampling module. The gear switching module includes at least one gear switching circuit, which, upon receiving a gear switching signal, divides the sampled voltage signal using a target gear switching circuit to output a divided voltage signal. The at least one gear switching circuit includes a target gear switching circuit, and the at least one gear switching circuit is connected in parallel. The signal processing circuit is electrically connected to the gear switching module and converts the divided voltage signal into a digital voltage signal. The controller is connected to both the gear switching module and the signal processing circuit, and is used to acquire operating parameters, determine the target gear switching circuit in the gear switching module based on the operating parameters, and generate a gear switching signal. The operating parameters indicate the voltage of the output pulse. The controller is also used to sample the digital voltage signal.

[0033] Thus, in the solution provided by this application embodiment, when the tissue ablation device is working, the controller receives the pulse voltage to be emitted by the pulse output device input by the user. The controller determines the target gear switching circuit according to the magnitude of the pulse voltage, thereby selecting the appropriate gear switching circuit to divide the sampled voltage signal, so that the divided signal meets the measurement range requirements of the subsequent circuit. This is beneficial to improving the sampling accuracy of the electrical pulse of the pulse sampling device, enabling the tissue ablation device to detect more realistic parameters of the output pulse, thereby helping to control the output pulse more accurately. Attached Figure Description

[0034] Figure 1 This is a schematic diagram of the pulse sampling device provided in the embodiments of this application;

[0035] Figure 2 A schematic diagram of a pulse sampling device including an electro-optical conversion circuit, a photoelectric conversion circuit, and an optical fiber module, provided for embodiments of this application;

[0036] Figure 3 A circuit diagram of a gear shifting module provided in an embodiment of this application;

[0037] Figure 4 This is a circuit diagram of another gear shifting module provided in an embodiment of this application;

[0038] Figure 5 A schematic diagram of a pulse sampling device including a conversion circuit is provided for an embodiment of this application;

[0039] Figure 6 A schematic diagram of a pulse sampling device including a synchronous trigger circuit is provided for an embodiment of this application;

[0040] Figure 7 A schematic diagram of a pulse sampling device including a power supply circuit is provided for an embodiment of this application;

[0041] Figure 8 A circuit diagram of the power supply circuit provided for the application example of this application. Detailed Implementation

[0042] The present application will now be described in further detail with reference to the accompanying drawings and embodiments.

[0043] It should be understood that the examples and illustrations in this application are for illustrative purposes, and deviations and variations can be constructed and deployed based on the teachings of this application without departing from the scope of this application. Before detailing at least one embodiment of this application, it should be understood that this application is not necessarily limited to the detailed configuration and arrangement of the components and / or methods set forth in the following description and / or illustrated in the drawings and / or embodiments. This application can have other embodiments or can be practiced or implemented in different ways.

[0044] Unless otherwise defined, all technical and / or scientific terms used in this application have the same meaning as commonly understood by one of ordinary skill in the art to which this application pertains. While similar or equivalent methods and materials described in this application may be used to practice or test embodiments of this application, exemplary methods and / or materials are described below. In the event of any conflict, the specification (including definitions) of this application shall prevail. Furthermore, these materials, methods, and embodiments are illustrative only and are not intended to impose any necessary limitations.

[0045] In one possible implementation, a pulse sampling device is provided for sampling the output pulse of the pulse output device, such as... Figure 1 As shown, the pulse sampling device includes: a sampling module 101, a gear switching module 102, a signal processing circuit 103, and a controller 104; wherein,

[0046] The sampling module 101 is used to sample the output pulse to obtain a sampled voltage signal and an output sampled voltage signal;

[0047] The gear shifting module 102 is electrically connected to the sampling module 101. The gear shifting module 102 includes at least one gear shifting circuit, which is used to divide the sampled voltage signal by the target gear shifting circuit after receiving the gear shifting signal, so as to output the divided voltage signal. The at least one gear shifting circuit includes the target gear shifting circuit, and the at least one gear shifting circuit is connected in parallel.

[0048] The signal processing circuit 103 is electrically connected to the gear shifting module 102 and is used to convert the voltage divider signal into a digital voltage signal.

[0049] The controller 104 is connected to the gear shifting module 102 and the signal processing circuit 103 respectively. It is used to acquire working parameters, determine the target gear shifting circuit in the gear shifting module 102 based on the working parameters, and generate a gear shifting signal. The working parameters are used to indicate the voltage of the output pulse.

[0050] Controller 104 is also used to sample digital voltage signals.

[0051] In one possible implementation, the controller 104 may include at least one of the following: a microcontroller unit (MCU), a system-on-chip (SoC), a digital signal processor (DSP), or a field-programmable gate array (FPGA). This application does not limit the specific device type and model of the controller 104. The signal processing circuit 103 includes an AD conversion chip, which can employ a 2-channel parallel 12-bit ADC interface. The chip's clock is provided by the controller 104, and the output digital voltage signal can be output in parallel, which helps improve real-time performance during high-speed acquisition.

[0052] In one possible implementation, the pulse output device typically has multiple electrodes for outputting pulses, and also multiple output ports. Therefore, the sampling module 101 can receive at least one sampling voltage signal, each representing the voltage information of a specific output port of the pulse output device. The tissue ablation device includes a sampling circuit for sampling the output pulses. The sampling circuit can acquire the sampling voltage signal and output it to the sampling module 101. The sampling voltage signal actually output to the sampling module 101 can be a voltage signal that has undergone voltage reduction processing, or it can be a voltage signal that has not undergone voltage reduction processing; this application does not limit this.

[0053] In some implementations, the controller 104 acquires the operating parameters input by the controller to indicate the output pulse voltage. The controller 104 determines the target gear switching circuit based on the operating parameters and turns on the target gear switching circuit. Thus, the sampled voltage signal is divided into a divided voltage signal after passing through the target gear switching circuit. The divided voltage signal enters the signal processing circuit 103 for analog-to-digital conversion to output a digital voltage signal to the controller 104. The controller 104 can sample the digital voltage signal, which helps to display more realistic pulse-related parameters on the display receiver, or to adjust the output pulse voltage based on more realistic pulse voltage information, thereby helping to control the output pulse more accurately.

[0054] Understandably, when the tissue ablation device is working, the controller 104 receives the pulse voltage to be output by the pulse output device input by the user. The controller 104 determines the target gear switching circuit based on the magnitude of the pulse voltage, and then selects the appropriate gear switching circuit to divide the sampled voltage signal so that the divided signal meets the measurement range requirements of the subsequent circuit. This helps to improve the sampling accuracy of the electrical pulse of the pulse sampling device, enabling the tissue ablation device to detect more realistic parameters of the output pulse, thereby helping to control the output pulse more accurately.

[0055] In one possible implementation, the voltage value of the voltage divider signal is less than or equal to the product of the range value of the signal processing circuit and a set ratio.

[0056] Optionally, the signal conversion circuit is an AD conversion circuit.

[0057] Since the nonlinearity error of most AD conversion chips gradually increases after the middle of their range, dividing the sampled voltage signal to a value less than or equal to the product of the AD conversion chip value and a set ratio ensures that the sampling point is within the optimal linearity range of the AD conversion chip. This minimizes sampling errors caused by the nonlinear characteristics of the device itself and helps to accurately reproduce the amplitude, waveform, and other characteristics of the pulse signal. For example, the set ratio can be 50%, i.e., half of the full-scale range of the AD conversion chip. This application does not limit the specific value of the set ratio in its embodiments.

[0058] In related technologies, the pulse output device (or pulse generation component) is the part connected to the patient, and the display receiver (or operation component) is the part connected to the operator. Electrical isolation is required between the pulse output device and the display receiver. Most existing isolation methods are to isolate the RS-422 interface (an interface with added electrical isolation design based on the RS-422 serial communication standard) or the USB interface. However, the communication rate of existing isolation methods is insufficient, and the transmission of each signal requires the isolation interface to be connected to the PICO acquisition module, resulting in the dispersion of the various modules of the tissue ablation device.

[0059] In one possible implementation, such as Figure 2 As shown, the pulse sampling device further includes:

[0060] The electro-optical conversion circuit 105 is used to receive an electrical signal containing the operating parameters and convert the electrical signal into an optical signal;

[0061] The photoelectric conversion circuit 107 is connected to the controller 104 and is used to convert the optical signal into an electrical signal containing the operating parameters and send it to the controller 104.

[0062] The optical fiber module 106 is disposed between the electro-optical conversion circuit 105 and the photoelectric conversion circuit 107, and is used to receive the optical signal and transmit it to the photoelectric conversion circuit 107.

[0063] In some implementations, the fiber optic module 106 can not only receive optical signals containing operating parameter information and transmit them to the photoelectric conversion circuit 107, but also transmit the pulse voltage information sampled by the controller 104 to the display receiver in the form of optical signals. This solves the isolation withstand voltage requirements between the high-voltage section and the operator section, and avoids electromagnetic interference between devices. The aforementioned electro-optical conversion circuit 105 and / or photoelectric conversion circuit 107 can be implemented using gigabit optical modules, which helps improve the real-time performance and speed of data transmission while ensuring isolation between the controller 104 and the display receiver.

[0064] For example, the gigabit optical module includes two differential pairs, which are transmission structures consisting of two signal lines used to transmit differential signals. If the controller 104 is an FPGA, the differential pairs can be driven by the FPGA's MGT-BANK (a dedicated hardware module for FPGA to implement high-speed serial communication). That is, the MGT-BANK can provide high-speed and stable communication pins to the differential pairs, ensuring the speed and accuracy of differential signal transmission. One differential pair can support a transmission rate of up to 6.25Gbps. Furthermore, the gigabit optical module can adapt to single-fiber or multi-fiber output, eliminating the need for isolated RS-422 or isolated USB interfaces to connect the display receiver and the controller 104, thus reducing the complexity of system wiring. Specifically, the gigabit optical module can achieve differential signal input through ports TD+ and TD-. Ports TD+ and TD- are used to receive electrical signals containing operating parameters, and the laser driver uses the electrical signals to drive the laser diode, converting the electrical signals into optical signals. The optical signals are transmitted to the photodiode through the fiber optic interface. The photodiode generates a weak current, which is input to the amplifier module to amplify the weak current signal. Finally, the differential electrical signal is output through ports RD+ and RD-, and the electrical signal is output to the controller 104. In one possible implementation, each of the gear switching circuits includes a gear switch.

[0065] The controller 104 is specifically used to: determine the target gear shifting circuit in the gear shifting module 102 based on the operating parameters and the first mapping relationship, and generate the gear shifting signal;

[0066] The target gear shifting circuit includes a gear switch that is turned on after receiving the gear shifting signal.

[0067] In some implementations, the first mapping relationship includes a mapping relationship between operating parameters and target gear switching circuits. The first mapping relationship is stored in the controller 104, and can specifically be a mapping table. The principle for establishing the first mapping relationship includes ensuring that the sampled voltage signal can be accurately acquired. For example, a pulse with an output voltage of 500V corresponds to the first gear switching circuit in the gear switching module 102, and a pulse with an output voltage of 400V corresponds to the second gear switching circuit in the gear switching module 102. This application embodiment does not limit the specific content of the first mapping relationship.

[0068] For example, the controller 104 receives operating parameters from the display receiver, such as specifying that the voltage of the output pulse is 500V. Based on the first mapping relationship, it determines the first gear switching circuit, that is, the first gear switching circuit is the target gear switching circuit. Therefore, it generates a gear switching signal, controls the gear switch of the target gear switching circuit to close, and controls the gear switches of other gear switching circuits to open, so that the input sampling voltage signal can only pass through the target gear switching circuit.

[0069] The gear switch can be an analog switch. The specific method by which the controller 104 controls the gear switch to close or open can be that the controller 104 outputs a high level to close the gear switch corresponding to the target gear switching circuit, and outputs a low level to open other gear switches.

[0070] In one possible implementation, each of the gear shifting circuits further includes a first voltage divider circuit and a second voltage divider circuit;

[0071] The input terminal of the first voltage divider circuit is connected to the sampling module 101, the output terminal of the first voltage divider circuit is connected to the input terminal of the gear switch, and the output terminal of the gear switch is connected to the signal processing circuit 103; the input terminal of the second voltage divider circuit is connected to the output terminal of the first voltage divider circuit, and the output terminal of the second voltage divider circuit is grounded.

[0072] Alternatively, the input terminal of the first voltage divider circuit is connected to the sampling module 101, the output terminal of the first voltage divider circuit is connected to the input terminal of the gear switch, the output terminal of the gear switch is connected to the signal processing circuit 103 and the input terminal of the second voltage divider circuit respectively, and the output terminal of the second voltage divider circuit is grounded.

[0073] In one possible implementation, both the first voltage divider circuit and the second voltage divider circuit include resistors and capacitors connected in parallel.

[0074] Since the sampled voltage signal is not a stable DC signal, but a mixture of DC and pulse signals, and the fast leading edge (steep rising edge) of the pulse signal contains a large number of high-frequency harmonic components, if only a resistor is used for voltage division, the parasitic inductance of the resistor will impede the high-frequency signal, causing the high-frequency harmonics to be attenuated and the fast leading edge of the pulse signal to be distorted. On the other hand, the capacitive reactance of the capacitor to the fast leading edge of the pulse is extremely small, and it hardly attenuates the high-frequency harmonics. Therefore, using a combination of capacitor and resistor for voltage division allows the resistor to divide the DC signal and the capacitor to divide the fast leading edge of the pulse signal, ensuring the integrity of the signal's fast leading edge. This is beneficial for the controller 104 to perform subsequent signal processing, such as Fast Fourier Transform.

[0075] For example, the circuit structure of a gear shifting module 102 is as follows: Figure 3As shown, the system includes four gear shifting circuits. The first gear shifting circuit includes a gear switch S1A, a first voltage divider circuit including a resistor R1 and a capacitor C1 connected in parallel, and a second voltage divider circuit including a resistor R5 and a capacitor C5 connected in parallel. The second gear shifting circuit includes a gear switch S2A, a first voltage divider circuit including a resistor R2 and a capacitor C2 connected in parallel, and a second voltage divider circuit including a resistor R6 and a capacitor C6 connected in parallel. The third gear shifting circuit includes a gear switch S3A, a first voltage divider circuit including a resistor R3 and a capacitor C3 connected in parallel, and a second voltage divider circuit including a resistor R7 and a capacitor C7 connected in parallel. The fourth gear shifting circuit includes a gear switch S4A, a first voltage divider circuit including a resistor R4 and a capacitor C4 connected in parallel, and a second voltage divider circuit including a resistor R8 and a capacitor C8 connected in parallel.

[0076] from Figure 3 As can be seen, in each gear switching circuit, the voltage signal is divided by the first voltage divider circuit and the second voltage divider circuit to form a divided voltage signal, which is then processed by the closed gear switch input signal processing circuit 103.

[0077] Another type of gear shifting module 102 has the following circuit structure: Figure 4 As shown, different gear switching circuits can share the same second voltage divider circuit. The gear switch is set between the first voltage divider circuit and the second voltage divider circuit. By selecting the gear switch, the voltage is divided by the first voltage divider circuit and the second voltage divider circuit connected in series with the closed gear switch to obtain a divided voltage signal, which is then input to the signal processing circuit 103.

[0078] Specifically, the first voltage divider circuit of the first gear shifting circuit includes a resistor R17 and a capacitor C17 connected in parallel. The resistor R17 and the capacitor C17 are connected to the gear switch S1A. The other end of the gear switch S1A is connected to the second voltage divider circuit. The second voltage divider circuit includes a resistor R16 and a capacitor C16 connected in parallel. The other end of the second voltage divider circuit is grounded.

[0079] The first voltage divider circuit of the second gear switching circuit includes a resistor R18 and a capacitor C18 connected in parallel. The resistor R18 and the capacitor C18 are connected to the gear switch S2A. The other end of the gear switch S2A is connected to the second voltage divider circuit. The second voltage divider circuit includes a resistor R16 and a capacitor C16 connected in parallel. The other end of the second voltage divider circuit is grounded.

[0080] The first voltage divider circuit of the third gear shifting circuit includes a resistor R19 and a capacitor C19 connected in parallel. The resistor R19 and the capacitor C19 are connected to the gear switch S3A. The other end of the gear switch S3A is connected to the second voltage divider circuit. The second voltage divider circuit includes a resistor R16 and a capacitor C16 connected in parallel. The other end of the second voltage divider circuit is grounded.

[0081] The gear switch S4A corresponding to the fourth gear switching circuit has a first voltage divider circuit including a resistor R20 and a capacitor C20 connected in parallel. The resistor R20 and the capacitor C20 are connected to the gear switch S4A. The other end of the gear switch S4A is connected to the second voltage divider circuit. The second voltage divider circuit includes a resistor R16 and a capacitor C16 connected in parallel. The other end of the second voltage divider circuit is grounded.

[0082] Signal transmission is susceptible to electromagnetic interference, power supply noise, environmental interference, and other factors.

[0083] In one possible implementation, such as Figure 5 As shown, the pulse sampling device further includes a conversion circuit 108, the input terminal of which is connected to the gear switching module 102, and the output terminal of which is connected to the signal processing circuit 103.

[0084] The conversion circuit 108 is used to convert the voltage divider signal into a differential signal and output it to the signal processing circuit 103; the signal processing circuit 103 is also used to convert the differential signal into a digital voltage signal.

[0085] In some implementations, the conversion circuit 108 may include a voltage follower circuit and a differential amplifier circuit. The input terminal of the voltage follower circuit is connected to the gear switching module 102, the output terminal of the voltage follower circuit is connected to the input terminal of the differential amplifier circuit, and the output terminal of the differential amplifier circuit is connected to the signal processing circuit 103.

[0086] The voltage follower circuit may include an operational amplifier for voltage following, which can provide a high input impedance and avoid the influence of a small input impedance on the voltage division of the gear switching circuit; the differential amplifier circuit may employ a differential amplifier to convert the input single-ended signal into a differential amplified signal for transmission to the signal processing circuit 103. Here, converting the input single-ended signal into a differential amplified signal can amplify only the differential mode signal containing valid information to avoid common-mode interference.

[0087] Optionally, the signal conversion circuit (e.g., AD conversion circuit) can also provide a DC bias of 1 / 2 VCC (the power supply voltage of the AD conversion chip) to the conversion circuit 108. By superimposing a bias of 1 / 2 VCC on the signal, the signal that originally fluctuated outside the range of the AD conversion chip can be shifted upward as a whole, ensuring that the signal falls completely into the measurement window of the AD conversion chip.

[0088] In one possible implementation, the conversion circuit 108 may also include an anti-aliasing processing circuit. The input terminal of the anti-aliasing processing circuit can be connected to the output terminal of the conversion circuit 108, and the output terminal of the anti-aliasing processing circuit is connected to the signal processing circuit 103 for low-pass filtering of the signal to filter out high-frequency noise.

[0089] The sampling module 101 is the entry point for pulse signals into the pulse sampling device, and its performance directly affects the quality of signal transmission.

[0090] In one possible implementation, the sampling module 101 includes a coaxial connector for receiving the sampled voltage signal and transmitting the sampled voltage signal to the target gear switching circuit.

[0091] The structural design of the inner and outer conductors and shielding layer of the coaxial connector can achieve good impedance matching, reduce signal reflection, and at the same time, the shielding layer can effectively block external electromagnetic interference, ensuring that the sampled voltage signal is transmitted to the target gear switching circuit completely and without distortion.

[0092] In one possible implementation, the sampling module 101 may also include a transient voltage suppressor (TVS), one end of which is connected to the output of the coaxial connector and the other end is grounded, which can suppress the damage to the circuit caused by transient voltage changes.

[0093] The voltage division effect of the target gear switching circuit on the sampled voltage signal is a key factor in determining the sampling accuracy. By reasonably designing the gear switching circuit, flexible voltage division can be achieved in conjunction with the gear switch.

[0094] In one possible implementation, another coaxial connector can be provided to receive a sampled current signal characterizing the output pulse current information. This sampled current signal is in voltage form and can be transmitted through a gear shifting circuit with the same structure as the gear shifting module 102. The target gear shifting circuit can be determined based on the magnitude of the pulse current. Alternatively, a fixed target gear shifting circuit can be used for transmission of the sampled current signal. Of course, the sampled current signal can also be transmitted using an additional fixed sampling channel; this application does not limit this. After the sampled current signal is output from the target gear shifting circuit or sampling channel, it can sequentially pass through the conversion circuit 108 and the signal processing circuit 103 before entering the controller 104.

[0095] In related technologies, if the pulse sampling device continues to work when the pulse output device stops outputting pulses, it will consume a lot of power. At the same time, if the sampling period and the pulse output period cannot be accurately synchronized, valid pulse signals may be missed, resulting in incomplete sampling.

[0096] In some embodiments, such as Figure 6 As shown, the pulse sampling device further includes a synchronous trigger circuit 109 connected to the controller 104. The synchronous trigger circuit 109 is used to receive a control signal, which is used to indicate the start or end of sampling output pulse.

[0097] The controller 104 is also used to start and / or stop sampling the digital signal based on the control signal.

[0098] The control signal is high when the pulse output device outputs a pulse and low when the pulse output device stops outputting pulses. Considering the time delay, the control signal can start being high a short time before the pulse output device outputs a pulse and be low a short time after the pulse output device stops outputting pulses. The controller 104 receives the control signal through the synchronous trigger circuit 109 to precisely control the timing of sampling start and stop, ensuring that only valid pulse signals are collected, reducing power waste, and improving sampling efficiency and data quality. In addition, the pulse output device can transmit pulse trains, pulse groups (multiple pulse trains), and pulse sequences (multiple pulse groups) depending on the tissue to be ablated or the patient's condition. The controller 104 can pause sampling during the interval between adjacent pulse trains or pulse groups based on the received control signal, thereby achieving segmented sampling of the high-voltage pulse signal and solving the problem of insufficient sampling depth in existing PICO acquisition modules. It is understandable that the output voltages of adjacent pulse trains or pulse groups may be different. The controller 104 can receive control signals, pause sampling during the interval between adjacent pulse trains or pulse groups, determine the target gear switching circuit based on the output voltage of the pulse, and switch the target gear switching circuit by controlling the corresponding gear switch.

[0099] The synchronous trigger circuit 109 may include a fiber optic input interface with a data transmission rate of 50 Mbps and a photoelectric conversion circuit. The fiber optic input interface is used to receive control signals in optical form and transmit them to the controller 104 through the photoelectric conversion circuit. In some embodiments, the controller 104 is also used to control the voltage of the output pulse of the pulse output device based on the operating parameters.

[0100] The controller 104 controls the voltage of the electrical pulses output by the pulse output device based on the operating parameters input by the controller.

[0101] Based on the sampled pulse voltage information and the operating parameters input by the controller, the controller 104 can perform feedback adjustment on the output voltage of the pulse output device to ensure that the pulse voltage is always stable within the target range and improve the accuracy of the output voltage.

[0102] The stability of the power supply to the pulse sampling device is fundamental to ensuring its continuous operation. In industrial or medical settings, sudden power outages are common. If the device stops working immediately after a power outage, the unsaved sampling data in the controller 104 will be lost, and voltage fluctuations at the moment of power failure may also cause circuit malfunctions.

[0103] In one possible implementation, such as Figure 7 and Figure 8 As shown, the pulse sampling device also includes a power supply circuit 110, which includes a power input port, a first voltage conversion circuit, a capacitor charging and discharging circuit, and a second voltage conversion circuit.

[0104] The output terminal of the power input port is connected to the input terminal of the first voltage conversion circuit. The output terminal of the first voltage conversion circuit is connected to the input terminal of the capacitor charging and discharging circuit and the controller. The output terminal of the capacitor charging and discharging circuit is connected to the controller and the input terminal of the second voltage conversion circuit. The output terminal of the second voltage conversion circuit is connected to the controller.

[0105] The first voltage conversion circuit is used to convert the voltage output from the power input port into a first supply voltage and supply power to the controller;

[0106] The capacitor charging and discharging circuit is used to charge the capacitor according to the first power supply voltage, and output the first power supply voltage to the second voltage conversion circuit after charging is completed.

[0107] The second voltage conversion circuit is used to convert the first supply voltage into the second supply voltage and supply power to the controller;

[0108] The capacitor charging and discharging circuit is also used to supply power to the controller and the second voltage conversion circuit when there is no output voltage at the power input port.

[0109] The first voltage conversion circuit transforms the voltage input at the power input port (e.g., 48V) into a first supply voltage (e.g., 12V). This first supply voltage supplies power to the controller, while simultaneously charging the capacitor in the capacitor charging / discharging circuit. After charging, the capacitor charging / discharging circuit provides a 12V power supply voltage to the power input terminal of the controller 104. The second voltage conversion circuit then transforms this first supply voltage into a second supply voltage (e.g., 5V, 3.3V, or a lower voltage), thereby supplying power to other ports of the controller 104 or peripheral circuits. When the power input port is not powered, the capacitor releases its stored energy. This energy provides the first supply voltage to the controller 104 and also briefly supplies power to the second voltage conversion circuit. Based on the released energy, the second voltage conversion circuit can then provide a brief second supply voltage to the controller 104, ensuring that the controller 104 can operate with both the first and second supply voltages provided by the capacitor. This allows for data saving, execution of shutdown protection procedures, and prevention of data loss and equipment damage.

[0110] In one possible implementation, based on the same inventive concept, this application also provides an ablation device, which includes the pulse sampling device provided in any embodiment of this application. Therefore, the ablation device has the technical features of the pulse sampling device provided in the embodiments of this application and can achieve the beneficial effects of the pulse sampling device provided in the embodiments of this application. The similarities can be referred to the above description of the pulse sampling device provided in the embodiments of this application, and will not be repeated here.

[0111] It should be noted that, in this document, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such a process, method, article, or apparatus. Unless otherwise specified, an element defined by the phrase "comprising one..." does not exclude the presence of other identical elements in the process, method, article, or apparatus that includes that element.

[0112] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of indicated technical features. Therefore, a feature defined as "first" or "second" may explicitly or implicitly include at least one of the stated features. In the description of the embodiments of this application, "multiple" means at least two, such as two, three, etc., unless otherwise explicitly specified. It should be noted that "first," "second," etc., are used to distinguish similar objects and are not necessarily used to describe a specific order or sequence.

[0113] It should be understood that the phrase "some embodiments" throughout the specification means that a particular feature, structure, or characteristic related to an embodiment is included in at least one embodiment of this application. Therefore, "some embodiments" appearing throughout the specification does not necessarily refer to the same embodiment. Furthermore, these particular features, structures, or characteristics may be combined in any suitable manner in one or more embodiments without conflict.

[0114] In this article, the term "and / or" is merely a description of the relationship between related objects, indicating that there can be three relationships. For example, A and / or B can represent three situations: A exists alone, A and B exist simultaneously, and B exists alone.

[0115] In the description of the embodiments of this application, it should be noted that, unless otherwise explicitly specified and limited, the terms "connected" or "linked" should be interpreted broadly. For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection, an electrical connection, or a connection that allows communication between the components; it can be a direct connection or an indirect connection through an intermediate medium; it can be the internal communication between two components or the interaction between two components. Those skilled in the art can understand the specific meaning of the above terms in this application according to the specific circumstances.

[0116] The above description is merely a preferred embodiment of this application and is not intended to limit the scope of patent protection of this application. Any equivalent structural transformations made based on the content of this application's specification and drawings, or direct or indirect applications in other related technical fields, are similarly included within the scope of patent protection of this application.

Claims

1. A pulse sampling device, characterized in that, The pulse sampling device is used for sampling and processing the output pulse of the pulse output device, the pulse sampling device comprising: A sampling module is used to sample the output pulse to obtain a sampled voltage signal, and to output the sampled voltage signal; A gear shifting module is electrically connected to the sampling module. The gear shifting module includes at least one gear shifting circuit, which, upon receiving a gear shifting signal, uses a target gear shifting circuit to divide the sampled voltage signal to output a divided voltage signal. The at least one gear shifting circuit includes the target gear shifting circuit, and the at least one gear shifting circuit is connected in parallel. A signal processing circuit, which is electrically connected to the gear shifting module, is used to convert the voltage divider signal into a digital voltage signal. The controller is connected to the gear shifting module and the signal processing circuit respectively, and is used to acquire operating parameters, determine the target gear shifting circuit in the gear shifting module based on the operating parameters, and generate the gear shifting signal. The operating parameters are used to indicate the voltage of the output pulse. The controller is also used to sample the digital voltage signal.

2. The pulse sampling device according to claim 1, characterized in that, The pulse sampling device further includes: An electro-optical conversion circuit is used to receive an electrical signal containing the operating parameters and convert the electrical signal into an optical signal; A photoelectric conversion circuit, connected to the controller, is used to convert the optical signal into an electrical signal containing the operating parameters and send it to the controller; The optical fiber module is disposed between the electro-optical conversion circuit and the photoelectric conversion circuit, and is used to receive the optical signal and transmit it to the photoelectric conversion circuit.

3. The pulse sampling device according to claim 1, characterized in that, Each of the gear shifting circuits includes a gear switch; The controller is specifically used to: determine the target gear shifting circuit in the gear shifting module based on the operating parameters and the first mapping relationship, and generate the gear shifting signal; The target gear shifting circuit includes a gear switch that is turned on after receiving the gear shifting signal.

4. The pulse sampling device according to claim 3, characterized in that, Each of the gear shifting circuits further includes a first voltage divider circuit and a second voltage divider circuit; The input terminal of the first voltage divider circuit is connected to the sampling module, the output terminal of the first voltage divider circuit is connected to the input terminal of the gear switch, and the output terminal of the gear switch is connected to the signal processing circuit; the input terminal of the second voltage divider circuit is connected to the output terminal of the first voltage divider circuit, and the output terminal of the second voltage divider circuit is grounded. Alternatively, the input terminal of the first voltage divider circuit is connected to the sampling module, the output terminal of the first voltage divider circuit is connected to the input terminal of the gear switch, the output terminal of the gear switch is connected to the signal processing circuit and the input terminal of the second voltage divider circuit respectively, and the output terminal of the second voltage divider circuit is grounded.

5. The pulse sampling device according to claim 4, characterized in that, Both the first voltage divider circuit and the second voltage divider circuit include resistors and capacitors connected in parallel.

6. The pulse sampling device according to claim 1, characterized in that, The pulse sampling device further includes a conversion circuit, the input of which is connected to the gear switching module, and the output of which is connected to the signal processing circuit. The conversion circuit is used to convert the voltage divider signal into a differential signal and output it to the signal processing circuit; the signal processing circuit is also used to convert the differential signal into a digital voltage signal.

7. The pulse sampling device according to claim 1, characterized in that, The sampling module includes a coaxial connector, which is used to receive the sampling voltage signal and transmit the sampling voltage signal to the target gear switching circuit.

8. The pulse sampling device according to claim 7, characterized in that, The sampling module also includes a transient voltage suppressor, the input of which is connected to the output of a coaxial connector, and the output of which is grounded.

9. The pulse sampling device according to claim 1, characterized in that, The controller is also used to control the voltage of the output pulse of the pulse output device based on the operating parameters.

10. The pulse sampling device according to claim 1, characterized in that, The pulse sampling device also includes a power supply circuit, which includes a power input port, a first voltage conversion circuit, a capacitor charging and discharging circuit, and a second voltage conversion circuit. The output terminal of the power input port is connected to the input terminal of the first voltage conversion circuit. The output terminal of the first voltage conversion circuit is connected to the input terminal of the capacitor charging and discharging circuit and the controller. The output terminal of the capacitor charging and discharging circuit is connected to the controller and the input terminal of the second voltage conversion circuit. The output terminal of the second voltage conversion circuit is connected to the controller. The first voltage conversion circuit is used to convert the voltage output from the power input port into a first supply voltage and supply power to the controller; The capacitor charging and discharging circuit is used to charge the capacitor according to the first power supply voltage, and output the first power supply voltage to the second voltage conversion circuit after charging is completed. The second voltage conversion circuit is used to convert the first supply voltage into a second supply voltage and supply power to the controller; The capacitor charging and discharging circuit is also used to supply power to the controller and the second voltage conversion circuit when there is no output voltage at the power input port.

11. A tissue ablation device, characterized in that, It includes a pulse output device and a pulse sampling device as described in any one of claims 1 to 9.

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