A new type of pressurized filtration device for pharmaceutical intermediates

Abstract

The utility model belongs to the field of medicine production technology, and disclose a kind of pressurized filtration device for novel drug intermediate, including main body shell, the raw material bucket is fixedly connected in the top of main body shell, the discharge passage is established in the lower side both ends of main body shell, the filter assembly is arranged in the middle part of main body shell, the pressurized pump connecting port is established in the top of main body shell, the motor is fixedly connected in the bottom of main body shell;Wherein, the filter assembly includes support swivel rod, by being provided with first filter plate and second filter plate, by support swivel rod through fixed push block and movable push block resistance, second filter plate and first filter plate shake, so that raw material is scattered on filter plate, increase filter area, make impurity be shaken off from filter surface simultaneously, avoid to block filter screen surface, to this end complete the filtration of raw material, improve the overall filtration effect, avoid the problem of raw material accumulation simultaneously.

Description

Technical Field

[0001] This utility model belongs to the field of pharmaceutical production technology, specifically a new pressure filtration device for pharmaceutical intermediates. Background Technology

[0002] Pharmaceutical intermediates are intermediate chemicals generated during the synthesis of chemical drugs and belong to fine chemical products. They are the core link connecting basic chemical raw materials and the final drug (active pharmaceutical ingredient or formulation). The production of almost all chemical drugs requires intermediates. For example, the synthesis of active pharmaceutical ingredients (APIs) such as antibiotics, antitumor drugs, and antiviral drugs requires multiple chemical reactions to generate intermediates with different structures, which are then further processed into APIs and finally made into formulations. These pharmaceutical intermediates need to be filtered during their preparation.

[0003] Patent CN218357799U discloses a multi-stage pressure filtration device for pharmaceutical intermediates, comprising a housing and a door. An inlet is located on the left end of the upper surface of the housing, and a pressure pump is located in the middle of the upper surface of the housing. The aforementioned patent, through the pressure pump and the inclined feeding plate, enables the pharmaceutical intermediates to be rapidly fed under the action of the inclined feeding plate, and prevents clogging during feeding, thereby promoting the feeding process of the pharmaceutical intermediates.

[0004] In this scheme, the pharmaceutical intermediate is conveyed from the middle, making contact with the filter screen. This causes the raw material to accumulate in the middle of the filter screen, resulting in a small contact area between the filter screen and the pharmaceutical intermediate. Furthermore, the accumulated raw material cannot disperse, affecting the overall filtration effect. Therefore, a novel pressure filtration device for pharmaceutical intermediates is proposed. Utility Model Content

[0005] To address the problems mentioned in the background section, this invention provides a novel pressure filtration device for pharmaceutical intermediates.

[0006] To achieve the above objectives, this utility model provides the following technical solution: a novel pressure filtration device for pharmaceutical intermediates, comprising a main shell, a raw material tank fixedly connected to the top of the main shell, discharge channels opened at both ends of the lower side of the main shell, a filter assembly provided in the middle of the main shell, a pressure pump connection port opened at the top of the main shell, and a motor fixedly connected to the bottom of the main shell; The filter assembly includes a support rod, with a feeding block fixedly connected to the top of the support rod, and the bottom of the support rod penetrating the bottom of the main body shell and fixedly connected to the motor output end.

[0007] Preferably, the bottom of the inner wall of the main body shell is a sloping surface that slopes downward from the middle to both sides, the discharge channel is located at the lowest point of the sloping surface at the bottom of the main body shell, the feeding block is rotatably connected inside the channel connecting the raw material barrel and the main body shell, and a pressure pump is externally connected to the pressure pump connection port.

[0008] Preferably, a guide plate is fixedly connected to the upper end of the support rod, the guide plate is in the shape of a downwardly opening trumpet, and a first filter plate and a second filter plate are provided in the middle of the support rod, both of which are slidably connected to the main body shell.

[0009] Preferably, the middle part of the first filter plate is sleeved on the outer side of the middle part of the second filter plate, the first filter plate and the second filter plate are frustum-shaped with opposite orientations, a sliding bracket is fixedly connected to the middle part of the second filter plate, and a spring is fixedly connected to the top of the sliding bracket.

[0010] Preferably, the sliding bracket is arranged in a ring in the middle of the second filter plate, the sliding bracket is slidably connected to the first filter plate, and the second filter plate is rotatably connected to the support rod.

[0011] Preferably, a movable push block is rotatably connected to the middle of the supporting rotating rod, and a fixed push block is fixedly connected to the middle of the supporting rotating rod. Both the movable push block and the fixed push block have arc-shaped protrusions on their sides that are close to each other.

[0012] Preferably, the movable push block is rotatably connected inside the second filter plate, and the top of the movable push block is fixedly connected to the second filter plate by a spring.

[0013] Compared with the prior art, the beneficial effects of this utility model are as follows: This utility model features a first filter plate and a second filter plate. A supporting rotating rod, through the contact between a fixed push block and a movable push block, causes the second filter plate and the first filter plate to vibrate, which disperses the raw material on the filter plates, increasing the filtration area. At the same time, it shakes impurities off the filter surface, preventing clogging of the filter screen. This completes the filtration of the raw material, improves the overall filtration effect, and avoids the problem of raw material accumulation. Attached Figure Description

[0014] Figure 1 This is a schematic diagram of the overall structure of this utility model; Figure 2 This is a cross-sectional view of the middle section of this utility model; Figure 3 This is a schematic diagram of the overall filter assembly of this utility model; Figure 4 This is a schematic diagram of the connection between the first filter plate and the second filter plate of this utility model.

[0015] In the picture: 1. Main body shell; 2. Raw material barrel; 3. Discharge channel; 4. Filter assembly; 41. Support rod; 42. Feeding block; 43. Guide plate; 44. First filter plate; 45. Second filter plate; 46. Sliding bracket; 47. Movable push block; 48. Fixed push block; 5. Pressure pump connection port; 6. Motor. Detailed Implementation

[0016] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0017] like Figures 1 to 4 As shown, this utility model provides a new pressure filtration device for pharmaceutical intermediates, including a main shell 1, a raw material tank 2 fixedly connected to the top of the main shell 1, discharge channels 3 opened at both ends of the lower side of the main shell 1, a filter assembly 4 arranged in the middle of the main shell 1, a pressure pump connection port 5 opened at the top of the main shell 1, and a motor 6 fixedly connected to the bottom of the main shell 1. The filter assembly 4 includes a support rod 41, with a feeding block 42 fixedly connected to the top of the support rod 41, and the bottom of the support rod 41 penetrating the bottom of the main body shell 1 and fixedly connected to the output end of the motor 6.

[0018] like Figures 1 to 3 As shown, the bottom of the inner wall of the main body shell 1 is a slope that slopes downward from the middle to both sides. The discharge channel 3 is located at the lowest point of the bottom slope of the main body shell 1. The feeding block 42 is rotatably connected to the inside of the channel connecting the raw material barrel 2 and the main body shell 1. The pressure pump connection port 5 is connected to a pressure pump.

[0019] The above scheme is adopted as follows: by setting the raw material tank 2, a sufficient amount of raw material can be added at one time for filtration, which makes it easy to control the amount of raw material. At the same time, the setting of the feeding block 42 allows the raw material to be conveyed downward evenly by rotating the feeding block 42, avoiding excessive local material conveying and accumulation on the first filter plate 44 and the second filter plate 45. The setting of the discharge channel 3 is used to discharge the raw material in a timely manner, avoiding the accumulation of raw material at the bottom of the main body shell 1. The setting of the pressure pump connection port 5 is used to pressurize the inside of the main body shell 1 to improve the filtration effect.

[0020] like Figures 2 to 4As shown, a guide plate 43 is fixedly connected to the upper end of the support rod 41. The guide plate 43 is in the shape of a downwardly opening trumpet. A first filter plate 44 and a second filter plate 45 are provided in the middle of the support rod 41. Both the first filter plate 44 and the second filter plate 45 are slidably connected to the main body shell 1. The first filter plate 44 is sleeved on the outer side of the middle part of the second filter plate 45. The first filter plate 44 and the second filter plate 45 are frustum-shaped with opposite orientations. A sliding bracket 46 is fixedly connected to the middle part of the second filter plate 45, and a spring is fixedly connected to the top of the sliding bracket 46. The sliding bracket 46 is arranged in a ring in the middle of the second filter plate 45. The sliding bracket 46 is slidably connected to the first filter plate 44, and the second filter plate 45 is rotatably connected to the support rod 41.

[0021] The above scheme employs a guide plate 43 to guide the raw material, allowing it to contact the first filter plate 44 from the outside. This causes the filter holes on the surface of the first filter plate 44 to cover the material layer by layer from the outside in. Simultaneously, any raw material that cannot be filtered in time on the surface of the first filter plate 44 is shaken onto the surface of the second filter plate 45 for further filtration. Due to the pressure exerted on the interior of the main body shell 1 by the pressure pump connection port 5, the second filter plate 45 has a higher filtration efficiency than the first filter plate 44, allowing the raw material filtered by the first filter plate 44 to pass through the second filter plate 45 quickly. The inclined arrangement of the first and second filter plates 44 and 45 increases the filtration area, further improving the filtration efficiency.

[0022] like Figures 2 to 4 As shown, a movable push block 47 is rotatably connected to the middle of the support rod 41, and a fixed push block 48 is fixedly connected to the middle of the support rod 41. Both the movable push block 47 and the fixed push block 48 have arc-shaped protrusions on their sides that are close to each other. The movable push block 47 is rotatably connected inside the second filter plate 45, and the top of the movable push block 47 is fixedly connected to the second filter plate 45 by a spring.

[0023] The above solution is adopted: by setting the movable push block 47 and the fixed push block 48, the first filter plate 44 and the second filter plate 45 can shake with the rotation of the support rod 41, so as to spread the raw material on the first filter plate 44 and the second filter plate 45 and ensure the filtration efficiency of the first filter plate 44 and the second filter plate 45.

[0024] Working principle and usage process of this utility model: During operation, raw materials are added into the raw material tank 2, and then the motor 6 is started. The motor 6 drives the support rotating rod 41 to rotate, which in turn drives the feeding block 42 and the fixed push block 48 to rotate. When the feeding block 42 rotates, it will evenly discharge the raw materials inside the raw material tank 2 towards the guide plate 43. After the raw materials come into contact with the guide plate 43, they are guided by the guide plate 43 to the upper end of the first filter plate 44 and spread out to contact the first filter plate 44. At this time, the fixed push block 48 will simultaneously abut against the movable push block 47, causing the movable push block 47 to push the second filter plate 45 up and down through the spring 2. At the same time, the second filter plate 45 will pass through the spring 47. The spring synchronously drives the first filter plate 44 to shake, so that when the raw material comes into contact with the first filter plate 44, the impurities that cannot pass through the first filter plate 44 will move towards the center along the shaking first filter plate 44 until they are shaken off from the center of the first filter plate 44 to the top of the second filter plate 45. At this time, the raw material falling on the second filter plate 45 will be subjected to pressure by the main body shell 1, so that the raw material can quickly pass through the second filter plate 45. At the same time, the raw material and impurities will move along the second filter plate 45, so that the raw material is filtered to the bottom of the main body shell 1, and the impurities remain on the top of the second filter plate 45, thereby completing the filtration of the raw material.

[0025] It should be noted that, in this document, relational terms such as "first" and "second" are used only to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such process, method, article, or apparatus.

[0026] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A novel pressure filtration device for pharmaceutical intermediates, comprising a main body shell (1), characterized in that: The main body shell (1) is fixedly connected to the top of the raw material barrel (2), the main body shell (1) is provided with discharge channels (3) at both ends of the lower side, the main body shell (1) is provided with a filter assembly (4) in the middle, the main body shell (1) is provided with a pressure pump connection port (5) at the top, and the main body shell (1) is fixedly connected to the bottom of the main body shell (1). The filter assembly (4) includes a support rod (41), the top of which is fixedly connected to a feeding block (42), and the bottom of which penetrates the bottom of the main body shell (1) and is fixedly connected to the output end of the motor (6).

2. The pressure filtration device for novel pharmaceutical intermediates according to claim 1, characterized in that: The bottom of the inner wall of the main body shell (1) is a slope that slopes downward from the middle to both sides. The discharge channel (3) is located at the lowest point of the bottom slope of the main body shell (1). The feeding block (42) is rotatably connected inside the channel connecting the raw material barrel (2) and the main body shell (1). The pressure pump connection port (5) is connected to a pressure pump.

3. The pressure filtration device for novel pharmaceutical intermediates according to claim 1, characterized in that: The upper end of the support rod (41) is fixedly connected to a guide plate (43), which is in the shape of a downward-opening trumpet. The middle part of the support rod (41) is provided with a first filter plate (44) and a second filter plate (45), both of which are slidably connected to the main body shell (1).

4. The pressure filtration device for novel pharmaceutical intermediates according to claim 3, characterized in that: The first filter plate (44) is sleeved on the outside of the middle of the second filter plate (45). The first filter plate (44) and the second filter plate (45) are frustum-shaped with opposite orientations. A sliding bracket (46) is fixedly connected to the middle of the second filter plate (45), and a spring is fixedly connected to the top of the sliding bracket (46).

5. The pressure filtration device for novel pharmaceutical intermediates according to claim 4, characterized in that: The sliding bracket (46) is arranged in a ring in the middle of the second filter plate (45). The sliding bracket (46) is slidably connected to the first filter plate (44), and the second filter plate (45) is rotatably connected to the support rod (41).

6. The pressure filtration device for novel pharmaceutical intermediates according to claim 3, characterized in that: The middle part of the support rod (41) is rotatably connected to a movable push block (47), and the middle part of the support rod (41) is fixedly connected to a fixed push block (48). The movable push block (47) and the fixed push block (48) are both provided with arc-shaped protrusions on their sides that are close to each other.

7. The pressure filtration device for novel pharmaceutical intermediates according to claim 6, characterized in that: The movable push block (47) is rotatably connected inside the second filter plate (45), and the top of the movable push block (47) is fixedly connected to the second filter plate (45) by a spring.

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