A screening device for producing pharmaceutical grade PVP
Patent Information
- Application Number
- CN202522099764.7
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-09-29
- Publication Date
- 2026-09-22
- Estimated Expiration
- 2035-09-29
AI Technical Summary
[0004]本实用新型提供了一种生产医药级PVP用筛分装置，解决了以上所述的筛网容易出现堵塞的情况，会造成物料交叉污染，影响后续批次产品的纯度与质量一致性，也会降低筛分效率的结构技术问题
[0006]本实用新型的有益效果是：清洗圆筒主要是起到了可以便于存储水流的作用，设置的超声波发生器是一个具有特定谐振频率和阻抗的器件，发生器内部的匹配电路会调节输出信号的频率和相位，使其与换能器的固有谐振频率一致，实现阻抗匹配，这样可以便于让压电换能器大功率的被传输，压电换能器通过逆压电效应让微观的伸缩变形被叠加起来，就形成了换能器前端面宏观的高频机械振动。这个振动的频率与输入电信号的频率完全相同，即产生了超声波，从而可以利用超声波来清洗筛选筒内部的一号筛网和二号筛网以及三号筛网，输送管可以便于外接水流到清洗圆筒的内部，排污管可以便于清洗后的污水排出，一号阀门可以便于对输送管的内部流量控制，二号阀门可以便于对排污的内部流量控制，支撑板可以便于支撑液压伸缩杆，液压伸缩杆可以让移动板呈上下移动，移动板可以支撑弹簧，弹簧可以便于支撑连接板，连接板可以支撑振动筛选组件，振动筛选组件主要是可以便于振动来完成筛分。
Smart Images
Figure CN224778813U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of pharmaceutical-grade PVP screening technology, and in particular to a screening device for producing pharmaceutical-grade PVP. Background Technology
[0002] Pharmaceutical-grade PVP (polyvinylpyrrolidone) is a pharmaceutical polymer material prepared through high-precision chemical synthesis and strict purification processes. It must meet the standards of the Chinese Pharmacopoeia (CP), the United States Pharmacopeia (USP), and the European Pharmacopoeia (EP), and is widely used in pharmaceutical preparations, medical devices, and the biopharmaceutical field.
[0003] Existing screening devices for pharmaceutical-grade PVP production suffer from a significant technical flaw in practical applications: screen clogging is a common problem. During screening, material particles adhere to the screen or their size closely matches the mesh size, easily clogging the screen surface and mesh, resulting in some material remaining on the screen and unable to pass through smoothly. Most screening devices lack a cleaning mechanism, making it difficult for operators to effectively and thoroughly clean the screen. This clogging and residue problem not only causes cross-contamination of materials, affecting the purity and quality consistency of subsequent batches, but also significantly reduces screening efficiency. Utility Model Content
[0004] This invention provides a screening device for producing pharmaceutical-grade PVP, which solves the structural and technical problems mentioned above, such as the easy clogging of the screen, which causes cross-contamination of materials, affects the purity and quality consistency of subsequent batches of products, and reduces screening efficiency.
[0005] The present invention provides the following solution to the above-mentioned technical problems: A screening device for producing pharmaceutical-grade PVP includes a cleaning cylinder. An ultrasonic generator is installed at the bottom of the cleaning cylinder. Multiple piezoelectric transducers are arranged in a linear equidistant array on the inner bottom surface of the cleaning cylinder. A conveying pipe is installed on one side of the cleaning cylinder, and a valve No. 1 is installed at the top of the conveying pipe. A drain pipe is installed on the other side of the cleaning cylinder, and a valve No. 2 is installed at the top of the drain pipe. Support plates are installed on both sides of the inner surface of the cleaning cylinder. Four hydraulic telescopic rods are installed at the top of each support plate. Two movable plates are connected to the top of two support plates through eight hydraulic telescopic rods. Two springs are installed at the top of each movable plate. Two connecting plates are connected to the top of two movable plates through four springs. A vibrating screening assembly is installed between the opposite sides of each connecting plate.
[0006] The beneficial effects of this utility model are: the cleaning cylinder mainly serves to facilitate the storage of water flow; the ultrasonic generator is a device with a specific resonant frequency and impedance; the matching circuit inside the generator adjusts the frequency and phase of the output signal to match the inherent resonant frequency of the transducer, thus achieving impedance matching. This facilitates the transmission of high power from the piezoelectric transducer; the piezoelectric transducer uses the inverse piezoelectric effect to superimpose microscopic expansion and contraction deformations, thereby forming macroscopic high-frequency mechanical vibrations on the front end of the transducer. The frequency of this vibration is exactly the same as the frequency of the input electrical signal, thus generating ultrasonic waves. These ultrasonic waves can be used to clean the No. 1, No. 2, and No. 3 screens inside the screening cylinder. The conveying pipe facilitates the flow of external water into the cleaning cylinder, and the drain pipe facilitates the discharge of wastewater after cleaning. Valve No. 1 facilitates the internal flow control of the conveying pipe, and valve No. 2 facilitates the internal flow control of the drain. The support plate facilitates the support of the hydraulic telescopic rod, which allows the moving plate to move up and down. The moving plate supports the spring, which in turn supports the connecting plate. The connecting plate supports the vibrating screening assembly, which primarily facilitates screening through vibration.
[0007] Based on the above technical solution, the present invention can be further improved as follows.
[0008] Furthermore, the vibration screening assembly includes a screening cylinder, which is disposed on opposite sides of the two connecting plates.
[0009] The beneficial effects of adopting the above-mentioned further solution are: the screening cylinder can facilitate the screening of pharmaceutical-grade PVP, and a vibration motor can be installed on the outside to complete the vibration screening.
[0010] Furthermore, a No. 1 screen is connected inside the screening cylinder, and a No. 2 screen is provided inside the screening cylinder near the bottom of the No. 1 screen.
[0011] The beneficial effects of adopting the above-mentioned further scheme are: the first screen can first screen the pharmaceutical-grade PVP, and the second screen can facilitate the secondary screening of the pharmaceutical-grade PVP.
[0012] Furthermore, a third screen is provided inside the screening cylinder near the bottom of the second screen, and a feed inlet is provided at the top of the screening cylinder.
[0013] The beneficial effects of adopting the above-mentioned further scheme are: the No. 3 sieve can facilitate the three-stage sieving process of pharmaceutical-grade PVP, and the multiple sieving processes can help improve purity and remove harmful impurities.
[0014] Furthermore, one side of the screening cylinder has three discharge ports arranged in a linear equidistant array.
[0015] The beneficial effect of adopting the above-mentioned further solution is that the discharge port can easily discharge the sieved pharmaceutical-grade PVP.
[0016] Furthermore, a sealed door is rotatably connected to the rear of the cleaning cylinder via a hinge, and a handle is provided on one side of the sealed door.
[0017] The beneficial effects of adopting the above-mentioned further solution are: the sealed door can be easily opened and closed, which makes it convenient for personnel to open and close the cleaning cylinder using the handle, and facilitates personnel to clean and retrieve the materials inside the cleaning cylinder.
[0018] Beneficial effects: By using an ultrasonic generator and a piezoelectric transducer, ultrasonic waves can be used to clean the No. 1, No. 2, and No. 3 screens on the vibrating screening assembly, so that the screen openings can be cleaned and unblocked. This helps to prevent material residue on the screens, minimizes cross-contamination during the next use, and ensures the screening efficiency of the next material.
[0019] The above description is merely an overview of the technical solution of this utility model. In order to better understand the technical means of this utility model and to implement it according to the contents of the specification, the preferred embodiments of this utility model are described in detail below with reference to the accompanying drawings. The specific implementation methods of this utility model are given in detail in the following embodiments and their accompanying drawings. Attached Figure Description
[0020] The accompanying drawings, which are included to provide a further understanding of the present invention and form part of this application, illustrate exemplary embodiments of the present invention and, together with the description thereof, serve to explain the present invention and do not constitute an undue limitation thereof. In the drawings: Figure 1 A perspective view of a screening device for producing pharmaceutical-grade PVP is provided for this utility model; Figure 2 This utility model provides a frontal cross-sectional view of a screening device for producing pharmaceutical-grade PVP. Figure 3 This utility model provides a side sectional view of the screening cylinder structure of a screening device for producing pharmaceutical-grade PVP. Figure 4 This utility model provides a rear view structural diagram of a screening device for producing pharmaceutical-grade PVP.
[0021] Legend: 1. Cleaning cylinder; 2. Ultrasonic generator; 3. Piezoelectric transducer; 4. Conveying pipe; 5. No. 1 valve; 6. Drain pipe; 7. No. 2 valve; 8. Support plate; 9. Hydraulic telescopic rod; 10. Moving plate; 11. Spring; 12. Connecting plate; 13. Vibrating screening assembly; 130. Screening cylinder; 131. No. 1 screen; 132. No. 2 screen; 133. No. 3 screen; 134. Feed inlet; 135. Discharge outlet; 14. Sealed door; 15. Handle. Detailed Implementation
[0022] The following is in conjunction with the appendix Figure 1-4 The principles and features of this utility model are described below. The examples given are for illustrative purposes only and are not intended to limit the scope of this utility model. The utility model is described more specifically in the following paragraphs by way of example with reference to the accompanying drawings. The advantages and features of this utility model will become clearer from the following description and claims. It should be noted that the drawings are in a very simplified form and use non-precise proportions, and are only used to facilitate and clarify the illustration of the embodiments of this utility model. Example
[0023] like Figure 1-4 As shown, this utility model discloses a screening device for producing pharmaceutical-grade PVP, comprising a cleaning cylinder 1, an ultrasonic generator 2 at the bottom of the cleaning cylinder 1, multiple piezoelectric transducers 3 arranged in a linear equidistant array on the inner bottom surface of the cleaning cylinder 1, a conveying pipe 4 on one side of the cleaning cylinder 1, a first valve 5 at the top of the conveying pipe 4, a drain pipe 6 on the other side of the cleaning cylinder 1, a second valve 7 at the top of the drain pipe 6, support plates 8 on both sides of the inner surface of the cleaning cylinder 1, four hydraulic telescopic rods 9 at the top of each support plate 8, two movable plates 10 connected to the top of each support plate 8 by eight hydraulic telescopic rods 9, two springs 11 at the top of each movable plate 10, two connecting plates 12 connected to the top of each movable plate 10 by four springs 11, and a vibrating screening assembly 13 between opposite sides of each connecting plate 12. Example
[0024] like Figure 1-4 As shown, the vibrating screening assembly 13 includes a screening cylinder 130, which is disposed on opposite sides of the two connecting plates 12. A first screen 131 is connected inside the screening cylinder 130. A second screen 132 is disposed inside the screening cylinder 130 near the bottom of the first screen 131. A third screen 133 is disposed inside the screening cylinder 130 near the bottom of the second screen 132. A feed inlet 134 is disposed at the top of the screening cylinder 130.
[0025] In this embodiment, the screening cylinder 130 can facilitate the screening of pharmaceutical-grade PVP. A vibration motor can be installed on the outside to complete the vibration screening. The first screen 131 can first screen the pharmaceutical-grade PVP, the second screen 132 can facilitate the second screening of the pharmaceutical-grade PVP, and the third screen 133 can facilitate the third screening of the pharmaceutical-grade PVP. Multiple screenings can help improve purity and remove harmful impurities. Example
[0026] like Figure 1-4 As shown, the screening cylinder 130 has three discharge ports 135 arranged in a linear equidistant array on one side. The rear of the washing cylinder 1 is connected to a sealing box door 14 by a hinge, and a handle 15 is provided on one side of the sealing box door 14.
[0027] In this embodiment, the discharge port 135 facilitates the discharge of sieved pharmaceutical-grade PVP, and the sealed door 14 facilitates the opening and closing of the cleaning cylinder 1. This allows personnel to easily open and close the cylinder using the handle 15, making it convenient for personnel to clean and retrieve the materials inside the cleaning cylinder 1.
[0028] Working principle: When cleaning the screening cylinder 130 is required, the hydraulic telescopic rod 9 moves the moving plate 10 linearly up and down. The spring 11 and connecting plate 12 on the moving plate 10 allow the screening cylinder 130 to fall to a position with water. First, valve 5 is opened, and valve 7 is closed. Water from the external water supply pipe 4 is delivered to the interior of the cleaning cylinder 1. The water flows through screens 131, 132, and 133 for ultrasonic cleaning. During ultrasonic cleaning, the ultrasonic generator 2, a device with a specific resonant frequency and impedance, has its internal matching circuit adjusting the frequency and phase of the output signal to match the transducer's inherent resonant frequency, achieving impedance matching. This facilitates high-power transmission from the piezoelectric transducer 3. The piezoelectric transducer 3, through the inverse piezoelectric effect, superimposes microscopic expansion and contraction deformations, forming a macroscopic high-frequency mechanical vibration at the transducer's front end. The frequency of this vibration is exactly the same as the frequency of the input electrical signal, thus generating ultrasound. Ultrasonic waves are mechanical waves and must travel through a medium to propagate. Water is the best medium for transmitting ultrasonic energy to the surface of a workpiece. By generating tiny bubbles and then allowing them to burst, dirt is removed. The bursting of these bubbles generates extremely high-speed shock waves. These shock waves directly impact the workpiece surface, acting like countless "microscopic hammers" to crush and shake off the attached dirt. The ultrasonic energy instantly creates a large number of vacuum bubbles in the liquid, and the concentrated energy released when these bubbles collapse achieves efficient and thorough cleaning. This helps prevent material residue from remaining on the surface, minimizing cross-contamination during subsequent use, ensuring efficient screening of materials, and guaranteeing the purity and quality consistency of subsequent batches of products. After cleaning, wastewater can be discharged through drain pipe 6 by opening valve 7.
[0029] The above are merely preferred embodiments of this utility model and are not intended to limit the utility model in any way. Those skilled in the art can readily implement this utility model based on the accompanying drawings and the above description. However, any modifications, alterations, or variations made by those skilled in the art without departing from the scope of the utility model's technical solution, utilizing the disclosed technical content, are equivalent embodiments of this utility model. Furthermore, any equivalent changes, alterations, or variations made to the above embodiments based on the essential technology of this utility model are still within the protection scope of this utility model's technical solution.
Claims
1. A screening device for producing pharmaceutical-grade PVP, comprising a cleaning cylinder (1), characterized in that: An ultrasonic generator (2) is provided at the bottom of the cleaning cylinder (1). Multiple piezoelectric transducers (3) are arranged in a linear equidistant array on the inner bottom surface of the cleaning cylinder (1). A conveying pipe (4) is provided on one side of the cleaning cylinder (1). A valve (5) is provided at the top of the conveying pipe (4). A drain pipe (6) is provided on the other side of the cleaning cylinder (1). A valve (7) is provided at the top of the drain pipe (6). Support plates (8) are provided on both sides of the inner surface of the cleaning cylinder (1). Four hydraulic telescopic rods (9) are provided at the top of each support plate (8). Two moving plates (10) are connected to the top of the two support plates (8) through eight hydraulic telescopic rods (9). Two springs (11) are provided at the top of each moving plate (10). Two connecting plates (12) are connected to the top of the two moving plates (10) through four springs (11). A vibration screening assembly (13) is provided between the opposite sides of each connecting plate (12).
2. The screening device for producing pharmaceutical-grade PVP according to claim 1, characterized in that: The vibration screening assembly (13) includes a screening cylinder (130) which is disposed on opposite sides of two connecting plates (12).
3. The screening device for producing pharmaceutical-grade PVP according to claim 2, characterized in that: The screening cylinder (130) is connected to a first screen (131) inside, and a second screen (132) is provided inside the screening cylinder (130) near the bottom of the first screen (131).
4. A screening device for producing pharmaceutical-grade PVP according to claim 2, characterized in that: The screening cylinder (130) has a No. 3 screen (133) located at the bottom near the No. 2 screen (132) inside, and a feed inlet (134) is located at the top of the screening cylinder (130).
5. A screening device for producing pharmaceutical-grade PVP according to claim 2, characterized in that: The screening cylinder (130) has three discharge ports (135) arranged in a linear equidistant array on one side.
6. A screening device for producing pharmaceutical-grade PVP according to claim 1, characterized in that: The rear of the cleaning cylinder (1) is connected to a sealing box door (14) via a hinge, and a handle (15) is provided on one side of the sealing box door (14).