A drying tray suitable for vacuum drying of tablet formulations

Abstract

This utility model relates to the technical field of auxiliary equipment for pharmaceutical production, and discloses a drying tray suitable for vacuum drying of tablet preparations. The tray includes a tray body, which comprises a base plate and side plates surrounding the base plate. The base plate has a plurality of evenly distributed protrusions and a plurality of ventilation holes, arranged in a crisscross pattern with the protrusions. The drying tray of this utility model, suitable for vacuum drying of tablet preparations, features evenly distributed protrusions and ventilation holes on the base plate. The dense arrangement of the protrusions minimizes direct contact between the tablet preparation and the base plate, while the ventilation holes improve gas flow efficiency, increase air exchange, reduce heat transfer, and shorten processing time.

Description

Technical Field

[0001] This utility model relates to the field of auxiliary equipment technology for pharmaceutical production, specifically to a drying tray suitable for vacuum drying of tablet formulations. Background Technology

[0002] Vacuum drying is a widely used process in the preparation of S-adenosylmethionine disulfonate enteric-coated tablets. One characteristic of S-adenosylmethionine disulfonate raw material is that hydrolysis produces impurities such as adenine. This hydrolysis reaction requires water, and the hydrolysis rate increases significantly with increasing temperature. Vacuum drying shortens the time the drug is exposed to high temperatures.

[0003] Vacuum drying typically uses ordinary rectangular drying trays, usually made of 304 stainless steel. When using conventional trays to hold tablets, gas flow is obstructed at the bottom of the tray, and one side of the tablets is in direct contact with the bottom, which is not conducive to even heating. Some drying trays are perforated to improve gas flow efficiency, but this also results in uneven heating of the tablets due to their contact with the bottom surface. Utility Model Content

[0004] To address the shortcomings of the existing technology, this invention provides a drying tray suitable for vacuum drying of tablet formulations, which reduces direct contact between the tablet formulation and the base plate and improves gas flow efficiency.

[0005] To achieve the above-mentioned technical objectives, the technical solution adopted by this utility model is as follows:

[0006] A drying tray suitable for vacuum drying of tablet formulations includes a tray body, the tray body including a bottom plate and side plates surrounding the outer periphery of the bottom plate, the bottom plate having a plurality of protrusions and a plurality of vent holes evenly distributed, the vent holes and protrusions being arranged in a crisscross pattern.

[0007] As a preferred technical solution, the protrusions are arranged in a matrix, and ventilation holes are provided between adjacent protrusions laterally.

[0008] As a preferred technical solution, the protrusions are arranged in a matrix, and ventilation holes are provided between longitudinally adjacent protrusions.

[0009] As a preferred technical solution, the protrusions are arranged in a matrix, and ventilation holes are provided between adjacent protrusions in the horizontal and vertical directions.

[0010] As a preferred technical solution, the protrusions are arranged in a plum blossom pattern, and the vent holes are arranged in a matrix, with vent holes provided between adjacent protrusions in odd or even rows.

[0011] As a preferred technical solution, the protrusions are arranged in a plum blossom pattern, the vent holes are arranged in a plum blossom pattern, and a vent hole is provided at the center of four adjacent protrusions.

[0012] As a preferred technical solution, the protrusion is cylindrical, the top of the protrusion is hemispherical, and the vent is a circular hole.

[0013] As a preferred technical solution, the diameter of the protrusion is 2-4 mm, the radius of the top of the protrusion is 1-2 mm, the height of the protrusion is 1-4 mm, and the spacing between adjacent protrusions is 4-6 mm; the diameter of the vent hole is 1-2 mm.

[0014] As a preferred technical solution, the diameter of the protrusion is 2mm, the radius of the top of the protrusion is 1mm, the height of the protrusion is 2mm, and the diameter of the vent hole is 1mm.

[0015] The beneficial effects of this utility model are as follows:

[0016] The present invention relates to a drying tray for vacuum drying of tablet preparations. The tray has raised protrusions and vent holes evenly arranged on the bottom plate. The dense arrangement of the protrusions allows the tablet preparation to have as little direct contact with the bottom plate as possible, while the vent holes can improve gas flow efficiency, increase air exchange, reduce heat transfer, and shorten the process time.

[0017] The present invention relates to a drying tray suitable for vacuum drying of tablet preparations. The raised arrangement and shape can reduce surface wear of tablet preparations and facilitate the laying and pouring of tablet preparations after drying. Attached Figure Description

[0018] To more clearly illustrate the technical solutions of the embodiments of this application, the accompanying drawings used in the embodiments will be briefly introduced below. It should be understood that the following drawings only show some embodiments of this application and should not be regarded as a limitation of the scope. For those skilled in the art, other related drawings can be obtained based on these drawings without creative effort.

[0019] Figure 1 This is a schematic diagram of the overall structure of an embodiment of the present utility model;

[0020] Figure 2 This is a schematic diagram of one embodiment of the arrangement of protrusions and ventilation holes;

[0021] Figure 3 This is a schematic diagram of another embodiment of the arrangement of protrusions and vent holes;

[0022] Figure 4 This is a partial sectional view of the base plate.

[0023] Reference numerals: 1-bottom plate, 2-side plate, 11-protrusion, 12-ventilation hole. Detailed Implementation

[0024] To make the objectives, technical solutions, and advantages of the embodiments of this application clearer, the technical solutions of the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this application, not all embodiments. The components of the embodiments of this application described and shown in the accompanying drawings can be arranged and designed in various different configurations. Therefore, the following detailed description of the embodiments of this application provided in the accompanying drawings is not intended to limit the scope of the claimed application, but merely represents selected embodiments of this application. All other embodiments obtained by those skilled in the art based on the embodiments of this application without creative effort are within the scope of protection of this application.

[0025] A drying tray suitable for vacuum drying of tablet formulations, such as Figures 1-4 As shown, the device includes a disc body, which includes a base plate 1 and side plates 2 surrounding the outer periphery of the base plate 1. The base plate 1 has a number of protrusions 11 and a number of ventilation holes 12 evenly distributed on it, and the ventilation holes 12 and the protrusions 11 are arranged in a crisscross pattern.

[0026] In one embodiment, such as Figure 2 As shown, the protrusions 11 are arranged in a matrix, and ventilation holes 12 are provided between adjacent protrusions 11 laterally, such as... Figure 2 (a); or ventilation holes 12 are provided between longitudinally adjacent protrusions 11, such as Figure 2 (b) More preferably, ventilation holes 12 are provided between adjacent protrusions 11 in both the transverse and longitudinal directions, such as... Figure 2 (c)

[0027] In another embodiment, the protrusions 11 are arranged in a quincunx pattern, and the vent holes 12 are arranged in a matrix, with vent holes 12 provided between adjacent protrusions 11 in odd or even rows, such as... Figure 3 (a) Figure 3 As shown in (b). More preferably, the protrusions 11 are arranged in a quincunx pattern, and the vent holes 12 are also arranged in a quincunx pattern, with a vent hole 12 located at the center of four adjacent protrusions 11, as shown in (b). Figure 3 As shown in (c).

[0028] In one specific embodiment, the protrusion 11 is cylindrical, the top of the protrusion 11 is hemispherical, the diameter of the protrusion 11 is 2-4 mm, the radius of the top of the protrusion 11 is 1-2 mm, the height of the protrusion 11 is 1-4 mm, and the spacing between adjacent protrusions 11 is 4-6 mm; the diameter of the vent hole 12 is 1-2 mm.

[0029] To ensure drying efficiency, the diameter of the vent 12 should be as large as possible to allow airflow to pass through quickly. However, if the diameter of the vent 12 is too small, the processing difficulty will increase, while if the size of the vent is too large, it will affect the arrangement of the protrusions 11. Therefore, the diameter of the vent 12 is preferably 1 mm, 1.5 mm, or 2 mm.

[0030] The distance between adjacent protrusions 11 affects the cleaning difficulty. A smaller distance makes the tablets easier to lay and pour (less likely to get stuck between protrusions), but also increases cleaning difficulty. Conversely, a large distance may cause tablets to fall between protrusions, affecting placement. In this invention, the distance between adjacent protrusions 11 is set to 4-6 mm, suitable for tablets with at least two dimensions (length, width, and height) greater than 6 mm, and also facilitates cleaning. The preferred height of the protrusions is 1 mm, 2 mm, 3 mm, or 4 mm. To simplify processing and improve protrusion quality, a height of 2 mm is chosen. The smoothness of the protrusion top affects the surface quality of the tablet. Polishing the protrusion top surface prevents scratches. A protrusion radius of 1-2 mm will not scratch the tablet. Since the tablet undergoes subsequent coating, even slight scratches will not ultimately affect product quality. Therefore, to simplify processing, the surface of the protrusion can be left unpolished.

[0031] The present invention relates to a drying tray for vacuum drying of tablet preparations. The tray has raised protrusions and vent holes evenly arranged on the bottom plate. The dense arrangement of the protrusions allows the tablet preparation to have as little direct contact with the bottom plate as possible, while the vent holes can improve gas flow efficiency, increase air exchange, reduce heat transfer, and shorten the process time.

[0032] Of course, there may be other embodiments of this utility model. Without departing from the spirit and essence of this utility model, those skilled in the art can make various corresponding changes and modifications based on this utility model, but these corresponding changes and modifications should all fall within the protection scope of the appended claims of this utility model.

Claims

1. A drying tray suitable for vacuum drying of tablet formulations, comprising a tray body, characterized in that: The disc body includes a base plate (1) and a side plate (2) surrounding the outer periphery of the base plate (1). The base plate (1) is evenly distributed with a number of protrusions (11) and a number of ventilation holes (12). The ventilation holes (12) and the protrusions (11) are arranged in a crisscross pattern. The protrusions (11) are cylindrical, and the top of the protrusions (11) is hemispherical. The ventilation holes (12) are round holes.

2. The drying tray for vacuum drying of tablet formulations according to claim 1, characterized in that: The protrusions (11) are arranged in a matrix, and ventilation holes (12) are provided between adjacent protrusions (11) in the lateral direction.

3. The drying tray for vacuum drying of tablet formulations according to claim 1, characterized in that: The protrusions (11) are arranged in a matrix, and ventilation holes (12) are provided between longitudinally adjacent protrusions (11).

4. The drying tray for vacuum drying of tablet formulations according to claim 1, characterized in that: The protrusions (11) are arranged in a matrix, and ventilation holes (12) are provided between adjacent protrusions (11) in the horizontal and vertical directions.

5. The drying tray for vacuum drying of tablet formulations according to claim 1, characterized in that: The protrusions (11) are arranged in a plum blossom pattern, and the vent holes (12) are arranged in a matrix. Ventilation holes (12) are provided between adjacent protrusions (11) in odd or even rows.

6. The drying tray for vacuum drying of tablet formulations according to claim 1, characterized in that: The protrusions (11) are arranged in a plum blossom pattern, and the ventilation holes (12) are arranged in a plum blossom pattern. Ventilation holes (12) are provided at the center of four adjacent protrusions (11).

7. The drying tray for vacuum drying of tablet formulations according to claim 1, characterized in that: The diameter of the protrusion (11) is 2~4mm, the radius of the top of the protrusion (11) is 1~2mm, the height of the protrusion (11) is 1~4mm, and the distance between adjacent protrusions (11) is 4~6mm; the diameter of the vent hole (12) is 1~2mm.

8. The drying tray for vacuum drying of tablet formulations according to claim 7, characterized in that: The diameter of the protrusion (11) is 2 mm, the radius of the top of the protrusion (11) is 1 mm, the height of the protrusion (11) is 2 mm, and the diameter of the vent (12) is 1 mm.

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