A container level detection apparatus and pipetting accuracy measurement system

Abstract

The utility model belongs to detection device technical field relates to a kind of container liquid level detection equipment and pipetting accuracy measurement system.Container liquid level detection equipment includes ultrasonic detection module, container tray and mobile drive mechanism, and ultrasonic detection module includes at least one row of ultrasonic detector arranged along the first direction, and ultrasonic detector can emit ultrasonic signal and receive reflected signal;Container tray is arranged below ultrasonic detection module, for carrying the container to be detected;Mobile drive mechanism is driven connection with ultrasonic detection module and / or container tray, for driving ultrasonic detection module and container tray relatively move in the second direction;First direction and the second direction are mutually orthogonal.Pipetting accuracy measurement system includes mesa, pipetting device and container liquid level detection equipment.The utility model not only can detect the liquid level in container alone, but also can realize pipetting and detection synchronization, realizes the online quality control to pipetting process.

Description

Technical Field

[0001] This utility model relates to a container liquid level detection device and a liquid transfer accuracy measurement system, belonging to the technical field of detection devices. Background Technology

[0002] In fields such as chemistry, biology, pharmacy, and clinical diagnostics, accurately determining the liquid level of liquid samples in various containers is a fundamental and crucial step. Taking the common microplate as an example, microplates, also often called porous sample trays, typically contain arrays of 48, 96, 384, or even 1536 wells to simultaneously hold a large number of trace liquid samples.

[0003] In various experiments using microplates, a fundamental and crucial step is to confirm that liquid sample has been successfully added to each well and to determine if the liquid level meets the experimental requirements. This is because in some assays, different liquid levels indicate different volumes, which can lead to variations in reagent concentration or reaction conditions, affecting the accuracy of the assay.

[0004] However, the current industry standard for determining the liquid level in each well of a microplate generally relies on high-precision weighing modules. This method indirectly infers the liquid level by measuring changes in liquid weight, and primarily involves two operating modes: one is a single-channel detection mode, where the weighing device must first be zeroed, and then the solution in a single transfer channel is transferred to a dedicated container placed on the weighing module for weighing. The weight value is used to determine if there is an error in the dispensing. After the detection is complete, the liquid must be removed, and the weighing module must be zeroed again before the next channel can be detected. The other mode involves weighing the entire microplate after dispensing, and estimating the average volume or liquid level of the entire plate by comparing it with the theoretical total weight.

[0005] However, this weighing detection method has many problems: First, the purchase and maintenance costs of high-precision weighing modules are high. These modules require regular calibration and cleaning and are susceptible to environmental factors (such as vibration and temperature), affecting stability and increasing experimental costs. Second, the detection efficiency is low, especially in single-channel detection mode, where it is time-consuming and cannot meet the rapid demands of high-throughput experiments. Third, the existing weighing method is not a real-time monitoring tool integrated into the experimental process, but rather a separate, post-experiment detection step. It requires dedicated detection time and consumes special liquid samples (which are usually discarded in single-channel mode). This not only disrupts continuous experimental operations but also wastes valuable samples or reagents. Furthermore, the average value measurement mode cannot accurately reflect the liquid level in individual wells, potentially masking abnormal liquid levels in some wells, thus reducing the accuracy and reliability of the detection.

[0006] Therefore, there is a need in this field for a liquid level detection scheme that can overcome the above-mentioned defects, so as to achieve rapid, accurate, non-contact, and integrated real-time judgment of the liquid level in each hole of the experimental container, thereby improving the reliability of experimental data and the overall efficiency of the experimental process. Utility Model Content

[0007] The purpose of this utility model is to provide a new technical solution to improve or solve the technical problems existing in the prior art as described above.

[0008] The technical solution provided by this utility model is as follows: A container liquid level detection device includes an ultrasonic detection module, a container tray, and a moving drive mechanism. The ultrasonic detection module includes at least one row of ultrasonic detectors arranged along a first direction. The ultrasonic detectors are capable of emitting ultrasonic signals and receiving reflected signals. The container tray is disposed below the ultrasonic detection module and is used to support the container to be tested. The moving drive mechanism is drivenly connected to the ultrasonic detection module and / or the container tray, and is used to drive the ultrasonic detection module and the container tray to move relative to each other in a second direction. The first direction and the second direction are orthogonal to each other.

[0009] Compared with the prior art, the technical solution provided by this utility model has the following beneficial effects: by setting the ultrasonic detection module to include at least one row of ultrasonic detectors, and matching the number of ultrasonic detectors in each row with the number of holes in the container to be tested in the first direction, when the container to be tested on the container tray moves intermittently relative to the ultrasonic detection module in the second direction, the ultrasonic detection module can simultaneously complete the liquid level detection of the entire row of holes at each stopping position. This utility model can realize whole row detection and row-by-row progressive detection, effectively improving the detection efficiency.

[0010] Based on the above technical solution, the present invention can be further improved as follows.

[0011] Furthermore, the container pallet is mounted via a first linear guide pair, and the moving drive mechanism is driven to move the container pallet along the second direction.

[0012] Furthermore, the ultrasonic detection module can adjust its height along a third direction, which is perpendicular to the plane formed by the first direction and the second direction.

[0013] The beneficial effect of adopting the above-mentioned further solution is that it enables the equipment to adapt to containers of different heights and specifications, such as microplates or other sample tubes of different depths, thereby improving the versatility of the equipment.

[0014] Furthermore, it also includes a clamping assembly comprising a clamping strip, a spring, and a blocking portion. The clamping strip is located at one end of the container tray and is slidably disposed relative to the container tray via a second linear guide pair. The spring provides a preload force to the clamping strip, which has a clamping tendency due to the elastic preload force of the spring. The blocking portion is disposed on the movement path of the container tray and can force the clamping strip to move relative to the container tray by contacting the clamping strip or a component connected thereto, thereby achieving opening.

[0015] The beneficial effect of adopting the above-mentioned further solution is that when the container to be tested is automatically placed on the tray by a robotic arm, the tray needs a certain tolerance margin. However, this tolerance margin can lead to inaccurate placement. Therefore, a clamping component is needed to achieve automatic positioning and clamping of the container to be tested. This clamping component ensures that the container to be tested remains in a fixed position during the moving and testing process, preventing displacement or slippage, thereby guaranteeing the accuracy of the test results. Furthermore, the automatic opening and closing mechanism is linked to the movement of the container tray, allowing for the fixing and release of the container to be tested without manual intervention.

[0016] Furthermore, the end of the container tray is provided with a U-shaped groove, which is used to provide clearance and guidance for the movement of the clamping strip.

[0017] Furthermore, the moving drive mechanism is a synchronous belt linear module, which includes a drive motor, a drive wheel, a driven wheel, a synchronous belt, and a connecting pressure plate. The output shaft of the drive motor is connected to the drive wheel, the synchronous belt is wound around the drive wheel and the driven wheel, and the connecting pressure plate is fixedly installed on the synchronous belt and connected to the container tray.

[0018] The beneficial effect of adopting the above-mentioned further solution is that the synchronous belt linear module can drive the container pallet to move smoothly and accurately.

[0019] Furthermore, it also includes an initial position detection component, which is used to initialize the positioning of the container tray. The initial position detection component includes a sensor and a sensing element that cooperates with the sensor. The sensing element is disposed on the container tray, and the sensor is disposed on the equipment frame.

[0020] The beneficial effect of adopting the above-mentioned further solution is that by initializing the positioning of the container pallet, an accurate starting reference is established for the movement stroke of the synchronous belt linear module, thereby ensuring the positional accuracy of all subsequent movements and operations.

[0021] Furthermore, it also includes a travel limiter for limiting the travel distance of the container tray.

[0022] The advantage of adopting the above-mentioned further solution is that by setting a travel limit part, it is possible to prevent the container pallet from exceeding the predetermined range during movement.

[0023] Furthermore, it also includes a controller, which is signal-connected to the ultrasonic detection module. The controller is able to determine whether there is liquid in the container under test and / or the liquid level height and / or calculate the volume of the liquid based on the reflected signal.

[0024] Furthermore, the ultrasonic testing module includes two rows of ultrasonic detectors arranged along a first direction, with the two rows of ultrasonic detectors staggered.

[0025] The beneficial effect of adopting the above-mentioned further solution is that by increasing the center distance between adjacent detectors through the double-row staggered layout, the mutual interference problem under the dense arrangement of multiple ultrasonic sensors is solved, and the accuracy of the data of each detection channel is ensured.

[0026] This utility model also provides a pipetting accuracy measurement system, including a table, a pipetting device, and a container loading and unloading channel. The container loading and unloading channel is located on the table, and the pipetting device is disposed above the table. The pipetting device includes a plurality of pipetting channels that can move in a second direction. It also includes the aforementioned container liquid level detection device, which is disposed on the table. The container liquid level detection device can detect the accuracy of dispensing or aspiration of the pipetting channels, or the container liquid level detection device can detect the liquid level in the container individually.

[0027] Compared with the prior art, the technical solution provided by this utility model has the following beneficial effects: The container liquid level detection device is integrated into the pipetting system. The container liquid level detection device can be configured to perform at least one of the following detection modes: In a first mode, the dispensing accuracy of the corresponding pipetting channel is measured independently by detecting the liquid level of the liquid dispensed into the container by the pipetting channel; in a second mode, the aspiration accuracy of the corresponding pipetting channel is measured by detecting the liquid level in the container after the liquid is aspirated from the container by the pipetting channel; in a third mode, the liquid level in the container is detected independently. Therefore, the pipetting accuracy measurement system of this utility model can not only achieve independent detection of the container liquid level, but also directly and efficiently complete the online measurement of the pipetting accuracy of the pipetting channel, realizing in-situ, online quality control of the pipetting process, solving the problem that traditional methods require interruption of the process and separate sampling and weighing, and achieving seamless integration of detection and experimental processes. Attached Figure Description

[0028] To more clearly illustrate the technical solutions in the embodiments of this utility model or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on the provided drawings without creative effort.

[0029] Figure 1 This is a three-dimensional structural diagram of the container liquid level detection device according to Embodiment 1 of this utility model; Figure 2 For the present utility model Figure 1 A magnified structural diagram of part A; Figure 3 A three-dimensional structural diagram showing the placement of a microplate on the container tray of the equipment; Figure 4 For the present utility model Figure 3 Side view; Figure 5 This is a schematic diagram of the structure of the clamping strip for clamping the micro-perforated plate of this utility model; Figure 6 This is a schematic diagram of the clamping strip installation structure of this utility model; Figure 7 This is a three-dimensional structural diagram of the internal structure of the container liquid level detection device of this utility model from another perspective; Figure 8 This is a three-dimensional structural diagram of the container liquid level detection device according to Embodiment 2 of this utility model; Figure 9 This is a schematic diagram of the internal structure of the container liquid level detection device according to Embodiment 2 of this utility model; Figure 10 This is a structural schematic diagram of Embodiment 3 of the present invention; Figure 11 This is a structural schematic diagram of Embodiment 4 of the present invention; Figure 12 For the present utility model Figure 11 A magnified structural diagram of part B.

[0030] In the diagram, 1. Ultrasonic detector; 2. Container tray; 3. First linear guide pair; 4. Clamping strip; 5. Spring; 6. Blocking part; 7. U-shaped groove; 8. Slider; 9. Second linear guide pair; 10. Drive motor; 11. Driving wheel; 12. Driven wheel; 13. Synchronous belt; 14. Connecting pressure plate; 15. Sensor; 16. Sensing element; 17. Stroke limit part; 18. Controller; 19. Top plate; 20. Bottom plate; 21. Microporous plate; 22. Elongated hole; 23. Platform; 24. Pipette channel. Detailed Implementation

[0031] The serial numbers assigned to components in this document, such as "first" and "second," are used only to distinguish the objects described and do not imply any priority in order or any specific technical meaning. Furthermore, the concepts of "connection" and "linkage" mentioned in this application, unless otherwise specified, are considered to include both direct connection (linkage) and indirect connection (linkage).

[0032] When interpreting the description of this application, it should be clarified that terms such as "upper," "lower," "front," "back," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," "clockwise," and "counterclockwise," indicating directions or positional relationships, are based on the perspective and layout shown in the accompanying drawings. They are intended to facilitate explanation and simplify the description process, and are not absolute limitations on the actual location, construction method, or operating mode of the described device or element. Therefore, these terms should not be construed as restrictive interpretations of the content of this application.

[0033] The principles and features of this utility model are described below with reference to examples. The examples are only used to explain this utility model and are not intended to limit the scope of this utility model.

[0034] Example 1: like Figure 1 - Figure 7 As shown, a container liquid level detection device includes an ultrasonic detection module, a container tray 2, and a moving drive mechanism. The ultrasonic detection module includes at least one row of ultrasonic detectors 1 arranged along a first direction. The ultrasonic detectors 1 are capable of emitting ultrasonic signals and receiving reflected signals. The container tray 2 is disposed below the ultrasonic detection module and is used to support the container to be tested. The moving drive mechanism is drivenly connected to the ultrasonic detection module and / or the container tray 2, and is used to drive the ultrasonic detection module and the container tray 2 to move relative to each other in a second direction. The first direction and the second direction are orthogonal to each other.

[0035] It should be noted that, in this embodiment, the first direction, the second direction, and the third direction can be referred to the appendix of the specification. Figure 1 The first direction is consistent with the instruction manual. Figure 1 The X-axis direction is consistent with the first X-axis direction, and the second direction is consistent with the one in the instruction manual. Figure 1 The Y-axis direction is consistent with the Y-axis direction, and the third direction is consistent with the instruction manual. Figure 1 The Z-axis direction is consistent. In this embodiment, the container to be tested is a microporous plate 21. By setting the ultrasonic detection module to at least one row of ultrasonic detectors 1, and adapting the number of detectors in each row to the number of holes in the microporous plate 21 in the first direction, synchronous detection of the entire row can be achieved. For example, for a 96-hole microporous plate 21 with 8 rows and 12 columns, 8 ultrasonic detectors 1 can be set in the first direction. During operation, the microporous plate 21 located on the container support platform moves intermittently relative to the ultrasonic detection module along the second direction; at each stopping position, the row of ultrasonic detectors 1 can simultaneously complete the liquid level detection of the entire row of holes.

[0036] In this embodiment, the container tray 2 is mounted via a first linear guide rail pair 3, and the moving drive mechanism is driven to connect with the container tray 2 to drive the container tray 2 to move along the second direction.

[0037] Of course, in another embodiment, the moving drive mechanism can also be connected to the ultrasonic detection module to drive the ultrasonic detection module to move along the second direction.

[0038] More specifically, in this embodiment, the ultrasonic detection module, the container tray 2, and the moving drive mechanism are all installed inside the equipment housing. The equipment housing includes a bottom plate 20 and a top plate 19. The ultrasonic detection module is connected below the top plate 19. The first linear guide rail pair 3 is installed on the bottom plate 20. The moving drive mechanism can drive the container tray 2 to move along the first linear guide rail pair 3.

[0039] The device also includes a clamping assembly comprising a clamping strip 4, a spring 5, and a blocking part 6. The clamping strip 4 is located at one end of the container tray 2. A second linear guide 9 is provided at the bottom of the container tray 2. The clamping strip 4 is slidably disposed relative to the container tray 2 via the second linear guide 9. One end of the spring 5 is connected to the clamping strip 4 or a component connected thereto (e.g., a slide block / slider 8), and the other end of the spring 5 is fixedly connected to the container tray 2. The spring 5 provides a preload force to the clamping strip 4, and the clamping strip 4 has a clamping tendency due to the elastic preload force of the spring 5. The blocking part 6 is disposed on the inner side wall of the device housing and is located on the movement path of the container tray 2. The blocking part 6 can contact the clamping strip 4 or a component connected thereto, forcing the clamping strip 4 to overcome the elastic preload force of the spring 5 and move relative to the container tray 2, thereby opening the clamping strip 4. The clamping assembly enables automatic positioning and clamping of the container to be tested, ensuring that the container remains in a fixed position during the moving test process and will not shift or slip, thus guaranteeing the accuracy of the test results. Furthermore, the automatic opening and closing mechanism is linked to the movement of the container tray 2, allowing for the fixing and release of the container to be tested without manual intervention.

[0040] The container tray 2 is provided with a U-shaped groove 7 at its end, which is used to provide clearance and guidance for the movement of the clamping strip 4.

[0041] The moving drive mechanism is a synchronous belt linear module, which includes a drive motor 10, a drive wheel 11, a driven wheel 12, a synchronous belt 13, and a connecting pressure plate 14. The output shaft of the drive motor 10 is connected to the drive wheel 11. The synchronous belt 13 is wound around the drive wheel 11 and the driven wheel 12. The connecting pressure plate 14 is fixedly installed on the synchronous belt 13 and is connected to the container tray 2.

[0042] The device also includes an initial position detection component for initializing the positioning of the container tray 2. The initial position detection component includes a sensor 15 and a sensing element 16 that cooperates with the sensor 15. The sensing element 16 is disposed on the container tray 2, and the sensor 15 is disposed on the device frame.

[0043] The device also includes a travel limiter 17, which limits the travel distance of the container pallet 2. By providing the travel limiter 17, it is possible to prevent the container pallet 2 from exceeding a predetermined range during movement.

[0044] The device also includes a controller 18, which is signal-connected to the ultrasonic detection module. The controller 18 is able to determine whether there is liquid in the container under test and / or the liquid level height based on the reflected signal.

[0045] The working method of the container liquid level detection device of this utility model is as follows: When the equipment starts, the drive motor 10 of the synchronous belt linear module drives the container tray 2 to move to the preset loading position. At this position, the clamping strip 4 is in the open state under the action of the blocking part 6 (see reference). Figure 3 Operators or automated equipment place the microplate 21 to be tested in the designated area of ​​the container carrying platform.

[0046] Subsequently, the drive motor 10 drives the container tray 2 to move closer to the ultrasonic detection module. Then, the slider 8 connected to the clamping strip 4 separates from the blocking part 6. Under the elastic force of the spring 5, the clamping strip 4 automatically clamps one end of the microporous plate 21 (see reference). Figure 5 This completes the automatic fixing of the container to be tested.

[0047] The drive motor 10 drives the container tray 2 and the microporous plate 21 clamped on it to move intermittently along the second direction. Each time the microporous plate 21 moves one row spacing and stops at the target position, a row of ultrasonic detectors 1 arranged along the first direction in the ultrasonic detection module operates, emitting ultrasonic signals to the corresponding row of holes and receiving reflected signals. The liquid level reflection signals of all holes in this row are collected and transmitted to the controller 18. The controller 18 receives and processes the reflection signals of each row of holes, and through a preset algorithm, such as measuring the emission and reception time of the sound pulse, compares the reflected signals with a threshold to determine whether liquid exists in each hole and / or calculates the liquid level height information, thereby determining the liquid volume. The controller 18 records and stores the liquid level status information of all holes in the entire microporous plate 21, and can generate a detection report or transmit data to a host computer.

[0048] After all tests are completed, the container platform returns to the loading position.

[0049] When the slider 8 contacts the blocking part 6 again, the clamping strip 4 is forced to open, and the operator or automation module can then remove the microplate 21 that has completed the test.

[0050] Example 2: Unlike Embodiment 1, in this embodiment, as follows: Figure 8 and Figure 9As shown, the ultrasonic detection module can adjust its height along a third direction, which is perpendicular to the plane formed by the first direction and the second direction.

[0051] The device housing has elongated holes 22 on both sides. The ultrasonic detection module can be fixed at any height position of the elongated holes 22, so that the device can adapt to containers of different heights and specifications, such as microplates 21 of different depths or other sample tubes, thus enhancing the versatility of the device.

[0052] Example 3: Unlike Example 1, such as Figure 10 As shown, in this embodiment, the ultrasonic detection module includes two rows of ultrasonic detectors 1 arranged along a first direction, with the two rows of ultrasonic detectors 1 staggered. Through the intermittent movement of the container tray 2, the two rows of detectors detect different rows of holes directly below them at each stopping position, completing a scan of the entire microporous plate 21. To effectively avoid signal interference between adjacent sensors, the first row of detectors 1 and the second row of detectors 1 can be activated alternately.

[0053] Compared to a single-row parallel layout, a double-row staggered layout increases the center distance between adjacent detectors. The controller 18 can control the two rows of ultrasonic detectors 1 to emit pulses simultaneously, solving the problem of mutual interference under dense arrangement of multiple ultrasonic sensors and ensuring the accuracy of data from each detection channel.

[0054] Example 4: like Figure 11 As shown, this embodiment discloses a pipetting accuracy measurement system, including a platform 23, a pipetting device, and a container loading / unloading channel. The container loading / unloading channel is located on the platform 23, and the pipetting device is disposed above the platform 23. The pipetting device includes a plurality of pipetting channels 24 that can move in a second direction, and also includes the container liquid level detection device, which is disposed on the platform 23. The container can be transported to the container tray 2 of the container liquid level detection device through the pipetting channels (when it is necessary to load or unload the container, the pipetting channel can pick up the gripper to realize the gripping of the container). The container liquid level detection device can detect the accuracy of liquid aspiration or dispensing of the pipetting channels 24, or the container liquid level detection device can detect the liquid level in the container alone.

[0055] The container level detection device is integrated into a pipetting system, and the container level detection device can be configured to perform at least one of the following detection modes: In the first mode, dispensing and detection are performed simultaneously. Specifically, an empty container or one in a known initial state is placed on the tray 2 of the container level detection device. The clamping assembly automatically and reliably fixes the container in a predetermined position during the movement of the container tray 2. The pipetting device dispenses liquid into the container according to instructions. Subsequently, the container tray 2 moves intermittently along a second direction, and the ultrasonic detector 1 simultaneously detects the liquid level height in the container. The controller 18 calculates the actual dispensing volume of each pipetting channel 24 based on the liquid level data and compares it with the target volume. Thus, after the liquid addition is completed, the detection process can begin, enabling individual measurement and calibration of the dispensing accuracy of each pipetting channel 24, as well as real-time quality control of the dispensing process.

[0056] When the container tray 2 moves toward the ultrasonic module, the container itself (microplate 21) remains relatively fixed on the tray 2 due to the clamping components; and its position remains relatively fixed when it is removed from the ultrasonic module. Therefore, precise sample addition is possible for the processing of the pipetting channel 24.

[0057] In the second mode, the aspiration accuracy of the corresponding pipetting channel is measured by detecting the liquid level in the container after the liquid is aspirated from the container by the pipetting channel.

[0058] In the third mode, the system can also operate the container level detection function independently. The container is transported to the tray 2 of the container level detection device, and the container tray 2 moves intermittently along the second direction. The ultrasonic detector 1 simultaneously detects the liquid level height in each container. This process does not involve liquid transfer operations, but only measures and judges the existing liquid level in the container.

[0059] Therefore, the pipetting accuracy measurement system of this invention can not only independently detect the liquid level in the container, but also directly and efficiently complete the online measurement of the accuracy of dispensing or aspiration in the pipetting channel, realizing online quality control of the pipetting process, solving the problem that traditional methods require interruption of the process and separate sampling and weighing, and achieving seamless integration of detection and experimental processes.

[0060] The above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. A container liquid level detection device, characterized in that, The device includes an ultrasonic testing module, a container tray (2), and a moving drive mechanism. The ultrasonic testing module includes at least one row of ultrasonic detectors (1) arranged along a first direction. The container tray (2) is located below the ultrasonic testing module and is used to carry the container to be tested. The moving drive mechanism is driven to the ultrasonic testing module and / or the container tray (2) and is used to drive the ultrasonic testing module and the container tray (2) to move relative to each other in a second direction. The first direction and the second direction are orthogonal to each other.

2. The container liquid level detection device according to claim 1, characterized in that, The container tray (2) is mounted via a first linear guide rail pair (3), and the moving drive mechanism is driven to connect with the container tray (2).

3. The container liquid level detection device according to claim 1, characterized in that, The ultrasonic detection module can be height adjusted along a third direction, which is perpendicular to the plane formed by the first direction and the second direction.

4. The container liquid level detection device according to claim 1, characterized in that, It also includes a clamping assembly comprising a clamping bar (4), a spring (5), and a blocking part (6). The clamping bar (4) is located at one end of the container tray (2) and is slidably disposed relative to the container tray (2) via a second linear guide pair (9). The spring (5) is used to provide an elastic preload for the clamping bar (4). The blocking part (6) is disposed on the movement path of the container tray (2) and is capable of contacting the clamping bar (4) or a component connected thereto, thereby forcing the clamping bar (4) to move relative to the container tray (2) against the elastic preload of the spring (5).

5. The container liquid level detection device according to claim 4, characterized in that, The container tray (2) is provided with a U-shaped groove (7) at its end, which is used to provide clearance and guidance for the movement of the clamping strip (4).

6. The container liquid level detection device according to any one of claims 1-5, characterized in that, The moving drive mechanism is a synchronous belt linear module, which includes a drive motor (10), a drive wheel (11), a driven wheel (12), a synchronous belt (13), and a connecting pressure plate (14). The output shaft of the drive motor (10) is connected to the drive wheel (11). The synchronous belt (13) is wound around the drive wheel (11) and the driven wheel (12). The connecting pressure plate (14) is fixedly installed on the synchronous belt (13) and is connected to the container tray (2).

7. The container liquid level detection device according to claim 6, characterized in that, It also includes an initial position detection component, which is used to initialize the positioning of the container tray (2). The initial position detection component includes a sensor (15) and a sensing element (16) that cooperates with the sensor (15). The sensing element (16) is disposed on the container tray (2), and the sensor (15) is disposed on the equipment frame.

8. The container liquid level detection device according to claim 1, characterized in that, It also includes a travel limiter (17) for limiting the travel of the container tray (2).

9. The container liquid level detection device according to claim 1, characterized in that, It also includes a controller (18), which is signal-connected to the ultrasonic detection module. The controller (18) can determine whether there is liquid in the container under test and / or the liquid level height and / or calculate the volume of the liquid based on the reflected signal.

10. The container liquid level detection device according to claim 1, characterized in that, The ultrasonic testing module includes two rows of ultrasonic detectors (1) arranged along a first direction, with the two rows of ultrasonic detectors (1) staggered.

11. A pipetting accuracy measurement system, comprising a platform (23), a pipetting device, and a container loading / unloading channel, wherein the container loading / unloading channel is located on the platform (23), the pipetting device is disposed above the platform (23), and the pipetting device includes a plurality of pipetting channels (24) movable in a second direction, characterized in that, It also includes a container liquid level detection device as described in any one of claims 1-10, wherein the container liquid level detection device is disposed on the table (23), and the container liquid level detection device is capable of detecting the accuracy of liquid dispensing or aspiration of the liquid transfer channel (24), or the container liquid level detection device is capable of detecting the liquid level in the container separately.

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