An on-line quality control sampling device

CN224788350UActive Publication Date: 2026-09-22TIANJIN FALMA PHARMACEUTICAL CO LTD
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Patent Information

Application Number
CN202522261088.9
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-10-27
Publication Date
2026-09-22
Estimated Expiration
2035-10-27

AI Technical Summary

Benefits of technology

通过采样组件的设置,能够通过各零部件的互相配合,提高采样的效率及便利性,通过可调的采样间距,可以满足批量采样检测的要求,通过电动推杆、调节架、多个调节辊及抵接板,可以通过电动推杆的运行,带动多个调节辊进行位置调整,以便快速使其端部的多个采样管与样品对应,进而配合着抽吸机、检测仪及仪表,则可以快速对检测结果进行记录,进一步提高寡核苷酸生产中在线质量控制的效率。

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Abstract

The utility model discloses a production on -line quality control sampling device belongs to oligonucleotide production field, including work table and sampling component, and sampling component includes the detection frame of installing on the top end of work table, and the outer wall of detection frame is equipped with electric push rod, and the output of electric push rod is equipped with detection table, and the lower bottom of detection table is fixedly connected with the adjusting frame, and the inner wall of adjusting frame is slidably connected with the adjusting roller, through the cooperation of each device, improves the efficiency and the convenience of sampling, through adjustable sampling spacing, can satisfy the requirement of batch sampling detection, through electric push rod, adjusting frame, multiple adjusting rollers and the abutting plate, can through the operation of electric push rod, drives multiple adjusting rollers and carries out position adjustment to the end of multiple sampling tubes and sample correspond with fast, and then cooperate with the suction machine, detector and instrument, then can record the detection result fast, further improves the efficiency of oligonucleotide production on -line quality control.
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Description

Technical Field

[0001] This utility model relates to the field of oligonucleotide production technology, specifically to an online quality control sampling device for production. Background Technology

[0002] Oligonucleotides are a class of short-chain nucleic acid molecules formed by a small number of nucleotides linked by phosphodiester bonds. They are key molecular tools in the fields of life sciences, medicine, and biotechnology. Their core characteristics are short chains, customizability, and well-defined functions. During their production process, the production of oligonucleotides can be sampled and tested in real time by setting up sampling devices, thereby improving the overall production quality.

[0003] An investigation revealed that a utility model patent (publication number: CN221173966U) discloses a sampling device for testing plastic powder. The device includes an electric heating box containing a test tube rack with several test tubes. A needle tube is attached to the upper side of each test tube, and an externally threaded sleeve is attached to the upper end of the needle tube. A sliding sleeve is attached to the upper end of the externally threaded sleeve, and a rubber stopper is located inside the sliding sleeve. This utility model incorporates a vibration component. When powder cannot be discharged from the needle tube by moving through the rubber stopper, pulling a pull plate causes a sliding plate at one end of a sliding rod to slide within a fixed cylinder, compressing a spring. Releasing the pull plate then causes the spring to extend, pushing a rubber protrusion at one end of the sliding plate to impact the sliding sleeve, causing it to vibrate. The vibration is transmitted to the needle tube through the externally threaded sleeve, thus discharging the powder from the needle tube. The vibration component facilitates the discharge of powder from the needle tube, improving the device's practicality.

[0004] Although the aforementioned patent improves the stability and efficiency of material testing by setting up components such as test tube racks, needle tubes, and vibration components, and reduces the accumulation of materials in test tubes during testing, the production process is often carried out in batches to improve the completeness of the test data. However, this component still requires manual adjustment of the testing position, which not only increases the intensity of operation but also reduces the efficiency of testing.

[0005] Therefore, this utility model provides an online quality control sampling device for production to solve the above problems. Utility Model Content

[0006] This invention provides an online quality control sampling device for production, which aims to solve the problems mentioned in the background art.

[0007] To achieve the above objectives, this utility model provides the following technical solution: An online quality control sampling device for production includes a workbench and a sampling component, wherein the sampling component includes a detection frame mounted on the top of the workbench; An electric push rod is installed on the outer wall of the testing frame. A testing platform is installed at the output end of the electric push rod. An adjusting frame is fixedly connected to the bottom end of the testing platform. An adjusting roller is slidably connected to the inner wall of the adjusting frame. The outer walls of the ends of multiple adjusting rollers are fixedly connected by compression springs. A screw is rotatably connected to the top end of the testing platform. An abutment plate is rotatably sleeved at the end of the screw. The bottom end of the abutment plate abuts against the top ends of multiple adjusting rollers. A clamping assembly is provided at the end of the adjusting roller away from the compression spring.

[0008] As a preferred technical solution of this application, the clamping assembly includes a universal seat fixedly connected to the end of the adjusting roller, and a clamping block is slidably connected to the inner wall of the universal seat. The inner walls of the two clamping blocks are fixedly connected by a connecting spring.

[0009] As a preferred technical solution of this application, the clamping assembly further includes a clamping arc plate fixedly connected to the end of the clamping block, and a sampling tube is clamped between the inner walls of the two clamping arc plates, and a suction hose is fixedly connected to the upper top end of the sampling tube.

[0010] As a preferred technical solution of this application, a suction machine is fixedly connected to the top of the testing platform, the output end of the suction machine is fixedly connected to the end of the suction hose, a testing instrument is installed on the outer wall of the testing frame, the output end of the suction machine is fixedly connected to the input end of the testing instrument through a discharge pipe, and an instrument is installed on the top of the testing instrument.

[0011] As a preferred technical solution of this application, a rotating seat is fixedly connected to the top of the workbench, and a rotating roller is rotatably connected to the inner wall of the rotating seat. A conveyor belt is drivenly sleeved on the outer wall of the two rotating rollers.

[0012] As a preferred technical solution of this application, the internal sliding connection of the testing table is a limiting rod, and the end of the limiting rod is fixedly sleeved on the top of the adjusting frame.

[0013] As a preferred technical solution of this application, an operating device is fixedly connected to the top of the workbench, and the outer wall of the operating device is coated with a waterproof coating.

[0014] The beneficial effects of this utility model are as follows: By setting up the sampling components, the efficiency and convenience of sampling can be improved through the cooperation of various parts. The adjustable sampling interval can meet the requirements of batch sampling and testing. Through the electric push rod, adjustment frame, multiple adjustment rollers and abutment plate, the operation of the electric push rod can drive multiple adjustment rollers to adjust their positions so that multiple sampling tubes at their ends can be quickly aligned with the sample. In conjunction with the suction machine, detector and instrument, the test results can be quickly recorded, further improving the efficiency of online quality control in oligonucleotide production. Attached Figure Description

[0015] Figure 1 This is a schematic diagram of the overall structure of this utility model; Figure 2 This is a schematic diagram of the material discharge pipe in this utility model; Figure 3 This is a schematic diagram of the compression spring in this utility model; Figure 4 This is a schematic diagram of the universal joint structure in this utility model; Figure 5 for Figure 4 A schematic diagram of the structure at point A in the middle.

[0016] In the picture: 1. Workbench; 2. Testing frame; 3. Electric push rod; 4. Testing table; 5. Adjusting frame; 6. Adjusting roller; 7. Compression spring; 8. Screw; 9. Abutment plate; 10. Universal seat; 11. Clamping block; 12. Connecting spring; 13. Clamping arc plate; 14. Sampling tube; 15. Suction hose; 16. Suction machine; 17. Detector; 18. Discharge pipe; 19. Instrument; 20. Rotary seat; 21. Rotary roller; 22. Conveyor belt; 23. Limiting rod; 24. Operating instrument. Detailed Implementation

[0017] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0018] This utility model provides an online quality control sampling device for production, such as... Figures 1-5 As shown, the online quality control sampling device includes a workbench 1 and a sampling component, the sampling component including a detection frame 2 installed on the top of the workbench 1; An electric push rod 3 is installed on the outer wall of the testing frame 2. A testing platform 4 is installed at the output end of the electric push rod 3. An adjusting frame 5 is fixedly connected to the bottom end of the testing platform 4. An adjusting roller 6 is slidably connected to the inner wall of the adjusting frame 5. The outer walls of the ends of multiple adjusting rollers 6 are fixedly connected by compression springs 7. A screw 8 is rotatably connected to the top end of the testing platform 4. An abutment plate 9 is rotatably sleeved at the end of the screw 8. The bottom end of the abutment plate 9 abuts against the top end of multiple adjusting rollers 6. A clamping assembly is provided at the end of the adjusting roller 6 away from the compression spring 7.

[0019] The clamping assembly includes a universal seat 10 fixedly connected to the end of the adjusting roller 6, and a clamping block 11 slidably connected to the inner wall of the universal seat 10. The inner walls of the two clamping blocks 11 are fixedly connected by a connecting spring 12.

[0020] The clamping assembly also includes clamping arc plates 13 fixedly connected to the end of the clamping block 11. The inner walls of the two clamping arc plates 13 clamp the sampling tube 14, and the upper top end of the sampling tube 14 is fixedly connected to the suction hose 15.

[0021] Specifically, the workbench 1 provides sufficient stability for online sampling of oligonucleotides, ensuring smooth operation during quality testing. The various components of the sampling assembly work together to allow operators to easily adjust the spacing of multiple sampling tubes 14 according to the sampling environment, enabling rapid sampling. Rotating the screw 8 allows it to rotate inside the detection table 4, causing the end plate 9 to continuously abut against multiple adjusting rollers 6, allowing them to slide against the inner wall of the adjusting frame 5. This adjusts the spacing between the multiple sampling tubes 14 according to different sampling targets. The compression spring 7, through its material properties, allows for reset during operation. This system enables multiple adjusting rollers 6 to be reset. The universal seat 10 at the end of the adjusting roller 6 allows for easy angle adjustment of the clamping block 11 and clamping arc plate 13 at its end, thereby adjusting the sampling angle of the sampling tube 14 and further improving the convenience of sampling. The connecting spring 12 allows the two clamping blocks 11 to continuously retract, thereby increasing the clamping force with the sampling tube 14. The suction hose 15 facilitates the suction of oligonucleotide raw materials, thereby improving the sampling efficiency. This component has a simple structure, strong practicality, and can improve the adjustability and flexibility of sampling, thereby improving the efficiency of online quality control.

[0022] A suction machine 16 is fixedly connected to the top of the testing platform 4. The output end of the suction machine 16 is fixedly connected to the end of the suction hose 15. A detector 17 is installed on the outer wall of the testing frame 2. The output end of the suction machine 16 is fixedly connected to the input end of the detector 17 through the discharge pipe 18. An instrument 19 is installed on the top of the detector 17.

[0023] Specifically, the suction machine 16 at the top of the testing station 4 can quickly aspirate oligonucleotides through the suction hose 15 and sampling tube 14, while the discharge pipe 18 can transport the material to the inside of the detector 17 for rapid testing. The instrument 19 at the top of the detector 17 can display the test results, which makes it easier for operators to record data and improve the accuracy of the test results.

[0024] A rotating base 20 is fixedly connected to the top of the workbench 1. A rotating roller 21 is rotatably connected to the inner wall of the rotating base 20. A conveyor belt 22 is driven to the outer wall of the two rotating rollers 21.

[0025] Therefore, the internal sliding connection of the testing table 4 is limited by the limit rod 23, and the end of the limit rod 23 is fixedly sleeved on the top of the adjusting frame 5.

[0026] An operating instrument 24 is fixedly connected to the top of the workbench 1, and the outer wall of the operating instrument 24 is coated with a waterproof coating.

[0027] Specifically, the oligonucleotide material can be transported through the rotary seat 20, rotary roller 21 and conveyor belt 22 at the top of the workbench 1, improving the overall processing efficiency. The sliding limit rod 23 inside the detection table 4 can be used to make the adjustment frame 5 stable for longitudinal adjustment, improving the stability of the adjustment. The operating instrument 24 can be used to facilitate the operator to operate the sampling and make it easy for the operator to control the sampling process in real time.

[0028] The above description is only a preferred embodiment of the present utility model, but the protection scope of the present utility model is not limited thereto. Any equivalent substitutions or changes made by those skilled in the art within the technical scope disclosed in the present utility model, based on the technical solution and the inventive concept of the present utility model, should be included within the protection scope of the present utility model.

Claims

1. A production online quality control sampling device, comprising a workbench (1) and a sampling component, characterized in that: The sampling assembly includes a detection frame (2) mounted on the top of the workbench (1); An electric push rod (3) is installed on the outer wall of the testing frame (2). A testing platform (4) is installed at the output end of the electric push rod (3). An adjustment frame (5) is fixedly connected to the bottom end of the testing platform (4). An adjustment roller (6) is slidably connected to the inner wall of the adjustment frame (5). The outer walls of the ends of multiple adjustment rollers (6) are fixedly connected by compression springs (7). A screw (8) is rotatably connected to the top end of the testing platform (4). An abutment plate (9) is rotatably sleeved at the end of the screw (8). The bottom end of the abutment plate (9) abuts against the top end of multiple adjustment rollers (6). A clamping assembly is provided at the end of the adjustment roller (6) away from the compression spring (7).

2. The production online quality control sampling device according to claim 1, characterized in that: The clamping assembly includes a universal seat (10) fixedly connected to the end of the adjusting roller (6), and a clamping block (11) is slidably connected to the inner wall of the universal seat (10). The inner walls of the two clamping blocks (11) are fixedly connected by a connecting spring (12).

3. The production online quality control sampling device according to claim 2, characterized in that: The clamping assembly also includes a clamping arc plate (13) fixedly connected to the end of the clamping block (11), and the inner walls of the two clamping arc plates (13) clamp a sampling tube (14), and the upper top end of the sampling tube (14) is fixedly connected to a suction hose (15).

4. The production online quality control sampling device according to claim 3, characterized in that: A suction machine (16) is fixedly connected to the top of the testing platform (4). The output end of the suction machine (16) is fixedly connected to the end of the suction hose (15). A detector (17) is installed on the outer wall of the testing frame (2). The output end of the suction machine (16) is fixedly connected to the input end of the detector (17) through the discharge pipe (18). An instrument (19) is installed on the top of the detector (17).

5. The production online quality control sampling device according to claim 1, characterized in that: The top of the workbench (1) is fixedly connected to a turntable (20), and the inner wall of the turntable (20) is rotatably connected to a roller (21). The outer walls of the two rollers (21) are connected to a conveyor belt (22).

6. The production online quality control sampling device according to claim 1, characterized in that: The detection platform (4) has a sliding connection to a limiting rod (23), and the end of the limiting rod (23) is fixedly sleeved on the top of the adjustment frame (5).

7. The production online quality control sampling device according to claim 6, characterized in that: An operating instrument (24) is fixedly connected to the top of the workbench (1), and the outer wall of the operating instrument (24) is coated with a waterproof coating.

Citation Information

Patent Citations

  • Sampling device for plastic powder detection test

    CN221173966U