A mineral medicine detection sample extraction device

Abstract

The utility model provides a kind of mineral medicine detection sample extraction device, comprising: fixed frame and the driving device being set on fixed frame;Grinding mechanism is set on fixed frame, and driving device output shaft passes through the top of grinding mechanism and is placed in the inside of grinding mechanism;Extraction mechanism is set on fixed frame, and is placed below grinding mechanism, and grinding mechanism and extraction mechanism are communicated by connecting cylinder;Detection mechanism is set on fixed frame, and extraction mechanism and detection mechanism are communicated by liquid outlet pipe;First liquid storage bottle and second liquid storage bottle are respectively set on fixed frame;Controller is set on fixed frame, and is connected with grinding mechanism, extraction mechanism, detection mechanism, first liquid storage bottle and second liquid storage bottle respectively;The mineral medicine detection sample extraction device proposed in the utility model can effectively isolate air, ensure that the proportion of arsenic and mercury form in detection result is consistent with actual content, meet the accurate requirement of form detection.

Description

Technical Field

[0001] This utility model relates to the field of extraction equipment technology, and in particular to a sample extraction device for mineral drug detection. Background Technology

[0002] In pediatric formulations containing cinnabar (mainly mercuric sulfide, HgS) and realgar (mainly arsenic disulfide, As2S2), the differences in the speciation of arsenic and mercury significantly affect the safety of medication. Among them, As(III) is about 60 times more toxic than As(V), and methylmercury is far more toxic than inorganic mercury. Accurate determination of the content of different speciations is a key detection indicator stipulated in the Chinese Pharmacopoeia, and air oxidation is the core pain point that leads to the distortion of speciation detection results.

[0003] In existing technologies, the pretreatment for arsenic and mercury speciation detection in such preparations requires multiple steps, and the entire process involves exposure to air, with oxidation issues occurring throughout: First, in the grinding stage, sample crushing takes 5-10 minutes, during which As(III) is easily oxidized to As(V) upon contact with air, resulting in an As(III) oxidation rate of 12%-18% after a single grinding; Second, in the transfer stage, the ground sample needs to be manually scooped into the extraction vessel, with an exposure time of about 2-3 minutes, and air disturbance during the transfer process exacerbates oxidation, further increasing the oxidation rate of some samples by 5%-8%; Third, in the extraction stage, traditional extraction vessels are mostly open or semi-open, and while oxygen solubility decreases during high-temperature acid digestion (180℃), residual oxygen remains. During room-temperature intestinal fluid-simulated extraction (37℃), oxygen is more easily dissolved in the liquid, leading to continuous oxidation of As(III), ultimately resulting in a lower As(III) proportion in the detection results, significantly deviating from the actual content. Utility Model Content

[0004] The purpose of this utility model is to provide a mineral drug detection sample extraction device that can solve the above-mentioned technical problems.

[0005] This utility model provides a sample extraction device for mineral drug detection, comprising:

[0006] A fixed frame and a drive device mounted on the fixed frame;

[0007] The grinding mechanism for grinding and screening samples is mounted on a fixed frame, and the output shaft of the drive device passes through the top of the grinding mechanism and is placed inside the grinding mechanism.

[0008] An extraction mechanism for extracting the ground sample is mounted on a fixed frame and placed below the grinding mechanism, and the grinding mechanism and the extraction mechanism are connected by a connecting cylinder.

[0009] The detection mechanism for detecting the solvent containing the sample after extraction is set on a fixed frame, and the extraction mechanism and the detection mechanism are connected through a liquid outlet pipe.

[0010] The first and second storage bottles, used to respectively input acid and buffer solutions into the extraction mechanism, are respectively mounted on the fixed frame;

[0011] The controller is mounted on a fixed frame and is electrically connected to the drive device, grinding mechanism, extraction mechanism, detection mechanism, first liquid storage bottle and second liquid storage bottle respectively.

[0012] As a further technical solution, the fixing frame is provided with a number of first fixing plates and a number of second fixing plates, and the grinding mechanism and the extraction mechanism are each provided with a number of first connecting plates and a number of second connecting plates; the number of first fixing plates and the number of first connecting plates are fixed by bolts; the number of second fixing plates and the number of second connecting plates are fixed by bolts.

[0013] As a further technical solution, the drive device is mounted on a mounting bracket on a fixed frame; and the output shaft of the drive device includes a first section and a second section; the first section and the second section are connected by a coupling; and the second section passes through a bearing seat mounted on the grinding mechanism and is placed inside the grinding mechanism.

[0014] As a further technical solution, the grinding mechanism includes:

[0015] The grinding chamber consists of an outer grinding chamber and an inner grinding chamber, with the inner grinding chamber located within the outer grinding chamber; and the outlet of the inner grinding chamber corresponds to the outlet of the outer grinding chamber.

[0016] The grinding chamber cover is connected to the outer grinding chamber; and the grinding chamber cover is provided with a feed inlet.

[0017] The grinding head is placed inside the grinding cavity, and the output shaft of the drive device is connected to the grinding head;

[0018] A filter screen is installed inside the grinding chamber.

[0019] As a further technical solution, a positioning ring platform is provided on the inner wall of the grinding outer cavity, and a positioning ring groove is provided in the grinding inner cavity; the positioning ring platform and the positioning ring groove are compatible.

[0020] As a further technical solution, the extraction mechanism includes:

[0021] The extraction chamber consists of an outer extraction chamber and an inner extraction chamber, with the inner extraction chamber located within the outer extraction chamber; and a heating layer is fitted onto the outer surface of the inner extraction chamber.

[0022] An extraction chamber cover is connected to the extraction outer chamber; and a first connection port, a second connection port and a third connection port are provided on the extraction chamber cover; the first connection port is connected to the first liquid storage bottle through a conduit, the second connection port is connected to the second liquid storage bottle through a conduit, and the third connection port is connected to the nitrogen cylinder through a gas pipe.

[0023] Several detection ports are provided on the extraction chamber cover, and several detection tubes are provided in the detection ports.

[0024] As a further technical solution, the extraction mechanism also includes:

[0025] A stirring element is placed inside the extraction chamber;

[0026] The driving body is located inside the extraction outer chamber and is magnetically connected to the stirring body.

[0027] As a further technical solution, an annular support plate is provided on the inner wall of the extraction outer cavity, and an annular pressure plate is provided on the outer surface of the extraction inner cavity, with the annular support plate and the annular pressure plate being compatible.

[0028] As a further technical solution, the heating layer is placed on both sides of the annular support plate and the annular pressure plate, and a heat insulation layer is provided between the heating layer and the inner wall of the extraction cavity.

[0029] As a further technical solution, testing institutions include:

[0030] The outer cavity for testing and the testing frame installed inside the outer cavity for testing;

[0031] The first and second detection tubes are mounted on the detection frame and are respectively connected to the first diversion valve via conduits; the first diversion valve is connected to the liquid outlet tube.

[0032] The second diversion valve is connected to the first detection tube and the second detection tube respectively through the drain pipe; and a first detection body and a second detection body are respectively provided at the connection between the first detection tube and the second detection tube and the drain pipe.

[0033] Several waste liquid collection bottles are set at the bottom of the detection outer cavity and connected to the second diversion valve through several waste liquid pipes.

[0034] The technical solution of this utility model eliminates the exposure links of traditional multi-device transfer through the structural design of grinding, extraction and detection. That is, the grinding mechanism and the extraction mechanism are directly connected through the connecting cylinder. After grinding, the sample does not need to be scooped by hand and can fall directly into the extraction mechanism, avoiding the aggravation of oxidation during the transfer stage. At the same time, the extraction mechanism is a closed design, which, together with the nitrogen protection function linked to the controller, can effectively isolate air and ensure that the proportion of arsenic and mercury in the detection results is consistent with the actual content, thus meeting the accuracy requirements of speciation detection. Attached Figure Description

[0035] To more clearly illustrate the specific embodiments of this utility model or the technical solutions in the prior art, the drawings used in the description of the specific embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of this utility model. For those skilled in the art, other drawings can be obtained from these drawings without creative effort.

[0036] Figure 1 This is a perspective view of a mineral drug detection sample extraction device according to the present invention.

[0037] Figure 2 This is a perspective view of the mineral drug detection sample extraction device of this utility model from another angle;

[0038] Figure 3 This is a schematic diagram of the mineral drug detection sample extraction device of this utility model from one angle;

[0039] Figure 4 for Figure 3 A cross-sectional view along the AA direction;

[0040] Figure 5 for Figure 4 Enlarged structural diagram of section X in the middle;

[0041] Figure 6 This is a schematic diagram of the mineral drug detection sample extraction device of this utility model from another angle;

[0042] Figure 7 for Figure 6 Cross-sectional view along the BB direction;

[0043] Figure 8 This is a magnified three-dimensional view of the extraction structure in this utility model.

[0044] Explanation of reference numerals in the attached figures:

[0045] 100-Fixed frame; 101-First fixed piece; 102-Second fixed piece; 103-Mounting frame; 200-Drive device; 201-First section; 202-Second section; 203-Coupling; 204-Bearing seat; 300-Grinding mechanism; 301-First connecting piece; 302-Grinding outer cavity; 303-Grinding inner cavity; 304-Grinding cavity cover; 305-Feed inlet; 306-Grinding head; 307-Filter screen; 308-Positioning ring platform; 309-Positioning ring groove; 400-Extraction mechanism; 401-Second connecting piece; 402-Extraction outer cavity; 403-Extraction inner cavity; 404-Heating layer; 405-Extraction cavity cover; 451-First connection port; 452-Second connection port; 4 53-Third connection port; 461-Temperature sensor; 462-Level sensor; 463-Pressure sensor; 471-Stirring body; 472-Driver body; 481-Annular support plate; 482-Annular pressure plate; 409-Insulation layer; 500-Detection mechanism; 501-Detection outer cavity; 502-Detection frame; 503-First detection tube; 504-Second detection tube; 505-First diverter valve; 506-Second diverter valve; 507-First detection body; 508-Second detection body; 591-Waste liquid collection bottle; 592-Weighing sensor; 601-First storage bottle; 602-Second storage bottle; 700-Controller; 801-Grinding solenoid valve; 802-Discharge pipe; 803-Connecting cylinder. Detailed Implementation

[0046] The technical solution of this utility model will be clearly and completely described below with reference to the embodiments. Obviously, the described embodiments are only some embodiments of this utility model, not all embodiments. Based on the embodiments of this utility model, all other embodiments obtained by those skilled in the art without creative effort are within the protection scope of this utility model.

[0047] In the description of this utility model, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", etc., indicating the orientation or positional relationship are based on the orientation or positional relationship shown in the accompanying drawings, and are only for the convenience of describing this utility model and simplifying the description, and are not intended to indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model.

[0048] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of indicated technical features. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of the stated features. In the description of this utility model, "a plurality of" means two or more, unless otherwise explicitly specified. Furthermore, the terms "installed," "connected," and "linked" should be interpreted broadly; for example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model based on the specific circumstances.

[0049] like Figure 1-8 As shown, the present invention proposes a sample extraction device for mineral drug detection, comprising:

[0050] The fixture 100 and the drive device 200 mounted on the fixture 100; In this utility model, the fixture 100 is made of stainless steel by welding and a PTFE anti-corrosion coating is provided on the surface, thereby effectively preventing corrosion by reagents such as nitric acid and hydrochloric acid.

[0051] The grinding mechanism 300 is mounted on the fixed frame 100, and the output shaft of the drive device 200 passes through the top of the grinding mechanism 300 and is placed inside the grinding mechanism 300. The grinding mechanism 300 grinds and filters the sample. Specifically, after the sample is introduced into the grinding mechanism 300, the grinding mechanism 300 is activated by the drive device 200 to grind the introduced sample. After being filtered inside the grinding mechanism 300, the ground sample falls into the extraction mechanism 400 under its own gravity.

[0052] An extraction mechanism 400 is mounted on a fixed frame 100 and positioned below a grinding mechanism 300. The grinding mechanism 300 and the extraction mechanism 400 are connected via a connecting cylinder 803. The extraction mechanism 400 extracts the ground sample. A first storage bottle 601 and a second storage bottle 602 are respectively mounted on the fixed frame 100. Acid and buffer solutions are respectively introduced into the extraction mechanism 400 through the first storage bottle 601 and the second storage bottle 602. Specifically, after the ground sample enters the extraction mechanism 400, it is stored within the extraction mechanism 400. Acid and buffer solutions are respectively introduced into the extraction mechanism 400 through the first storage bottle 601 and the second storage bottle 602, and the sample undergoes an extraction reaction within the extraction mechanism 400. After the reaction is completed, the sample containing solvent is transferred to the detection mechanism 500. In this invention, the acid solution is preferably hydrofluoric acid or nitric acid, and the buffer solution is preferably phosphate buffer or simulated intestinal fluid.

[0053] The detection mechanism 500 is mounted on the fixed frame 100, and the extraction mechanism 400 is connected to the detection mechanism 500 through the liquid outlet pipe 802; the detection mechanism 500 detects the solvent containing the sample after extraction; when the solvent containing the sample enters the detection mechanism 500, the sample is detected, and the sample is collected after the detection.

[0054] The controller 700 is mounted on the fixed frame 100 and is electrically connected to the drive device 200, grinding mechanism 300, extraction mechanism 400, detection mechanism 500, first storage bottle 601, and second storage bottle 602. During use, the controller 700 controls the drive device 200, grinding mechanism 300, extraction mechanism 400, detection mechanism 500, first storage bottle 601, and second storage bottle 602. It should be noted that the controller 700 preferably has a PLC control board installed inside the control box, and the PLC control board controls the drive device 200, grinding mechanism 300, extraction mechanism 400, detection mechanism 500, first storage bottle 601, and second storage bottle 602.

[0055] The technical solution of this utility model eliminates the exposure links of traditional multi-device transfer through the structural design of grinding, extraction and detection. That is, the grinding mechanism 300 and the extraction mechanism 400 are directly connected through the connecting cylinder 803. After grinding, the sample does not need to be scooped by hand and can fall directly into the extraction mechanism 400, avoiding the aggravation of oxidation during the transfer stage. At the same time, the extraction mechanism 400 is a sealed design, which, together with the nitrogen protection function linked to the controller 700, can effectively isolate air and ensure that the proportion of arsenic and mercury in the detection results is consistent with the actual content, thus meeting the accuracy requirements of speciation detection.

[0056] like Figure 1As shown, the fixing frame 100 is provided with a plurality of first fixing plates 101 and a plurality of second fixing plates 102, and the grinding mechanism 300 and the extraction mechanism 400 are each provided with a plurality of first connecting plates 301 and a plurality of second connecting plates 401; the plurality of first fixing plates 101 and the plurality of first connecting plates 301 are fixed by bolts; the plurality of second fixing plates 102 and the plurality of second connecting plates 401 are fixed by bolts; during the installation stage, the plurality of first connecting plates 301 and the plurality of second connecting plates 401 are respectively aligned with the plurality of first fixing plates 101 and the plurality of second fixing plates 102 and then secured by bolts. The grinding mechanism 300 and the extraction mechanism 400 are connected and fixed to the fixing frame 100 respectively. It should be noted that in this utility model, there are three first fixing plates 101 and two fixing plates 102, and the included angle between adjacent first fixing plates 101 and second fixing plates 102 is 60°. There are three first connecting plates 301 and two connecting plates 401, which are respectively arranged opposite to the first fixing plates 101 and second fixing plates 102. In this way, the fixing strength can be guaranteed after connection, and the stability of the grinding mechanism 300 and the extraction mechanism 400 can also be increased.

[0057] The drive unit 200 is mounted on the mounting bracket 103 on the fixed frame 100; and the output shaft of the drive unit 200 includes a first section 201 and a second section 202; the first section 201 and the second section 202 are connected by a coupling 203; and the second section 202 passes through the bearing seat 204 provided on the grinding mechanism 300 and is placed inside the grinding mechanism 300; in actual use, the drive unit 200 drives the first section 201 to rotate, and drives the second section 202 to rotate in the bearing seat 204 through the coupling 203, thereby driving the grinding mechanism 300; wherein, the drive unit 200 is preferably a variable frequency motor, and the speed can be adjusted as needed; the coupling 203 is preferably a flexible coupling, so that it can compensate for the small coaxiality deviation between the first section 201 and the second section 202 during use, and avoid vibration of the grinding mechanism 300 during use; a deep groove ball bearing is provided inside the bearing seat 204 to ensure the stability of the second section 202 during rotation.

[0058] like Figure 4-7As shown, the grinding mechanism 300 includes an outer grinding cavity 302 and an inner grinding cavity 303, with the inner grinding cavity 303 disposed within the outer grinding cavity 302. The outlet of the inner grinding cavity 303 corresponds to the outlet of the outer grinding cavity 302. A grinding cavity cover 304 is connected to the outer grinding cavity 302, and a feed inlet 305 is provided on the cover 304. A grinding head 306 is placed within the inner grinding cavity 303, and the output shaft of the drive device 200 is connected to the grinding head 306. In this invention, the grinding head 306 forms a conical surface structure, and the roughness of the conical surface is not greater than 0.2 mm. A filter screen 307 is disposed within the inner grinding cavity 303. Specifically, both the inner grinding cavity 303 and the grinding head 306 are made of agate, and a threaded hole is formed on the grinding head 306, through which it is threadedly connected to the second section 202. Figure 4 As shown, the grinding outer cavity 302 is provided with an annular groove. After the grinding cavity cover 304 is placed in the annular groove, it contacts the top of the grinding inner cavity 303 and presses the grinding inner cavity 303. The grinding cavity cover 304 is fixed to the grinding outer cavity 302 by bolts. The grinding cavity cover 304 has an opening for the second section 202 to pass through and connect to the grinding head 306. In addition, the bottom of the grinding inner cavity 303 is a conical structure, and the roughness of the conical surface is no greater than 0.8μm, thereby ensuring that the sample can smoothly enter the discharge port after screening. The filter screen 307 is set above the conical structure. The position of the filter screen 307 is restricted by the conical mechanism to prevent the filter screen 307 from moving excessively.

[0059] In actual use, the sample is introduced into the grinding chamber 303 through the feed port 305. The controller 700 controls the drive device 200 to operate and drive the grinding head 306 to rotate. The rotation speed of the grinding head 306 is 500-5000 r / min. The sample is ground by the shearing and extrusion forces generated by the grinding head 306. After grinding, the sample passes through the filter screen 307 and is discharged from the discharge port into the extraction mechanism 400. The filter screen 307 in this invention is preferably a 200-mesh titanium alloy screen, so that the sample can pass through the filter screen after being ground to a particle size of 75μm.

[0060] like Figure 5As shown, a positioning ring platform 308 is provided on the inner wall of the grinding outer cavity 302, and a positioning ring groove 309 is provided on the grinding inner cavity 303; the positioning ring platform 308 and the positioning ring groove 309 are compatible; when installing the grinding inner cavity 303, the grinding inner cavity 303 can be placed in the grinding outer cavity 302 through the cooperation of the positioning ring platform 308 and the positioning ring groove 309, and the grinding inner cavity 303 can be quickly positioned through the cooperation of the positioning ring platform 308 and the positioning ring groove 309; it should be noted that there is a gap between the outer wall of the grinding inner cavity 303 and the inner wall of the grinding outer cavity 302, and an annular groove is opened on the outer wall of the grinding inner cavity 303. A rubber ring is placed in the annular groove, and the gap between the grinding inner cavity 303 and the grinding outer cavity 302 is filled by the rubber ring, which can buffer the lateral force of the grinding inner cavity 303 on the grinding outer cavity 302 during the grinding stage.

[0061] In addition, a grinding solenoid valve 801 is provided at the outlet position of the grinding outer cavity 302, and a wire hole is opened on the grinding outer cavity 302. The grinding solenoid valve 801 is connected to the controller 700 through the control line. During grinding, the solenoid valve is in the closed state. When grinding is completed, the solenoid valve is opened by the controller 700, and the sample temporarily stored at the outlet position will fall into the extraction mechanism 400 after passing through the outlet.

[0062] like Figure 4 , 7 As shown in Figure 8, the extraction mechanism 400 includes an outer extraction cavity 402 and an inner extraction cavity 403. The inner extraction cavity 403 is placed inside the outer extraction cavity 402, and a thick PFA coating is sprayed onto the inner surface of the inner extraction cavity 403. A heating layer 404 is sleeved on the outer surface of the inner extraction cavity 403. A through hole is provided on the outer extraction cavity 402, and the heating layer 404 and the controller 700 are connected through a control line. The extraction cavity cover 405 is connected to the outer extraction cavity 402. A first connection port 451, a second connection port 452, and a third connection port 453 are provided on the extraction cavity cover 405. The first connection port 451 is connected to the first storage bottle 601 through a conduit, and the second connection port 452 is connected to the outer extraction cavity 602 through a conduit. The sample is connected to the second storage bottle 602 via a conduit, and the third connection port 453 is connected to the nitrogen cylinder via a gas tube. Several detection ports are opened on the extraction chamber cover 405, and several detection tubes are set in the detection ports. In addition, the connecting cylinder 803 is inserted into the extraction chamber cover 405 and communicates with the extraction chamber 403. The sample ground by the grinding mechanism 300 falls into the extraction chamber 403 under its own gravity through the connecting cylinder 803, and the grinding solenoid valve 801 is closed by the controller 700. Acid and buffer solution are delivered to the extraction chamber 403 through the first storage bottle 601 and the second storage bottle 602, and the sample, acid and buffer solution are extracted in the extraction chamber 403.

[0063] In addition, during the extraction process, nitrogen gas is supplied to the third connection port 453 through a nitrogen cylinder. The nitrogen gas isolates the extraction chamber 403 from air, preventing sample oxidation. A pressure sensor 463 is installed on the extraction chamber cover 405, and a solenoid valve is installed on the third connection port 453, both connected to the controller 700 via control lines. The pressure sensor acquires the pressure within the extraction chamber 403. When the pressure is too high, the controller 700 closes the solenoid valve on the third connection port 453 to prevent excessive pressure in the extraction chamber 403. Of course, depending on the pressure conditions, adjustments can be made by setting... Excess nitrogen gas is discharged to the outside through the pressure valve on the extraction chamber cover 405. Additionally, this invention has two detection ports, with a temperature sensor 461 and a liquid level sensor 462 respectively installed in each port. The temperature sensor 461 detects the temperature inside the extraction chamber 403, and the liquid level sensor 462 detects the liquid level inside the extraction chamber 403. Both the temperature sensor 461 and the liquid level sensor 462 are connected to the controller 700 via control lines. The temperature sensor 461 collects the temperature inside the extraction chamber 403 in real time, and the controller 700 controls the heating layer 404 to start and stop after receiving the data.

[0064] In addition, a liquid outlet solenoid valve is installed on the liquid outlet pipe 802. The liquid outlet solenoid valve is connected to the controller 700 via a control line. At the same time, the bottom of the extraction chamber 403 is inclined towards the location of the liquid outlet pipe 802 to ensure that the solvent in the extraction chamber 403 can flow towards the location of the liquid outlet pipe 802 during the liquid outlet stage. After the extraction is completed, when the solvent in the extraction chamber 403 is discharged to the detection mechanism 500 through the liquid outlet pipe 802, the liquid level sensor 462 detects the solution status in the extraction chamber 403, and the controller 700 controls the liquid outlet solenoid valve to close through the detection interface of the liquid level sensor 462.

[0065] In this invention, to ensure sufficient extraction of the sample within the extraction chamber 403, a stirring body 471 and a driving body 472 are preferably provided. The stirring body 471 is disposed within the extraction chamber 403; the driving body 472 is disposed within the extraction outer chamber 402 and is magnetically connected to the stirring body 471. The driving body 472 is connected to the controller 700 via a control line passing through a through-hole in the extraction outer chamber 402. The controller 700 controls the starting and stopping of the driving body 472, and under the action of the driving body 472, the stirring body 471 agitates the solvent in the extraction chamber 403. This improves the extraction effect. Preferably, the stirring element 471 is a PTFE-coated neodymium iron boron magnet, and the driving element 472 is a permanent magnet synchronous magnetic coupling drive motor. Through the magnetic coupling between the driving element 472 and the stirring element 471, the stirring element 471 rotates within the extraction cavity 403, thereby thoroughly mixing the solvent within the extraction cavity 403. Of course, the rotation frequency of the stirring element 471 can be set according to actual conditions. It can be controlled by the controller 700 to rotate the stirring element 471 forward or backward for 1 minute every 5 minutes. The specific frequency depends on the actual situation, and this invention does not further limit it.

[0066] like Figure 4 As shown, to ensure the stability of the extraction inner cavity 403 and the extraction outer cavity 402, in this invention, an annular support plate 481 is provided on the inner wall of the extraction outer cavity 402, and an annular pressure plate 482 is provided on the outer surface of the extraction inner cavity 403. The annular support plate 481 and the annular pressure plate 482 are compatible. During the installation stage, after the extraction inner cavity 403 is installed into the extraction outer cavity 402, the annular support plate 481 and the annular pressure plate 482 cooperate to limit the extraction inner cavity 403 in the extraction outer cavity 402, thereby improving the stability of the extraction inner cavity 403 in the extraction outer cavity 402. In addition, a sealing ring (such as a fluororubber ring) is provided between the extraction cavity cover 405 and the top of the extraction inner cavity 403 to increase the sealing of the extraction inner cavity 403 and prevent gas in the extraction outer cavity 402 from entering the extraction inner cavity 403 through the gap between the extraction cavity cover 405 and the extraction inner cavity 403.

[0067] In addition, the heating layer 404 is placed on both sides of the annular support plate 481 and the annular pressure plate 482, and a heat insulation layer 409 is provided between the heating layer 404 and the inner wall of the extraction outer cavity 402. The heat insulation layer 409 can prevent the heat generated by the heating layer 404 from exchanging heat with the extraction outer cavity 402, thereby improving the heating effect of the extraction inner cavity 403. The preferred heat insulation layer 409 is ceramic fiber heat insulation cotton.

[0068] like Figure 4 and Figure 7As shown, the detection mechanism 500 includes a detection outer cavity 501 and a detection frame 502 disposed within the detection outer cavity 501; a first detection tube 503 and a second detection tube 504 are disposed on the detection frame 502 and are respectively connected to a first diversion valve 505 via conduits; the first diversion valve 505 is connected to an outlet pipe 802; a second diversion valve 506 is connected to the first detection tube 503 and the second detection tube 504 via a drain pipe; and a first detection body 507 and a second detection body 508 are respectively disposed at the connection points of the first detection tube 503 and the second detection tube 504 with the drain pipe; a plurality of waste liquid collection bottles 591 are disposed at the bottom of the detection outer cavity 501 and are connected to the second diversion valve 506 via a plurality of waste liquid pipes;

[0069] After extraction, the solvent flows through the outlet pipe 802 to the first diversion valve 505, and then through the first diversion valve 505 into the first detection tube 503 and the second detection tube 504. After passing through the first detection tube 503 and the second detection tube 504, it enters the second diversion valve 506, and through the second diversion valve 506, the tested liquid is discharged into the waste liquid pipe, and through the waste liquid pipe, the liquid is discharged into the waste liquid collection bottle 591. In addition, during the discharge process, the pH value in the first detection tube 503 and the second detection tube 504 is detected by the first detection body 507 and the second detection body 508, respectively, and the detection results are sent to the controller 700, which then displays the detection results. Specifically, the first detection body 507 and the second detection body 508 are respectively equipped with pH electrode sensors, which are inserted into the solvent and detect the pH value in the solvent as it flows. If the pH value is less than 6 or greater than 8, the controller 700 will trigger an alarm (buzzer) to indicate that the detection result does not meet the requirements and stop the detection.

[0070] It should be noted that a flow meter is installed at the inlet end of both the first detection tube 503 and the second detection tube 504. The flow meter is connected to the controller 700 after passing through a through hole in the detection outer cavity 501 with a wire. The controller 700 acquires the flow data of the flow meter and controls the opening and closing of the first diversion valve 505, thereby controlling the amount of solution entering the first detection tube 503 and the second detection tube 504. The first detection tube 503 and the second detection tube 504 are respectively an SCX cation exchange column and an SAX anion exchange column, and both the first detection tube 503 and the second detection tube 504 are made of PFA material. At the same time, the first detection tube 503 contains... The first detection tube 503 is filled with a strong cation exchange resin, and the second detection tube 504 is filled with a styrene-divinylbenzene copolymer strong anion exchange resin. PTFE sieve plates are installed at both ends of the first and second detection tubes 503 and 504 to prevent the exchange resin from leaking out. It should be noted that when testing through the first and second detection tubes 503 and 504, the specifications of the first and second detection tubes 503 and 504 are a length of 10 cm and an inner diameter of 4.6 mm. The flow rate within the first and second detection tubes 503 and 504 is controlled at 1 ml / min by the internal exchange resin.

[0071] In addition, the first diversion valve 505 and the second diversion valve 506 are a three-way solenoid valve and a six-way solenoid valve, respectively, and are connected to the controller 700 via control lines. The controller 700 controls the first diversion valve 505 and the second diversion valve 506, thereby better controlling the amount of solvent entering the first detection tube 503, the second detection tube 504, and several waste liquid collection bottles. In this utility model, four waste liquid collection bottles 591 are preferably provided, and the controller 700 controls the second diversion valve 506 to input solvent into the four waste liquid collection bottles 591 respectively. At the same time, a weighing sensor 592 is separately provided at the bottom of each of the four waste liquid collection bottles 591. Sensors 592 are connected to controller 700 via control lines. The load cell 592 detects the amount of solvent in waste liquid collection bottle 591 in real time and transmits the acquired data to controller 700. Specifically, when a waste liquid collection bottle 591 is full (the load cell 592 acquires the weight and sends the acquired weight data to controller 700), controller 700 controls the second diversion valve 506 to adjust its conduction so that the next waste liquid collection bottle 591 can receive waste liquid, and the previous waste liquid collection bottle 591 stops receiving waste liquid. After all four waste liquid collection bottles 591 are full of waste liquid, the waste liquid collection bottles 591 are replaced or cleaned.

[0072] It should be noted that in this utility model, the internal components of the extraction mechanism 400 and the detection mechanism 500 need to be treated with anti-corrosion or coated with anti-corrosion coating to avoid being corroded during use. Since the existing technology is used, this utility model will not be described further.

[0073] The working process of this utility model is as follows: The controller 700 controls the drive device 200 to operate, and drives the grinding head 306 in the grinding mechanism 300 to grind the sample entering the grinding chamber 303; at the same time, the controller 700 controls the nitrogen cylinder to deliver nitrogen into the extraction chamber 403, and discharges the air in the extraction chamber 403 through the pressure valve; 10 seconds after the grinding is completed, the controller opens the grinding solenoid valve 801 on the grinding mechanism 300, so that the ground sample enters the extraction mechanism 400; during the extraction process, the extraction chamber 403 is kept in a slightly positive nitrogen pressure state; the controller 700 acquires the real-time temperature and pressure of the temperature sensor 461 and the pressure sensor 463, and controls the nitrogen cylinder and the heating layer 404 according to the received data; after the extraction is completed, the controller 700 controls the first diversion valve 505 to open, and discharges the sample through the liquid outlet pipe 802. The extracted solvent is transferred to the first detection tube 503 and the second detection tube 504. After the solvent flows through the first detection tube 503 and the second detection tube 504, the first detector 507 and the second detector 508 detect the solvent respectively to obtain the required detection results. At the same time, the controller 700 adjusts the second diversion valve 506 so that the detected solvent enters the waste liquid collection bottle in sequence. The controller 700 obtains the weight of the waste liquid collection bottle in real time and switches the second diversion valve 506 according to the result to ensure that after the waste liquid collection bottle is full, it can continue to store solvent through another waste liquid collection bottle. When all waste liquid collection bottles are full, the controller 700 obtains the weight signal and sounds an alarm to prompt the replacement of the waste liquid collection bottle. Preferably, a buzzer is provided, which can be controlled by the controller 700 to sound an alarm to prompt the replacement of the waste liquid collection bottle.

[0074] It should be noted that the outer detection chamber 501 is equipped with a detection chamber cover. When it is necessary to replace the waste liquid collection bottle, the detection chamber cover is separated from the outer detection chamber 501, and the detection frame 502 is removed before replacing the waste liquid collection bottle.

[0075] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of this utility model, and are not intended to limit it. Although the utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some or all of the technical features therein. Such modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of this utility model.

Claims

1. A sample extraction device for mineral drug detection, characterized in that, include: A fixing frame (100) and a driving device (200) mounted on the fixing frame (100); A grinding mechanism (300) for grinding and screening samples is provided on the fixed frame (100), and the output shaft of the drive device (200) passes through the top of the grinding mechanism (300) and is placed inside the grinding mechanism (300); An extraction mechanism (400) for extracting the ground sample is mounted on the fixed frame (100) and placed below the grinding mechanism (300), and the grinding mechanism (300) and the extraction mechanism (400) are connected by a connecting tube (803); A detection mechanism (500) for detecting the solvent containing the sample after extraction is set on the fixture (100), and the extraction mechanism (400) and the detection mechanism (500) are connected through a liquid outlet pipe (802); A first storage bottle (601) and a second storage bottle (602) for respectively inputting acid and buffer solution into the extraction mechanism (400) are respectively mounted on the fixing frame (100); The controller (700) is mounted on the fixed frame (100) and is electrically connected to the drive device (200), grinding mechanism (300), extraction mechanism (400), detection mechanism (500), first storage bottle (601) and second storage bottle (602).

2. The mineral drug detection sample extraction device according to claim 1, characterized in that, The fixing frame (100) is provided with a plurality of first fixing plates (101) and a plurality of second fixing plates (102), and the grinding mechanism (300) and the extraction mechanism (400) are each provided with a plurality of first connecting plates (301) and a plurality of second connecting plates (401); the plurality of first fixing plates (101) and the plurality of first connecting plates (301) are fixed by bolts; the plurality of second fixing plates (102) and the plurality of second connecting plates (401) are fixed by bolts.

3. The mineral drug detection sample extraction device according to claim 1, characterized in that, The drive device (200) is mounted on the mounting bracket (103) on the fixed frame (100); and the output shaft of the drive device (200) includes a first section (201) and a second section (202); the first section (201) and the second section (202) are connected by a coupling (203); and the second section (202) passes through the bearing seat (204) provided on the grinding mechanism (300) and is placed inside the grinding mechanism (300).

4. The mineral drug detection sample extraction device according to claim 1, characterized in that, The grinding mechanism (300) includes: The grinding chamber (302) and the grinding chamber (303) are provided, wherein the grinding chamber (303) is disposed within the grinding chamber (302); and the outlet of the grinding chamber (303) corresponds to the outlet of the grinding chamber (302). The grinding chamber cover (304) is connected to the grinding outer chamber (302); and the grinding chamber cover (304) is provided with a feed inlet (305); A grinding head (306) is placed inside the grinding cavity (303), and the output shaft of the drive device (200) is connected to the grinding head (306); A filter screen (307) is disposed in the grinding cavity (303).

5. The mineral drug detection sample extraction device according to claim 4, characterized in that, The inner wall of the grinding outer cavity (302) is provided with a positioning ring platform (308), and the grinding inner cavity (303) is provided with a positioning ring groove (309); the positioning ring platform (308) and the positioning ring groove (309) are adapted to each other.

6. The mineral drug detection sample extraction device according to claim 1, characterized in that, The extraction mechanism (400) includes: An extraction outer cavity (402) and an extraction inner cavity (403) are provided, wherein the extraction inner cavity (403) is placed inside the extraction outer cavity (402); and a heating layer (404) is provided on the outer surface of the extraction inner cavity (403); An extraction chamber cover (405) is connected to the extraction outer chamber (402); and a first connection port (451), a second connection port (452) and a third connection port (453) are provided on the extraction chamber cover (405); the first connection port (451) is connected to the first storage bottle (601) through a conduit, the second connection port (452) is connected to the second storage bottle (602) through a conduit, and the third connection port (453) is connected to the nitrogen cylinder through a gas pipe; Several detection ports are provided on the extraction chamber cover (405), and several detection tubes are provided in the several detection ports.

7. The mineral drug detection sample extraction device according to claim 6, characterized in that, The extraction mechanism (400) also includes: A stirring element (471) is disposed within the extraction cavity (403); The driving body (472) is disposed in the extraction outer cavity (402) and is magnetically connected to the stirring body (471).

8. The mineral drug detection sample extraction device according to claim 6, characterized in that, An annular support plate (481) is provided on the inner wall of the extraction outer cavity (402), and an annular pressure plate (482) is provided on the outer surface of the extraction inner cavity (403). The annular support plate (481) and the annular pressure plate (482) are adapted to each other.

9. The mineral drug detection sample extraction device according to claim 8, characterized in that, The heating layer (404) is placed on both sides of the annular support plate (481) and the annular pressure plate (482), and a heat insulation layer (409) is provided between the heating layer (404) and the inner wall of the extraction outer cavity (402).

10. The mineral drug detection sample extraction device according to claim 1, characterized in that, The testing facility (500) includes: The detection outer cavity (501) and the detection frame (502) disposed within the detection outer cavity (501); The first detection tube (503) and the second detection tube (504) are disposed on the detection frame (502) and are respectively connected to the first diversion valve (505) through conduits; the first diversion valve (505) is connected to the liquid outlet tube (802); The second diversion valve (506) is connected to the first detection tube (503) and the second detection tube (504) respectively through the drain pipe; and a first detection body (507) and a second detection body (508) are respectively provided at the connection between the first detection tube (503) and the second detection tube (504) and the drain pipe. Several waste liquid collection bottles (591) are set at the bottom of the detection outer cavity (501) and are connected to the second diversion valve (506) through several waste liquid pipes.

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