A mouse-tail photic pain measuring instrument

Abstract

The utility model discloses a mouse tail light pain measuring instrument, including test platform, one side of test platform upper end is equipped with mouse fixed cylinder, the rear side of test platform upper end is equipped with connecting frame, the upper end of connecting frame is equipped with laser generator, the one side array of mouse fixed cylinder is equipped with a plurality of fixed blocks, and the middle portion of fixed block is equipped with the movable column of going through, one end of movable column inside is connected with movable plate, and the periphery of movable plate one end surface is connected with spring, and one end of movable plate is fixedly connected with connecting column. The utility model discloses through the slit between two movable plates of the tail of experimental mouse, then the mouse tail will be clamped between two pressure dynamic plates, and the spring in the inner chamber inside will push movable plate to the outside with the elasticity, and movable plate and connecting column and pressure dynamic plate move outward, make two pressure dynamic plates can carry out the clamping operation to the tail of mouse through the setting, to avoid the mouse tail to sway on the end face of test platform.

Description

Technical Field

[0001] This utility model relates to the technical field of rat tail light-induced pain measurement devices, specifically a rat tail light-induced pain measurement device. Background Technology

[0002] The rat tail photothermal analgesia device works by shining a beam of light onto the rat's tail to generate heat, causing localized temperature increases and pain. When the pain exceeds the animal's pain threshold, the animal will effectively flick its tail to escape. This method of determining the level and changes in an animal's pain threshold is called the photothermal tail-flick method. When the animal feels pain, its tail will tap the table lightly. The built-in sensor will immediately detect this, stopping the timer and turning off the light source. The instrument automatically records the reaction time and light intensity, and the data can be exported via USB flash drive. The instrument contains an adjustable-intensity infrared light source, which is focused onto the animal's tail through a parabolic reflector. During the experiment, the operator places the animal on the instrument and positions its tail at the infrared light source to receive the stimulation.

[0003] However, in existing rat tail photothermal analgesia experiments, the experimental platform only positions the rat's body, without positioning the rat's tail in a lateral plane. This causes the rat's tail to swing laterally when not positioned, which means that the infrared laser emitted by the laser generator may not accurately illuminate the rat's tail. Ultimately, this results in inaccurate data measured by the continuity tester, thus failing to meet current requirements. To address this, we propose a rat tail photothermal analgesia device. Utility Model Content

[0004] The purpose of this invention is to provide a rat tail photothermal analgesia device to solve the problem mentioned in the background art that in the existing rat tail photothermal analgesia experiment, the experimental platform only positions the rat's body and does not position the rat's tail in a horizontal plane. This causes the rat's tail to swing laterally when it is not positioned, which in turn causes the infrared laser emitted by the laser generator to be unable to accurately illuminate the rat's tail, ultimately resulting in inaccurate data measured by the analgesia device.

[0005] To achieve the above objectives, this utility model provides the following technical solution: a rat tail phototherapy pain meter, comprising a testing platform, a rat fixing cylinder on one side of the upper end of the testing platform, a connecting frame on the rear side of the upper end of the testing platform, a laser generator on the upper end of the connecting frame, multiple fixing blocks arranged in an array on one side of the rat fixing cylinder, a movable column penetrating through the middle of the fixing block, a movable plate connected to one end of the movable column, springs connected around one end face of the movable plate, a connecting column fixedly connected to one end of the movable plate, a pressure plate fixedly connected to one end of the connecting column, and through holes penetrating through both ends of the fixing block, with the movable column and connecting column moving within the through holes.

[0006] Preferably, one end face of the two pressing plates near the mouse fixing cylinder is provided with a squeezing block, and one end face of the other two pressing plates is a smooth plane.

[0007] Preferably, one end of the spring is connected to the movable plate, and the other end face of the spring is connected to the end face inside the inner cavity.

[0008] Preferably, the extrusion block is made of a soft material.

[0009] Preferably, an inner baffle plate is threadedly connected to one side of the inside of the mouse fixing tube.

[0010] Preferably, both the front and rear ends of the other side of the mouse fixing tube are fixedly connected to a stop block, and a movable plate is movably provided on one side of the stop block, and a spring piece is fixedly connected to one end of the movable plate.

[0011] Preferably, one end of the spring is fixedly connected to the inner wall of the mouse fixing cylinder, and the cross-section of the spring is designed as a curved surface.

[0012] Compared with the prior art, the beneficial effects of this utility model are:

[0013] 1. This utility model involves inserting the tail of an experimental mouse through the gap between two movable plates. The mouse's tail is then clamped between two pressure plates. A spring inside the inner cavity provides an elastic force, which pushes the movable plate outward. This pushes the movable plate, the connecting column, and the pressure plates outward. This design allows the two pressure plates to clamp the mouse's tail, preventing it from swaying on the end face of the testing platform. Then, the experimenter turns on the power of the laser generator on the connecting frame, which irradiates the mouse's tail with a laser and performs a pain measurement experiment on the mouse's tail.

[0014] 2. This utility model involves placing food that attracts laboratory mice inside an inner baffle. The experimenter then places the mice on the top of a testing platform. The mice will be attracted by the food inside the inner baffle and will autonomously crawl into the mouse-fixing tube through two movable plates. The movable plates are equipped with spring clips facing the inner baffle. When the movable plates are subjected to force, the spring clips will bend and the block will block the rotation of the movable plates, so that the movable plates can only face the inside of the mouse-fixing tube. This prevents the laboratory mice that have entered the mouse-fixing tube from opening inside. Attached Figure Description

[0015] Figure 1 This is a three-dimensional structural diagram of the entire utility model;

[0016] Figure 2This is a top sectional view of the entire utility model;

[0017] Figure 3 This utility model Figure 2 Enlarged cross-sectional view at point A in the middle;

[0018] Figure 4 This utility model Figure 2 Enlarged cross-sectional view at point B.

[0019] In the diagram: 1. Mouse fixing cylinder; 2. Test platform; 3. Connecting frame; 4. Laser generator; 5. Fixing block; 6. Movable column; 7. Pressing plate; 8. Extrusion block; 9. Inner cavity; 10. Through hole; 11. Spring; 12. Movable plate one; 13. Connecting column; 14. Inner baffle plate; 15. Movable plate two; 16. Spring piece; 17. Stop block. Detailed Implementation

[0020] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present utility model. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments.

[0021] Please see Figures 1 to 4 An embodiment of this utility model provides a rat tail phototherapy pain meter, including a test platform 2, a rat fixing cylinder 1 on one side of the upper end of the test platform 2, a connecting frame 3 on the rear side of the upper end of the test platform 2, a laser generator 4 on the upper end of the connecting frame 3, the laser generator 4 can emit laser to irradiate the rat's tail, a plurality of fixing blocks 5 are arranged in an array on one side of the rat fixing cylinder 1, a movable column 6 is provided through the middle of the fixing block 5, a movable plate 12 is connected to one end of the movable column 6, a spring 11 is connected around one end face of the movable plate 12, a connecting column 13 is fixedly connected to one end of the movable plate 12, a pressing plate 7 is fixedly connected to one end of the connecting column 13, and through holes 10 are provided at both ends of the fixing block 5, the movable column 6 and the connecting column 13 move within the through holes 10;

[0022] Two pressure plates 7 near the mouse fixing cylinder 1 have a squeezing block 8 on one end face. The other two pressure plates 7 have a smooth flat surface on one end face. One end of the spring 11 is connected to the movable plate 12, and the other end face of the spring 11 is connected to the end face inside the inner cavity 9. The squeezing block 8 is made of soft material. This arrangement avoids the pressure plates 7 and squeezing block 8 being too hard, thus avoiding damage to the mouse when clamping its tail.

[0023] One side of the mouse-fixing cylinder 1 is connected to an inner baffle plate 14 by a thread. Both the front and rear ends of the other side of the mouse-fixing cylinder 1 are fixedly connected to a stop block 17. A movable plate 15 is movably provided on one side of the stop block 17. A spring piece 16 is fixedly connected to one end of the movable plate 15. One end of the spring piece 16 is fixedly connected to the inner wall of the mouse-fixing cylinder 1. The cross-section of the spring piece 16 is a curved structure. The movable plate 15 and the inner end face of the mouse-fixing cylinder 1 are connected by a hinge, so that the movable plate 15 can rotate inside the mouse-fixing cylinder 1. The stop block 17 blocks the rotation of the movable plate 15, which causes the stop block 17 to rotate in the direction of the inner spring piece 16. The spring piece 16 is made of elastic metal.

[0024] The inner surface of the mouse fixing tube 1 is provided with internal threads, and the outer surface of the inner baffle 14 is provided with external threads. The inner baffle 14 is fixedly connected to the inside of the mouse fixing tube 1 by the threads. Food that attracts experimental mice is placed inside the inner baffle 14. Then, the experimenter places the mouse on the upper end of the test platform 2. The experimental mouse will be attracted by the food inside the inner baffle 14. The experimental mouse will autonomously crawl into the inside of the mouse fixing tube 1 through the two movable plates 15. The movable plates 15 are provided with spring pieces 16 in the direction facing the inner baffle 14. When the movable plates 15 are subjected to force, they will press and bend the spring pieces 16. Then, the elastic force of the two spring pieces 16 will push the movable plates 15 back to the original position.

[0025] By setting a stop 17 on the other side of the movable plate 2 15, the stop 17 blocks the rotation of the entire movable plate 2 15, so that the movable plate 2 15 can only face the inside of the mouse fixing tube 1, rather than the outside of the mouse fixing tube 1. This prevents the experimental mouse that has entered the mouse fixing tube 1 from opening inside the mouse fixing tube 1. Therefore, the two movable plates 2 15 in this setting can keep the experimental mouse inside the mouse fixing tube 1.

[0026] Next, the experimenter inserted the tail of the experimental mouse through the gap between the two movable plates 15. The mouse's tail was then clamped between the two pressing plates 7. The spring 11 inside the inner cavity 9 provided the stretching force. The force of the spring 11 pushed the movable plate 12 outward. This force of the spring 11 pushed the movable plate 12, the connecting column 13, and the pressing plates 7 outward. This arrangement enabled the two pressing plates 7 to clamp the mouse's tail. At the same time, there were compression blocks 8 on the surface of the pressing plates 7. This arrangement made the material clamping the mouse's tail soft, avoiding damage to the mouse's tail when clamping it.

[0027] Two opposing pressure plates 7 clamp the mouse's tail, allowing it to be positioned laterally on the test platform 2, thus preventing the mouse's tail from wobbling on the end face of the test platform 2. Then, the experimenter turns on the power of the laser generator 4 on the connecting frame 3, and the laser generator 4 is powered on to irradiate the mouse's tail with a laser, and a pain measurement experiment of the mouse's tail is conducted.

[0028] If the clamping plate 7 loosens the grip on the mouse's tail, the movable column 6 is pulled outward, causing the movable column 6 to move the internal movable plate 12. The movable plate 12 then moves laterally into the inner cavity 9, overcoming the stretching force of the spring 11. This causes the movable plate 12 to move the outer connecting column 13 and the clamping plate 7, so that the two clamping plates 7 no longer clamp the mouse. Finally, the entire inner shielding plate 14 is rotated from the inside of the mouse fixing tube 1 to the outside, allowing the experimental mouse inside the mouse fixing tube 1 to escape, and the experiment ends.

[0029] It will be apparent to those skilled in the art that this invention is not limited to the details of the exemplary embodiments described above, and that it can be implemented in other specific forms without departing from the spirit or essential characteristics of this invention. Therefore, the embodiments should be considered illustrative and non-limiting in all respects, and the scope of this invention is defined by the appended claims rather than the foregoing description. Thus, it is intended that all variations falling within the meaning and scope of equivalents of the claims be included within this invention. No reference numerals in the claims should be construed as limiting the scope of the claims.

Claims

1. A rat tail photoluminescence pain meter, comprising a testing platform (2), characterized in that: The test platform (2) has a mouse fixing tube (1) on one side of its upper end, a connecting frame (3) on the rear side of its upper end, a laser generator (4) on the upper end of the connecting frame (3), a plurality of fixing blocks (5) arranged in an array on one side of the mouse fixing tube (1), a movable column (6) penetrating through the middle of the fixing block (5), a movable plate (12) connected to one end of the movable column (6), a spring (11) connected around one end face of the movable plate (12), a connecting column (13) fixedly connected to one end of the movable plate (12), a pressing plate (7) fixedly connected to one end of the connecting column (13), and through holes (10) penetrating through both ends of the fixing block (5), with the movable column (6) and the connecting column (13) moving within the through holes (10). One end face of the two pressing plates (7) near the mouse fixing cylinder (1) is provided with a squeezing block (8), and the other two pressing plates (7) have a smooth flat surface on one end face; One end of the spring (11) is connected to the movable plate (12), and the other end face of the spring (11) is connected to the end face inside the inner cavity (9); The extrusion block (8) is made of a soft material; An inner baffle plate (14) is threadedly connected to one side of the inside of the mouse fixing tube (1). Both the front and rear ends of the other side of the mouse fixing tube (1) are fixedly connected to a stop block (17). A movable plate (15) is movably provided on one side of the stop block (17), and a spring piece (16) is fixedly connected to one end of the movable plate (15).

2. The rat tail phototherapy pain meter according to claim 1, characterized in that: One end of the spring piece (16) is fixedly connected to the inner wall of the mouse fixing cylinder (1), and the cross-section of the spring piece (16) is set as a curved surface structure.

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