A chromatographic column system for separating polysaccharides from lentinan concentrate

Abstract

The utility model discloses a kind of chromatography column systems for separating polysaccharide from lentinus edodes concentrated solution, it is related to separation and purification instrument technical field, including bottom plate and chromatography column main body, the chromatography column main body is set to the top of bottom plate, the upper surface of bottom plate and located the side fixed of chromatography column main body is equipped with vertical plate, the upper end of vertical plate is equipped with square hole, the inside of square hole is equipped with square bar slidingly, the side fixed of square bar close to chromatography column main body is equipped with U-shaped plate, both ends of U-shaped plate are equipped with through-hole, both ends of chromatography column main body are passed through corresponding through-hole, the middle part of U-shaped plate is equipped with limiting mechanism for limiting chromatography column main body relative to U-shaped plate movement, the outer wall of vertical plate is equipped with transmission mechanism for driving square bar movement. The utility model can automatically shake chromatography column main body, so that the filler in chromatography column main body is evenly distributed, guarantee separation effect.

Description

Technical Field

[0001] This utility model relates to the field of separation and purification instrument technology, specifically to a chromatography column system for separating polysaccharides from shiitake mushroom concentrate. Background Technology

[0002] In the separation of polysaccharides from shiitake mushroom concentrate, chromatography columns are commonly used separation equipment. The uniform distribution of the packing material within the chromatography column plays a crucial role in the separation efficiency of polysaccharides.

[0003] Currently, most chromatography columns suffer from uneven packing material distribution after loading, leading to inconsistent flow paths of the shiitake mushroom concentrate within the column and affecting the purity and efficiency of polysaccharide separation. Existing solutions typically involve manually shaking the column to ensure uniform packing distribution. However, this method is labor-intensive, and the intensity and frequency of shaking are difficult to control, making it impossible to guarantee uniform packing distribution each time, thus impacting polysaccharide separation. Utility Model Content

[0004] In view of the problems existing in the chromatography column system for separating polysaccharides from shiitake mushroom concentrate, this utility model is proposed.

[0005] Therefore, the purpose of this invention is to provide a chromatography column system for separating polysaccharides from shiitake mushroom concentrate, which solves the problems mentioned in the background art.

[0006] To achieve the above objectives, this utility model provides the following technical solution:

[0007] A chromatography column system for separating polysaccharides from shiitake mushroom concentrate includes a base plate and a chromatography column body. The chromatography column body is disposed above the base plate. A vertical plate is fixedly disposed on the upper surface of the base plate and on one side of the chromatography column body. A square hole is opened at the upper end of the vertical plate. A square rod is slidably disposed inside the square hole. A U-shaped plate is fixedly disposed on the side of the square rod near the chromatography column body. Both ends of the U-shaped plate have through holes. Both ends of the chromatography column body pass through the corresponding through holes. A limiting mechanism is provided in the middle of the U-shaped plate to restrict the movement of the chromatography column body relative to the U-shaped plate. A transmission mechanism is provided on the outer wall of the vertical plate to drive the square rod to move.

[0008] Preferably, the limiting mechanism includes an internally threaded tube and a limiting tube. The internally threaded tube is fixedly installed at the middle end of the U-shaped plate and on the side close to the main body of the chromatography column. The threaded rod is threaded into the inside of the internally threaded tube. The limiting tube is fixedly installed on the side of the main body of the chromatography column close to the threaded rod. One end of the threaded rod extends into the inside of the limiting tube.

[0009] Preferably, the transmission mechanism includes a turntable and a movable frame. The movable frame is fixedly disposed at the end of the square rod away from the U-shaped plate. The turntable is disposed below the movable frame. A side plate is disposed below the turntable. One end of the side plate is fixedly connected to the vertical plate. A rotating rod is rotatably disposed on the upper surface of the side plate. The upper end of the rotating rod is fixedly connected to the middle of the turntable. A motor is fixedly disposed on the lower surface of the side plate. The output end of the motor is fixedly connected to one end of the rotating rod. A round pin is eccentrically disposed on the upper surface of the turntable. The upper end of the round pin passes through the movable frame.

[0010] Preferably, a clearance groove is provided at the lower end of the U-shaped plate at a position corresponding to the limiting tube.

[0011] Preferably, the upper end of the round pin is fixedly sleeved with an anti-detachment ring.

[0012] Preferably, the square rod has a spring movably sleeved on its wall, and the two ends of the spring are fixedly connected to the corresponding U-shaped plate and vertical plate, respectively.

[0013] The technical effects and advantages provided by this utility model in the above technical solution are as follows:

[0014] 1. This utility model uses a motor to drive a turntable to rotate, causing a round pin to rotate around a rotating rod as an axis. During this rotation, the round pin slides within a movable frame, which in turn pushes the movable frame to move. This, in turn, causes the square rod to move the U-shaped plate, which in turn causes the chromatography column to sway horizontally. This ensures that the packing material inside the chromatography column is shaken evenly, thus improving the performance.

[0015] 2. In this utility model, by rotating the threaded rod, the threaded rod retracts into the inner threaded tube, thus separating the threaded rod from the limiting tube. At this time, the limiting tube can be passed through the relief groove of the U-shaped plate, and the main body of the chromatography column can be removed from the U-shaped plate, which facilitates the maintenance of the chromatography column. Attached Figure Description

[0016] To more clearly illustrate the technical solutions in the embodiments of this application or the prior art, the drawings used in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments recorded in this utility model. For those skilled in the art, other drawings can be obtained based on these drawings.

[0017] Figure 1 This is a schematic diagram of the structure of a chromatography column system for separating polysaccharides from shiitake mushroom concentrate according to the present invention;

[0018] Figure 2 for Figure 1 Another structural diagram from a different perspective;

[0019] Figure 3 for Figure 1A magnified schematic diagram of part A in the middle section.

[0020] Explanation of reference numerals in the attached figures:

[0021] 1. Base plate; 2. Vertical plate; 3. U-shaped plate; 4. Chromatography column body; 5. Internally threaded tube; 6. Side plate; 7. Rotating rod; 8. Turntable; 9. Movable frame; 10. Round pin; 11. Square rod; 12. Spring; 13. Motor; 14. Limiting tube; 15. Threaded rod. Detailed Implementation

[0022] To enable those skilled in the art to better understand the technical solution of this utility model, the present utility model will be further described in detail below with reference to the accompanying drawings.

[0023] This utility model discloses a chromatography column system for separating polysaccharides from shiitake mushroom concentrate.

[0024] Reference Figure 1-3 A chromatography column system for separating polysaccharides from shiitake mushroom concentrate includes a base plate 1 and a chromatography column body 4. The chromatography column body 4 is positioned above the base plate 1. A vertical plate 2 is fixedly mounted on the upper surface of the base plate 1 and on one side of the chromatography column body 4. A square hole is opened at the upper end of the vertical plate 2. A square rod 11 is slidably mounted inside the square hole. A U-shaped plate 3 is fixedly mounted on the side of the square rod 11 near the chromatography column body 4. A spring 12 is movably sleeved on the rod wall of the square rod 11. The two ends of the spring 12 are fixedly connected to the corresponding U-shaped plate 3 and the vertical plate 2, respectively, so that the square rod 11 slides more smoothly. Both ends of the U-shaped plate 3 have through holes, and both ends of the chromatography column body 4 pass through the corresponding through holes. A limiting mechanism is provided in the middle of the U-shaped plate 3 to restrict the movement of the chromatography column body 4 relative to the U-shaped plate 3. A transmission mechanism is provided on the outer wall of the vertical plate 2 to drive the square rod 11 to move.

[0025] Reference Figure 1-3 The limiting mechanism includes an internally threaded tube 5 and a limiting tube 14. The internally threaded tube 5 is fixedly installed at the middle end of the U-shaped plate 3 and on the side close to the chromatography column body 4. The threaded rod 15 is threaded into the inside of the internally threaded tube 5. The limiting tube 14 is fixedly installed on the side of the chromatography column body 4 close to the threaded rod 15. One end of the threaded rod 15 extends into the inside of the limiting tube 14. An clearance groove is provided at the lower end of the U-shaped plate 3 and at the position corresponding to the limiting tube 14 to facilitate the passage of the limiting tube 14.

[0026] Reference Figure 1-3The transmission mechanism includes a turntable 8 and a movable frame 9. The movable frame 9 is fixedly set at the end of the square rod 11 away from the U-shaped plate 3. The turntable 8 is set below the movable frame 9. A side plate 6 is set below the turntable 8. One end of the side plate 6 is fixedly connected to the vertical plate 2. A rotating rod 7 is rotatably set on the upper surface of the side plate 6. The upper end of the rotating rod 7 is fixedly connected to the middle of the turntable 8. A motor 13 is fixedly set on the lower surface of the side plate 6. The output end of the motor 13 is fixedly connected to one end of the rotating rod 7. A round pin 10 is eccentrically set on the upper surface of the turntable 8. The upper end of the round pin 10 passes through the movable frame 9. An anti-detachment ring is fixedly sleeved on the upper end of the round pin 10 to prevent the round pin 10 from slipping out of the movable frame 9 as much as possible.

[0027] In this invention, during use, the two ends of the chromatography column body 4 are first passed through the through holes at both ends of the U-shaped plate 3, so that the chromatography column body 4 is located inside the U-shaped plate 3. Then, the threaded rod 15 is rotated to screw it inward along the internal threaded tube 5 until one end of the threaded rod 15 is inserted into the limiting tube 14, thereby fixing the chromatography column body 4 onto the U-shaped plate 3. Next, the motor 13 is started, and the motor 13 drives the rotating rod 7 to rotate. The rotating rod 7 drives the turntable 8 to rotate, and the eccentrically set round pin 10 on the turntable 8 rotates around the rotating rod 7. During the rotation, the round pin 10 slides in the movable frame 9, pushing the movable frame 9 to move left and right. The movable frame 9 drives the square rod 11 to slide left and right in the square hole of the vertical plate 2. The square rod 11 drives the U-shaped plate 3 and the chromatography column body 4 to sway left and right. During this process, the spring 12 extends and retracts with the movement of the square rod 11, playing a buffering and stabilizing role, making the swaying of the chromatography column body 4 more stable. Through the horizontal swaying of the chromatography column body 4, the packing material in it can be evenly distributed, ensuring the separation effect of polysaccharides from the shiitake mushroom concentrate. When maintenance is required on the chromatography column body 4, the threaded rod 15 is rotated in the opposite direction to allow it to exit from the limiting tube 14. Then, the chromatography column body 4 is lifted upward so that the limiting tube 14 passes through the clearance groove of the U-shaped plate 3, and the chromatography column body 4 can be removed from the U-shaped plate 3 for maintenance. After maintenance, it can be reinstalled according to the above steps.

[0028] The foregoing description only illustrates certain exemplary embodiments of the present invention. Undoubtedly, those skilled in the art can modify the described embodiments in various ways without departing from the spirit and scope of the present invention. Therefore, the above drawings and descriptions are illustrative in nature and should not be construed as limiting the scope of protection of the claims of the present invention.

Claims

1. A chromatography column system for separating polysaccharides from shiitake mushroom concentrate, comprising a base plate (1) and a chromatography column body (4), characterized in that, The chromatography column body (4) is positioned above the base plate (1). A vertical plate (2) is fixedly provided on the upper surface of the base plate (1) and on one side of the chromatography column body (4). A square hole is provided at the upper end of the vertical plate (2). A square rod (11) is slidably provided inside the square hole. A U-shaped plate (3) is fixedly provided on the side of the square rod (11) close to the chromatography column body (4). Both ends of the U-shaped plate (3) are provided with through holes. Both ends of the chromatography column body (4) pass through the corresponding through holes. A limiting mechanism is provided in the middle of the U-shaped plate (3) to restrict the movement of the chromatography column body (4) relative to the U-shaped plate (3). A transmission mechanism is provided on the outer wall of the vertical plate (2) to drive the square rod (11) to move.

2. The chromatography column system for separating polysaccharides from shiitake mushroom concentrate according to claim 1, characterized in that, The limiting mechanism includes an internally threaded tube (5) and a limiting tube (14). The internally threaded tube (5) is fixedly installed at the middle end of the U-shaped plate (3) and on the side close to the chromatography column body (4). The threaded rod (15) is threaded into the inside of the internally threaded tube (5). The limiting tube (14) is fixedly installed on the side of the chromatography column body (4) close to the threaded rod (15). One end of the threaded rod (15) extends into the inside of the limiting tube (14).

3. The chromatography column system for separating polysaccharides from shiitake mushroom concentrate according to claim 1, characterized in that, The transmission mechanism includes a turntable (8) and a movable frame (9). The movable frame (9) is fixedly set at the end of the square rod (11) away from the U-shaped plate (3). The turntable (8) is set below the movable frame (9). A side plate (6) is set below the turntable (8). One end of the side plate (6) is fixedly connected to the vertical plate (2). A rotating rod (7) is rotatably set on the upper surface of the side plate (6). The upper end of the rotating rod (7) is fixedly connected to the middle of the turntable (8). A motor (13) is fixedly set on the lower surface of the side plate (6). The output end of the motor (13) is fixedly connected to one end of the rotating rod (7). A round pin (10) is eccentrically set on the upper surface of the turntable (8). The upper end of the round pin (10) passes through the movable frame (9).

4. The chromatography column system for separating polysaccharides from shiitake mushroom concentrate according to claim 2, characterized in that, An avoidance groove is provided at the lower end of the U-shaped plate (3) and at the position corresponding to the limiting tube (14).

5. The chromatography column system for separating polysaccharides from shiitake mushroom concentrate according to claim 3, characterized in that, The upper end of the round pin (10) is fixedly sleeved with an anti-detachment ring.

6. The chromatography column system for separating polysaccharides from shiitake mushroom concentrate according to claim 1, characterized in that, The square rod (11) has a spring (12) movably sleeved on its wall. The two ends of the spring (12) are fixedly connected to the corresponding U-shaped plate (3) and vertical plate (2), respectively.

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