A filtration device for biosynthesis

Abstract

The utility model discloses a filter device for biological product synthesis, including filter frame, still including fixedly connected in the import of filter frame one end, fixedly connected in the export of filter frame other end, install the flow guide subassembly in the filter frame inside, fix the fixed strip on the filter frame inner wall, install the mounting frame on the filter frame, fixedly connected on the filter membrane body of mounting frame, install the mounting assembly on the filter frame and install the elastic component on the mounting assembly. Through five groups of mounting frame and filter membrane body from top to bottom are in the filter frame inside staggered distribution of ladder type, and filter membrane body filter hole is from top to bottom in turn 0.45um, 0.22um, 0.1um, 50nm, 10nm, cooperate flow guide subassembly and be accurate to the accurate flow guide conveying of biological product between filter membrane body, can complete multistage filtration one time, need not repeat operation many times, effectively simplify the filtration process, significantly improved the filtration efficiency and maintenance convenience, guarantee the continuity and purity of biological product filtration.

Description

Technical Field

[0001] This utility model relates to the field of filtration device technology, specifically a filtration device for the synthesis of biological products. Background Technology

[0002] Bioproduct synthesis refers to the process of synthesizing bioactive substances with specific functions by using biological systems such as microorganisms, animal cells, plant cells, or enzymes, and through technologies such as genetic engineering, cell engineering, and fermentation engineering, to regulate metabolic pathways or catalyze specific biochemical reactions within the organism. Its core is utilizing the organism's own synthetic capabilities to efficiently produce various bioproducts such as vaccines, monoclonal antibodies, recombinant protein drugs, biological enzymes, probiotic preparations, and plant secondary metabolites. Filtration devices used in bioproduct synthesis are used in the production of bioproducts such as vaccines, recombinant proteins, and antibodies to separate impurities from raw materials / products and achieve purity enhancement, while avoiding damage to bioactive substances.

[0003] In the current technology, most filtration devices in the filtration stage of bioproduct synthesis still use a single-layer filter membrane design. Because bioproducts have extremely high purity requirements, they need to meet pharmaceutical-grade standards of sterility, low impurities, or even no residue. A single filtration using a single-layer filter membrane cannot fully retain impurities of different particle sizes (such as cell debris, large molecular protein precipitates, microorganisms, etc.). Multiple filtration processes must be repeated to achieve the target purity, which prolongs the overall filtration time and significantly reduces filtration efficiency. Utility Model Content

[0004] The purpose of this invention is to provide a filtration device for the synthesis of biological products, in order to solve the problem mentioned in the background art that most devices in the filtration process of biological product synthesis still use a single-layer filter membrane. However, biological products need to achieve sterility, low impurities, and pharmaceutical-grade high purity. A single-layer filter membrane cannot fully retain impurities of different particle sizes in a single filtration, so multiple filtrations are required, which prolongs the overall time and reduces the filtration efficiency.

[0005] To achieve the above objectives, this utility model provides the following technical solution: a filtration device for bioproduct synthesis, comprising a filter frame, an inlet fixedly connected to one end of the filter frame, an outlet fixedly connected to the other end of the filter frame, a flow guiding component installed inside the filter frame, a fixing strip fixed to the inner wall of the filter frame, an installation frame installed on the filter frame, a filter membrane body fixedly connected to the installation frame, an installation component installed on the filter frame, and an elastic component installed on the installation component. The installation frame is detachably installed on the fixing strip, which is used to limit the installation frame during installation. The flow guiding component is used to guide and transport the bioproduct between the filter membrane bodies. The installation component is used to install or remove the five sets of installation frames and filter membrane bodies individually.

[0006] Based on the preferred embodiment of this technical solution, five sets of mounting frames and filter membrane bodies are provided, and the five sets of mounting frames and filter membrane bodies are staggered in a stepped manner from top to bottom inside the filter frame.

[0007] Based on the preferred embodiment of this technical solution, the five filter membrane bodies have different pore sizes, and the pore sizes are set from top to bottom as 0.45μm, 0.22μm, 0.1μm, 50nm, and 10nm. The five filter membrane bodies with different pore sizes are used for multi-stage filtration of biological products.

[0008] Based on the preferred embodiment of this technical solution, the flow guiding component includes a flow guiding plate fixedly connected inside the filter frame, an L-shaped strip fixedly connected to one end of the flow guiding plate, an arc surface opened at the other end of the flow guiding plate, and a protrusion fixedly connected to the surface of the flow guiding plate. The L-shaped strip is set on the mounting frame and is used to limit the mounting frame when it is installed. The protrusion is used to increase the turbulence effect of the biological product.

[0009] In the preferred embodiment of this technical solution, the bump is set as a semi-circle. The bump is used to generate micro-vortices and disrupt the concentration polarization layer. At the same time, the semi-circular design reduces fluid resistance.

[0010] Based on the preferred embodiment of this technical solution, the installation components include a sealing airbag fixedly connected inside the filter frame, a mounting plate fixedly connected to one end of the mounting frame, a sealing ring fixedly connected to the mounting frame near the mounting plate, and a square frame fixedly connected to the filter frame. A locking block is slidably connected to the square frame. The sealing airbag is in contact with the other end of the mounting frame, the mounting plate is in contact with the filter frame, the sealing ring is in contact with the filter frame, and the locking block is engaged with the mounting plate. An elastic component is used to provide elasticity to the locking block, and the sealing airbag is used to provide elasticity to the mounting frame after installation, thereby increasing the installation stability of the mounting frame.

[0011] In this preferred embodiment of the technical solution, one end of the card block is set as an arc shape and the other end is set as a straight plate shape. The mounting frame and the mounting plate first contact the arc end of the card block, and the mounting plate has a slot at the corresponding position of the card block. The card block is engaged in the slot of the mounting plate, and the straight plate end is used to abut against the card block when it is engaged in the slot of the mounting plate.

[0012] In a preferred embodiment of this technical solution, the elastic component includes a light rod slidably connected to the square frame, a compression spring fixedly connected between the locking block and the square frame, and a lever fixedly connected to one end of the light rod. The other end of the light rod is fixedly connected to the locking block, and the lever is used to move the light rod.

[0013] Compared with the prior art, the beneficial effects of this utility model are: 1. Five sets of mounting frames and filter membrane bodies are staggered in a stepped manner from top to bottom inside the filter frame. The filter membrane body has filter pores set from top to bottom as 0.45μm, 0.22μm, 0.1μm, 50nm, and 10nm. With the help of the flow guiding component, the biological products are precisely guided and delivered between the filter membrane bodies. Multi-stage filtration can be completed in one go without repeated operations. This effectively simplifies the filtration process, significantly improves filtration efficiency and maintenance convenience, and ensures the continuity and purity of biological product filtration.

[0014] 2. The flow guide plate in the flow guide assembly provides a clear flow path for the biological products, avoiding uneven filtration caused by disordered flow of the biological products in the filter frame. The arc surface at the other end of the flow guide plate can reduce the resistance of the biological products during flow, preventing the biological products from stagnating and deteriorating due to poor flow. The turbulence effect increased by the protrusions can ensure that the biological products are in full contact with the surface of the filter membrane, avoiding the local accumulation of impurities on the filter membrane surface and ensuring the stable filtration flux of the filter membrane.

[0015] 3. Through the sealing airbag in the mounting assembly, elastic support can be applied to the other end of the mounting frame after installation. The sealing ring can fill the gap between the mounting frame and the filter frame to prevent biological products from leaking out of the gap during filtration, ensuring the airtightness of the filtration environment and avoiding external contamination. The snap-fit ​​between the clip and the mounting plate, combined with the elasticity provided by the elastic component, can quickly fix the mounting frame without the need for complex connectors such as bolts, simplifying the installation steps while ensuring a firm snap-fit ​​and reducing disassembly and maintenance time. Attached Figure Description

[0016] Figure 1 This is a schematic diagram of one embodiment of a filtration device for bioproduct synthesis according to the present invention; Figure 2 This is a schematic diagram of the flow guiding component structure of this utility model; Figure 3 This is a schematic diagram of the filter membrane body structure of this utility model; Figure 4 This is a schematic diagram of the protrusion structure of this utility model; Figure 5 This is a schematic diagram of the installation component structure of this utility model; Figure 6 This is a schematic diagram of the elastic component structure of this utility model.

[0017] In the diagram: 1. Filter frame; 21. Fixing strip; 22. Mounting frame; 23. Filter membrane body; 31. Guide plate; 32. L-shaped strip; 33. Protrusion; 34. Arc surface; 41. Mounting plate; 42. Sealing ring; 43. Square frame; 44. Sealing airbag; 45. Smooth rod; 46. Locking block; 47. Compression spring; 48. Pulley; 5. Inlet; 6. Outlet. Detailed Implementation

[0018] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0019] Please see Figure 1-6 This utility model provides an embodiment of a filtration device for bioproduct synthesis, comprising a filter frame 1, an inlet 5 fixedly connected to one end of the filter frame 1, an outlet 6 fixedly connected to the other end of the filter frame 1, a flow guiding component installed inside the filter frame 1, a fixing strip 21 fixed to the inner wall of the filter frame 1, a mounting frame 22 installed on the filter frame 1, a filter membrane body 23 fixedly connected to the mounting frame 22, a mounting assembly installed on the filter frame 1, and an elastic component installed on the mounting assembly. The mounting frame 22 is detachably mounted on the fixing strip 21, which limits its position during installation. The flow guiding component guides and transports the bioproduct between the filter membrane bodies 23. This device is used to individually install or remove the five sets of mounting frames 22 and filter membrane bodies 23. Through the coordinated arrangement of filter frame 1, inlet 5, outlet 6, flow guiding component, fixing strip 21, mounting frame 22, filter membrane body 23, mounting component, and elastic component, the fixing strip 21 ensures the accurate positioning of the mounting frame 22 during installation, preventing the filter membrane body 23 from shifting and affecting the filtration effect. The flow guiding component also guides the biological products to flow orderly between the filter membrane bodies 23, preventing biological product retention. At the same time, the detachable design of the mounting frame 22 and the individual installation and removal function of the mounting component for the five sets of filter membrane bodies 23 eliminate the need for complete disassembly of the device during subsequent maintenance. Damaged filter membranes can be replaced selectively, greatly reducing maintenance difficulty and ensuring long-term stable operation of the device.

[0020] Please see Figure 2-3 A further solution based on this embodiment is as follows: five sets of mounting frames 22 and filter membrane bodies 23 are provided. The five sets of mounting frames 22 and filter membrane bodies 23 are staggered in a stepped manner from top to bottom inside the filter frame 1. Through the staggered staggered arrangement of the five sets of mounting frames 22 and filter membrane bodies 23 from top to bottom, the biological products can flow through each set of filter membrane bodies 23 sequentially along the smooth path formed by the staggered arrangement after entering from the inlet 5. This avoids the problem of obstructed flow of biological products caused by the concentrated overlap of multiple sets of filter membranes. At the same time, the staggered design can also increase the contact area between the biological products and the filter membrane bodies 23, reduce the situation of excessive local filtration pressure, prevent the filter membrane bodies 23 from being damaged due to uneven force, extend the service life of the filter membrane, and make the filtration process more continuous, avoiding the interruption of operation due to path blockage.

[0021] Please see Figure 2A further embodiment of this solution is as follows: the five filter membrane bodies 23 have different pore sizes, and the pore sizes are set sequentially from top to bottom as 0.45μm, 0.22μm, 0.1μm, 50nm, and 10nm. The five filter membrane bodies 23 with different pore sizes are used for multi-stage filtration of biological products. Through the five filter membrane bodies 23 with progressively decreasing pore sizes, multi-stage filtration of biological products from coarse to fine filtration can be achieved: first, larger particulate impurities are intercepted by the 0.45μm filter membrane, then fine impurities and microorganisms are gradually removed by the 0.22μm and 0.1μm filter membranes, and finally, large molecular impurities are intercepted by the 50nm and 10nm filter membranes, ensuring that the purity of the final biological product meets the standards. This graded filtration eliminates the need for multiple filter membrane replacements or repeated filtration, simplifies the operation process, avoids the loss of target products caused by multiple transfers of biological products, and improves the recovery rate of biological products.

[0022] Please see Figure 2-4 A further solution based on this embodiment is as follows: the flow guiding assembly includes a flow guiding plate 31 fixedly connected inside the filter frame 1, an L-shaped strip 32 fixedly connected to one end of the flow guiding plate 31, an arc surface 34 formed at the other end of the flow guiding plate 31, and a protrusion 33 fixedly connected to the surface of the flow guiding plate 31. The L-shaped strip 32 is disposed on the mounting frame 22 and is used to limit the mounting frame 22 when it is installed. The protrusion 33 is used to increase the turbulence effect of the biological product. Through the flow guiding plate 31 in the flow guiding assembly, a clear flow path can be provided for the biological product, avoiding the biological product from being... Uneven filtration caused by disordered flow within the filter frame 1; L-shaped strip 32 can further assist the fixing strip 21 in limiting the position when installing the mounting frame 22, ensuring the precise positioning of the mounting frame 22 and the filter membrane body 23, reducing filter membrane misalignment and leakage problems caused by installation deviation; the arc surface 34 at the other end of the guide plate 31 can reduce the resistance when the biological product flows, preventing the biological product from stagnating and deteriorating due to poor flow; the turbulence effect increased by the protrusion 33 can allow the biological product to fully contact the surface of the filter membrane body 23, avoiding local accumulation of impurities on the filter membrane surface, and ensuring stable filtration flux of the filter membrane.

[0023] The flow guiding component can also adopt other structures in the existing technology, such as an inclined surface, which replaces the arc surface 34. The advantages are: the planar guiding structure on the inclined surface can guide the biological products to flow smoothly along the preset inclined direction, reduce the stagnation in the flow path, and improve the flow guiding efficiency; at the same time, the inclined surface has no curved dead corners, and can be directly rinsed during cleaning to avoid impurity residue, which is more in line with the cleanliness requirements of biological product filtration.

[0024] Please see Figure 4A further solution based on this embodiment is as follows: the protrusion 33 is set as a semi-circle. The protrusion 33 is used to generate micro-vortices and destroy the concentration polarization layer. At the same time, the semi-circular design reduces fluid resistance. By setting the protrusion 33 as a semi-circle, its rounded surface can guide the biological product to generate micro-vortices while avoiding sharp structures from causing shear damage to the active ingredients in the biological product, thus protecting the activity of the biological product. The micro-vortices can effectively destroy the concentration polarization layer on the surface of the filter membrane, preventing impurities from agglomerating on the filter membrane surface due to excessive concentration, and ensuring that the filter membrane always maintains a high filtration efficiency. In addition, compared with square, triangular and other shapes, the semi-circular design can significantly reduce the frictional resistance when the biological product flows, reduce the energy consumption required to transport the biological product, and avoid the problem of uneven flow speed of the biological product caused by excessive resistance.

[0025] Please see Figure 5-6 A further solution based on this embodiment is as follows: the installation assembly includes a sealing airbag 44 fixedly connected inside the filter frame 1, a mounting plate 41 fixedly connected to one end of the mounting frame 22, a sealing ring 42 fixedly connected to the mounting frame 22 near the mounting plate 41, and a square frame 43 fixedly connected to the filter frame 1. A locking block 46 is slidably connected to the square frame 43. The sealing airbag 44 is in contact with the other end of the mounting frame 22, the mounting plate 41 is in contact with the filter frame 1, the sealing ring 42 is in contact with the filter frame 1, and the locking block 46 is engaged with the mounting plate 41. An elastic component is used to provide elasticity to the locking block 46, and the sealing airbag 44 is used to provide elasticity to the mounting frame 22 after installation, thereby increasing the installation stability of the mounting frame 22. After the mounting frame 22 is installed, it can apply elastic support to its other end, buffering the impact of device vibration on the mounting frame 22 during filtration and preventing filter membrane displacement caused by loosening of the mounting frame 22; the contact fit between the mounting plate 41 and the filter frame 1 can further limit the lateral displacement of the mounting frame 22 and improve the overall stability of the mounting frame 22; the sealing ring 42 can fill the gap between the mounting frame 22 and the filter frame 1 to prevent biological products from leaking from the gap during filtration, ensuring the airtightness of the filtration environment and avoiding external contamination; the snap-fit ​​fit between the locking block 46 and the mounting plate 41, combined with the elasticity provided by the elastic component, can quickly fix the mounting frame 22 without the need for complex connecting parts such as bolts, simplifying the installation steps, while ensuring a firm snap-fit ​​and reducing disassembly and maintenance time.

[0026] Please see Figure 6A further solution based on this embodiment is as follows: one end of the locking block 46 is set in an arc shape, and the other end is set in a straight plate shape. Both the mounting frame 22 and the mounting plate 41 first contact the arc end of the locking block 46, and the mounting plate 41 has a corresponding slot on the locking block 46. The locking block 46 is engaged with the slot of the mounting plate 41. The straight plate end is used to abut against the locking block 46 when it is engaged with the slot of the mounting plate 41. By setting one end of the locking block 46 in an arc shape, the arc end can guide the mounting plate 41 to slide smoothly when installing the mounting frame 22 and the mounting plate 41, avoiding jamming or sticking during installation, reducing the difficulty of installation operation, and allowing operators to operate without... Preliminary positioning can be completed with precise alignment; the slot on the mounting plate 41 and the locking block 46 fit precisely to ensure that the locking block 46 can be stably locked onto the mounting plate 41, preventing the mounting frame 22 from falling off during use; the straight plate design at the other end of the locking block 46 can form abutment with the mounting plate 41 after the locking block 46 is locked into the slot, and the sealing airbag 44 can apply elastic support to the other end after the mounting frame 22 is installed, further restricting the movement of the locking block 46, improving the stability of the locking, and preventing the locking block 46 from falling out of the slot due to device vibration, ensuring the stable installation state of the mounting frame 22 and the filter membrane body 23, and ensuring the normal operation of filtration.

[0027] Please see Figure 6 A further solution based on this embodiment is as follows: the elastic component includes a light rod 45 slidably connected to the square frame 43, a compression spring 47 fixedly connected between the locking block 46 and the square frame 43, and a lever 48 fixedly connected to one end of the light rod 45. The other end of the light rod 45 is fixedly connected to the locking block 46. The lever 48 is used to move the light rod 45. Through the compression spring 47 in the elastic component, an elastic force can be continuously applied to the locking block 46 to ensure that the locking block 46 is always tightly locked in the slot of the mounting plate 41, and to prevent the locking block 46 from being damaged due to long-term use. The installation frame 22 is improved by preventing loosening; the sliding connection between the smooth rod 45 and the square frame 43 provides guidance for the movement of the locking block 46, preventing the locking block 46 from shifting under force and ensuring that the locking block 46 can accurately enter or exit the slot; the setting of the toggle block 48 allows the operator to move the smooth rod 45 by toggling the toggle block 48, thereby controlling the locking block 46 to disengage from the slot, so that the installation frame 22 can be disassembled without the aid of tools, simplifying the maintenance operation process, saving disassembly time, allowing the device to quickly resume filtration operation, and reducing downtime losses.

[0028] The elastic component can also adopt other structures in the existing technology, such as a square rod instead of the bare rod 45. The advantages are: the square rod and the square hole of the square frame 43 form a surface contact fit, which can completely limit the rotation of the rod body and avoid the offset of the locking block 46 and the misalignment of the locking slot; its fit gap is smaller and the sliding guide is more stable, which can reduce the jamming and skew of the locking block 46; at the same time, the square rod has no risk of rotation, and the connection with the locking block 46 and the lever block 48 is more firm and not easy to loosen. The force transmission is also more uniform, which can avoid local deformation and further ensure the precise fixation of the locking block 46 to the mounting frame 22 and the stable use of the elastic component.

[0029] Working principle: First, the fixing strip 21 on the inner wall of the filter frame 1 cooperates with the L-shaped strip 32 of the flow guiding component to double limit the five sets of mounting frames 22, so that the mounting frames 22 can be detachably installed in the filter frame 1; at this time, the locking block 46 of the mounting component is precisely locked in the mounting plate 41 slot of the mounting frame 22 under the continuous elastic force of the elastic component compression spring 47. At the same time, the sealing airbag 44 of the mounting component applies elastic support force to the other end of the mounting frame 22, and the sealing ring 42 fills the gap between the mounting frame 22 and the filter frame 1, ensuring that the mounting frame 22 and the filter membrane body 23 fixed on it are stable and sealed. During filtration, the biological sample enters through the inlet 5 at one end of the filter frame 1 and flows along a preset path under the guidance of the guide plate 31 of the flow guiding component. The arc surface 34 at the other end of the guide plate 31 greatly reduces the flow resistance of the biological sample, and the semi-circular protrusions 33 on its surface generate micro-vortices, which can both destroy the concentration polarization layer on the surface of the filter membrane body 23 and prevent impurities from accumulating, and protect the active ingredients of the biological sample from shear damage. Subsequently, the biological sample flows along the five sets of filter membrane bodies 23 that are staggered in a stepped manner, and passes through filter membranes with filtration pores of 0.45μm, 0.22μm, 0.1μm, 50nm, and 10nm in sequence, gradually intercepting various impurities from large particles to small molecules, realizing one-time multi-stage filtration from coarse filtration to fine filtration. Finally, the biological products that meet the purity requirements are discharged from the outlet 6 at the other end of the filter frame 1. When the filter membrane needs to be replaced, simply move the lever 48 of the elastic component to move the light rod 45, so that the locking block 46 is disengaged from the mounting plate 41 slot, and the corresponding mounting frame 22 can be disassembled separately to replace the filter membrane body 23. No overall disassembly device is required, ensuring the continuity of filtration operations and the convenience of maintenance.

[0030] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A filtration device for bioproduct synthesis, comprising a filter frame (1), characterized in that: It also includes an inlet (5) fixedly connected to one end of the filter frame (1), an outlet (6) fixedly connected to the other end of the filter frame (1), a flow guiding component installed inside the filter frame (1), a fixing strip (21) fixed to the inner wall of the filter frame (1), an installation frame (22) installed on the filter frame (1), a filter membrane body (23) fixedly connected to the installation frame (22), an installation component installed on the filter frame (1), and an elastic component installed on the installation component. The installation frame (22) is detachably installed on the fixing strip (21). The fixing strip (21) is used to limit the installation frame (22) when it is installed. The flow guiding component is used to guide and transport biological products between the filter membrane bodies (23). The installation component is used to install or remove the five sets of installation frames (22) and filter membrane bodies (23) individually.

2. The filtration device for bioproduct synthesis according to claim 1, characterized in that: The mounting frame (22) and the filter membrane body (23) are each provided with five sets. The five sets of mounting frames (22) and filter membrane bodies (23) are staggered in a stepped manner from top to bottom inside the filter frame (1).

3. A filtration device for bioproduct synthesis according to claim 1, characterized in that: The five filter membrane bodies (23) have different pore sizes, and the pore sizes are set from top to bottom as 0.45μm, 0.22μm, 0.1μm, 50nm and 10nm respectively. The five filter membrane bodies (23) with different pore sizes are used for multi-stage filtration of biological products.

4. A filtration device for bioproduct synthesis according to claim 1, characterized in that: The flow guiding assembly includes a flow guiding plate (31) fixedly connected inside the filter frame (1), an L-shaped strip (32) fixedly connected to one end of the flow guiding plate (31), an arc surface (34) opened at the other end of the flow guiding plate (31), and a protrusion (33) fixedly connected to the surface of the flow guiding plate (31). The L-shaped strip (32) is set on the mounting frame (22). The L-shaped strip (32) is used to limit the mounting frame (22) when it is installed. The protrusion (33) is used to increase the turbulence effect of the biological product.

5. A filtration device for bioproduct synthesis according to claim 4, characterized in that: The bump (33) is set as a semi-circle. The bump (33) is used to generate micro vortices and destroy the concentration polarization layer. At the same time, the semi-circular design reduces fluid resistance.

6. A filtration device for bioproduct synthesis according to claim 1, characterized in that: The mounting components include a sealing airbag (44) fixedly connected inside the filter frame (1), a mounting plate (41) fixedly connected to one end of the mounting frame (22), a sealing ring (42) fixedly connected to the mounting frame (22) near the mounting plate (41), and a square frame (43) fixedly connected to the filter frame (1). A locking block (46) is slidably connected to the square frame (43). The sealing airbag (44) is in contact with the other end of the mounting frame (22), the mounting plate (41) is in contact with the filter frame (1), the sealing ring (42) is in contact with the filter frame (1), and the locking block (46) is locked onto the mounting plate (41). An elastic component is used to provide elasticity to the locking block (46), and the sealing airbag (44) is used to provide elasticity to the mounting frame (22) after installation, thereby increasing the installation stability of the mounting frame (22).

7. A filtration device for bioproduct synthesis according to claim 6, characterized in that: One end of the card block (46) is set as an arc shape, and the other end is set as a straight plate shape. The mounting frame (22) and the mounting plate (41) first contact the arc end of the card block (46), and the mounting plate (41) has a card slot at the corresponding position of the card block (46). The card block (46) is engaged in the card slot of the mounting plate (41), and the straight plate end is used to abut when the card block (46) is engaged in the card slot of the mounting plate (41).

8. A filtration device for bioproduct synthesis according to claim 1, characterized in that: The elastic component includes a light rod (45) slidably connected to the square frame (43), a compression spring (47) fixedly connected between the locking block (46) and the square frame (43), and a toggle block (48) fixedly connected to one end of the light rod (45). The other end of the light rod (45) is fixedly connected to the locking block (46), and the toggle block (48) is used to move the light rod (45).

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