A temperature-controllable vaccine development test observation box

CN224793548UActive Publication Date: 2026-09-25JIANGSU LEVIESTER BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202522309677.X
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-10-31
Publication Date
2026-09-25
Estimated Expiration
2035-10-31

AI Technical Summary

Technical Problem

[0003]现有技术中的疫苗试验观察箱多采用整体式温控结构,即箱体内腔温度保持均一,同一时间段内仅能为所有试验样本提供单一温度环境

Benefits of technology

[0015](1)通过若干组分区隔板将箱体分隔为多个独立试验腔,且每个试验腔配置一套含半导体制冷片、加热管的独立温控组件,可同时实现不同温度的控制,无需多台设备即可完成疫苗样本的多温对比试验,解决单设备单温的核心局限;

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field of vaccine research and development test equipment, concretely is a kind of partition temperature control's test observation box for vaccine research and development, including box, several groups of partitioning baffle are installed in the box, several groups of the partitioning baffle are separated multiple independent test cavities to box, each the test cavity is installed with support plate, and each independent test cavity is correspondingly configured with a set of temperature control assembly, the temperature control assembly includes semiconductor refrigerating sheet, heat conducting plate, cooling fan, heating pipe and temperature controller, several groups of the semiconductor refrigerating sheet and several groups of heating pipe are respectively embedded in the side wall of each independent test cavity, the box is separated into multiple independent test cavities by several groups of partitioning baffle, and each test cavity is configured with a set of independent temperature control assembly containing semiconductor refrigerating sheet, heating pipe, the control of different temperature can be realized simultaneously, the multi-temperature comparison test of vaccine sample can be completed without multiple equipment, solve the core limitation of single equipment single temperature.
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Description

Technical Field

[0001] This utility model relates to the field of vaccine research and development testing equipment technology, specifically a test observation box for vaccine research and development with adjustable temperature in different zones. Background Technology

[0002] During vaccine development, it is necessary to conduct long-term observation tests on the stability and activity changes of vaccine samples under different temperature environments. This requires the test observation chamber to be able to accurately control the internal temperature and simulate different storage conditions.

[0003] Existing vaccine trial observation chambers mostly employ an integrated temperature control structure, meaning the internal temperature of the chamber remains uniform, providing only a single temperature environment for all test samples within a given time period. However, vaccine development trials often require simultaneous comparison of the effects of different temperatures on vaccine samples. This necessitates the preparation of multiple observation chambers of different specifications for separate testing, increasing equipment procurement costs and laboratory space requirements. Furthermore, the varying temperature control accuracy of different devices leads to a lack of accurate cross-sectional comparisons of experimental data. Therefore, this invention proposes a zoned temperature-adjustable vaccine development observation chamber to address these issues. Utility Model Content

[0004] The purpose of this invention is to provide a vaccine research and development experimental observation box with adjustable temperature in different zones, so as to solve the problem of single-temperature environment testing mentioned in the background art.

[0005] To achieve the above objectives, this utility model provides the following technical solution: a zoned temperature-adjustable experimental observation box for vaccine research and development, comprising a box body;

[0006] The chamber is equipped with several partitions, which divide the chamber into multiple independent test chambers. Each test chamber is equipped with a support plate, and each independent test chamber is equipped with a temperature control assembly, which includes a thermoelectric cooler, a heat-conducting plate, a cooling fan, a heating element, and a temperature controller. The thermoelectric cooler and the heating element are embedded in the side wall of each independent test chamber. The cooling fan is installed on the top of the chamber and connected to the heat-conducting plate, which is connected to the thermoelectric cooler.

[0007] Preferably, the temperature controller is fixed to the side wall of the box and electrically connected to the semiconductor cooling chip and the heating tube respectively. The temperature controller is equipped with a temperature display screen and adjustment buttons.

[0008] Preferably, each of the independent test chambers has a support plate fixedly provided on both sides of its side walls, and each pair of opposite support plates together support a set of support plates, with both the upper and lower sets of support plates having an open structure.

[0009] Preferably, a flow divider is fixedly installed on the upper cavity wall of each independent test chamber. A spacer protrusion is provided in the middle of the flow divider along the vertical direction. The spacer protrusion defines the top of the independent test chamber as two symmetrically distributed airflow chambers. A through hole is provided on the flow divider, and the spacer protrusion forms a half-segment with respect to the through hole.

[0010] Preferably, one of the through holes is directly opposite to and connected to the plate area of ​​the upper support plate in the vertical direction, and the bottom port of the other through hole is sealed to one end of the guide pipe. The other end of the guide pipe is connected to a guide plate. The bottom of the guide plate has several exhaust holes, and the guide plate is fixedly assembled between two adjacent sets of support plates.

[0011] Preferably, the side wall of the chamber is equipped with several sets of temperature sensors, each set of temperature sensors is embedded inside each independent test chamber, and the side wall of the chamber is also equipped with a data logger. The temperature sensors are electrically connected to the data logger through wires, and the data logger is equipped with a USB data export interface.

[0012] Preferably, a rechargeable lithium battery pack is fixedly installed on one side of the inner wall of the top of the housing, and the lithium battery pack is electrically connected to the cooling fan and the heating tube respectively through wires.

[0013] Preferably, each of the independent test chambers has a partition door hinged to its sidewall.

[0014] Compared with the prior art, the beneficial effects of this utility model are:

[0015] (1) The chamber is divided into multiple independent test chambers by several component partitions, and each test chamber is equipped with an independent temperature control component containing a semiconductor cooling chip and a heating tube, which can simultaneously control different temperatures. The multi-temperature comparison test of vaccine samples can be completed without multiple devices, thus solving the core limitation of single device single temperature.

[0016] (2) Temperature control is achieved through the combination structure of the split plate, the spacer plate, the guide tube and the guide plate. The spacer plate divides the top of the test chamber into two airflow chambers. The through holes on the split plate form two independent airflow paths. One through hole is directly connected to the upper support plate, so that the cold air generated by the semiconductor cooling chip or the hot air generated by the heating tube directly acts on the upper support plate. The other through hole is connected to the guide plate located between the upper and lower support plates through the guide tube. The cold air / hot air is transported to the lower support plate through the exhaust hole at the bottom of the guide plate. This design breaks the limitation of the heat source acting nearby and reduces the temperature gradient between the upper and lower zones. Attached Figure Description

[0017] Figure 1 This is a schematic diagram of the overall structure of this utility model.

[0018] Figure 2 This is a schematic diagram of the internal structure of the box of this utility model.

[0019] Figure 3 This is a schematic diagram of the diverter plate installation structure of this utility model.

[0020] Figure 4 This is a schematic diagram of the guide plate installation structure of this utility model.

[0021] In the diagram: 1. Housing; 2. Partition plate; 21. Support plate; 3. Support plate; 4. Semiconductor cooling chip; 5. Heat conduction plate; 6. Cooling fan; 7. Heating tube; 8. Lithium battery pack; 9. Diverter plate; 91. Spacer protrusion; 92. Through hole; 10. Guide pipe; 101. Guide plate; 11. Partition door; 12. Temperature sensor; 13. Temperature controller; 14. Data logger. Detailed Implementation

[0022] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0023] Please see Figures 1 to 4 This utility model provides a technical solution: a zoned temperature-adjustable experimental observation box for vaccine research and development, including a box body 1, in which several partition plates 2 are installed, dividing the box body 1 into multiple independent test chambers, each test chamber is equipped with a support plate 3, and each independent test chamber is equipped with a temperature control component, which includes a semiconductor cooling chip 4, a heat-conducting plate 5, a cooling fan 6, a heating tube 7, and a temperature controller 13. Several sets of semiconductor cooling chips 4 and several sets of heating tubes 7 are respectively embedded in the side wall of each independent test chamber, and the cooling fan 6 is installed on the top of the box body 1 and connected to the heat-conducting plate 5, and the heat-conducting plate 5 is connected to the semiconductor cooling chip 4.

[0024] The chamber 1 is divided into multiple independent test chambers by several partitions 2, and each independent test chamber is equipped with a temperature control component containing a semiconductor cooling chip 4 and a heating tube 7. This allows for the simultaneous provision of differentiated temperature environments for vaccine samples in different test chambers, eliminating the need to purchase multiple traditional single-temperature observation chambers and significantly reducing equipment procurement costs. At the same time, the integrated chamber 1 structure only requires the laboratory space of a single device, solving the problem of large space occupation by traditional multiple devices and improving the flexibility of laboratory layout. In addition, each set of temperature control components operates independently and can adjust the temperature of the corresponding test chamber individually according to the test requirements, avoiding mutual interference between different temperature zones and ensuring the independence of the test environment for multiple sets of vaccine samples.

[0025] Please see Figure 2 The thermostat 13 is fixed to the side wall of the housing 1 and is electrically connected to the semiconductor cooling chip 4 and the heating tube 7 respectively. The thermostat 13 is equipped with a temperature display screen and adjustment buttons.

[0026] Please see Figure 2 Each independent test chamber has a support plate 21 fixedly installed on both sides of its side walls. Each pair of support plates 21 together support a set of support plates 3. Both the upper and lower sets of support plates 3 have open structures.

[0027] The support plates 21, which are fixed to each side wall of each independent test chamber, can provide symmetrical and stable support for the support plate 3, preventing the support plate 3 from tilting or falling off after placing the vaccine sample. At the same time, each set of support plates 21 supports one set of support plates 3, and the number of layers of support plates 3 can be flexibly set according to the height of the test chamber and the sample specifications, so as to realize the layered placement of samples in the limited test chamber space and improve the space utilization rate inside the box 1.

[0028] Please see Figures 3 to 4 Each independent test chamber has a flow divider 9 fixedly installed on the upper cavity wall. The middle part of the flow divider 9 has a vertically protruding partition plate 91. The partition plate 91 defines the top of the independent test chamber as two symmetrically distributed airflow chambers. The flow divider 9 has a through hole 92. The partition plate 91 forms a half-segment with the through hole 92. One side of the through hole 92 is directly opposite to the plate area of ​​the upper support plate 3 and maintains communication. The bottom port of the other side of the through hole 92 is sealed to one end of the guide pipe 10. The other end of the guide pipe 10 is connected to the guide plate 101. The bottom of the guide plate 101 has several exhaust holes. The guide plate 101 is fixedly assembled between two adjacent sets of support plates 3.

[0029] Temperature control is achieved through a combination of a flow divider 9, a spacer 91, a guide tube 10, and a guide plate 101. The spacer 91 divides the top of the test chamber into two airflow chambers. The through holes 92 on the flow divider 9 form two independent airflow paths. One through hole 92 is directly connected to the upper support plate 3, allowing the cold air generated by the semiconductor cooling chip 4 or the hot air generated by the heating tube 7 to directly act on the upper support plate 3. The other through hole 92 is connected to the guide plate 101 located between the upper and lower support plates 3 through the guide tube 10. The cold / hot air is delivered to the lower support plate 3 through the exhaust hole at the bottom of the guide plate 101. This design breaks the limitation of the heat source acting nearby and reduces the temperature gradient between the upper and lower zones.

[0030] Please see Figure 2Several sets of temperature sensors 12 are installed on the side wall of the chamber 1. Each set of temperature sensors 12 is embedded inside each independent test chamber. A data logger 14 is also installed on the side wall of the chamber 1. The temperature sensors 12 are electrically connected to the data logger 14 through wires. The data logger 14 is equipped with a USB data export interface.

[0031] Several sets of temperature sensors 12 installed on the side wall of the chamber 1 are embedded in each independent test chamber. They can directly collect real-time temperature data of each test chamber, ensuring that researchers can keep track of the real temperature environment of the vaccine samples in real time. The temperature sensors 12 are electrically connected to the data logger 14 on the side wall of the chamber 1 through wires, which can automatically transmit the real-time collected temperature data to the data logger 14 for storage. Researchers do not need to record the data manually at regular intervals, avoiding problems such as omissions, errors, and data tampering that are prone to occur with manual recording.

[0032] Please see Figure 2 A rechargeable lithium battery pack 8 is fixedly installed on one side of the inner wall of the top of the housing 1. The lithium battery pack 8 is electrically connected to the cooling fan 6 and the heating tube 7 through wires.

[0033] Please see Figure 1 Each independent test chamber has a partition door 11 hinged to its side wall.

[0034] In use, open the partition door 11 of the independent test chamber, place the vaccine samples in layers on the support plate 3 supported by the support plate 21, close the partition door 11, and start the equipment. Set the target temperature of each test chamber through the temperature controller 13 on the side wall of the chamber 1. The temperature controller 13 sends signals to the semiconductor cooling chip 4 or heating tube 7 on the side wall of the corresponding test chamber. When cooling is required, the semiconductor cooling chip 4 works, and the heat generated is conducted through the heat conduction plate 5 to the cooling fan 6 at the top of the chamber 1 for exhaust. When heating is required, the heating tube 7 heats up. The spacer plate 91 of the diversion plate 9 divides the top of the test chamber into two airflow chambers. The cold / hot air generated by the semiconductor cooling chip 4 or heating tube 7 is partly delivered to the upper support plate 3 through the through hole 92 on one side of the diversion plate 9, and the other part is transported to the guide plate 101 between the upper and lower support plates 3 through the guide pipe 10, and then diffused to the lower support plate 3 through the exhaust hole at the bottom of the guide plate 101. Combined with the opening structure of the support plate 3, the temperature in the chamber is made uniform.

[0035] At this time, the temperature sensor 12 collects the temperature of each test chamber in real time, and the data is transmitted to the data logger 14 for storage. It can be exported for analysis via USB interface. The device prioritizes mains power supply and charges the lithium battery pack 8 at the same time. When the power is off, the lithium battery pack 8 automatically supplies power to the cooling fan 6 and heating tube 7 to ensure continuous operation of temperature control and realize synchronous and stable testing in multiple temperature zones.

[0036] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A zoned temperature-controlled experimental observation box for vaccine research and development, comprising a box body (1), characterized in that: The chamber (1) is equipped with several partition plates (2), which divide the chamber (1) into multiple independent test chambers. Each test chamber is equipped with a support plate (3), and each independent test chamber is equipped with a set of temperature control components. The temperature control components include a thermoelectric cooler (4), a heat-conducting plate (5), a cooling fan (6), a heating tube (7), and a temperature controller (13). Several sets of thermoelectric coolers (4) and several sets of heating tubes (7) are embedded in the side wall of each independent test chamber. The cooling fan (6) is installed on the top of the chamber (1) and connected to the heat-conducting plate (5). The heat-conducting plate (5) is connected to the thermoelectric cooler (4).

2. The experimental observation box for vaccine research and development with adjustable temperature in zones according to claim 1, characterized in that: The temperature controller (13) is fixed to the side wall of the box (1) and electrically connected to the semiconductor cooling chip (4) and the heating tube (7) respectively. The temperature controller (13) is equipped with a temperature display screen and adjustment buttons.

3. The experimental observation box for vaccine research and development with adjustable temperature in zones according to claim 1, characterized in that: Each of the independent test chambers has a support plate (21) fixedly installed on both sides of the chamber. Each pair of support plates (21) supports a support plate (3). Both the upper and lower support plates (3) are perforated structures.

4. The experimental observation box for vaccine research and development with adjustable temperature in zones according to claim 3, characterized in that: A flow divider (9) is fixedly installed on the upper cavity wall of each independent test chamber. A spacer plate (91) is provided in the middle of the flow divider (9) along the vertical direction. The spacer plate (91) defines the top of the independent test chamber as two symmetrically distributed airflow chambers. A through hole (92) is provided on the flow divider (9). The spacer plate (91) forms a half-splitting separation with respect to the through hole (92).

5. The experimental observation box for vaccine research and development with adjustable temperature in zones according to claim 4, characterized in that: One of the through holes (92) is directly opposite to and connected to the plate area of ​​the upper support plate (3) in the vertical direction. The bottom port of the other through hole (92) is sealed to one end of the guide pipe (10). The other end of the guide pipe (10) is connected to a guide plate (101). The bottom of the guide plate (101) has several exhaust holes, and the guide plate (101) is fixedly assembled between two sets of support plates (3) arranged adjacent to each other.

6. The experimental observation box for vaccine research and development with adjustable temperature in zones according to claim 1, characterized in that: The side wall of the chamber (1) is equipped with several sets of temperature sensors (12), each set of temperature sensors (12) is embedded in the interior of each independent test chamber. The side wall of the chamber (1) is also equipped with a data logger (14). The temperature sensors (12) are electrically connected to the data logger (14) through wires. The data logger (14) is equipped with a USB data export interface.

7. A zoned temperature-adjustable experimental observation box for vaccine research and development according to claim 6, characterized in that: A rechargeable lithium battery pack (8) is fixedly installed on one side of the inner wall of the top of the box (1). The lithium battery pack (8) is electrically connected to the cooling fan (6) and the heating tube (7) respectively through wires.

8. The experimental observation box for vaccine research and development with adjustable temperature in zones according to claim 4, characterized in that: Each of the independent test chambers is hinged to a partition door (11) on its sidewall.