A heat sealing apparatus for a flexible bioreactor

Abstract

The utility model relates to a kind of heat sealing equipment for flexible bioreactor including rack, first heat sealing mechanism, second heat sealing mechanism and controller;First heat sealing mechanism includes first heat sealing head, first driving part and first heating module, first driving part is installed on rack, first driving part is connected with first heat sealing head, and first heat sealing head is connected with first heating module;Second heat sealing mechanism includes second heat sealing head, second driving part and second heating module, second driving part is installed on rack, second driving part is connected with second heat sealing head, and second heat sealing head is connected with second heating module;First heat sealing head is equipped with first pressure sensor and first temperature sensor;Second heat sealing head is equipped with second pressure sensor and second temperature sensor, and second pressure sensor and second temperature sensor are electrically connected with controller;Each sensor, driving part and heating module are electrically connected with controller.

Description

Technical Field

[0001] This utility model relates to the field of bioreactor equipment technology, and more specifically, to a heat sealing device for a flexible bioreactor. Background Technology

[0002] Flexible bioreactors, with their advantages of light weight, easy installation, and foldable storage, are widely used in biopharmaceuticals, cell culture, and microbial fermentation. Furthermore, flexible bioreactors can be customized to meet the space requirements, stirring methods, or sampling requirements of the application scenario, further expanding their application scope. Their manufacturing process requires two key heat-sealing steps: the first step is to heat-seal the functional connector to the high-barrier composite plastic film; the second step is to heat-seal the plastic film with the connector into a sealed bag.

[0003] Existing heat sealing equipment is mostly designed for conventional flexible packaging. When used for heat sealing of flexible bioreactors, it has the following problems: First, the heat sealing temperature control accuracy is low, which can easily lead to over-heat sealing and film damage, or under-heat sealing and poor sealing. Second, the pressing force cannot be precisely adjusted according to the thickness and material of the flexible film. Excessive pressing force can easily cause film deformation, while insufficient pressing force will affect the heat sealing effect. Utility Model Content

[0004] This invention provides a heat sealing device for flexible bioreactors, aiming to solve the problems of low temperature control accuracy and inaccurate adjustment of pressing force in existing heat sealing devices.

[0005] To achieve the above objectives, the present invention adopts the following technical solution: a heat sealing device for a flexible bioreactor, comprising a frame, a first heat sealing mechanism for heat sealing a joint to a plastic film, a second heat sealing mechanism for heat sealing the plastic film into a sealed bag, and a controller disposed on the frame, wherein the first heat sealing mechanism and the second heat sealing mechanism are sequentially disposed on the frame, and both the first heat sealing mechanism and the second heat sealing mechanism are electrically connected to the controller;

[0006] The first heat-sealing mechanism includes a first heat-sealing head, a first driving component, and a first heating module. The first driving component is fixedly mounted on the frame. The driving end of the first driving component is connected to the first heat-sealing head. The first heat-sealing head is connected to the first heating module. Both the first heating module and the first driving component are electrically connected to the controller.

[0007] The second heat-sealing mechanism includes a second heat-sealing head, a second driving component, and a second heating module. The second driving component is fixedly mounted on the frame. The driving end of the second driving component is connected to the second heat-sealing head. The second heat-sealing head is connected to the second heating module. Both the second heating module and the second driving component are electrically connected to the controller.

[0008] The first heat-sealing head is equipped with a first pressure sensor and a first temperature sensor, both of which are electrically connected to the controller.

[0009] The second heat-sealing head is equipped with a second pressure sensor and a second temperature sensor, both of which are electrically connected to the controller.

[0010] Furthermore, the first heat-sealing head includes an upper heat-sealing head detachably mounted on the driving end of the first driving component and a lower heat-sealing head detachably mounted on the frame. The upper heat-sealing head and the lower heat-sealing head are arranged opposite to each other, and both the upper heat-sealing head and the lower heat-sealing head are connected to the first heating module.

[0011] Furthermore, the second heat-sealing head includes a heat-sealing sheet mounted on the driving end of the second driving component and a heat-sealing block mounted on the frame. The heat-sealing sheet and the heat-sealing block are arranged opposite to each other, and both the heat-sealing sheet and the heat-sealing block are connected to the second heating module.

[0012] Furthermore, both the first driving component and the second driving component are selected as servo cylinders.

[0013] Furthermore, the frame is provided with a movable carrier plate, which is configured corresponding to the lower heat sealing head.

[0014] Furthermore, the frame is provided with a movable stop, which is configured corresponding to the second heat-sealing head.

[0015] Furthermore, the frame is provided with adjusting bolts, which are located on both sides of the lower heat-sealing head. The carrier plate has through holes, through which the carrier plate passes onto the adjusting bolts. The adjusting bolts are provided with adjusting nuts, which are threadedly connected to the adjusting bolts. The upper end face of the adjusting nut abuts against the lower end face of the carrier plate.

[0016] Furthermore, the frame is provided with a cutting mechanism, which is located between the second heat-sealing head and the stop block.

[0017] Furthermore, the cutting mechanism includes a first blade, a second blade, and a rotary cylinder. Both the first blade and the second blade are provided with cutting edges. Both the first blade and the rotary cylinder are fixedly mounted on the frame. The second blade is located above the first blade. The cutting edges of the first blade and the second blade are arranged opposite to each other. The rotating shaft of the rotary cylinder is connected to the second blade. The rotary cylinder can drive the second blade to rotate toward the first blade. The rotary cylinder is electrically connected to the controller.

[0018] Furthermore, the frame is provided with a sliding groove, the bottom of the stop is provided with a slider, the slider is inserted into the sliding groove, and the stop is slidably connected to the sliding groove.

[0019] Compared with the prior art, the beneficial effects of this utility model are as follows: The first heat-sealing mechanism can heat-seal and fix the plastic joint to the plastic film; the second heat-sealing mechanism can heat-seal the plastic film with the plastic joint after heat sealing into a sealed bag; the controller can control the operation of the first and second heat-sealing mechanisms; the first pressure sensor can detect the pressure value of the first heat-sealing head and feed the pressure value data back to the controller; the controller can control the range of motion of the driving end of the first driving component according to the pressure value data transmitted by the first pressure sensor, keeping it within a suitable range. This avoids excessive pressure of the first heat-sealing head causing deformation of the plastic film and plastic joint, or insufficient pressure affecting the heat-sealing effect; the first temperature sensor can detect the temperature of the first heat-sealing head and feed the temperature value data back to the controller; the controller can control the temperature of the first heating module according to the temperature value transmitted by the first temperature sensor, thereby controlling the temperature of the first heat-sealing head and keeping it within a suitable range. This avoids excessive heat sealing due to excessive temperature of the first heat-sealing head causing damage to the plastic film, or excessive temperature of the first heat-sealing head. Insufficient heat sealing due to low temperature can lead to poor sealing. The second pressure sensor detects the pressure value of the second heat sealing head and feeds the data back to the controller. The controller then controls the range of motion of the second drive unit's drive end based on the pressure data, keeping it within a suitable range. This prevents excessive pressure from deforming the plastic film or insufficient pressure from affecting the heat sealing effect. The second temperature sensor detects the temperature of the second heat sealing head and feeds the data back to the controller. The controller then controls the temperature of the second heating module based on the temperature data, thus controlling the temperature of the second heat sealing head and keeping it within a suitable range. This prevents overheating from causing film damage or underheating from causing poor sealing. The movable carrier plate can support the plastic film during heat sealing and its height is adjustable to accommodate lower heat sealing heads of different heights. The movable stop provides positioning. The cutting mechanism trims excess material, eliminating the need for manual re-cutting later. Attached Figure Description

[0020] To more clearly illustrate the technical solutions of the embodiments of this utility model, the drawings used in the embodiments will be briefly introduced below. It should be understood that the following drawings only show some embodiments of this utility model and should not be regarded as a limitation of the scope. For those skilled in the art, other related drawings can be obtained from these drawings without creative effort.

[0021] Figure 1 This is a structural schematic diagram of the present invention from a first angle;

[0022] Figure 2 This is a structural schematic diagram of the present invention from a second angle;

[0023] Figure 3 This is a structural schematic diagram of the present invention from a third angle;

[0024] Figure 4 This is a structural schematic diagram of the present invention from the fourth angle;

[0025] Figure 5 yes Figure 1 A magnified view of part A in the diagram;

[0026] Figure 6 yes Figure 1 A magnified view of part B in the diagram;

[0027] Figure 7 yes Figure 2 A magnified view of part C in the diagram.

[0028] Explanation of main component symbols

[0029] 100. Rack;

[0030] 200, First heat sealing mechanism; 210, First heat sealing head; 211, Upper heat sealing head; 212, Lower heat sealing head; 220, First driving component; 230, First pressure sensor; 240, First temperature sensor;

[0031] 300, Second heat sealing mechanism; 310, Second heat sealing head; 311, Heat sealing sheet; 312, Heat sealing block; 320, Second driving component; 330, Second pressure sensor; 340, Second temperature sensor;

[0032] 400. Controller;

[0033] 500. Carrier plate; 510. Adjusting bolt; 520. Adjusting nut;

[0034] 600, stop block; 610, slide groove;

[0035] 700. Cutting mechanism; 710. First blade; 720. Second blade; 730. Rotating cylinder. Detailed Implementation

[0036] To make the objectives, technical solutions, and advantages of the embodiments of this utility model clearer, the technical solutions of the embodiments of this utility model will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only a part of the embodiments of this utility model, not all of them. All other embodiments obtained by those skilled in the art based on the embodiments of this utility model without creative effort are within the scope of protection of this utility model. Therefore, the following detailed description of the embodiments of this utility model provided in the accompanying drawings is not intended to limit the scope of the claimed utility model, but merely represents selected embodiments of this utility model. All other embodiments obtained by those skilled in the art based on the embodiments of this utility model without creative effort are within the scope of protection of this utility model.

[0037] In this utility model, unless otherwise explicitly specified and limited, the terms "installation," "connection," "joining," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model according to the specific circumstances.

[0038] In this invention, unless otherwise explicitly specified and limited, "above" or "below" the second feature can include direct contact between the first and second features, or contact between the first and second features through another feature between them. Furthermore, "above," "over," and "on top" of the second feature includes the first feature directly above or diagonally above the second feature, or simply indicates that the first feature is at a higher horizontal level than the second feature. "Below," "below," and "under" the second feature includes the first feature directly below or diagonally below the second feature, or simply indicates that the first feature is at a lower horizontal level than the second feature.

[0039] Example

[0040] like Figures 1-7As shown, this utility model discloses a heat-sealing device for a flexible bioreactor, including a frame 100, a first heat-sealing mechanism 200 for heat-sealing a joint to a plastic film, a second heat-sealing mechanism 300 for heat-sealing the plastic film into a sealed bag, and a controller 400 disposed on the frame 100. The first heat-sealing mechanism 200 and the second heat-sealing mechanism 300 are sequentially disposed on the frame 100, and both the first heat-sealing mechanism 200 and the second heat-sealing mechanism 300 are electrically connected to the controller 400. In this utility model, the first heat-sealing mechanism 200 can heat-seal and fix the plastic joint to the plastic film, the second heat-sealing mechanism 300 can heat-seal the plastic film with the plastic joint after heat-sealing and fixation into a sealed bag, and the controller 400 can control the operation of the first heat-sealing mechanism 200 and the second heat-sealing mechanism 300.

[0041] The first heat-sealing mechanism 200 includes a first heat-sealing head 210, a first driving component 220, and a first heating module. The first driving component 220 is fixedly mounted on the frame 100. The driving end of the first driving component 220 is connected to the first heat-sealing head 210. The first heat-sealing head 210 is connected to the first heating module. Both the first heating module and the first driving component 220 are electrically connected to the controller 400. The first heating module can heat the first heat-sealing head 210 to complete the heat-sealing operation. The first driving component 220 can drive the first heat-sealing head 210 to move, thereby completing the heat-sealing and fixing process of the plastic joint and the plastic film. The controller 400 can control the movement of the first driving component 220 and the heating function of the first heating module.

[0042] The second heat-sealing mechanism 300 includes a second heat-sealing head 310, a second driving component 320, and a second heating module. The second driving component 320 is fixedly mounted on the frame 100, and its driving end is connected to the second heat-sealing head 310. The second heat-sealing head 310 is connected to the second heating module, and both the second heating module and the second driving component 320 are electrically connected to the controller 400. The second heating module can heat the second heat-sealing head 310 to complete the heat-sealing operation, and the second driving component 320 can drive the second heat-sealing head 310 to move, thereby completing the process of heat-sealing a plastic film with a plastic joint into a sealed bag. The controller 400 can control the movement of the second driving component 320 and the heating function of the second heating module.

[0043] The first heat-sealing head 210 is equipped with a first pressure sensor 230 and a first temperature sensor 240, both of which are electrically connected to the controller 400. The first pressure sensor 230 can detect the pressure value of the first heat-sealing head 210 and feed the pressure value data back to the controller 400. The controller 400 can control the range of motion of the drive end of the first drive component 220 according to the pressure value data transmitted by the first pressure sensor 230, keeping it within a suitable range. This can prevent excessive pressing force of the first heat-sealing head 210 from damaging the plastic film and plastic. Deformation of the material joint or insufficient pressing force can affect the heat sealing effect. The first temperature sensor 240 can detect the temperature of the first heat sealing head 210 and feed the temperature data back to the controller 400. The controller 400 can control the temperature of the first heating module based on the temperature value transmitted by the first temperature sensor 240, thereby controlling the temperature of the first heat sealing head 210 and keeping it within a suitable range. This avoids overheating and damage to the plastic film due to excessive heat sealing, or underheating and poor sealing due to insufficient heat sealing due to insufficient heat sealing. In addition, both the first and second heating modules are equipped with nickel-chromium alloy heating tubes, which abut against the first and second heat sealing heads 210 and 310, providing the required temperature for heat sealing.

[0044] The second heat-sealing head 310 is equipped with a second pressure sensor 330 and a second temperature sensor 340, both of which are electrically connected to the controller 400. The second pressure sensor 330 can detect the pressure value of the second heat-sealing head 310 and feed the pressure value data back to the controller 400. The controller 400 can control the range of motion of the drive end of the second drive component 320 according to the pressure value data transmitted by the second pressure sensor 330, keeping it within a suitable range. This can prevent excessive pressing force of the second heat-sealing head 310 from damaging the plastic. Membrane deformation or insufficient pressing force can affect the heat sealing effect. The second temperature sensor 340 can detect the temperature of the second heat sealing head 310 and feed the temperature data back to the controller 400. The controller 400 can control the temperature of the second heating module based on the temperature value transmitted by the second temperature sensor 340, thereby controlling the temperature of the second heat sealing head 310 and keeping the temperature of the second heat sealing head 310 within a suitable range. This can avoid the situation where the temperature of the second heat sealing head 310 is too high and overheating leads to film damage, or the temperature of the second heat sealing head 310 is too low and insufficient heat sealing leads to poor sealing.

[0045] The aforementioned first heat-sealing head 210 includes an upper heat-sealing head 211 detachably mounted on the driving end of the first driving member 220 and a lower heat-sealing head 212 detachably mounted on the frame 100. The upper heat-sealing head 211 and the lower heat-sealing head 212 are arranged opposite to each other. Both the upper heat-sealing head 211 and the lower heat-sealing head 212 are connected to the first heating module. The lower end of the upper heat-sealing head 211 and the upper end of the lower heat-sealing head 212 are provided with cavities adapted to the plastic connector. The first pressure sensor 230 is disposed at the upper end of the lower heat-sealing head 212. The first pressure sensor 230 can abut against the upper heat sealing head 211, and the first temperature sensor is set on the upper heat sealing head 211. In this embodiment, the upper heat sealing head 211 and the lower heat sealing head 212 are detachable and replaceable. Different upper heat sealing heads 211 and lower heat sealing heads 212 can be used according to different shapes of plastic joints, so that the equipment can be directly adapted to heat sealing processing of flexible bioreactor plastic membranes and plastic joints of different sizes and thicknesses without replacing the entire set of equipment, reducing the production input cost of enterprises for multiple specifications of products. Among them, the upper heat sealing head 211 is threadedly connected to the drive end of the first drive component 220, and the lower heat sealing head 212 is threadedly connected to the frame 100.

[0046] The aforementioned second heat-sealing head 310 includes a heat-sealing piece 311 mounted on the driving end of the second driving member 320 and a heat-sealing block 312 mounted on the frame 100. The heat-sealing piece 311 and the heat-sealing block 312 are arranged opposite to each other, and both the heat-sealing piece 311 and the heat-sealing block 312 are connected to the second heating module. A second pressure sensor 330 is disposed on the heat-sealing block 312 and can abut against the heat-sealing piece 311. A second temperature sensor 340 is disposed on the heat-sealing piece 311. In this embodiment, the heat-sealing piece 311 and the heat-sealing block 312 can be used to heat-seal a plastic film with a plastic joint into a sealed bag.

[0047] Both the first driving component 220 and the second driving component 320 mentioned above are selected as servo cylinders. The servo cylinders have stable driving force and rapid response. With the controller 400, they can be automatically adjusted to reduce manual intervention.

[0048] The frame 100 is equipped with a movable carrier plate 500, which corresponds to the lower heat-sealing head 212. The frame 100 is equipped with adjusting bolts 510, located on both sides of the lower heat-sealing head 212. The carrier plate 500 has through holes through which it passes onto the adjusting bolts 510. Adjusting bolts 510 are equipped with adjusting nuts 520, which are threadedly connected to the adjusting bolts 510. The upper end face of the adjusting nut 520 abuts against the lower end face of the carrier plate 500. In this embodiment, the movable carrier plate 500 can support the plastic film during heat sealing of the plastic film and plastic joint, eliminating the need for operators to constantly hold and stretch the plastic film. The adjusting bolts 510 and adjusting nuts 520 work together to adjust the height of the carrier plate 500 to match the lower heat-sealing head 212. Thus, when replacing the lower heat-sealing head 212 with a different height, simply rotating the adjusting nut 520 will allow the carrier plate 500 to adapt to the height of the lower heat-sealing head 212.

[0049] The frame 100 is provided with a movable stop 600, which corresponds to the second heat sealing head 310. A slide groove 610 is provided on the frame 100. A slider is provided at the bottom of the movable stop 600. The slider is inserted into the slide groove 610 and is slidably connected to the slide groove 610. The movable stop 600 can slide along the length of the slide groove 610. In this embodiment, the movable stop 600 slides through the cooperation of the slider and the slide groove 610. The slide groove 610 forms a guide limit for the slider to avoid the block 600 from shifting and causing the bag positioning deviation.

[0050] The frame 100 is equipped with a cutting mechanism 700, which is located between the second heat-sealing head 310 and the movable stop 600. The cutting mechanism 700 includes a first blade 710, a second blade 720, and a rotary cylinder 730. Both the first blade 710 and the second blade 720 have cutting edges. The first blade 710 and the rotary cylinder 730 are fixedly mounted on the frame 100. The second blade 720 is located above the first blade 710, and the cutting edges of the first blade 710 and the second blade 720 are positioned opposite each other. The rotating shaft of the rotary cylinder 730 is connected to the second blade 720, and the rotary cylinder 730 can drive... The second cutter 720 rotates toward the first cutter 710, and the rotating cylinder 730 is electrically connected to the controller 400. In this embodiment, some excess material remains on the edge of the heat-sealed flexible bioreactor bag. The controller 400 can control the rotating cylinder 730 to work. The rotating shaft of the rotating cylinder 730 rotates, which in turn drives the second cutter 720 connected to the rotating shaft of the rotating cylinder 730 to move toward the first cutter 710, thereby cutting off the excess material without the need for manual re-cutting later.

[0051] The above are merely preferred embodiments of this utility model and are not intended to limit the scope of this utility model. Various modifications and variations can be made to this utility model by those skilled in the art. Any modifications, equivalent substitutions, or improvements made within the spirit and principles of this utility model should be included within the protection scope of this utility model.

Claims

1. A heat-sealing device for a flexible bioreactor, characterized in that, The device includes a frame, a first heat-sealing mechanism for heat-sealing a connector to a plastic film, a second heat-sealing mechanism for heat-sealing the plastic film into a sealed bag, and a controller mounted on the frame. The first heat-sealing mechanism and the second heat-sealing mechanism are sequentially mounted on the frame, and both the first heat-sealing mechanism and the second heat-sealing mechanism are electrically connected to the controller. The first heat-sealing mechanism includes a first heat-sealing head, a first driving component, and a first heating module. The first driving component is fixedly mounted on the frame. The driving end of the first driving component is connected to the first heat-sealing head. The first heat-sealing head is connected to the first heating module. Both the first heating module and the first driving component are electrically connected to the controller. The second heat-sealing mechanism includes a second heat-sealing head, a second driving component, and a second heating module. The second driving component is fixedly mounted on the frame. The driving end of the second driving component is connected to the second heat-sealing head. The second heat-sealing head is connected to the second heating module. Both the second heating module and the second driving component are electrically connected to the controller. The first heat-sealing head is equipped with a first pressure sensor and a first temperature sensor, both of which are electrically connected to the controller. The second heat-sealing head is equipped with a second pressure sensor and a second temperature sensor, both of which are electrically connected to the controller.

2. The heat sealing device for a flexible bioreactor according to claim 1, characterized in that; The first heat sealing head includes an upper heat sealing head that is detachably installed on the driving end of the first driving component and a lower heat sealing head that is detachably installed on the frame. The upper heat sealing head and the lower heat sealing head are arranged opposite to each other, and both the upper heat sealing head and the lower heat sealing head are connected to the first heating module.

3. The heat sealing device for a flexible bioreactor according to claim 1, characterized in that; The second heat-sealing head includes a heat-sealing sheet mounted on the driving end of the second driving component and a heat-sealing block mounted on the frame. The heat-sealing sheet and the heat-sealing block are arranged opposite to each other, and both the heat-sealing sheet and the heat-sealing block are connected to the second heating module.

4. A heat-sealing device for a flexible bioreactor according to claim 1, characterized in that; Both the first driving component and the second driving component are selected as servo cylinders.

5. A heat-sealing device for a flexible bioreactor according to claim 2, characterized in that: The frame is equipped with a movable carrier plate, which is positioned corresponding to the lower heat sealing head.

6. A heat-sealing device for a flexible bioreactor according to claim 1, characterized in that: The frame is provided with a movable stop, which is configured to correspond to the second heat sealing head.

7. A heat-sealing device for a flexible bioreactor according to claim 5, characterized in that: The frame is provided with adjusting bolts, which are located on both sides of the lower heat sealing head. The carrier plate has through holes, and the carrier plate passes through the through holes onto the adjusting bolts. The adjusting bolts are provided with adjusting nuts, which are threadedly connected to the adjusting bolts. The upper end face of the adjusting nut abuts against the lower end face of the carrier plate.

8. A heat-sealing device for a flexible bioreactor according to claim 6, characterized in that: The frame is equipped with a cutting mechanism, which is located between the second heat-sealing head and the stop block.

9. A heat-sealing device for a flexible bioreactor according to claim 8, characterized in that: The cutting mechanism includes a first blade, a second blade, and a rotary cylinder. Both the first blade and the second blade are provided with cutting edges. Both the first blade and the rotary cylinder are fixedly mounted on the frame. The second blade is located above the first blade. The cutting edges of the first blade and the second blade are arranged opposite to each other. The rotating shaft of the rotary cylinder is connected to the second blade. The rotary cylinder can drive the second blade to rotate toward the first blade. The rotary cylinder is electrically connected to the controller.

10. A heat-sealing device for a flexible bioreactor according to claim 6, characterized in that: The frame is provided with a sliding groove, and the bottom of the stop is provided with a slider. The slider is inserted into the sliding groove, and the stop is slidably connected to the sliding groove.

Images