Antibody tube with cap opening guard

Abstract

The utility model discloses an antibody pipe with uncapping protection device relates to biological experiment equipment technical field. The device is innovatively integrated adsorption protection component on the basis of traditional antibody pipe structure, and effectively solves the technical problem of aerosol leakage when uncapping. The device comprises a pipe body, a top cover connected through a flexible connecting piece, and an adsorption assembly arranged on the top cover. The adsorption assembly comprises a connecting pipe, an adsorption air bag and a critical sealing element. The sealing element comprises a plurality of plastic flap pieces with sealing strips to form a normally closed sealing structure. During use, the accumulated aerosol in the pipe body can be actively adsorbed into the air bag by squeezing and releasing the adsorption air bag before opening the top cover, thereby reducing aerosol leakage. The utility model has a reasonable structure design, simple and convenient operation, and significantly improves the biological safety of experimental operation and the reliability of sample protection.

Description

Technical Field

[0001] This utility model relates to the field of biological experimental equipment technology, specifically to an antibody tube with a cap-opening protection device. Background Technology

[0002] Antibody tubes are commonly used sample storage containers in biomedical laboratories. They are widely used in experiments such as ELISA detection, immunohistochemistry, and cell culture to store serum, cell culture supernatant, and other biological samples containing antibodies.

[0003] Currently, in laboratory experiments, when antibody tubes need to be opened, the pressure difference between the inside and outside of the tube, sample evaporation, and other factors can cause the aerosols accumulated inside the tube to leak out rapidly upon opening. These aerosols may contain biologically active antibody components, pathogenic microorganisms, or other harmful substances, which can cause the following serious problems: First, aerosol leakage can lead to cross-contamination between samples, affecting the accuracy and reproducibility of experimental results. In high-throughput screening experiments, contamination of one sample may affect the test results of the entire batch, causing experimental deviation.

[0004] Secondly, the loss of valuable samples is also a significant problem facing current technologies. The loss of some rare antibodies or valuable clinical samples in aerosol form, although small in quantity per instance, will result in significant material waste in the long run. Summary of the Invention

[0005] To address the shortcomings of existing technologies, this invention provides an antibody tube with an opening protection device, which solves the problems of sample contamination, biosafety risks, and loss of valuable samples caused by aerosol leakage during the opening process of existing antibody tubes.

[0006] To achieve the above objectives, this utility model is implemented through the following technical solution: an antibody tube with an opening protection device, comprising a tube body, a top cap provided on the top of the tube body, and an adsorption component provided on the top of the top cap; The adsorption assembly includes a connecting tube, an adsorption bladder, and a sealing element; the top of the connecting tube is provided with an adsorption bladder, and the inner cavity of the connecting tube is provided with a sealing element. The sealing element includes multiple plastic flaps, which are bonded together to form a normally closed state, effectively ensuring the sealing performance of the device; each of the bonding edges of the plastic flaps is provided with a sealing strip, which together constitutes a reliable sealing interface.

[0007] Furthermore, the top of the top cover has a through hole, which is connected to the inner cavity of the tube to provide a channel for the adsorption operation.

[0008] Furthermore, the connecting tube is fixed to the through hole on the top of the top cover by a snap-fit ​​method, enabling quick assembly and disassembly.

[0009] Furthermore, multiple plastic flaps are fixedly connected to the inner wall of the connecting tube to form a stable sealing structure.

[0010] Furthermore, the top cover and the tube body are connected by a flexible connector, which ensures both ease of use and effective prevention of top cover loss.

[0011] Furthermore, the tube is equipped with graduation lines to facilitate precise control of the sample volume during the experiment.

[0012] This invention provides an antibody tube with a cap-opening protection device. Compared with the prior art, it has the following advantages: This antibody tube with an opening protection device can effectively adsorb and seal the aerosol inside the tube before opening by the synergistic effect of the adsorption airbag and the sealing element, reducing aerosol leakage. It solves the sample contamination and biosafety problems caused by aerosol leakage when opening existing antibody tubes, and is simple in structure and easy to operate. Attached Figure Description

[0013] Figure 1 This is a schematic diagram of the structure of this utility model; Figure 2 This is a schematic diagram showing the structural breakdown of this utility model; Figure 3 This is a partial cross-sectional view of the structure of this utility model; Figure 4 This is a schematic diagram of the adsorption component structure of this utility model; Figure 5 This is a schematic diagram of the sealing component of this utility model.

[0014] In the diagram: 1. Tube body; 2. Flexible connector; 3. Top cover; 4. Adsorption assembly; 41. Connecting tube; 42. Adsorption airbag; 43. Sealing component; 431. Plastic flap; 432. Sealing strip. Detailed Implementation

[0015] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0016] Please see Figures 1 to 5This utility model provides a technical solution: an antibody tube with an opening protection device, comprising a tube body 1, a flexible connector 2, a top cap 3, and an adsorption assembly 4.

[0017] Structural features of tube 1: The tube 1 is made of medical-grade silicone or Teflon material. The outer wall of the tube 1 is provided with precise graduation lines, with a graduation range from 0.1mL to 5.0mL and a minimum graduation value of 0.1mL. The top opening of the tube 1 is provided with an interface for fitting with the top cap 3. The bottom of the tube 1 is tapered to facilitate sample collection and aspiration.

[0018] Top cover 3 and connecting structure: The top cover 3 is connected to the tube body 1 via a flexible connector 2. The flexible connector 2 is a strip structure made of medical-grade silicone material. One end of the connector is fixed to the upper part of the outer wall of the tube body 1 by heat fusion, and the other end is fixed to the side wall of the top cover 3 in the same way. It has sufficient flexibility to ensure that the top cover 3 will not detach from the tube body 1 when it is opened, while avoiding interference with operation.

[0019] A through hole is provided at the center of the top of the top cover 3. The through hole is directly connected to the inner cavity of the tube body 1. The inner wall of the through hole is used to form a tight snap-fit ​​with the connecting tube 41 of the adsorption component 4.

[0020] Detailed structure of adsorption component 4: The adsorption component 4 includes a connecting tube 41, an adsorption airbag 42, and a sealing element 43. The adsorption component 4 is for single use and cannot be reused. The adsorption component 4 is provided with different specifications and can be used for tubes 1 of different sizes to accommodate different sample volumes. The airbag capacity of the adsorption airbag 42 can be selected according to the amount of aerosol in the inner cavity of the tube 1 to increase the capacity of the adsorption airbag.

[0021] The connecting tube 41 is a hollow tubular structure made of medical-grade ABS material. Its lower outer wall is provided with an annular end, which matches the inner wall of the through hole 3 of the top cover to form a reliable snap-fit ​​connection.

[0022] The adsorption airbag 42 is fixedly connected to the top of the connecting tube 41. It is made of medical silicone material with good elasticity and is in a semi-inflated state in its natural state. The outer surface of the adsorption airbag 42 is provided with anti-slip texture, which makes it easy for the operator to hold.

[0023] The core technical features of the seal 43: The seal 43 is located in the lower part of the inner cavity of the connecting pipe 41, and includes three plastic flaps 431 and a sealing strip 432.

[0024] Three plastic flaps 431 are evenly distributed at 120° on the inner wall of the connecting tube 41. The fixed end of each plastic flap 431 is fixed to the inner wall of the connecting tube 41 by ultrasonic welding, and the free end extends towards the center and fits together. The plastic flaps 431 are made of medical-grade polyurethane material, which has good elasticity and resilience.

[0025] The sealing strip 432 is set on the edge of the contact side of each plastic flap 431. It is a strip structure made of silicone material with a semi-circular cross section. When the three plastic flaps 431 are in contact with each other, the three sealing strips 432 together form a complete circular sealing interface, ensuring the reliability of the seal.

[0026] Working principle and operating procedures: Step 1: Equipment Preparation Inject the sample to be tested into tube 1, with the sample volume not exceeding 80% of the maximum capacity of tube 1. Tightly cover the top cover 3 onto the interface of tube 1, at which point the through hole at the top of the top cover 3 is sealed by an independent sealing cap (not shown in the figure).

[0027] Step Two: Detection Process The tube containing the sample is placed in the testing instrument for testing. During the testing process, the tube may undergo rotation, shaking and other movements. The volatile components in the sample will form aerosols and accumulate in the top space of the tube.

[0028] Step 3: Adsorption Operation After the test is completed, before opening the top cover 3, first remove the independent sealing cap on the through hole, and then insert the lower end of the connecting tube 41 of the adsorption component 4 into the through hole of the top cover 3 so that the connecting tube 41 and the top cover 3 form a reliable snap-fit.

[0029] The operator pinches the adsorption airbag 42 with their thumb and forefinger to expel the air inside. During the pinching process, the air pressure inside the adsorption airbag 42 increases, and the airflow pushes the plastic flaps 431 downward, causing the free ends of the three plastic flaps 431 to bend outward and open, forming an airflow channel.

[0030] Step 4: Aerosol Adsorption Slowly release the adsorption bladder 42. Due to the elastic restoring force of the adsorption bladder 42, a negative pressure is formed inside. This negative pressure is transmitted to the inner cavity of the tube body 1 through the opened plastic flap 431, drawing the aerosol accumulated at the top of the tube body 1 into the adsorption bladder 42. This process can be repeated 2-3 times to ensure that the aerosol in the tube body 1 is fully adsorbed.

[0031] Step 5: Maintain the seal When the operation of the adsorption bladder 42 is stopped, the plastic flaps 431 return to their initial mutually adhering state due to their own elasticity. At the same time, the sealing strip 432 forms a tight sealing interface to prevent the aerosol captured in the adsorption bladder 42 from leaking back and to prevent external pollutants from entering the tube 1.

[0032] Step 6: Open the lid safely After aerosol adsorption is completed, the top cover 3 can be opened directly for subsequent operations. Since the aerosol in the tube 1 has been greatly reduced, the risk of aerosol leakage when the cover is opened is significantly reduced, effectively protecting the safety of operators and the environment.

[0033] It should be noted that, in this document, relational terms such as "first" and "second" are used merely to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such a process, method, article, or apparatus. Without further limitations, the phrase "comprising an element defined as..." does not exclude the presence of other identical elements in the process, method, article, or apparatus that includes said element.

[0034] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. An antibody tube with a cap-opening protection device, comprising a tube body (1), characterized in that: The top of the tube (1) is provided with a top cover (3), and the top of the top cover (3) is provided with an adsorption component (4). The adsorption assembly (4) includes a connecting tube (41), an adsorption airbag (42) is provided at the top of the connecting tube (41), and a sealing element (43) is provided in the inner cavity of the connecting tube (41). The sealing element (43) includes multiple plastic flaps (431), which are bonded together to form a normally closed state. Each of the plastic flaps (431) has a sealing strip (432) on its bonding edge, forming a sealing interface.

2. An antibody tube with a cap-opening protection device according to claim 1, characterized in that: The top of the top cover (3) has a through hole, and the through hole is connected to the inner cavity of the tube body (1). The through hole is sealed by an independent sealing cap.

3. An antibody tube with an opening protection device according to claim 2, characterized in that: The connecting pipe (41) is snapped into the through hole at the top of the top cover (3).

4. An antibody tube with an opening protection device according to claim 1, characterized in that: Multiple plastic flaps (431) are fixedly connected to the inner wall of the connecting tube (41).

5. An antibody tube with an opening protection device according to claim 1, characterized in that: The top cover (3) and the tube body (1) are connected by a flexible connector (2).

6. An antibody tube with an opening protection device according to claim 1, characterized in that: The tube (1) is provided with scale lines.

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