Integrated stirring fermentation tank with built-in aeration function

Abstract

The utility model relates to biological fermentation technical field especially relates to a built -in aeration function integrated stirring fermentation tank, it includes: the jar body, the top cover of jar body is provided with gas import; power unit, power unit sets up in the outer bottom surface of jar body, stirring unit, stirring unit sets up in the cavity of jar body, and stirring unit includes hollow stirring shaft and a plurality of fusion formula stirring paddle, wherein, the top end of hollow stirring shaft is connected gas import, and the bottom end is connected in power unit, fusion formula stirring paddle is vertically and even interval setting between the top end and bottom end of hollow stirring shaft, and a plurality of vent holes are arranged on the paddle blade, the inside of fusion formula stirring paddle is hollow, and the cavity of fusion formula stirring paddle is communicated in the inner chamber of hollow stirring shaft, the built -in aeration function integrated stirring fermentation tank of the utility model realizes high -efficient oxygen dissolving through the simplified fermentation tank structure, and the efficiency of mixing is improved.

Description

Technical Field

[0001] This utility model relates to the field of bio-fermentation technology, and in particular to an integrated stirred fermenter with built-in aeration function. Background Technology

[0002] A fermenter is a device used for microbial fermentation.

[0003] Currently, bioreactors consist of a tank body, a mechanical stirrer, an air distributor (e.g., a ring pipe or bubbler), and electrodes for monitoring temperature, pH, and dissolved oxygen. The mechanical stirrer, air distributor, pH electrode, dissolved oxygen electrode, and temperature electrode are independently installed within the tank body; this has the following drawbacks: (1) Low dissolved oxygen efficiency: The independently set air distributor releases large bubbles with a small contact area with the fermentation broth, and they tend to accumulate in the stirring blind zone, resulting in low oxygen mass transfer efficiency (K). L a) The oxygen content is not high enough to meet the oxygen demand of high-density cultivation.

[0004] (2) Small effective volume: The independent mechanical agitator, air distributor and multiple monitoring electrodes occupy a large amount of space in the fermenter, reducing the effective liquid volume in the fermenter and reducing the yield per batch.

[0005] (3) High cleaning difficulty: The independent setting of multiple components results in a complex internal structure of the fermenter, which can easily create dead corners for cleaning and sterilization, increasing the risk of contamination and production costs.

[0006] (4) Poor monitoring accuracy: Inserting electrodes (e.g., temperature electrode, dissolved oxygen electrode and pH electrode) from the top of the fermenter will cause the electrodes to be interfered with by the mechanical agitator, and the measurement points may not be able to fully reflect the overall culture environment inside the fermenter.

[0007] Therefore, finding a fermenter that can improve dissolved oxygen efficiency, increase effective volume, simplify internal structure, and facilitate cleaning has become a research hotspot. Utility Model Content

[0008] To solve at least one of the above-mentioned technical problems, this utility model provides an integrated stirred fermenter with built-in aeration function.

[0009] In one aspect, this utility model provides an integrated stirred fermenter with built-in aeration function. The integrated stirred fermenter with built-in aeration function includes: a tank body, the top cover of which is provided with a gas inlet; a power unit, which is disposed on the outer bottom surface of the tank body; and a stirring unit, which is disposed in the cavity of the tank body. The stirring unit includes a hollow stirring shaft and multiple fused stirring blades. The top end of the hollow stirring shaft is connected to the gas inlet, and the bottom end is connected to the power unit. The fused stirring blades are vertically and evenly spaced between the top and bottom ends of the hollow stirring shaft, and the blades are provided with multiple vent holes. The interior of the fused stirring blades is hollow, and the cavity of the fused stirring blades is connected to the inner cavity of the hollow stirring shaft.

[0010] In some embodiments, the structure of the fusion impeller is selected from at least one of a disc turbine type, a paddle type, and a spiral type.

[0011] In some embodiments, the vent holes have a diameter of 0.1~0.5 mm and are evenly distributed on the surface of the impeller blades of the fusion stirring paddle.

[0012] In some embodiments, the system further includes a rake-type defoamer disposed at the upper end of the hollow stirring shaft.

[0013] In some embodiments, a sampling port is also provided at the bottom of the side wall of the tank.

[0014] In some embodiments, the system further includes a monitoring unit disposed on the lower part of the tank sidewall.

[0015] In some embodiments, the monitoring unit includes a pH electrode, a dissolved oxygen electrode, and a temperature electrode.

[0016] In some embodiments, the top cover of the tank is also provided with a feed inlet, a replenishment inlet, an inoculation inlet, a condenser, and a foam electrode at intervals.

[0017] In some embodiments, the power unit is a drive motor.

[0018] In some embodiments, the power unit further includes a heating device.

[0019] The technical solution provided by this utility model has the following advantages: (1) Improved oxygen dissolution and mixing efficiency: The integrated stirred fermenter of this invention can efficiently dissolve oxygen and mix. Specifically, sterile air enters directly into the cavity of the fusion stirring paddle through the hollow stirring shaft from the gas inlet and is released from the vent holes of the paddle blades. Due to the high-speed rotation of the fusion stirring paddle, the released bubbles are immediately sheared and broken into finer bubbles, which greatly increases the gas-liquid contact area, significantly improves the oxygen mass transfer efficiency and dissolved oxygen level, and further improves the uniformity of the liquid in the fermenter.

[0020] (2) Increase the effective volume: The integrated stirring fermentation tank of this utility model saves space and increases the effective volume. Specifically, the traditional bottom air distributor is eliminated and multiple electrodes are integrated on the side wall, making the bottom and central area of ​​the tank simpler and reducing the space occupied by internal components. Thus, more fermentation liquid can be loaded in the same tank volume, increasing the single output.

[0021] (3) Simplify the structure of the fermenter and reduce the difficulty of sterilization and cleaning: The integrated stirred fermenter of this utility model has a simplified structure and is easy to clean and sterilize. Specifically, the integrated stirring and aeration design reduces the number of independent parts inside the tank. The interior is smooth and there are no complicated pipelines, which greatly reduces the dead corners for cleaning and sterilization, reduces the risk of contamination, and meets the requirements of aseptic production.

[0022] (4) Improve the readiness of monitoring: The monitoring unit, consisting of pH electrode, dissolved oxygen electrode and temperature electrode, is set at an appropriate depth in the lower part of the side wall of the tank, which can better monitor the property parameters of the main fermentation liquid in the fermenter. Attached Figure Description

[0023] The accompanying drawings, which are incorporated in and form part of this specification, illustrate embodiments consistent with the present invention and, together with the description, serve to explain the principles of the present invention.

[0024] To more clearly illustrate the technical solutions in the embodiments of this utility model, the drawings used in the description of the embodiments will be briefly introduced below. Obviously, for those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0025] Figure 1 This is a schematic diagram of the structure of an integrated stirred fermenter with built-in aeration function according to an embodiment of the present invention. Figure 2 This is a top view of the lid of the integrated stirred fermenter with built-in aeration function according to an embodiment of the present invention.

[0026] Figure label: 1-Tank body; 2-Gas inlet; 3-Power unit; 4-Hollow stirring shaft; 5-Mixing stirring paddle; 6-Rake defoamer; 7-Sampling port; 8-Monitoring unit; 9-pH electrode; 10-Dissolved oxygen electrode; 11-Temperature electrode; 12-Feed inlet; 13-Replenishment port; 14-Inoculation port; 15-Condenser; 16-Foam electrode. Detailed Implementation

[0027] To better understand the above-mentioned objectives, features, and advantages of this utility model, the solution of this utility model will be further described below. It should be noted that, unless otherwise specified, the embodiments of this utility model and the features thereof can be combined with each other.

[0028] Many specific details are set forth in the following description in order to provide a full understanding of the present invention, but the present invention may also be implemented in other ways different from those described herein; obviously, the embodiments in the specification are only some embodiments of the present invention, and not all embodiments.

[0029] The following is combined Figure 1 and Figure 2 The technical solution provided by this utility model will be described in more detail.

[0030] See Figure 1 An integrated stirred fermenter with built-in aeration function includes: a tank body 1, with a gas inlet 2 on the top cover of the tank body 1; a power unit 3, located on the outer bottom surface of the tank body 1; and a stirring unit, located within the cavity of the tank body 1, comprising a hollow stirring shaft 4 and multiple fused stirring blades 5. The top end of the hollow stirring shaft 4 is connected to the gas inlet 2, and the bottom end is connected to the power unit 3. The fused stirring blades 5 are vertically and evenly spaced between the top and bottom ends of the hollow stirring shaft 4, and each blade has multiple ventilation holes. The interior of each fused stirring blade 5 is hollow, and its cavity connects to the inner cavity of the hollow stirring shaft 4. A monitoring unit 8 is located on the lower part of the side wall of the tank body 1, and includes a pH electrode 9, a dissolved oxygen electrode 10, and a temperature electrode 11. The pH electrode 9, dissolved oxygen electrode 10, and temperature electrode 11 are all located below the liquid surface and are used for real-time monitoring and control of the fermentation process.

[0031] See Figure 2 The integrated stirred fermenter with built-in aeration function has a gas inlet 2, a feed inlet 12, a replenishment inlet 13, an inoculation inlet 14, a condenser 15, and a foam electrode 16 on its lid. The feed inlet 12 is used to add the fermentation raw materials into the tank 1; the replenishment inlet 13 is used to add reagents into the tank 1 during fermentation to change the fermentation environment; the inoculation inlet 14 is used to add the inoculum into the tank 1; the condenser 15 is used to maintain the fermentation temperature of the tank 1; and the foam electrode 16 is used to monitor excessive foaming during the fermentation process within the tank 1 and can automatically add an appropriate amount of defoamer as needed.

[0032] During operation, the power unit 3 drives the hollow stirring shaft 4 and the fusion stirring paddle 5 to rotate together. At the same time, sterile compressed air is introduced from the gas inlet 2, passes through the hollow stirring shaft 4, and finally enters the cavity of the fusion stirring paddle 5, and is evenly released from the vent holes on the blades of the fusion stirring paddle; the released bubbles are broken into a large number of fine bubbles under the shearing force of the blades of the high-speed rotating fusion stirring paddle, and quickly dissolve into the fermentation broth.

[0033] In summary, the integrated stirred fermenter with built-in aeration function of this utility model effectively improves dissolved oxygen efficiency, increases the effective liquid capacity of the fermenter, and simplifies the internal structure by integrating stirring and aeration functions and optimizing the sensor layout.

[0034] It should be noted that, in this document, relational terms such as "first" and "second" are used merely to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such a process, method, article, or apparatus. Without further limitations, an element defined by the phrase "comprising one..." does not exclude the presence of other identical elements in the process, method, article, or apparatus that includes said element.

[0035] The above description is merely a specific embodiment of the present invention, enabling those skilled in the art to understand or implement the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the general principles defined herein may be implemented in other embodiments without departing from the spirit or scope of the present invention. Therefore, the present invention is not to be limited to the embodiments described herein, but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.

Claims

1. An integrated stirred fermenter with built-in aeration function, characterized in that, The integrated stirred fermenter with built-in aeration function includes: Tank (1), the top cover of which is provided with a gas inlet (2); Power unit (3), the power unit is disposed on the outer bottom surface of tank (1); A stirring unit is disposed in the cavity of the tank (1), and the stirring unit includes a hollow stirring shaft (4) and multiple fusion stirring paddles (5). The top end of the hollow stirring shaft (4) is connected to the gas inlet (2), and the bottom end is connected to the power unit (3). The fusion-type stirring paddle (5) is vertically and evenly spaced between the top and bottom ends of the hollow stirring shaft (4), and the paddle blade is provided with multiple ventilation holes. The interior of the fusion stirring paddle (5) is hollow, and the cavity of the fusion stirring paddle (5) is connected to the inner cavity of the hollow stirring shaft (4).

2. The integrated stirred fermenter with built-in aeration function according to claim 1, characterized in that, The structure of the fusion stirring paddle (5) is selected from at least one of the following: disc turbine, paddle, and spiral structures.

3. The integrated stirred fermenter with built-in aeration function according to claim 1 or 2, characterized in that, The vent holes have a diameter of 0.1~0.5mm and are evenly distributed on the blade surface of the fusion stirring paddle (5).

4. The integrated stirred fermenter with built-in aeration function according to any one of claims 1 to 3, characterized in that, Also includes: A rake-type defoamer (6) is located at the upper end of the hollow stirring shaft (4).

5. The integrated stirred fermenter with built-in aeration function according to any one of claims 1 to 4, characterized in that, The bottom of the side wall of the tank (1) is also provided with a sampling port (7).

6. The integrated stirred fermenter with built-in aeration function according to any one of claims 1 to 5, characterized in that, Also includes: Monitoring unit (8) is located on the lower part of the side wall of the tank (1).

7. The integrated stirred fermenter with built-in aeration function according to claim 6, characterized in that, The monitoring unit includes a pH electrode (9), a dissolved oxygen electrode (10), and a temperature electrode (11).

8. The integrated stirred fermenter with built-in aeration function according to any one of claims 1 to 7, characterized in that, The top cover of the tank (1) is also provided with a feed inlet (12), a replenishment inlet (13), an inoculation inlet (14), a condenser (15), and a foam electrode (16) at intervals.

9. The integrated stirred fermenter with built-in aeration function according to any one of claims 1 to 8, characterized in that, The power unit is a drive motor.

10. The integrated stirred fermenter with built-in aeration function according to claim 9, characterized in that, The power unit also includes a heating device.

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