An immune cell detection sampling device
Patent Information
- Application Number
- CN202522378087.2
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-11-10
- Publication Date
- 2026-09-25
- Estimated Expiration
- 2035-11-10
AI Technical Summary
但这类工具清洁维护性差:取样后需拆下筒盖清理,操作繁琐;且内壁易附着废液,残留液体不仅污染后续样本,还可能破坏免疫细胞活性,导致检测数据偏差,为此,我们提出一种免疫细胞检测取样装置
[0011]与现有技术相比,本实用新型的有益效果是:储液罐与抽水泵通过弹性导水管可注入清洁液,配合气泵与弹性导液管抽吸废液,无需拆卸筒盖即可清洁内壁,避免残留污染,单向通道防止液体回流,限位板抵槽稳定操作;整体简化清洁流程,减少样本污染与细胞活性破坏,提升取样与检测准确性。
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Figure CN224798889U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of cell sampling technology, specifically to an immune cell detection and sampling device. Background Technology
[0002] Immune cells are cells that participate in or are related to the immune response, such as T cells, B cells, and NK cells. They have the function of recognizing and eliminating foreign substances (such as pathogens and tumor cells). Detection and sampling devices are used to accurately obtain immune cell samples to analyze their activity, quantity, etc., which is the basis for immune research and clinical diagnosis.
[0003] Currently, sampling mostly relies on syringes to extract samples. However, these tools are difficult to clean and maintain: the cap needs to be removed for cleaning after sampling, which is cumbersome; and waste liquid easily adheres to the inner wall. The residual liquid not only contaminates subsequent samples but may also damage the activity of immune cells, leading to deviations in test data. Therefore, we propose an immune cell detection sampling device. Utility Model Content
[0004] The purpose of this invention is to provide an immune cell detection and sampling device to solve the problems mentioned in the background art.
[0005] To achieve the above objectives, the present invention provides the following technical solution: an immune cell detection sampling device, comprising a sampling cylinder and a cylinder cover threadedly connected to the open end of the sampling cylinder, wherein a sampling head is embedded at the bottom end of the sampling cylinder, a piston rod is slidably connected through the top end of the cylinder cover, a piston is fixedly connected to the bottom end of the piston rod, and a pressing plate is fixedly connected to the top end of the piston rod;
[0006] Limiting plates are fixedly connected to the upper ends of both sides of the outer wall of the cylinder cover. A support plate is fixedly connected to the lower end of the outer wall of the cylinder cover. A liquid storage tank is fixedly connected to the top of one side of the support plate. A water pump is fixedly connected to the top of the liquid storage tank. An elastic water guide pipe is fixedly connected to the output end of the water pump. A waste liquid tank is fixedly connected to the top of the support plate. An air pump is fixedly connected to the top of the waste liquid tank. An elastic liquid guide pipe is fixedly connected to the output end of the air pump. Both the elastic liquid guide pipe and the elastic water guide pipe extend to the bottom of the piston.
[0007] Preferably, the upper end of the outer wall of the tube cap is provided with grooves, and the sampling tube and tube cap are made of transparent material.
[0008] Preferably, both the elastic liquid guide tube and the elastic water guide tube are movably connected to the top of the cylinder cover, and both the elastic liquid guide tube and the elastic water guide tube are unidirectional channels.
[0009] Preferably, the bottom of each limiting plate is fixedly connected with an abutment groove.
[0010] Preferably, an inlet pipe is embedded on one side of the top of the storage tank, and an outlet pipe is embedded at the bottom of the waste tank.
[0011] Compared with the prior art, the beneficial effects of this utility model are: the storage tank and the water pump can inject cleaning liquid through the elastic water guide tube, and the waste liquid can be drawn out with the air pump and the elastic water guide tube. The inner wall can be cleaned without removing the cylinder cover, avoiding residual pollution. The one-way channel prevents liquid backflow, and the limiting plate stabilizes the operation. The overall cleaning process is simplified, sample contamination and cell activity damage are reduced, and the accuracy of sampling and detection is improved. Attached Figure Description
[0012] Figure 1 This is a schematic diagram of the structure of this utility model;
[0013] Figure 2 This is a cross-sectional structural diagram of the sampling cylinder and cylinder cover of this utility model;
[0014] Figure 3 This is a cross-sectional view of the cylindrical cover of this utility model.
[0015] In the diagram: 1. Sampling cylinder; 11. Sampling head; 2. Cylinder cover; 201. Abutment groove; 21. Piston rod; 22. Piston; 23. Pressing plate; 24. Limiting plate; 25. Support plate; 3. Storage tank; 30. Inlet pipe; 31. Water pump; 32. Flexible water guide pipe; 4. Waste liquid tank; 40. Outlet pipe; 41. Air pump; 42. Flexible water guide pipe. Detailed Implementation
[0016] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.
[0017] Please see Figure 1-3 The present invention provides the following technical solution:
[0018] Example 1: An immune cell detection sampling device includes a sampling cylinder 1 and a cylinder cap 2 threadedly connected to the open end of the sampling cylinder 1. A sampling head 11 is embedded at the bottom end of the sampling cylinder 1. A piston rod 21 is slidably connected through the top end of the cylinder cap 2. A piston 22 is fixedly connected to the bottom end of the piston rod 21. A pressing plate 23 is fixedly connected to the top end of the piston rod 21. The upper end of the outer wall of the cylinder cap 2 is provided with grooves. The sampling cylinder 1 and the cylinder cap 2 are made of transparent material.
[0019] When using, first hold the sampling cylinder 1 and the concave area of the cap 2. Unscrew the cap 2 to check the inside of the sampling cylinder 1. First, pull the piston rod 21 upward to move the piston 22 upward and create negative pressure. Then, use the sampling head 11 to extract the immune cell sample source. Finally, press the pressing plate 23 to push the piston 22 downward to complete the sampling. The transparent material allows for direct observation of the sample volume.
[0020] Example 2: The technical solution of this example, which differs from Example 1, includes: limiting plates 24 are fixedly connected to the upper ends of both sides of the outer wall of the cylinder cover 2; a support plate 25 is fixedly connected to the lower end of the outer wall of the cylinder cover 2; a liquid storage tank 3 is fixedly connected to the top of one side of the support plate 25; a water pump 31 is fixedly connected to the top of the liquid storage tank 3; an elastic water guide pipe 32 is fixedly connected to the output end of the water pump 31; a waste liquid tank 4 is fixedly connected to the top of the support plate 25; an air pump 41 is fixedly connected to the top of the waste liquid tank 4; and an elastic water guide pipe 42 is fixedly connected to the output end of the air pump 41. Both the elastic liquid guide tube 42 and the elastic water guide tube 32 extend to the bottom of the piston 22. Both the elastic liquid guide tube 42 and the elastic water guide tube 32 are movably connected to the top of the cylinder cover 2. Both the elastic liquid guide tube 42 and the elastic water guide tube 32 are unidirectional channels. The bottom of the limiting plate 24 is fixedly connected to the groove 201. The top side of the liquid storage tank 3 is embedded with an inlet pipe 30, and the bottom of the waste liquid tank 4 is embedded with an outlet pipe 40. Since the elastic liquid guide tube 42 and the elastic water guide tube 32 are made of elastic material and are movably connected to the cylinder cover 2, they will not affect the sampling operation.
[0021] In use, first inject the cleaning solution into the storage tank 3 through the inlet pipe 30. When sampling, the water pump 31 can be started to inject the cleaning solution into the sampling cylinder 1 through the elastic water guide pipe 32, which can initially clean the inside of the sampling cylinder 1. If further cleaning is required, the air pump 41 can be started to suck the waste liquid into the waste liquid tank 4 through the elastic water guide pipe 42. The waste liquid is discharged from the outlet pipe 40 to avoid the waste liquid adhering to the inside of the sampling cylinder 1 and being difficult to clean. The groove 201 of the limiting plate 24 can stabilize the hand, and the one-way channel avoids liquid backflow, improving sampling and processing efficiency.
[0022] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.
Claims
1. An immune cell detection sampling device, comprising a sampling tube (1) and a tube cover (2) threadedly connected to the opening end of the sampling tube (1), wherein a sampling head (11) is embedded at the bottom end of the sampling tube (1), a piston rod (21) is slidably connected through the top end of the tube cover (2), a piston (22) is fixedly connected to the bottom end of the piston rod (21), and a pressing plate (23) is fixedly connected to the top end of the piston rod (21); Its features are: Limiting plates (24) are fixedly connected to the upper ends of both sides of the outer wall of the cylinder cover (2). A support plate (25) is fixedly connected to the lower end of the outer wall of the cylinder cover (2). A liquid storage tank (3) is fixedly connected to the top of one side of the support plate (25). A water pump (31) is fixedly connected to the top of the liquid storage tank (3). An elastic water guide pipe (32) is fixedly connected to the output end of the water pump (31). A waste liquid tank (4) is fixedly connected to the top of the support plate (25). An air pump (41) is fixedly connected to the top of the waste liquid tank (4). An elastic liquid guide pipe (42) is fixedly connected to the output end of the air pump (41). Both the elastic liquid guide pipe (42) and the elastic water guide pipe (32) extend to the bottom of the piston (22).
2. The immune cell detection and sampling device according to claim 1, characterized in that: The upper part of the outer wall of the cylinder cover (2) is provided with grooves, and the sampling cylinder (1) and the cylinder cover (2) are made of transparent material.
3. The immune cell detection and sampling device according to claim 1, characterized in that: Both the elastic liquid guide tube (42) and the elastic water guide tube (32) are movably connected to the top of the cylinder cover (2), and both the elastic liquid guide tube (42) and the elastic water guide tube (32) are unidirectional channels.
4. The immune cell detection and sampling device according to claim 1, characterized in that: The bottom of each limiting plate (24) is fixedly connected with an abutment groove (201).
5. The immune cell detection and sampling device according to claim 1, characterized in that: The liquid storage tank (3) has an inlet pipe (30) embedded on one side of its top, and the waste liquid tank (4) has an outlet pipe (40) embedded at its lower end.