A device for detecting the flowability of a belly-banded tablet

Abstract

The utility model discloses a device for detecting the flowability of umbilically-applied tablets, which comprises a box capable of controlling temperature and / or humidity and a sample plate for the umbilically-applied tablets to flow thereon, the sample plate being arranged inside the box and having an inclined plane or a plane with adjustable gradient. The utility model has the beneficial effect that the flowability of the umbilically-applied tablets is detected, the melting degree when the umbilically-applied tablets are applied to the human body is corresponded, the subsequent process research and actual application time can be guided, the human and time costs of large-scale human application test are saved, and the operation and data management are facilitated.

Description

Technical Field

[0001] This utility model relates to the field of pharmaceutical or material testing, and in particular to a device for testing the flowability of umbilical patch tablets. Background Technology

[0002] Umbilical patches are topical tablets that work by being applied to the navel (Shenque acupoint). The fluidity of the patch is a crucial factor affecting its efficacy. The faster the patch melts, the wider the spread of the medicated liquid, potentially staining clothing and impacting the user experience. Conversely, poor melting of the patch hinders drug release, thus affecting efficacy. Currently, methods for detecting the fluidity of umbilical patches are limited, relying on manual observation. There are currently no instruments on the market to test the melting effect of the medicated patch after application, lacking automated and intelligent detection methods. Utility Model Content

[0003] In view of the shortcomings of the prior art, the technical problem to be solved by this utility model is to provide a device for rapidly detecting the flowability of umbilical patch tablets and corresponding to the melting of the tablets when applied to the human body, thereby guiding process research or application time.

[0004] To achieve the above objectives, the technical solution adopted by this utility model is as follows:

[0005] An apparatus for detecting the flowability of umbilical cord patches includes a chamber capable of controlling temperature and / or humidity and a sample plate for the umbilical cord patch to flow on; the sample plate is disposed inside the chamber and has an inclined plane or a plane with an adjustable inclination.

[0006] Furthermore, the device for detecting the flowability of the umbilical patch tablet also includes a sample plate tilt adjustment component; the sample plate tilt adjustment component includes a sample plate vertical adjustment component and a sample plate horizontal adjustment component, the sample plate vertical adjustment component is used to adjust the vertical position of the first edge of the sample plate in the box, and the sample plate horizontal adjustment component is used to adjust the vertical position of the second edge of the sample plate in the box, the first edge and the second edge are respectively located on opposite sides of the sample plate, and the position of the first edge is higher than that of the second edge.

[0007] Furthermore, the sample plate horizontal adjustment assembly includes a base plate and a sample plate fixing assembly. The sample plate fixing assembly adjusts the tilt angle of the sample plate by fixing the position of the second edge of the sample plate on the base plate. The sample plate vertical adjustment assembly is formed by the vertical inner wall of the box 1, and the first edge of the sample plate rests on it. When the second edge moves horizontally on the base plate, the first edge slides along the vertical inner wall of the box.

[0008] Furthermore, one or more sample cells are provided on the sample plate near the first edge, and a sample flow start line is provided on the side of the sample cell near the second edge of the sample plate to facilitate uniform measurement of sample flow length; the first edge and the second edge are located on opposite sides of the sample plate, and the position of the first edge is higher than that of the second edge.

[0009] Furthermore, the sample plate may or may not have scale lines.

[0010] Furthermore, the device for detecting the flowability of the umbilical patch includes an observation screen and a door switch handle.

[0011] Furthermore, the observation screen is an interactive terminal touch screen, and the temperature and humidity inside the enclosure are set via the interactive terminal touch screen.

[0012] Furthermore, the device for detecting the flowability of the patch tablets also includes an optical sensing module for tracking and measuring the flow length of the sample and / or a data processing module for recording and processing data.

[0013] Furthermore, the sample plate is made of a smooth, transparent sheet material.

[0014] Furthermore, the sample plate is made of glass or plastic.

[0015] Furthermore, the number of sample cells is selected from 3, 4, 5, 6, 7, 8, 9 or 10.

[0016] This utility model has the following advantages:

[0017] Compared with the prior art, the beneficial effects of this utility model are as follows: by detecting the fluidity of the umbilical patch tablet and corresponding it to the degree of melting when applied to the human body, this utility model can guide subsequent process research and actual application time, save manpower and time costs for large-scale human application experiments, and facilitate operation and data management. Attached Figure Description

[0018] Figure 1 This is a schematic diagram of the external structure of the device of this utility model;

[0019] Figure 2 This is a schematic diagram of the internal structure of the device of this utility model;

[0020] Figure 3 This is a plan view of the sample plate of this utility model;

[0021] Figure 4 The graph shows the change in flowability length of the patch tablet sample over storage time.

[0022] In the figure, 1-box body; 2-observation screen; 3-box door handle; 4-sample plate tilt adjustment assembly; 41-base plate; 42-sample plate fixing assembly; 43-sample plate vertical adjustment assembly; 44-sample plate horizontal adjustment assembly; 45-first edge; 46-second edge; 5-sample plate; 6-sample flow start line; 7-sample cell. Detailed Implementation

[0023] The present invention will be further described below with reference to specific embodiments. It should be understood that these embodiments are for illustrative purposes only and are not intended to limit the scope of the present invention.

[0024] Example

[0025] A device for detecting the flowability of umbilical patch tablets, such as Figure 1-3 As shown, the device includes a chamber 1 capable of controlling temperature and / or humidity and a sample plate 5 on which umbilical patch tablets flow; the sample plate 5 is disposed inside the chamber 1 and has an inclined plane or a plane with an adjustable inclination. The device for detecting the flowability of umbilical patch tablets also includes a sample plate inclination adjustment assembly 4, which includes a sample plate vertical adjustment assembly 43 and a sample plate horizontal adjustment assembly 44. The sample plate vertical adjustment assembly 43 is used to adjust the vertical position of the first edge 45 of the sample plate 5 in the chamber, and the sample plate horizontal adjustment assembly 44 is used to adjust the vertical position of the second edge 46 of the sample plate 5 in the chamber 1. The first edge 45 and the second edge 46 are located on opposite sides of the sample plate 5, and the position of the first edge 45 is higher than that of the second edge 46. The sample plate horizontal adjustment assembly 44 includes a base plate 41 and a sample plate fixing assembly 42. The sample plate fixing assembly 42 adjusts the tilt angle of the sample plate 5 by fixing the position of the second edge 46 of the sample plate 5 on the base plate 41. The sample plate vertical adjustment assembly 43 is formed by the vertical inner wall of the housing 1, and the first edge 45 of the sample plate 5 rests on it. When the second edge 46 moves horizontally on the base plate 41, the first edge 45 slides along the vertical inner wall of the housing 1. One or more sample pools 7 are also provided on the sample plate 5 near the first edge 45. A sample flow start line 6 is provided on the side of the sample pool 7 near the second edge 46 of the sample plate 5 to facilitate uniform measurement of the sample flow length. The device for detecting the flowability of the umbilical patch tablets also includes an observation screen 2, a door switch handle 3, an optical sensing module for tracking and measuring the sample flow length, and / or a data processing module for recording and processing data. The observation screen 2 is an interactive terminal touch screen, and the temperature and humidity inside the housing 1 are set through the interactive terminal touch screen.

[0026] 1. Screening of Liquidity Experimental Conditions

[0027] Umbilical cord patches with a shelf life of 36 months were selected for testing. Fluidity tests were conducted on patches stored for 1 and 36 months, respectively, to determine the fluidity test conditions. The goal was to ensure that all patches stored for the aforementioned periods exhibited fluidity, with significant differences in fluidity. Key factors considered included temperature and the tilt angle of the sample plate 5. The temperature inside the chamber 1 was set via an interactive touchscreen. The tilt angle of the sample plate 5 was set by moving the sample plate fixing assembly 42 on the base plate 41. Since the first edge of the sample plate 5 rests against the vertical inner wall of the chamber 1, changing the horizontal position of the second edge on the base plate 41 causes the first edge to move along the vertical inner wall of the chamber 1, thus changing the tilt angle of the sample plate 5. Specific testing conditions are shown in the table below (the height mentioned in the table is the vertical height of the first edge 45 from the base plate 41, and the tilt angle is the angle between the sample plate 5 and the base plate 41). The sample plate used in the experiment was 50 cm long. Table 1. Liquidity Experimental Conditions high 10cm 15cm 20cm 25cm The calculated tilt angle is approximately 11.5° 17.5° 23.6° 30°

[0028] The experimental conditions that achieved the strongest flowability of umbilical patch tablets after one month of storage and the initial flowability of umbilical patch tablets after 36 months of storage were a temperature of 44℃ and a height of 20cm. These conditions can be used for subsequent actual tests on the flowability of umbilical patch tablets.

[0029] 2. Flowability test of umbilical patch tablets

[0030] Multiple flowability experiments were conducted on umbilical cord patches with different storage periods (0, 1, 2, 3, 6, 9, 12, 15, 18, 24, and 36 months) to observe the flowability results. The width and flow time of sample cell 7 were set, the umbilical cord patch was placed in sample cell 7, and then placed in chamber 1 with the chamber door immediately closed. Temperature and humidity were set via the interactive terminal touchscreen, and the experiment was started. The flow length of the umbilical cord patch after melting was tracked by an optical sensing module, and the initial melting time was recorded by a data processing module.

[0031] Experimental results are as follows Figure 4 As shown, the fluidity of the umbilical patch tablets decreased with prolonged storage time, and the fluidity change was greatest in the first three months.

[0032] Umbilical patches with different storage periods were applied to human bodies, and their melting performance was observed. The results of human application were compared with the test results for the same storage period. The results are shown in Table 2: Table 2. Experimental results of umbilical patch tablets at different storage periods Melting performance of the patch test Spread across the entire page Smaller than the entire page The tablets all melted, with very little leakage. The pills did not dissolve Liquidity test results Beyond the edge of the sample plate 28cm 4-20cm 1cm Is it suitable to apply the patch? It is not suitable for application and requires a longer period of stabilization. The application effect needs further improvement and stabilization. Depending on the flow length, it can be stabilized for 5 days to 1 month. It has moderate fluidity, provides good application, and does not overflow after application. The application effect is poor; the sample does not melt after application.

[0033] Freshly produced umbilical patch tablets have the highest fluidity. During human application experiments, the medication spread across the entire dressing surface and even seeped through the adhesive tape. After half an hour of fluidity testing, the medication had flowed beyond the edge of the sample plate.

[0034] The umbilical patch tablets with a shelf life of one month exhibited slightly weaker flowability; during human application experiments, the medication spread did not extend beyond the surface of the dressing. The flowability test lasted for half an hour, with an average flow length of 28 cm.

[0035] When umbilical patch tablets with a shelf life of 3-24 months are applied, the medication melts completely with minimal leakage. A flowability test conducted for half an hour showed a flow length of approximately 4-20 cm.

[0036] During human application experiments, occasional instances of undissolved medication were observed in umbilical patch tablets with a shelf life of 36 months. In the flowability test, flow was minimal after half an hour, with an average length of approximately 1 cm.

[0037] In summary, the flowability results of the umbilical patch correspond to the results of the human application experiment. By detecting the flowability of the umbilical patch using this device, we can preliminarily determine the melting performance of the umbilical patch when applied to the human body. Finally, we can infer whether the experimental sample is suitable for human application based on the flowability results.

[0038] 3. Data Analysis

[0039] The data processing module analyzes the data and determines the melting status of the umbilical patch tablets when applied to the human body based on the flow length and melting time of the experimental sample. A report is generated, and the data can be exported and the report can be printed on the interactive terminal touch screen.

[0040] The above-disclosed embodiments are merely preferred embodiments of the present invention and are not intended to limit the present invention in any other way. Those skilled in the art will understand that the present invention is not limited to the various specific embodiments. For those skilled in the art, improvements or modifications may be made within the scope of the present invention without departing from its technical principles, and the various technical features mentioned throughout the specification can be combined with each other. All such improvements or modifications should be covered within the protection scope of the present invention.

Claims

1. A device for detecting the flowability of umbilical patch tablets, characterized in that: It includes a chamber (1) capable of controlling temperature and / or humidity and a sample plate (5) on which umbilical tablets flow; the sample plate (5) is disposed inside the chamber (1) and has an inclined plane or a plane with an adjustable inclination.

2. The apparatus for detecting the flowability of umbilical patch tablets according to claim 1, characterized in that: The device for detecting the flowability of the umbilical patch tablet further includes a sample plate tilt adjustment assembly (4); the sample plate tilt adjustment assembly (4) includes a sample plate vertical adjustment assembly (43) and a sample plate horizontal adjustment assembly (44). The sample plate vertical adjustment assembly (43) is used to adjust the vertical position of the first edge (45) of the sample plate (5) in the housing (1), and the sample plate horizontal adjustment assembly (44) is used to adjust the horizontal position of the second edge (46) of the sample plate (5) in the housing (1). The first edge (45) and the second edge (46) are located on opposite sides of the sample plate (5), and the position of the first edge (45) is higher than that of the second edge (46).

3. The apparatus for detecting the flowability of umbilical patch tablets according to claim 2, characterized in that: The sample plate horizontal adjustment assembly (44) includes a base plate (41) and a sample plate fixing assembly (42). The sample plate fixing assembly (42) adjusts the tilt angle of the sample plate (5) by fixing the position of the second edge (46) of the sample plate (5) on the base plate (41). The sample plate vertical adjustment assembly (43) is formed by the vertical inner wall of the box (1). The first edge (45) of the sample plate (5) rests on it. When the second edge (46) moves horizontally on the base plate (41), the first edge (45) slides along the vertical inner wall of the box (1).

4. The apparatus for detecting the flowability of umbilical patch tablets according to claim 1, characterized in that: One or more sample pools (7) are provided on the sample plate (5) near the first edge (45). A sample flow start line (6) is provided on the side of the sample pool (7) near the second edge (46) of the sample plate (5). The first edge (45) and the second edge (46) are located on opposite sides of the sample plate (5), and the position of the first edge (45) is higher than that of the second edge (46).

5. The apparatus for detecting the flowability of umbilical patch tablets according to claim 1, characterized in that: The sample plate (5) may or may not have scale lines.

6. The apparatus for detecting the flowability of umbilical patch tablets according to claim 1, characterized in that: The device for detecting the flowability of the umbilical patch tablets also includes an observation screen (2) and a door handle (3).

7. The apparatus for detecting the flowability of umbilical patch tablets according to claim 6, characterized in that: The observation screen (2) is an interactive terminal touch screen, and the temperature and / or humidity inside the box (1) can be set through the interactive terminal touch screen.

8. The apparatus for detecting the flowability of umbilical patch tablets according to claim 1, characterized in that: The device for detecting the flowability of the umbilical patch tablets also includes an optical sensing module for tracking and measuring the flow length of the sample and / or a data processing module for recording and processing data.

9. The apparatus for detecting the flowability of umbilical patch tablets according to claim 1, characterized in that: The sample plate (5) is made of a smooth and transparent sheet material.

10. The apparatus for detecting the flowability of umbilical patch tablets according to claim 9, characterized in that: The sample plate (5) is made of glass or plastic.

11. The apparatus for detecting the flowability of umbilical patch tablets according to claim 4, characterized in that: The number of sample pools (7) is selected from 3, 4, 5, 6, 7, 8, 9 or 10.

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