A sample analyzer
Patent Information
- Application Number
- CN202521431130.0
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-07-08
- Publication Date
- 2026-09-25
- Estimated Expiration
- 2035-07-08
AI Technical Summary
此外,仪器还需额外容纳龙门架支撑结构的物理占位,最终使得其外形尺寸远大于各轴独立运动所需空间的简单累加
[0016]综上所述,本实用新型的一种样本分析仪,采用旋转驱动组件驱动移液组件、或移液组件和检测组件进行旋转运动,同时独立设置直线驱动组件驱动第一试样放置装置和试剂提供装置作直线运动。这种设计使得直线运动轨迹与旋转运动轨迹在竖直方向上的投影部分重合,从而保证移液组件可以实现取液、滴液功能,及保证检测组件可以实现检测功能。此设计,在结构上,用YZR(即直线运动、Z轴运动和旋转运动)坐标定位位移系统取代XYZ坐标定位位移系统,大幅减小仪器整体体积,尤其适合空间有限的实验室环境;在操作效率上,旋转驱动组件的应用有效提升了仪器的行程利用率,且旋转驱动组件与Z轴驱动组件快速定位移液组件和检测组件的同时,直线驱动组件可及时调整第一试样放置装置和试剂提供装置位置,检测流程更顺畅,效率得以明显提升;在定位精度上,旋转驱动组件与直线驱动组件独立设置,避免了两者组装的累计误差,提高了系统定位精度,保障了分析结果的准确性。
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Figure CN224803070U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of sample analysis technology, and in particular to a sample analyzer. Background Technology
[0002] Existing sample analyzers generally employ a gantry structure combined with an XYZ coordinate positioning and displacement system to achieve core operations such as sample collection, reagent dispensing, and detection. This sample analyzer uses three sets of linear motion modules to achieve three-dimensional spatial positioning of the pipetting or detection device, and each axis requires an independent range of motion: when the Y-axis module moves along the X-axis, the working area must simultaneously accommodate the entire movement trajectory of the Y-axis module and the displacement space of the X-axis module. This results in the overall size of the equipment exhibiting a linear superposition effect of the ranges of motion for each axis, i.e., effective X-axis travel + effective Y-axis travel + Z-axis lifting height. Furthermore, the instrument also needs to accommodate the physical space occupied by the gantry support structure, ultimately making its overall dimensions much larger than the simple sum of the spaces required for the independent movement of each axis.
[0003] This type of sample analyzer has significant limitations in the following scenarios: when the device needs to be deployed on a space-constrained workbench, such as a short and narrow workbench, the excessively large size of the device will seriously affect its placement adaptability and fail to meet the user's need for a compact instrument.
[0004] Therefore, there is an urgent need to develop a sample analyzer to solve the problem. Utility Model Content
[0005] Therefore, the purpose of this utility model is to provide a sample analyzer that effectively improves the compactness of the product structure and extends the product's service life.
[0006] To solve the above-mentioned technical problems, the technical solution adopted by this utility model is as follows: In a first aspect, a sample analyzer includes: A stage for placing the first sample placement device and reagent supply device at intervals; A linear drive assembly is used to drive the first sample placement device to reciprocate between an initial position and a drop position along a first direction, and / or drive the reagent supply device to reciprocate between an initial position and a liquid collection position along a first direction; A pipetting assembly is used to transfer the reagent solution in the reagent supply device to the first sample placement device to obtain the test sample; The detection component is used for the detection of the sample to be tested. A rotary drive assembly is provided with a rotating shaft. The pipetting assembly is connected to the rotating shaft. The rotary drive assembly is used to drive the rotating shaft to rotate, thereby driving the pipetting assembly to rotate to the liquid collection position or the liquid dispensing position.
[0007] Furthermore, the detection component includes a first detection mechanism, which is connected to the rotating shaft and can rotate with the rotating shaft to be placed above the first sample placement device to perform detection operations on the sample to be tested.
[0008] Furthermore, the detection component includes a Z1 drive mechanism and a first detection mechanism. The Z1 drive mechanism is connected to the rotating shaft and is used to drive the first detection mechanism to move up and down.
[0009] Furthermore, the Z1 drive mechanism includes a third slide rail, a third slide block, and a second drive member. The third slide rail is vertically arranged on the rotating shaft. The first detection mechanism is fixed on the third slide block. The second drive member is used to drive the third slide block to slide back and forth along the direction of the third slide rail. The second driving component includes a second driving motor and a second driving rod. The second driving motor is fixed to either the third slide or the first detection mechanism. The second driving rod is connected to the output end of the second driving motor. The second driving rod is a lead screw structure. A threaded groove is provided in the rotating shaft. The second driving rod is connected to the rotating shaft by a thread. When the second driving motor drives the second driving rod to rotate, the second driving rod moves back and forth in the up-down direction, thereby driving the third slide connected to the second driving motor to move back and forth in the Z-axis direction.
[0010] Furthermore, a guide mechanism is provided between the rotating shaft and the third slide, the guide mechanism including a matching guide groove and a guide block; When the guide groove is disposed on the third slide, the guide block is disposed on the rotating shaft; when the guide groove is disposed on the rotating shaft, the guide block is disposed on the third slide.
[0011] Furthermore, the detection assembly includes a first detection mechanism and a second detection mechanism; the stage is also used to place a second sample placement device; the linear drive assembly is also used to drive the second sample placement device to reciprocate between an initial position and a dropping position along a first direction; the pipetting assembly is also used to transfer the reagent solution in the reagent supply device to the second sample placement device to obtain a test sample; the first detection mechanism and the second detection mechanism are respectively used to perform detection operations on the test samples on the first sample placement device and the second sample placement device.
[0012] Furthermore, it also includes a light source for providing the light source required for testing the sample.
[0013] Furthermore, the pipetting assembly includes a Z2 drive mechanism and a reagent transfer mechanism. The Z2 drive mechanism is disposed on the rotating shaft and is used to drive the reagent transfer mechanism to move up and down.
[0014] Furthermore, the rotary drive assembly also includes a fourth drive member, which is used to drive the rotating shaft to rotate; the fourth drive member includes a fourth drive motor and a drive wheel, a rotating wheel is provided at the bottom end of the rotating shaft, the drive wheel is connected to the output shaft of the fourth drive motor, and the drive wheel and the rotating wheel are connected by a synchronous belt.
[0015] Furthermore, the linear drive assembly includes a first drive member and a slide rail member. The first drive member is used to drive the platform to slide back and forth along the direction of the slide rail member. A through slot is provided in the middle region of the platform. The rotating shaft passes through the through slot of the platform. The design length of the through slot along the first direction is not less than the running displacement of the platform. The slide rail component includes a first slide rail and a second slide rail, which are respectively disposed on both sides of the rotating shaft portion; the stage includes a first slide block and a second slide block connected to each other; the sample placement device is disposed on one of the first slide block and the second slide block; the reagent supply device is disposed on the other of the first slide block and the second slide block; and the first driving member is used to drive the first slide block to slide back and forth along the direction of the first slide rail and to drive the second slide block to slide back and forth along the direction of the second slide rail. The linear drive assembly further includes a base, on which a fixed seat is provided. The first slide rail is disposed on the fixed seat along a first direction, and the second slide rail is fixed on the base along the first direction. A fixing groove is provided on the fixed seat. The first drive component includes a first drive motor, a first drive rod, and a guide rail rack. The first drive motor is fixed on the first slide and connected to the first drive rod. A gear is provided on the first drive rod. The first slide rail and the guide rail rack are disposed parallel to each other in the fixing groove, and the gear meshes with the guide rail rack.
[0016] In summary, this utility model discloses a sample analyzer that employs a rotary drive assembly to drive the pipetting assembly, or the pipetting assembly and the detection assembly, to rotate. Simultaneously, an independently configured linear drive assembly drives the first sample placement device and the reagent supply device to perform linear motion. This design ensures that the vertical projections of the linear motion trajectory and the rotational motion trajectory coincide, thereby guaranteeing that the pipetting assembly can perform liquid collection and dispensing functions, and that the detection assembly can perform its detection function. Structurally, this design replaces the XYZ coordinate positioning system with a YZR (i.e., linear motion, Z-axis motion, and rotational motion) coordinate positioning system, significantly reducing the overall size of the instrument, making it particularly suitable for space-constrained laboratory environments. In terms of operational efficiency, the application of the rotary drive assembly effectively improves the instrument's stroke utilization rate. Furthermore, while the rotary drive assembly and the Z-axis drive assembly quickly position the pipetting assembly and the detection assembly, the linear drive assembly can promptly adjust the positions of the first sample placement device and the reagent supply device, resulting in a smoother detection process and significantly improved efficiency. Regarding positioning accuracy, the independent configuration of the rotary drive assembly and the linear drive assembly avoids the cumulative error from their assembly, improving the system's positioning accuracy and ensuring the accuracy of the analytical results. Attached Figure Description
[0017] Figure 1 This is a first-view structural schematic diagram of a sample analyzer according to the present invention; Figure 2 This is a schematic diagram of the second perspective of a sample analyzer according to the present invention; Figure 3 This is a schematic diagram of the sample analyzer corresponding to the first detection mechanism of this utility model, which is fixed on the rotating shaft by the Z1 drive mechanism. Figure 4 This is a schematic diagram of the combination of a linear drive component and a stage according to the present invention; Figure 5 This is a schematic diagram of the combination of a linear drive component and a stage from another perspective of this utility model; Figure 6 This is a schematic diagram of a combination of a pipetting assembly and a detection assembly according to the present invention; Figure 7 This is a schematic diagram of the structure of the pipetting assembly of this utility model; Figure 8 This is a schematic diagram of the running trajectory of the detection component of this utility model when it is rotated and combined with the pipetting component, the first sample placement device, and the reagent supply device. Figure 9 This is a schematic diagram of the running trajectory of the detection component of this utility model when it is in a stationary state, combined with the pipetting component, the first sample placement device, and the reagent supply device; Figure 10This is a schematic diagram of the sample analyzer corresponding to the first detection mechanism of this utility model being directly fixed on the rotating shaft. Figure 11 This is a schematic diagram of the sample analyzer corresponding to the first detection mechanism of this utility model, which is fixed on the base by a fixing frame. Figure 12 This is a schematic diagram of the sample analyzer in which the first detection mechanism of this utility model is set on the rotating shaft and the second detection mechanism is fixed on the base. Figure 13 This is a schematic diagram of the structure of the first embodiment corresponding to the rotary drive component in other embodiments of this utility model; Figure 14 This is a schematic diagram of the structure of the second embodiment corresponding to the rotary drive component in other embodiments of this utility model; Figure 15 This is a schematic diagram of the structure of the third embodiment corresponding to the rotary drive component in other embodiments of this utility model; Figure 16 This is a schematic diagram of the straight plate-shaped structure corresponding to the rotating shaft in other embodiments of this utility model.
[0018] Explanation of key component symbols: 100. Stage; 101. Through slot; 110. First slide; 111. Hole; 120. Second slide; 130. Fixing plate; 200. Linear drive assembly; 210. First drive component; 211. First drive motor; 212. First drive rod; 213. Guide rail rack; 214. Gear; 220. Slide rail component; 221. First slide rail; 222. Second slide rail; 230. Base; 231. Through-hole; 232. Arc groove; 240. Fixing seat; 241. Fixing groove; 300. Pipetting assembly; 310. Z2 drive mechanism; 311. Connecting plate; 312. Fourth slide rail; 313. Fourth slide block; 314. Third drive component; 3141. Third drive motor; 3142. Third drive rod; 320. Reagent transfer mechanism; 321. Tip; 400. Detection component; 410. Z1 drive mechanism; 411. Third slide rail; 412. Third slide block; 413. Second drive component; 4131. Second drive motor; 4132. Second drive rod; 420. First detection mechanism; 421. Lens assembly; 430. Second detection mechanism; 500. Rotary drive assembly; 510. Shaft; 520. Fourth drive component; 521. Fourth drive motor; 522. Drive pulley; 523. Rotating pulley; 524. Synchronous belt; 530. Base column; 540. Fifth drive motor; 541. First planetary gear; 542. First sun gear; 550. Sixth drive motor; 551. Drive wheel; 552. Fixed pulley; 553. Transmission belt; 561. Second planetary gear; 562. Gear ring; 600. Light source components; 701. First sample placement device; 702. Reagent supply device; 7021. Mounting base; 7022. Reagent tank; 703. Second sample placement device; 801. Guide groove section; 802. Guide block. Detailed Implementation
[0019] The technical solution of this utility model will now be clearly and completely described with reference to the accompanying drawings. Obviously, the described embodiments are only some, not all, of the embodiments of this utility model. Based on the embodiments of this utility model, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this utility model.
[0020] In the description of this utility model, it should be noted that the terms "center," "upper," "lower," "left," "right," "vertical," "horizontal," "inner," and "outer," etc., indicating the orientation or positional relationship, are based on the orientation or positional relationship shown in the accompanying drawings and are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and should not be construed as indicating or implying relative importance.
[0021] In the description of this utility model, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "joining" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model based on the specific circumstances.
[0022] Example 1 like Figures 1 to 8As shown, this utility model provides a sample analyzer that can be applied to a blood cell analyzer. The sample analyzer includes a stage 100, a linear drive assembly 200, a pipetting assembly 300, a detection assembly 400, and a rotary drive assembly 500. The stage 100 is used to space a first sample placement device 701 and a reagent supply device 702. The stage 100 is mounted on the linear drive assembly 200, which drives the first sample placement device 701 to reciprocate between its initial position and the dispensing position along a first direction, and / or drives the reagent supply device 702 to reciprocate between its initial position and the dispensing position along a first direction. The pipetting assembly 300 transfers the reagent solution from the reagent supply device 702 to the first sample placement device 701 to obtain the sample to be tested. The detection assembly 400 is used to transfer the reagent solution from the reagent supply device 702 to the first sample placement device 701 to obtain the sample to be tested. The test sample is subjected to detection operation; the rotary drive assembly 500 is provided with a rotating shaft 510, and the pipetting assembly is connected to the rotating shaft. The rotary drive assembly 500 is used to drive the rotating shaft 510 to rotate, thereby driving the pipetting assembly 300 to rotate to the liquid collection position or the liquid dispensing position; wherein, the first direction can be designed as the direction of the line connecting the position of the sample analyzer display interface and the position of the operator, that is, the Y-axis direction, to adapt to the operator's operating habits; or the first direction can also be designed as the X-axis direction as needed; in this embodiment, the first direction is preferably the Y-axis direction. The pipetting assembly 300 and / or the detection assembly can be directly set on the rotating shaft 510, or it can be connected to the rotating shaft through a support structure. The pipetting assembly 300 and / or the detection assembly is fixed on the support structure. When the rotating shaft rotates, it drives the support structure to rotate, thereby enabling the pipetting assembly 300 and / or the detection assembly to perform rotation operation.
[0023] In this invention, the circular motion trajectory formed by the vertical projection of the rotation path of the pipetting assembly 300 and the linear motion trajectory formed by the vertical projection of the reagent supply device 702 after its movement have a second intersection point. The circular motion trajectory formed by the vertical projection of the rotation path of the pipetting assembly 300 and the linear motion trajectory formed by the vertical projection of the first sample placement device 701 after its movement have a first intersection point. The second intersection point and the first intersection point correspond to the vertical projection points of the liquid collection position and the liquid drop position, respectively. By independently configuring the linear drive component 200 and the rotary drive component 500, a separate operating mode is formed where the linear drive component 200 drives the stage 100 in linear motion, and the rotary drive component 500 drives the pipetting component 300 and / or the detection component 400 in rotational motion. This ensures that the vertical projections of the linear drive component 200 driving the stage 100 in linear motion and the rotary drive component 500 driving the pipetting component 300 and / or the detection component 400 in rotational motion overlap, achieving composite functionality without the need for superimposed drive components. This design eliminates the need for the linear drive component 200 on top of the rotary drive component 500, avoiding the problem of increased rotation radius and thus increased rotational motion coverage when the rotary drive component 500 drives the linear drive component 200 in rotational motion; it also eliminates the need for the rotary drive component 500 on top of the linear drive component 200, avoiding the problem of increased linear motion coverage when the linear drive component 200 drives the rotary drive component 500 in linear motion. This invention effectively improves the compactness of the sample analyzer structure and reduces the space occupied by the instrument.
[0024] When the sample analyzer of this utility model performs testing, the pipetting assembly 300 first rotates to the liquid collection position to perform liquid collection operation, then rotates to the drop position to deliver the reagent solution in the reagent supply device 702 to the first sample placement device 701, and finally cooperates with the detection assembly 400 to perform the detection operation on the sample to be tested on the first sample placement device 701.
[0025] Specifically, driven by the rotary drive assembly 500, the pipetting assembly 300 is rotated from its initial position to the liquid-collecting position. Simultaneously, driven by the linear drive assembly 200, the reagent supply device 702 is moved from its initial position to the liquid-collecting position, allowing the pipetting assembly 300 to collect the reagent solution from the reagent supply device 702. Then, driven by the rotary drive assembly 500, the pipetting assembly 300 is rotated to the dispensing position. Simultaneously, driven by the linear drive assembly 200, the first sample placement device 701 is moved to the dispensing position, allowing the pipetting assembly 300 to dispense the reagent solution from the reagent supply device 702 onto the first sample placement device 701. This process is repeated once or multiple times as needed to obtain the test sample on the first sample placement device 701. Finally, the detection assembly 400 performs a detection operation on the test sample on the first sample placement device 701 below it.
[0026] When the detection component 400 rotates along with the rotating shaft 510, it rotates to a position above the first sample placement device 701 under the drive of the rotation drive component 500 to perform a detection operation on the sample to be tested. When the detection component 400 does not need to be fixed to the rotating shaft 510, it remains stationary. After fixing the detection component 400 in a preset position, the linear drive component 200 moves the first sample placement device 701 below the detection component 400, and then the detection component 400 performs a detection operation on the sample to be tested on the first sample placement device 701 below it. Alternatively, when the first sample placement device 701 is below the detection component 400, the detection component 400 directly detects the sample to be tested on the first sample placement device 701. It can also, according to the detection requirements of the sample, have the linear drive component 200 drive the first sample placement device 701 to perform a linear reciprocating motion, thereby enabling the detection component 400 to perform a complete scan of the sample to be tested on the first sample placement device 701 to obtain accurate detection results.
[0027] This invention places the pipetting assembly 300 and / or the detection assembly 400 on the rotary drive assembly 500 and rotates under the drive of the rotary drive assembly 500. Simultaneously, the first sample placement device 701 and the reagent supply device 702 are placed on the stage 100 and move linearly along a first direction under the drive of the linear drive assembly 200. By independently arranging the linear drive assembly 200 and the rotary drive assembly 500, the linear motion of the stage 100 and the rotational motion of the pipetting assembly 300 and / or the detection assembly 400 operate independently. This avoids placing the linear drive assembly 200 on the rotary drive assembly 500 or vice versa, effectively improving the structural compactness of the sample analyzer and reducing the space occupied by the instrument. Furthermore, by independently configuring the linear drive component 200 and the rotary drive component 500, the linear and rotary motions can operate independently and in parallel. When the rotary drive component 500 performs pipetting and / or detection actions, the linear drive component 200 can synchronously adjust the position of the stage 100, making the detection process smoother, shortening the detection cycle, and significantly improving efficiency. In addition, independently configuring the linear drive component 200 and the rotary drive component 500 can also avoid the problem of increased cumulative error in the horizontal direction caused by assembling the linear drive component 200 and the rotary drive component 500 together, thereby ensuring the detection accuracy of the sample analyzer of this utility model. In this embodiment, the detection component 400 can be a microscope detection module, a fluorescence detection module, or a colloidal gold detection module, etc., and the first sample placement device 701 can be a counting plate or a test strip, etc.
[0028] like Figure 8As shown, since the pipetting assembly 300 and / or the detection module 400 can perform circular motion around the rotating shaft 510 under the drive of the rotary drive assembly 500, the reagent supply device 702 and the first sample placement device 701 perform linear motion along the Y-axis under the drive of the linear drive assembly 200. When the rotary drive assembly 500 drives the pipetting assembly 300 to the dropping position, the circular motion trajectory Q1 formed by the projection of the movement path of the pipetting assembly 300 in the vertical direction and the linear motion trajectory L1 formed by the projection of the movement path of the first sample placement device 701 in the vertical direction have two first intersection points A1 and A2. When the pipetting assembly 300 rotates to either of the two first intersection points A1 and A2, the reagent liquid drawn by the pipetting assembly 300 will drip onto the first sample placement device 701. When the rotation drive assembly 500 drives the pipetting assembly 300 to rotate to the liquid collection position, the circular motion trajectory Q1 formed by the vertical projection of the movement path of the pipetting assembly 300 and the linear motion trajectory L2 formed by the vertical projection of the movement path of the reagent supply device 702 have two second intersection points B1 and B2. The liquid collection operation can be realized by rotating the pipetting assembly 300 to either of the two second intersection points B1 and B2.
[0029] In addition, since the reagent supply device 702 needs to provide multiple reagent solutions for the first sample placement device 701, the reagent supply device 702 includes a mounting base 7021 on which a reagent kit can be placed. The reagent kit is provided with multiple reagent slots 7022, each containing a corresponding type of reagent solution for the pipetting assembly 300 to perform liquid dispensing operations. In this embodiment, when the pipetting assembly 300 rotates to either of the two second intersection points B1 or B2, the reagent slot 7022 corresponding to the reagent solution to be dispensed moves to the corresponding second intersection point B1 or B2 under the drive of the linear drive assembly 200. There are two locations, which facilitates the pipetting assembly 300 to take the reagent solution from the reagent tank 7022. In other embodiments, some reagent tanks 7022 in the reagent supply device 702 can be empty. The pipetting assembly 300 can transfer the reagent solution from other reagent tanks 7022 to the empty reagent tanks 7022 for mixing to obtain a mixed reagent solution. The reagent tank 7022 corresponding to the mixed reagent solution moves to the corresponding second intersection point B1 or B2 under the drive of the linear drive assembly 200. Then, the pipetting assembly 300 picks up the mixed reagent solution and transfers it to the first sample placement device 701.
[0030] In one embodiment, the linear drive assembly 200 includes a first drive member 210 and a slide rail member 220. The first drive member 210 drives the stage 100 to slide back and forth along the slide rail member 220. A through groove 101 is provided in the middle region of the stage 100. In this embodiment, the rotating shaft 510 passes through the through groove 101 of the stage 100. The designed length of the through groove 101 along the first direction is not less than the running displacement of the stage 100. The first sample placement device 701 and the reagent supply device 702 are respectively arranged on both sides of the through groove 101 of the stage 100. The pipetting assembly 300 and / or the detection assembly 400 are driven by the rotary drive assembly. Driven by the rotating component 500, the rotating shaft 510 makes a circular motion, which can more quickly rotate the pipetting component 300 to the liquid collection position for liquid collection and to the liquid dispensing position for liquid dispensing. In this embodiment, the rotating shaft 510 of the rotary drive component 500 is placed in the through groove 101 of the stage 100. In the vertical direction, the movement trajectory of the pipetting component 300 and / or the detection component 400 can be limited to the space occupied by the linear drive component 200 driving the stage 100 to make a linear motion. This effectively improves the structural compactness of the sample analyzer of this utility model and reduces the space occupied by the instrument.
[0031] In one embodiment, the slide rail 220 includes a first slide rail 221 and a second slide rail 222, which are respectively disposed on both sides of the rotating shaft portion 510; the stage 100 includes a first slide block 110 and a second slide block 120 connected to each other, which are respectively disposed on both sides of the through groove 101; a first sample placement device 701 is disposed on one of the first slide block 110 and the second slide block 120; and a reagent supply device 702 is disposed on the other of the first slide block 110 and the second slide block 120. The driving component 210 is used to drive the first slide block 110 to slide back and forth along the first slide rail 221 and to drive the second slide block 120 to slide back and forth along the second slide rail 222. By placing the rotating shaft 510 of the rotary drive assembly 500 in the through groove 101 of the stage 100, the movement trajectory of the pipetting assembly 300 and / or the detection assembly 400 in the vertical direction can be limited to the space occupied by the linear drive assembly 200 driving the stage 100 to make linear movements, which effectively improves the structural compactness of the sample analyzer of this utility model and reduces the space occupied by the instrument.
[0032] Furthermore, the linear drive assembly 200 also includes a base 230, on which a first slide rail 221 and a second slide rail 222 are disposed. A through-hole 231 is provided at the front end of the base 230, through which the rotating shaft 510 passes. A fixed seat 240 is provided at the rear end of the base 230. The first slide rail 221 is disposed on the fixed seat 240 along a first direction, and the second slide rail 222 is fixed to the base 230 along the first direction. The first slide block 110 and the second slide block 120 are connected by a fixing plate 130, thereby enabling the first slide block 110 and the second slide block 120 to move synchronously along the first direction under the drive of the first drive member 210. The device moves back and forth. In this embodiment, the fixing plate 130 and the second slide 120 can be integrally formed. The first slide 110, the second slide 120 and the fixing plate 130 are combined to form a stage 100 with a slot 101 structure. By placing the rotating shaft 510 of the rotary drive assembly 500 in the slot 101 of the stage 100, the movement trajectory of the pipetting assembly 300 and / or the detection assembly 400 in the vertical direction can be limited to the space occupied by the linear drive assembly 200 driving the stage 100 to make linear movements. This effectively improves the structural compactness of the sample analyzer of this utility model and reduces the space occupied by the instrument.
[0033] Specifically, the fixed base 240 has a fixed groove 241. The first driving component 210 includes a first driving motor 211, a first driving rod 212, and a guide rail rack 213. The first driving motor 211 is fixed on the first slide 110 and is connected to the first driving rod 212. A gear 214 is provided on the first driving rod 212. The first slide rail 221 and the guide rail rack 213 are arranged parallel to each other in the fixed groove 241. The gear 214 and the guide rail rack 213 are meshed. The first driving motor 211 drives the first driving rod 212 to rotate, and the gear 214 rotates synchronously, so that the gear 214 moves back and forth along the direction of the guide rail rack 213, thereby causing the first driving motor 211 to move back and forth along the direction of the guide rail rack 213. Since the first driving motor 211 is fixed on the first slide 110, the effect of the first slide 110 moving back and forth along the first slide rail 221 is achieved.
[0034] In this embodiment, the first slide rail 221 and the second slide rail 222 are arranged in parallel. Since the second slide block 120 is fixedly connected to the first slide block 110 through the fixing plate 130, when the first slide block 110 moves back and forth along the first slide rail 221, it will synchronously drive the second slide block 120 to move back and forth along the direction of the second slide rail 222, so as to achieve the effect of the first slide block 110 and the second slide block 120 moving along the first direction.
[0035] Alternatively, the first drive unit 210 can also be designed as a motor and lead screw structure, with the lead screw connected to the first slide 110 or the second slide 120 by a threaded connection. The motor drives the lead screw to rotate, causing the first slide 110 or the second slide 120 to slide back and forth in the first direction. This drive structure is known technology and will not be described in detail here.
[0036] Example 2 Based on Embodiment 1, when the detection component rotates with the rotation of the shaft, the detection component can be implemented using the following structure.
[0037] like Figure 8 As shown, when the sample to be tested on the first sample placement device 701 needs to be tested, the rotary drive component 500 drives the detection component 400 to rotate to the detection area corresponding to the first sample placement device 701. Simultaneously, the linear drive component 200 drives the first sample placement device 701 to perform a linear reciprocating motion, thereby enabling the detection component 400 to perform a complete scanning operation on the sample to be tested on the first sample placement device 701 to obtain accurate detection results. The circular motion trajectory Q2 formed by the vertical projection of the movement path of the detection component 400 and the linear motion trajectory L1 formed by the vertical projection of the movement path of the first sample placement device 701 have a third intersection point C, which is located within the vertical projection of the detection area. Furthermore, the width d of the detection area is not less than the width d2 of the sample to be tested. The detection angle width of the detection component 400 is d1, and the width of the sample to be tested is d2. When d = d1 ≥ d2, the rotary drive component 500 only needs to rotate the detection component 400 to the third intersection point C and then cooperate with the linear drive component 200 to drive the first sample placement device 701 to make linear motion to achieve a complete scanning operation of the sample to be tested. When d1 < d2, the rotary drive component 500 rotates the detection component 400 to a certain distance d3 and d4 on the left and right sides of the third intersection point C as needed to increase the final detection width of the detection component 400, so that d = d1 + d3 + d4 ≥ d2. During this period, every time the detection component 400 rotates to a position in the detection area, it cooperates with the linear drive component 200 to drive the first sample placement device 701 to make linear motion. After multiple scanning operations, a complete scanning operation of the sample to be tested is achieved.
[0038] Specifically, such as Figure 10As shown, the detection component 400 includes a first detection mechanism 420, which is connected to the rotating shaft 510. In this embodiment, the first detection mechanism 420 is fixedly mounted on the rotating shaft 510 and / or the pipetting assembly 300. After the first detection mechanism 420 rotates above the first sample placement device 701 as the rotating shaft 510 rotates, the sample to be tested on the first detection mechanism 420 can be directly detected. In this embodiment, the first detection mechanism 420 is a detection module that does not require zooming during use, such as a fluorescence detection module or a colloidal gold detection module.
[0039] or, like Figure 3 , Figure 6 and Figure 7 As shown, the detection component 400 includes a Z1 drive mechanism 410 and a first detection mechanism 420. The Z1 drive mechanism 410 is connected to the rotating shaft 510. In this embodiment, the Z1 drive mechanism 410 is mounted on the rotating shaft 510 and is used to drive the first detection mechanism 420 to move up and down. In this embodiment, a lens assembly 421 is mounted on the first detection mechanism 420. The Z1 drive mechanism 410 drives the first detection mechanism 420 to move up and down, thereby adjusting the distance between the lens assembly 421 on the first detection mechanism 420 and the first sample placement device 701, realizing the zoom operation of the lens assembly 421, and facilitating the observation of the test sample on the first sample placement device 701 by the lens assembly 421.
[0040] Specifically, the Z1 drive mechanism 410 includes a third slide rail 411, a third slide block 412, and a second drive member 413. The third slide rail 411 is vertically mounted on the rotating shaft 510. The first detection mechanism 420 is fixed on the third slide block 412. The second drive member 413 is used to drive the third slide block 412 to slide back and forth along the direction of the third slide rail 411.
[0041] Further, the second driving component 413 includes a second driving motor 4131 and a second driving rod 4132. The second driving motor 4131 is fixed to one of the third slide block 412 or the first detection mechanism 420. The second driving rod 4132 is connected to the output end of the second driving motor 4131. The second driving rod 4132 is a lead screw structure. In this embodiment, the rotating shaft 510 is a cylindrical structure, and a threaded groove is provided at the upper end of the rotating shaft 510. The second driving rod 4132 is connected to the rotating shaft 510 by a thread. When the second drive motor 4131 drives the second drive rod 4132 to rotate, the second drive rod 4132 moves back and forth in the up and down direction, thereby driving the second drive motor 4131 to move back and forth in the Z-axis direction. Since the second drive motor 4131 is fixedly connected to the third slide 412 and the first detection mechanism 420, the effect of the third slide 412 and the first detection mechanism 420 moving back and forth in the Z-axis direction is achieved, which facilitates the first detection mechanism 420 to detect the sample to be tested on the first sample placement device 701.
[0042] like Figure 6 and Figure 7 As shown, in one embodiment, a guide mechanism is provided between the rotating shaft 510 and the third slide 412 to make the third slide 412 move more stably along the Z-axis. Specifically, the guide mechanism includes a guide groove 801 and a guide block 802 that are matched. When the guide groove 801 is provided on the third slide 412, the guide block 802 is provided on the rotating shaft 510; when the guide groove 801 is provided on the rotating shaft 510, the guide block 802 is provided on the third slide 412. In this embodiment, the installation positions of the guide groove 801 and the guide block 802 can be adapted to the rotating shaft 510 and the third slide 412 as needed, which will not be elaborated here.
[0043] Example 3 Based on Embodiment 1, when the detection component does not need to be fixed on the rotating shaft, the detection component is in a fixed state, and the detection component can be implemented using the following structure.
[0044] like Figure 11 As shown, the detection component 400 includes a first detection mechanism 420. A fixing frame (not shown) is provided on the base 230. The first detection mechanism 420 is fixed on the fixing frame. When the test sample on the first sample placement device 701 moves to below the first detection mechanism 420, the first detection mechanism 420 can directly detect the test sample. In this embodiment, the first detection mechanism 420 is a detection module that does not require zooming during use, such as a fluorescence detection module or a colloidal gold detection module.
[0045] or, The detection assembly 400 includes a Z1 drive mechanism and a first detection mechanism 420. A fixed frame is provided on the base 230, and the first detection mechanism 420 is fixed on the fixed frame. The Z1 drive mechanism is provided on the fixed frame and is used to drive the first detection mechanism 420 to move up and down. The first detection mechanism 420 is provided with a lens assembly (not shown). The Z1 drive mechanism drives the first detection mechanism 420 to move up and down, thereby adjusting the distance between the lens assembly on the first detection mechanism 420 and the first sample placement device 701, realizing the zoom operation of the lens assembly, and facilitating the observation of the test sample on the first sample placement device 701 by the lens assembly.
[0046] Example 4 Example 4 can be extended based on Example 2 or Example 3. In this Example 4, Example 2 will be used as the basis for the explanation.
[0047] like Figures 1 to 7 As shown, the detection assembly 400 also includes a second detection mechanism 430. When the second detection mechanism 430 is present, the stage 100 is also used to place the second sample placement device 703, the linear drive assembly 200 is also used to drive the second sample placement device 703 to reciprocate between the initial position and the drop position along the first direction, and the pipetting assembly 300 is also used to transfer the reagent liquid in the reagent supply device 702 to the second sample placement device 703 to obtain the test sample. The first detection mechanism 420 and the second detection mechanism 430 are respectively used to perform detection operations on the test samples on the first sample placement device 701 and the second sample placement device 703.
[0048] The second detection mechanism 430 can be fixed on the rotating shaft 510, the pipetting assembly 300, or the first detection mechanism 420 as needed, and rotates with the rotating shaft 510 to rotate the second detection mechanism 430 to the second sample placement device 703, and perform detection operations on the sample to be tested on the second sample placement device 703. The second sample placement device 703 can be a counting plate or a test strip, etc. The position of the second sample placement device 703 on the stage 100 can be different from the placement position of the first sample placement device 701 and the reagent supply device 702, or it can replace the placement position of the first sample placement device 701. That is, when only the second sample placement device 703 needs to be detected, the second sample placement device 703 can be placed in the original position of the first sample placement device 701 on the stage 100, or other suitable positions can be selected on the stage 100 to place the second sample placement device 703, so that the sample analyzer of this utility model has the effect of multiple detection functions.
[0049] In addition, the stage 100 is provided with a reagent placement slot and at least two sample placement slots. The reagent placement slot is used to place the reagent supply device 702, and the sample placement slot is used to place the first sample placement device 701 and / or the second sample placement device 703. This allows the stage 100 to simultaneously place multiple first sample placement devices 701 and / or multiple second sample placement devices 703. Placing multiple first sample placement devices 701 or multiple second sample placement devices 703 on the stage 100 can correspond to the same testing needs of different patients. Placing first sample placement devices 701 and second sample placement devices 703 on the stage 100 can correspond to different testing needs of the same patient, or different testing needs of different patients. This allows the same sample analyzer to acquire multiple test results simultaneously, thereby effectively improving the testing efficiency of the sample analyzer. In this embodiment, the first sample placement device 701 is disposed in the sample placement slot on the first slide 110, and the second sample placement device 703 is disposed in the sample placement slot on the second slide 120.
[0050] Alternatively, such as Figure 12 As shown, the second detection mechanism 430 can also be fixedly mounted above the stage 100, meaning it does not need to rotate with the rotation of the rotating shaft 510. In conjunction with the linear drive assembly 200, the second sample placement device 703 is moved to directly below the second detection mechanism 430, allowing the second detection mechanism 430 to perform detection operations on the sample to be tested on the second sample placement device 703. Specifically, by setting a fixing frame on the base 230 to fix the second detection mechanism 430, the effect of fixing the second detection mechanism 430 above the stage 100 can be achieved.
[0051] In one embodiment, the pipetting assembly 300 includes a Z2 drive mechanism 310 and a reagent transfer mechanism 320. The Z2 drive mechanism 310 is mounted on the rotating shaft 510 and is used to drive the reagent transfer mechanism 320 to move up and down. The reagent transfer mechanism 320 has a tip 321 at its end to facilitate the aspiration of reagent liquid from the reagent tank 7022. The reagent transfer mechanism 320 has a suction and discharge assembly (not shown). The reagent transfer mechanism 320 uses the suction and discharge assembly in conjunction with the tip 321 to aspirate or discharge the reagent liquid from the reagent tank 7022. Under the drive of the rotary drive assembly 500 and the Z2 axis drive mechanism 310, the pipetting assembly 300 transfers the reagent liquid in the reagent supply device 702 to the first sample placement device 701 or the second sample placement device 703. The suction and discharge assembly is known technology and will not be described in detail here.
[0052] Furthermore, the Z2 drive mechanism 310 includes a connecting plate 311, a fourth slide rail 312, a fourth slide block 313, and a third drive member 314. The connecting plate 311 is fixed on the rotating shaft 510, the fourth slide rail 312 is fixed on the connecting plate 311 in the vertical direction, the reagent transfer mechanism 320 is fixed on the fourth slide block 313, and the third drive member 314 is used to drive the fourth slide block 313 to slide back and forth along the direction of the fourth slide rail 312, thereby realizing the effect of the reagent transfer mechanism 320 moving in the Z-axis direction. This facilitates the tip head 321 to descend into the reagent tank 7022 and draw reagent liquid from it, and also facilitates the tip head 321 to rise above the stage 100 and then move to the first sample placement device 701 or the second sample placement device 703 for dripping operation.
[0053] Specifically, the third driving component 314 includes a third driving motor 3141 and a third driving rod 3142. The third driving motor 3141 is fixed on the connecting plate 311, and the third driving rod 3142 is a lead screw structure. The third driving rod 3142 is connected to the fourth slide block 313 by a thread. When the third driving motor 3141 drives the third driving rod 3142 to rotate, the fourth slide block 313 moves back and forth along the direction of the fourth slide rail 312, thereby realizing the effect of the reagent transfer mechanism 320 moving along the Z-axis direction. This facilitates the tip head 321 to descend into the reagent tank 7022 and draw reagent liquid from it, or facilitates the tip head 321 to rise above the stage 100 and then move to the first sample placement device 701 or the second sample placement device 703 for dripping operation.
[0054] In one embodiment, the rotary drive assembly 500 further includes a fourth drive member 520, which is used to drive the rotating shaft 510 to rotate. Specifically, the fourth drive member 520 includes a fourth drive motor 521 and a drive wheel 522. One end of the rotating shaft 510 is provided with a rotating wheel 523. The fourth drive motor 521 is fixed on the base 230. The drive wheel 522 is connected to the output shaft of the fourth drive motor 521. The drive wheel 522 and the rotating wheel 523 are connected by a synchronous belt 524. When the fourth drive motor 521 drives the drive wheel 522 to rotate, the synchronous belt 524 drives the rotating wheel 523 to rotate as well, thereby realizing the rotation operation of the rotating shaft 510.
[0055] Furthermore, a support bearing is provided in the through-hole 231 of the base 230, and the rotating shaft 510 is locked on the base 230 through the support bearing. The drive wheel 522 and the rotating wheel 523 are arranged below the base 230 so as to improve the space utilization in the Z-axis direction when assembling the sample analyzer of this utility model.
[0056] Alternatively, the fourth drive unit 520 can also be designed as a motor-gear transmission structure, with a drive gear connected to the output shaft of the motor, and the outer edge of the drive wheel designed as a transmission gear structure. Through the meshing design of the drive gear and the transmission gear, the drive wheel 522 drives the rotating shaft 510 to rotate.
[0057] like Figure 13 and Figure 16 As shown, in other embodiments, a base column 530 is provided on the base 230, and the base column 530 passes through the through slot 101 of the stage 100. The rotating shaft 510 is mounted on the base column 530 via a bearing. In this embodiment, the rotating shaft 510 has a disc or straight plate structure and is located at the upper end of the base column 530. The rotary drive assembly 500 is used to drive the rotating shaft 510 to rotate about the base column 530 as an axis. The pipetting assembly 300 and / or the detection assembly 400 are mounted on the rotating shaft 510. Specifically, the rotary drive assembly 500 also includes a fifth drive motor 540. The fifth drive motor 540 is fixed on the rotating shaft 510. The output end of the fifth drive motor 540 is connected to the first planetary gear 541. The base column 530 is provided with the first sun gear 542 below the rotating shaft 510. The first planetary gear 541 and the first sun gear 542 are meshed together. When the fifth drive motor 540 drives the first planetary gear 541 to rotate, the first planetary gear 541 will rotate around the first sun gear 542, thereby driving the fifth drive motor 540 and the rotating shaft 510 to rotate simultaneously, and then driving the pipetting assembly 300 and / or the detection assembly 400 to rotate with the rotation of the rotating shaft 510.
[0058] like Figure 14 and Figure 16As shown, alternatively, a base column 530 is provided on the base 230, and the base column 530 passes through the through slot 101 of the stage 100. The rotating shaft 510 is mounted on the base column 530 via a bearing. In this embodiment, the rotating shaft 510 has a disc or straight plate structure and is located at the upper end of the base column 530. The rotary drive assembly 500 is used to drive the rotating shaft 510 to rotate about the base column 530 as an axis. The pipetting assembly 300 and / or the detection assembly 400 are mounted on the rotating shaft 510. Specifically, the rotary drive assembly 500 also includes a sixth drive motor 550, which is fixed. On the rotating shaft 510, the output end of the sixth drive motor 550 is connected to a drive wheel 551, and a fixed wheel 552 is provided on the base column 530. The fixed wheel 552 is located below the rotating shaft 510. The drive wheel 551 and the fixed wheel 552 are connected by a transmission belt 553. When the sixth drive motor 550 drives the drive wheel 551 to rotate, the drive wheel 551 will rotate around the fixed wheel 552 under the restriction of the transmission belt 553, thereby driving the sixth drive motor 550 and the rotating shaft 510 to rotate simultaneously, and then driving the pipetting assembly 300 and / or the detection assembly 400 to rotate with the rotation of the rotating shaft 510.
[0059] like Figure 15 As shown, alternatively, a base column 530 is provided on the base 230, the base column 530 is disposed through the through groove 101 of the stage 100, and the rotating shaft 510 is disposed on the base column 530 by a bearing. In this embodiment, the rotating shaft 510 has a disc structure and is disposed at the upper end of the base column 530. The rotary drive assembly 500 is used to drive the rotating shaft 510 to rotate about the base column 530 as an axis. The pipetting assembly 300 and / or the detection assembly 400 are disposed on the rotating shaft 510. Specifically, the rotary drive assembly 500 also includes a seventh The seventh drive motor is fixed on the base column 530. The output end of the seventh drive motor is connected to the second planetary gear 561. A gear ring 562 is provided below the shaft part 510 outside the base column 530. The second planetary gear 561 and the gear ring 562 are meshed. When the seventh drive motor drives the second planetary gear 561 to rotate, the gear ring 562 will rotate around the base column 530 as the axis, thereby driving the shaft part 510 to rotate at the same time, and then driving the pipetting assembly 300 and / or the detection assembly 400 to rotate with the rotation of the shaft part 510.
[0060] In one embodiment, the sample analyzer of this utility model further includes a light source 600 for providing the light source required for the detection of the sample to be tested. The light source 600 can be positioned above or below the stage 100 as needed, and can rotate together with the rotating shaft 510. In this embodiment, the light source 600 is positioned below the stage 100. Specifically, the light source 600 is positioned below the first slide 110, which is used to place the first sample placement device 701. The first slide 110 has a hollow hole 111 at the location where the first sample placement device 701 is placed. The light emitted by the light source 600 illuminates the first sample placement device 701 through the hollow hole 111 to provide the light source required for the detection of the first detection mechanism 420, so as to better detect the sample to be tested on the first sample placement device 701.
[0061] Furthermore, the light source 600 is positioned directly below the first detection mechanism 420. The light source 600 is fixed on the rotating wheel 523 or the rotating shaft 510. The rotating wheel 523 drives the rotating shaft 510 to rotate, which in turn drives the light source 600 to rotate, so that the light source 600 and the first detection mechanism 420 rotate synchronously to the first sample placement device 701 and provide the light source required for the test sample. In order to better enable the light source 600 to provide light, an arc-shaped groove 232 is provided on the base 230 to adapt to the motion trajectory formed when the light source 600 rotates, so that the light emitted by the light source 600 can shine onto the first sample placement device 701 without obstruction.
[0062] Alternatively, the light source 600 can be directly fixed on the base 230. The light emitted by the light source 600 is diffused in the form of scattering to provide the light source required for testing the sample over a wider range.
[0063] Example 5 Please see Figures 1 to 12According to the sample analyzer of the present invention, the present invention provides a method for implementing the sample analyzer. The stage 100, linear drive assembly 200, pipetting assembly 300, detection assembly 400, and rotary drive assembly 500 involved in this method have the same technical features as those described in the above-mentioned sample analyzer embodiment and can produce the same technical effects. The method for implementing the sample analyzer of the present invention separates the linear drive assembly 200 and the rotary drive assembly 500, allowing the linear motion of the stage 100 and the rotary motion of the pipetting assembly 300 and / or detection assembly 400 to operate independently. This ensures that the vertical projection of the linear motion range of the stage 100 driven by the linear drive assembly 200 coincides with the vertical projection of the rotary motion range of the pipetting assembly 300 and / or detection assembly 400 driven by the rotary drive assembly 500. Therefore, it is not necessary to mount the linear drive assembly 200 on the rotary drive assembly 500 or vice versa. This design avoids increasing the coverage area of either the rotary drive assembly 500 driving the linear drive assembly 200 in a rotary motion or the linear drive assembly 200 driving the rotary drive assembly 500 in a linear motion, thus effectively improving the structural compactness of the sample analyzer and reducing the space occupied by the instrument. Furthermore, by independently setting up the linear drive assembly 200 and the rotary drive assembly 500, the linear and rotary motions can operate independently and in parallel. When the rotary drive assembly 500 performs pipetting and / or detection actions, the linear drive assembly 200 can synchronously adjust the position of the stage 100, resulting in a smoother detection process, a shorter detection cycle, and a significant improvement in efficiency.
[0064] The present invention discloses a method for implementing a sample analyzer, comprising the following steps: S1. Place the first sample placement device 701 and the reagent supply device 702 on the stage 100; S2. The reagent supply device 702, driven by the linear drive assembly 200, and the pipetting assembly 300, driven by the rotary drive assembly 500, move to the liquid collection position respectively. The pipetting assembly 300 performs a liquid collection operation on the reagent supply device 702. The linear drive assembly 200 drives the stage 100 to move linearly along the first direction, so that the vertical projection of the movement path of the reagent supply device 702 forms a linear motion trajectory L2. The rotary drive assembly 500 drives the pipetting assembly 300 to rotate, so that the vertical projection of the movement path of the pipetting assembly 300 forms a circular motion trajectory Q1. The circular motion trajectory Q1 and the linear motion trajectory L2 have two second intersection points B1 and B2. Either of the two second intersection points B1 and B2 corresponds to the vertical projection of the liquid collection position. When the two second intersection points B1 and B2 coincide, the circular motion trajectory Q1 and the linear motion trajectory L2 are tangent. S3. The first sample placement device 701, driven by the linear drive assembly 200, and the pipetting assembly 300, driven by the rotary drive assembly 500, move to the dropping position respectively. The pipetting assembly 300 delivers the aspirated reagent liquid to the first sample placement device 701 for dropping. The linear drive assembly 200 drives the stage 100 to move linearly along the first direction, so that the projection of the movement path of the first sample placement device 701 in the vertical direction forms a linear motion trajectory L1. The rotary drive assembly 500 drives the pipetting assembly 300 to rotate, so that the projection of the movement path of the pipetting assembly 300 in the vertical direction forms a circular motion trajectory Q1. The circular motion trajectory Q1 and the linear motion trajectory L1 have two first intersection points A1 and A2. Either of the two first intersection points A1 and A2 corresponds to the projection of the dropping position in the vertical direction. When the two first intersection points A1 and A2 coincide, the circular motion trajectory Q1 is tangent to the linear motion trajectory L1. S4. After repeating steps S2 and S3 once or multiple times as needed for testing, the sample to be tested is obtained on the first sample placement device 701. S5. Move the first sample placement device 701 to below the detection area corresponding to the detection component 400 to perform a detection operation on the sample to be tested on the first sample placement device 701.
[0065] The following explanation uses the detection component corresponding to Example 2 as an example. Figure 8As shown, driven by the rotary drive component 500, the detection component 400 rotates to the detection area corresponding to the first sample placement device 701 to perform detection operations on the test sample on the first sample placement device 701. Alternatively, according to the detection requirements of the test sample, after the detection component 400 rotates to the detection area corresponding to the first sample placement device 701, the linear drive component 200 will drive the first sample placement device 701 to perform linear reciprocating motion, thereby enabling the detection component 400 to perform a complete scanning operation on the test sample on the first sample placement device 701 to obtain accurate detection results. In addition, the circular motion trajectory Q2 formed by the projection of the motion path of the detection component 400 in the vertical direction and the linear motion trajectory L1 formed by the projection of the motion path of the first sample placement device 701 in the vertical direction have a third intersection point C, which is located within the vertical projection of the detection area corresponding to the first sample placement device 701.
[0066] Specifically, the width d of the detection area is not less than the width d2 of the sample to be tested. The detection viewing angle width of the detection component 400 is d1, and the width of the sample to be tested is d2. When d = d1 ≥ d2, the rotary drive component 500 only needs to rotate the detection component 400 to the third intersection point C, and then the linear drive component 200 will drive the first sample placement device 701 to make linear motion, thus realizing the complete scanning operation of the sample to be tested. When d1 < d2, the rotary drive component 500, as needed, rotates the detection component 400 to a certain distance d3 and d4 on the left and right sides of the third intersection point C, respectively, to increase the final detection width of the detection component 400, so that d = d1 + d3 + d4 ≥ d2. During this period, the detection component 400 rotates... When the device moves to a position within the detection area, the linear drive component 200 will drive the first sample placement device 701 to move linearly. After multiple scanning operations, a complete scanning operation of the sample to be tested can be achieved. Among them, the distances d3 and d4 are the distances between the projection of the detection component 400 in the vertical direction and the third intersection point C along the width direction of the sample to be tested, and d3 and d4 are less than d1 / 2. When the circular motion trajectory Q2 intersects the linear motion trajectory L1, there are two third intersection points C. At this time, the detection operation of the sample to be tested can be achieved as long as either of the two third intersection points is within the projection of the detection area in the vertical direction. When the circular motion trajectory Q2 is tangent to the linear motion trajectory L1, there is one third intersection point C.
[0067] The following explanation uses the detection component corresponding to Embodiment 3 as an example. Figure 9As shown, since the detection component 400 is stationary in the vertical direction, to avoid the installation position of the detection component 400 being on the movement path of the pipetting component 300, the installation position of the detection component 400 can be designed to be outside or inside the circumference formed by the movement path of the pipetting component 300. Preferably, the installation position of the detection component 400 is outside the circumference formed by the movement path of the pipetting component 300. In this case, the installation position of the detection component 400 is required to be: outside the circumference formed by the movement path of the pipetting component 300, and the projection point D of the detection component 400 in the vertical direction is on the straight line trajectory L1 formed by the projection of the movement path of the first sample placement device 701 in the vertical direction. After the sample to be tested is obtained on the first sample placement device 701, the linear drive component 200 will drive the first sample placement device 701 to move the sample to the projection point D, thereby realizing the detection operation of the detection component 400 on the sample to be tested; or, according to the detection requirements of the sample to be tested, the linear drive component 200 can drive the first sample placement device 701 to perform linear reciprocating motion, thereby enabling the detection component 400 to perform a complete scanning operation on the sample to be tested on the first sample placement device 701 to obtain accurate detection results.
[0068] In summary, this utility model discloses a sample analyzer that employs a rotary drive assembly to drive the pipetting assembly, or the pipetting assembly and the detection assembly, to rotate. Simultaneously, an independently configured linear drive assembly drives the first sample placement device and the reagent supply device to perform linear motion. This design ensures that the vertical projections of the linear motion trajectory and the rotational motion trajectory coincide, thereby guaranteeing that the pipetting assembly can perform liquid collection and dispensing functions, and that the detection assembly can perform its detection function. Structurally, this design replaces the XYZ coordinate positioning system with a YZR (i.e., linear motion, Z-axis motion, and rotational motion) coordinate positioning system, significantly reducing the overall size of the instrument, making it particularly suitable for space-constrained laboratory environments. In terms of operational efficiency, the application of the rotary drive assembly effectively improves the instrument's stroke utilization rate. Furthermore, while the rotary drive assembly and the Z-axis drive assembly quickly position the pipetting assembly and the detection assembly, the linear drive assembly can promptly adjust the positions of the first sample placement device and the reagent supply device, resulting in a smoother detection process and significantly improved efficiency. Regarding positioning accuracy, the independent configuration of the rotary drive assembly and the linear drive assembly avoids the cumulative error from their assembly, improving the system's positioning accuracy and ensuring the accuracy of the analytical results.
[0069] The above-described embodiments are merely illustrative of several implementations of this utility model, and while the descriptions are specific and detailed, they should not be construed as limiting the scope of this utility model. It should be noted that those skilled in the art can make various modifications and improvements without departing from the concept of this utility model, and these all fall within the protection scope of this utility model. Therefore, the protection scope of this utility model should be determined by the appended claims.
Claims
1. A sample analyzer, characterized in that, include: A stage for placing the first sample placement device and reagent supply device at intervals; A linear drive assembly is used to drive the first sample placement device to reciprocate between an initial position and a drop position along a first direction, and / or drive the reagent supply device to reciprocate between an initial position and a liquid collection position along a first direction; A pipetting assembly is used to transfer the reagent solution in the reagent supply device to the first sample placement device to obtain the test sample; The detection component is used for the detection of the sample to be tested. A rotary drive assembly is provided with a rotating shaft. The pipetting assembly is connected to the rotating shaft. The rotary drive assembly is used to drive the rotating shaft to rotate, thereby driving the pipetting assembly to rotate to the liquid collection position or the liquid dispensing position.
2. The sample analyzer according to claim 1, characterized in that, The detection assembly includes a first detection mechanism, which is connected to the rotating shaft and can rotate with the rotating shaft to be placed above the first sample placement device to perform detection on the sample to be tested.
3. The sample analyzer according to claim 1, characterized in that, The detection component includes a Z1 drive mechanism and a first detection mechanism. The Z1 drive mechanism is connected to the rotating shaft and is used to drive the first detection mechanism to move up and down.
4. A sample analyzer according to claim 3, characterized in that, The Z1 drive mechanism includes a third slide rail, a third slide block and a second drive member. The third slide rail is arranged vertically on the rotating shaft. The first detection mechanism is fixed on the third slide block. The second drive member is used to drive the third slide block to slide back and forth along the direction of the third slide rail. The second driving component includes a second driving motor and a second driving rod. The second driving motor is fixed to either the third slide or the first detection mechanism. The second driving rod is connected to the output end of the second driving motor. The second driving rod is a lead screw structure. A threaded groove is provided on the rotating shaft. The second driving rod is connected to the rotating shaft by a thread. When the second driving motor drives the second driving rod to rotate, the second driving rod moves back and forth in the up-down direction, thereby driving the third slide connected to the second driving motor to move back and forth in the Z-axis direction.
5. A sample analyzer according to claim 4, characterized in that, A guide mechanism is provided between the rotating shaft and the third slide block. The guide mechanism includes a matching guide groove and a guide block. When the guide groove is disposed on the third slide, the guide block is disposed on the rotating shaft; when the guide groove is disposed on the rotating shaft, the guide block is disposed on the third slide.
6. A sample analyzer according to claim 1, characterized in that, The detection assembly includes a first detection mechanism and a second detection mechanism; the stage is also used to place a second sample placement device; the linear drive assembly is also used to drive the second sample placement device to reciprocate between an initial position and a drop position along a first direction; the pipetting assembly is also used to transfer the reagent solution in the reagent supply device to the second sample placement device to obtain a test sample; the first detection mechanism and the second detection mechanism are respectively used to perform detection operations on the test samples on the first sample placement device and the second sample placement device.
7. A sample analyzer according to claim 1, characterized in that, It also includes a light source for providing the light source required for testing the sample.
8. A sample analyzer according to claim 1, characterized in that, The pipetting assembly includes a Z2 drive mechanism and a reagent transfer mechanism. The Z2 drive mechanism is disposed on the rotating shaft and is used to drive the reagent transfer mechanism to move up and down.
9. A sample analyzer according to claim 1, characterized in that, The rotary drive assembly further includes a fourth drive component, which is used to drive the rotating shaft to rotate. The fourth drive component includes a fourth drive motor and a drive wheel. A rotating wheel is provided at the bottom end of the rotating shaft. The drive wheel is connected to the output shaft of the fourth drive motor. The drive wheel and the rotating wheel are connected by a synchronous belt.
10. A sample analyzer according to claim 1, characterized in that, The linear drive assembly includes a first drive component and a slide rail component. The first drive component is used to drive the platform to slide back and forth along the direction of the slide rail component. A through slot is provided in the middle region of the platform. The rotating shaft passes through the through slot of the platform. The design length of the through slot along the first direction is not less than the running displacement of the platform. The slide rail component includes a first slide rail and a second slide rail, which are respectively disposed on both sides of the rotating shaft portion; the stage includes a first slide block and a second slide block connected to each other; the sample placement device is disposed on one of the first slide block and the second slide block; the reagent supply device is disposed on the other of the first slide block and the second slide block; and the first driving member is used to drive the first slide block to slide back and forth along the direction of the first slide rail and to drive the second slide block to slide back and forth along the direction of the second slide rail. The linear drive assembly further includes a base, on which a fixed seat is provided. The first slide rail is disposed on the fixed seat along a first direction, and the second slide rail is fixed on the base along the first direction. A fixing groove is provided on the fixed seat. The first drive component includes a first drive motor, a first drive rod, and a guide rail rack. The first drive motor is fixed on the first slide and connected to the first drive rod. A gear is provided on the first drive rod. The first slide rail and the guide rail rack are disposed parallel to each other in the fixing groove, and the gear meshes with the guide rail rack.