Rodent periodontitis modeler

Abstract

The utility model discloses a kind of rodent periodontitis modeling devices, including tool main body, opening part and hold line part;Opening part and hold line part are separately arranged at the both ends of tool main body, opening part is used to be sleeved at the maxilla or mandible of animal, and the maxilla and mandible of animal are pried, so that the molar of animal leaks out;Hold line part has hold line groove, the groove width of hold line groove gradually increases from the direction of inside to outside notch.The utility model discloses a kind of rodent periodontitis modeling devices, the groove width of hold line groove gradually increases from inside to notch direction, can facilitate suture thread to rapidly escape from hold line groove, and smoothly place at tooth neck line, avoid damaging bone tissue and gum tissue, greatly improve periodontitis modeling efficiency and success rate.

Description

Technical Field

[0001] This utility model relates to the field of rodent periodontitis modeling technology, and in particular to a rodent periodontitis modeler. Background Technology

[0002] Periodontitis modeling is a technique that simulates the pathological processes of human periodontitis (such as gingival inflammation, periodontal pocket formation, and alveolar bone resorption) to construct periodontal tissue damage models in experimental animals. These models are widely used in research on the pathogenesis of periodontal disease, drug development, and evaluation of treatment methods. The silk suture ligation method is a commonly used non-bacterial inflammatory modeling method in periodontitis research. It mechanically obstructs the gingival sulcus, promotes natural plaque accumulation, and induces a host immune response and periodontal tissue destruction. This method is simple to operate, low in cost, and can simulate the natural pathogenesis of periodontitis, making it particularly suitable for studying the association between periodontitis and systemic diseases or screening anti-inflammatory drugs.

[0003] When using the suture ligation method for modeling, it is necessary to use modeling tools to tightly ligate the suture (silk thread) to the neck of the tooth. However, the existing modeling tools are not easy to remove the suture from the modeling tools, which greatly reduces the modeling efficiency. Moreover, removing the suture from the modeling tools will increase the force applied, but excessive force can easily cause damage to the animal's gingival tissue and micro-damage to the bone tissue, leading to modeling failure. Utility Model Content

[0004] This invention provides a rodent periodontitis modeler to overcome the above-mentioned problems.

[0005] To achieve the above objectives, the technical solution of this utility model is as follows:

[0006] A rodent periodontitis modeler includes a tool body, an opening, and a wire holding part;

[0007] The opening and the thread-holding part are respectively located at both ends of the tool body. The opening is used to fit over the upper or lower jaw of the animal and to open the upper and lower jaws of the animal so that the animal's molars are exposed.

[0008] The wire holding part has a wire holding groove, and the width of the wire holding groove gradually increases from the inside to the outside of the groove opening.

[0009] Furthermore, the inner sidewall of the wire holding groove extends obliquely from the inside to the outside, making the wire holding groove outwardly flared. The angle between the inner sidewall of the wire holding groove and the vertical direction is θ, where θ is 12°.

[0010] Furthermore, the outer wall of the wire-holding part is arc-shaped, which can fit against the lateral tooth surface of the animal's tooth.

[0011] Furthermore, the opening includes a concave groove at the end of the tool body and a pull wire at the opening of the concave groove.

[0012] Furthermore, the pull cord is a medical-grade nylon cord.

[0013] Furthermore, the tool body is provided with a handle portion, which is located between the opening portion and the wire holding portion.

[0014] Furthermore, the main body of the tool is made of nickel-titanium alloy.

[0015] The beneficial effects of this utility model are:

[0016] The rodent periodontitis modeling device disclosed in this utility model has a suture holding groove whose width gradually increases from the inside to the opening, which facilitates the rapid removal of the suture from the groove and its smooth placement at the cervical line of the tooth, avoiding damage to bone and gingival tissue, and greatly improving the efficiency and success rate of periodontitis modeling. Attached Figure Description

[0017] To more clearly illustrate the technical solutions in the embodiments of this utility model or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0018] Figure 1 This is a schematic diagram of a rodent periodontitis modeler disclosed in an embodiment of the present invention. Figure 1 ;

[0019] Figure 2 This is a schematic diagram of a rodent periodontitis modeler disclosed in an embodiment of the present invention. Figure 2 ;

[0020] Figure 3 This is a schematic diagram of the main view of a rodent periodontitis modeler disclosed in an embodiment of this utility model;

[0021] Figure 4 This is a front view schematic diagram of the wire-holding part of a rodent periodontitis modeler disclosed in an embodiment of this utility model;

[0022] Figure 5 This is a schematic diagram (during modeling) of a rodent periodontitis modeler disclosed in an embodiment of the present invention and the position of rodent molars;

[0023] Figure 6 This is a schematic diagram illustrating the modeling process of a rodent periodontitis modeler disclosed in an embodiment of the present invention, wherein... Figure 6 A is a schematic diagram of opening the mouse's mouth using the opening; Figure 6 B is a schematic diagram showing the position of the modeler relative to the molar when the suture is placed along the cervical line of the molar using this modeler;

[0024] Figure 6 C is a schematic diagram showing the position of the modeler relative to the molar, indicating that the suture line was placed on the cervical line on the other side of the molar using this modeler. Figure 6 D is a schematic diagram of the silk thread tied at the cervical line of the tooth.

[0025] In the diagram: 1. Tool body; 2. Opening; 21. Concave groove; 22. Pulling thread; 3. Thread holding part; 31. Thread holding groove; 4. Handle part; 5. Grinding teeth; 6. Suture thread. Detailed Implementation

[0026] To make the objectives, technical solutions, and advantages of the embodiments of this utility model clearer, the technical solutions of the embodiments of this utility model will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this utility model, not all embodiments. Based on the embodiments of this utility model, all other embodiments obtained by those skilled in the art without creative effort are within the protection scope of this utility model.

[0027] like Figure 1-3 The image shows a rodent periodontitis modeler provided in this embodiment, including a tool body 1, an opening 2, and a thread holding part 3;

[0028] The opening 2 and the thread-holding part 3 are respectively provided at both ends of the tool body 1. The opening 2 is used to fit over the upper or lower jaw of the animal and to open the upper and lower jaws of the animal so that the animal's molars are exposed.

[0029] The wire holding part 3 has a wire holding groove 31, and the width of the wire holding groove 31 gradually increases from the inner side to the outer side of the groove opening.

[0030] The rodent periodontitis modeling device disclosed in this utility model has a suture holding groove whose width gradually increases from the inside to the opening, which facilitates the rapid removal of the suture from the groove and its smooth placement at the cervical line of the tooth, avoiding damage to bone and gingival tissue, and greatly improving the efficiency and success rate of periodontitis modeling.

[0031] When the suture thread slides along the inclined plane, the combined effect of gravity and the inclined plane force allows the thread to slide out of the thread holding groove 31 quickly without much force. This avoids the problems of jamming or repeated dragging damage caused by the high friction of traditional vertical grooves, reducing the modeling time from 30 minutes to 4.8 minutes, improving efficiency by 83%, and increasing the success rate from 38% to 94%.

[0032] In a specific embodiment, such as Figure 4 As shown, the inner sidewall of the suture groove 31 extends obliquely from the inside to the outside, making the suture groove 31 outwardly flared. The angle between the inner sidewall of the suture groove 31 and the vertical direction is θ, which is 12°. Setting the angle of the inner wall of the suture groove 31 to 12° has the following advantages: First, it can increase the speed at which the suture is removed from the tool (suture groove 31); second, it can ensure that the suture contacts the tooth along the optimal path, reducing the damage of lateral forces to periodontal tissues; third, it optimizes the mechanical distribution, that is, it can disperse pressure and reduce local stress concentration. When the suture is subjected to external force in the suture groove 31, this inclined angle will decompose the pressure along the inclined plane into two components: one perpendicular to the tooth direction and the other horizontal. Compared with the traditional vertical groove wall, this inclined design avoids the pressure concentration at a certain point or small area where the suture contacts the suture groove 31, but disperses the pressure over a larger area, thereby reducing the pressure value per unit area, reducing the compression on periodontal tissues, and avoiding micro-damage to bone tissue, such as... Figure 5 The diagram shows the position of the periodontitis modeler, the suture, and the molar during the modeling process.

[0033] At the Animal Experiment Center of Dalian Medical University, this equipment was used to model 50 SD rats. The average modeling time was 4.8 minutes, the success rate was 94%, and the trauma rate was reduced from 19.7% to 2.6%.

[0034] In a specific embodiment, the outer wall of the wire-holding part 3 is arc-shaped, which can conform to the lateral tooth surface of the animal's tooth; the arc-shaped outer wall can adapt to the lateral curvature of the rodent's molar, and the arc-shaped outer wall forms a surface contact with the tooth surface, avoiding the sliding or positioning deviation caused by point contact in traditional straight-bar tools; such as Figure 6 As shown, if the molar side is relatively inclined and the gap between the teeth is large, the outer wall of the thread holding part 3 can be used to abut against the side of the molar for modeling operations. This allows the angle of the suture line entering the gap between the molars to be adjusted by finely adjusting the angle of this tool, which facilitates the smooth progress of the modeling operation.

[0035] In a specific embodiment, the opening 2 includes a concave groove 21 at the end of the tool body 1 and a pull wire 22 at the opening of the concave groove 21; the concave groove 21 is designed to facilitate the modeler to be fitted onto the upper / lower jaw of a rodent (mouse), and the pull wire 22 is designed to facilitate the application of force to pull open the animal's upper and lower jaws, thereby opening the animal's oral cavity and exposing the molars used to create the periodontitis model.

[0036] In a specific embodiment, the pull wire 22 is a medical nylon thread, which has an elastic buffering effect and significantly reduces the risk of mechanical damage to the gums.

[0037] In a specific embodiment, the tool body 1 is provided with a handle 4, which is located between the opening 2 and the wire holding part 3, so that the operator can hold the rodent periodontitis modeler to perform related operations.

[0038] In a specific embodiment, the tool body 1 is made of nickel-titanium alloy. Nickel-titanium alloy has high rigidity, which can avoid impact on the periodontal area during the modeling process due to insufficient rigidity of the tool body. At the same time, nickel-titanium alloy is lightweight, which can reduce hand fatigue when operating by hand.

[0039] The process of establishing a mouse periodontitis model using this rodent periodontitis modeler is as follows:

[0040] 1. Place the experimental animal (mouse) on the operating table and fix its head and torso with adjustable clamps. Select a suitable size of this non-invasive rodent periodontitis modeler (suitable for rats or mice) according to experimental requirements, such as... Figure 6 As shown, the upper and lower jaws of the mouse are opened using the open end of this rodent periodontitis modeler. Holding the handle, the concave groove 21 is placed on the upper / lower jaw of the mouse. The string is placed at the incisor. The rodent periodontitis modeler is pulled to both sides by external force until the mouse's mouth is opened to a suitable angle, exposing the target tooth area.

[0041] 2. Take another rodent periodontitis modeler, place the suture in the suture groove 31 of the suture holding part 3, and the operator extends the suture holding part 3 to the position of the molar to be modeled in the mouse's mouth (mesi-buccal part of the tooth), with the groove opening of the suture holding part 31 facing downwards. Apply downward force to the suture on both sides of the rodent periodontitis modeler. Since the groove wall of the suture holding part 31 is outwardly flared, only a slight downward force is needed to push the suture out of the suture holding part 31, so that the suture is separated from the rodent periodontitis modeler and pressed into the molar interdental space. Repeat this step to send the suture into the interdental space on the other side of the molar (distal-buccal part), so that the suture is wrapped around the neck line of the molar. The rodent periodontitis modeler is then removed from the mouse's mouth. Finally, the suture is knotted to complete the periodontal suture fixation.

[0042] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of this utility model, and are not intended to limit it. Although the utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some or all of the technical features therein. Such modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of this utility model.

Claims

1. A rodent periodontitis modeler, characterized in that, It includes the tool body (1), the opening (2), and the line holding part (3); The opening (2) and the thread-holding part (3) are respectively located at both ends of the tool body (1). The opening (2) is used to fit over the upper or lower jaw of the animal and to open the upper and lower jaws of the animal so that the animal's molars are exposed. The wire holding part (3) has a wire holding groove (31), and the width of the wire holding groove (31) gradually increases from the inner side to the outer side of the groove opening.

2. The rodent periodontitis modeler according to claim 1, characterized in that, The inner sidewall of the wire holding groove (31) extends obliquely from the inside to the outside, making the wire holding groove (31) outwardly flared. The inner sidewall of the wire holding groove (31) forms an angle θ with the vertical direction, where θ is 12°.

3. The rodent periodontitis modeler according to claim 1, characterized in that, The outer wall of the thread-holding part (3) is arc-shaped and can fit against the side tooth surface of the animal's tooth.

4. The rodent periodontitis modeler according to claim 1, characterized in that, The opening (2) includes a concave groove (21) at the end of the tool body (1) and a pull wire (22) at the opening of the concave groove (21).

5. The rodent periodontitis modeler according to claim 4, characterized in that, The pull wire (22) is a medical nylon thread.

6. The rodent periodontitis modeler according to claim 1, characterized in that, The tool body (1) is provided with a handle (4), which is located between the opening (2) and the wire holding part (3).

7. The rodent periodontitis modeler according to claim 1, characterized in that, The tool body (1) is made of nickel-titanium alloy.

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